3107-33-3 | 3-(Trifluoromethyl)phenylhydrazine, HCl

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$6.00	$4.00
5g	97%	in stock	$8.00	$6.00
25g	97%	in stock	$29.00	$20.00
100g	97%	in stock	$96.00	$68.00

Description

• Catalog Number: AB42437
• Chemical Name: 3-(Trifluoromethyl)phenylhydrazine, HCl
• CAS Number: 3107-33-3
• Molecular Formula: C7H8ClF3N2
• Molecular Weight: 212.6000
• MDL Number: MFCD00100503
• SMILES: NNc1cccc(c1)C(F)(F)F.Cl
• NSC Number: 269918

Computed Properties

• Complexity: 146
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

3-(Trifluoromethyl)phenylhydrazine hydrochloride is a versatile chemical reagent commonly used in organic synthesis. Its unique trifluoromethyl group imparts significant chemical reactivity, making it valuable for various transformations in the laboratory.This compound serves as a valuable building block for introducing the trifluoromethyl group into organic molecules, a modification that can greatly enhance the biological activity or physical properties of the target compounds. The trifluoromethyl group is known for its lipophilicity and electron-withdrawing properties, which can lead to improved drug potency, metabolic stability, and bioavailability.In addition, 3-(Trifluoromethyl)phenylhydrazine hydrochloride can participate in various synthetic reactions such as nucleophilic substitution, condensation, and cross-coupling reactions. Its hydrazine moiety can act as a nucleophile towards electrophilic carbonyl compounds, enabling the formation of hydrazones or semicarbazones, which are valuable intermediates in organic synthesis.Furthermore, this compound can be utilized in the preparation of heterocyclic compounds, such as pyrazoles and pyridazines, which are important structural motifs found in many pharmaceuticals and agrochemicals. Its ability to introduce the trifluoromethyl group in these heterocyclic frameworks can lead to the development of novel bioactive molecules with enhanced properties.Overall, 3-(Trifluoromethyl)phenylhydrazine hydrochloride is a valuable tool in the hands of synthetic chemists for the efficient construction of complex organic molecules with diverse applications in medicinal chemistry, material science, and agrochemical research.