315703-52-7 | JK184

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$14.00	$10.00
5mg	95%	in stock	$26.00	$18.00
10mg	95%	in stock	$35.00	$25.00
25mg	95%	in stock	$54.00	$38.00
50mg	95%	in stock	$89.00	$63.00

Description

• Catalog Number: AF82544
• Chemical Name: JK184
• CAS Number: 315703-52-7
• Molecular Formula: C19H18N4OS
• Molecular Weight: 350.4374
• MDL Number: MFCD01044465
• SMILES: CCOc1ccc(cc1)Nc1scc(n1)c1c(C)nc2n1cccc2

Computed Properties

• Complexity: 432
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 25
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 5.1

Literature

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• The imidazopyridine derivative JK184 reveals dual roles for microtubules in Hedgehog signaling.

  Angewandte Chemie (International ed. in English) 20090101

• A small-molecule antagonist of the hedgehog signaling pathway.

  Chembiochem : a European journal of chemical biology 20071105