-
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Toxicological sciences : an official journal of the Society of Toxicology 20131101
-
Formulation and in vitro evaluation of self-emulsifying formulations of Cinnarizine.
Drug development and industrial pharmacy 20121001
-
Novel self-nanoemulsifying drug delivery systems (SNEDDS) for oral delivery of cinnarizine: design, optimization, and in-vitro assessment.
AAPS PharmSciTech 20120901
-
Peculiarities of heart rhythm variability in narcotized and immobilized wakeful rats during blockade of calcium channels.
Bulletin of experimental biology and medicine 20120901
-
Is the amorphous fraction of a dried nanosuspension caused by milling or by drying? A case study with Naproxen and Cinnarizine.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801
-
Comparison of the therapeutic efficacy of a fixed low-dose combination of cinnarizine and dimenhydrinate with betahistine in vestibular neuritis: a randomized, double-blind, non-inferiority study.
Clinical drug investigation 20120601
-
Efficacy and safety of cinnarizine in the prophylaxis of migraine headaches in children: an open, randomized comparative trial with propranolol.
Acta neurologica Belgica 20120301
-
A comparison of cinnarizine and transdermal scopolamine for the prevention of seasickness in naval crew: a double-blind, randomized, crossover study.
Clinical neuropharmacology 20120101
-
Simultaneous determination of a novel diphenylpiperazine calcium channel blocker and its four metabolites in rat liver microsomes by liquid chromatography tandem mass spectrometry.
Pharmacology 20120101
-
[Vertigo in elderly patients. Early therapy chronification].
MMW Fortschritte der Medizin 20111117
-
Bead layering as a process to stabilize nanosuspensions: influence of drug hydrophobicity on nanocrystal reagglomeration following in-vitro release from sugar beads.
The Journal of pharmacy and pharmacology 20111101
-
Encapsulation of poorly soluble basic drugs into enteric microparticles: a novel approach to enhance their oral bioavailability.
International journal of pharmaceutics 20110915
-
The effects of cinnarizine on menopausal symptoms in women.
Climacteric : the journal of the International Menopause Society 20110801
-
Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration.
Journal of controlled release : official journal of the Controlled Release Society 20110730
-
Epley's manoeuvre versus Epley's manoeuvre plus labyrinthine sedative as management of benign paroxysmal positional vertigo: prospective, randomised study.
The Journal of laryngology and otology 20110601
-
No effects of anti-motion sickness drugs on vestibular evoked myogenic potentials outcome parameters.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20110401
-
Zebrafish (Danio rerio) embryos as a model for testing proteratogens.
Toxicology 20110315
-
Quantification of cyclizine and norcyclizine in human plasma by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110315
-
Comparison of cinnarizine/dimenhydrinate fixed combination with the respective monotherapies for vertigo of various origins: a randomized, double-blind, active-controlled, multicentre study.
Clinical drug investigation 20110101
-
Melanogenesis inhibitory activity of two generic drugs: cinnarizine and trazodone in mouse B16 melanoma cells.
International journal of molecular sciences 20110101
-
Precipitation of a poorly soluble model drug during in vitro lipolysis: characterization and dissolution of the precipitate.
Journal of pharmaceutical sciences 20101201
-
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Toxicological sciences : an official journal of the Society of Toxicology 20101201
-
[Vertigo. Evidence based therapy of dizziness].
MMW Fortschritte der Medizin 20101125
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
Biorelevant media simulating fed state intestinal fluids: colloid phase characterization and impact on solubilization capacity.
Journal of pharmaceutical sciences 20100801
-
Lipophilic cationic drugs increase the permeability of lysosomal membranes in a cell culture system.
Journal of cellular physiology 20100701
-
Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media.
The Journal of pharmacy and pharmacology 20100701
-
Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water-soluble drugs II. In-vivo evaluation.
The Journal of pharmacy and pharmacology 20100701
-
Effect of route of administration on the pharmacokinetics and toxicokinetics of cinnarizine in dogs.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100614
-
The differential diagnoses of parkinsonism: findings from a cohort of 1528 patients and a 10 years comparison in tertiary movement disorders clinics.
Clinical neurology and neurosurgery 20100601
-
Colloid formation by drugs in simulated intestinal fluid.
Journal of medicinal chemistry 20100527
-
Quantitative determination of pimozide in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study.
Journal of pharmaceutical and biomedical analysis 20100406
-
In vitro release kinetics and bioavailability of gastroretentive cinnarizine hydrochloride tablet.
AAPS PharmSciTech 20100301
-
A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle.
Proceedings of the National Academy of Sciences of the United States of America 20100223
-
Pharmacokinetics, tissue distribution and safety of cinnarizine delivered in lipid emulsion.
International journal of pharmaceutics 20100104
-
[Omaron in the restorative treatment of patients with chronic cerebrovascular insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
-
[Omaron in the rehabilitation of post stroke outpatients].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
-
[Omaron in the complex treatment of patients with multiple sclerosis].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
-
Pharmacological modulation of transmitter release by inhibition of pressure-dependent potassium currents in vestibular hair cells.
Naunyn-Schmiedeberg's archives of pharmacology 20091201
-
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Nature chemical biology 20091001
-
[Observation on therapeutic effect of He's Santong needling methods on cold erythema multiforme].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20091001
-
Improvement of oral bioavailability of flurbiprofen from flurbiprofen/beta-cyclodextrin inclusion complex by action of cinnarizine.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090901
-
Voltammetric oxidation and determination of cinnarizine at glassy carbon electrode modified with multi-walled carbon nanotubes.
Colloids and surfaces. B, Biointerfaces 20090901
-
Flunarizine and cinnarizine-induced parkinsonism: 25 years of de Melo-Souza's syndrome.
Arquivos de neuro-psiquiatria 20090901
-
In vitro gastrointestinal lipolysis of four formulations of piroxicam and cinnarizine with the self emulsifying excipients Labrasol and Gelucire 44/14.
Pharmaceutical research 20090801
-
Acute toxicity and toxicokinetics of dipfluzine hydrochloride, a novel calcium channel blocker.
Regulatory toxicology and pharmacology : RTP 20090601
-
Formulation, stability and degradation kinetics of intravenous cinnarizine lipid emulsion.
International journal of pharmaceutics 20090521
-
[Omaron in the treatment of vertebrobasilar insufficiency].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
-
[Use of omaron in patients with post-stroke cognitive disorders].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
-
[Parkinsonism due to the medication].
Nederlands tijdschrift voor geneeskunde 20090101
-
Repression of FasL expression by dipfluzine involves a mechanism of inhibition of NFATc transactivation.
Yao xue xue bao = Acta pharmaceutica Sinica 20081201
-
An evaluation of the relative roles of the unstirred water layer and receptor sink in limiting the in-vitro intestinal permeability of drug compounds of varying lipophilicity.
The Journal of pharmacy and pharmacology 20081001
-
Morphological assessment of the cerebroprotective action of lanthanum acetate in chronic cerebral ischemia in rats.
Neuroscience and behavioral physiology 20080901
-
In situ dissolution testing using potentiometric sensors.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807
-
Determination of mianserin in human plasma by high performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI/MS): application to a bioequivalence study in Chinese volunteers.
Journal of pharmaceutical and biomedical analysis 20080805
-
Cinnarizine in refractory migraine prophylaxis: efficacy and tolerability. A comparison with sodium valproate.
The journal of headache and pain 20080401
-
Prednisone treatment for vestibular neuritis.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20080401
-
Method development and validation for the simultaneous determination of cinnarizine and co-formulated drugs in pharmaceutical preparations by capillary electrophoresis.
Journal of pharmaceutical and biomedical analysis 20080213
-
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Journal of medicinal chemistry 20080124
-
Second-derivative synchronous fluorometric method for the simultaneous determination of cinnarizine and domperidone in pharmaceutical preparations. Application to biological fluids.
Journal of fluorescence 20080101
-
[In-vitro evaluation of cinnarizine as a competing agent to beta-cyclodextrin inclusion complexes: effect of cinnarizine on the membrane permeation rate of progesterone from its beta-cyclodextrin inclusion complex].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080101
-
A fixed combination of cinnarizine/dimenhydrinate for the treatment of patients with acute vertigo due to vestibular disorders : a randomized, reference-controlled clinical study.
Clinical drug investigation 20080101
-
Smart stability-indicating spectrophotometric methods for determination of binary mixtures without prior separation.
Journal of AOAC International 20080101
-
Second-derivative synchronous fluorescence spectroscopy for the simultaneous determination of cinnarizine and nicergoline in pharmaceutical preparations.
Journal of AOAC International 20080101
-
Treatment of vertebrobasilar insufficiency--associated vertigo with a fixed combination of cinnarizine and dimenhydrinate.
The international tinnitus journal 20080101
-
Multimodal therapy for chronic tinnitus.
The international tinnitus journal 20080101
-
[Phezam in combined therapy of ischemic stroke].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
-
A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats.
International journal of pharmaceutics 20070801
-
The effect of cinnarizine and cocculus indicus on simulator sickness.
Physiology & behavior 20070516
-
Development and characterization of floating microballoons for oral delivery of cinnarizine by a factorial design.
Journal of microencapsulation 20070501
-
Characteristics of the formation of chronic fatigue syndrome and approaches to its treatment in young patients with focal brain damage.
Neuroscience and behavioral physiology 20070301
-
Efficacy and tolerability of a fixed low-dose combination of cinnarizine and dimenhydrinate in the treatment of vertigo: a 4-week, randomized, double-blind, active- and placebo-controlled, parallel-group, outpatient study.
Clinical therapeutics 20070101
-
Optimizing the pharmacological component of integrated balance therapy.
Brazilian journal of otorhinolaryngology 20070101
-
[Efficacy of the pharmacotherapy of secondary enuresis in children].
Likars'ka sprava 20070101
-
High-performance liquid chromatographic assay for cinnarizine in human plasma.
Acta poloniae pharmaceutica 20070101
-
[Treatment costs of otogenic vertigo].
Medizinische Klinik (Munich, Germany : 1983) 20061115
-
Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach.
Journal of pharmaceutical sciences 20061001
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Pediatric cinnarizine overdose and toxicokinetics.
Pediatrics 20060501
-
[Calcium antagonists in the urethral syndrome of women with urinary incontinence and urgency].
Actas urologicas espanolas 20060401
-
Open-label trial of cinnarizine in migraine prophylaxis.
Headache 20060301
-
Effect of dipfluzine on delayed afterdepolarizations and triggered activity induced by isoprenaline in human atrial fibers.
Yao xue xue bao = Acta pharmaceutica Sinica 20060201
-
Tardive blepharospasm associated with cinnarizine use.
Clinical neuropharmacology 20060101
-
[Effects of dipfluzine on expressions of E-selectin, P-selectin, and ICAM-1 in brain ischemia-reperfusion rats].
Yao xue xue bao = Acta pharmaceutica Sinica 20051201
-
Effects of cinnarizine, a calcium antagonist that produces human parkinsonism, in parkin knock out mice.
Neuropharmacology 20050801
-
Cinnarizine has an atypical antipsychotic profile in animal models of psychosis.
Journal of psychopharmacology (Oxford, England) 20050701
-
Effects of cinnarizine on calcium and pressure-dependent potassium currents in guinea pig vestibular hair cells.
Naunyn-Schmiedeberg's archives of pharmacology 20050601
-
Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug.
Journal of pharmaceutical sciences 20050301
-
Mechanism of anti-apoptotic action of dipfluzine on neuronal damage of the rat hippocampal CA1 region subjected to transient forebrain ischemia.
Yao xue xue bao = Acta pharmaceutica Sinica 20050201
-
[Metabolic pathways of dipfluzine in rats].
Yao xue xue bao = Acta pharmaceutica Sinica 20050201
-
[Phezam efficacy in patients with chronic cerebral ischemic disease].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
-
[Iatrogenic neurological disorders in old people: a review].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20050101
-
Using a novel multicompartment dissolution system to predict the effect of gastric pH on the oral absorption of weak bases with poor intrinsic solubility.
Journal of pharmaceutical sciences 20050101
-
[Effect of fezam on ocular dynamics in patients with senile macular degeneration].
Vestnik oftalmologii 20050101
-
New methods for determination of cinnarizine in mixture with piracetam by spectrodensitometry, spectrophotometry, and liquid chromatography.
Journal of AOAC International 20050101
-
A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs.
Journal of controlled release : official journal of the Controlled Release Society 20040930
-
Parkinsonism and other movement disorders in outpatients in chronic use of cinnarizine and flunarizine.
Arquivos de neuro-psiquiatria 20040901
-
Flunarizine and cinnarizine-induced parkinsonism: a historical and clinical analysis.
Parkinsonism & related disorders 20040601
-
Inhibition of voltage-gated calcium currents in type II vestibular hair cells by cinnarizine.
Naunyn-Schmiedeberg's archives of pharmacology 20040601
-
Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study.
Clinical therapeutics 20040601
-
Hypnic headache: PSG evidence of both REM- and NREM-related attacks.
Neurology 20040427
-
Influence of an antivertiginous combination preparation of cinnarizine and dimenhydrinate on event-related potentials, reaction time and psychomotor performance--a randomized, double-blind, 3-way crossover study in healthy volunteers.
International journal of clinical pharmacology and therapeutics 20040401
-
Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations.
Pharmaceutical research 20040201
-
Drug solubilization behavior during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids.
Pharmaceutical research 20040201
-
[The influence of cinnarizine and alvityl on cerebral blood flow and high nervous activity in chronic cerebral ischemia model].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
-
[The influence of betaserk and cinarizine on vestibular function, highest nervous activity and brain circulation in chronic cerebral ischemia: a model study].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101
-
Tinnitus.
Clinical evidence 20030601
-
A randomized trial of the canalith repositioning procedure.
The Laryngoscope 20030501
-
Influence of 3 antivertiginous medications on the vigilance of healthy volunteers.
International journal of clinical pharmacology and therapeutics 20030401
-
Simultaneous determination of domperidone and cinnarizine in a binary mixture using derivative spectrophotometry, partial least squares and principle component regression calibration.
Analytical and bioanalytical chemistry 20030101
-
Cinnarizine is a useful and well-tolerated drug in the treatment of acquired cold urticaria (ACU).
European journal of dermatology : EJD 20030101
-
[The medical management of patients with neurological disturbances who had participated in the elimination of the effects of the Chernobyl accident].
Likars'ka sprava 20030101
-
[Comparative efficacy of betaserc and cinnarizine of vertigo in patients with migraine].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101
-
[Rehabilitative therapy of tinnitus and vertigo].
Recenti progressi in medicina 20030101
-
Cinnarizine in migraine prophylaxis: efficacy, tolerability and predictive factors for therapeutic responsiveness. An open-label pilot trial.
Functional neurology 20030101
-
[Effect of cinnarizine on the brain mitochondrial oxidative system, antioxidant blood activity, and the rat behavior in hypoxia].
Eksperimental'naia i klinicheskaia farmakologiia 20030101
-
[Current approaches to the treatment of vertigo in children].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101
-
Lichenoid eruption associated with cinnarizine use.
Pharmacy world & science : PWS 20021201
-
Effects of dipfluzine on delayed afterdepolarizations and triggered activity induced by ouabain in guinea pig papillary muscles.
Acta pharmacologica Sinica 20021001
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[Effect of dipfluzine on acute ischemic brain edema in gerbils].
Zhonghua yi xue za zhi 20020825
-
Simultaneous determination of domperidone maleate and cinnarizine in a binary mixture using derivative ratio spectrophotometry and classical least squares calibration.
Journal of pharmaceutical and biomedical analysis 20020822
-
Central effects of cinnarizine: restricted use in aircrew.
Aviation, space, and environmental medicine 20020601
-
LC and TLC determination of cinnarizine in pharmaceutical preparations and serum.
Journal of pharmaceutical and biomedical analysis 20020515
-
New approaches to the management of peripheral vertigo: efficacy and safety of two calcium antagonists in a 12-week, multinational, double-blind study.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 20020501
-
Application of 1,3-dibromo-5,5-dimethylhydantoin (DBH) instead of bromine gas or bromine water decolorization for drug identification according to PH. EUR. Analytical methods of pharmacopoeias with DBH in respect to environmental and economical concern, Part 14.
Die Pharmazie 20020501
-
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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Simple spectrophotometric determination of cinnarizine in its dosage forms.
Farmaco (Societa chimica italiana : 1989) 20020401
-
Report of eight new cases of hypnic headache and mini-review of the literature.
Functional neurology 20020101
-
Fixed combination of cinnarizine and dimenhydrinate versus betahistine dimesylate in the treatment of Ménière's disease: a randomized, double-blind, parallel group clinical study.
The international tinnitus journal 20020101
-
Characterization of voltage-gated calcium currents in freshly isolated smooth muscle cells from rat tail main artery.
Acta physiologica Scandinavica 20011101
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The effects of dimenhydrinate, cinnarizine and transdermal scopolamine on performance.
Journal of psychopharmacology (Oxford, England) 20010901
-
Effect of dipfluzine on L-type calcium current in guinea pig ventricular myocytes.
Acta pharmacologica Sinica 20010801
-
Functional overlap of IP(3)- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons.
American journal of physiology. Gastrointestinal and liver physiology 20010701
-
Quantitative prediction of catalepsy induced by amoxapine, cinnarizine and cyclophosphamide in mice.
Biopharmaceutics & drug disposition 20000501
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[Akathisia, parkinsonism and depression induced by cinnarizine: a case report].
Revista de neurologia 19990501
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Cinnarizine-induced cholestasis.
Journal of hepatology 19990301
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[Drug-induced parkinsonism. Clinical aspects compared with Parkinson disease].
Revista de neurologia 19980701
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Etiology of parkinsonism in a Brazilian movement disorders clinic.
Arquivos de neuro-psiquiatria 19980601
-
Cinnarizine-induced parkinsonism: ten years later.
Movement disorders : official journal of the Movement Disorder Society 19980501
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Subacute cutaneous lupus erythematosus associated with cinnarizine and thiethylperazine therapy.
Lupus 19980101
-
A long-term follow-up study of cinnarizine- and flunarizine-induced parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 19970101
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[The relationship between anticonvulsant and anti-anxiety effects of calcium channel blockers].
Eksperimental'naia i klinicheskaia farmakologiia 19970101
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Possible pharmacokinetic and pharmacodynamic factors affecting parkinsonism inducement by cinnarizine and flunarizine.
Biochemical pharmacology 19951109
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Effects of the combination of ketoconazole and calcium channel antagonists against Candida albicans in vitro.
Arzneimittel-Forschung 19930701
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Cinnarizine-induced parkinsonism in primates.
Clinical neuropharmacology 19920401
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Calcium-entry blockers-induced parkinsonism: possible role of inherited susceptibility.
Neurotoxicology 19920101
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Cholestasis associated with cinnarizine.
BMJ (Clinical research ed.) 19901201
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Extrapyramidal and depressive side reactions with flunarizine and cinarizine.
Journal of neurology, neurosurgery, and psychiatry 19890201
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Movement disorders and depression due to flunarizine and cinnarizine.
Movement disorders : official journal of the Movement Disorder Society 19890101
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Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine.
BMJ (Clinical research ed.) 19880917
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Cardiovascular and renal actions of calcium channel blocker chemical subgroups: a search for renal specificity.
The Journal of pharmacy and pharmacology 19880601
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Aggravation of Parkinson's disease by cinnarizine.
Journal of neurology, neurosurgery, and psychiatry 19880101
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Flunarizine- and cinnarizine-induced extrapyramidal reactions.
Neurology 19870501
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Parkinsonism, tardive dyskinesia, akathisia, and depression induced by flunarizine.
Lancet (London, England) 19860802
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Parkinsonism, tardive dyskinesia, akathisia, and depression induced by flunarizine.
Lancet (London, England) 19860607
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Flunarizine in common migraine: Italian cooperative trial. II. Long-term follow-up.
Cephalalgia : an international journal of headache 19850501
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Protective effect of creatinol O-phosphate (COP) on ventricular fibrillation and death induced by intravenous CaCl2 in mice.
Arzneimittel-Forschung 19790101
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Anticonvulsive properties of cinnarizine and flunarizine in rats and mice.
Arzneimittel-Forschung 19750901
