30924-93-7 | L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl) ester

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$10.00	$7.00
5g	98%	in stock	$16.00	$11.00
10g	98%	in stock	$23.00	$16.00
25g	98%	in stock	$43.00	$30.00

Description

• Catalog Number: AB41918
• Chemical Name: L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-(phenylmethyl) ester
• CAS Number: 30924-93-7
• Molecular Formula: C17H23NO6
• Molecular Weight: 337.3676
• MDL Number: MFCD00065568
• SMILES: OC(=O)CC[C@@H](C(=O)OCc1ccccc1)NC(=O)OC(C)(C)C

Computed Properties

• Complexity: 437
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 10
• XLogP3: 2.2

Upstream Synthesis Route

N-tert-Butoxycarbonyl-L-glutamic acid benzyl ester, also known as Boc-Glu(OBzl)-OH, is a valuable compound widely used in chemical synthesis. As a protected form of glutamic acid, this compound plays a crucial role in peptide synthesis and drug development. With its tert-butoxycarbonyl (Boc) protecting group and benzyl ester, N-tert-Butoxycarbonyl-L-glutamic acid benzyl ester offers strategic versatility in building complex peptide structures. Its stability and compatibility with various chemical reactions make it an essential building block for designing novel peptides and peptidomimetics with targeted biological activities. In addition, the selective deprotection of the Boc group allows for further functionalization, enabling tailored modifications to achieve desired molecular properties. This compound is a valuable tool for chemists seeking to advance their research in the fields of medicinal chemistry, biochemistry, and pharmaceuticals.

Literature

• Epsilon substituted lysinol derivatives as HIV-1 protease inhibitors.

  Bioorganic & medicinal chemistry letters 20100715

• Modification of the vitamin K-dependent carboxylase assay.

  Journal of biochemical and biophysical methods 19850501