312-73-2 | 2-(Trifluoromethyl)benzimidazole

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$15.00	$10.00
1g	95%	in stock	$15.00	$11.00
10g	95%	in stock	$17.00	$12.00
25g	95%	in stock	$40.00	$28.00

Description

• Catalog Number: AI47188
• Chemical Name: 2-(Trifluoromethyl)benzimidazole
• CAS Number: 312-73-2
• Molecular Formula: C8H5F3N2
• Molecular Weight: 186.13390959999998
• MDL Number: MFCD00022675
• SMILES: FC(c1nc2c([nH]1)cccc2)(F)F

Computed Properties

• Complexity: 192
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.7

Literature

• Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives.

  European journal of medicinal chemistry 20120601

• Bis(2-trifluoro-methyl-1H-benzimidazol-3-ium) tetra-chloridomercurate dihydrate.

  Acta crystallographica. Section E, Structure reports online 20120601

• 2-Trifluoro-methyl-1H-benzimidazole.

  Acta crystallographica. Section E, Structure reports online 20120501

• 2-Trifluoro-methyl-1H-benzimidazol-3-ium nitrate.

  Acta crystallographica. Section E, Structure reports online 20120401

• 2-Trifluoro-methyl-1H-benzimidazol-3-ium tetra-fluoro-borate-2-trifluoro-methyl-1H-benzimidazole-water (1/1/1).

  Acta crystallographica. Section E, Structure reports online 20120401

• Bis(2-trifluoro-methyl-1H-benzimidazol-3-ium) naphthalene-1,5-disulfonate.

  Acta crystallographica. Section E, Structure reports online 20120201

• 2-Trifluoro-methyl-1H-benzimidazol-3-ium hydrogen sulfate.

  Acta crystallographica. Section E, Structure reports online 20111201

• 2-Trifluoro-methyl-1H-benzimidazol-3-ium perchlorate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Synthesis and biological activity of 2-(trifluoromethyl)-1H-benzimidazole derivatives against some protozoa and Trichinella spiralis.

  European journal of medicinal chemistry 20100701

• The old and new therapeutic approaches to the treatment of giardiasis: where are we?

  Biologics : targets & therapy 20090101

• Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study.

  Bioorganic & medicinal chemistry 20070115

• [Effect of benzimidazole and its derivatives on electrical activity of Helix albescens Rossm neurons and behavior of rats].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20070101

• Synthesis and antiprotozoal activity of some 2-(trifluoromethyl)-1H-benzimidazole bioisosteres.

  European journal of medicinal chemistry 20060101

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Synthesis and antiparasitic activity of 2-(trifluoromethyl)-benzimidazole derivatives.

  Bioorganic & medicinal chemistry letters 20010122