3128-29-8 | 3-Pyridinecarboxamide,1,4-dihydro-n-methyl-4-oxo-

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$572.00	$400.00
1g	95%	in stock	$1,395.00	$977.00

Description

• Catalog Number: AB76313
• Chemical Name: 3-Pyridinecarboxamide,1,4-dihydro-n-methyl-4-oxo-
• CAS Number: 3128-29-8
• Molecular Formula: C7H8N2O2
• Molecular Weight: 152.1506
• MDL Number: MFCD26132040
• SMILES: CNC(=O)c1c[nH]ccc1=O

Computed Properties

• Complexity: 253
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.2

Literature

• Distribution of purine nucleotides in uremic fluids and tissues.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100901

• Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry.

  Molecular bioSystems 20100501

• Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes.

  Molecular bioSystems 20100501

• Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption.

  Analytical chemistry 20100215

• Nicotinamide metabolites accumulate in the tissues of uremic rats.

  Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101

• Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation.

  International journal of clinical pharmacology and therapeutics 20070801

• Relationship between uremic toxins and oxidative stress in patients with chronic renal failure.

  Scandinavian journal of urology and nephrology 20070101

• Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis.

  BMC bioinformatics 20070101

• Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure.

  Pediatric nephrology (Berlin, Germany) 20060601

• Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20060201

• Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.

  Archives of toxicology 20050401

• Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101

• Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography.

  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

• Identification of N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-5-carboxamide as components in urine extracts of individuals consuming coffee.

  Journal of pharmaceutical and biomedical analysis 20021015