289-80-5 | Pyridazine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$12.00	$8.00
5g	98%	in stock	$16.00	$11.00
10g	98%	in stock	$19.00	$13.00
25g	98%	in stock	$36.00	$25.00
100g	98%	in stock	$130.00	$91.00
500g	98%	in stock	$500.00	$350.00

Description

• Catalog Number: AB46958
• Chemical Name: Pyridazine
• CAS Number: 289-80-5
• Molecular Formula: C4H4N2
• Molecular Weight: 80.088
• MDL Number: MFCD28101229
• SMILES: c1ccnnc1
• NSC Number: 90792

Computed Properties

• Complexity: 30.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• XLogP3: -0.7

Literature

• Imidazopyridazine hepatitis C virus polymerase inhibitors. Structure-activity relationship studies and the discovery of a novel, traceless prodrug mechanism.

  Journal of medicinal chemistry 20140313

• Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7).

  Bioorganic & medicinal chemistry letters 20121201

• Cadmium(II) chloride, bromide and iodide complexes with 4,4'-bipyridazine: when are diazine and halide bridges (in)compatible?

  Acta crystallographica. Section C, Crystal structure communications 20121101

• 1-[4-(4-Chloro-phen-yl)piperazin-1-yl]-3-(6-oxo-3,4-diphenyl-1,6-dihydro-pyridazin-1-yl)propan-1-one.

  Acta crystallographica. Section E, Structure reports online 20120901

• Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.

  Bioorganic & medicinal chemistry letters 20120801

• 6-Oxo-1,6-dihydro-pyridazine-3-carbaldehyde monohydrate.

  Acta crystallographica. Section E, Structure reports online 20120801

• Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors.

  Bioorganic & medicinal chemistry letters 20120715

• Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties.

  Bioorganic & medicinal chemistry 20120715

• Hydrogen bonding and reactivity of water to azines in their S1 (n,π*) electronic excited states in the gas phase and in solution.

  Physical chemistry chemical physics : PCCP 20120707

• One-pot synthesis of phthalazines and pyridazino-aromatics: a novel strategy for substituted naphthalenes.

  Organic letters 20120706

• Bis(methanol-1κO)tetra-μ-pyridazine-1:2κ(4)N:N';2:3κ(4)N:N'-di-μ-thio-cyanato-1:2κ(2)N:N;2:3κ(2)N:N-tetrathio-cyanato-1κ(2)N,3κ(2)N-trinickel(II) methanol tetra-solvate.

  Acta crystallographica. Section E, Structure reports online 20120701

• Tetra-kis(pyridazine-κN)bis-(seleno-cyanato-κN)cobalt(II) pyridazine disolvate.

  Acta crystallographica. Section E, Structure reports online 20120701

• Tetra-kis(pyridazine-κN)bis-(seleno-cyanato-κN)nickel(II) pyridazine disolvate.

  Acta crystallographica. Section E, Structure reports online 20120701

• Diazine indole acetic acids as potent, selective, and orally bioavailable antagonists of chemoattractant receptor homologous molecule expressed on Th2 cells (CRTH2) for the treatment of allergic inflammatory diseases.

  Journal of medicinal chemistry 20120614

• Tetra-kis(pyridazine-κN)bis-(thio-cyanato-κN)nickel(II) pyridazine disolvate.

  Acta crystallographica. Section E, Structure reports online 20120601

• 6-Benz-yloxy-2-phenyl-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20120601

• 2-tert-Butyl-4-chloro-5-[4-(2-fluoro-eth-oxy)benz-yloxy]pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20120601

• Unravelling the reaction mechanism of the reductive ring contraction of 1,2-pyridazines.

  The Journal of organic chemistry 20120518

• Structure-based design of novel pyrimido[4,5-c]pyridazine derivatives as dihydropteroate synthase inhibitors with increased affinity.

  ChemMedChem 20120501

• Synthesis and fungicidal activity of tubulin polymerisation promoters. Part 2: pyridazines.

  Bioorganic & medicinal chemistry 20120501

• Bis(dicyanamido-κN)tetra-kis-(pyridazine-κN)nickel(II).

  Acta crystallographica. Section E, Structure reports online 20120501

• C-H bond strengths and acidities in aromatic systems: effects of nitrogen incorporation in mono-, di-, and triazines.

  Journal of the American Chemical Society 20120418

• Poly[hydrazin-1-ium [diaqua-bis-(μ(4)-pyridazine-3,6-dicarboxyl-ato)trilithate] monohydrate].

  Acta crystallographica. Section E, Structure reports online 20120401

• 2-[(1-Methyl-1H-pyrrol-2-yl)methyl-idene]propane-dinitrile.

  Acta crystallographica. Section E, Structure reports online 20120401

• Electrochemical, computational, and photophysical characterization of new luminescent dirhenium-pyridazine complexes containing bridging OR or SR anions.

  Inorganic chemistry 20120305

• Bis(hydrazin-1-ium) bis-(μ(2)-pyridazine-3,6-dicarboxyl-ato)bis-(aqua-lithiate) octa-aqua-bis-(μ(3)-pyridazine-3,6-dicarboxyl-ato)tetra-lithium.

  Acta crystallographica. Section E, Structure reports online 20120301

• 4-Oxo-2,4-diphenyl-butane-nitrile.

  Acta crystallographica. Section E, Structure reports online 20120301

• 2-(4-Meth-oxy-phen-yl)-4-oxo-4-phenyl-butane-nitrile.

  Acta crystallographica. Section E, Structure reports online 20120301

• Ultrafast resonance-enhanced multiphoton ionization in the azabenzenes: pyridine, pyridazine, pyrimidine, and pyrazine.

  The Journal of chemical physics 20120207

• Synthesis and herbicidal activities of novel 3-(substituted benzyloxy or phenoxy)-6-methyl-4-(3-trifluoromethylphenyl)pyridazine derivatives.

  Pest management science 20120201

• 6-Chloro-N-(2-meth-oxy-phen-yl)pyridazin-3-amine.

  Acta crystallographica. Section E, Structure reports online 20120201

• New cadmium thio- and selenocyanato coordination compounds: structural snapshots on the reaction pathway to more condensed anionic networks.

  Dalton transactions (Cambridge, England : 2003) 20120107

• Comprehensive and facile synthesis of some functionalized bis-heterocyclic compounds containing a thieno[2,3-b]thiophene motif.

  International journal of molecular sciences 20120101

• Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazone derivatives containing a pyridine moiety.

  Chemistry Central journal 20120101

• Some recent approaches of biologically active substituted pyridazine and phthalazine drugs.

  Current medicinal chemistry 20120101

• Application of 2-trichloromethylbenzimidazole in analytical chemistry: a highly selective chromogenic reagent for thin-layer chromatography and some other analytical uses.

  Journal of analytical methods in chemistry 20120101

• Pyridazine based scorpionate ligand in a copper boratrane compound.

  Inorganic chemistry 20111219

• 1-Benzoyl-4-(4-methyl-phen-yl)phthal-azine.

  Acta crystallographica. Section E, Structure reports online 20111201

• Cytotoxicity and gene expression profiles of novel synthesized steroid derivatives as chemotherapeutic anti-breast cancer agents.

  Bioorganic & medicinal chemistry 20111115

• An analysis of the isomerization energies of 1,2-/1,3-diazacyclobutadiene, pyrazole/imidazole, and pyridazine/pyrimidine with the turn-upside-down approach.

  The Journal of organic chemistry 20111104

• Discovery of a novel class of orally active antifungal beta-1,3-D-glucan synthase inhibitors.

  Antimicrobial agents and chemotherapy 20111101

• Modular strategy for the construction of radiometalated antibodies for positron emission tomography based on inverse electron demand Diels-Alder click chemistry.

  Bioconjugate chemistry 20111019

• Comparison of polarizable continuum model and quantum mechanics/molecular mechanics solute electronic polarization: study of the optical and magnetic properties of diazines in water.

  The Journal of chemical physics 20111014

• Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.

  Bioorganic & medicinal chemistry letters 20111001

• catena-Poly[[μ(2)-aqua-diaqua-bis-(μ(4)-pyridazine-3,6-dicarboxyl-ato)tetra-lithium] monohydrate].

  Acta crystallographica. Section E, Structure reports online 20111001

• 6-Chloro-3-(3-methyl-phen-yl)-1,2,4-triazolo[4,3-b]pyridazine.

  Acta crystallographica. Section E, Structure reports online 20111001

• Mono- and bis-quinidine organocatalysts in the asymmetric methanolysis of cis-1,2,3,6-tetrahydrophthalic anhydride: a conformational and mechanistic NMR study.

  Chirality 20111001

• Small-molecule androgen receptor downregulators as an approach to treatment of advanced prostate cancer.

  Bioorganic & medicinal chemistry letters 20110915

• 4-(3,7-Dimethyl-4-oxo-4,5-dihydro-isoxazolo[4,5-d]pyridazin-5-yl)benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110901

• 2,7-Dimethyl-1,3-thia-zolo[4,5-d]pyridazin-4(5H)-one.

  Acta crystallographica. Section E, Structure reports online 20110901

• Bromopyridazinedione-mediated protein and peptide bioconjugation.

  Chemical communications (Cambridge, England) 20110821

• Palladium-catalyzed asymmetric allylic alkylations of polynitrogen-containing aromatic heterocycles.

  Journal of the American Chemical Society 20110817

• Pyridazine- versus pyridine-based tridentate ligands in first-row transition metal complexes.

  Inorganic chemistry 20110815

• Rotational spectrum of asymmetric top molecules in combined static and laser fields.

  The Journal of chemical physics 20110814

• Mechanistic insight into olefin epoxidation catalyzed by rhenium(V) oxo complexes that contain pyridazine-based ligands.

  Inorganic chemistry 20110801

• catena-Poly[[dibromidomercury(II)]-μ-3,6-bis-(2-pyridyl-sulfan-yl)pyridazine-κN:N].

  Acta crystallographica. Section E, Structure reports online 20110801

• 2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus.

  Bioorganic & medicinal chemistry letters 20110715

• Pyridazine-derived γ-secretase modulators.

  Bioorganic & medicinal chemistry letters 20110701

• Poly[di-μ(2)-aqua-μ(2)-(5-methyl-pyrazine-2-carboxyl-ato)-(5-methyl-pyrazine-2-carboxyl-ato)-μ(3)-nitrato-trilithium].

  Acta crystallographica. Section E, Structure reports online 20110701

• 4-(2,7-Dimethyl-4-oxo-1,3-thia-zolo[4,5-d]pyridazin-5-yl)benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110701

• 6-Methyl-2-phenyl-4,5-dihydro-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20110701

• Ab initio theoretical study of non-covalent adsorption of aromatic molecules on boron nitride nanotubes.

  Physical chemistry chemical physics : PCCP 20110628

• Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract.

  Interdisciplinary toxicology 20110601

• S,S'-(Pyridazine-3,6-di-yl)dithio-uronium dichloride methanol monosolvate.

  Acta crystallographica. Section E, Structure reports online 20110601

• Bis(pyridazine-κN)bis-(seleno-cyanato-κN)zinc.

  Acta crystallographica. Section E, Structure reports online 20110501

• 2-Benzyl-6-benz-yloxypyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20110501

• Methyl 4-{[6-(4-bromo-phen-yl)-3-oxo-2,3,4,5-tetra-hydro-pyridazin-4-yl]methyl}benzoate.

  Acta crystallographica. Section E, Structure reports online 20110501

• Poly[aqua-(μ(3)-pyridazine-4-carboxyl-ato-κO:O:O')lithium].

  Acta crystallographica. Section E, Structure reports online 20110401

• 3-Chloro-6-[2-(cyclo-pentyl-idene)hydrazin-1-yl]pyridazine.

  Acta crystallographica. Section E, Structure reports online 20110401

• Novel pyridazine based scorpionate ligands in cobalt and nickel boratrane compounds.

  Inorganic chemistry 20110307

• Pd- and Ni-catalyzed cross-coupling reactions of functionalized organozinc reagents with unsaturated thioethers.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110301

• trans-Tetra-aqua-bis-(pyridazine-4-car-box-yl-ato-κO)magnesium(II) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20110301

• 2-Chloro-1-[4-(2-fluoro-benz-yl)piperazin-1-yl]ethanone.

  Acta crystallographica. Section E, Structure reports online 20110301

• Pharmacophore-based design, synthesis, and biological evaluation of novel chloro-pyridazine piperazines as human rhinovirus (HRV-3) inhibitors.

  Bioorganic & medicinal chemistry letters 20110201

• trans-Diaqua-(pyridazine-3-carboxyl-ato-κN,O)lithium.

  Acta crystallographica. Section E, Structure reports online 20110201

• Directed synthesis of μ-1,3,5 bridged dicyanamides by thermal decomposition of μ-1,5 bridged precursor compounds.

  Dalton transactions (Cambridge, England : 2003) 20110128

• The synthesis, X-ray crystal structure and optical properties of novel 5-aryl-3-ferrocenyl-1-pyridazinyl-pyrazoline derivatives.

  Journal of fluorescence 20110101

• GABAA receptor subtype-selective modulators. II. α5-selective inverse agonists for cognition enhancement.

  Current topics in medicinal chemistry 20110101

• GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics.

  Current topics in medicinal chemistry 20110101

• A new and efficient synthetic route for the anxiolytic agent CL285032.

  Bioorganic & medicinal chemistry letters 20110101

• Lanthanide Complexes of Substituted β-Diketone Hydrazone Derivatives: Synthesis, Characterization, and Biological Activities.

  Bioinorganic chemistry and applications 20110101

• Neglected disease - african sleeping sickness: recent synthetic and modeling advances.

  Scientia pharmaceutica 20110101

• Molecular recognition effects in atomistic models of imprinted polymers.

  International journal of molecular sciences 20110101

• Synthesis and Antimicrobial Activities of Some New Azetidin-2-ones and Thiazolidin-4-ones.

  Indian journal of pharmaceutical sciences 20110101

• A study of the vaporization enthalpies of some 1-substituted imidazoles and pyrazoles by correlation-gas chromatography.

  The journal of physical chemistry. B 20101223

• Hexaaqua-magnesium(II) bis-(pyridinium-2,6-dicarboxyl-ate).

  Acta crystallographica. Section E, Structure reports online 20101201

• Diclomezine: 6-(3,5-dichloro-4-methyl-phen-yl)pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20101201

• Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.

  Bioorganic & medicinal chemistry letters 20101115

• Synthesis and antituberculosis activity of some new pyridazine derivatives. Part II.

  European journal of medicinal chemistry 20101101

• Bis[[(6-carb-oxy-pyridazine-3-carboxyl-ato-κN,O)lithium]-μ-penta-hydrogen-dioxy-gen(1+)].

  Acta crystallographica. Section E, Structure reports online 20101101

• Expanding the diversity of allosteric bcr-abl inhibitors.

  Journal of medicinal chemistry 20101014

• DFT study of cycloparaphenylenes and heteroatom-substituted nanohoops.

  The Journal of organic chemistry 20101001

• 4-(4-Pyrid-yl)pyridinium penta-aqua(pyridazine-4,5-dicarboxyl-ato)praseodymate(III).

  Acta crystallographica. Section E, Structure reports online 20101001

• 3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine.

  Acta crystallographica. Section E, Structure reports online 20101001

• 1-(3-Bromo-2-thien-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20101001

• Synthesis of pyridazine and thiazole analogs as SGLT2 inhibitors.

  Bioorganic & medicinal chemistry 20100815

• Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain.

  Bioorganic & medicinal chemistry letters 20100801

• Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.

  Bioorganic & medicinal chemistry letters 20100801

• Pyridazinopsoralens of wide chemotherapeutic interest.

  Bioorganic & medicinal chemistry 20100801

• catena-Poly[[μ(3)-hydroxido-tetra-μ(2)-pyrid-azine-1:2κN:N';1:3κN:N';2:3κN:N'-tetrakis(selenocyanato)-1κN,2κN,3κN-trizinc(II)]-μ-cyanido-1:2'κC:N].

  Acta crystallographica. Section E, Structure reports online 20100801

• N-(4-Methyl-phen-yl)-6-(pyrazol-1-yl)pyridazin-3-amine.

  Acta crystallographica. Section E, Structure reports online 20100801

• 3-Chloro-6-[(E)-2-(1-phenyl-ethyl-idene)hydrazin-yl]pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100801

• Synthesis of new pyridazine-based monomers and related polymers for photovoltaic applications.

  Macromolecular rapid communications 20100616

• Synthesis, characterization and antihypertensive activity of pyridazinone derivatives.

  European journal of medicinal chemistry 20100601

• Synthesis and cyclooxygenase inhibitory activities of some N-acylhydrazone derivatives of isoxazolo[4,5-d]pyridazin-4(5H)-ones.

  European journal of medicinal chemistry 20100601

• Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: Pyridazinylmethylphenyl glucoside congeners.

  Bioorganic & medicinal chemistry letters 20100601

• 3-(Piperidin-1-yl)-6-(1H-pyrazol-1-yl)pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100601

• N-Phenyl-6-(1H-pyrazol-1-yl)pyridazin-3-amine.

  Acta crystallographica. Section E, Structure reports online 20100601

• Lewis-base adducts of 9,10-dihydro-9,10-diboraanthracene: ditopic hydroboration reagents and a B-N analogue of triptycene.

  Chemical communications (Cambridge, England) 20100528

• 1H, 13C, and 15N NMR spectra of some pyridazine derivatives.

  Magnetic resonance in chemistry : MRC 20100501

• Tautomerism and isotopic multiplets in the 13C NMR spectra of partially deuterated 3-arylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones and their sulfur analogs--evidence for elucidation of the structure backbone and tautomeric forms.

  Magnetic resonance in chemistry : MRC 20100401

• Reactivity and synthetic applications of 4,5-dicyanopyridazine: an overview.

  Molecules (Basel, Switzerland) 20100312

• Total synthesis of lycogarubin C and lycogalic acid.

  Organic letters 20100305

• 3-Chloro-6-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100301

• 3-Chloro-6-{4-[3-(4-chloro-phen-oxy)prop-yl]piperazin-1-yl}pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100301

• catena-Poly[lead(II)-bis-(μ(2)-pyridazine-3-carboxyl-ato-κN,O:O)].

  Acta crystallographica. Section E, Structure reports online 20100201

• Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438).

  Bioorganic & medicinal chemistry letters 20100115

• Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain.

  Bioorganic & medicinal chemistry letters 20100115

• Pyridazine-based Schiff base ligands with N4OxS2 (x=2, 4) donor set atoms: synthesis, characterization, spectral studies and 13C chemical shifts computed by the GIAO-DFT and CSGT-DFT methodologies.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100101

• Adsorption and quantum chemical studies on the inhibition potentials of some thiosemicarbazides for the corrosion of mild steel in acidic medium.

  International journal of molecular sciences 20100101

• Studies on the reactivity of (9-Methyl-5,6-dihydronaphtho[1â,2â:4,5]-thieno[2,3-d]pyrimidin-11-yl)hydrazine towards some reagents for biological evaluation.

  Scientia pharmaceutica 20100101

• 3-Chloro-6-[4-(2-pyrid-yl)piperazin-1-yl]pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100101

• Further studies on arylpiperazinyl alkyl pyridazinones: discovery of an exceptionally potent, orally active, antinociceptive agent in thermally induced pain.

  Journal of medicinal chemistry 20091210

• Ligand-based modification of the structures and optical properties of new silver(I)-rhenate(VII) oxide/organic hybrid solids.

  Inorganic chemistry 20091207

• 4,5-Dichloro-2-methyl-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20091201

• Synthesis, characterization, and rotational dynamics of crystalline molecular compasses with N-heterocyclic rotators.

  The Journal of organic chemistry 20091120

• Phthalocyanine-C60 fused conjugates exhibiting molecular orbital interactions depending on the solvent polarity.

  Chemistry, an Asian journal 20091102

• Di-μ-aqua-bis-(μ-pyridazine-4-carboxyl-ato-κN:N')bis-[triaqua-(pyridazine-4-carboxyl-ato-κO,O')lead(II)] dihydrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• Design and synthesis of urea-linked aromatic oligomers--a route towards convoluted foldamers.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091005

• Synthesis and antifungal activity of 5-chloro-6-phenylpyridazin-3(2H)-one derivatives.

  Molecules (Basel, Switzerland) 20090918

• The search for new COX-2 inhibitors: a review of 2002 - 2008 patents.

  Expert opinion on therapeutic patents 20090901

• Mechanisms for formation of diazocinones, pyridazines, and pyrazolines from tetrazines--oxyanion-accelerated pericyclic cascades?

  The Journal of organic chemistry 20090703

• The structure-AChE inhibitory activity relationships study in a series of pyridazine analogues.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20090701

• N-(2-Methyl-phen-yl)-6-(1H-pyrazol-1-yl)pyridazin-3-amine.

  Acta crystallographica. Section E, Structure reports online 20090701

• Metabolism of flufenpyr-ethyl in rats and mice.

  Journal of agricultural and food chemistry 20090610

• trans-Diaqua-bis(6-methoxycarbonyl-pyridazine-3-carboxyl-ato-κN,O)zinc(II) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20090601

• 4-Benzyl-6-p-tolyl-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20090601

• Diels-Alder reactions of 3,6-disubstituted 1,2,4,5-tetrazines. Synthesis and X-ray crystal structures of diazafluoranthene derivatives.

  Organic & biomolecular chemistry 20090521

• Novel pyridazine derivatives: Synthesis and antimicrobial activity evaluation.

  European journal of medicinal chemistry 20090501

• A new dinuclear ruthenium complex as an efficient water oxidation catalyst.

  Inorganic chemistry 20090406

• New pyridazine derivatives: synthesis, chemistry and biological activity.

  Bioorganic & medicinal chemistry 20090401

• Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands.

  Journal of inorganic biochemistry 20090301

• Ab initio study of the interactions between CO(2) and N-containing organic heterocycles.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20090202

• 2,2,7,7-Tetra-methyl-1,2,3,6,7,8-hexa-hydro-cinnolino[5,4,3-cde]cinnoline.

  Acta crystallographica. Section E, Structure reports online 20090201

• 1,2,3,6,7,8-Hexahydro-cinnolino[5,4,3-cde]cinnoline.

  Acta crystallographica. Section E, Structure reports online 20090201

• A glow in the dark: synthesis and electropolymerization of a novel chemiluminescent terthienyl system.

  Chemical communications (Cambridge, England) 20090121

• A novel and convenient protocol for synthesis of pyridazines.

  Organic letters 20090115

• Synthesis and evaluation of novel chloropyridazine derivatives as potent human rhinovirus (HRV) capsid-binding inhibitors.

  Bioorganic & medicinal chemistry 20090115

• Microwave assisted reactions of some azaheterocylic compounds.

  Molecules (Basel, Switzerland) 20090115

• Assessment of 18F-labeled mitochondrial complex I inhibitors as PET myocardial perfusion imaging agents in rats, rabbits, and primates.

  European journal of nuclear medicine and molecular imaging 20090101

• Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone.

  Angewandte Chemie (International ed. in English) 20090101

• Two-photon excitation behavior of thiophene-based oligomers and a polymer.

  Journal of nanoscience and nanotechnology 20090101

• The reaction of beta-amino-alpha,gamma-dicyanocrotononitrile with acetophenone: synthesis of pyridine, pyridazine and thiophene derivatives with antimicrobial activities.

  Acta pharmaceutica (Zagreb, Croatia) 20081201

• Lithium salt electride with an excess electron pair--a class of nonlinear optical molecules for extraordinary first hyperpolarizability.

  The journal of physical chemistry. A 20081113

• A general method for copper-catalyzed arylation of arene C-H bonds.

  Journal of the American Chemical Society 20081112

• 1,2-Diazinium hydrogen chloranilate.

  Acta crystallographica. Section E, Structure reports online 20081101

• Potassium t-butoxide alone can promote the biaryl coupling of electron-deficient nitrogen heterocycles and haloarenes.

  Organic letters 20081016

• Structure of pyridazine in the S1 state: experiment and theory.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20080804

• 4-Carboxy-pyridazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20080801

• Copper(II) bromide and copper(II) acetate complexes of 4,4'-(p-phenylene)bipyridazine.

  Acta crystallographica. Section C, Crystal structure communications 20080701

• Methyl 3-(4-{6-methyl-4-[3-(trifluoro-meth-yl)phen-yl]pyridazin-3-yl-oxy}phen-yl)propanoate.

  Acta crystallographica. Section E, Structure reports online 20080601

• Encapsulation and dynamic behavior of two H2 molecules in an open-cage C70.

  Journal of the American Chemical Society 20080528

• A new class of luminescent tricarbonyl rhenium(I) complexes containing bridging 1,2-diazine ligands: electrochemical, photophysical, and computational characterization.

  Inorganic chemistry 20080519

• Screening and evaluation of antioxidant activity of some pyridazine derivatives.

  Journal of enzyme inhibition and medicinal chemistry 20080401

• Potential use of antiviral agents in polio eradication.

  Emerging infectious diseases 20080401

• 6-Methyl-2-p-tolyl-4-[3-(trifluoro-meth-yl)phen-yl]pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20080401

• Biphenyl versus phenylpyridazine derivatives: the role of the heterocycle in a series of acyl-CoA:cholesterol acyl transferase inhibitors.

  Journal of medicinal chemistry 20080313

• Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activity.

  Acta pharmaceutica (Zagreb, Croatia) 20080301

• 1-Methyl-2-(4-methyl-phen-yl)-4-morpholinopyridazine-3,6(1H,2H)-dione.

  Acta crystallographica. Section E, Structure reports online 20080201

• Hydrazinediium bis-(6-carboxy-pyridazine-3-carboxyl-ate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20080201

• 4-[3-(Trifluoro-meth-yl)phen-yl]-5,6,7,8-tetra-hydro-cinnolin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20080201

• The C 1s and N 1s near edge x-ray absorption fine structure spectra of five azabenzenes in the gas phase.

  The Journal of chemical physics 20080128

• Self-assembly of ligands designed for the building of a new type of [2 x 2] metallic grid. anion encapsulation and diffusion NMR spectroscopy.

  Inorganic chemistry 20080121

• Synthesis, herbicidal activities, and 3D-QSAR of 2-cyanoacrylates containing aromatic methylamine moieties.

  Journal of agricultural and food chemistry 20080109

• Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.

  BMC pharmacology 20080101

• The p38alpha mitogen-activated protein kinase as a central nervous system drug discovery target.

  BMC neuroscience 20080101

• Synthesis and monoamine oxidase inhibitory activity of new pyridazine-, pyrimidine- and 1,2,4-triazine-containing tricyclic derivatives.

  Journal of medicinal chemistry 20071101

• Silylenes: a unified picture of their stability, acid-base and spin properties, nucleophilicity, and electrophilicity via computational and conceptual density functional theory.

  The journal of physical chemistry. A 20071025

• Copper(I) cyanide networks: synthesis, luminescence behavior and thermal analysis. Part 1. Diimine ligands.

  Inorganic chemistry 20071015

• How to model solvent effects on molecular properties using quantum chemistry? Insights from polarizable discrete or continuum solvation models.

  The journal of physical chemistry. A 20071004

• Silver(I) ions bridged by pyridazine: doubling the ligand functionality for the design of unusual 3D coordination frameworks.

  Dalton transactions (Cambridge, England : 2003) 20070921

• Supramolecular self-assembled polynuclear complexes from tritopic, tetratopic, and pentatopic ligands: structural, magnetic and surface studies.

  Inorganic chemistry 20070917

• Synthesis of pyridazine-based scaffolds as alpha-helix mimetics.

  Organic letters 20070913

• Transferable potentials for phase equilibria. 9. Explicit hydrogen description of benzene and five-membered and six-membered heterocyclic aromatic compounds.

  The journal of physical chemistry. B 20070913

• Type 2 intramolecular N-acylazo Diels-Alder reaction: regio- and stereoselective synthesis of bridgehead bicyclic 1,2-diazines.

  The Journal of organic chemistry 20070831

• Lithium-mediated zincation of pyrazine, pyridazine, pyrimidine, and quinoxaline.

  The Journal of organic chemistry 20070817

• CoMFA based de novo design of pyridazine analogs as PTP1B inhibitors.

  Journal of molecular graphics & modelling 20070701

• Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Silver(I) sulfate coordination polymers with 4,4'-bipyridazine and pyridazino[4,5-d]pyridazine.

  Acta crystallographica. Section C, Crystal structure communications 20070601

• Targeting inhibition of COX-2: a review of patents, 2002-2006.

  Recent patents on inflammation & allergy drug discovery 20070601

• 13C-1H HSQC experiment of probe molecules aligned in thermotropic liquid crystals: sensitivity and resolution enhancement in the indirect dimension.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20070401

• A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.

  Journal of neuroinflammation 20070101

• Luminescent hydrido-carbonyl clusters of rhenium containing bridging 1,2-diazine ligands.

  Inorganic chemistry 20061225

• A self-assembled hexadecanuclear 4 x[2 x 2] Mn(II)16 square grid from a pyridazine bis(hydrazone) ligand: synthesis, structure and magnetism.

  Chemical communications (Cambridge, England) 20061221

• Metal-organic frameworks exhibiting strong anion-pi interactions.

  Chemical communications (Cambridge, England) 20061214

• Estimation of local density augmentation and hydrogen bonding between pyridazine and water under sub- and supercritical conditions using UV-vis spectroscopy.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20061101

• Donor-acceptor-donor-type liquid crystal with a pyridazine core.

  Organic letters 20061012

• A computational study on pi and sigma modes of metal ion binding to heteroaromatics (CH)(5-m)X(m) and (CH)(6-m)X(m) (X = N and P): contrasting preferences between nitrogen- and phosphorous-substituted rings.

  The journal of physical chemistry. A 20060824

• Triphenylene analogues with B2N2C2 cores: synthesis, structure, redox behavior, and photophysical properties.

  Journal of the American Chemical Society 20060823

• Use of 4-bromo pyridazine 3,6-dione for building 3-amino pyridazine libraries.

  Molecular diversity 20060801

• 3-Benzidino-6(4-chlorophenyl) pyridazine blocks delayed rectifier and transient outward potassium current in acutely isolated rat hippocampal pyramidal neurons.

  Neuroscience letters 20060710

• Pulsed-field ionization electron spectroscopy and ab initio calculations of copper-diazine complexes.

  The Journal of chemical physics 20060707

• Copper complexes with heterocyclic sulfonamides: synthesis, spectroscopic characterization, microbiological and SOD-like activities: crystal structure of [Cu(sulfisoxazole)2(H2O)4] . 2H2O.

  Journal of inorganic biochemistry 20060701

• A thienopyridazinone-based melanin-concentrating hormone receptor 1 antagonist with potent in vivo anorectic properties.

  Journal of medicinal chemistry 20060629

• Kinetics and mechanism of the reactions of Pd(II) complexes with azoles and diazines. Crystal structure of [Pd(bpma)(H2O)](ClO4)2.2H2O.

  Dalton transactions (Cambridge, England : 2003) 20060628

• Anion-pi interactions as controlling elements in self-assembly reactions of Ag(I) complexes with pi-acidic aromatic rings.

  Journal of the American Chemical Society 20060503

• Determination of natural abundance 15N-1H and 13C-1H dipolar couplings of molecules in a strongly orienting media using two-dimensional inverse experiments.

  Magnetic resonance in chemistry : MRC 20060501

• A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.

  Journal of medicinal chemistry 20060420

• Vibrational spectroscopy of the pyridazine cation in the ground state.

  The journal of physical chemistry. A 20060302

• Pyrrolopyridazine MEK inhibitors.

  Bioorganic & medicinal chemistry letters 20060201

• Cadmium nitrate coordination polymers with substituted pyridazino[4,5-d]pyridazines.

  Acta crystallographica. Section C, Crystal structure communications 20060201

• Synthetic approaches to polypyridyl bridging ligands with proximal multidentate binding sites.

  The Journal of organic chemistry 20060106

• Monoclinic and triclinic concomitant polymorphs of di-mu-pyridazine-1kappa(2)N:2kappa(2)N'-bis[(saccharinato)silver(I)].

  Acta crystallographica. Section C, Crystal structure communications 20060101

• Current status of anti-picornavirus therapies.

  Current pharmaceutical design 20060101

• The in vivo metabolism of 3-oxo-5-benzylidene-6-methyl-(4H)-2-(benzoylmethyl)pyridazine in rats.

  European journal of drug metabolism and pharmacokinetics 20060101

• Hydrogen bond directed synthesis of pyridazine and naphthyridine containing macrocycles.

  Chemical communications (Cambridge, England) 20051214

• Synthesis of new series of 1-Aryl-1,4-dihydro-4-oxo-6-methyl pyridazine-3-carboxylic acid as potential antibacterial agents.

  European journal of medicinal chemistry 20051201

• Mono- or diphenylpyridazines connected to N-(2,4-difluorophenyl)-N'-heptylurea as acyl-CoA:cholesterol acyltransferase inhibitors.

  Journal of medicinal chemistry 20051201

• Interplay between intra- and interligand charge transfer with variation of the axial N-heterocyclic ligand in osmium(II) pyridylpyrazolate complexes: extensive color tuning by phosphorescent solvatochromism.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20051021

• Fully dimensional ab initio description of the structure and energetics of azabenzene-argon complexes.

  The Journal of chemical physics 20051015

• Cyclization reactions of acylium and thioacylium ions with isocyanates and isothiocyanates: gas phase synthesis of 3,4-dihydro-2,4-dioxo-2H-1,3,5-oxadiazinium ions.

  Journal of the American Society for Mass Spectrometry 20051001

• A new pyridazine series of GABAA alpha5 ligands.

  Journal of medicinal chemistry 20050922

• Vibrational spectra and potential energy distributions for 4,5-dichloro-3-hydroxypyridazine by density functional theory and normal coordinate calculations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050901

• Dye-sensitized photooxygenation of furanosyl furans: synthesis of a new pyridazine C-nucleoside.

  The Journal of organic chemistry 20050805

• Total synthesis of ningalin D.

  Journal of the American Chemical Society 20050803

• Dimetallic complexes of a structurally versatile pyridazine-containing Schiff-base macrocyclic ligand with pendant pyridine arms.

  Dalton transactions (Cambridge, England : 2003) 20050721

• Design and synthesis of potent pyridazine inhibitors of p38 MAP kinase.

  Bioorganic & medicinal chemistry letters 20050502

• Docking of 6-chloropyridazin-3-yl derivatives active on nicotinic acetylcholine receptors into molluscan acetylcholine binding protein (AChBP).

  Farmaco (Societa chimica italiana : 1989) 20050401

• Synthesis of 3-alkylthio-6-allylthiopyridazine derivatives and their antihepatocarcinoma activity.

  Archives of pharmacal research 20050401

• Validation of the neuroinflammation cycle as a drug discovery target using integrative chemical biology and lead compound development with an Alzheimer's disease-related mouse model.

  Current Alzheimer research 20050401

• Neutral Cu4N12 and Ag4N12 metallacycles with a para-cyclophane framework assembled from copper(I) and silver(I) pyrazolates and pyridazine.

  Chemical communications (Cambridge, England) 20050328

• 3,6-bis(2'-pyridyl)pyridazine (L) and its deprotonated form (L - H+)- as ligands for {(acac)2Ru(n+)} or {(bpy)2Ru(m+)}: investigation of mixed valency in [{(acac)2Ru}2(mu-L - H+)]0 and [{(bpy)2Ru}2(mu-L - H+)]4+ by spectroelectrochemistry and EPR.

  Dalton transactions (Cambridge, England : 2003) 20050221

• Synthesis and herbicidal activity of novel heterocyclic protoporphyrinogen oxidase inhibitors.

  Pest management science 20041201

• 5'-(2-phosphoryl-1,4-dioxobutane) as a product of 5'-oxidation of deoxyribose in DNA: elimination as trans-1,4-dioxo-2-butene and approaches to analysis.

  Chemical research in toxicology 20041101

• Pyridazine derivatives and related compounds. Part 13: Synthesis and antimicrobial activity of some pyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazines.

  Bioorganic & medicinal chemistry letters 20041004

• Zonal ablation of the olfactory sensory neuroepithelium of the mouse: effects on odorant detection.

  The European journal of neuroscience 20041001

• The influence of water on the rates of 1,3-dipolar cycloaddition reactions: trigger points for exponential rate increases in water-organic solvent mixtures. Water-super versus water-normal dipolarophiles.

  Journal of the American Chemical Society 20040929

• N-Phenyl-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amines as potent and selective inhibitors of glycogen synthase kinase 3 with good cellular efficacy.

  Journal of medicinal chemistry 20040909

• [A novel deprotonative functionalization of aromatics with phosphazene base].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040801

• Dimetallic complexes of acyclic pyridine-armed ligands derived from 3,6-diformylpyridazine.

  Dalton transactions (Cambridge, England : 2003) 20040721

• New derivatives of pyrrolo[3,4-d]pyridazinone and their anticancer effects.

  Farmaco (Societa chimica italiana : 1989) 20040601

• Novel enantiopure ferrugininoids active as nicotinic agents: synthesis and radioligand binding studies.

  Die Pharmazie 20040601

• Structural distortion of pyridazine in the 1(n, pi) excited state: evidence for local excitation.

  Chemphyschem : a European journal of chemical physics and physical chemistry 20040517

• Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels.

  Bioorganic & medicinal chemistry letters 20040503

• Synthesis of 5-azaindolizine derivatives by the palladium-catalyzed intermolecular formal [3+2] cycloaddition of alkylidenecyclopropanes with 1,2-diazines.

  The Journal of organic chemistry 20040430

• Realization of unusual ligand binding motifs in metalated container molecules: synthesis, structures, and magnetic properties of the complexes [(LMe)Ni2(mu-L')]n+ with L'=NO3-, NO2-, N3-, N2H4, pyridazine, phthalazine, pyrazolate, and benzoate.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040402

• Poly[[(pyridazine-kappaN)copper(I)]-micro(3)-thiocyanato-kappa(3)N:S:S].

  Acta crystallographica. Section C, Crystal structure communications 20040401

• Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.

  Journal of medicinal chemistry 20040311

• Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives: high-affinity ligands to the alpha 2 delta subunit of voltage gated calcium channels.

  Bioorganic & medicinal chemistry letters 20040308

• Mechanism of action of pyridazine analogues on protein tyrosine phosphatase 1B (PTP1B).

  Bioorganic & medicinal chemistry letters 20040223

• Lanthanide(III)/actinide(III) differentiation in coordination of azine molecules to tris(cyclopentadienyl) complexes of cerium and uranium.

  Dalton transactions (Cambridge, England : 2003) 20040221

• New developments in the symmetry-adapted algorithm of the Polarizable Continuum Model.

  Journal of computational chemistry 20040201

• Experimental validation of theoretical potassium and sodium cation affinities of amides by mass spectrometric kinetic method measurements.

  Rapid communications in mass spectrometry : RCM 20040101

• Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.

  Bioorganic & medicinal chemistry letters 20031117

• Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen.

  Drug metabolism and disposition: the biological fate of chemicals 20031101

• An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury.

  Bioorganic & medicinal chemistry letters 20031020

• Quaternary salts containing the pentafluorosulfanyl (SF5) group.

  Inorganic chemistry 20030922

• Synthesis and chemistry of unusual bicyclic endoperoxides containing the pyridazine ring.

  The Journal of organic chemistry 20030905

• Synthesis and evaluation of 5-arylated 2(5H)-furanones and 2-arylated pyridazin-3(2H)-ones as anti-cancer agents.

  The Journal of pharmacy and pharmacology 20030901

• Synthesis, crystal structures, and thermal and thermodynamic properties of dimorphic copper(I) coordination polymers.

  Inorganic chemistry 20030505

• Domino reactions of 4,5-dicyanopyridazine with dihydroheterocycles: synthetic and mechanistic features.

  The Journal of organic chemistry 20030418

• A study by ultraviolet spectroscopy on the self-association of diazines in aqueous solution.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030401

• Pyridazine derivatives 32: Stille-based approaches in the synthesis of 5-substituted-6-phenyl-3(2H)-pyridazinones.

  Chemical & pharmaceutical bulletin 20030401

• New isomeric azine-bridged dinuclear platinum(II) complexes circumvent cross-resistance to cisplatin.

  Journal of medicinal chemistry 20030327

• Three- and four-coordinate gold(I) complexes of 3,6-bis(diphenylphosphino)pyridazine: monomers, polymers, and a metallocryptand cage.

  Inorganic chemistry 20030324

• Synthesis and antiinflammatory activity of novel indazolones.

  Archives of pharmacal research 20030101

• [Investigation of antimycotic action of pyridazine derivatives].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101

• Cross-coupling reactions of phenylmagnesium halides with fluoroazines and fluorodiazines.

  The Journal of organic chemistry 20021213

• Inhibition of allergic dermal inflammation by the novel imidazopyridazine derivative TAK-427 in a guinea pig experimental model of eczema.

  The Journal of pharmacology and experimental therapeutics 20021201

• Synthesis and biological activity of a novel class of pyridazine analogues as non-competitive reversible inhibitors of protein tyrosine phosphatase 1B (PTP1B).

  Bioorganic & medicinal chemistry 20021001

• Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165.

  Journal of medicinal chemistry 20020718

• [Pyridazino(3,4-c)quinolines and pyridazino(4,5-c)quinolines--synthesis and investigation of lipoxygenase inhibition].

  Die Pharmazie 20020601

• Di-[1,10]-phenanthrolinyl diazines: a new family of bis-tridentate chelators.

  Organic letters 20020418

• Synthesis and nicotinic binding studies on enantiopure diazine analogues of the novel (2-chloro-5-pyridyl)-9-azabicyclo[4.2.1]non-2-ene UB-165.

  Journal of medicinal chemistry 20020227

• Pyridazine based inhibitors of p38 MAPK.

  Bioorganic & medicinal chemistry letters 20020225

• Syntheses and evaluation of pyridazine and pyrimidine containing bioisosteres of (+/-)-pyrido[3.4-b]homotropane and pyrido-[3.4-b]tropane as novel nAChR ligands.

  Bioorganic & medicinal chemistry 20020101

• Pyridazine derivatives and related compounds, part 9. tetrazolo[1,5-b]pyridazine-8-carbohydrazide: synthesis and some reactions.

  Bollettino chimico farmaceutico 20020101

• Novel 3-arylamino- and 3-cycloalkylamino-5, 6-diphenyl-pyridazines active as ACAT inhibitors.

  Archiv der Pharmazie 20020101

• Synthesis and evaluation of diazine containing bioisosteres of (-)-ferruginine as ligands for nicotinic acetylcholine receptors.

  Bioorganic & medicinal chemistry 20011001

• Binuclear complexes as building blocks for polynuclear complexes with high-spin ground states: synthesis and structure of a tetranuclear nickel complex with an S = 4 ground state.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20011001

• A meso-helical coordination polymer from achiral dinuclear [Cu2(H3CCN)2(micro-pydz)3][PF6]2 and 1,3-bis(diphenylphosphanyl)propane-synthesis and crystal structure of 1 to infinity Cu(mu-pydz)2][PF6 (pydz=pyridazine).

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010917

• Asymmetric total synthesis of ent-(-)-roseophilin: assignment of absolute configuration.

  Journal of the American Chemical Society 20010905

• Synthesis and bioactivities of novel pyridazine derivatives: inhibitors of interleukin-1 beta (IL-1beta) production.

  Bioorganic & medicinal chemistry letters 20010903

• Design, synthesis, and structure-activity relationships of a series of 3-[2-(1-benzylpiperidin-4-yl)ethylamino]pyridazine derivatives as acetylcholinesterase inhibitors.

  Journal of medicinal chemistry 20010816

• Synthesis of new salicylamide derivatives with evaluation of their antiinflammatory, analgesic and antipyretic activities.

  Archives of pharmacal research 20010601

• exo-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes: syntheses and nicotinic acetylcholine receptor agonist activity of potent pyridazine analogues of (+/-)-epibatidine.

  Journal of medicinal chemistry 20010104

• Bis[3,6-bis(6-methyl-2pyridyl)pyridazine-kappa2N2,N3]chlorocopper(II) perchlorate.

  Acta crystallographica. Section C, Crystal structure communications 20010101

• Synthesis of 5-substituted pyrrolo[1,2-b]pyridazines with antioxidant properties.

  Archiv der Pharmazie 20010101

• Evaluation of the excretion, and metabolism of the cardiotonic agent bemoradan in male rats and female beagle dogs.

  European journal of drug metabolism and pharmacokinetics 20010101