31448-54-1 | 2'-C-Methyluridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$17.00	$12.00
1g	97%	in stock	$29.00	$20.00
5g	97%	in stock	$55.00	$38.00
10g	97%	in stock	$83.00	$58.00
25g	97%	in stock	$205.00	$143.00
100g	97%	in stock	$782.00	$547.00

Description

• Catalog Number: AB51215
• Chemical Name: 2'-C-Methyluridine
• CAS Number: 31448-54-1
• Molecular Formula: C10H14N2O6
• Molecular Weight: 258.228
• MDL Number: MFCD02682960
• SMILES: OC[C@H]1O[C@H]([C@]([C@@H]1O)(C)O)n1ccc(=O)[nH]c1=O

Computed Properties

• Complexity: 411
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2
• XLogP3: -2.1

Literature

• Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors.

  Bioorganic & medicinal chemistry letters 20120615

• Practical synthesis of (2'R)-2'-deoxy-2'-C-methyluridine by highly diastereoselective homogeneous hydrogenation.

  The Journal of organic chemistry 20110107

• 10-23 DNAzyme modified with (2'R)- and (2'S)-2'-deoxy-2'-C-methyluridine in the catalytic core.

  Bioorganic & medicinal chemistry letters 20100801

• 2-C-methyluridine modified hammerhead ribozyme against the estrogen receptor.

  Bioorganic & medicinal chemistry letters 20100501

• DNAzymes and ribozymes carrying 2'-C-methyl nucleotides.

  Nucleic acids symposium series (2004) 20080101

• Activity and stability of hammerhead ribozymes containing 2'-C-methyluridine: a new RNA mimic.

  Chemistry & biodiversity 20050201