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Home  > 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, hydrochloride (1:2)

AB36108

289499-45-2 | 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, hydrochloride (1:2)

Packsize Purity Availability Price Discounted Price    Quantity
1mg 98% in stock $30.00 $21.00 -   +
5mg 98% in stock $48.00 $34.00 -   +
10mg 98% in stock $80.00 $56.00 -   +
25mg 98% in stock $173.00 $121.00 -   +
50mg 98% in stock $321.00 $225.00 -   +

*All products are for research use only and not intended for human or animal use.

*All prices are in USD.

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Description
Catalog Number: AB36108
Chemical Name: 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-, hydrochloride (1:2)
CAS Number: 289499-45-2
Molecular Formula: C24H26Cl2FN5O3
Molecular Weight: 522.3993432
MDL Number: MFCD09837878
SMILES: C=CC(=O)Nc1cc2c(ncnc2cc1OCCCN1CCOCC1)Nc1ccc(c(c1)Cl)F.Cl

 

Upstream Synthesis Route 
  • Canertinib dihydrochloride is a potent and selective irreversible inhibitor of the human epidermal growth factor receptor (EGFR) tyrosine kinase. Its application in chemical synthesis lies in its ability to specifically target and inhibit the activity of EGFR, a cell surface receptor that is overexpressed in various cancer cells. By blocking the activity of EGFR, Canertinib dihydrochloride can disrupt important signaling pathways involved in the growth and proliferation of cancer cells, ultimately leading to their suppression. This makes Canertinib dihydrochloride a valuable tool in the development of novel anticancer therapies and in the study of EGFR-related signaling mechanisms in cancer cells.
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