298-57-7 | Cinnarizine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$25.00	$17.00
5g	98%	in stock	$41.00	$29.00
10g	98%	in stock	$51.00	$36.00
25g	98%	in stock	$97.00	$68.00
50g	98%	in stock	$182.00	$127.00
100g	98%	in stock	$249.00	$175.00
500g	98%	in stock	$556.00	$390.00

Description

• Catalog Number: AI46759
• Chemical Name: Cinnarizine
• CAS Number: 298-57-7
• Molecular Formula: C26H28N2
• Molecular Weight: 368.51392000000004
• MDL Number: MFCD00056037
• SMILES: c1ccc(cc1)C=CCN1CCN(CC1)C(c1ccccc1)c1ccccc1
• NSC Number: 290687

Computed Properties

• Complexity: 429
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 28
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• XLogP3: 5.8

Literature

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  Toxicological sciences : an official journal of the Society of Toxicology 20131101

• Formulation and in vitro evaluation of self-emulsifying formulations of Cinnarizine.

  Drug development and industrial pharmacy 20121001

• Novel self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of cinnarizine: design, optimization, and in-vitro assessment.

  AAPS PharmSciTech 20120901

• Peculiarities of heart rhythm variability in narcotized and immobilized wakeful rats during blockade of calcium channels.

  Bulletin of experimental biology and medicine 20120901

• Is the amorphous fraction of a dried nanosuspension caused by milling or by drying? A case study with Naproxen and Cinnarizine.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801

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  Clinical drug investigation 20120601

• Efficacy and safety of cinnarizine in the prophylaxis of migraine headaches in children: an open, randomized comparative trial with propranolol.

  Acta neurologica Belgica 20120301

• A comparison of cinnarizine and transdermal scopolamine for the prevention of seasickness in naval crew: a double-blind, randomized, crossover study.

  Clinical neuropharmacology 20120101

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  The Journal of pharmacy and pharmacology 20111101

• Encapsulation of poorly soluble basic drugs into enteric microparticles: a novel approach to enhance their oral bioavailability.

  International journal of pharmaceutics 20110915

• The effects of cinnarizine on menopausal symptoms in women.

  Climacteric : the journal of the International Menopause Society 20110801

• Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration.

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  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100614

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  AAPS PharmSciTech 20100301

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  Proceedings of the National Academy of Sciences of the United States of America 20100223

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• Voltammetric oxidation and determination of cinnarizine at glassy carbon electrode modified with multi-walled carbon nanotubes.

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• Second-derivative synchronous fluorometric method for the simultaneous determination of cinnarizine and domperidone in pharmaceutical preparations. Application to biological fluids.

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• Second-derivative synchronous fluorescence spectroscopy for the simultaneous determination of cinnarizine and nicergoline in pharmaceutical preparations.

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• The effect of cinnarizine and cocculus indicus on simulator sickness.

  Physiology & behavior 20070516

• Development and characterization of floating microballoons for oral delivery of cinnarizine by a factorial design.

  Journal of microencapsulation 20070501

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  Neuroscience and behavioral physiology 20070301

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