2999-46-4 | Ethyl isocyanoacetate

Packsize	Purity	Availability	Price	Discounted Price
1g	98%(GC)	in stock	$47.00	$33.00
5g	>97.0%(GC)	in stock	$93.00	$65.00
25g	>97.0%(GC)	in stock	$318.00	$222.00

Description

• Catalog Number: AI46837
• Chemical Name: Ethyl isocyanoacetate
• CAS Number: 2999-46-4
• Molecular Formula: C5H7NO2
• Molecular Weight: 113.1146
• MDL Number: MFCD00000007
• SMILES: [C-]#[N+]CC(=O)OCC

Computed Properties

• Complexity: 122
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• XLogP3: 0.4

Literature

• Reactions of β-alkoxyvinyl polyfluoroalkyl ketones with ethyl isocyanoacetate and its use for the synthesis of new polyfluoroalkyl pyrroles and pyrrolidines.

  Organic & biomolecular chemistry 20121128

• Multiple tyrosine metabolites are GPR35 agonists.

  Scientific reports 20120101

• Double isocyanide cyclization: a synthetic strategy for two-carbon-tethered pyrrole/oxazole pairs.

  Journal of the American Chemical Society 20110216

• Ethyl 1-formamido-4-oxo-2,6-diphenyl-cyclo-hexa-necarboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20110201

• Tandem Michael addition/intramolecular isocyanide [3 + 2] cycloaddition: highly diastereoselective one pot synthesis of fused oxazolines.

  Chemical communications (Cambridge, England) 20100521

• Porphyrin on a half-shell! Synthesis and characterization of corannulenoporphyrins.

  The Journal of organic chemistry 20100416

• Assembly of indole-2-carboxylic acid esters through a ligand-free copper-catalysed cascade process.

  Chemical communications (Cambridge, England) 20091228

• Tandem double-Michael-addition/cyclization/acyl migration of 1,4-dien-3-ones and ethyl isocyanoacetate: stereoselective synthesis of pyrrolizidines.

  Angewandte Chemie (International ed. in English) 20090101

• Dipolar cycloaddition of ethyl isocyanoacetate to 3-chloro-2-(methylthio)/2-(methylsulfonyl)quinoxalines: highly regio- and chemoselective synthesis of substituted imidazo[1,5-a]quinoxaline-3-carboxylates.

  The Journal of organic chemistry 20070622

• Synthesis of bis-armed amino acid derivatives via the alkylation of ethyl isocyanoacetate and the Suzuki-Miyaura cross-coupling reaction.

  Amino acids 20070101

• Aroylketene dithioacetal chemistry: facile synthesis of 4-aroyl-3-methylsulfanyl-2-tosylpyrroles from aroylketene dithioacetals and TosMIC.

  Beilstein journal of organic chemistry 20070101

• Synthesis and modification of dibenzylglycine derivatives via the Suzuki-Miyaura cross-coupling reaction.

  The journal of peptide research : official journal of the American Peptide Society 20040801

• The building block approach to unusual alpha-amino acid derivatives and peptides.

  Accounts of chemical research 20030501

• First and unexpected synthesis of macrocyclic cyclophane-based unusual alpha-amino acid derivatives by phosphazene base without high dilution conditions.

  Bioorganic & medicinal chemistry letters 20020408

• Synthesis of highly functionalised dibenzylglycine derivatives via the Suzuki-Miyaura coupling reaction.

  Bioorganic & medicinal chemistry letters 20020107

• Vinyl sulfones in solid-phase synthesis: preparation of 4,5,6,7-tetrahydroisoindole derivatives.

  The Journal of organic chemistry 20010810