3034-53-5 | 2-Bromothiazole

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$12.00	$8.00
100g	98%	in stock	$22.00	$15.00

Description

• Catalog Number: AB39525
• Chemical Name: 2-Bromothiazole
• CAS Number: 3034-53-5
• Molecular Formula: C3H2BrNS
• Molecular Weight: 164.0237
• MDL Number: MFCD00005316
• SMILES: Brc1nccs1
• NSC Number: 91532

Computed Properties

• Complexity: 50.1
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 1.8

Upstream Synthesis Route

2-Bromothiazole is a vital building block in chemical synthesis, particularly in the pharmaceutical and agrochemical industries. This compound serves as a versatile intermediate, playing a crucial role in the development of various pharmaceuticals, herbicides, and insecticides. Its unique structure and reactivity make it an essential component in the creation of complex molecules with diverse biological activities. By strategically incorporating 2-Bromothiazole into synthetic pathways, chemists can access novel compounds that exhibit potential therapeutic or agronomic properties. Additionally, its compatibility with a wide range of functional groups enables the efficient modification and optimization of molecular structures to enhance desired properties. Through strategic utilization in chemical synthesis, 2-Bromothiazole facilitates the creation of innovative compounds with promising applications in medicine and agriculture.

Literature

• Regioselective functionalization of the thiazole scaffold using TMPMgCl·LiCl and TMP2Zn·2MgCl2·2LiCl.

  The Journal of organic chemistry 20110819

• Synthesis and characterization of fused pyrrolo[3,2-d:4,5-d']bisthiazole-containing polymers.

  Organic letters 20101203

• Synthesis and biological activity of N-aryl-2-aminothiazoles: potent pan inhibitors of cyclin-dependent kinases.

  Bioorganic & medicinal chemistry letters 20040607

• Use of thiazoles in the halogen dance reaction: application to the total synthesis of WS75624 B.

  The Journal of organic chemistry 20040402