2935-35-5 | L-Phenylglycine

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$6.00	$4.00
25g	98%	in stock	$7.00	$5.00
100g	98%	in stock	$16.00	$11.00
500g	98%	in stock	$54.00	$38.00

Description

• Catalog Number: AB74999
• Chemical Name: L-Phenylglycine
• CAS Number: 2935-35-5
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.1626
• MDL Number: MFCD00064403
• SMILES: N[C@@H](c1ccccc1)C(=O)O

Computed Properties

• Complexity: 141
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -1.7

Literature

• Two plate-based colorimetric assays for screening α-amino acid ester hydrolase with high synthesis/hydrolysis ratio.

  Enzyme and microbial technology 20120715

• Immobilization of chitosan in sol-gel phases for chiral open-tubular capillary electrochromatography.

  Analytica chimica acta 20120309

• Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis.

  Journal of biotechnology 20110820

• Chiral recognition of α-amino acids by an optically active (2S,5S,8S,11S)-2,5,8,11-tetraethyl cyclen cobalt(III) complex.

  Inorganic chemistry 20110103

• A straightforward three-component synthesis of alpha-amino esters containing a phenylalanine or a phenylglycine scaffold.

  The Journal of organic chemistry 20100416

• Predominant (S)-enantioselective inclusion of aryl methyl sulfoxides by (S)-isoleucyl-(S)-phenylglycines.

  The Journal of organic chemistry 20100205

• Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR.

  Bioorganic & medicinal chemistry letters 20100101

• Evidence of D-phenylglycine as delivering tool for improving L-dopa absorption.

  Journal of biomedical science 20100101

• Synthesis of new imidazolidin-2,4-dione and 2-thioxoimidazolidin-4-ones via C-phenylglycine derivatives.

  Molecules (Basel, Switzerland) 20091230

• Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators.

  The Journal of pharmacology and experimental therapeutics 20090901

• Conformational study of jet-cooled L-phenylglycine.

  The Journal of chemical physics 20080514

• Solvent migration from the C- to the N-terminus of amino acid in photoionization of phenylglycine-water complex.

  The Journal of chemical physics 20080128

• Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine metabolism in Pseudomonas stutzeri ST-201.

  Biochimica et biophysica acta 20071101

• Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.

  Bioorganic & medicinal chemistry 20070201

• (L)-Phenylglycine, but not necessarily other alpha2delta subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats.

  Pain 20061101

• Metabolic engineering of the E. coli L-phenylalanine pathway for the production of D-phenylglycine (D-Phg).

  Metabolic engineering 20060501

• The conformers of phenylglycine.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060308

• Investigation and characterization of liquid two-phase systems for the separation of crystal mixtures by interfacial partitioning.

  Biotechnology and bioengineering 20060305

• Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.

  The Journal of biological chemistry 20060303

• Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

  Bioorganic & medicinal chemistry letters 20060301

• Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors.

  Bioorganic & medicinal chemistry letters 20051201

• Resolution of DL-Phenylglycine by Penicillin G acylase.

  Hindustan antibiotics bulletin 20050201

• Structural scaffold of 18-crown-6 tetracarboxylic acid for optical resolution of chiral amino acid: X-ray crystal analyses and energy calculations of complexes of D- and L-isomers of tyrosine, isoleucine, methionine and phenylglycine.

  Organic & biomolecular chemistry 20041207

• [Enantiomeric separation of mandelic acid and its analogues by high performance liquid chromatography with 2,6-di-O-pentyl-beta-cyclodextrin coated symmetry C8 column].

  Se pu = Chinese journal of chromatography 20040701

• Analogues of homoibotenic acid show potent and selective activity following sensitisation by quisqualic acid.

  European journal of pharmacology 20040319

• Determination of the enantiomeric composition of guest molecules by chemometric analysis of the UV-visible spectra of cyclodextrin guest-host complexes.

  Journal of the American Chemical Society 20030219

• Carbonic anhydrase inhibitors: synthesis of water soluble sulfonamides incorporating a 4-sulfamoylphenylmethylthiourea scaffold, with potent intraocular pressure lowering properties.

  Journal of enzyme inhibition and medicinal chemistry 20021001

• [Discussion of the application of three-point interaction principle to the phenylglycine racemic compound in IR spectrometry and its enantiomers separation in HPLC].

  Yao xue xue bao = Acta pharmaceutica Sinica 20020801

• Penicillin acylase-catalyzed ampicillin synthesis using a pH gradient: a new approach to optimization.

  Biotechnology and bioengineering 20020605

• Recovery of small bioparticles by interfacial partitioning.

  Biotechnology and bioengineering 20020520

• Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus.

  Biochemistry 20020430

• A study of the substrate specificity of Na+-dependent and Na+-independent neutral amino acid transport systems in dog intestinal brush-border membrane vesicles using L-alanine analogues.

  The Journal of pharmacy and pharmacology 20020401

• Determination of optical purity by nonenantioselective LC using CD detection.

  Journal of pharmaceutical and biomedical analysis 20011201

• The design of phenylglycine containing benzamidine carboxamides as potent and selective inhibitors of factor Xa.

  Bioorganic & medicinal chemistry letters 20010312