30299-08-2 | Clinofibrate

Packsize	Purity	Availability	Price	Discounted Price
1mg	97%	in stock	$6.00	$4.00
5mg	97%	in stock	$7.00	$5.00
10mg	97%	in stock	$9.00	$6.00
50mg	97%	in stock	$11.00	$8.00
1g	97%	in stock	$203.00	$142.00
5g	97%	in stock	$573.00	$402.00
10g	97%	in stock	$946.00	$662.00

Description

• Catalog Number: AB39181
• Chemical Name: Clinofibrate
• CAS Number: 30299-08-2
• Molecular Formula: C28H36O6
• Molecular Weight: 468.5818
• MDL Number: MFCD00865769
• SMILES: CCC(C(=O)O)(Oc1ccc(cc1)C1(CCCCC1)c1ccc(cc1)OC(C(=O)O)(CC)C)C

Computed Properties

• Complexity: 633
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 34
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 10
• Undefined Atom Stereocenter Count: 2
• XLogP3: 7.5

Literature

• In vitro evaluation of inhibitory effects of antidiabetic and antihyperlipidemic drugs on human carboxylesterase activities.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• 4,4'-(Cyclo-hexane-1,1-di-yl)diphenol methanol solvate.

  Acta crystallographica. Section E, Structure reports online 20090201

• Flow cytometric evaluation of synergistic pro-apoptotic effects of statins and clofibrates in IM-9 human lymphoblasts.

  Clinical and experimental pharmacology & physiology 20070901

• A case of familial hypercholesterolemia; secession from LDL-apheresis by the drug treatment with potent statin and resin.

  The Tokai journal of experimental and clinical medicine 20050901

• [Usefulness of examination of the cholesterol versus triglyceride ratio for lipoprotein fractions in a patient with marked hyper-triglyceridemia].

  Rinsho byori. The Japanese journal of clinical pathology 20021001

• Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.

  Biochemical and biophysical research communications 20020111

• Effects of some hypolipidemic agents on biochemical values and hepatic peroxisomal enzymes in rats: comparison of probucol, CGA, KCD-232, MLM-160, AL-369 and clinofibrate with clofibrate.

  Journal of pharmacobio-dynamics 19870301