307538-42-7 | Smer28

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%	in stock	$63.00	$45.00
10mg	98%	in stock	$119.00	$83.00
50mg	98%	in stock	$490.00	$343.00
100mg	98%	in stock	$915.00	$640.00

Description

• Catalog Number: AB41288
• Chemical Name: Smer28
• CAS Number: 307538-42-7
• Molecular Formula: C11H10BrN3
• Molecular Weight: 264.1212
• MDL Number: MFCD02166825
• SMILES: C=CCNc1ncnc2c1cc(Br)cc2

Computed Properties

• Complexity: 222
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.2

Literature

• Structural characterization and high-throughput screening of inhibitors of PvdQ, an NTN hydrolase involved in pyoverdine synthesis.

  ACS chemical biology 20111118

• A small-molecule enhancer of autophagy decreases levels of Abeta and APP-CTF via Atg5-dependent autophagy pathway.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110601

• Potent inhibitors of Huntingtin protein aggregation in a cell-based assay.

  Bioorganic & medicinal chemistry letters 20090315

• Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

  Nature chemical biology 20070601

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Contact dermatitis from proprietary preparations in Malaysia.

  International journal of dermatology 19760101