2942-40-7 | 4-Nitro-1H-indazole

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$8.00	$5.00
5g	95%	in stock	$19.00	$13.00
10g	95%	in stock	$29.00	$20.00
25g	95%	in stock	$70.00	$49.00
100g	95%	in stock	$279.00	$195.00

Description

• Catalog Number: AB37596
• Chemical Name: 4-Nitro-1H-indazole
• CAS Number: 2942-40-7
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.1335
• MDL Number: MFCD00022784
• SMILES: [O-][N+](=O)c1cccc2c1cn[nH]2
• NSC Number: 96892

Computed Properties

• Complexity: 192
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.4

Upstream Synthesis Route

4-Nitro-1H-indazole, also known as $name$, is a versatile compound widely used in chemical synthesis. One of its key applications is in the field of medicinal chemistry, where it serves as a valuable building block for the synthesis of various pharmaceutical compounds. The nitro group on the 4-position of the indazole ring makes it a valuable intermediate for the preparation of biologically active molecules.In organic synthesis, 4-Nitro-1H-indazole can undergo various functional group transformations, such as reduction or substitution reactions, to introduce different chemical moieties onto the indazole scaffold. This flexibility allows chemists to tailor the structure of the final compound for specific applications, such as drug development or materials science.Additionally, 4-Nitro-1H-indazole can act as a precursor for the synthesis of heterocyclic compounds, which are commonly found in natural products and pharmaceuticals. By manipulating the chemical structure of 4-Nitro-1H-indazole, chemists can access a wide variety of new compounds with potentially valuable properties.Overall, 4-Nitro-1H-indazole is a valuable tool in the arsenal of synthetic chemists, offering a versatile platform for the construction of complex molecules with diverse applications. Its role in chemical synthesis highlights its importance in driving innovation and discovery in the field of chemistry.

Literature

• N-(7-Eth-oxy-1H-indazol-4-yl)-4-methyl-benzene-sulfonamide.

  Acta crystallographica. Section E, Structure reports online 20110601

• Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation.

  Bioorganic & medicinal chemistry 20090901

• 4-substituted indazoles as new inhibitors of neuronal nitric oxide synthase.

  Bioorganic & medicinal chemistry letters 20070601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Regioisomeric 4-nitroindazole N1- and N2-(beta-D-ribonucleosides).

  Acta crystallographica. Section C, Crystal structure communications 20040101

• Regioselective synthesis of indazole N1- and N2-(beta-D-ribonucleosides).

  Nucleosides, nucleotides & nucleic acids 20040101