320-67-2 | 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$13.00	$9.00
1g	97%	in stock	$20.00	$14.00
5g	97%	in stock	$65.00	$45.00
10g	97%	in stock	$98.00	$69.00
25g	97%	in stock	$155.00	$108.00
100g	97%	in stock	$578.00	$405.00

Description

• Catalog Number: AB50212
• Chemical Name: 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydro-1,3,5-triazin-2-one
• CAS Number: 320-67-2
• Molecular Formula: C8H12N4O5
• Molecular Weight: 244.20467999999997
• MDL Number: MFCD00006539
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc(nc1=O)N
• NSC Number: 758186

Computed Properties

• Complexity: 384
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2
• XLogP3: -2.2

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  Blood 20120503

• Promoter hypermethylation of DNA damage response genes in hepatocellular carcinoma.

  Cell biology international 20120501

• Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501

• Epigenetic regulation of nuclear PI-PLCbeta1 signaling pathway in low-risk MDS patients during azacitidine treatment.

  Leukemia 20120501

• Safety, efficacy and biological predictors of response to sequential azacitidine and lenalidomide for elderly patients with acute myeloid leukemia.

  Leukemia 20120501

• DNMT3A mutations and response to the hypomethylating agent decitabine in acute myeloid leukemia.

  Leukemia 20120501

• Proteomic analysis identifies differentially expressed proteins in AML1/ETO acute myeloid leukemia cells treated with DNMT inhibitors azacitidine and decitabine.

  Leukemia research 20120501

• Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling.

  International journal of oncology 20120501

• Achieving a cure for HIV infection: do we have reasons to be optimistic?

  The Journal of antimicrobial chemotherapy 20120501

• Commentary on paper: 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene (Chachadi et al.).

  The international journal of biochemistry & cell biology 20120501

• Can soy phytoestrogens decrease DNA methylation in BRCA1 and BRCA2 oncosuppressor genes in breast cancer?

  Omics : a journal of integrative biology 20120501

• Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma.

  Upsala journal of medical sciences 20120501

• Decitabine and vorinostat cooperate to sensitize colon carcinoma cells to Fas ligand-induced apoptosis in vitro and tumor suppression in vivo.

  Journal of immunology (Baltimore, Md. : 1950) 20120501

• Epigenetic regulation of reelin and brain-derived neurotrophic factor genes in long-term potentiation in rat medial prefrontal cortex.

  Neurobiology of learning and memory 20120501

• Activation and epigenetic regulation of DNA transposon nDart1 in rice.

  Plant & cell physiology 20120501

• Epigenetic resensitization to platinum in ovarian cancer.

  Cancer research 20120501

• 5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.

  Future medicinal chemistry 20120501

• [Dynamic changes of gene expression profiles during cardiomyogenesis of human marrow mesenchymal stem cells].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120501

• [Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and methylation of CHFR in human laryngreal carcinoma cell line].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20120501

• The differentiating and apoptotic effects of 2-aza-5'-deoxycytidine are dependent on the PU.1 expression level in PU.1-transgenic K562 cells.

  Biochemical and biophysical research communications 20120420

• [A case report of undifferentiated connective tissue disease associated myelodysplastic].

  Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20120418

• NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity.

  British journal of cancer 20120410

• Identification of methylation-dependent regulatory elements for intergenic miRNAs in human H4 cells.

  Biochemical and biophysical research communications 20120406

• Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).

  Blood 20120405

• Azacitidine after allo-SCT: the good without the bad?

  Blood 20120405

• Epigenetic repression of regulator of G-protein signaling 2 promotes androgen-independent prostate cancer cell growth.

  International journal of cancer 20120401

• Interest of the association azacitidine-lenalidomide as frontline therapy in high-risk myelodysplasia or acute myeloid leukemia with complex karyotype.

  Leukemia 20120401

• Eosinophilic pneumonia associated with azacitidine in a patient with myelodysplastic syndrome.

  Respiratory care 20120401

• MicroRNA regulation via DNA methylation during the morula to blastocyst transition in mice.

  Molecular human reproduction 20120401

• AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401

• Hypermethylation of Sox17 gene is useful as a molecular diagnostic application in early gastric cancer.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401

• DNA methylation contributes to the regulation of sclerostin expression in human osteocytes.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20120401

• Does addition of erythropoiesis stimulating agents improve the outcome of higher-risk myelodysplastic syndromes treated with azacitidine?

  Leukemia research 20120401

• Azacitidine in a patient with newly diagnosed acute myeloid leukemia and poor risk cytogenetics: outcomes of prolonged therapy.

  Leukemia research 20120401

• Hypomethylating therapy and autoimmunity in MDS: an enigmatic relationship.

  Leukemia research 20120401

• Suppression of Klotho expression by protein-bound uremic toxins is associated with increased DNA methyltransferase expression and DNA hypermethylation.

  Kidney international 20120401

• Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells.

  Oncology reports 20120401

• Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells.

  Oncology reports 20120401

• SFRP1 promoter methylation and expression in human trabecular meshwork cells.

  Experimental eye research 20120401

• Diagnostic and prognostic utility of methylation and protein expression patterns of myopodin in colon cancer.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401

• Discovery of drugs that possess activity against feline leukemia virus.

  The Journal of general virology 20120401

• Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1.

  Antimicrobial agents and chemotherapy 20120401

• DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs.

  Biochemical pharmacology 20120401

• AZA-ESA combo: a new standard for higher risk MDS?

  Leukemia research 20120401

• Human first-trimester chorionic villi have a myogenic potential.

  Cell and tissue research 20120401

• Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.

  American journal of hematology 20120401

• The efficiency of in vitro isolation and myogenic differentiation of MSCs derived from adipose connective tissue, bone marrow, and skeletal muscle tissue.

  In vitro cellular & developmental biology. Animal 20120401

• A simple method for high-throughput quantification of genome-wide DNA methylation by fluorescence polarization.

  Epigenetics 20120401

• Promoter methylation regulates cigarette smoke-stimulated cyclooxygenase-2 expression in esophageal squamous cell carcinoma.

  Journal of digestive diseases 20120401

• When should iron chelation therapy be considered in patients with myelodysplasia and other bone marrow failure syndromes with iron overload?

  Internal medicine journal 20120401

• BCL2L10 is a predictive factor for resistance to azacitidine in MDS and AML patients.

  Oncotarget 20120401

• Epigenetic tailoring for the production of anti-infective cytosporones from the marine fungus Leucostoma persoonii.

  Marine drugs 20120401

• Reactivation of Silenced WT1 Transgene by Hypomethylating Agents - Implications for in vitro Modeling of Chemoimmunotherapy.

  Immune network 20120401

• DNA methylation-associated silencing of tumor-suppressor microRNAs in cancer.

  Oncogene 20120329

• Using peripheral blood circulating DNAs to detect CpG global methylation status and genetic mutations in patients with myelodysplastic syndrome.

  Biochemical and biophysical research communications 20120323

• Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells.

  Cancer cell 20120320

• Identification of the A kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma.

  Journal of surgical oncology 20120315

• Oligoamine analogues in combination with 2-difluoromethylornithine synergistically induce re-expression of aberrantly silenced tumour-suppressor genes.

  The Biochemical journal 20120315

• Genome-wide miRNA expression profiling identifies miR-9-3 and miR-193a as targets for DNA methylation in non-small cell lung cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120315

• Interstitial lung disease associated with azacitidine use: a case report.

  American journal of therapeutics 20120301

• Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.

  Head & neck 20120301

• The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.

  International journal of cancer 20120301

• Feasibility of hypomethylating agents followed by allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome.

  Bone marrow transplantation 20120301

• Aberrant methylation of RASSF2A in human pancreatic ductal adenocarcinoma and its relation to clinicopathologic features.

  Pancreas 20120301

• A case of Sweet's syndrome due to 5-Azacytidine and vorinostat in a patient with NK/T cell lymphoma.

  Cutaneous and ocular toxicology 20120301

• Azacitidine for treatment of imminent relapse in MDS or AML patients after allogeneic HSCT: results of the RELAZA trial.

  Leukemia 20120301

• How to manage lower-risk myelodysplastic syndromes.

  Leukemia 20120301

• Pilot study on combination of azacitidine and low-dose cytarabine for patients with refractory anemia with excess blast.

  Annals of hematology 20120301

• Down-regulation of CXCL12 by DNA hypermethylation and its involvement in gastric cancer metastatic progression.

  Digestive diseases and sciences 20120301

• A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy.

  Haematologica 20120301

• DNA demethylation by 5-aza-2-deoxycytidine treatment abrogates 17 beta-estradiol-induced cell growth and restores expression of DNA repair genes in human breast cancer cells.

  Cancer letters 20120301

• Pharmacological genome demethylation increases radiosensitivity of head and neck squamous carcinoma cells.

  International journal of molecular medicine 20120301

• MDS: Refining existing therapy through improved biologic insights.

  Blood reviews 20120301

• Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi.

  European journal of immunology 20120301

• Demethylation of the FCER1G promoter leads to FcεRI overexpression on monocytes of patients with atopic dermatitis.

  Allergy 20120301

• Atraumatic splenic rupture in patients with myelodysplastic syndromes: report of a case occurred during treatment with 5-azacitidine and review of the literature.

  Leukemia research 20120301

• RUNX3 is involved in caspase-3-dependent apoptosis induced by a combination of 5-aza-CdR and TSA in leukaemia cell lines.

  Journal of cancer research and clinical oncology 20120301

• Dynamic CpG-DNA methylation of Il10 and Il19 in CD4+ T lymphocytes and macrophages: effects on tissue-specific gene expression.

  Klinische Padiatrie 20120301

• Diversification of hAT transposase paralogues in the sugarcane genome.

  Molecular genetics and genomics : MGG 20120301

• Optimizing hypomethylating agents in myelodysplastic syndromes.

  Current opinion in hematology 20120301

• Increased proliferation and chemosensitivity of human mesenchymal stromal cells expressing fusion yeast cytosine deaminase.

  Stem cell research 20120301

• 5-Aza-2'-deoxycytidine increases the sensitivity of human bone marrow mesenchymal stem cells to chemotherapeutic agents by demethylation of p73.

  Journal of pediatric hematology/oncology 20120301

• Decitabine for acute myeloid leukemia.

  Expert review of anticancer therapy 20120301

• Antiproliferative and antitumor effects of azacitidine against the human myelodysplastic syndrome cell line SKM-1.

  Anticancer research 20120301

• [Effect of methylation inhibitor on EphB4 gene expression, proliferation and apoptosis in CEM cells].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20120301

• Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5a.

  PLoS genetics 20120301

• [Therapeutic effect of in vitro 5-aza-2'-deoxycytidine combined with imatinib on gastrointestinal stromal tumor].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120301

• Gene reactivation by 5-aza-2'-deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions.

  PLoS genetics 20120301

• [Cost-effectiveness analysis of azacitidine for myelodysplastic syndromes in Japan].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20120301

• [Effect of nesprin-1 in the differentiation of mouse embryonic stem cells into cardiomyocytes].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20120301

• Position effect variegation and epigenetic modification of a transgene in a pig model.

  Genetics and molecular research : GMR 20120216

• Azacitidine for the treatment of patients with acute myeloid leukemia: report of 82 patients enrolled in an Italian Compassionate Program.

  Cancer 20120215

• Genome-wide DNA methylation level analysis by micellar electrokinetic chromatography and laser-induced fluorescence detection after treatment of cell lines with azacytidine and antifolates.

  Analytical biochemistry 20120215

• Study on RIZ1 gene promoter methylation status in human esophageal squamous cell carcinoma.

  World journal of gastroenterology 20120214

• Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine.

  Blood 20120202

• ENDOGLIN/CD105 is expressed in KIT positive cells in the gut and in gastrointestinal stromal tumours.

  Journal of cellular and molecular medicine 20120201

• Inflammation-induced up-regulation of TLR2 expression in human endothelial cells is independent of differential methylation in the TLR2 promoter CpG island.

  Innate immunity 20120201

• CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors.

  Leukemia 20120201

• A phase I study of 5-azacytidine and erlotinib in advanced solid tumor malignancies.

  Cancer chemotherapy and pharmacology 20120201

• Histone H4 deacetylation down-regulates catalase gene expression in doxorubicin-resistant AML subline.

  Cell biology and toxicology 20120201

• Heparanase expression is associated with histone modifications in glioblastoma.

  International journal of oncology 20120201

• In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta.

  Environmental health perspectives 20120201

• In vitro study of the differentiation of bone marrow stromal cells into cardiomyocyte-like cells.

  Molecular and cellular biochemistry 20120201

• Effect of CpG island methylation on microRNA expression in the k-562 cell line.

  Biochemical genetics 20120201

• Modulation of volatile organic compound formation in the Mycodiesel-producing endophyte Hypoxylon sp. CI-4.

  Microbiology (Reading, England) 20120201

• Analysis of aberrant methylation in DNA repair genes during malignant transformation of human bronchial epithelial cells induced by cadmium.

  Toxicological sciences : an official journal of the Society of Toxicology 20120201

• Progression of prostate carcinogenesis and dietary methyl donors: temporal dependence.

  Cancer prevention research (Philadelphia, Pa.) 20120201

• CRABP-II methylation: a critical determinant of retinoic acid resistance of medulloblastoma cells.

  Molecular oncology 20120201

• Deletion or epigenetic silencing of AJAP1 on 1p36 in glioblastoma.

  Molecular cancer research : MCR 20120201

• Influence of epigenetic modifications of the interleukin-10 promoter on IL10 gene expression.

  European journal of oral sciences 20120201

• p53-Independent, normal stem cell sparing epigenetic differentiation therapy for myeloid and other malignancies.

  Seminars in oncology 20120201

• Epigenetic modulation to enable antigen-specific T-cell therapy of colorectal cancer.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20120201

• [Decitabine for treatment of myelodysplastic syndrome in an elderly patient and review of literature].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120201

• Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolytica.

  PLoS pathogens 20120201

• [Decitabine inhibits cell proliferation and induces apoptosis of all-trans retinoid acid-resistant acute promyelocytic leukemia NB4-R2 cell line].

  Zhongguo shi yan xue ye xue za zhi 20120201

• Rapid turnover of DNA methylation in human cells.

  Epigenetics 20120201

• A long road for stem cells to cure sick hearts: update on recent clinical trials.

  Korean circulation journal 20120201

• [Cell fusion as a key mechanism for cell-based therapy towards Duchenne muscular dystrophy].

  Seikagaku. The Journal of Japanese Biochemical Society 20120201

• [The comparison of short-term efficacies between decitabine and HA regimen for MDS/AML patients].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120201

• DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines.

  International journal of cancer 20120115

• Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases.

  The Journal of biological chemistry 20120113

• DNA methylation of the 5'-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells.

  Biochemical and biophysical research communications 20120106

• Satellite 2 demethylation induced by 5-azacytidine is associated with missegregation of chromosomes 1 and 16 in human somatic cells.

  Mutation research 20120103

• 5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinase.

  Stem cells and development 20120101

• 5-Azacytidine makes human preadipocytes able to differentiate into mesoderm-derived cell lineages.

  Stem cells and development 20120101

• Phase II study of the histone deacetylase inhibitor belinostat (PXD101) for the treatment of myelodysplastic syndrome (MDS).

  Annals of hematology 20120101

• Azacitidine in patients with acute myeloid leukemia medically unfit for or resistant to chemotherapy: a multicenter phase I/II study.

  Leukemia & lymphoma 20120101

• Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

  Advances in hematology 20120101

• Azacitidine in a patient with myelodysplastic syndrome: Impact of switching from a 5-day to the approved 7-day dosing schedule.

  Leukemia research 20120101

• HSPB8 is methylated in hematopoietic malignancies and overexpression of HSPB8 exhibits antileukemia effect.

  Experimental hematology 20120101

• The combination of angiotensin II and 5-azacytidine promotes cardiomyocyte differentiation of rat bone marrow mesenchymal stem cells.

  Molecular and cellular biochemistry 20120101

• Trichostatin a promotes cardiomyocyte differentiation of rat mesenchymal stem cells after 5-azacytidine induction or during coculture with neonatal cardiomyocytes via a mechanism independent of histone deacetylase inhibition.

  Cell transplantation 20120101

• Epigenetic drug discovery: targeting DNA methyltransferases.

  Journal of biomolecular screening 20120101

• Differentiation potential of human mesenchymal stem cells derived from adipose tissue and bone marrow to sinus node-like cells.

  Molecular medicine reports 20120101

• A cost-effectiveness analysis of using azacitidine vs. decitabine in treating patients with myelodysplastic syndromes.

  Journal of medical economics 20120101

• 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101

• Effect of 5-Aza-2'-deoxycytidine on SLC22A18 in glioma U251 cells.

  Molecular medicine reports 20120101

• Interstitial pneumonitis--An important differential diagnosis for pulmonary sepsis in haematology patients.

  Leukemia research 20120101

• Oxidative Stress Induced by MnSOD-p53 Interaction: Pro- or Anti-Tumorigenic?

  Journal of signal transduction 20120101

• Neurospora crassa Light Signal Transduction Is Affected by ROS.

  Journal of signal transduction 20120101

• CRABP-II- and FABP5-independent all-trans retinoic acid resistance in COLO 16 human cutaneous squamous cancer cells.

  Experimental dermatology 20120101

• Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout life.

  Endocrinology 20120101

• Signature of VDR miRNAs and epigenetic modulation of vitamin D signaling in melanoma cell lines.

  Anticancer research 20120101

• Antiretroviral activity of 5-azacytidine during treatment of a HTLV-1 positive myelodysplastic syndrome with autoimmune manifestations.

  Virology journal 20120101

• Combination strategies in myelodysplastic syndromes.

  International journal of hematology 20120101

• 5-Azacytidine is insufficient for cardiogenesis in human adipose-derived stem cells.

  Journal of negative results in biomedicine 20120101

• Emerging therapies in hematopoietic stem cell transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120101

• Monitoring and prevention of relapse after allogeneic hematopoietic cell transplantation for myeloid malignancies.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120101

• Engineered myocardial tissues constructed in vivo using cardiomyocyte-like cells derived from bone marrow mesenchymal stem cells in rats.

  Journal of biomedical science 20120101

• HIV infection and HERV expression: a review.

  Retrovirology 20120101

• Monitoring of methylation changes in 9p21 region in patients with myelodysplastic syndromes and acute myeloid leukemia.

  Neoplasma 20120101

• Defining the sister rat mammary tumor cell lines HH-16 cl.2/1 and HH-16.cl.4 as an in vitro cell model for Erbb2.

  PloS one 20120101

• Effects of a novel DNA methyltransferase inhibitor Zebularine on human lens epithelial cells.

  Molecular vision 20120101

• Regulation of opioid and cannabinoid receptor genes in human neuroblastoma and T cells by the epigenetic modifiers trichostatin A and 5-aza-2'-deoxycytidine.

  Neuroimmunomodulation 20120101

• Sca-1+ cardiosphere-derived cells are enriched for Isl1-expressing cardiac precursors and improve cardiac function after myocardial injury.

  PloS one 20120101

• Bisulfite sequencing reveals that Aspergillus flavus holds a hollow in DNA methylation.

  PloS one 20120101

• [Demethylating medication in myelodysplastic syndrome].

  Nederlands tijdschrift voor geneeskunde 20120101

• Oncolytic virotherapy for hematological malignancies.

  Advances in virology 20120101

• Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type.

  Journal of Cancer 20120101

• TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.

  PloS one 20120101

• The co-presence of deletion 7q, 20q and inversion 16 in therapy-related acute myeloid leukemia developed secondary to treatment of breast cancer with cyclophosphamide, doxorubicin, and radiotherapy: a case report.

  Journal of medical case reports 20120101

• DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.

  Chemotherapy 20120101

• Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway.

  Scientific reports 20120101

• Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.

  Nucleosides, nucleotides & nucleic acids 20120101

• Induction of sodium/iodide symporter (NIS) expression and radioiodine uptake in non-thyroid cancer cells.

  PloS one 20120101

• Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma.

  PloS one 20120101

• A novel classification of lung cancer into molecular subtypes.

  PloS one 20120101

• Instability of (CTG)n•(CAG)n trinucleotide repeats and DNA synthesis.

  Cell & bioscience 20120101

• Decreased expression of retinoblastoma protein-interacting zinc-finger gene 1 in human esophageal squamous cell cancer by DNA methylation.

  Clinical laboratory 20120101

• [MDS].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20120101

• Different involvement of DNA methylation and histone deacetylation in the expression of solute-carrier transporters in 4 colon cancer cell lines.

  Biological & pharmaceutical bulletin 20120101

• NYESO-1/LAGE-1s and PRAME are targets for antigen specific T cells in chondrosarcoma following treatment with 5-Aza-2-deoxycitabine.

  PloS one 20120101

• Cytogenetic and molecular predictors of response in patients with myeloid malignancies without del[5q] treated with lenalidomide.

  Journal of hematology & oncology 20120101

• Screening for epigenetically masked genes in colorectal cancer Using 5-Aza-2'-deoxycytidine, microarray and gene expression profile.

  Cancer genomics & proteomics 20120101

• Methylation of Wnt7a is modulated by DNMT1 and cigarette smoke condensate in non-small cell lung cancer.

  PloS one 20120101

• Epigenetic disregulation in oral cancer.

  International journal of molecular sciences 20120101

• The endogenous retrovirus ENS-1 provides active binding sites for transcription factors in embryonic stem cells that specify extra embryonic tissue.

  Retrovirology 20120101

• In planta assays involving epigenetically silenced genes reveal inhibition of cytosine methylation by genistein.

  Plant methods 20120101

• DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells.

  PloS one 20120101

• RNA-binding protein Musashi1 modulates glioma cell growth through the post-transcriptional regulation of Notch and PI3 kinase/Akt signaling pathways.

  PloS one 20120101

• DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity.

  Radiation oncology (London, England) 20120101

• Targeted drug regulation on methylation of p53-BAX mitochondrial apoptosis pathway affects the growth of cholangiocarcinoma cells.

  The Journal of international medical research 20120101

• Epigenetic modification of TLRs in leukocytes is associated with increased susceptibility to Salmonella enteritidis in chickens.

  PloS one 20120101

• IL-35 is a novel responsive anti-inflammatory cytokine--a new system of categorizing anti-inflammatory cytokines.

  PloS one 20120101

• Hiwi mediated tumorigenesis is associated with DNA hypermethylation.

  PloS one 20120101

• Rapidly growing ulcer in a patient with neurofibromatosis type I.

  Actas dermo-sifiliograficas 20120101

• Reversin increase the plasticity of bone marrow-derived mesenchymal stem cell for generation of cardiomyocyte in vitro.

  Acta medica Indonesiana 20120101

• Management of cutaneous T cell lymphoma: new and emerging targets and treatment options.

  Cancer management and research 20120101

• Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins.

  BMC cancer 20120101

• [5-aza-2'-deoxycytidine-induced inhibition of CDH13 expression and its inhibitory effect on methylation status in human colon cancer cells in vitro and on growth of xenograft in nude mice].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20120101

• Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers.

  PloS one 20120101

• Effect of cyclic strain on cardiomyogenic differentiation of rat bone marrow derived mesenchymal stem cells.

  PloS one 20120101

• Advances in Virus-Directed Therapeutics against Epstein-Barr Virus-Associated Malignancies.

  Advances in virology 20120101

• A novel intracellular isoform of matrix metalloproteinase-2 induced by oxidative stress activates innate immunity.

  PloS one 20120101

• Plant 45S rDNA clusters are fragile sites and their instability is associated with epigenetic alterations.

  PloS one 20120101

• Symbiodinium transcriptomes: genome insights into the dinoflagellate symbionts of reef-building corals.

  PloS one 20120101

• Epigenetics and autoimmune diseases.

  Autoimmune diseases 20120101

• Sodium iodide symporter for nuclear molecular imaging and gene therapy: from bedside to bench and back.

  Theranostics 20120101

• Azacytidine inhibits the proliferation of human promyelocytic leukemia cells (HL60) by demethylation of MGMT, DAPK and p16 genes.

  Hematology (Amsterdam, Netherlands) 20120101

• Long-term cultured human term placenta-derived mesenchymal stem cells of maternal origin displays plasticity.

  Stem cells international 20120101

• Histone deacetylase inhibitors in cell pluripotency, differentiation, and reprogramming.

  Stem cells international 20120101

• Analysis of embryoid bodies derived from human induced pluripotent stem cells as a means to assess pluripotency.

  Stem cells international 20120101

• A Case of Atypical Delayed and Prolonged Hematologic Toxicity With Azacitidine in Chronic Myelomonocytic Leukemia (CMML) and Review of Literature.

  Mediterranean journal of hematology and infectious diseases 20120101

• Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer.

  PloS one 20120101

• Antiproliferative effects of DNA methyltransferase 3B depletion are not associated with DNA demethylation.

  PloS one 20120101

• Daphnia as an emerging epigenetic model organism.

  Genetics research international 20120101

• Utility of DNA methyltransferase inhibitors for the treatment of myelodysplastic syndromes.

  Current pharmaceutical design 20120101

• Approach to new therapeutics: investigation by the use of MDS-derived cell lines.

  Current pharmaceutical design 20120101

• Influence of nanomaterials on stem cell differentiation: designing an appropriate nanobiointerface.

  International journal of nanomedicine 20120101

• TCUP: A Novel hAT Transposon Active in Maize Tissue Culture.

  Frontiers in plant science 20120101

• Epigenetics modifications and therapeutic prospects in human thyroid cancer.

  Frontiers in endocrinology 20120101

• Acute myeloid leukemia: focus on novel therapeutic strategies.

  Clinical Medicine Insights. Oncology 20120101

• FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.

  Anemia 20120101

• Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

  PloS one 20120101

• Demethylation of the coding region triggers the activation of the human testis-specific PDHA2 gene in somatic tissues.

  PloS one 20120101

• The two-component sensor kinase TcsC and its role in stress resistance of the human-pathogenic mold Aspergillus fumigatus.

  PloS one 20120101

• 5-Methylcytosine and 5-hydroxymethylcytosine spatiotemporal profiles in the mouse zygote.

  PloS one 20120101

• Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming.

  Stem cells international 20120101

• Cancer-type regulation of MIG-6 expression by inhibitors of methylation and histone deacetylation.

  PloS one 20120101

• Molecular mechanisms of induced pluripotency.

  Acta naturae 20120101

• Diagnosis and therapy of myelodysplastic syndromes in Germany: a retrospective multicenter analysis.

  Onkologie 20120101

• Effect of phenylhexyl isothiocyanate on aberrant histone H3 methylation in primary human acute leukemia.

  Journal of hematology & oncology 20120101

• Safety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndrome.

  Clinical interventions in aging 20120101

• The effects of promoter methylation on downregulation of DAZAP2 in multiple myeloma cell lines.

  PloS one 20120101

• Tamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancer.

  PloS one 20120101

• Outcome of therapy-related myeloid neoplasms treated with azacitidine.

  Journal of hematology & oncology 20120101

• Identification of CBX3 and ABCA5 as putative biomarkers for tumor stem cells in osteosarcoma.

  PloS one 20120101

• Aberrant promoter methylation and expression of UTF1 during cervical carcinogenesis.

  PloS one 20120101

• ING1 and 5-azacytidine act synergistically to block breast cancer cell growth.

  PloS one 20120101

• Murine models of lupus induced by hypomethylated T cells (DNA hypomethylation and lupus…).

  Methods in molecular biology (Clifton, N.J.) 20120101

• Treatment of chronic myelomonocytic leukemia with 5-azacytidine: case reports.

  Case reports in hematology 20120101

• Gene expression profiling of the synergy of 5-aza-2'-deoxycytidine and paclitaxel against renal cell carcinoma.

  World journal of surgical oncology 20120101

• Transcriptional regulation of hTREX84 in human cancer cells.

  PloS one 20120101

• Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines.

  PloS one 20120101

• Effect of 5-azacytidine on in vitro biofilm formation of Streptococcus pneumoniae.

  Microbial pathogenesis 20120101

• Azacitidine-induced pneumonitis in a patient with myelodysplastic syndrome: first case report in Japan.

  Internal medicine (Tokyo, Japan) 20120101

• Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine.

  PloS one 20120101

• Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis.

  PloS one 20120101

• 5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes.

  PloS one 20120101

• Alterations of the WNT7A gene in clear cell renal cell carcinomas.

  PloS one 20120101

• Silencing of glutathione peroxidase 3 through DNA hypermethylation is associated with lymph node metastasis in gastric carcinomas.

  PloS one 20120101

• Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation.

  PloS one 20120101

• MeCP2 controls the expression of RASAL1 in the hepatic fibrosis in rats.

  Toxicology 20111218

• S-Adenosylhomocysteine enhances DNA damage through increased β-amyloid formation and inhibition of the DNA-repair enzyme OGG1b in microglial BV-2 cells.

  Toxicology 20111218

• C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells.

  European journal of pharmacology 20111215

• The secret lives of stem cells: unraveling the molecular basis of stem cell aging.

  Cell cycle (Georgetown, Tex.) 20111215

• 5-aza-2'-deoxycytidine enhances susceptibility of renal cell carcinoma to paclitaxel by decreasing LEF1/phospho-β-catenin expression.

  Cancer letters 20111208

• Primary CNS lymphoma other than DLBCL: a descriptive analysis of clinical features and treatment outcomes.

  Annals of hematology 20111201

• Effects of epigenetic-based anti-cancer drugs in leukaemia and multiple myeloma cells.

  Cell biology international 20111201

• DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts.

  Genes and immunity 20111201

• Role of BCL2L10 methylation and TET2 mutations in higher risk myelodysplastic syndromes treated with 5-azacytidine.

  Leukemia 20111201

• The association between non-Hodgkin lymphoma and methylation of p73.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111201

• Survival benefits from reduced-intensity conditioning in allogeneic stem cell transplantation for young lower-risk MDS patients without significant comorbidities.

  European journal of haematology 20111201

• Modulation of protein expression levels and DNA methylation status of breast cancer metastasis genes by anthracycline-based chemotherapy and the demethylating agent decitabine.

  Cell biochemistry and function 20111201

• Reversal of epigenetic silencing of AP-2alpha results in increased zinc uptake in DU-145 and LNCaP prostate cancer cells.

  Carcinogenesis 20111201

• Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer.

  International journal of cancer 20111201

• Platelet doubling after the first azacitidine cycle is a promising predictor for response in myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML) patients in the Dutch azacitidine compassionate named patient programme.

  British journal of haematology 20111201

• The seminoma cell line TCam-2 is sensitive to HDAC inhibitor depsipeptide but tolerates various other chemotherapeutic drugs and loss of NANOG expression.

  Genes, chromosomes & cancer 20111201

• Epigenetic regulation of glucose transporter 4 by estrogen receptor β.

  Molecular endocrinology (Baltimore, Md.) 20111201

• DNA methylation and soy phytoestrogens: quantitative study in DU-145 and PC-3 human prostate cancer cell lines.

  Epigenomics 20111201

• What is the optimal induction strategy for older patients?

  Best practice & research. Clinical haematology 20111201

• Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines.

  Epigenetics 20111201

• [Poliovirus receptor on surface of acute B lymphoid leukemia cells modulated by epigenetic mechanism].

  Zhongguo shi yan xue ye xue za zhi 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• [Effect of methylation inhibitor on demethylation pattern of the PD-1 gene in promoter region and PD-1 expression in human T lymphocyte cell line].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20111201

• Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer.

  Oncotarget 20111201

• Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer.

  Cancer discovery 20111201

• Epigenetic inactivation of the MIR34B/C in multiple myeloma.

  Blood 20111124

• HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL.

  Blood 20111117

• Chromatin-modifying drugs induce miRNA-153 expression to suppress Irs-2 in glioblastoma cell lines.

  International journal of cancer 20111115

• CpG methylation at the USF-binding site mediates cell-specific transcription of human ascorbate transporter SVCT2 exon 1a.

  The Biochemical journal 20111115

• Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20111115

• MAGE: the spell is broken.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20111115

• Immunotherapy augments the effect of 5-azacytidine on HPV16-associated tumours with different MHC class I-expression status.

  British journal of cancer 20111108

• Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter.

  FEBS letters 20111104

• Amyloid protein-mediated differential DNA methylation status regulates gene expression in Alzheimer's disease model cell line.

  Biochemical and biophysical research communications 20111104

• Expression of tyrosine hydroxylase is epigenetically regulated in neural stem cells.

  Biochemical and biophysical research communications 20111104

• Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells.

  Breast cancer research and treatment 20111101

• 5-Aza-2'-deoxycytidine and interleukin-1 cooperate to regulate matrix metalloproteinase-3 gene expression.

  International journal of cancer 20111101

• Histonedeacetylase inhibitor Oxamflatin increase HIV-1 transcription by inducing histone modification in latently infected cells.

  Molecular biology reports 20111101

• Reactivation of transgene expression by alleviating CpG methylation of the Rous sarcoma virus promoter in transgenic quail cells.

  Molecular biotechnology 20111101

• A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma.

  The European respiratory journal 20111101

• Epigenetic inactivation of the SFRP1 gene in esophageal squamous cell carcinoma.

  Digestive diseases and sciences 20111101

• Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors.

  British journal of pharmacology 20111101

• p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia.

  Leukemia 20111101

• Acute myeloid leukemia with mutated nucleophosmin (NPM1): any hope for a targeted therapy?

  Blood reviews 20111101

• Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer.

  Breast cancer research and treatment 20111101

• Azacitidine induces demethylation of p16INK4a and inhibits growth in adult T-cell leukemia/lymphoma.

  International journal of molecular medicine 20111101

• Epigenetics: DNA demethylation promotes skeletal myotube maturation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111101

• γ-radiation induces cellular sensitivity and aberrant methylation in human tumor cell lines.

  International journal of radiation biology 20111101

• Acquired alpha thalassemia myelodyslastic/myeloproliferative syndrome (ATMDS): evolution on hypomethylating agent therapy.

  Leukemia research 20111101

• Impact of the hypomethylating agent 5-azacytidine on dendritic cells function.

  Experimental hematology 20111101

• Histone modifications and methyl-CpG-binding domain protein levels at the TNFSF7 (CD70) promoter in SLE CD4+ T cells.

  Lupus 20111101

• WIF1 is a frequent target for epigenetic silencing in squamous cell carcinoma of the cervix.

  Carcinogenesis 20111101

• The subpopulation of mesenchymal stem cells that differentiate toward cardiomyocytes is cardiac progenitor cells.

  Experimental cell research 20111101

• Expression and immunotherapeutic targeting of the SSX family of cancer-testis antigens in prostate cancer.

  Cancer research 20111101

• Cancer-testis antigen expression and its epigenetic modulation in acute myeloid leukemia.

  American journal of hematology 20111101

• Cytogenetic and molecular abnormalities in myelodysplastic syndrome.

  Current molecular medicine 20111101

• The regulation of MASPIN expression in epithelial ovarian cancer: association with p53 status, and MASPIN promoter methylation: a gynecologic oncology group study.

  Gynecologic oncology 20111101

• Hypomethylation of proximal CpG motif of interleukin-10 promoter regulates its expression in human rheumatoid arthritis.

  Acta pharmacologica Sinica 20111101

• Decitabine, independent of apoptosis, exerts its cytotoxic effects on cell growth in melanoma cells.

  Environmental toxicology and pharmacology 20111101

• Rapid isolation of adipose tissue-derived stem cells by the storage of lipoaspirates.

  Yonsei medical journal 20111101

• Epigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytes.

  Nucleus (Austin, Tex.) 20111101

• DNA methylation patterns of Brachypodium distachyon chromosomes and their alteration by 5-azacytidine treatment.

  Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20111101

• 5-AZA-2'-deoxycytidine induced demethylation influences N-glycosylation of secreted glycoproteins in ovarian cancer.

  Epigenetics 20111101

• The effect of epigenetic factors on differentiation of pancreatic progenitor cells into insulin-producing cells.

  Transplantation proceedings 20111101

• 5-azacytidine reverses drug resistance in bladder cancer cells.

  Anticancer research 20111101

• [Effect of methylation modification on the expression of Cosmc gene in peripheral B lymphocyte of IgA nephropathy patients].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20111101

• [The clinical research of treatment by decitabine moderate or high-risk myelodysplastic syndrome patients].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20111101

• 5-aza-2'-deoxycytidine activates iron uptake and heme biosynthesis by increasing c-Myc nuclear localization and binding to the E-boxes of transferrin receptor 1 (TfR1) and ferrochelatase (Fech) genes.

  The Journal of biological chemistry 20111028

• Therapy related acute myeloid leukemia with t(10:16): a rare entity.

  Hematology reports 20111019

• Intrathecal 5-azacytidine inhibits global DNA methylation and methyl- CpG-binding protein 2 expression and alleviates neuropathic pain in rats following chronic constriction injury.

  Brain research 20111018

• Analysis of expression and structure of the rat GH-secretagogue/ghrelin receptor (Ghsr) gene: roles of epigenetic modifications in transcriptional regulation.

  Molecular and cellular endocrinology 20111015

• FMR1 CGG repeat lengths mediate different regulation of reporter gene expression in comparative transient and locus specific integration assays.

  Gene 20111015

• [Aberrant methylation of T-cadherin gene in human esophageal carcinoma cells].

  Zhonghua yi xue za zhi 20111011

• Aberrant methylation of the 3q25 tumor suppressor gene PTX3 in human esophageal squamous cell carcinoma.

  World journal of gastroenterology 20111007

• Molecular predictors of response to decitabine in advanced chronic myelomonocytic leukemia: a phase 2 trial.

  Blood 20111006

• In vitro investigation and biomechanical modeling of the effects of PLF-68 on osteoarthritis in a three-dimensional model.

  Biomechanics and modeling in mechanobiology 20111001

• Aberrant CpG island hypermethylation and down-regulation of Oct-6 mRNA expression in human hepatocellular carcinoma.

  Digestive diseases and sciences 20111001

• Decitabine and suberoylanilide hydroxamic acid (SAHA) inhibit growth of ovarian cancer cell lines and xenografts while inducing expression of imprinted tumor suppressor genes, apoptosis, G2/M arrest, and autophagy.

  Cancer 20111001

• A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome.

  Haematologica 20111001

• 5'-Azacitidine for therapy-related myelodysplastic syndromes after non-Hodgkin lymphoma treatment.

  Leukemia research 20111001

• Epigenetic regulation of alkaline phosphatase in human cells of the osteoblastic lineage.

  Bone 20111001

• Minimal residual disease-directed preemptive treatment with azacitidine in patients with NPM1-mutant acute myeloid leukemia and molecular relapse.

  Haematologica 20111001

• Cautions regarding the fitting and interpretation of survival curves: examples from NICE single technology appraisals of drugs for cancer.

  PharmacoEconomics 20111001

• Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.

  Carcinogenesis 20111001

• Targeting HSP 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma.

  Molecular cancer therapeutics 20111001

• Neuronal activity modifies the DNA methylation landscape in the adult brain.

  Nature neuroscience 20111001

• Hematopoietic growth factors in myelodysplastic syndromes.

  Seminars in oncology 20111001

• Treatment of higher-risk myelodysplastic syndrome.

  Seminars in oncology 20111001

• Failure of hypomethylating agent-based therapy in myelodysplastic syndromes.

  Seminars in oncology 20111001

• Epigenetic modifiers exert renal toxicity through induction of p66shc.

  Anticancer research 20111001

• [Novel therapeutics for myelodysplastic syndromes].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20111001

• Direct lineage conversions: unnatural but useful?

  Nature biotechnology 20111001

• [Silence mechanism of WT1 gene in leukemic cell line U937].

  Zhongguo shi yan xue ye xue za zhi 20111001

• RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus.

  PLoS pathogens 20111001

• The molecular biology of frog virus 3 and other iridoviruses infecting cold-blooded vertebrates.

  Viruses 20111001

• Epigenomics in hematopoietic transplantation: novel treatment strategies.

  Epigenomics 20111001

• Successful allogeneic stem-cell transplantation in a patient with myelodysplastic syndrome with hemodialysis-dependent end-stage renal disease.

  Transplantation 20110927

• Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate.

  Oncogene 20110922

• Inhibition of p53 represses E-cadherin expression by increasing DNA methyltransferase-1 and promoter methylation in serous borderline ovarian tumor cells.

  Oncogene 20110915

• Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor.

  Analytical chemistry 20110915

• News on hypomethylating agents: chasing the FOX.

  Cell cycle (Georgetown, Tex.) 20110915

• A pilot study of subcutaneous decitabine in β-thalassemia intermedia.

  Blood 20110908

• Lycopene and apo-10'-lycopenal do not alter DNA methylation of GSTP1 in LNCaP cells.

  Biochemical and biophysical research communications 20110902

• Epigenetic regulation of DNA methyltransferases: DNMT1 and DNMT3B in gliomas.

  Journal of neuro-oncology 20110901

• Hypomethylating agents for the treatment of acute myeloid leukemia in the elderly: for all, none, or which patients?

  Cancer 20110901

• Laser-captured microdissection-microarray analysis of the genes involved in endometrial carcinogenesis: stepwise up-regulation of lipocalin2 expression in normal and neoplastic endometria and its functional relevance.

  Human pathology 20110901

• Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine.

  Leukemia research 20110901

• A sex-chromosome mutation in Silene latifolia.

  Sexual plant reproduction 20110901

• Effect of trichostatin A and 5-Aza-2'-deoxycytidine on transgene reactivation and epigenetic modification in transgenic pig fibroblast cells.

  Molecular and cellular biochemistry 20110901

• Increased PRAME antigen-specific killing of malignant cell lines by low avidity CTL clones, following treatment with 5-Aza-2'-Deoxycytidine.

  Cancer immunology, immunotherapy : CII 20110901

• Phase I and II study of azacitidine in Japanese patients with myelodysplastic syndromes.

  Cancer science 20110901

• MAGE-A1, MAGE-A3, and NY-ESO-1 can be upregulated on neuroblastoma cells to facilitate cytotoxic T lymphocyte-mediated tumor cell killing.

  Cancer immunology, immunotherapy : CII 20110901

• Decreased expression of protease-activated receptor 4 in human gastric cancer.

  The international journal of biochemistry & cell biology 20110901

• The DNA methylome of benign and malignant parathyroid tumors.

  Genes, chromosomes & cancer 20110901

• Transformation-dependent silencing of tumor-selective apoptosis-inducing TRAIL by DNA hypermethylation is antagonized by decitabine.

  Molecular cancer therapeutics 20110901

• Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3B1, a novel epithelial-mesenchymal transition inducer in pancreatic cancer.

  Cancer biology & therapy 20110901

• Definition of the landscape of promoter DNA hypomethylation in liver cancer.

  Cancer research 20110901

• Identification of mutations conferring 5-azacytidine resistance in bacteriophage Qβ.

  Virology 20110901

• Hypomethylating agents in the treatment of myelodysplastic syndromes and myeloid leukemia.

  Current cancer drug targets 20110901

• Exon 11 skipping of E-cadherin RNA downregulates its expression in head and neck cancer cells.

  Molecular cancer therapeutics 20110901

• Transplantation of induced bone marrow mesenchymal stem cells improves the cardiac function of rabbits with dilated cardiomyopathy via upregulation of vascular endothelial growth factor and its receptors.

  Experimental biology and medicine (Maywood, N.J.) 20110901

• NOR1 is an HSF1- and NRF1-regulated putative tumor suppressor inactivated by promoter hypermethylation in nasopharyngeal carcinoma.

  Carcinogenesis 20110901

• Combination decitabine, arsenic trioxide, and ascorbic acid for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a phase I study.

  American journal of hematology 20110901

• TCF21 and PCDH17 methylation: An innovative panel of biomarkers for a simultaneous detection of urological cancers.

  Epigenetics 20110901

• Dynamics of bivalent chromatin domains upon drug induced reactivation and resilencing in cancer cells.

  Epigenetics 20110901

• Coordinated epigenetic regulation of autophagy and apoptosis.

  Cell cycle (Georgetown, Tex.) 20110901

• Murine gamma-herpesvirus immortalization of fetal liver-derived B cells requires both the viral cyclin D homolog and latency-associated nuclear antigen.

  PLoS pathogens 20110901

• Hypomethylation of the hsa-miR-191 locus causes high expression of hsa-mir-191 and promotes the epithelial-to-mesenchymal transition in hepatocellular carcinoma.

  Neoplasia (New York, N.Y.) 20110901

• Retrotransposon-induced heterochromatin spreading in the mouse revealed by insertional polymorphisms.

  PLoS genetics 20110901

• Complete remission of Waldenström macroglobulinemia with azacitidine and rituximab.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820

• Outcome of high-risk myelodysplastic syndrome after azacitidine treatment failure.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820

• Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.

  Blood 20110811

• Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni.

  Nature communications 20110809

• Identification of methylation profile of HOX genes in extrahepatic cholangiocarcinoma.

  World journal of gastroenterology 20110807

• MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia.

  Oncogene 20110804

• Human BM stem cells initiate angiogenesis in human islets in vitro.

  Bone marrow transplantation 20110801

• Promoter hypermethylation of cyclooxygenase-2 gene in esophageal squamous cell carcinoma.

  Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110801

• Interferon-alpha induces reversible DNA demethylation of the interferon-induced transmembrane protein-3 core promoter in human melanoma cells.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20110801

• Thrice weekly azacitidine does not improve hematological responses in lower-risk myelodysplastic syndromes: a study of the Hoosier Oncology Group.

  Leukemia research 20110801

• DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.

  European journal of cancer (Oxford, England : 1990) 20110801

• Inhibition of p53-p21 pathway promotes the differentiation of rat bone marrow mesenchymal stem cells into cardiomyocytes.

  Molecular and cellular biochemistry 20110801

• The effects of 5-aza-2'- deoxycytidine and trichostatin A on gene expression and DNA methylation status in cloned bovine blastocysts.

  Cellular reprogramming 20110801

• Delineation of the molecular mechanisms of nucleoside recognition by cytidine deaminase through virtual screening.

  ChemMedChem 20110801

• Use of integrative epigenetic and cytogenetic analyses to identify novel tumor-suppressor genes in malignant melanoma.

  Melanoma research 20110801

• Cytogenetic response is not a prerequisite for clinical response in patients with myelodysplastic syndromes treated with azacitidine.

  European journal of haematology 20110801

• Cellular DNA methylation program during neurulation and its alteration by alcohol exposure.

  Birth defects research. Part A, Clinical and molecular teratology 20110801

• MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer.

  Carcinogenesis 20110801

• The effect of decitabine on megakaryocyte maturation and platelet release.

  Thrombosis and haemostasis 20110801

• The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression.

  Epigenetics 20110801

• Proteasome inhibition in myelodysplastic syndromes and acute myelogenous leukemia cell lines.

  Cancer investigation 20110801

• Methylation of specific CpG sites in the P2 promoter of parathyroid hormone-related protein determines the invasive potential of breast cancer cell lines.

  Epigenetics 20110801

• The application of delivery systems for DNA methyltransferase inhibitors.

  BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110801

• Hematologic outcomes of myelodysplastic syndromes treatment with hypomethylating agents in community practice.

  Clinical lymphoma, myeloma & leukemia 20110801

• [Hypomethylating agents for the treatment of myelodysplastic syndromes].

  Bulletin du cancer 20110801

• [Effects of decitabine on biological behavior of U266 cells].

  Zhongguo shi yan xue ye xue za zhi 20110801

• Downregulation of ARFGEF1 and CAMK2B by promoter hypermethylation in breast cancer cells.

  BMB reports 20110801

• Methylation-associated dysregulation of the suppressor of cytokine signaling-3 gene in multiple myeloma.

  Epigenetics 20110801

• [The effects of pulsed electromagnetic fields on the induction of rat bone marrow mesenchymal stem cells to differentiate into cardiomyocytes-like cells in vitro].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20110801

• Expression profiling of non-aflatoxigenic Aspergillus parasiticus mutants obtained by 5-azacytosine treatment or serial mycelial transfer.

  Toxins 20110801

• [Differentiation of porcine amniotic fluid stem cells into the beating cardiomyocytes].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20110801

• [Mechanism of loss of human esophageal cancer-related gene 4 (ECRG4) gene expression in esophageal squamous cell carcinoma cell line EC9706].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110801

• Epigenetic regulation of prostate cancer.

  Clinical epigenetics 20110801

• The biological basis and clinical significance of hormonal imprinting, an epigenetic process.

  Clinical epigenetics 20110801

• Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies.

  Clinical epigenetics 20110801

• Epigenetic management of major psychosis.

  Clinical epigenetics 20110801

• Long interspersed nuclear element-1 hypomethylation in cancer: biology and clinical applications.

  Clinical epigenetics 20110801

• Treatment of poor-risk myelodysplastic syndromes and acute myeloid leukemia with a combination of 5-azacytidine and valproic acid.

  Clinical epigenetics 20110801

• Epigenetic approaches in stem cell transplantation.

  Clinical epigenetics 20110801

• Aberrant DNA hypermethylation of the ITIH5 tumor suppressor gene in acute myeloid leukemia.

  Clinical epigenetics 20110801

• Evolutional and clinical implications of the epigenetic regulation of protein glycosylation.

  Clinical epigenetics 20110801

• The role of promoter methylation in Epstein-Barr virus (EBV) microRNA expression in EBV-infected B cell lines.

  Experimental & molecular medicine 20110731

• Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells.

  Toxicology 20110729

• Nongenetic reprogramming of a fungal highly reducing polyketide synthase.

  Journal of the American Chemical Society 20110720

• Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells.

  Nature neuroscience 20110717

• Epigenetic mechanisms for silencing glutathione S-transferase m2 expression by hypermethylated specificity protein 1 binding in lung cancer.

  Cancer 20110715

• MicroRNA-146a downregulates NFκB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110715

• Azacitidine-resistant SKM1 myeloid cells are defective for AZA-induced mitochondrial apoptosis and autophagy.

  Cell cycle (Georgetown, Tex.) 20110715

• Hypomethylating agents reactivate FOXO3A in acute myeloid leukemia.

  Cell cycle (Georgetown, Tex.) 20110715

• Effect of 5-azacytidine: evidence for alteration of the multipotent ability of mesenchymal stem cells.

  Stem cells and development 20110701

• Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes.

  Leukemia research 20110701

• Response to 5-azacytidine in a patient with relapsed Hodgkin Lymphoma and a therapy-related myelodysplastic syndrome.

  British journal of haematology 20110701

• A novel, efficient method to derive bovine and mouse embryonic stem cells with in vivo differentiation potential by treatment with 5-azacytidine.

  Theriogenology 20110701

• Recurrent DNMT3A mutations in patients with myelodysplastic syndromes.

  Leukemia 20110701

• Changes in the levels of DNA methylation in testis and liver of SD rats neonatally exposed to 5-aza-2'-deoxycytidine and cadmium.

  Journal of applied toxicology : JAT 20110701

• The in vivo induction of sister chromatid exchange by the demethylating agent 5-aza-2'-deoxycytidine.

  Mutagenesis 20110701

• Prognostic significance of monosomal karyotype in higher risk myelodysplastic syndrome treated with azacitidine.

  Leukemia 20110701

• DNMT3B gene amplification predicts resistance to DNA demethylating drugs.

  Genes, chromosomes & cancer 20110701

• Methylation silencing of angiopoietin-like 4 in rat and human mammary carcinomas.

  Cancer science 20110701

• Impact of TET2 mutations on response rate to azacitidine in myelodysplastic syndromes and low blast count acute myeloid leukemias.

  Leukemia 20110701

• Mitochondria determine the differentiation potential of cardiac mesoangioblasts.

  Stem cells (Dayton, Ohio) 20110701

• Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.

  Leukemia research 20110701

• Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110701

• EFEMP1 as a novel DNA methylation marker for prostate cancer: array-based DNA methylation and expression profiling.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110701

• Loss of special AT-rich binding protein 1 expression is a marker of poor survival in lung cancer.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110701

• The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy.

  Cancer investigation 20110701

• [High glucose induce the demethylation of CTGF promoter and gene expression].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701

• Antiproliferation and redifferentiation in thyroid cancer cell lines by polyphenol phytochemicals.

  Journal of Korean medical science 20110701

• [Epigenetic therapy in myelodysplastic syndromes].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20110701

• Mesoangioblasts of inclusion-body myositis: a twofold tool to study pathogenic mechanisms and enhance defective muscle regeneration.

  Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20110701

• [Treatment of two chronic myelomonocytic leukemia patients with Decitabine].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110701

• Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway.

  Molecules and cells 20110630

• Protection of bone marrow-derived CD45+/CD34-/lin- stromal cells with immunosuppressant activity against ischemia/reperfusion injury in rats.

  The Chinese journal of physiology 20110630

• Phase I study of oral azacitidine in myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110620

• Azacytidine impairs NK cell reactivity while decitabine augments NK cell responsiveness toward stimulation.

  International journal of cancer 20110615

• Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.

  Analytical chemistry 20110615

• Activity of azacitidine in chronic myelomonocytic leukemia.

  Cancer 20110615

• Continued azacitidine therapy beyond time of first response improves quality of response in patients with higher-risk myelodysplastic syndromes.

  Cancer 20110615

• Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism.

  The Journal of biological chemistry 20110603

• The autoimmune manifestations associated with myelodysplastic syndrome respond to 5-azacytidine: a report on three cases.

  British journal of haematology 20110601

• Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20110601

• Expression of the human cancer/testis antigen NY-SAR-35 is activated by CpG island hypomethylation.

  Biotechnology letters 20110601

• Histone deacetylase inhibitors upregulate Rap1GAP and inhibit Rap activity in thyroid tumor cells.

  Endocrine-related cancer 20110601

• Clinical significance of expression of Hint1 and potential epigenetic mechanism in gastric cancer.

  International journal of oncology 20110601

• A demethylating agent enhances chemosensitivity to vinblastine in a xenograft model of renal cell carcinoma.

  International journal of oncology 20110601

• Protein inhibitor of activated STAT3 expression in lung cancer.

  Molecular oncology 20110601

• Ultra-performance liquid chromatography/tandem mass spectrometry for accurate quantification of global DNA methylation in human sperms.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601

• Transcription intermediary factor 1γ is a tumor suppressor in mouse and human chronic myelomonocytic leukemia.

  The Journal of clinical investigation 20110601

• Use of hypomethylating agents and associated care in patients with myelodysplastic syndromes: a claims database study.

  Current medical research and opinion 20110601

• 2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential.

  Epigenetics 20110601

• Adverse effects of azacitidine: onset, duration, and treatment.

  Advances in therapy 20110601

• Azacitidine adverse effects in patients with myelodysplastic syndromes.

  Advances in therapy 20110601

• Epigenetically silenced miR-34b/c as a novel faecal-based screening marker for colorectal cancer.

  British journal of cancer 20110524

• Low-dose decitabine versus best supportive care in elderly patients with intermediate- or high-risk myelodysplastic syndrome (MDS) ineligible for intensive chemotherapy: final results of the randomized phase III study of the European Organisation for Research and Treatment of Cancer Leukemia Group and the German MDS Study Group.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520

• Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions.

  International journal of cancer 20110515

• Acute myocarditis induced by hypomethylating agents.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510

• 5-azacytidine as salvage treatment in relapsed myeloid tumors after allogeneic bone marrow transplantation.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501

• Epigenetic modulation of MAGE-A3 antigen expression in multiple myeloma following treatment with the demethylation agent 5-azacitidine and the histone deacetlyase inhibitor MGCD0103.

  Cytotherapy 20110501

• Treating myelodysplastic syndrome improves an accompanying autoimmune disease along with a reduction in regulatory T-cells.

  Leukemia research 20110501

• The anti-leukemic effect and molecular mechanisms of novel hydroxamate and benzamide histone deacetylase inhibitors with 5-aza-cytidine.

  International journal of oncology 20110501

• DNA methylation restricts spontaneous multi-lineage differentiation of mesenchymal progenitor cells, but is stable during growth factor-induced terminal differentiation.

  Biochimica et biophysica acta 20110501

• Epigenetic modulation enhances the therapeutic effect of anti-IL-13R(alpha)2 antibody in human mesothelioma xenografts.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110501

• Hypermethylation-modulated down-regulation of CDH1 expression contributes to the progression of esophageal cancer.

  International journal of molecular medicine 20110501

• Azacitidine combined with gemtuzumab ozogamicin in patients with relapsed/refractory acute myeloid leukemia.

  Leukemia & lymphoma 20110501

• Epigenetics and its implications for ecotoxicology.

  Ecotoxicology (London, England) 20110501

• Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.

  Thyroid : official journal of the American Thyroid Association 20110501

• In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.

  The European journal of neuroscience 20110501

• Azacitidine: a new medication associated with Sweet syndrome.

  Journal of the American Academy of Dermatology 20110501

• Modulation of the poliovirus receptor expression in malignant lymphocytes by epigenetic alterations.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20110501

• Multipotent mesenchymal stromal cells express FoxP3: a marker for the immunosuppressive capacity?

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20110501

• Pharmacokinetic evaluation of decitabine for the treatment of leukemia.

  Expert opinion on drug metabolism & toxicology 20110501

• Mouse models of graft-versus-host disease: advances and limitations.

  Disease models & mechanisms 20110501

• The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine.

  Cell death & disease 20110501

• [Promoter methylation status of hPer3 gene in AML patients and the in vitro effect of decitabine on the status].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110501

• [Reversal effect of 5-Aza-dc on cisplatin-resistance in human NSCLC cells in vitro].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20110501

• Effective myotube formation in human adipose tissue-derived stem cells expressing dystrophin and myosin heavy chain by cellular fusion with mouse C2C12 myoblasts.

  Biochemical and biophysical research communications 20110429

• Wnt antagonist DKK1 acts as a tumor suppressor gene that induces apoptosis and inhibits proliferation in human renal cell carcinoma.

  International journal of cancer 20110415

• Aberrant methylation of the X-linked ribosomal S6 kinase RPS6KA6 (RSK4) in endometrial cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110415

• Phase 1b-2a study to reverse platinum resistance through use of a hypomethylating agent, azacitidine, in patients with platinum-resistant or platinum-refractory epithelial ovarian cancer.

  Cancer 20110415

• Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas.

  Breast cancer research and treatment 20110401

• Histone methylation is a critical regulator of the abnormal expression of POU5F1 and RASSF1A in testis cancer cell lines.

  International journal of andrology 20110401

• 5-Azacytidine in myelodysplastic syndromes: a clinical practice guideline.

  Cancer treatment reviews 20110401

• Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome.

  Leukemia research 20110401

• Aberrant methylation of the RIZ1 gene in myelodysplastic syndrome and acute myeloid leukemia.

  Leukemia research 20110401

• Gene expression profiling of myelodysplastic CD34+ hematopoietic stem cells treated in vitro with decitabine.

  Leukemia research 20110401

• Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial.

  Annals of hematology 20110401

• Epigenetic modification involved in benzene-induced apoptosis through regulating apoptosis-related genes expression.

  Cell biology international 20110401

• Decitabine-induced apoptosis is derived by Puma and Noxa induction in chronic myeloid leukemia cell line as well as in PBL and is potentiated by SAHA.

  Molecular and cellular biochemistry 20110401

• 5-Aza-2'-deoxycytidine increases sialyl Lewis X on MUC1 by stimulating β-galactoside:α2,3-sialyltransferase 6 gene.

  The international journal of biochemistry & cell biology 20110401

• Reduction of Fas/CD95 promoter methylation, upregulation of Fas protein, and enhancement of sensitivity to apoptosis in cutaneous T-cell lymphoma.

  Archives of dermatology 20110401

• Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors.

  Surgery 20110401

• (-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells.

  Carcinogenesis 20110401

• Differentiation induction of cardiac c-kit positive cells from rat heart into sinus node-like cells by 5-azacytidine.

  Tissue & cell 20110401

• GPR54 is a target for suppression of metastasis in endometrial cancer.

  Molecular cancer therapeutics 20110401

• 5'-azacitidine in myelodysplastic syndromes with inversion of chromosome 3.

  Leukemia 20110401

• Epigenetic gene silencing is a novel mechanism involved in delayed manifestation of radiation-induced genomic instability in mammalian cells.

  Radiation research 20110401

• Quantitative assessment of AKAP12 promoter methylation in human prostate cancer using methylation-sensitive high-resolution melting: correlation with Gleason score.

  Urology 20110401

• Interleukin-6 expression was regulated by epigenetic mechanisms in response to influenza virus infection or dsRNA treatment.

  Molecular immunology 20110401

• Epigenetic regulation in myelodysplastic syndromes: implications for therapy.

  Expert opinion on investigational drugs 20110401

• Stability of azacitidine suspensions.

  The Annals of pharmacotherapy 20110401

• Abnormal methylation of histone deacetylase genes: implications on etiology and epigenetic therapy of astrocytomas.

  Anticancer research 20110401

• NICE guidance on azacitidine for the treatment of myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia.

  The Lancet. Oncology 20110401

• Down-regulation of NDRG2 gene expression in human colorectal cancer involves promoter methylation and microRNA-650.

  Biochemical and biophysical research communications 20110325

• Hypermethylation of CpG islands and shores around specific microRNAs and mirtrons is associated with the phenotype and presence of bladder cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110315

• Production of cloned calves by combination treatment of both donor cells and early cloned embryos with 5-aza-2/-deoxycytidine and trichostatin A.

  Theriogenology 20110315

• Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110315

• MBD2 contributes to developmental silencing of the human ε-globin gene.

  Blood cells, molecules & diseases 20110315

• MiR-218 suppresses nasopharyngeal cancer progression through downregulation of survivin and the SLIT2-ROBO1 pathway.

  Cancer research 20110315

• DNA methylation-dependent regulation of TrkA, TrkB, and TrkC genes in human hepatocellular carcinoma.

  Biochemical and biophysical research communications 20110304

• 5-azacytidine, a chemotherapeutic drug, induces TRAIL-mediated apoptosis in mouse thymocytes in vivo.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110301

• MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression.

  Journal of cancer research and clinical oncology 20110301

• In vitro cardiomyogenic potential of human amniotic fluid stem cells.

  Journal of tissue engineering and regenerative medicine 20110301

• Identification of GPX3 epigenetically silenced by CpG methylation in human esophageal squamous cell carcinoma.

  Digestive diseases and sciences 20110301

• Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers.

  Leukemia research 20110301

• Chronic exposure to cigarette smoke condensate in vitro induces epithelial to mesenchymal transition-like changes in human bronchial epithelial cells, BEAS-2B.

  Toxicology in vitro : an international journal published in association with BIBRA 20110301

• An in vivo rat model to study epigenetic control of cell invasion.

  Medical hypotheses 20110301

• Regulation of KEAP1 expression by promoter methylation in malignant gliomas and association with patient's outcome.

  Epigenetics 20110301

• DNA hypomethylation causes bile duct defects in zebrafish and is a distinguishing feature of infantile biliary atresia.

  Hepatology (Baltimore, Md.) 20110301

• New nucleoside analogs for patients with hematological malignancies.

  Expert opinion on investigational drugs 20110301

• Novel agents for the treatment of acute myeloid leukemia in the older patient.

  Journal of the National Comprehensive Cancer Network : JNCCN 20110301

• Hypomethylating agents for urologic cancers.

  Future oncology (London, England) 20110301

• Treatment of myelodysplastic syndromes in elderly patients.

  Advances in therapy 20110301

• Azacytidine for the treatment of myelodysplastic syndromes in the elderly.

  Advances in therapy 20110301

• Azacitidine for the treatment of patients with acute myeloid leukemia with 20%-30% blasts and multilineage dysplasia.

  Advances in therapy 20110301

• Acute myeloblastic leukemia.

  Advances in therapy 20110301

• Cardiomyocyte marker expression in a human lymphocyte cell line using mouse cardiomyocyte extract.

  Human cell 20110301

• Epigenetics in cancer: what's the future?

  Oncology (Williston Park, N.Y.) 20110301

• Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer.

  Molecules and cells 20110227

• Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of DNA methyltransferases 1 and 3a.

  Toxicology and applied pharmacology 20110215

• Noncytotoxic differentiation treatment of renal cell cancer.

  Cancer research 20110215

• Hypomethylating agents and other novel strategies in myelodysplastic syndromes.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210

• Irradiation, cisplatin, and 5-azacytidine upregulate cytomegalovirus promoter in tumors and muscles: implementation of non-invasive fluorescence imaging.

  Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110201

• Functional and epigenetic characterization of the KRT19 gene in renal cell neoplasms.

  DNA and cell biology 20110201

• DNA methyltransferase inhibition may limit cancer cell growth by disrupting ribosome biogenesis.

  Epigenetics 20110201

• Fused-core silica column ultra-performance liquid chromatography-ion trap tandem mass spectrometry for determination of global DNA methylation status.

  Analytical biochemistry 20110201

• Mutation analysis of HIF prolyl hydroxylases (PHD/EGLN) in individuals with features of phaeochromocytoma and renal cell carcinoma susceptibility.

  Endocrine-related cancer 20110201

• Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors.

  Carcinogenesis 20110201

• Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy.

  Biochemical pharmacology 20110201

• Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation.

  Gut 20110201

• Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes.

  Leukemia 20110201

• Successful resolution of acute myelogenous leukemia-associated hemophagocytic lymphohistiocytosis with decitabine.

  Leukemia & lymphoma 20110201

• Differential regulation of the p73 cistrome by mammalian target of rapamycin reveals transcriptional programs of mesenchymal differentiation and tumorigenesis.

  Proceedings of the National Academy of Sciences of the United States of America 20110201

• Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA.

  American journal of hematology 20110201

• Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20110201

• Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

  Arthritis and rheumatism 20110201

• Expression of hypoxic marker CA IX is regulated by site-specific DNA methylation and is associated with the histology of gastric cancer.

  The American journal of pathology 20110201

• DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.

  The American journal of pathology 20110201

• DNA methylation changes following 5-azacitidine treatment in patients with myelodysplastic syndrome.

  Journal of Korean medical science 20110201

• Azacitidine. Poor-prognosis myelodysplasia: promising, but more data needed.

  Prescrire international 20110201

• Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model.

  Genes & cancer 20110201

• Silence of HIN-1 expression through methylation of its gene promoter in gastric cancer.

  World journal of gastroenterology 20110128

• High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).

  Blood 20110120

• Effects of MEK and DNMT inhibitors on arsenic-treated human uroepithelial cells in relation to Cyclin-D1 and p16.

  Toxicology letters 20110115

• Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model.

  Cancer research 20110115

• Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c.

  Biochemical and biophysical research communications 20110114

• Prognostic factors for response and overall survival in 282 patients with higher-risk myelodysplastic syndromes treated with azacitidine.

  Blood 20110113

• Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.

  Mutation research 20110110

• Successive detection of insulin-like growth factor-II bound to receptors on a living cell surface using an AFM.

  Journal of molecular recognition : JMR 20110101

• Azacitidine favorably modulates PSA kinetics correlating with plasma DNA LINE-1 hypomethylation in men with chemonaïve castration-resistant prostate cancer.

  Urologic oncology 20110101

• 3-Deazauridine enhances the antileukemic action of 5-aza-2'-deoxycytidine and targets drug-resistance due to deficiency in deoxycytidine kinase.

  Leukemia research 20110101

• Azacytidine as a novel agent in the treatment of acute lymphoblastic leukemia.

  Leukemia & lymphoma 20110101

• Reduced methyl-CpG protein binding contributing to miR-184 expression in umbilical cord blood CD4+ T-cells.

  Leukemia 20110101

• Epigenetic silencing of somatostatin in gastric cancer.

  Digestive diseases and sciences 20110101

• Hypomethylating agents in acute lymphoblastic leukemia: untapped potential?

  Leukemia & lymphoma 20110101

• Epigenetic regulation of microRNA expression in cancer.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Epigenetic regulation on the 5'-proximal CpG island of human porcine endogenous retrovirus subgroup A receptor 2/GPR172B.

  Microbes and infection 20110101

• Epigenetic modifiers influence lineage commitment of human bone marrow stromal cells: Differential effects of 5-aza-deoxycytidine and trichostatin A.

  Differentiation; research in biological diversity 20110101

• Demethylation of E-cadherin gene in nasopharyngeal carcinoma could serve as a potential therapeutic strategy.

  Journal of biochemistry 20110101

• Demonstration of additional benefit in adding lenalidomide to azacitidine in patients with higher-risk myelodysplastic syndromes.

  American journal of hematology 20110101

• Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma.

  Lung cancer (Amsterdam, Netherlands) 20110101

• FISH in analysis of gamma ray-induced micronuclei formation in barley.

  Journal of applied genetics 20110101

• Out of Africa and into epigenetics: discovering reprogramming drugs.

  Nature cell biology 20110101

• Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.

  Current medicinal chemistry 20110101

• Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors.

  Journal of biomedicine & biotechnology 20110101

• 5-azacytidine enhances proliferation in transplanted rat fetal epiglottis.

  Frontiers in bioscience (Elite edition) 20110101

• Identification of novel DNA methylation inhibitors via a two-component reporter gene system.

  Journal of biomedical science 20110101

• NCCN Clinical Practice Guidelines in Oncology: myelodysplastic syndromes.

  Journal of the National Comprehensive Cancer Network : JNCCN 20110101

• Identification of four potential epigenetic modulators from the NCI structural diversity library using a cell-based assay.

  Journal of biomedicine & biotechnology 20110101

• Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel.

  BMC cancer 20110101

• An engineered cardiac reporter cell line identifies human embryonic stem cell-derived myocardial precursors.

  PloS one 20110101

• Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells.

  Proteome science 20110101

• Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control.

  PloS one 20110101

• Mutation of HIV-1 genomes in a clinical population treated with the mutagenic nucleoside KP1461.

  PloS one 20110101

• Intervention, integration and translation in obesity research: Genetic, developmental and metaorganismal approaches.

  Philosophy, ethics, and humanities in medicine : PEHM 20110101

• Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue.

  Epigenetics & chromatin 20110101

• Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia.

  PloS one 20110101

• Abiotic stress and induced DNA hypomethylation cause interphase chromatin structural changes in rice rDNA loci.

  Cytogenetic and genome research 20110101

• The role of HDACs inhibitors in childhood and adolescence acute leukemias.

  Journal of biomedicine & biotechnology 20110101

• Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice.

  BMC cancer 20110101

• Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.

  BMC cancer 20110101

• Pretreatment of rat bone marrow mesenchymal stem cells with a combination of hypergravity and 5-azacytidine enhances therapeutic efficacy for myocardial infarction.

  Biotechnology progress 20110101

• Transcriptional repressive H3K9 and H3K27 methylations contribute to DNMT1-mediated DNA methylation recovery.

  PloS one 20110101

• Dermal fibroblasts display similar phenotypic and differentiation capacity to fat-derived mesenchymal stem cells, but differ in anti-inflammatory and angiogenic potential.

  Vascular cell 20110101

• Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells.

  PloS one 20110101

• Functional and sequence analysis of human neuroglobin gene promoter region.

  Biochimica et biophysica acta 20110101

• Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia.

  Stem cell research & therapy 20110101

• Induction of cyclooxygenase-2 expression by hepatitis B virus depends on demethylation-associated recruitment of transcription factors to the promoter.

  Virology journal 20110101

• Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.

  PloS one 20110101

• Genome-wide assessment of imprinted expression in human cells.

  Genome biology 20110101

• [The role of promoter CpG islands methylation of leptin gene in osteoarthritis].

  Zhonghua nei ke za zhi 20110101

• Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these cells promotes nerve healing and axon growth de novo.

  PloS one 20110101

• [Progress in research on DNA methylation and laryngeal carcinoma].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20110101

• Proximity ligation in situ assay for monitoring the global DNA methylation in cells.

  BMC biotechnology 20110101

• [Study of RASSF1A expression and promoter demethylation in Hep-2 cell line].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20110101

• A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability.

  PloS one 20110101

• Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663.

  Journal of hematology & oncology 20110101

• Epigenetic regulation of cancer-associated genes in ovarian cancer.

  International journal of molecular sciences 20110101

• Epigenetic regulation of satellite cell activation during muscle regeneration.

  Stem cell research & therapy 20110101

• Epigenetic inactivation of the miR-124-1 in haematological malignancies.

  PloS one 20110101

• CpG island methylation in colorectal cancer: past, present and future.

  Pathology research international 20110101

• Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis.

  Sarcoma 20110101

• DNA methyltransferase controls stem cell aging by regulating BMI1 and EZH2 through microRNAs.

  PloS one 20110101

• Cardiac differentiation of pluripotent stem cells.

  Stem cells international 20110101

• Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications.

  BMC medicine 20110101

• 5-azacytidine in chronic myelomonocytic leukemia: case report and review of literature.

  Mediterranean journal of hematology and infectious diseases 20110101

• Interpreting clinical assays for histone deacetylase inhibitors.

  Cancer management and research 20110101

• SLIT2 is epigenetically silenced in ovarian cancers and suppresses growth when activated.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• Myelodysplastic syndrome and histone deacetylase inhibitors: 'to be or not to be acetylated'?

  Journal of biomedicine & biotechnology 20110101

• Allele-specific, age-dependent and BMI-associated DNA methylation of human MCHR1.

  PloS one 20110101

• Aberrant methylation of N-methyl-D-aspartate receptor type 2B (NMDAR2B) in non-small cell carcinoma.

  BMC cancer 20110101

• SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation.

  BMC cancer 20110101

• Epigenetic changes in cancer.

  F1000 biology reports 20110101

• Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter.

  BMC cancer 20110101

• Changes in global gene expression in response to chemical and genetic perturbation of chromatin structure.

  PloS one 20110101

• Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm.

  PloS one 20110101

• Expression analysis of genes involved in epigenetic regulation and apoptosis in human malignant haematopoietic cell lines treated with 5-azacytidine.

  Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20110101

• Molecular carcinogenesis of hepatocellular carcinoma and intrahepatic cholangiocarcinoma: one step closer to personalized medicine?

  Cell & bioscience 20110101

• Isolation of fidelity variants of RNA viruses and characterization of virus mutation frequency.

  Journal of visualized experiments : JoVE 20110101

• Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells.

  PloS one 20110101

• Vitamin A and retinoid derivatives for lung cancer: a systematic review and meta analysis.

  PloS one 20110101

• Expression of MAGE-C1/CT7 and MAGE-C2/CT10 predicts lymph node metastasis in melanoma patients.

  PloS one 20110101

• Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis.

  Clinical and experimental gastroenterology 20110101

• Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia.

  PloS one 20110101

• Therapeutic strategies to enhance the anticancer efficacy of histone deacetylase inhibitors.

  Journal of biomedicine & biotechnology 20110101

• Involvement of phosphatases in proliferation, maturation, and hemoglobinization of developing erythroid cells.

  Journal of signal transduction 20110101

• Improvement of cardiac function in mouse myocardial infarction after transplantation of epigenetically-modified bone marrow progenitor cells.

  PloS one 20110101

• Stem Cell Therapy in Acute Myocardial Infarction: A Pot of Gold or Pandora's Box.

  Stem cells international 20110101

• Cellular Reprogramming toward the Erythroid Lineage.

  International journal of cell biology 20110101

• Trichostatin A selectively suppresses the cold-induced transcription of the ZmDREB1 gene in maize.

  PloS one 20110101

• Location-specific epigenetic regulation of the metallothionein 3 gene in esophageal adenocarcinomas.

  PloS one 20110101

• Azacitidine.

  Report on carcinogens : carcinogen profiles 20110101

• Long term transcriptional reactivation of epigenetically silenced genes in colorectal cancer cells requires DNA hypomethylation and histone acetylation.

  PloS one 20110101

• Methylation-associated down-regulation of RASSF1A and up-regulation of RASSF1C in pancreatic endocrine tumors.

  BMC cancer 20110101

• Epigenetic therapy for breast cancer.

  International journal of molecular sciences 20110101

• DNA demethylation is superior to histone acetylation for reactivating cancer-associated genes in ovarian cancer cells.

  Molecular medicine reports 20110101

• Gene network inference and biochemical assessment delineates GPCR pathways and CREB targets in small intestinal neuroendocrine neoplasia.

  PloS one 20110101

• Mechanisms of resistance to decitabine in the myelodysplastic syndrome.

  PloS one 20110101

• DNA methylation of SPARC and chronic low back pain.

  Molecular pain 20110101

• The Ethanol Extract of Fructus trichosanthis Promotes Fetal Hemoglobin Production via p38 MAPK Activation and ERK Inactivation in K562 Cells.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells.

  PloS one 20110101

• Effects of the demethylating agent, 5-azacytidine, on expression of the kallikrein-kinin genes in carcinoma cells of the lung and pleura.

  Pathology research international 20110101

• DNA demethylation in PD-1 gene promoter induced by 5-azacytidine activates PD-1 expression on Molt-4 cells.

  Cellular immunology 20110101

• Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells.

  PloS one 20110101

• Inhibition of DNA methylation in somatic cells.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Current findings for recurring mutations in acute myeloid leukemia.

  Journal of hematology & oncology 20110101

• Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma.

  Journal of translational medicine 20110101

• Hydroxyurea therapy mobilises arachidonic Acid from inner cell membrane aminophospholipids in patients with homozygous sickle cell disease.

  Journal of lipids 20110101

• MicroRNAs in rhabdomyosarcoma: pathogenetic implications and translational potentiality.

  Molecular cancer 20110101

• Systematic in-vitro evaluation of the NCI/NIH Developmental Therapeutics Program Approved Oncology Drug Set for the identification of a candidate drug repertoire for MLL-rearranged leukemia.

  OncoTargets and therapy 20110101

• Generation of reactive oxygen species during apoptosis induced by DNA-damaging agents and/or histone deacetylase inhibitors.

  Oxidative medicine and cellular longevity 20110101

• Mechanisms of mycotoxin-induced neurotoxicity through oxidative stress-associated pathways.

  International journal of molecular sciences 20110101

• Promoting illiteracy in epigenetics: an emerging therapeutic strategy.

  Current chemical genomics 20110101

• Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression.

  PloS one 20110101

• Nuclear reprogramming in mouse primordial germ cells: epigenetic contribution.

  Stem cells international 20110101

• Integrin alpha9 (ITGA9) expression and epigenetic silencing in human breast tumors.

  Cell adhesion & migration 20110101

• GSTP1 DNA methylation and expression status is indicative of 5-aza-2'-deoxycytidine efficacy in human prostate cancer cells.

  PloS one 20110101

• Market Access Agreements for pharmaceuticals in Europe: diversity of approaches and underlying concepts.

  BMC health services research 20110101

• Methylation changes associated with early maturation stages in the Atlantic salmon.

  BMC genetics 20110101

• Loss of glucocorticoid receptor expression by DNA methylation prevents glucocorticoid induced apoptosis in human small cell lung cancer cells.

  PloS one 20110101

• Age-related changes in rat bone-marrow mesenchymal stem cell plasticity.

  BMC cell biology 20110101

• miRNAs differentially expressed in prostate cancer cell lines after soy treatment.

  In vivo (Athens, Greece) 20110101

• HDAC6 regulates LPS-tolerance in astrocytes.

  PloS one 20110101

• Recent advance in antigen-specific immunotherapy for acute myeloid leukemia.

  Clinical & developmental immunology 20110101

• Systemic vasculitis with prolonged pyrexia, recurrent facial urticaria, skin nodules, pleural effusions and venous thrombosis: an unusual presentation of an uncommon disease.

  German medical science : GMS e-journal 20110101

• The role of epigenetic variation in the pathogenesis of systemic lupus erythematosus.

  Arthritis research & therapy 20110101

• Developmental mechanisms in articular cartilage degradation in osteoarthritis.

  Arthritis 20110101

• Decitabine immunosensitizes human gliomas to NY-ESO-1 specific T lymphocyte targeting through the Fas/Fas ligand pathway.

  Journal of translational medicine 20110101

• Zebularine suppresses TGF-beta-induced lens epithelial cell-myofibroblast transdifferentiation by inhibiting MeCP2.

  Molecular vision 20110101

• Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas.

  PloS one 20110101

• Manganese superoxide dismutase: guardian of the powerhouse.

  International journal of molecular sciences 20110101

• Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.

  PloS one 20110101

• Epigenetics in breast cancer: what's new?

  Breast cancer research : BCR 20110101

• Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms.

  Journal of translational medicine 20110101

• A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome.

  Journal of hematology & oncology 20110101

• Arsenic, cadmium and neuron specific enolase (ENO2, γ-enolase) expression in breast cancer.

  Cancer cell international 20110101

• Uses of cardiomyocytes generated from induced pluripotent stem cells.

  Stem cell research & therapy 20110101

• Therapy-related myeloid malignancies in myeloma.

  Mediterranean journal of hematology and infectious diseases 20110101

• Mechanisms of neurotoxicity induced in the developing brain of mice and rats by DNA-damaging chemicals.

  The Journal of toxicological sciences 20110101

• Human cardiac stem cells isolated from atrial appendages stably express c-kit.

  PloS one 20110101

• Epigenetic mechanisms of pulmonary hypertension.

  Pulmonary circulation 20110101

• New ways to use DNA methyltransferase inhibitors for the treatment of myelodysplastic syndrome.

  Hematology. American Society of Hematology. Education Program 20110101

• Modeling neurological disorders by human induced pluripotent stem cells.

  Journal of biomedicine & biotechnology 20110101

• Cigarette smoking and p16INK4α gene promoter hypermethylation in non-small cell lung carcinoma patients: a meta-analysis.

  PloS one 20110101

• Epigenetics in prostate cancer.

  Prostate cancer 20110101

• Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses.

  PloS one 20110101

• Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cells.

  PloS one 20110101

• Effects of 5-azacytidine and trichostatin A on dendritic cell maturation.

  Journal of biological regulators and homeostatic agents 20110101

• Fetal hemoglobin reactivation and cell engineering in the treatment of sickle cell anemia.

  Journal of blood medicine 20110101

• Romidepsin in the treatment of cutaneous T-cell lymphoma.

  Journal of blood medicine 20110101

• Development of an oral form of azacytidine: 2'3'5'triacetyl-5-azacytidine.

  Chemotherapy research and practice 20110101

• [AntiEBV activity of 6-azacytidine and its derivatives].

  Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20110101

• Methylation of secreted frizzled related protein gene in acute leukemia patients in China.

  Asian Pacific journal of cancer prevention : APJCP 20110101

• [Spontaneous and induced myogenesis in cell culture from rat fetal liver].

  Tsitologiia 20110101

• Impact of DNA methylation on trophoblast function.

  Clinical epigenetics 20110101

• Ribavirin restores ESR1 gene expression and tamoxifen sensitivity in ESR1 negative breast cancer cell lines.

  Clinical epigenetics 20110101

• Suffocating cancer: hypoxia-associated epimutations as targets for cancer therapy.

  Clinical epigenetics 20110101

• Proliferation inhibition, cell cycle arrest and apoptosis induced in HL-60 cells by a natural diterpene ester from Daphne mucronata.

  Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

• Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers.

  Frontiers in oncology 20110101

• Cytomegalovirus colitis following azacitidine therapy.

  The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 20110101

• Cytogenetic effect of 5-azacytidine in patients with hematological malignancies.

  Revista brasileira de hematologia e hemoterapia 20110101

• Sequential treatment of CD34+ cells from patients with primary myelofibrosis with chromatin-modifying agents eliminate JAK2V617F-positive NOD/SCID marrow repopulating cells.

  Blood 20101223

• [Myeloproliferative/myelodysplastic syndromes].

  La Revue du praticien 20101220

• [Current management of myelodysplastic syndromes].

  La Revue du praticien 20101220

• The role of the DNA hypermethylating agent Budesonide in the decatenating activity of DNA topoisomerase II.

  Mutation research 20101210

• Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repair.

  Circulation 20101207

• Olfactomedin 4 is a novel target gene of retinoic acids and 5-aza-2'-deoxycytidine involved in human myeloid leukemia cell growth, differentiation, and apoptosis.

  Blood 20101202

• DNA methylation and carcinogenesis of PRDM5 in cervical cancer.

  Journal of cancer research and clinical oncology 20101201

• Expression, epigenetic regulation, and humoral immunogenicity of cancer-testis antigens in chronic myeloid leukemia.

  Leukemia research 20101201

• Effects of azacitidine compared with conventional care regimens in elderly (≥ 75 years) patients with higher-risk myelodysplastic syndromes.

  Critical reviews in oncology/hematology 20101201

• Reprogramming of human umbilical cord stromal mesenchymal stem cells for myogenic differentiation and muscle repair.

  Stem cell reviews 20101201

• Maintenance therapy with low-dose azacitidine after allogeneic hematopoietic stem cell transplantation for recurrent acute myelogenous leukemia or myelodysplastic syndrome: a dose and schedule finding study.

  Cancer 20101201

• A role for Gcn5 in cardiomyocyte differentiation of rat mesenchymal stem cells.

  Molecular and cellular biochemistry 20101201

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Decitabine in myelodysplastic syndromes and chronic myelomonocytic leukemia: Argentinian/South Korean multi-institutional clinical experience.

  Leukemia & lymphoma 20101201

• Prodrugs of aza nucleosides based on proton transfer reaction.

  Journal of computer-aided molecular design 20101201

• Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms.

  Hepatology (Baltimore, Md.) 20101201

• Loss of heterozygosity and DNA methylation affect germline fibroblast growth factor receptor 4 polymorphism to direct allelic selection in breast cancer.

  The American journal of pathology 20101201

• A phase II study of low dose intravenous clofarabine for elderly patients with myelodysplastic syndrome who have failed 5-azacytidine.

  Leukemia & lymphoma 20101201

• Pharmacologic induction of fetal hemoglobin production.

  Hematology/oncology clinics of North America 20101201

• Analysis of genome-wide methylation and gene expression induced by 5-aza-2'-deoxycytidine identifies BCL2L10 as a frequent methylation target in acute myeloid leukemia.

  Leukemia & lymphoma 20101201

• Tissue-specific expression of IL-15RA alternative splicing transcripts and its regulation by DNA methylation.

  European cytokine network 20101201

• Deactylase inhibition in myeloproliferative neoplasms.

  Investigational new drugs 20101201

• Histone deacetylase inhibitors in Hodgkin lymphoma.

  Investigational new drugs 20101201

• Has there been progress in the treatment of older patients with acute myeloid leukemia?

  Best practice & research. Clinical haematology 20101201

• The DAC system and associations with acute leukemias and myelodysplastic syndromes.

  Investigational new drugs 20101201

• Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect.

  Investigational new drugs 20101201

• [5-azacytidine suppresses K562 cell line proliferation by down-regulation of miR-17-19b].

  Zhongguo shi yan xue ye xue za zhi 20101201

• Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer.

  Anticancer research 20101201

• Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.

  Anticancer research 20101201

• Cloning and characterization of a novel gene with alternative splicing in murine mesenchymal stem cell line C3H/10T1/2 by gene trap screening.

  BMB reports 20101201

• Alphabet soup: RAEB, HMA, DOE, and AFOP.

  Medicine and health, Rhode Island 20101201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20101201

• Epigenetic repression of SATB1 by polycomb group protein EZH2 in epithelial cells.

  Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20101201

• Economic analysis of decitabine versus best supportive care in the treatment of intermediate- and high-risk myelodysplastic syndromes from a US payer perspective.

  Clinical therapeutics 20101201

• Downregulation of miR-205 and miR-31 confers resistance to chemotherapy-induced apoptosis in prostate cancer cells.

  Cell death & disease 20101201

• Cytosine methyltransferases as tumor markers.

  Current genomics 20101201

• Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.

  Experimental cell research 20101115

• Long-term persistence of acquired resistance to 5-fluorouracil in the colon cancer cell line SW620.

  Experimental cell research 20101115

• Epigenetic silencing of beta-spectrin, a TGF-beta signaling/scaffolding protein in a human cancer stem cell disorder: Beckwith-Wiedemann syndrome.

  The Journal of biological chemistry 20101112

• Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM).

  Blood 20101111

• Practical use of azacitidine in higher-risk myelodysplastic syndromes: an expert panel opinion.

  Leukemia research 20101101

• Epigenetic regulation of miR-196b expression in gastric cancer.

  Genes, chromosomes & cancer 20101101

• Epigenetic inactivation of the tumor suppressor gene RIZ1 in hepatocellular carcinoma involves both DNA methylation and histone modifications.

  Journal of hepatology 20101101

• Promoter hypermethylation of progesterone receptor isoform B (PR-B) in adenomyosis and its rectification by a histone deacetylase inhibitor and a demethylation agent.

  Reproductive sciences (Thousand Oaks, Calif.) 20101101

• Decitabine increases fetal hemoglobin in Papio anubis by increasing γ-globin gene transcription.

  Experimental hematology 20101101

• Epigenetic alteration of the NF-κB-inducing kinase (NIK) gene is involved in enhanced NIK expression in basal-like breast cancer.

  Cancer science 20101101

• Importance of the tmRNA system for cell survival when transcription is blocked by DNA-protein cross-links.

  Molecular microbiology 20101101

• Aberrant demethylation of the recoverin gene is involved in the aberrant expression of recoverin in cancer cells.

  Experimental dermatology 20101101

• The effect of DNA methylation inhibitor 5-Aza-2'-deoxycytidine on human endometrial stromal cells.

  Human reproduction (Oxford, England) 20101101

• Targeting DNA methylation for epigenetic therapy.

  Trends in pharmacological sciences 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Myelodysplastic syndromes--many new drugs, little therapeutic progress.

  Mayo Clinic proceedings 20101101

• Resilience to social stress coincides with functional DNA methylation of the Crf gene in adult mice.

  Nature neuroscience 20101101

• Intratracheally administered 5-azacytidine is effective against orthotopic human lung cancer xenograft models and devoid of important systemic toxicity.

  Clinical lung cancer 20101101

• Claudin-7 down-regulation is an important feature in oral squamous cell carcinoma.

  Histopathology 20101101

• Altered DNA methylation in leukocytes with trisomy 21.

  PLoS genetics 20101101

• [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20101101

• Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription.

  Oncogene 20101028

• Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy.

  Blood 20101028

• The novel human endogenous retrovirus-related gene, psiTPTE22-HERV, is silenced by DNA methylation in cancers.

  International journal of cancer 20101015

• Cardiomyocyte differentiation of rat bone marrow multipotent progenitor cells is associated with downregulation of Oct-4 expression.

  Tissue engineering. Part A 20101001

• Epigenetically altered wound healing in keloid fibroblasts.

  The Journal of investigative dermatology 20101001

• Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells.

  Journal of molecular medicine (Berlin, Germany) 20101001

• Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study.

  Pediatric blood & cancer 20101001

• Proteome analysis of rat bone marrow mesenchymal stem cell differentiation.

  Journal of proteome research 20101001

• DNA methylation and cellular reprogramming.

  Trends in cell biology 20101001

• Successive silencing of tandem reporter genes in potato (Solanum tuberosum) over 5 years of vegetative propagation.

  Annals of botany 20101001

• Myelodysplastic syndromes in older adults.

  Clinical journal of oncology nursing 20101001

• Methylation-mediated silencing of TMS1 in pancreatic cancer and its potential contribution to chemosensitivity.

  Anticancer research 20101001

• Fidelity variants of RNA dependent RNA polymerases uncover an indirect, mutagenic activity of amiloride compounds.

  PLoS pathogens 20101001

• [Expression, genetic and epigenetic alterations of LTF gene in nasopharyngeal carcinoma cell lines].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101001

• Effect of fluid shear stress on cardiomyogenic differentiation of rat bone marrow mesenchymal stem cells.

  Archives of medical research 20101001

• Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid.

  Cell death & disease 20101001

• Epigenetic regulation of neonatal cardiomyocytes differentiation.

  Biochemical and biophysical research communications 20100917

• Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia.

  Blood 20100916

• Effect of 5-aza-2-deoxycytidine microinjecting into hippocampus and prelimbic cortex on acquisition and retrieval of cocaine-induced place preference in C57BL/6 mice.

  European journal of pharmacology 20100910

• Determination of hypersensitivity to genotoxic agents among Escherichia coli single gene knockout mutants.

  DNA repair 20100904

• Is there an association between 5-azacitidine and ototoxicity?

  Journal of clinical pharmacology 20100901

• Demethylating agent 5-aza-2-deoxycytidine enhances susceptibility of breast cancer cells to anticancer agents.

  Molecular and cellular biochemistry 20100901

• Trex-1 deficiency in rheumatoid arthritis synovial fibroblasts.

  Arthritis and rheumatism 20100901

• Promotion of human adipose-derived stem cell proliferation mediated by exogenous nucleosides.

  Cell biology international 20100901

• A phase 1 and pharmacodynamic study of decitabine in combination with carboplatin in patients with recurrent, platinum-resistant, epithelial ovarian cancer.

  Cancer 20100901

• Azacitidine for treatment of patients with myelodysplastic syndromes (MDS): practical recommendations of the German MDS Study Group.

  Annals of hematology 20100901

• Exploiting drug repositioning for discovery of a novel HIV combination therapy.

  Journal of virology 20100901

• Effects of 17beta-estradiol and xenoestrogens on mouse embryonic stem cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20100901

• Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer.

  Carcinogenesis 20100901

• Chromatin remodeling is required for gene reactivation after decitabine-mediated DNA hypomethylation.

  Cancer research 20100901

• Demethylation treatment restores hic1 expression and impairs aggressiveness of head and neck squamous cell carcinoma.

  Oral oncology 20100901

• Streptozotocin-induced diabetic rat-derived bone marrow mesenchymal stem cells have impaired abilities in proliferation, paracrine, antiapoptosis, and myogenic differentiation.

  Transplantation proceedings 20100901

• [Current treatment options for myelodysplastic syndromes].

  Deutsche medizinische Wochenschrift (1946) 20100901

• Transplantation of 5-azacytidine treated cardiac fibroblasts improves cardiac function of infarct hearts in rats.

  Chinese medical journal 20100901

• Genomic and epigenomic instability, fragile sites, schizophrenia and autism.

  Current genomics 20100901

• Treatment of myelodysplastic syndrome transforming into acute myelogenous leukemia with azacytidine: a retrospective study from cancer centre in northern India.

  Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion 20100901

• The mechanism underlying the differentiation of human umbilical cord-derived mesenchymal stem cells into myocardial cells induced by 5-azacytidine.

  Indian journal of medical sciences 20100901

• Effects of cardiotrophin-1 on differentiation and maturation of rat bone marrow mesenchymal stem cells induced with 5-azacytidine in vitro.

  International journal of cardiology 20100820

• Up-regulation of connexin 32 gene by 5-aza-2'-deoxycytidine enhances vinblastine-induced cytotoxicity in human renal carcinoma cells via the activation of JNK signalling.

  Biochemical pharmacology 20100815

• Outcome of patients with myelodysplastic syndrome after failure of decitabine therapy.

  Cancer 20100815

• Chronic prenatal hypoxia induces epigenetic programming of PKC{epsilon} gene repression in rat hearts.

  Circulation research 20100806

• Genomic screening for genes upregulated by demethylation revealed novel targets of epigenetic silencing in breast cancer.

  Breast cancer research and treatment 20100801

• Azacytidine treatment after discontinuation of immunosuppressants in patients with myelodysplastic syndrome and relapse after allo-SCT at a single center.

  Bone marrow transplantation 20100801

• 5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.

  The Prostate 20100801

• Functional modulation of IGF-binding protein-3 expression in melanoma.

  The Journal of investigative dermatology 20100801

• Clinical advances in hypomethylating agents targeting epigenetic pathways.

  Current cancer drug targets 20100801

• Management and supportive care measures for adverse events in patients with myelodysplastic syndromes treated with azacitidine*.

  European journal of haematology 20100801

• Caution using hypomethylating agents in myelodysplasia or myeloid leukemia with complex cytogenetics.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100801

• Pharmacotherapy of myelodysplastic syndromes.

  Expert opinion on pharmacotherapy 20100801

• Maintenance treatment with azacytidine for patients with high-risk myelodysplastic syndromes (MDS) or acute myeloid leukaemia following MDS in complete remission after induction chemotherapy.

  British journal of haematology 20100801

• Therapy with azanucleosides for myelodysplastic syndromes.

  Nature reviews. Clinical oncology 20100801

• S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer.

  The American journal of pathology 20100801

• Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance.

  The Journal of pathology 20100801

• CpG hypermethylation of human four-and-a-half LIM domains 1 contributes to migration and invasion activity of human bladder cancer.

  International journal of molecular medicine 20100801

• Validation of a novel statistical model for assessing the synergy of combined-agent cancer chemoprevention.

  Cancer prevention research (Philadelphia, Pa.) 20100801

• Identification of novel methylation markers in hepatocellular carcinoma using a methylation array.

  Journal of Korean medical science 20100801

• Combinations of DNA methyltransferase and histone deacetylase inhibitors induce DNA damage in small cell lung cancer cells: correlation of resistance with IFN-stimulated gene expression.

  Molecular cancer therapeutics 20100801

• Fetal globin gene inducers: novel agents and new potential.

  Annals of the New York Academy of Sciences 20100801

• CTCF prevents the epigenetic drift of EBV latency promoter Qp.

  PLoS pathogens 20100801

• A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.

  PLoS pathogens 20100801

• [Study on promoter methylation status of E-cadherin gene in nasopharyngeal carcinoma cell lines].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20100801

• DNA instability at chromosomal fragile sites in cancer.

  Current genomics 20100801

• Current and future management options for myelodysplastic syndromes.

  Drugs 20100730

• Epigenetic regulation of vitamin D 24-hydroxylase/CYP24A1 in human prostate cancer.

  Cancer research 20100715

• MAD2 downregulation in hypoxia is independent of promoter hypermethylation.

  Cell cycle (Georgetown, Tex.) 20100715

• The functional significance of microRNA-145 in prostate cancer.

  British journal of cancer 20100713

• In vivo administration of hypomethylating agents mitigate graft-versus-host disease without sacrificing graft-versus-leukemia.

  Blood 20100708

• Rapid determination of AKAP12 promoter methylation levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: application in colorectal cancer.

  Clinica chimica acta; international journal of clinical chemistry 20100704

• Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance.

  Annals of oncology : official journal of the European Society for Medical Oncology 20100701

• Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis.

  Immunology 20100701

• VDR microRNA expression and epigenetic silencing of vitamin D signaling in melanoma cells.

  The Journal of steroid biochemistry and molecular biology 20100701

• Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells.

  Pancreas 20100701

• Establishment and characterization of multi-drug resistant, prostate carcinoma-initiating stem-like cells from human prostate cancer cell lines 22RV1.

  Molecular and cellular biochemistry 20100701

• Sequential loss of cell cycle checkpoint control contributes to malignant transformation of murine embryonic fibroblasts induced by 20-methylcholanthrene.

  Journal of cellular physiology 20100701

• Predictive value of pretreatment risk group and baseline LDH levels in MDS patients receiving azacitidine treatment.

  Annals of hematology 20100701

• Vectorial transport of nucleoside analogs from the apical to the basolateral membrane in double-transfected cells expressing the human concentrative nucleoside transporter hCNT3 and the export pump ABCC4.

  Drug metabolism and disposition: the biological fate of chemicals 20100701

• Modulation of E-cadherin expression by K-Ras; involvement of DNA methyltransferase-3b.

  Carcinogenesis 20100701

• The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells.

  Leukemia research 20100701

• DNA methylation-related vitamin D receptor insensitivity in breast cancer.

  Cancer biology & therapy 20100701

• Epigenetic regulation of photoperiodic flowering.

  Plant signaling & behavior 20100701

• Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation.

  British journal of haematology 20100701

• WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations.

  Leukemia 20100701

• Early growth response-1 induces and enhances vascular endothelial growth factor-A expression in lung cancer cells.

  The American journal of pathology 20100701

• DNA methylation of interferon regulatory factors in gastric cancer and noncancerous gastric mucosae.

  Cancer science 20100701

• Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy.

  Molecular cancer research : MCR 20100701

• [Differentiation of 5-azacytidine-induced bone marrow stromal stem cells transduced with hepatocyte growth factor gene].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100701

• Screening for methylation-silenced genes in acute myeloid leukemia HL-60 cell line by a quantitative proteomic approach.

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20100701

• [Experimental study on effect of monocyte chemoattractant protein 1 on migration of induced and differentiated mouse bone marrow mesenchymal stem cells in vitro].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20100701

• Promoter hypomethylation contributes to the expression of MUC3A in cancer cells.

  Biochemical and biophysical research communications 20100625

• Eleventh biannual report of the Cochrane Haematological Malignancies Group: Focus on Hodgkin lymphoma.

  Journal of the National Cancer Institute 20100616

• Downregulation of WIF-1 by hypermethylation in astrocytomas.

  Acta biochimica et biophysica Sinica 20100615

• Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting.

  Blood 20100610

• Methylation of PARP-1 promoter involved in the regulation of benzene-induced decrease of PARP-1 mRNA expression.

  Toxicology letters 20100602

• 5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1.

  Medical oncology (Northwood, London, England) 20100601

• Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation.

  Molecular biology reports 20100601

• Induction of apoptosis of non-small cell lung cancer by a methylated oligonucleotide targeting survivin gene.

  Cancer gene therapy 20100601

• Epigenetic therapy in myelodysplastic syndromes.

  European journal of haematology 20100601

• Role of Ucp1 enhancer methylation and chromatin remodelling in the control of Ucp1 expression in murine adipose tissue.

  Diabetologia 20100601

• Quantitative assessment of AKAP12 promoter methylation in colorectal cancer using methylation-sensitive high resolution melting: Correlation with Duke's stage.

  Cancer biology & therapy 20100601

• Pharmacoepigenetics in heart failure.

  Current heart failure reports 20100601

• DNA methylation contributes to loss in productivity of monoclonal antibody-producing CHO cell lines.

  Journal of biotechnology 20100601

• Epigenetic mechanisms of promigratory chemokine CXCL14 regulation in human prostate cancer cells.

  Cancer research 20100601

• Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

  Molecular cancer therapeutics 20100601

• Feasibility of therapy with hypomethylating agents in patients with renal insufficiency.

  Clinical lymphoma, myeloma & leukemia 20100601

• An update on the treatment of myelodysplastic syndromes.

  Clinical journal of oncology nursing 20100601

• Induced differentiation of adipose-derived stromal cells into myoblasts.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20100601

• Function and regulatory mechanisms of the candidate tumor suppressor receptor protein tyrosine phosphatase gamma (PTPRG) in breast cancer cells.

  Anticancer research 20100601

• DNA and histone deacetylases as targets for neuroblastoma treatment.

  Interdisciplinary toxicology 20100601

• Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum.

  Journal of natural products 20100528

• Effect of 5-aza-2'-deoxycytidine on immune-associated proteins in exosomes from hepatoma.

  World journal of gastroenterology 20100521

• [The relationship between the TSLC1 silencing and DNA methylation in human lung cancer cells].

  Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100520

• Assessing the DNA methylation status of single cells with the comet assay.

  Analytical biochemistry 20100515

• Progression to metastatic stage in a cellular model of prostate cancer is associated with methylation of the androgen receptor gene and transcriptional suppression of the insulin-like growth factor-I receptor gene.

  Experimental cell research 20100515

• 5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis.

  Bone marrow transplantation 20100501

• FOXE1 is a target for aberrant methylation in cutaneous squamous cell carcinoma.

  The British journal of dermatology 20100501

• Role of histone modifications and DNA methylation in the regulation of O6-methylguanine-DNA methyltransferase gene expression in human stomach cancer cells.

  Cancer investigation 20100501

• Generation of antigen-presenting cells from tumor-infiltrated CD11b myeloid cells with DNA demethylating agent 5-aza-2'-deoxycytidine.

  Cancer immunology, immunotherapy : CII 20100501

• Neutrophilic eccrine hidradenitis associated with decitabine.

  Leukemia research 20100501

• Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis.

  Carcinogenesis 20100501

• Exposure to cardiomyogenic stimuli fails to transdifferentiate human umbilical cord blood-derived mesenchymal stem cells.

  Basic research in cardiology 20100501

• Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation.

  Genes, chromosomes & cancer 20100501

• Aberrant methylation impairs low density lipoprotein receptor-related protein 1B tumor suppressor function in gastric cancer.

  Genes, chromosomes & cancer 20100501

• Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20100501

• Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium.

  American journal of respiratory and critical care medicine 20100501

• Epigenetically regulated clonal heritability of CTA expression profiles in human melanoma.

  Journal of cellular physiology 20100501

• TWIST1 hypermethylation is observed frequently in colorectal tumors and its overexpression is associated with unfavorable outcomes in patients with colorectal cancer.

  Genes, chromosomes & cancer 20100501

• Phase I combination trial of lenalidomide and azacitidine in patients with higher-risk myelodysplastic syndromes.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501

• 5-Aza-2'-deoxycytidine treatment induces skeletal myogenic differentiation of mouse dental pulp stem cells.

  Archives of oral biology 20100501

• Altered DNA methylation is associated with docetaxel resistance in human breast cancer cells.

  International journal of oncology 20100501

• [Epigenetic therapy in myelodysplastic syndromes (MDS). Treatment with DNA methyltransferase inhibitors].

  Pharmazie in unserer Zeit 20100501

• Advances in the management of acute myeloid leukemia in older adult patients.

  Oncology nursing forum 20100501

• S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth.

  Molecular cancer therapeutics 20100501

• Delivery of 5-azacytidine to human cancer cells by elaidic acid esterification increases therapeutic drug efficacy.

  Molecular cancer therapeutics 20100501

• Azacitidine for the treatment of myelodysplastic syndrome, chronic myelomonocytic leukaemia and acute myeloid leukaemia.

  Health technology assessment (Winchester, England) 20100501

• Enhancement of cardiomyocyte differentiation from human embryonic stem cells.

  Science China. Life sciences 20100501

• Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome.

  Oncotarget 20100501

• Epigenetic repression of PDZ-LIM domain-containing protein 2: implications for the biology and treatment of breast cancer.

  The Journal of biological chemistry 20100416

• Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines.

  Toxicology letters 20100415

• Effects of a novel DNA methyltransferase inhibitor zebularine on human breast cancer cells.

  Breast cancer research and treatment 20100401

• CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.

  Breast cancer research and treatment 20100401

• Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil.

  Annals of hematology 20100401

• Efficacy of a 3-day, low-dose treatment with 5-azacytidine followed by donor lymphocyte infusions in older patients with acute myeloid leukemia or chronic myelomonocytic leukemia relapsed after allografting.

  Bone marrow transplantation 20100401

• Effects of decitabine on the expression of selected endogenous control genes in human breast cancer cells.

  Molecular and cellular probes 20100401

• Effects of 5-azacytidine on lymphocyte-metaphases of Creole cows carrying the rob(1;29).

  Research in veterinary science 20100401

• Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401

• Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100401

• Differentiation of human adipose-derived stem cells into beating cardiomyocytes.

  Journal of cellular and molecular medicine 20100401

• CpG methylation attenuates Sp1 and Sp3 binding to the human extracellular superoxide dismutase promoter and regulates its cell-specific expression.

  Free radical biology & medicine 20100401

• Inheritance of acquired traits in plants: reinstatement of Lamarck.

  Plant signaling & behavior 20100401

• In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine.

  Cancer chemotherapy and pharmacology 20100401

• Epigenetic mediated transcriptional activation of PARP-1 participates in silica-associated malignant transformation of human bronchial epithelial cells.

  Toxicology letters 20100401

• Molecular genetic and epigenetic analysis of NCX2/SLC8A2 at 19q13.3 in human gliomas.

  Neuropathology and applied neurobiology 20100401

• Prolonged survival with improved tolerability in higher-risk myelodysplastic syndromes: azacitidine compared with low dose ara-C.

  British journal of haematology 20100401

• The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study.

  Urology 20100401

• Expression and regulation mechanisms of Sonic Hedgehog in breast cancer.

  Cancer science 20100401

• Porcupine expression is associated with the expression of S100P and other cancer-related molecules in non-small cell lung carcinoma.

  International journal of oncology 20100401

• Identification of hypermethylated genes associated with cisplatin resistance in human cancers.

  Cancer research 20100401

• Predonor lymphocyte infusion treatment with 5-azacytidine as salvage treatment in relapsed acute myeloid leukaemia secondary to myelodysplastic syndrome.

  Anti-cancer drugs 20100401

• Impact of genomic methylation on radiation sensitivity of colorectal carcinoma.

  International journal of radiation oncology, biology, physics 20100401

• Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.

  Molecular cancer research : MCR 20100401

• Preface. The biology and treatment of myelodysplastic syndrome.

  Hematology/oncology clinics of North America 20100401

• Epigenetic changes in the myelodysplastic syndrome.

  Hematology/oncology clinics of North America 20100401

• Practical recommendations for hypomethylating agent therapy of patients with myelodysplastic syndromes.

  Hematology/oncology clinics of North America 20100401

• [No correlation between the sensitivity to 5-aza-dC and the global DNA methylation level in hepatocellular carcinoma cells].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20100401

• Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.

  Journal of gastroenterology and hepatology 20100401

• DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta.

  The Journal of biological chemistry 20100326

• Differential epigenetic regulation of BDNF and NT-3 genes by trichostatin A and 5-aza-2'-deoxycytidine in Neuro-2a cells.

  Biochemical and biophysical research communications 20100326

• IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer.

  Oncogene 20100318

• Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer.

  International journal of cancer 20100315

• Azacitidine for the treatment of lower risk myelodysplastic syndromes : a retrospective study of 74 patients enrolled in an Italian named patient program.

  Cancer 20100315

• DNA demethylation in retinal neurocytes contributes to the upregulation of DNA repair protein, Ku80.

  Neuroreport 20100310

• RA induces the neural-like cells generated from epigenetic modified NIH/3T3 cells.

  Molecular biology reports 20100301

• IGFBP7 is a p53-responsive gene specifically silenced in colorectal cancer with CpG island methylator phenotype.

  Carcinogenesis 20100301

• 5-Aza-2'-deoxycytidine sensitizes busulfan-resistant myeloid leukemia cells by regulating expression of genes involved in cell cycle checkpoint and apoptosis.

  Leukemia research 20100301

• Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi.

  Immunology 20100301

• DNA methylation regulates adenosine A(2A) receptor cell surface expression levels.

  Journal of neurochemistry 20100301

• Maintenance therapy in acute myeloid leukemia revisited: will new agents rekindle an old interest?

  Current opinion in hematology 20100301

• Prolonged responses in patients with MDS and CMML treated with azacitidine and etanercept.

  British journal of haematology 20100301

• Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.

  Laboratory investigation; a journal of technical methods and pathology 20100301

• DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target.

  Cancer research 20100301

• Long-term survival and characterisation of human umbilical cord-derived mesenchymal stem cells on dermal equivalents.

  Differentiation; research in biological diversity 20100301

• Novel approaches for myelodysplastic syndromes: beyond hypomethylating agents.

  Current opinion in hematology 20100301

• The effects of DNA methyltransferase inhibitors and histone deacetylase inhibitors on digit regeneration in mice.

  Regenerative medicine 20100301

• Valproic acid in the complex therapy of malignant tumors.

  Current drug targets 20100301

• Antineoplastic effects of decitabine, an inhibitor of DNA promoter methylation, in adrenocortical carcinoma cells.

  Archives of surgery (Chicago, Ill. : 1960) 20100301

• [Effects of 5-Aza-2'-deoxycitydine and trichostatin A on expression and apoptosis of ALDH1a2 gene in human bladder cancer cell lines].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20100301

• JAK2 V617F mutation in myelodysplastic syndrome, myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable, refractory anemia with ring sideroblasts with thrombocytosis, and acute myeloid leukemia.

  The Korean journal of hematology 20100301

• Epigenetic silencing of TNFSF7 (CD70) by DNA methylation during progression to breast cancer.

  Molecules and cells 20100227

• hGH-V gene expression and promoter activity under glucose and 5-azacytidine (5azaC) effects.

  Gene 20100215

• X-linked ectodermal dysplasia receptor is downregulated in breast cancer via promoter methylation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20100215

• Use of Drosophila deoxynucleoside kinase to study mechanism of toxicity and mutagenicity of deoxycytidine analogs in Escherichia coli.

  DNA repair 20100204

• 5-Azacitidine for myelodysplasia before allogeneic hematopoietic cell transplantation.

  Bone marrow transplantation 20100201

• Fabrication of novel hepatoma-targeting microdisks by hydrogen bond-assisted self-assembly of an azacitidine-conjugating amphiphilic random copolymer.

  Acta biomaterialia 20100201

• Outcome prediction and risk assessment by quantitative pyrosequencing methylation analysis of the SFN gene in advanced stage, high-risk, neuroblastic tumor patients.

  International journal of cancer 20100201

• Aberrant DNA methylation of integrin alpha4: a potential novel role for metastasis of cholangiocarcinoma.

  Journal of cancer research and clinical oncology 20100201

• Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor.

  Leukemia research 20100201

• 5-azacitidine prolongs overall survival in patients with myelodysplastic syndrome--a systematic review and meta-analysis.

  Haematologica 20100201

• Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100201

• Inhibition of methylation decreases osteoblast differentiation via a non-DNA-dependent methylation mechanism.

  Bone 20100201

• Decitabine versus 5-azacitidine for the treatment of myelodysplastic syndrome: adjusted indirect meta-analysis.

  Haematologica 20100201

• Cardiomyogenic differentiation of human bone marrow mesenchymal cells: Role of cardiac extract from neonatal rat cardiomyocytes.

  Differentiation; research in biological diversity 20100201

• Resistance to 5-aza-2'-deoxycytidine in genic regions compared to non-genic repetitive sequences.

  The Journal of reproduction and development 20100201

• Multicenter, phase II study of decitabine for the first-line treatment of older patients with acute myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201

• Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201

• Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines.

  Leukemia & lymphoma 20100201

• DNA methylation and its involvement in carboxylesterase 1A1 (CES1A1) gene expression.

  Xenobiotica; the fate of foreign compounds in biological systems 20100201

• Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation.

  The FEBS journal 20100201

• Tissue factor pathway inhibitor 2 (TFPI2) is frequently silenced by aberrant promoter hypermethylation in gastric cancer.

  Cancer genetics and cytogenetics 20100201

• Stem cell therapy: pieces of the puzzle.

  Journal of cardiovascular translational research 20100201

• The role of C1GALT1C1 in lipopolysaccharide-induced IgA1 aberrant O-glycosylation in IgA nephropathy.

  Clinical and investigative medicine. Medecine clinique et experimentale 20100201

• Age-associated epigenetic modifications in human DNA increase its immunogenicity.

  Aging 20100201

• Effective control of sickle cell disease with hydroxyurea therapy.

  Indian journal of pharmacology 20100201

• Will DNA methylation inhibitors work in solid tumors? A review of the clinical experience with azacitidine and decitabine in solid tumors.

  Epigenomics 20100201

• Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.

  Oncogene 20100128

• Immune dysregulation in myelodysplastic syndrome.

  Hematology reports 20100126

• DNA methyltransferase inhibition induces mouse embryonic stem cell differentiation into endothelial cells.

  Experimental cell research 20100115

• Efficient readout of posttranslational codes on the 50-residue tail of histone H3 by high-resolution MS/MS.

  Analytical biochemistry 20100115

• DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection.

  Analytical biochemistry 20100115

• Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene.

  The Journal of biological chemistry 20100115

• Controlling destiny through chemistry: small-molecule regulators of cell fate.

  ACS chemical biology 20100115

• SLIT2 attenuation during lung cancer progression deregulates beta-catenin and E-cadherin and associates with poor prognosis.

  Cancer research 20100115

• Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting.

  Blood 20100107

• Comparison of various criteria in predicting treatment response and prognosis of patients with myelodysplastic syndrome treated with azacitidine.

  Annals of hematology 20100101

• Frequent methylation of RASSF1A in synovial sarcoma and the anti-tumor effects of 5-aza-2'-deoxycytidine against synovial sarcoma cell lines.

  Journal of cancer research and clinical oncology 20100101

• Incorporating novel agents in the treatment of myelodysplastic syndromes.

  Leukemia research 20100101

• Regulation of Toll-like receptor 4-associated MD-2 in intestinal epithelial cells: a comprehensive analysis.

  Innate immunity 20100101

• Stability of transgenes in long-term micropropagation of plants of transgenic birch (Betula platyphylla).

  Biotechnology letters 20100101

• Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer.

  Human pathology 20100101

• Impaired active demethylation of the paternal genome in pronuclear-stage rat zygotes produced by in vitro fertilization or intracytoplasmic sperm injection.

  Molecular reproduction and development 20100101

• Tamoxifen epigenetically modulates CXCL12 expression in MCF-7 breast cancer cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100101

• Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine.

  Leukemia 20100101

• Expression and function of CD9 in melanoma cells.

  Molecular carcinogenesis 20100101

• Gene silencing of MIR22 in acute lymphoblastic leukaemia involves histone modifications independent of promoter DNA methylation.

  British journal of haematology 20100101

• Oncogenic BRAFV600E induces expression of neuronal differentiation marker MAP2 in melanoma cells by promoter demethylation and down-regulation of transcription repressor HES1.

  The Journal of biological chemistry 20100101

• Identification of a functional network of human epigenetic silencing factors.

  The Journal of biological chemistry 20100101

• 5'-AZA induces Ngn3 expression and endocrine differentiation in the PANC-1 human ductal cell line.

  Biochemical and biophysical research communications 20100101

• DNA methylation-dependent suppression of HIF1A in an immature hematopoietic cell line HMC-1.

  Biochemical and biophysical research communications 20100101

• Decitabine in the treatment of myelodysplastic syndromes.

  Expert review of anticancer therapy 20100101

• Report of a phase 1/2 study of a combination of azacitidine and cytarabine in acute myelogenous leukemia and high-risk myelodysplastic syndromes.

  Leukemia & lymphoma 20100101

• [Effect of 5-Aza-CdR on expression and methylation of E-cadherin gene in human colon carcinoma cells].

  Chinese journal of cancer 20100101

• Multifactorial regulation of E-cadherin expression: an integrative study.

  Molecular cancer therapeutics 20100101

• Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells.

  Molecular cancer therapeutics 20100101

• Myelodysplastic syndromes.

  Annual review of medicine 20100101

• Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.

  PloS one 20100101

• Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma.

  Neoplasia (New York, N.Y.) 20100101

• Decitabine.

  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101

• 5-Azacytidine/Azacitidine.

  Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101

• Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.

  BMC molecular biology 20100101

• Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector.

  Virology journal 20100101

• Cooperation of multiple chromatin modifications can generate unanticipated stability of epigenetic States in Arabidopsis.

  The Plant cell 20100101

• The site specific demethylation in the 5'-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription.

  PloS one 20100101

• A comparison of azacitidine and decitabine activities in acute myeloid leukemia cell lines.

  PloS one 20100101

• Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents.

  Journal of hematology & oncology 20100101

• Caspase 8 and maspin are downregulated in breast cancer cells due to CpG site promoter methylation.

  BMC cancer 20100101

• Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.

  BMC medical genomics 20100101

• Osteopontin regulates human glioma cell invasiveness and tumor growth in mice.

  Neuro-oncology 20100101

• A role for age-related changes in TGFbeta signaling in aberrant chondrocyte differentiation and osteoarthritis.

  Arthritis research & therapy 20100101

• Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation.

  PloS one 20100101

• Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks.

  Molecular cancer 20100101

• [Effectiveness and safety of 5-azacitidine in three patients with myelodysplastic syndromes].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

• Genomic variants associated with primary biliary cirrhosis.

  Genome medicine 20100101

• Regulation of gene expression in protozoa parasites.

  Journal of biomedicine & biotechnology 20100101

• Transgenerational adaptation of Arabidopsis to stress requires DNA methylation and the function of Dicer-like proteins.

  PloS one 20100101

• Mechanical strain modulates age-related changes in the proliferation and differentiation of mouse adipose-derived stromal cells.

  BMC cell biology 20100101

• Temozolomide-induced myelodysplasia.

  Advances in hematology 20100101

• BORIS (CTCFL) is not expressed in most human breast cell lines and high grade breast carcinomas.

  PloS one 20100101

• A quantitative proteomic analysis of long-term memory.

  Molecular brain 20100101

• [Elderly patients with myelodysplastic syndrome with del 5q receiving lenalidomide: two case reports with poor prognosis].

  Annales de biologie clinique 20100101

• Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes.

  Clinical advances in hematology & oncology : H&O 20100101

• Circadian rhythm and its role in malignancy.

  Journal of circadian rhythms 20100101

• Red blood cell transfusion independence following the initiation of iron chelation therapy in myelodysplastic syndrome.

  Advances in hematology 20100101

• Effective and steady differentiation of a clonal derivative of P19CL6 embryonal carcinoma cell line into beating cardiomyocytes.

  Journal of biomedicine & biotechnology 20100101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100101

• Combination stem cell therapy for heart failure.

  International archives of medicine 20100101

• Functional neural differentiation of human adipose tissue-derived stem cells using bFGF and forskolin.

  BMC cell biology 20100101

• Cell-based therapy for urinary incontinence.

  Korean journal of urology 20100101

• Oral Ezatiostat HCl (TLK199) and Myelodysplastic syndrome: a case report of sustained hematologic response following an abbreviated exposure.

  Journal of hematology & oncology 20100101

• Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights.

  Journal of hematology & oncology 20100101

• Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells.

  PloS one 20100101

• NGX6 gene mediated by promoter methylation as a potential molecular marker in colorectal cancer.

  BMC cancer 20100101

• High-risk myelodysplastic syndromes: chemotherapy, transplantation, and beyond.

  Current hematologic malignancy reports 20100101

• [Effect of 5-azadeoxycytidine and retinoic acid on expression of genomic imprinting in parthenogenetic mouse embryos].

  Ontogenez 20100101

• Melanoma: Stem cells, sun exposure and hallmarks for carcinogenesis, molecular concepts and future clinical implications.

  Journal of carcinogenesis 20100101

• The apelin-APJ pathway exists in cardiomyogenic cells derived from mesenchymal stem cells in vitro and in vivo.

  Cell transplantation 20100101

• HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.

  PloS one 20100101

• BISMA--fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences.

  BMC bioinformatics 20100101

• Genome-wide changes accompanying the knockdown of Ep-CAM in retinoblastoma.

  Molecular vision 20100101

• Seladin-1 expression is regulated by promoter methylation in adrenal cancer.

  BMC cancer 20100101

• Beta-thalassemia.

  Orphanet journal of rare diseases 20100101

• The aberrant asynchronous replication - characterizing lymphocytes of cancer patients - is erased following stem cell transplantation.

  BMC cancer 20100101

• Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.

  PloS one 20100101

• Vascular endothelial growth factor-related pathways in hemato-lymphoid malignancies.

  Journal of oncology 20100101

• Active chromatin marks are retained on X chromosomes lacking gene or repeat silencing despite XIST/Xist expression in somatic cell hybrids.

  PloS one 20100101

• Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma.

  BMC cancer 20100101

• Impaired cell surface expression of HLA-B antigens on mesenchymal stem cells and muscle cell progenitors.

  PloS one 20100101

• Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies.

  Journal of translational medicine 20100101

• Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.

  BMC cancer 20100101

• An in vitro system for studying murid herpesvirus-4 latency and reactivation.

  PloS one 20100101

• Active loss of DNA methylation in two-cell stage goat embryos.

  The International journal of developmental biology 20100101

• Multiple mesodermal lineage differentiation of Apodemus sylvaticus embryonic stem cells in vitro.

  BMC cell biology 20100101

• Expression of RAN, ZHX-2, and CHC1L genes in multiple myeloma patients and in myeloma cell lines treated with HDAC and Dnmts inhibitors.

  Neoplasma 20100101

• Clinical trials with anti-angiogenic agents in hematological malignancies.

  Journal of angiogenesis research 20100101

• The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition.

  Molecular cancer 20100101

• Hypomethylation of IL10 and IL13 promoters in CD4+ T cells of patients with systemic lupus erythematosus.

  Journal of biomedicine & biotechnology 20100101

• Azacytidine induces cell cycle arrest and suppression of neuroendocrine markers in carcinoids.

  International journal of clinical and experimental medicine 20100101

• Altered intra-nuclear organisation of heterochromatin and genes in ICF syndrome.

  PloS one 20100101

• An update on the safety and efficacy of decitabine in the treatment of myelodysplastic syndromes.

  OncoTargets and therapy 20100101

• Demethylation by 5-aza-2'-deoxycytidine in colorectal cancer cells targets genomic DNA whilst promoter CpG island methylation persists.

  BMC cancer 20100101

• Cytokine-induced monocyte characteristics in SLE.

  Journal of biomedicine & biotechnology 20100101

• Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines.

  PloS one 20100101

• Exon 2 methylation inhibits hepaCAM expression in transitional cell carcinoma of the bladder.

  Urologia internationalis 20100101

• Challenges in treating older patients with acute myeloid leukemia.

  Journal of oncology 20100101

• BORIS/CTCFL expression is insufficient for cancer-germline antigen gene expression and DNA hypomethylation in ovarian cell lines.

  Cancer immunity 20100101

• Soy phytoestrogens modify DNA methylation of GSTP1, RASSF1A, EPH2 and BRCA1 promoter in prostate cancer cells.

  In vivo (Athens, Greece) 20100101

• Overexpression of hTERT increases stem-like properties and decreases spontaneous differentiation in human mesenchymal stem cell lines.

  Journal of biomedical science 20100101

• Personalized therapies in the cancer 'omics' era.

  Molecular cancer 20100101

• Oxidative stress and DNA methylation in prostate cancer.

  Obstetrics and gynecology international 20100101

• Remodeling genomes with artificial transcription factors (ATFs).

  Methods in molecular biology (Clifton, N.J.) 20100101

• Trichostatin A and 5-azacytidine both cause an increase in global histone H4 acetylation and a decrease in global DNA and H3K9 methylation during mitosis in maize.

  BMC plant biology 20100101

• Transpositional reactivation of the Dart transposon family in rice lines derived from introgressive hybridization with Zizania latifolia.

  BMC plant biology 20100101

• Recent advances in the treatment of acute myeloid leukemia.

  F1000 medicine reports 20100101

• Molecular and therapeutic potential and toxicity of valproic acid.

  Journal of biomedicine & biotechnology 20100101

• L1CAM expression in endometrial carcinomas is regulated by usage of two different promoter regions.

  BMC molecular biology 20100101

• DNA methylation patterns provide insight into epigenetic regulation in the Pacific oyster (Crassostrea gigas).

  BMC genomics 20100101

• MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide.

  Molecular vision 20100101

• Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine.

  PloS one 20100101

• Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics.

  Genome medicine 20100101

• Ferroportin and erythroid cells: an update.

  Advances in hematology 20100101

• Epigenetic approaches in the treatment of myelodysplastic syndromes: clinical utility of azacitidine.

  OncoTargets and therapy 20100101

• Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection.

  BMC genomics 20100101

• A phase I biological study of azacitidine (Vidaza™) to determine the optimal dose to inhibit DNA methylation.

  Epigenetics 20100101

• Epigenetic modifiers are necessary but not sufficient for reprogramming non-myelinating cells into myelin gene-expressing cells.

  PloS one 20100101

• DNA methylation and cancer.

  Advances in genetics 20100101

• Equitoxic doses of 5-azacytidine and 5-aza-2'deoxycytidine induce diverse immediate and overlapping heritable changes in the transcriptome.

  PloS one 20100101

• Chromatin-modifying agents increase transcription of CYP46A1, a key player in brain cholesterol elimination.

  Journal of Alzheimer's disease : JAD 20100101

• S110, a novel decitabine dinucleotide, increases fetal hemoglobin levels in baboons (P. anubis).

  Journal of translational medicine 20100101

• Cell line-dependent variability in HIV activation employing DNMT inhibitors.

  Virology journal 20100101

• Recent advances in diagnosis and treatment of chronic myeloproliferative neoplasms.

  F1000 medicine reports 20100101

• Safety and efficacy of azacitidine in myelodysplastic syndromes.

  Drug design, development and therapy 20100101

• The effect of differentiating and apoptotic agents on notch signalling pathway in hepatoblastoma.

  Hepato-gastroenterology 20100101

• TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma.

  BMC cancer 20100101

• PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis.

  PloS one 20100101

• Down-regulation of serum/glucocorticoid regulated kinase 1 in colorectal tumours is largely independent of promoter hypermethylation.

  PloS one 20100101

• Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line.

  Journal of experimental & clinical cancer research : CR 20100101

• Epigenetic control of the basal-like gene expression profile via Interleukin-6 in breast cancer cells.

  Molecular cancer 20100101

• Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells from hematopoietic stem cells.

  Journal of immune based therapies and vaccines 20100101

• Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation.

  Molecular cancer 20100101

• Reactivating aberrantly hypermethylated p15 gene in leukemic T cells by a phenylhexyl isothiocyanate mediated inter-active mechanism on DNA and chromatin.

  Journal of hematology & oncology 20100101

• Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells.

  Reproductive biology and endocrinology : RB&E 20100101

• Gemcitabine functions epigenetically by inhibiting repair mediated DNA demethylation.

  PloS one 20100101

• Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.

  BMC cancer 20100101

• Characterization of a 5-azacytidine-induced developmental Aspergillus fumigatus variant.

  Virulence 20100101

• Epigenomics in cancer management.

  Cancer management and research 20100101

• Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.

  Nutrition journal 20100101

• Early Detection of t(8;21) Chromosomal Translocations During Treatment of PML-RARA Positive Acute Promyelocytic Leukemia: A Case Study.

  Clinical Medicine Insights. Oncology 20100101

• How much? How frequent? How long? A clinical guide to new therapies in myelodysplastic syndromes.

  Hematology. American Society of Hematology. Education Program 20100101

• Creating transplant tolerance by taming adverse intragraft innate immunity.

  F1000 biology reports 20100101

• Dose-modified lenalidomide induces sustained hematological response in patients with intermediate to high risk myelodysplasia.

  Mediterranean journal of hematology and infectious diseases 20100101

• Role and timing of hematopoietic cell transplantation for myelodysplastic syndrome.

  Mediterranean journal of hematology and infectious diseases 20100101

• New treatments for myelodysplastic syndromes.

  Mediterranean journal of hematology and infectious diseases 20100101

• Epigenetic regulation of wnt pathway antagonists in human glioblastoma multiforme.

  Genes & cancer 20100101

• Rationale for Targeting CD6 as a Treatment for Autoimmune Diseases.

  Arthritis 20100101

• Stem cells: An overview with respect to cardiovascular and renal disease.

  Journal of natural science, biology, and medicine 20100101

• Myelodysplastic syndromes/neoplasms: recent classification system based on World Health Organization Classification of Tumors - International Agency for Research on Cancer for Hematopoietic and Lymphoid Tissues.

  Journal of blood medicine 20100101

• Molecular basis of Mammalian embryonic stem cell pluripotency and self-renewal.

  Acta naturae 20100101

• Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells.

  The Journal of biological chemistry 20091225

• Impact of DNA demethylation of the G0S2 gene on the transcription of G0S2 in squamous lung cancer cell lines with or without nuclear receptor agonists.

  Biochemical and biophysical research communications 20091225

• 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.

  Toxicology letters 20091215

• Superior outcome with hypomethylating therapy in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome and chromosome 5 and 7 abnormalities.

  Cancer 20091215

• High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors.

  Cancer research 20091215

• Characterization of azacytidine/poly(L-lactic) acid particles prepared by supercritical antisolvent precipitation.

  Journal of pharmaceutical and biomedical analysis 20091205

• Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation.

  Biochemical and biophysical research communications 20091204

• Undifferentiated hematopoietic cells are characterized by a genome-wide undermethylation dip around the transcription start site and a hierarchical epigenetic plasticity.

  Blood 20091203

• Regulated expression of CCL21 in the prostate tumor microenvironment inhibits tumor growth and metastasis in an orthotopic model of prostate cancer.

  Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20091201

• Epigenetic modifications: new therapeutic targets in primary myelofibrosis.

  Current stem cell research & therapy 20091201

• Epigenetic regulation of microRNA expression in colorectal cancer.

  International journal of cancer 20091201

• DNA methylation regulates constitutive expression of Stat6 regulatory genes SOCS-1 and SHP-1 in colon cancer cells.

  Journal of cancer research and clinical oncology 20091201

• Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells.

  Toxicology and applied pharmacology 20091201

• Isolation of cancer-specific chimeric transcripts induced by hypomethylation of the LINE-1 antisense promoter.

  Genomics 20091201

• Preventing autoimmunity by regulating regulatory T-cell induction.

  Journal of molecular medicine (Berlin, Germany) 20091201

• Effect of 5-azacytidine induction duration on differentiation of human first-trimester fetal mesenchymal stem cells towards cardiomyocyte-like cells.

  Interactive cardiovascular and thoracic surgery 20091201

• Induction of Foxp3 demethylation increases regulatory CD4+CD25+ T cells and prevents the occurrence of diabetes in mice.

  Journal of molecular medicine (Berlin, Germany) 20091201

• Defective interleukin-4/Stat6 activity correlates with increased constitutive expression of negative regulators SOCS-3, SOCS-7, and CISH in colon cancer cells.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20091201

• Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.

  Molecular cancer therapeutics 20091201

• Novel oligoamine analogues inhibit lysine-specific demethylase 1 and induce reexpression of epigenetically silenced genes.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20091201

• DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

  Arthritis and rheumatism 20091201

• Mechanism of DNA replication-dependent transcriptional activation of the acetylcholinesterase gene in the Ciona intestinalis embryo.

  Development, growth & differentiation 20091201

• A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide.

  Cancer prevention research (Philadelphia, Pa.) 20091201

• Decitabine treatment of patients with higher-risk myelodysplastic syndromes.

  Leukemia research 20091201

• Hypomethylating agents in myelodysplastic syndromes changing the inevitable: the value of azacitidine as maintenance therapy, effects on transfusion and combination with other agents.

  Leukemia research 20091201

• In vitro basis for treatment with hypomethylating agents and histone deacetylase inhibitors: can epigenetic changes be used to monitor treatment?

  Leukemia research 20091201

• Azacitidine in lower-risk myelodysplastic syndromes.

  Leukemia research 20091201

• Review of azacitidine trials in Intermediate-2-and High-risk myelodysplastic syndromes.

  Leukemia research 20091201

• Epigenetic silencing of CRABP2 and MX1 in head and neck tumors.

  Neoplasia (New York, N.Y.) 20091201

• Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance.

  Neoplasia (New York, N.Y.) 20091201

• Skeletal muscle-derived stem cells exhibit cardiocyte competences.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20091201

• The human retinoblastoma gene is imprinted.

  PLoS genetics 20091201

• Methods in DNA methylation profiling.

  Epigenomics 20091201

• LARG at chromosome 11q23 has functional characteristics of a tumor suppressor in human breast and colorectal cancer.

  Oncogene 20091126

• Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells.

  Lung cancer (Amsterdam, Netherlands) 20091101

• Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine.

  Annals of hematology 20091101

• Non-intensive treatment with low-dose 5-aza-2'-deoxycytidine (DAC) prior to allogeneic blood SCT of older MDS/AML patients.

  Bone marrow transplantation 20091101

• Three epigenetic drugs up-regulate homeobox gene Rhox5 in cancer cells through overlapping and distinct molecular mechanisms.

  Molecular pharmacology 20091101

• 5-Azacytidine can induce lethal mutagenesis in human immunodeficiency virus type 1.

  Journal of virology 20091101

• Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts.

  Cell biology international 20091101

• Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells.

  Oncology reports 20091101

• Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer.

  International journal of oncology 20091101

• Regulation of EP receptors in non-small cell lung cancer by epigenetic modifications.

  European journal of cancer (Oxford, England : 1990) 20091101

• DNA demethylation at specific CpG sites in the IL1B promoter in response to inflammatory cytokines in human articular chondrocytes.

  Arthritis and rheumatism 20091101

• Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes.

  PLoS pathogens 20091101

• Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.

  PLoS genetics 20091101

• Tumor cell growth inhibition and cell differentiation analysis in a canine mammary tumor cell line (MCM-B2) treated with four chemical reagents.

  The Journal of veterinary medical science 20091101

• Myelodysplastic syndromes: emerging therapies, survival, and alternative outcomes.

  Managed care (Langhorne, Pa.) 20091101

• Alternative dosing schedules for methylation inhibitors in MDS treatment.

  Managed care (Langhorne, Pa.) 20091101

• Myelodysplastic syndromes: health care management considerations.

  Managed care (Langhorne, Pa.) 20091101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20091101

• Repression of induced apoptosis in the 2-cell bovine embryo involves DNA methylation and histone deacetylation.

  Biochemical and biophysical research communications 20091016

• Suberoylanilide hydroxamic acid promotes cardiomyocyte differentiation of rat mesenchymal stem cells.

  Experimental cell research 20091015

• MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation.

  Blood 20091015

• Azacytidine inhibits RNA methylation at DNMT2 target sites in human cancer cell lines.

  Cancer research 20091015

• Alteration of transcriptional profile in human bronchial epithelial cells induced by cigarette smoke condensate.

  Toxicology letters 20091008

• Epigenetic therapies move into new territory, but how exactly do they work?

  Journal of the National Cancer Institute 20091007

• Homologous recombination but not nucleotide excision repair plays a pivotal role in tolerance of DNA-protein cross-links in mammalian cells.

  The Journal of biological chemistry 20091002

• DNA methylation and methyl-CpG binding proteins: developmental requirements and function.

  Chromosoma 20091001

• Direct effect of cocaine on epigenetic regulation of PKCepsilon gene repression in the fetal rat heart.

  Journal of molecular and cellular cardiology 20091001

• IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling.

  Cell death and differentiation 20091001

• Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms.

  Experimental hematology 20091001

• Inactive X chromosome-specific reduction in placental DNA methylation.

  Human molecular genetics 20091001

• Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell lines.

  The Journal of pharmacology and experimental therapeutics 20091001

• Relationship between methylation status of ERCC1 promoter and radiosensitivity in glioma cell lines.

  Cell biology international 20091001

• Methylation-associated silencing of S100A4 expression in human epidermal cancers.

  Experimental dermatology 20091001

• Atypical presentations of Sweet's syndrome in patients with MDS/AML receiving combinations of hypomethylating agents with histone deacetylase inhibitors.

  American journal of hematology 20091001

• Correction of the abnormal trafficking of primary myelofibrosis CD34+ cells by treatment with chromatin-modifying agents.

  Cancer research 20091001

• Development of a novel output value for quantitative assessment in methylated DNA immunoprecipitation-CpG island microarray analysis.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20091001

• Fluorescence polarization combined capillary electrophoresis immunoassay for the sensitive detection of genomic DNA methylation.

  Analytical chemistry 20091001

• A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20091001

• Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats.

  Arthritis and rheumatism 20091001

• Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax.

  Neoplasia (New York, N.Y.) 20091001

• [Management of anemia and bone marrow hypoplasia in the treatment of myeloid leukemia].

  Nihon rinsho. Japanese journal of clinical medicine 20091001

• [Novel therapeutic agents for myelodysplastic syndrome].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001

• Enhancing survival outcomes in the management of patients with higher-risk myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20091001

• Reduction of phosphoinositide-phospholipase C beta1 methylation predicts the responsiveness to azacitidine in high-risk MDS.

  Proceedings of the National Academy of Sciences of the United States of America 20090929

• Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.

  Blood 20090924

• DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.

  Biochemical pharmacology 20090915

• Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090915

• Case records of the Massachusetts General Hospital. Case 28-2009. A 68-year-old man with fatigue, cough, and peripheral-blood monocytosis.

  The New England journal of medicine 20090910

• Decitabine-induced effusions.

  Leukemia research 20090901

• Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia.

  Leukemia 20090901

• Blockade of MEK signaling potentiates 5-Aza-2'-deoxycytidine-induced apoptosis and upregulation of p21(waf1) in acute myelogenous leukemia cells.

  International journal of cancer 20090901

• c-Myc regulates the coordinated transcription of brain disease-related PDCD10-SERPINI1 bidirectional gene pair.

  Molecular and cellular neurosciences 20090901

• Expression level and DNA methylation status of glutathione-S-transferase genes in normal murine prostate and TRAMP tumors.

  The Prostate 20090901

• Functional neurons and melanocytes induced from immortal lines of postnatal neural crest-like stem cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901

• Human cardiac mesoangioblasts isolated from hypertrophic cardiomyopathies are greatly reduced in proliferation and differentiation potency.

  Cardiovascular research 20090901

• Cord blood stem cell expansion is permissive to epigenetic regulation and environmental cues.

  Experimental hematology 20090901

• Chemical induction of silent biosynthetic pathway transcription in Aspergillus niger.

  Journal of industrial microbiology & biotechnology 20090901

• Simultaneous PKC and cAMP activation induces differentiation of human dental pulp stem cells into functionally active neurons.

  Neurochemistry international 20090901

• A phase II study of 5-day intravenous azacitidine in patients with myelodysplastic syndromes.

  American journal of hematology 20090901

• Decitabine combined with fractionated gemtuzumab ozogamicin therapy in patients with relapsed or refractory acute myeloid leukemia.

  American journal of hematology 20090901

• Neutrophilic panniculitis associated with myelodysplastic syndrome with abnormal nuclear forms.

  Journal of cutaneous pathology 20090901

• Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090901

• Hematology: Azacitidine improves survival in myelodysplastic syndromes.

  Nature reviews. Clinical oncology 20090901

• A 64-year-old male with fever and persistent lung infiltrate.

  Respiratory care 20090901

• [Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2].

  Ai zheng = Aizheng = Chinese journal of cancer 20090901

• [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on P16, hMLH1 and MGMT genes and DNA methylation in human gastric cancer cells].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090901

• [Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090901

• [Up-regulation of major histocompatibility complex class I-related molecules A (MICA) induced by 5-aza-2'-deoxycytidine].

  Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090901

• In vitro myogenic differentiation of human bone marrow-derived mesenchymal stem cells as a potential treatment for urethral sphincter muscle repair.

  Annals of the New York Academy of Sciences 20090901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090901

• [Traditional medicine CDP and promoter demethylation in breast cancer cell lines].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090901

• Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling.

  Journal of cellular and molecular medicine 20090901

• Distribution and sequence of pyknotic cells in rat fetuses exposed to busulfan.

  Journal of toxicologic pathology 20090901

• Epigenetic cross-talk between DNA methylation and histone modifications in human cancers.

  Yonsei medical journal 20090831

• Loss of human ribosomal gene CpG methylation enhances cryptic RNA polymerase II transcription and disrupts ribosomal RNA processing.

  Molecular cell 20090828

• Dynamic changes in DNA methylation during multistep rat lung carcinogenesis induced by 3-methylcholanthrene and diethylnitrosamine.

  Toxicology letters 20090825

• Effect of human umbilical cord blood cells on Ang-II-induced hypertrophy in mice.

  Biochemical and biophysical research communications 20090821

• Quantification of regional DNA methylation by liquid chromatography/tandem mass spectrometry.

  Analytical biochemistry 20090815

• The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation.

  Journal of immunology (Baltimore, Md. : 1950) 20090815

• Re-differentiation of thyroid carcinoma cell lines treated with 5-Aza-2'-deoxycytidine and retinoic acid.

  Molecular and cellular endocrinology 20090813

• Multicenter study of decitabine administered daily for 5 days every 4 weeks to adults with myelodysplastic syndromes: the alternative dosing for outpatient treatment (ADOPT) trial.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810

• Frequent loss of cystatin E/M expression implicated in the progression of prostate cancer.

  Oncogene 20090806

• Promoter CpG methylation of oestrogen receptors in leukaemia.

  Bioscience reports 20090801

• 5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801

• The property of methylated APC gene promotor and its influence on lung cancer cell line.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801

• DNA hypomethylation as Achilles' heel of tumorigenesis: a working hypothesis.

  Cell biology international 20090801

• Cardiac potential of stem cells from whole human umbilical cord tissue.

  Journal of cellular biochemistry 20090801

• Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090801

• iTRAQ-coupled 2-D LC-MS/MS analysis of protein profile associated with HBV-modulated DNA methylation.

  Proteomics 20090801

• RUNX3 gene methylation in epithelial ovarian cancer tissues and ovarian cancer cell lines.

  Omics : a journal of integrative biology 20090801

• Methylation mediated silencing of TMS1 in breast cancer and its potential contribution to docetaxel cytotoxicity.

  Anticancer research 20090801

• Effects of 5-Aza-CdR on the proliferation of human breast cancer cell line MCF-7 and on the expression of Apaf-1 gene.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20090801

• [Effect of demethylating treatment on cytotoxicity of NK-92MI cells].

  Zhongguo shi yan xue ye xue za zhi 20090801

• Evolving strategies in the treatment of MDS and AML.

  Clinical advances in hematology & oncology : H&O 20090801

• Potential of DNMT and its Epigenetic Regulation for Lung Cancer Therapy.

  Current genomics 20090801

• Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells.

  Oncogene 20090730

• Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2.

  The Journal of biological chemistry 20090717

• Lysyl oxidase-like 2 promotes migration in noninvasive breast cancer cells but not in normal breast epithelial cells.

  International journal of cancer 20090715

• Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells.

  Cancer research 20090715

• 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090715

• Treatment with demethylating agent, 5-aza-2'-deoxycytidine enhances therapeutic HPV DNA vaccine potency.

  Vaccine 20090709

• Human neonatal thymus-derived mesenchymal stromal cells: characterization, differentiation, and immunomodulatory properties.

  Tissue engineering. Part A 20090701

• Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine.

  Leukemia research 20090701

• Aberrant expression of TSC2 gene in the newly diagnosed acute leukemia.

  Leukemia research 20090701

• Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia.

  Leukemia 20090701

• Epigenetic down-regulation of BIM expression is associated with reduced optimal responses to imatinib treatment in chronic myeloid leukaemia.

  European journal of cancer (Oxford, England : 1990) 20090701

• Automated quantification of DNA demethylation effects in cells via 3D mapping of nuclear signatures and population homogeneity assessment.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20090701

• Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas.

  Laboratory investigation; a journal of technical methods and pathology 20090701

• Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.

  Molecular cancer therapeutics 20090701

• Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090701

• Azacitidine for the treatment of myelodysplastic syndrome.

  Expert review of anticancer therapy 20090701

• Specific loss of histone H3 lysine 9 trimethylation and HP1gamma/cohesin binding at D4Z4 repeats is associated with facioscapulohumeral dystrophy (FSHD).

  PLoS genetics 20090701

• Global analysis of DNA methylation and transcription of human repetitive sequences.

  Epigenetics 20090701

• S-Adenosylhomocysteine increases beta-amyloid formation in BV-2 microglial cells by increased expressions of beta-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters.

  Neurotoxicology 20090701

• Clinical roundtable monograph. Overall survival and maintenance of MDS patients.

  Clinical advances in hematology & oncology : H&O 20090701

• Clinical roundtable monograph. Choosing an appropriate therapy for lower-risk MDS in the community setting.

  Clinical advances in hematology & oncology : H&O 20090701

• Clinical roundtable monograph. Combination therapies for MDS.

  Clinical advances in hematology & oncology : H&O 20090701

• [Effects of 5-aza-2'-deoxycytidine on the amount of exosomes and secreted immuno-associated proteins by hepatoma cells].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090701

• [E-cadherin promoter methylation and demethylation in epithelial ovarian carcinoma cells].

  Zhonghua fu chan ke za zhi 20090701

• Promoter methylation in the genesis of gastrointestinal cancer.

  Yonsei medical journal 20090630

• Epigenetic regulation of cytokine gene expression in T lymphocytes.

  Yonsei medical journal 20090630

• How I treat patients with myelodysplastic syndromes.

  Blood 20090618

• Epigenetic modifiers: basic understanding and clinical development.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090615

• Targeting DNA methylation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090615

• Synergy of 5-aza-2'-deoxycytidine (DAC) and paclitaxel in both androgen-dependent and -independent prostate cancer cell lines.

  Cancer letters 20090608

• Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia.

  Evidence-based complementary and alternative medicine : eCAM 20090601

• Epigenetic control of differential expression of specific ERG isoforms in acute T-lymphoblastic leukemia.

  Leukemia research 20090601

• Feasibility of allo-SCT after hypomethylating therapy with decitabine for myelodysplastic syndrome.

  Bone marrow transplantation 20090601

• Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models.

  Endocrine-related cancer 20090601

• The DNA methyltransferase inhibitors azacitidine, decitabine and zebularine exert differential effects on cancer gene expression in acute myeloid leukemia cells.

  Leukemia 20090601

• Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.

  International journal of colorectal disease 20090601

• Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21.

  Carcinogenesis 20090601

• Demethylating treatment suppresses natural killer cell cytolytic activity.

  Molecular immunology 20090601

• CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.

  International journal of oncology 20090601

• Therapy related CMML: a case report and review of the literature.

  International journal of hematology 20090601

• The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells.

  The American journal of pathology 20090601

• Interaction of TFAP2C with the estrogen receptor-alpha promoter is controlled by chromatin structure.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090601

• Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090601

• Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1.

  Journal of neurochemistry 20090601

• Chemical decomposition of 5-aza-2'-deoxycytidine (Decitabine): kinetic analyses and identification of products by NMR, HPLC, and mass spectrometry.

  Chemical research in toxicology 20090601

• Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine.

  Biological & pharmaceutical bulletin 20090601

• Disseminated varicella-zoster virus infection following azacitidine in a patient with myelodysplastic syndrome.

  Clinical journal of oncology nursing 20090601

• DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.

  Molecular cancer therapeutics 20090601

• Epigenetic modifiers exacerbate oxidative stress in renal proximal tubule cells.

  Anticancer research 20090601

• Distinct roles for histone methyltransferases G9a and GLP in cancer germ-line antigen gene regulation in human cancer cells and murine embryonic stem cells.

  Molecular cancer research : MCR 20090601

• Use of epigenetic modification to induce FOXP3 expression in naïve T cells.

  Transplantation proceedings 20090601

• Preliminary study on 5-azacytidine anti-myeloma activity in vitro.

  Zhongguo shi yan xue ye xue za zhi 20090601

• [Effect of demethylation treatment on the expression of inhibitory receptor KIR gene in NK-92MI cell line].

  Zhongguo shi yan xue ye xue za zhi 20090601

• Epigenetic regulation of HIV-1 latency by cytosine methylation.

  PLoS pathogens 20090601

• Epstein-barr virus latency in B cells leads to epigenetic repression and CpG methylation of the tumour suppressor gene Bim.

  PLoS pathogens 20090601

• [Detection of O6-methylguanine-DNA methyltransferase promoter methylation in chemotherapy for glioma].

  Ai zheng = Aizheng = Chinese journal of cancer 20090601

• Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.

  Biochemistry. Biokhimiia 20090601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090601

• Clinical implications of gene expression profiling in myelodysplastic syndromes: recognition of ribosomal and translational gene dysregulation and development of predictive assays.

  Best practice & research. Clinical haematology 20090601

• Treatment of chronic lymphocytic leukemia with a hypomethylating agent induces expression of NXF2, an immunogenic cancer testis antigen.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090515

• A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.

  Cancer research 20090515

• DNA methylation inhibits p53-mediated survivin repression.

  Oncogene 20090514

• Differential expression of stromal cell-derived factor 1 in human brain microvascular endothelial cells and pericytes involves histone modifications.

  Biochemical and biophysical research communications 20090508

• Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines.

  European journal of nuclear medicine and molecular imaging 20090501

• The developmental potential of mouse somatic cell nuclear-transferred oocytes treated with trichostatin A and 5-aza-2'-deoxycytidine.

  Zygote (Cambridge, England) 20090501

• DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin.

  Mutagenesis 20090501

• Modulation of DNA methylation by a sesquiterpene lactone parthenolide.

  The Journal of pharmacology and experimental therapeutics 20090501

• 5-AZA-2'-deoxycytidine (5-AZA-CdR) leads to down-regulation of Dnmt1o and gene expression in preimplantation mouse embryos.

  Zygote (Cambridge, England) 20090501

• Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia.

  Cancer 20090501

• The comet assay: a sensitive method for detecting DNA damage in individual cells.

  Methods (San Diego, Calif.) 20090501

• Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.

  Cancer biology & therapy 20090501

• Epigenetic reversal of acquired resistance to 5-fluorouracil treatment.

  Molecular cancer therapeutics 20090501

• Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes.

  Haematologica 20090501

• Epigenetic hierarchy governing Nestin expression.

  Stem cells (Dayton, Ohio) 20090501

• Additive effects of 5-aza-2'-deoxycytidine and irradiation on clonogenic survival of human medulloblastoma cell lines.

  Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20090501

• T-lymphocyte maturation-associated protein gene as a candidate metastasis suppressor for head and neck squamous cell carcinomas.

  Cancer science 20090501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090501

• Enhanced cardiomyogenic differentiation of P19 embryonal carcinoma stem cells.

  Korean circulation journal 20090501

• Myc sensitizes p53-deficient cancer cells to the DNA-damaging effects of the DNA methyltransferase inhibitor decitabine.

  Blood 20090430

• [The empirical study in transplantation of bone marrow mesenchymal stem cells for acute myocardial infarction].

  Zhonghua yi xue za zhi 20090421

• Cardiomyogenic differentiation potential of human adipose precursor cells.

  International journal of cardiology 20090417

• Hematologic response to three alternative dosing schedules of azacitidine in patients with myelodysplastic syndromes.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090410

• Epigenetic silencing of EphA1 expression in colorectal cancer is correlated with poor survival.

  British journal of cancer 20090407

• Treatment of ovarian cancer cell lines with 5-aza-2'-deoxycytidine upregulates the expression of cancer-testis antigens and class I major histocompatibility complex-encoded molecules.

  Cancer immunology, immunotherapy : CII 20090401

• Demethylating agent 5-aza-2'-deoxycytidine activates HLA-G expression in human leukemia cell lines.

  Leukemia research 20090401

• Methylation of the OP-1 promoter: potential role in the age-related decline in OP-1 expression in cartilage.

  Osteoarthritis and cartilage 20090401

• Decitabine is an effective treatment of idiopathic myelofibrosis.

  British journal of haematology 20090401

• Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.

  Acta neuropathologica 20090401

• BTG3 tumor suppressor gene promoter demethylation, histone modification and cell cycle arrest by genistein in renal cancer.

  Carcinogenesis 20090401

• Retroviral delivery of promoter-targeted shRNA induces long-term silencing of HIV-1 transcription.

  Microbes and infection 20090401

• The evolution of hematopoietic SCT in myelodysplastic syndrome.

  Bone marrow transplantation 20090401

• Synergistic effect of trichostatin A and 5-aza-2'-deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study.

  Proteomics 20090401

• Growth inhibition of human cancer cells by 5-aza-2'-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status.

  Molecular cancer therapeutics 20090401

• Durable clinical and cytogenetic remission in an elderly patient with relapsed acute myeloid leukemia treated with low-dose lenalidomide.

  Leukemia & lymphoma 20090401

• [Effect of a methylation inhibitor 5-aza-2'-deoxycytidine on SHP-1 gene expression, proliferation and apoptosis in K562 cells].

  Zhongguo shi yan xue ye xue za zhi 20090401

• LINE-1 methylation in plasma DNA as a biomarker of activity of DNA methylation inhibitors in patients with solid tumors.

  Epigenetics 20090401

• Glucocorticoid receptor alpha and beta variant expression is associated with ASF/SF2 splicing factor upregulation in HT-29 colon cancer and MCF-7 breast carcinoma cells.

  Archives of medical research 20090401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090401

• [5-azacytidine treatment induces tumor suppressor gene XAF1 expression and inhibits proliferation in myeloma cells].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20090401

• Azacitidine: activity and efficacy as an epigenetic treatment of myelodysplastic syndromes.

  Expert review of hematology 20090401

• Hypomethylating drugs convert HA-1-negative solid tumors into targets for stem cell-based immunotherapy.

  Blood 20090319

• Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7.

  Blood 20090319

• Timing is everything: order of administration of 5-aza 2' deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity.

  Cancer letters 20090318

• 6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.

  Biochemistry 20090317

• Epigenetic regulation of c-ROS receptor tyrosine kinase expression in malignant gliomas.

  Cancer research 20090315

• Combined inhibition of DNA methylation and histone acetylation enhances gene re-expression and drug sensitivity in vivo.

  British journal of cancer 20090310

• Diet-induced up-regulation of gene expression in adipocytes without changes in DNA methylation.

  The Kobe journal of medical sciences 20090310

• A limited number of 5-azacitidine cycles can be effective treatment in MDS.

  Annals of hematology 20090301

• Complete cytogenetic remission after decitabine treatment in a patient with secondary AML harbouring high p15INK4b gene methylation and high global DNA methylation.

  Annals of hematology 20090301

• A paramutation phenomenon is involved in the genetics of maize low phytic acid1-241 (lpa1-241) trait.

  Heredity 20090301

• Epigenetic regulation of E-cadherin controls endometrial receptivity.

  Endocrinology 20090301

• Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.

  Journal of neuro-oncology 20090301

• Promoter methylation blocks FES protein-tyrosine kinase gene expression in colorectal cancer.

  Genes, chromosomes & cancer 20090301

• Combination of DNA methylation inhibitor 5-azacytidine and arsenic trioxide has synergistic activity in myeloma.

  European journal of haematology 20090301

• Regulation of surfactant protein B gene expression in bone marrow-derived cells.

  Stem cells (Dayton, Ohio) 20090301

• Interaction between the mismatch repair and nucleotide excision repair pathways in the prevention of 5-azacytidine-induced CG-to-GC mutations in Escherichia coli.

  DNA repair 20090301

• Characterization of autonomous Dart1 transposons belonging to the hAT superfamily in rice.

  Molecular genetics and genomics : MGG 20090301

• Differential CpG island methylation of murine adenine nucleotide translocase genes.

  Biochimica et biophysica acta 20090301

• A systematic assessment of radiation dose enhancement by 5-Aza-2'-deoxycytidine and histone deacetylase inhibitors in head-and-neck squamous cell carcinoma.

  International journal of radiation oncology, biology, physics 20090301

• Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090301

• Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study.

  The Lancet. Oncology 20090301

• Improving survival in myelodysplastic syndromes.

  The Lancet. Oncology 20090301

• DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.

  PLoS genetics 20090301

• GSTP1 determines cis-platinum cytotoxicity in gastric adenocarcinoma MGC803 cells: regulation by promoter methylation and extracellular regulated kinase signaling.

  Anti-cancer drugs 20090301

• Optimal sequencing of treatments for patients with myelodysplastic syndromes.

  Current opinion in hematology 20090301

• Novel strategies for patients with chronic myeloproliferative disorders.

  Current opinion in hematology 20090301

• Is stem cell-based therapy going on or out for cardiac disease?

  Korean circulation journal 20090301

• Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.

  Life sciences 20090227

• The context and potential of epigenetics in oncology.

  British journal of cancer 20090224

• Silencing of the CKII alpha and CKII alpha' genes during cellular senescence is mediated by DNA methylation.

  Gene 20090215

• The presence of a methylation fingerprint of Helicobacter pylori infection in human gastric mucosae.

  International journal of cancer 20090215

• Methylation-mediated repression of GADD45alpha in prostate cancer and its role as a potential therapeutic target.

  Cancer research 20090215

• Epigenetic therapy upregulates the tumor suppressor microRNA-126 and its host gene EGFL7 in human cancer cells.

  Biochemical and biophysical research communications 20090213

• Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation.

  Blood 20090212

• Inhibition of cytidine deaminase by zebularine enhances the antineoplastic action of 5-aza-2'-deoxycytidine.

  Cancer chemotherapy and pharmacology 20090201

• Progressive silencing of p14ARF in oesophageal adenocarcinoma.

  Journal of cellular and molecular medicine 20090201

• Effect of 5-azacytidine on the methylation aspects of NMDA receptor NR2B gene in the cultured cortical neurons of mice.

  Neurochemical research 20090201

• Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine.

  The Plant journal : for cell and molecular biology 20090201

• DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors.

  Clinical immunology (Orlando, Fla.) 20090201

• Transcriptional activity of the novel identified human yy2 promoter is modified by DNA methylation.

  Gene 20090201

• Haemoglobin F modulation in childhood sickle cell disease.

  British journal of haematology 20090201

• Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.

  Carcinogenesis 20090201

• Estrogen-mediated suppression of the gene encoding protein tyrosine phosphatase PTPRO in human breast cancer: mechanism and role in tamoxifen sensitivity.

  Molecular endocrinology (Baltimore, Md.) 20090201

• Azacitidine enhances sensitivity of platinum-resistant ovarian cancer cells to carboplatin through induction of apoptosis.

  American journal of obstetrics and gynecology 20090201

• The anti-leukemic effect of a novel histone deacetylase inhibitor MCT-1 and 5-aza-cytidine involves augmentation of Nur77 and inhibition of MMP-9 expression.

  International journal of oncology 20090201

• Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.

  Cancer research 20090201

• Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity.

  Journal of immunology (Baltimore, Md. : 1950) 20090201

• Aberrant promoter methylation of SPARC in ovarian cancer.

  Neoplasia (New York, N.Y.) 20090201

• Inactivation of the MAL gene in breast cancer is a common event that predicts benefit from adjuvant chemotherapy.

  Molecular cancer research : MCR 20090201

• Timing of induction of cardiomyocyte differentiation for in vitro cultured mesenchymal stem cells: a perspective for emergencies.

  Canadian journal of physiology and pharmacology 20090201

• Androgen receptor CpG island methylation status in human leukemia cancer cells.

  Cancer investigation 20090201

• Health-related quality of life and symptom assessment in patients with myelodysplastic syndromes.

  Expert review of hematology 20090201

• Epigenetic inactivation of SLIT2 in human hepatocellular carcinomas.

  Biochemical and biophysical research communications 20090130

• Induction of cholinergic differentiation by 5-azacytidine in NG108-15 neuronal cells.

  Neuroreport 20090128

• Concepts of epigenetics in prostate cancer development.

  British journal of cancer 20090127

• Promoter CpG methylation in cancer cells contributes to the regulation of MUC4.

  British journal of cancer 20090127

• Aberrant methylation of candidate tumor suppressor genes in neuroblastoma.

  Cancer letters 20090118

• Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells.

  Oncogene 20090115

• Mechanisms of resistance to 5-aza-2'-deoxycytidine in human cancer cell lines.

  Blood 20090115

• Down-regulation of Rap1GAP via promoter hypermethylation promotes melanoma cell proliferation, survival, and migration.

  Cancer research 20090115

• PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells.

  The Journal of biological chemistry 20090102

• Deleterious CHEK2 1100delC and L303X mutants identified among 38 human breast cancer cell lines.

  Breast cancer research and treatment 20090101

• 5-Azacitidine has limited therapeutic activity in myelofibrosis.

  Leukemia 20090101

• Isolation of mesenchymal stem cells (MSCs) from green fluorescent protein positive (GFP+) transgenic rodents: the grass is not always green(er).

  Stem cells and development 20090101

• Core promoter sequence of SEMG I spans between the two putative GATA-1 binding domains and is responsive to IL-4 and IL-6 in myeloma cells.

  Leukemia research 20090101

• DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma.

  Gut 20090101

• Identification of candidate tumor suppressor genes inactivated by promoter methylation in melanoma.

  Genes, chromosomes & cancer 20090101

• Epigenetic silencing of LRRC3B in colorectal cancer.

  Scandinavian journal of gastroenterology 20090101

• Sensitization by 5-azacytidine toward death receptor-induced hepatic apoptosis.

  The Journal of pharmacology and experimental therapeutics 20090101

• Comparative epigenomics of human and mouse mammary tumors.

  Genes, chromosomes & cancer 20090101

• Induction of intestinalization in human esophageal keratinocytes is a multistep process.

  Carcinogenesis 20090101

• Epigenetic therapy of leukemia: An update.

  The international journal of biochemistry & cell biology 20090101

• 5'-azacytidine expression arrays.

  Methods in molecular biology (Clifton, N.J.) 20090101

• DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells.

  Cancer science 20090101

• Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation.

  Journal of immunology (Baltimore, Md. : 1950) 20090101

• Inhibition of DNA methyltransferase activates tumor necrosis factor alpha-induced monocytic differentiation in acute myeloid leukemia cells.

  Cancer research 20090101

• Senescence induction; a possible cancer therapy.

  Molecular cancer 20090101

• Human concentrative nucleoside transporter 1-mediated uptake of 5-azacytidine enhances DNA demethylation.

  Molecular cancer therapeutics 20090101

• [5-Aza-CdR regulates the expression of RASSF1A gene in human gastric cancer cell line and inhibits the growth of cells].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20090101

• Study of 5-Aza-CdR on transcription regulation of RASSF1A gene in the BIU87 cell line.

  Urologia internationalis 20090101

• Phenotypic instability and epigenetic variability in a diploid potato of hybrid origin, Solanum ruiz-lealii.

  BMC plant biology 20090101

• Integrative analysis of epigenetic modulation in melanoma cell response to decitabine: clinical implications.

  PloS one 20090101

• RTA promoter demethylation and histone acetylation regulation of murine gammaherpesvirus 68 reactivation.

  PloS one 20090101

• Isolation, culture and characterization of cardiac progenitor cells derived from human embryonic heart tubes.

  Cells, tissues, organs 20090101

• The characterization of DNA methylation-mediated regulation of bovine placental lactogen and bovine prolactin-related protein-1 genes.

  BMC molecular biology 20090101

• Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity.

  PloS one 20090101

• Discovery of novel hypermethylated genes in prostate cancer using genomic CpG island microarrays.

  PloS one 20090101

• Microdeletion syndromes disclose replication timing alterations of genes unrelated to the missing DNA.

  Molecular cytogenetics 20090101

• [Effects of cardiotrophin-1 on differentiation of cardiomyocyte-like cells induced from rat bone marrow mesenchymal stem cells].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090101

• Epigenetic modifications of the Estrogen receptor beta gene in epithelial ovarian cancer cells.

  Anticancer research 20090101

• Fenretinide-induced caspase-8 activation and apoptosis in an established model of metastatic neuroblastoma.

  BMC cancer 20090101

• Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells.

  PloS one 20090101

• Heterochromatin protein 1 (HP1) proteins do not drive pericentromeric cohesin enrichment in human cells.

  PloS one 20090101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090101

• Protandim, a fundamentally new antioxidant approach in chemoprevention using mouse two-stage skin carcinogenesis as a model.

  PloS one 20090101

• Quantitation of DNA methylation by melt curve analysis.

  BMC cancer 20090101

• Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20090101

• Challenging issues in molecular-targeted therapy.

  Therapeutics and clinical risk management 20090101

• Counteracting quasispecies adaptability: extinction of a ribavirin-resistant virus mutant by an alternative mutagenic treatment.

  PloS one 20090101

• Phase 1-2a multicenter dose-escalation study of ezatiostat hydrochloride liposomes for injection (Telintra, TLK199), a novel glutathione analog prodrug in patients with myelodysplastic syndrome.

  Journal of hematology & oncology 20090101

• Effect of c-MYC and E2F1 gene silencing and of 5-azacytidine treatment on telomerase activity in pancreatic cancer-derived cell lines.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20090101

• The combination effect of sodium butyrate and 5-Aza-2'-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines.

  World journal of surgical oncology 20090101

• New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer.

  Journal of hematology & oncology 20090101

• Targeted treatment of acute myeloid leukemia in older adults: role of gemtuzumab ozogamicin.

  Clinical interventions in aging 20090101

• Development of DNA methyltransferase inhibitors for the treatment of neoplastic diseases.

  Current medicinal chemistry 20090101

• Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes.

  BMC biology 20090101

• Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations.

  Journal of translational medicine 20090101

• Vorinostat in solid and hematologic malignancies.

  Journal of hematology & oncology 20090101

• 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.

  Molecular cancer 20090101

• Cellular epigenetic modifications of neural stem cell differentiation.

  Cell transplantation 20090101

• Defining and targeting transcription factors in cancer.

  Genome biology 20090101

• Analysis of different routes of administration of heterologous 5-azacytidine-treated mesenchymal stem cells in a porcine model of myocardial infarction.

  Transplantation proceedings 20090101

• Activation of HLA-G expression by 5-aza-2 - deoxycytidine in malignant hematopoetic cells isolated from leukemia patients.

  Neoplasma 20090101

• Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth.

  PloS one 20090101

• A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms.

  PloS one 20090101

• Gravity, a regulation factor in the differentiation of rat bone marrow mesenchymal stem cells.

  Journal of biomedical science 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090101

• Expression and mutation analysis of TIG1 (tazarotene-induced gene 1) in human gastric cancer.

  Oncology research 20090101

• Real-time PCR analysis of genes encoding tumor antigens in esophageal tumors and a cancer vaccine.

  Cancer immunity 20090101

• BCL-6 oncoprotein in breast cancer: loss of expression in disease progression.

  Pathobiology : journal of immunopathology, molecular and cellular biology 20090101

• DNA copy-number loss on 1p36.1 harboring RUNX3 with promoter hypermethylation and associated loss of RUNX3 expression in liver fluke-associated intrahepatic cholangiocarcinoma.

  Asian Pacific journal of cancer prevention : APJCP 20090101

• Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring.

  BMC genomics 20090101

• Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in acute myeloid leukemia.

  Molecular cancer 20090101

• Human bone marrow stem cells co-cultured with neonatal rat cardiomyocytes display limited cardiomyogenic plasticity.

  Cytotherapy 20090101

• Inhibition of myostatin promotes myogenic differentiation of rat bone marrow-derived mesenchymal stromal cells.

  Cytotherapy 20090101

• Human spongiosa mesenchymal stem cells fail to generate cardiomyocytes in vitro.

  Journal of negative results in biomedicine 20090101

• Fas expression in metastatic osteosarcoma cells is not regulated by CpG island methylation.

  Oncology research 20090101

• Azacitidine: a review of its use in higher-risk myelodysplastic syndromes/acute myeloid leukaemia.

  Drugs 20090101

• Troglitazone reverses the multiple drug resistance phenotype in cancer cells.

  Drug design, development and therapy 20090101

• Silencing of claudin-11 is associated with increased invasiveness of gastric cancer cells.

  PloS one 20090101

• Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies.

  Retrovirology 20090101

• Managing myelodysplastic symptoms in elderly patients.

  Clinical interventions in aging 20090101

• Fetal globin induction in beta-thalassemia.

  Hemoglobin 20090101

• Treatment of MDS: something old, something new, something borrowed..

  Hematology. American Society of Hematology. Education Program 20090101

• Global demethylation of rat chondrosarcoma cells after treatment with 5-aza-2'-deoxycytidine results in increased tumorigenicity.

  PloS one 20090101

• Potential impact of stress activated retrotransposons on genome evolution in a marine diatom.

  BMC genomics 20090101

• Management of myelodysplastic syndromes in the geriatric patient.

  Current hematologic malignancy reports 20090101

• Myelodysplastic syndrome: An update on diagnosis and therapy.

  Current hematologic malignancy reports 20090101

• Hematopoietic stem cell transplantation in patients with myelodysplastic syndrome.

  F1000 medicine reports 20090101

• The role of azacitidine in the management of myelodysplastic syndromes (MDS).

  Cancer management and research 20090101

• The importance of epigenetic alterations in the development of epstein-barr virus-related lymphomas.

  Mediterranean journal of hematology and infectious diseases 20090101

• EBV in Hodgkin Lymphoma.

  Mediterranean journal of hematology and infectious diseases 20090101

• Beneficial effects of population bottlenecks in an RNA virus evolving at increased error rate.

  Journal of molecular biology 20081231

• Mature adipocyte-derived dedifferentiated fat cells can transdifferentiate into skeletal myocytes in vitro.

  Biochemical and biophysical research communications 20081219

• Identification of PMF1 methylation in association with bladder cancer progression.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081215

• Methyl-CpG targeted transcriptional activation allows re-expression of tumor suppressor genes in human cancer cells.

  Biochemical and biophysical research communications 20081212

• Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer.

  Biochemical and biophysical research communications 20081212

• Regulation of cyclin D1 and Wnt10b gene expression by cAMP-responsive element-binding protein during early adipogenesis involves differential promoter methylation.

  The Journal of biological chemistry 20081212

• Inhibition of DNA methyltransferase activity upregulates Fyn tyrosine kinase expression in Hut-78 T-lymphoma cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201

• Semenogelin I expression in myeloma cells can be upregulated pharmacologically.

  Leukemia research 20081201

• Alleviation of myelodysplastic syndrome-associated skin rush after treatment with decitabine.

  European journal of haematology 20081201

• Predictive value of expression and promoter hypermethylation of XAF1 in hepatitis B virus-associated hepatocellular carcinoma treated with transplantation.

  Annals of surgical oncology 20081201

• Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma.

  Experimental hematology 20081201

• Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro.

  Cancer biology & therapy 20081201

• Differentiation of human adipose-derived stem cells towards cardiomyocytes is facilitated by laminin.

  Cell and tissue research 20081201

• Aberrant methylation of ADAMTS1 in non-small cell lung cancer.

  Cancer genetics and cytogenetics 20081201

• Are new agents really making a difference in MDS?

  Best practice & research. Clinical haematology 20081201

• Epigenetic inactivation of galanin receptor 1 in head and neck cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081201

• In vitro effects of low-level laser irradiation for bone marrow mesenchymal stem cells: proliferation, growth factors secretion and myogenic differentiation.

  Lasers in surgery and medicine 20081201

• [Effects of 5-Aza-2'-deoxycytidine and trichostatin A on DNA methylation and expression of hMLH1 in ovarian cancer cell line COC1/DDP].

  Ai zheng = Aizheng = Chinese journal of cancer 20081201

• Gateways to clinical trials. December 2008.

  Methods and findings in experimental and clinical pharmacology 20081201

• Recent advances in low- and intermediate-1-risk myelodysplastic syndrome: developing a consensus for optimal therapy.

  Clinical advances in hematology & oncology : H&O 20081201

• Epigenetic perturbations in the pathogenesis of mustard toxicity; hypothesis and preliminary results.

  Interdisciplinary toxicology 20081201

• Nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) expression is increased by the histone deacetylase inhibitor trichostatin A.

  The Journal of biological chemistry 20081128

• PCFT/SLC46A1 promoter methylation and restoration of gene expression in human leukemia cells.

  Biochemical and biophysical research communications 20081128

• Promoter hypermethylation of CDH13 is a common, early event in human esophageal adenocarcinogenesis and correlates with clinical risk factors.

  International journal of cancer 20081115

• p53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia.

  Cancer research 20081115

• Management of myelodysplastic syndromes: 2008 update.

  Oncology (Williston Park, N.Y.) 20081115

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• Epigenetic mechanisms and Sp1 regulate mitochondrial citrate carrier gene expression.

  Biochemical and biophysical research communications 20081107

• Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-gamma in promyelocytic cells.

  International immunology 20081101

• Demethylating agents in myeloid malignancies.

  Current opinion in oncology 20081101

• PAX4 has the potential to function as a tumor suppressor in human melanoma.

  International journal of oncology 20081101

• The aberrant promoter methylation of BMP3b and BMP6 in malignant pleural mesotheliomas.

  Oncology reports 20081101

• Involvement of epigenetic mechanisms in the regulation of secreted phospholipase A2 expressions in Jurkat leukemia cells.

  Neoplasia (New York, N.Y.) 20081101

• AZGP1 autoantibody predicts survival and histone deacetylase inhibitors increase expression in lung adenocarcinoma.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081101

• Hydroxyurea, azacitidine and gemtuzumab ozogamicin therapy in patients with previously untreated non-M3 acute myeloid leukemia and high-risk myelodysplastic syndromes in the elderly: results from a pilot trial.

  Leukemia & lymphoma 20081101

• DNA hypomethylation therapies and hemoglobin disorders. [An interview with Hassana Fathallah by H&O].

  Clinical advances in hematology & oncology : H&O 20081101

• New agents for the treatment of AML recent study findings.

  Clinical advances in hematology & oncology : H&O 20081101

• Future research directions for the treatment of AML.

  Clinical advances in hematology & oncology : H&O 20081101

• [The expression of GATA-4 and Nkx2.5 gene in the transformation of Rattus mesenchymal stem cells into cardiomyocytes].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20081101

• T-2 toxin-induced toxicity in pregnant mice and rats.

  International journal of molecular sciences 20081101

• [Myelodysplastic syndromes: therapeutic advances and promising future].

  Medicina clinica 20081018

• Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.

  International journal of cancer 20081015

• Promoter methylation of the bone morphogenetic protein-6 gene in association with adult T-cell leukemia.

  International journal of cancer 20081015

• Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.

  Blood 20081001

• Promoter hypomethylation regulates CD133 expression in human gliomas.

  Cell research 20081001

• Combination of 5-azacytidine and thalidomide for the treatment of myelodysplastic syndromes and acute myeloid leukemia.

  Cancer 20081001

• Decitabine as 'bridge therapy' to a MUD transplant in relapsed AML postautologous stem cell transplantation.

  American journal of hematology 20081001

• Highly efficient regioselective synthesis of 5'-O-lauroyl-5-azacytidine catalyzed by Candida antarctica Lipase B.

  Applied biochemistry and biotechnology 20081001

• In utero supplementation with methyl donors enhances allergic airway disease in mice.

  The Journal of clinical investigation 20081001

• Changing the treatment paradigm in myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20081001

• Treatment strategies to optimize clinical benefit in the patient with myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20081001

• Future directions in myelodysplastic syndrome: newer agents and the role of combination approaches.

  Cancer control : journal of the Moffitt Cancer Center 20081001

• Histone deacetylase inhibitor scriptaid induces cell cycle arrest and epigenetic change in colon cancer cells.

  International journal of oncology 20081001

• Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081001

• Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.

  Cancer research 20081001

• [Pathogenesis of and therapeutic progress for myelodysplastic syndromes].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001

• [Epigenetics in hematological disorders].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001

• The costs of drugs used to treat myelodysplastic syndromes following National Comprehensive Cancer Network Guidelines.

  Journal of the National Comprehensive Cancer Network : JNCCN 20081001

• Expression and promoter methylation status of mismatch repair gene hMLH1 and hMSH2 in epithelial ovarian cancer.

  The Australian & New Zealand journal of obstetrics & gynaecology 20081001

• The high rate of endoreduplication in the repair deficient CHO mutant EM9 parallels a reduced level of methylated deoxycytidine in DNA.

  Mutation research 20080926

• [Histone H3 lysine 9 methylation is associated with the expression of hMLH1 and DNA methylation in gastric cancer cells].

  Zhonghua yi xue za zhi 20080916

• Will histone deacetylase inhibitors require combination with other agents to fulfil their therapeutic potential?

  British journal of cancer 20080902

• Trichostatin A and 5 Aza-2' deoxycytidine decrease estrogen receptor mRNA stability in ER positive MCF7 cells through modulation of HuR.

  Breast cancer research and treatment 20080901

• Evaluation of a functional epigenetic approach to identify promoter region methylation in phaeochromocytoma and neuroblastoma.

  Endocrine-related cancer 20080901

• Deoxyribonucleic acid methyltransferase 3B promotes epigenetic silencing through histone 3 chromatin modifications in pituitary cells.

  The Journal of clinical endocrinology and metabolism 20080901

• A pilot pharmacokinetic study of oral azacitidine.

  Leukemia 20080901

• Genetic and epigenetic inactivation of T-cadherin in human hepatocellular carcinoma cells.

  International journal of cancer 20080901

• Increased pre-implantation development of cloned bovine embryos treated with 5-aza-2'-deoxycytidine and trichostatin A.

  Theriogenology 20080901

• Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis.

  Molecular and cellular biology 20080901

• Discovery of myopodin methylation in bladder cancer.

  The Journal of pathology 20080901

• Potential link between estrogen receptor-alpha gene hypomethylation and uterine fibroid formation.

  Molecular human reproduction 20080901

• LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.

  Cancer research 20080901

• Azacytidine causes complex DNA methylation responses in myeloid leukemia.

  Molecular cancer therapeutics 20080901

• Alterations of constitutive pericentromeric heterochromatin in lymphocytes of cancer patients and lymphocytes exposed to 5-azacytidine is associated with DNA-hypomethylation.

  Experimental oncology 20080901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080901

• Cancer prevention: epigenetics steps up to the plate.

  Cancer prevention research (Philadelphia, Pa.) 20080901

• [5-aza-2'-deoxycytidine induces changes of histone H3-lysine 9 methylation in bladder tumor cells].

  Zhonghua yi xue za zhi 20080819

• Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues.

  Biochemical and biophysical research communications 20080815

• 2'-Deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]-5-azacytidine: a novel inhibitor of DNA methyltransferase that requires activation by human carboxylesterase 1.

  Cancer letters 20080808

• CCCTC-binding factor activates PARP-1 affecting DNA methylation machinery.

  The Journal of biological chemistry 20080808

• Plasma pharmacokinetics and oral bioavailability of 3,4,5,6-tetrahydrouridine, a cytidine deaminase inhibitor, in mice.

  Cancer chemotherapy and pharmacology 20080801

• ER alpha negative breast cancer cells restore response to endocrine therapy by combination treatment with both HDAC inhibitor and DNMT inhibitor.

  Journal of cancer research and clinical oncology 20080801

• Curcumin downregulates H19 gene transcription in tumor cells.

  Journal of cellular biochemistry 20080801

• Current status of epigenetic treatment in myelodysplastic syndromes.

  Annals of hematology 20080801

• DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines.

  International journal of cancer 20080801

• Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells.

  International journal of cancer 20080801

• Epigenetic remodeling during arsenical-induced malignant transformation.

  Carcinogenesis 20080801

• Intracerebral transplantation of human adipose tissue stromal cells after middle cerebral artery occlusion in rats.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20080801

• 5-Azacytidine-treated human mesenchymal stem/progenitor cells derived from umbilical cord, cord blood and bone marrow do not generate cardiomyocytes in vitro at high frequencies.

  Vox sanguinis 20080801

• Epigenetic inheritance of DNA methylation limits activation-induced expression of FOXP3 in conventional human CD25-CD4+ T cells.

  International immunology 20080801

• 5-Aza-2'-deoxycytidine restores proapoptotic function of p53 in cancer cells resistant to p53-induced apoptosis.

  Cancer investigation 20080801

• Azacitidine and the beginnings of therapeutic epigenetic modulation.

  Expert opinion on pharmacotherapy 20080801

• Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells.

  International journal of oncology 20080801

• Analysis of the methylation status of genes up-regulated by the demethylating agent, 5-aza-2'-deoxycytidine, in esophageal squamous cell carcinoma.

  Oncology reports 20080801

• Epigenetic identification of ubiquitin carboxyl-terminal hydrolase L1 as a functional tumor suppressor and biomarker for hepatocellular carcinoma and other digestive tumors.

  Hepatology (Baltimore, Md.) 20080801

• Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus.

  PLoS genetics 20080801

• New drugs in acute myeloid leukemia.

  Seminars in oncology 20080801

• [Effect of decitabine combined with Trichostatin A on MDS cell line SKM-1 in vitro].

  Zhongguo shi yan xue ye xue za zhi 20080801

• Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment.

  Journal of endocrinological investigation 20080801

• Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas.

  Genes & genetic systems 20080801

• [Hypomethylation of 5'CpG island of insulin-like growth factor binding protein-related protein 1 is associated with its overexpression in colorectal cancer].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20080801

• Epigenetic silencing of AXIN2/betaTrCP and deregulation of p53-mediated control lead to wild-type beta-catenin nuclear accumulation in lung tumorigenesis.

  Oncogene 20080724

• Synthesis and antiproliferative activities of 5-azacytidine analogues in human leukemia cells.

  Molecules (Basel, Switzerland) 20080723

• Persistent downregulation of the pancarcinoma-associated epithelial cell adhesion molecule via active intranuclear methylation.

  International journal of cancer 20080715

• Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma.

  International journal of cancer 20080715

• A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts.

  Cell cycle (Georgetown, Tex.) 20080715

• Dissecting direct reprogramming through integrative genomic analysis.

  Nature 20080703

• CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas.

  Journal of the National Cancer Institute 20080702

• Cytogenetic features in myelodysplastic syndromes.

  Annals of hematology 20080701

• Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine.

  International journal of cancer 20080701

• Acute myeloid leukemia in the elderly: conventional and novel treatment approaches.

  Blood reviews 20080701

• Incubation with somatostatin, 5-aza decitabine and trichostatin up-regulates somatostatin receptor expression in prostate cancer cells.

  Oncology reports 20080701

• Histone H3 (lys-9) deacetylation is associated with transcriptional silencing of E-cadherin in colorectal cancer cell lines.

  Cancer investigation 20080701

• [Promoter methylation regulates KIR3DL1 gene expression in NK-92MI cell line].

  Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20080701

• Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines.

  Science in China. Series C, Life sciences 20080701

• [Differences between adipose-derived stem cells and mesenchymal stem cells in differentiation into cardiomyocytes].

  Sheng li xue bao : [Acta physiologica Sinica] 20080625

• Proteins that bind methylated DNA and human cancer: reading the wrong words.

  British journal of cancer 20080617

• Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma.

  Cancer research 20080615

• ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080615

• Down-regulation of hedgehog-interacting protein through genetic and epigenetic alterations in human hepatocellular carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080615

• Induction of MHC class I-related chain B (MICB) by 5-aza-2'-deoxycytidine.

  Biochemical and biophysical research communications 20080613

• SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.

  British journal of cancer 20080603

• Five azacytidine, a DNA methyltransferase inhibitor, specifically inhibits testicular cord formation and Sertoli cell differentiation in vitro.

  Molecular reproduction and development 20080601

• Epigenetic-based treatments emphasize the biologic differences of core-binding factor acute myeloid leukemias.

  Leukemia research 20080601

• The DNA demethylating agent 5-aza-2'-deoxycytidine activates NY-ESO-1 antigenicity in orthotopic human glioma.

  International journal of cancer 20080601

• Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies.

  Cancer 20080601

• Oct4 is epigenetically regulated by methylation in normal placenta and gestational trophoblastic disease.

  Placenta 20080601

• The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma.

  Haematologica 20080601

• DNA methylation controls Foxp3 gene expression.

  European journal of immunology 20080601

• Generalized granuloma annulare as an initial manifestation of chronic myelomonocytic leukemia: a report of 2 cases.

  The American Journal of dermatopathology 20080601

• Epigenetic modification is involved in aberrant expression of class III beta-tubulin, TUBB3, in ovarian cancer cells.

  International journal of oncology 20080601

• Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells.

  Cancer research 20080601

• The human receptor tyrosine kinase Axl gene--promoter characterization and regulation of constitutive expression by Sp1, Sp3 and CpG methylation.

  Bioscience reports 20080601

• Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias.

  Current medicinal chemistry 20080601

• Demethylating agent 5-aza-2'-deoxycytidine enhances susceptibility of bladder transitional cell carcinoma to Cisplatin.

  Urology 20080601

• Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

  Cancer cell 20080601

• DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.

  Cancer cell 20080601

• [DNA methylation regulates kir3dl1 gene expression in K562 cell line].

  Zhongguo shi yan xue ye xue za zhi 20080601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080601

• Pharmaceutical approval update.

  P & T : a peer-reviewed journal for formulary management 20080601

• Investigation of transcriptional gene silencing and mechanism induced by shRNAs targeted to RUNX3 in vitro.

  World journal of gastroenterology 20080521

• Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells.

  The Prostate 20080515

• Effects of cellular differentiation, chromosomal integration and 5-aza-2'-deoxycytidine treatment on human papillomavirus-16 DNA methylation in cultured cell lines.

  Virology 20080510

• Relationship between DNA methylation states and transcription of individual isoforms encoded by the protocadherin-alpha gene cluster.

  The Journal of biological chemistry 20080502

• An epigenetic disorder may cause aberrant expression of aromatase gene in endometriotic stromal cells.

  Fertility and sterility 20080501

• DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity.

  Neurobiology of learning and memory 20080501

• Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells.

  Leukemia research 20080501

• DNA hypomethylation circuit of the mouse oocyte-specific histone H1foo gene in female germ cell lineage.

  Biology of reproduction 20080501

• A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis.

  Leukemia 20080501

• Epigenetic and HIF-1 regulation of stanniocalcin-2 expression in human cancer cells.

  Experimental cell research 20080501

• Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage.

  Experimental cell research 20080501

• Reduced T-cadherin expression and promoter methylation are associated with the development and progression of hepatocellular carcinoma.

  International journal of oncology 20080501

• ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation.

  Autoimmunity 20080501

• Internuclear gene silencing in Phytophthora infestans is established through chromatin remodelling.

  Microbiology (Reading, England) 20080501

• Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.

  Neoplasia (New York, N.Y.) 20080501

• Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor.

  Molecular cancer therapeutics 20080501

• DNA methylation in T cells from idiopathic lupus and drug-induced lupus patients.

  Autoimmunity reviews 20080501

• TLS-ERG leukemia fusion protein deregulates cyclin-dependent kinase 1 and blocks terminal differentiation of myeloid progenitor cells.

  Molecular cancer research : MCR 20080501

• Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer.

  British journal of cancer 20080422

• Global genomic methylation levels in the liver and gonads of the three-spine stickleback (Gasterosteus aculeatus) after exposure to hexabromocyclododecane and 17-beta oestradiol.

  Environment international 20080401

• Pharmacokinetics of decitabine administered as a 3-h infusion to patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

  Cancer chemotherapy and pharmacology 20080401

• Mechanisms of DNA breaks induction in vivo by 5-azacytidine: paths of micronucleus induction by azaC.

  Journal of applied toxicology : JAT 20080401

• Efficacy of decitabine in the treatment of patients with chronic myelomonocytic leukemia (CMML).

  Leukemia research 20080401

• V1a vasopressin receptor expression is modulated during myogenic differentiation.

  Differentiation; research in biological diversity 20080401

• 5-Aza-2'-deoxycytidine suppresses human renal carcinoma cell growth in a xenograft model via up-regulation of the connexin 32 gene.

  British journal of pharmacology 20080401

• Epigenetic silencing of maspin expression occurs early in the conversion of keratocytes to fibroblasts.

  Experimental eye research 20080401

• Clinical effectiveness of decitabine in severe sickle cell disease.

  British journal of haematology 20080401

• Analysis of protein domains and Rett syndrome mutations indicate that multiple regions influence chromatin-binding dynamics of the chromatin-associated protein MECP2 in vivo.

  Journal of cell science 20080401

• Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a: results of cancer and leukemia group B 159904.

  Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401

• Methylation silencing of transforming growth factor-beta receptor type II in rat prostate cancers.

  Cancer research 20080401

• DNA methyltransferase inhibitors: class effect or unique agents?

  Leukemia & lymphoma 20080401

• Activity of decitabine in patients with myelodysplastic syndrome previously treated with azacitidine.

  Leukemia & lymphoma 20080401

• Selective POTE paralogs on chromosome 2 are expressed in human embryonic stem cells.

  Stem cells and development 20080401

• The role of DNA hypermethylation and demethylation in cancer and cancer therapy.

  Current oncology (Toronto, Ont.) 20080401

• [Analysis of in vitro anti-leukemia effect of 5-aza-2'-deoxycitydine].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080401

• The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage.

  BMB reports 20080331

• The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.

  Oncogene 20080327

• 5-Aza-2'-deoxycytidine increases the expression of anti-angiogenic vascular endothelial growth factor 189b variant in human lung microvascular endothelial cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301

• DNA methyltransferase 3B (DNMT3B) mutations in ICF syndrome lead to altered epigenetic modifications and aberrant expression of genes regulating development, neurogenesis and immune function.

  Human molecular genetics 20080301

• Promoting effect of 5-azacytidine on the myogenic differentiation of bone marrow stromal cells.

  European journal of cell biology 20080301

• Supportive care, growth factors, and new therapies in myelodysplastic syndromes.

  Blood reviews 20080301

• Promoter-targeted siRNAs induce gene silencing of simian immunodeficiency virus (SIV) infection in vitro.

  Molecular therapy : the journal of the American Society of Gene Therapy 20080301

• Cardiomyogenic potential of human adult bone marrow mesenchymal stem cells in vitro.

  The Thoracic and cardiovascular surgeon 20080301

• Homocysteine-induced extracellular superoxide dismutase and its epigenetic mechanisms in monocytes.

  The Journal of experimental biology 20080301

• Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.

  Neoplasia (New York, N.Y.) 20080301

• [Pathophysiology, diagnosis and treatment of anemia].

  Nihon rinsho. Japanese journal of clinical medicine 20080301

• [Myelodysplastic syndrome].

  Nihon rinsho. Japanese journal of clinical medicine 20080301

• SIRT1 inhibition alleviates gene silencing in Fragile X mental retardation syndrome.

  PLoS genetics 20080301

• The epigenetic origin of aneuploidy.

  Current genomics 20080301

• Expression of BORIS in melanoma: lack of association with MAGE-A1 activation.

  International journal of cancer 20080215

• Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells.

  Biochemical pharmacology 20080215

• Induction of hypomethylation and molecular response after decitabine therapy in patients with chronic myelomonocytic leukemia.

  Blood 20080215

• Tricyclic HIV integrase inhibitors: potent and orally bioavailable C5-aza analogs.

  Bioorganic & medicinal chemistry letters 20080215

• Simultaneous determination of decitabine and vorinostat (Suberoylanalide hydroxamic acid, SAHA) by liquid chromatography tandem mass spectrometry for clinical studies.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215

• DNA methylation and mechanism of action of 5-azacytidine.

  Blood 20080215

• Differential epigenetic regulation of Aiolos expression in human tumoral cell lines and primary cells.

  FEBS letters 20080206

• Three-dimensional epidermis-like growth of human mesenchymal stem cells on dermal equivalents: contribution to tissue organization by adaptation of myofibroblastic phenotype and function.

  Differentiation; research in biological diversity 20080201

• Induction of MHC class I molecule cell surface expression and epigenetic activation of antigen-processing machinery components in a murine model for human papilloma virus 16-associated tumours.

  Immunology 20080201

• An ATM- and Rad3-related (ATR) signaling pathway and a phosphorylation-acetylation cascade are involved in activation of p53/p21Waf1/Cip1 in response to 5-aza-2'-deoxycytidine treatment.

  The Journal of biological chemistry 20080201

• Genome-wide demethylation promotes triplet repeat instability independently of homologous recombination.

  DNA repair 20080201

• DNA demethylation and histone deacetylation inhibition co-operate to re-express estrogen receptor beta and induce apoptosis in prostate cancer cell-lines.

  The Prostate 20080201

• Drugs affecting prelamin A processing: effects on heterochromatin organization.

  Experimental cell research 20080201

• Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells.

  Experimental hematology 20080201

• [Effect of (-)-epigallocatechin-3-gallate and 5-AZA-CdR on expression of X-linked inhibitor of apoptosis protein-associated factor 1 in human leukemia HL-60 and K562 cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080201

• Solving the mystery of myelodysplasia.

  PLoS medicine 20080201

• Epigenetic down-regulation and suppressive role of DCBLD2 in gastric cancer cell proliferation and invasion.

  Molecular cancer research : MCR 20080201

• DNMT1 as a molecular target in a multimodality-resistant phenotype in tumor cells.

  Molecular cancer research : MCR 20080201

• [Methylation of PTPRG gene and its regulation in gastric cancer].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080201

• Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays.

  British journal of cancer 20080129

• Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma.

  British journal of cancer 20080129

• Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer.

  British journal of cancer 20080129

• Regulation of demethylation and re-expression of RASSF1A gene in gastric cancer cell lines by combined treatment of 5-Aza-CdR and NaB.

  World journal of gastroenterology 20080128

• Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

  Journal of medicinal chemistry 20080124

• Reversal of methylation silencing of Apo2L/TRAIL receptor 1 (DR4) expression overcomes resistance of SK-MEL-3 and SK-MEL-28 melanoma cells to interferons (IFNs) or Apo2L/TRAIL.

  Oncogene 20080117

• Epigenetic regulation of microRNA-370 by interleukin-6 in malignant human cholangiocytes.

  Oncogene 20080110

• Epigenetic silencing of telomerase and a non-alkylating agent as a novel therapeutic approach for glioma.

  Brain research 20080110

• Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080109

• PU.1 is dispensable to block erythroid differentiation in Friend erythroleukemia cells.

  Leukemia research 20080101

• PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes.

  Leukemia 20080101

• Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin.

  Blood 20080101

• Epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer.

  The Journal of pathology 20080101

• Promoter methylation is associated with the age-dependent loss of N-cadherin in the rat kidney.

  American journal of physiology. Renal physiology 20080101

• DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B.

  Molecular and cellular biology 20080101

• Hypermethylation of the somatostatin promoter is a common, early event in human esophageal carcinogenesis.

  Cancer 20080101

• CpG methylation plays a vital role in determining tissue- and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding.

  Nucleic acids research 20080101

• Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription.

  Nature cell biology 20080101

• Human chromosome fragility.

  Biochimica et biophysica acta 20080101

• Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients.

  Acta pharmacologica Sinica 20080101

• Genome-wide transcriptional response to 5-aza-2'-deoxycytidine and trichostatin a in multiple myeloma cells.

  Cancer research 20080101

• Tandem repeat mutation, global DNA methylation, and regulation of DNA methyltransferases in cultured mouse embryonic fibroblast cells chronically exposed to chemicals with different modes of action.

  Environmental and molecular mutagenesis 20080101

• Myelodysplastic syndromes: introduction.

  Seminars in hematology 20080101

• DNA methyltransferase and histone deacetylase inhibitors in the treatment of myelodysplastic syndromes.

  Seminars in hematology 20080101

• Targeted therapies in myelodysplastic syndrome.

  Seminars in hematology 20080101

• DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines.

  Molecular cancer 20080101

• Reactivation of inactive X chromosome: a potential culprit and therapeutic target for systemic lupus erythematosus.

  Medical hypotheses 20080101

• Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates.

  PloS one 20080101

• Pharmacogenomics and therapeutics of hemoglobinopathies.

  Hemoglobin 20080101

• Inositide signaling: Nuclear targets and involvement in myelodysplastic syndromes.

  Advances in enzyme regulation 20080101

• FOXP3 promoter demethylation reveals the committed Treg population in humans.

  PloS one 20080101

• Common variants within MECP2 confer risk of systemic lupus erythematosus.

  PloS one 20080101

• Cell type-specific activation of the cytomegalovirus promoter by dimethylsulfoxide and 5-aza-2'-deoxycytidine.

  The international journal of biochemistry & cell biology 20080101

• DNA demethylation-dependent enhancement of toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription.

  BMC molecular biology 20080101

• HIV-1 latency in actively dividing human T cell lines.

  Retrovirology 20080101

• Importance of dose-schedule of 5-aza-2'-deoxycytidine for epigenetic therapy of cancer.

  BMC cancer 20080101

• Genomic imprinting of IGF2 in marsupials is methylation dependent.

  BMC genomics 20080101

• Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors.

  Breast cancer research : BCR 20080101

• Comparative study of mesenchymal stem cells from C57BL/10 and mdx mice.

  BMC cell biology 20080101

• Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors.

  Molecular cancer 20080101

• Epigenetic modification of histone 3 at lysine 9 in sheep zygotes and its relationship with DNA methylation.

  BMC developmental biology 20080101

• Anticancer drug discovery targeting DNA hypermethylation.

  Current medicinal chemistry 20080101

• Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma.

  BMC cancer 20080101

• Isolation and characterization of side population stem cells in articular synovial tissue.

  BMC musculoskeletal disorders 20080101

• Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma.

  Pathobiology : journal of immunopathology, molecular and cellular biology 20080101

• HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.

  PloS one 20080101

• A cytosine methyltransferase homologue is essential for sexual development in Aspergillus nidulans.

  PloS one 20080101

• Journal of hematology & oncology: a journal open to all.

  Journal of hematology & oncology 20080101

• Phenylhexyl isothiocyanate has dual function as histone deacetylase inhibitor and hypomethylating agent and can inhibit myeloma cell growth by targeting critical pathways.

  Journal of hematology & oncology 20080101

• Age-specific epigenetic drift in late-onset Alzheimer's disease.

  PloS one 20080101

• [Growth and differentiation of cell hybrids obtained by fusing mouse PCC4azal teratocarcinoma cells and mouse spleen cells under different in vitro culture conditions].

  Ontogenez 20080101

• Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection.

  BMC evolutionary biology 20080101

• Prevention of murine experimental corneal trauma by epigenetic events regulating claudin 6 and claudin 9.

  Japanese journal of ophthalmology 20080101

• Epigenetic mechanisms involved in differential MDR1 mRNA expression between gastric and colon cancer cell lines and rationales for clinical chemotherapy.

  BMC gastroenterology 20080101

• A patient with glycogen storage disease type Ib presenting with acute myeloid leukemia (AML) bearing monosomy 7 and translocation t(3;8)(q26;q24) after 14 years of treatment with granulocyte colony-stimulating factor (G-CSF): a case report.

  Journal of medical case reports 20080101

• DNA methylation: its role in cancer development and therapy.

  Current problems in cancer 20080101

• Synergistic effect of 5-Aza-2'-deoxycytidine and genistein in combination against leukemia.

  Oncology research 20080101

• Methylation of WTH3, a possible drug resistant gene, inhibits p53 regulated expression.

  BMC cancer 20080101

• The fungus Neurospora crassa displays telomeric silencing mediated by multiple sirtuins and by methylation of histone H3 lysine 9.

  Epigenetics & chromatin 20080101

• Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay.

  PloS one 20080101

• Ovarian cancer plasticity and epigenomics in the acquisition of a stem-like phenotype.

  Journal of ovarian research 20080101

• Mechanisms of metastasis.

  Breast cancer research : BCR 20080101

• Aberrant allele-specific replication, independent of parental origin, in blood cells of cancer patients.

  BMC cancer 20080101

• Epigenetic deregulation through DNA demethylation seems not to interfere with the differentiation of epithelia from pre-gastrulating rat embryos in vitro.

  Acta dermatovenerologica Croatica : ADC 20080101

• [The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)].

  Tsitologiia 20080101

• In vitro cardiogenesis can be initiated in human CD34+ cells.

  Indian heart journal 20080101

• [Osteogenesis of human vascular endothelial cells in culture].

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20080101

• Epigenetics, behaviour, and health.

  Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101

• The effects of continued azacitidine treatment cycles on response in higher risk patients with myelodysplastic syndromes: an update.

  Ecancermedicalscience 20080101

• Azacitidine prolongs overall survival and reduces infections and hospitalizations in patients with WHO-defined acute myeloid leukaemia compared with conventional care regimens: an update.

  Ecancermedicalscience 20080101

• [Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell].

  Zhonghua yi xue za zhi 20071225

• Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines.

  World journal of gastroenterology 20071214

• PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation.

  Oncogene 20071213

• Epigenetic regulation of leptin affects MMP-13 expression in osteoarthritic chondrocytes: possible molecular target for osteoarthritis therapeutic intervention.

  Annals of the rheumatic diseases 20071201

• Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression.

  Hepatology research : the official journal of the Japan Society of Hepatology 20071201

• Epigenetic dysregulation of Wnt signaling pathway in multiple myeloma.

  Leukemia 20071201

• Downregulation of microRNAs-143 and -145 in B-cell malignancies.

  Cancer science 20071201

• Downregulation of several fibulin genes in prostate cancer.

  The Prostate 20071201

• Inducible expression of a prostate cancer-testis antigen, SSX-2, following treatment with a DNA methylation inhibitor.

  The Prostate 20071201

• DNA hypomethylation is crucial for apoptotic DNA to induce systemic lupus erythematosus-like autoimmune disease in SLE-non-susceptible mice.

  Rheumatology (Oxford, England) 20071201

• Azacitidine-associated hyperthermia and interstitial pneumonitis in a patient with myelodysplastic syndrome.

  Pharmacotherapy 20071201

• The role of azacitidine in the treatment of myelodysplastic syndromes.

  Expert opinion on investigational drugs 20071201

• Promoter hypermethylation of the RUNX3 gene in esophageal squamous cell carcinoma.

  Cancer investigation 20071201

• [5-azacytidine enhances anti-tumor efficacy of doxorubicin to neuroblastoma cell lines].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201

• [MicroRNAs can be expressed in cardiomyocyte-like cells differentiated from human mesenchymal stem cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071201

• Phase II study of azacitidine to restore responsiveness of prostate cancer to hormonal therapy.

  Clinical genitourinary cancer 20071201

• [In vitro differentiation of rat mesenchymal stem cells into skeletal muscle cells induced by myoblast differentiation factor and 5-azacytidine].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20071201

• Epigenetic lesions in malignant melanoma.

  Current pharmaceutical biotechnology 20071201

• Targeted therapies in the management of metastatic bladder cancer.

  Biologics : targets & therapy 20071201

• Study of the degradation of 5-azacytidine as a model of unstable drugs using a stopped-flow method and further data analysis with multivariate curve resolution.

  Talanta 20071130

• Metastatic suppressor genes inactivated by aberrant methylation in gastric cancer.

  World journal of gastroenterology 20071121

• Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours.

  British journal of cancer 20071119

• Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene.

  Blood 20071115

• The similar effect of transplantation of marrow-derived mesenchymal stem cells with or without prior differentiation induction in experimental myocardial infarction.

  Journal of biomedical science 20071101

• Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis.

  American journal of hematology 20071101

• Demethylation of CD40LG on the inactive X in T cells from women with lupus.

  Journal of immunology (Baltimore, Md. : 1950) 20071101

• Multidimensional liquid phase protein separations in conjunction with stable isotope labelling for quantitative proteomics.

  Proteomics 20071101

• Determining the global DNA methylation status of rat according to the identifier repetitive elements.

  Electrophoresis 20071101

• p300 expression repression by hypermethylation associated with tumour invasion and metastasis in oesophageal squamous cell carcinoma.

  Journal of clinical pathology 20071101

• Increased iodine uptake in thyroid carcinoma after treatment with sodium butyrate and decitabine (5-Aza-dC).

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20071101

• The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.

  The American journal of pathology 20071101

• Regulation of the CLDN3 gene in ovarian cancer cells.

  Cancer biology & therapy 20071101

• [Aberrant methylation of tumor suppressor genes in renal cell carcinoma].

  Ai zheng = Aizheng = Chinese journal of cancer 20071101

• Hypomethylation and aberrant expression of the glioma pathogenesis-related 1 gene in Wilms tumors.

  Neoplasia (New York, N.Y.) 20071101

• Treatment options in advanced myelodysplastic syndrome, with emphasis on epigenetic therapy.

  International journal of hematology 20071101

• Evaluating new treatment options for MDS.

  Clinical advances in hematology & oncology : H&O 20071101

• Induction of flowering by 5-azacytidine in some plant species: relationship between the stability of photoperiodically induced flowering and flower-inducing effect of DNA demethylation.

  Physiologia plantarum 20071101

• [Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071101

• ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations.

  FEBS letters 20071030

• Promoter-independent regulation of vimentin expression in mammary epithelial cells by val(12)ras and TGFbeta.

  Experimental cell research 20071015

• Nucleotide excision repair and homologous recombination systems commit differentially to the repair of DNA-protein crosslinks.

  Molecular cell 20071012

• Combining epigenetic and cytotoxic therapy in the treatment of solid tumors.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010

• Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071010

• Frequent epigenetic inactivation of secreted frizzled-related protein 2 (SFRP2) by promoter methylation in human gastric cancer.

  British journal of cancer 20071008

• Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

  Oncogene 20071004

• Downregulation of connexin 43 in nasopharyngeal carcinoma cells is related to promoter methylation.

  Oral oncology 20071001

• Interconversion of intra- and extra-chromosomal sites of gene amplification by modulation of gene expression and DNA methylation.

  Journal of cellular biochemistry 20071001

• Differentiation-promoting drugs up-regulate NKG2D ligand expression and enhance the susceptibility of acute myeloid leukemia cells to natural killer cell-mediated lysis.

  Leukemia research 20071001

• Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer.

  Molecular carcinogenesis 20071001

• Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells.

  Journal of cellular physiology 20071001

• Novel approach for detecting global epigenetic alterations associated with tumor cell aneuploidy.

  International journal of cancer 20071001

• Potential advantages of DNA methyltransferase 1 (DNMT1)-targeted inhibition for cancer therapy.

  Journal of molecular medicine (Berlin, Germany) 20071001

• Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.

  Blood 20071001

• Promoter methylation regulates estrogen receptor 2 in human endometrium and endometriosis.

  Biology of reproduction 20071001

• In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells. The role of 5-azacytidine.

  Interactive cardiovascular and thoracic surgery 20071001

• Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation.

  Molecular and cellular biology 20071001

• Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes.

  International journal of oncology 20071001

• Methylation and intratumoural heterogeneity of 14-3-3 sigma in oral cancer.

  Oncology reports 20071001

• Epigenetic alterations and cancer: new targets for therapy.

  IDrugs : the investigational drugs journal 20071001

• O6-methylguanine-DNA-methyltransferase promoter demethylation is involved in basic fibroblast growth factor induced resistance against temozolomide in human melanoma cells.

  Molecular cancer therapeutics 20071001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20071001

• Effects of 5-Aza-CdR on cell proliferation of breast cancer cell line MDA-MB-435S and expression of maspin gene.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20071001

• Decitabine in the treatment of myelodysplastic syndromes.

  Therapeutics and clinical risk management 20071001

• Frequent methylation-associated silencing of a candidate tumor-suppressor, CRABP1, in esophageal squamous-cell carcinoma.

  Oncogene 20070927

• Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma.

  Oncogene 20070920

• Gene induction and apoptosis in human hepatocellular carci-noma cells SMMC-7721 exposed to 5-aza-2'-deoxycytidine.

  Chinese medical journal 20070920

• Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma.

  The Prostate 20070915

• v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex.

  The Journal of biological chemistry 20070914

• Match unrelated bone marrow transplantation in a case of high risk myelodysplastic syndrome treated with azacitidine and concomitant 1alpha-25-dihydroxyvitamin D3, as differentiating agent.

  Leukemia research 20070901

• Clonogenic acute myelogenous leukemia cells are heterogeneous with regard to regulation of differentiation and effect of epigenetic pharmacological targeting.

  Leukemia research 20070901

• Analysis of the limitations of hepatitis B surface antigen expression in soybean cell suspension cultures.

  Plant cell reports 20070901

• Adverse effects of 5-aza-2'-deoxycytidine on spermatogenesis include reduced sperm function and selective inhibition of de novo DNA methylation.

  The Journal of pharmacology and experimental therapeutics 20070901

• CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine.

  Leukemia 20070901

• Dynamic DNA methylation reprogramming: active demethylation and immediate remethylation in the male pronucleus of bovine zygotes.

  Developmental dynamics : an official publication of the American Association of Anatomists 20070901

• Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901

• Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition.

  British journal of haematology 20070901

• Decitabine up-regulates S100A2 expression and synergizes with IFN-gamma to kill uveal melanoma cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070901

• The use of hypomethylating agents in the treatment of hematologic malignancies.

  Leukemia & lymphoma 20070901

• 5-Azacytidine induced methyltransferase-DNA adducts block DNA replication in vivo.

  Cancer research 20070901

• Transbuccal delivery of 5-aza-2 -deoxycytidine: effects of drug concentration, buffer solution, and bile salts on permeation.

  AAPS PharmSciTech 20070901

• The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model.

  British journal of cancer 20070820

• SGNE1/7B2 is epigenetically altered and transcriptionally downregulated in human medulloblastomas.

  Oncogene 20070816

• Characterization of acid-base properties of unstable drugs using a continuous-flow system with UV-vis spectrophotometric detection.

  Journal of pharmaceutical and biomedical analysis 20070815

• Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer.

  Cancer research 20070815

• Ornithine decarboxylase antizyme upregulates DNA-dependent protein kinase and enhances the nonhomologous end-joining repair of DNA double-strand breaks in human oral cancer cells.

  Biochemistry 20070807

• Frequent inactivation of SPARC by promoter hypermethylation in colon cancers.

  International journal of cancer 20070801

• Epigenetic silencing of the candidate tumor suppressor gene PROX1 in sporadic breast cancer.

  International journal of cancer 20070801

• Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells.

  International journal of cancer 20070801

• Trichostatin A, sodium butyrate, and 5-aza-2'-deoxycytidine alter the expression of glucocorticoid receptor alpha and beta isoforms in Hut-78 T- and Raji B-lymphoma cell lines.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070801

• Transcriptional activation of steroidogenic factor-1 by hypomethylation of the 5' CpG island in endometriosis.

  The Journal of clinical endocrinology and metabolism 20070801

• Preferential cytogenetic response to continuous intravenous low-dose decitabine (DAC) administration in myelodysplastic syndrome with monosomy 7.

  Blood 20070801

• Decitabine dosage in myelodysplastic syndromes.

  Blood 20070801

• Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070801

• The interferon-alpha responsive gene TMEM7 suppresses cell proliferation and is downregulated in human hepatocellular carcinoma.

  Cancer genetics and cytogenetics 20070801

• Decitabine and its role in the treatment of hematopoietic malignancies.

  Leukemia & lymphoma 20070801

• Monocytic skin nodules in chronic myelomonocytic leukemia: clinical response to decitabine therapy.

  Leukemia & lymphoma 20070801

• High expressions of neuronatin isoforms in favorable neuroblastoma.

  Journal of pediatric hematology/oncology 20070801

• Lenalidomide: a brief review of its therapeutic potential in myelodysplastic syndromes.

  Therapeutics and clinical risk management 20070801

• Short hairpin RNA causes the methylation of transforming growth factor-beta receptor II promoter and silencing of the target gene in rat hepatic stellate cells.

  Biochemical and biophysical research communications 20070727

• Epigenetic silencing of HSulf-1 in ovarian cancer:implications in chemoresistance.

  Oncogene 20070726

• [The role of secreted Wnt-antagonist genes hypermethylation in early detection of colorectal tumor].

  Zhonghua yi xue za zhi 20070724

• Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers.

  Oncogene 20070719

• Potential target antigens for immunotherapy in human pancreatic cancer.

  Cancer letters 20070718

• Epigenetic deregulation of multiple S100 gene family members by differential hypomethylation and hypermethylation events in medulloblastoma.

  British journal of cancer 20070716

• Silencing of tissue factor pathway inhibitor-2 gene in malignant melanomas.

  International journal of cancer 20070715

• Effect of cytarabine and decitabine in combination in human leukemic cell lines.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070715

• Hypermethylation of Ron proximal promoter associates with lack of full-length Ron and transcription of oncogenic short-Ron from an internal promoter.

  Oncogene 20070705

• Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.

  Breast cancer research and treatment 20070701

• Epigenetic regulation of human alpha1d-adrenergic receptor gene expression: a role for DNA methylation in Sp1-dependent regulation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070701

• The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.

  Laboratory investigation; a journal of technical methods and pathology 20070701

• Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors.

  Genes, chromosomes & cancer 20070701

• Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters.

  Molecular and cellular biology 20070701

• Endosperm-specific hypomethylation, and meiotic inheritance and variation of DNA methylation level and pattern in sorghum (Sorghum bicolor L.) inter-strain hybrids.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20070701

• Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma.

  Cancer 20070701

• Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides.

  Cancer research 20070701

• Effects of chromatin-modifying agents on CD34+ cells from patients with idiopathic myelofibrosis.

  Cancer research 20070701

• Epigenetic inactivation of E-cadherin by promoter hypermethylation in oral carcinoma cells.

  Odontology 20070701

• Use of hypomethylating agents in myelodysplastic syndromes.

  Clinical advances in hematology & oncology : H&O 20070701

• Effects of 5-aza-2'-deoxycytidine on the gene expression profile during embryogenesis of the Ascidian ciona intestinalis: a microarray analysis.

  Zoological science 20070701

• [Relationship between RAR-beta gene expression defect and its methylation].

  Zhonghua fu chan ke za zhi 20070701

• Expression of GAGE family proteins in malignant melanoma.

  Cancer letters 20070628

• Differential expression of galectins in normal, benign and malignant prostate epithelial cells: silencing of galectin-3 expression in prostate cancer by its promoter methylation.

  Biochemical and biophysical research communications 20070622

• Downregulation and CpG island hypermethylation of NES1/hK10 gene in the pathogenesis of human gastric cancer.

  Cancer letters 20070618

• DNA demethylation reactivation of imprinted genes in cell lines from patients with Prader-Willi syndrome and a mouse model.

  American journal of medical genetics. Part A 20070615

• Epigenetic and functional analysis of IGFBP3 and IGFBPrP1 in cellular immortalization.

  Biochemical and biophysical research communications 20070608

• Comprehensive conformational analysis of the nucleoside analogue 2'-beta-deoxy-6-azacytidine by DFT and MP2 calculations.

  The journal of physical chemistry. B 20070607

• A selective activity of DNMTi decitabine on AML1ETO positive cells?

  Leukemia research 20070601

• Control of hematopoiesis and apoptosis in MDS: more than FLIPing the coin.

  Leukemia research 20070601

• DNA methylation regulates tissue-specific expression of Shank3.

  Journal of neurochemistry 20070601

• Overlapping roles of the methylated DNA-binding protein MBD1 and polycomb group proteins in transcriptional repression of HOXA genes and heterochromatin foci formation.

  The Journal of biological chemistry 20070601

• Transcriptional silencing of the TMS1/ASC tumour suppressor gene by an epigenetic mechanism in hepatocellular carcinoma cells.

  The Journal of pathology 20070601

• Functional up-regulation of human leukocyte antigen class I antigens expression by 5-aza-2'-deoxycytidine in cutaneous melanoma: immunotherapeutic implications.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070601

• Down-regulation of PU.1 by methylation of distal regulatory elements and the promoter is required for myeloma cell growth.

  Cancer research 20070601

• Epigenetic dysregulation of the death-associated protein kinase/p14/HDM2/p53/Apaf-1 apoptosis pathway in multiple myeloma.

  Journal of clinical pathology 20070601

• [Effect of adenomatous polyposis coli(APC) promoter methylation on gene transcription in lung cancer cell lines].

  Ai zheng = Aizheng = Chinese journal of cancer 20070601

• Selection for robustness in mutagenized RNA viruses.

  PLoS genetics 20070601

• 5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

  Molecular cancer therapeutics 20070601

• Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20070601

• DNA methyltransferases as targets for cancer therapy.

  Drugs of today (Barcelona, Spain : 1998) 20070601

• Re-expression of RASSF1A by 5-Aza-CdR induced demethylation of the promoter region in human biliary tract carcinoma cells.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20070601

• The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.

  Cancer biotherapy & radiopharmaceuticals 20070601

• In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer.

  British journal of cancer 20070521

• Trichostatin A and 5-aza-2'-deoxycytidine switch S1P from an inhibitor to a stimulator of motility through epigenetic regulation of S1P receptors.

  Cancer letters 20070518

• Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.

  Blood 20070515

• Genetic redundancy in human cervical carcinoma cells: identification of cells with 'normal' properties.

  International journal of cancer 20070515

• MAGE-A9 mRNA and protein expression in bladder cancer.

  International journal of cancer 20070515

• Epigenetic combination therapy as a tumor-selective treatment approach for hepatocellular carcinoma.

  Cancer 20070515

• Tumor suppressor activity of CCAAT/enhancer binding protein alpha is epigenetically down-regulated in head and neck squamous cell carcinoma.

  Cancer research 20070515

• Acute myeloid leukemia and myelodysplastic syndromes in older patients.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070510

• Larger numbers of silenced genes in cancer cell lines with increased de novo methylation of scattered CpG sites.

  Cancer letters 20070508

• Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.

  Annals of surgical oncology 20070501

• The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.

  Blood 20070501

• Mechanism of in vivo sister-chromatid exchange induction by 5-azacytidine.

  Mutagenesis 20070501

• The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.

  FEMS microbiology letters 20070501

• Discovery of epigenetically silenced genes in acute myeloid leukemias.

  Leukemia 20070501

• Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression.

  The Journal of pathology 20070501

• Aberrant DNA methylation of the Src kinase Hck, but not of Lyn, in Philadelphia chromosome negative acute lymphocytic leukemia.

  Leukemia 20070501

• The incidence and impact of thrombocytopenia in myelodysplastic syndromes.

  Cancer 20070501

• Complete response of deep neutrophilic dermatosis associated with myelodysplastic syndrome to 5-azacytidine.

  The British journal of dermatology 20070501

• Down-regulation of IL-7Ralpha expression in human T cells via DNA methylation.

  Journal of immunology (Baltimore, Md. : 1950) 20070501

• Methylation of Ras association domain family protein 1, isoform A correlated with proliferation and drug resistance in hepatocellular carcinoma cell line SMMC-7721.

  Journal of gastroenterology and hepatology 20070501

• LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.

  Cancer research 20070501

• Tissue factor pathway inhibitor-2 as a frequently silenced tumor suppressor gene in hepatocellular carcinoma.

  Hepatology (Baltimore, Md.) 20070501

• Identification of epigenetically silenced genes in tumor endothelial cells.

  Cancer research 20070501

• Azacitidine pharmacokinetics in an adolescent patient with renal compromise.

  Journal of pediatric hematology/oncology 20070501

• Differential promoter methylation may be a key molecular mechanism in regulating BubR1 expression in cancer cells.

  Experimental & molecular medicine 20070430

• Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum.

  British journal of cancer 20070423

• Pharmacologic inhibition of epigenetic modifications, coupled with gene expression profiling, reveals novel targets of aberrant DNA methylation and histone deacetylation in lung cancer.

  Oncogene 20070419

• Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia.

  Blood 20070415

• Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential.

  Blood 20070415

• The use of histone deacetylase inhibitor FK228 and DNA hypomethylation agent 5-azacytidine in human bladder cancer therapy.

  International journal of cancer 20070415

• High-resolution analysis of 3p deletion in neuroblastoma and differential methylation of the SEMA3B tumor suppressor gene.

  Cancer genetics and cytogenetics 20070415

• Strategies for achieving transfusion independence in myelodysplastic syndromes.

  European journal of oncology nursing : the official journal of European Oncology Nursing Society 20070401

• Reversal of p15/INK4b hypermethylation in AML1/ETO-positive and -negative myeloid leukemia cell lines.

  Leukemia research 20070401

• Vitamin A and beta-carotene inhibitory effect during 1,2-dimethylhydrazine induced hepatocarcinogenesis potentiated by 5-azacytidine.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401

• Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.

  Annals of surgical oncology 20070401

• Differentiation-specific association of HP1alpha and HP1beta with chromocentres is correlated with clustering of TIF1beta at these sites.

  Histochemistry and cell biology 20070401

• Real-time fluorescence tracking of dynamic transgene variegation in stem cells.

  Molecular therapy : the journal of the American Society of Gene Therapy 20070401

• Epigenetic inactivation of chalcone synthase-A transgene transcription in petunia leads to a reversion of the post-transcriptional gene silencing phenotype.

  Plant & cell physiology 20070401

• Transcriptional reactivation of murine cytomegalovirus ie gene expression by 5-aza-2'-deoxycytidine and trichostatin A in latently infected cells despite lack of methylation of the major immediate-early promoter.

  The Journal of general virology 20070401

• Recent advances in myelodysplastic syndromes.

  Experimental hematology 20070401

• 5-aza-2'-deoxycytidine delays androgen-independent disease and improves survival in the transgenic adenocarcinoma of the mouse prostate mouse model of prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070401

• Claudin-7 is highly expressed in chromophobe renal cell carcinoma and renal oncocytoma.

  Journal of Korean medical science 20070401

• [Pluripotential differentiation of QY1 bone marrow mesenchymal stem cell line].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070401

• Promoter methylation of PARG1, a novel candidate tumor suppressor gene in mantle-cell lymphomas.

  Haematologica 20070401

• The comparative effects of gene modulators on thyroid-specific genes and radioiodine uptake.

  Cancer biotherapy & radiopharmaceuticals 20070401

• Current treatment options: impact of cytogenetics on the course of myelodysplasia.

  Current treatment options in oncology 20070401

• Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol.

  The Journal of biological chemistry 20070323

• Survival advantage with decitabine versus intensive chemotherapy in patients with higher risk myelodysplastic syndrome: comparison with historical experience.

  Cancer 20070315

• Covalent modification of DNA regulates memory formation.

  Neuron 20070315

• DNA methylation as a therapeutic target in cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070315

• 5-AZA-2'-deoxycytidine in cancer immunotherapy: a mouse to man story.

  Cancer research 20070315

• Lytic induction and apoptosis of Epstein-Barr virus-associated gastric cancer cell line with epigenetic modifiers and ganciclovir.

  Cancer letters 20070308

• Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.

  Pediatric blood & cancer 20070301

• Induction of complete remission in a patient with acute myeloid leukemia refractory to high-dose chemotherapy through treatment with 5-azacytidine.

  Leukemia research 20070301

• DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes.

  Molecular pharmacology 20070301

• Protein synthesis inhibitors, in synergy with 5-azacytidine, restore sodium/iodide symporter gene expression in human thyroid adenoma cell line, KAK-1, suggesting trans-active transcriptional repressor.

  The Journal of clinical endocrinology and metabolism 20070301

• Insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) has potential tumour-suppressive activity in human lung cancer.

  The Journal of pathology 20070301

• Phase II study of low-dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia.

  Cancer 20070301

• Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method.

  Nucleic acids research 20070301

• Promoter methylation status of the Cyclin D2 gene is associated with poor prognosis in human epithelial ovarian cancer.

  Cancer science 20070301

• The myelodysplastic syndromes.

  Expert opinion on biological therapy 20070301

• Myelodysplasia: the good, the fair and the ugly.

  Best practice & research. Clinical haematology 20070301

• Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.

  Genes to cells : devoted to molecular & cellular mechanisms 20070301

• Stress chaperones, mortalin, and pex19p mediate 5-aza-2' deoxycytidine-induced senescence of cancer cells by DNA methylation-independent pathway.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20070301

• Intravenous azacitidine for MDS.

  Clinical advances in hematology & oncology : H&O 20070301

• The role of CpG methylation in cell type-specific expression of the aquaporin-5 gene.

  Biochemical and biophysical research communications 20070223

• Transplantation of autologous adipose-derived stem cells ameliorates cardiac function in rabbits with myocardial infarction.

  Chinese medical journal 20070220

• Igf-2r expression regulated by epigenetic modification and the locus of gene imprinting disrupted in cloned cattle.

  Gene 20070215

• Activity of decitabine, a hypomethylating agent, in chronic myelomonocytic leukemia.

  Cancer 20070215

• A role for bone morphogenetic protein-4 in adipocyte development.

  Cell cycle (Georgetown, Tex.) 20070215

• Methylation status of the Ep-CAM promoter region in human breast cancer cell lines and breast cancer tissue.

  Cancer letters 20070208

• Successful treatment of relapsed AML after allogeneic stem cell transplantation with azacitidine.

  Leukemia research 20070201

• Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activator.

  Experimental and molecular pathology 20070201

• Plasticity of Ly49g expression is due to epigenetics.

  Molecular immunology 20070201

• Regulation of myofibroblast transdifferentiation by DNA methylation and MeCP2: implications for wound healing and fibrogenesis.

  Cell death and differentiation 20070201

• Regulation of Cdx2 expression by promoter methylation, and effects of Cdx2 transfection on morphology and gene expression of human esophageal epithelial cells.

  Carcinogenesis 20070201

• Decitabine--bedside to bench.

  Critical reviews in oncology/hematology 20070201

• Decitabine and vitamin D3 differentially affect hematopoietic transcription factors to induce monocytic differentiation.

  International journal of oncology 20070201

• Epigenetic control of nuclear architecture.

  Cellular and molecular life sciences : CMLS 20070201

• Downregulation of RECK by promoter methylation correlates with lymph node metastasis in non-small cell lung cancer.

  Cancer science 20070201

• Application of mesenchymal stem cell-derived cardiomyocytes as bio-pacemakers: current status and problems to be solved.

  Medical & biological engineering & computing 20070201

• Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene.

  Nucleic acids research 20070201

• Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin.

  Cancer research 20070201

• Effect of 6-azacytidine on the course of experimental adenoviral infection in newborn Syrian hamsters.

  Journal of chemotherapy (Florence, Italy) 20070201

• [Differentiation of QY1 bone marrow pluripotential mesenchymal stem cell line cells into cardiomyocytes and vascular endothelial cells in vitro].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070201

• Recent experience with decitabine in MDS.

  Clinical advances in hematology & oncology : H&O 20070201

• Downregulation of RUNX3 and TES by hypermethylation in glioblastoma.

  Oncogene 20070125

• Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome.

  Cancer 20070115

• 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation.

  Oncogene 20070104

• Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia.

  Blood 20070101

• Methylation status of a single CpG locus 3 bases upstream of TATA-box of receptor activator of nuclear factor-kappaB ligand (RANKL) gene promoter modulates cell- and tissue-specific RANKL expression and osteoclastogenesis.

  Molecular endocrinology (Baltimore, Md.) 20070101

• Inactivation of RASSF2A by promoter methylation correlates with lymph node metastasis in nasopharyngeal carcinoma.

  International journal of cancer 20070101

• Annexin-I as a potential target for green tea extract induced actin remodeling.

  International journal of cancer 20070101

• Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity.

  International journal of cancer 20070101

• High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array.

  Human genetics 20070101

• Efficacy of DNA hypomethylating capacities of 5-aza-2'-deoxycytidine and its alpha anomer.

  Pharmacological research 20070101

• Relationship of aberrant DNA hypermethylation of CHFR with sensitivity to taxanes in endometrial cancer.

  Oncology reports 20070101

• The role of decitabine in the treatment of myelodysplastic syndromes.

  Expert opinion on pharmacotherapy 20070101

• DNA methylation promotes Aurora-B-driven phosphorylation of histone H3 in chromosomal subdomains.

  Journal of cell science 20070101

• Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070101

• Growth of the protozoan parasite Entamoeba histolytica in 5-azacytidine has limited effects on parasite gene expression.

  BMC genomics 20070101

• Inhibition of histone deacetylation does not block resilencing of p16 after 5-aza-2'-deoxycytidine treatment.

  Cancer research 20070101

• Zebularine reactivates silenced E-cadherin but unlike 5-Azacytidine does not induce switching from latent to lytic Epstein-Barr virus infection in Burkitt's lymphoma Akata cells.

  Molecular cancer 20070101

• [Role of epigenetics in the carcinogenesis of head and neck carcinomas - possible new targeted therapy?].

  Laryngo- rhino- otologie 20070101

• Identification of candidate methylation-responsive genes in ovarian cancer.

  Molecular cancer 20070101

• Cord blood in regenerative medicine: do we need immune suppression?

  Journal of translational medicine 20070101

• [Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070101

• Risk-based management of myelodysplastic syndrome.

  Oncology (Williston Park, N.Y.) 20070101

• DAPK1 promoter hypermethylaiton in brain metastases and peripheral blood.

  Neoplasma 20070101

• Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis.

  BMC genomics 20070101

• The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study.

  Virology journal 20070101

• Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response.

  Virology journal 20070101

• Some facts and thoughts: p73 as a tumor suppressor gene in the network of tumor suppressors.

  Molecular cancer 20070101

• Lytic cycle switches of oncogenic human gammaherpesviruses.

  Advances in cancer research 20070101

• Human pluripotent embryonal carcinoma NTERA2 cl.D1 cells maintain their typical morphology in an angiomyogenic medium.

  Journal of negative results in biomedicine 20070101

• Simultaneously optimizing dose and schedule of a new cytotoxic agent.

  Clinical trials (London, England) 20070101

• DNA methyltransferase inhibitors for cancer therapy.

  Cancer journal (Sudbury, Mass.) 20070101

• Utilization of chromatin remodeling agents for lung cancer therapy.

  Cancer journal (Sudbury, Mass.) 20070101

• Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells.

  Anticancer research 20070101

• Stringent and reproducible tetracycline-regulated transgene expression by site-specific insertion at chromosomal loci with pre-characterised induction characteristics.

  BMC molecular biology 20070101

• Current status of lupus genetics.

  Arthritis research & therapy 20070101

• The impact of 5-azacytidine on placental weight, glycoprotein pattern and proliferating cell nuclear antigen expression in rat placenta.

  Placenta 20070101

• New drugs: paliperidone, dasatinib, and decitabine.

  Journal of the American Pharmacists Association : JAPhA 20070101

• Diverse histone modifications on histone 3 lysine 9 and their relation to DNA methylation in specifying gene silencing.

  BMC genomics 20070101

• Genome position and gene amplification.

  Genome biology 20070101

• Trichostatin A effects on gene expression in the protozoan parasite Entamoeba histolytica.

  BMC genomics 20070101

• Transcriptional and epigenetic regulation of the integrin collagen receptor locus ITGA1-PELO-ITGA2.

  Biochimica et biophysica acta 20070101

• The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells.

  Genome biology 20070101

• Locus-specific ribosomal RNA gene silencing in nucleolar dominance.

  PloS one 20070101

• Decitabine and sickle cell disease: molecular therapy for a molecular disease.

  Pediatric hematology and oncology 20070101

• An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated.

  BMC molecular biology 20070101

• The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo.

  Journal of translational medicine 20070101

• DNA methylation state is preserved in the sperm-derived pronucleus of the pig zygote.

  The International journal of developmental biology 20070101

• Modulation of HLA-G expression.

  Neoplasma 20070101

• Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies.

  BMC evolutionary biology 20070101

• Somaclonal variation at the nucleotide sequence level in rice (Oryza sativa L.) as revealed by RAPD and ISSR markers, and by pairwise sequence analysis.

  Journal of applied genetics 20070101

• Endometrial regenerative cells: a novel stem cell population.

  Journal of translational medicine 20070101

• Chromatin, gene silencing and HIV latency.

  Genome biology 20070101

• Candidate tumor suppressor gene SLC5A8 is frequently down-regulated by promoter hypermethylation in prostate tumor.

  Cancer detection and prevention 20070101

• Epigenetic regulation of RhoB loss of expression in lung cancer.

  BMC cancer 20070101

• The effects of nucleoside analogues on promoter methylation of selected tumor suppressor genes in MCF-7 and MDA-MB-231 breast cancer cell lines.

  Nucleosides, nucleotides & nucleic acids 20070101

• Plasmid-based genetic modification of human bone marrow-derived stromal cells: analysis of cell survival and transgene expression after transplantation in rat spinal cord.

  BMC biotechnology 20070101

• Rice transposable elements are characterized by various methylation environments in the genome.

  BMC genomics 20070101

• Relationships between transcription, silver staining, and chromatin organization of nucleolar organizers in Secale cereale.

  Protoplasma 20070101

• A role for DNA methylation in regulating the growth suppressor PMEPA1 gene in prostate cancer.

  Epigenetics 20070101

• A sequential treatment of depsipeptide followed by 5-azacytidine enhances Gadd45beta expression in hepatocellular carcinoma cells.

  Anticancer research 20070101

• Targeted brain tumor treatment-current perspectives.

  Drug target insights 20070101

• Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.

  British journal of cancer 20061218

• SPAN-XB core promoter sequence is regulated in myeloma cells by specific CpG dinucleotides associated with the MeCP2 protein.

  International journal of cancer 20061215

• 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer).

  Biochemical and biophysical research communications 20061215

• RIZ1 is epigenetically inactivated by promoter hypermethylation in thyroid carcinoma.

  Cancer 20061215

• Low-dose decitabine and high-risk MDS.

  Blood 20061215

• Aberrant DNA demethylation in promoter region and aberrant expression of mRNA of PAX4 gene in hematologic malignancies.

  Leukemia research 20061201

• Downregulation of circadian clock genes in chronic myeloid leukemia: alternative methylation pattern of hPER3.

  Cancer science 20061201

• Inhibitors of DNA methylation and histone deacetylation independently relieve AML1/ETO-mediated lysozyme repression.

  Journal of leukocyte biology 20061201

• DNA methylation-dependent silencing of CST6 in human breast cancer cell lines.

  Laboratory investigation; a journal of technical methods and pathology 20061201

• Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.

  Neuroscience research 20061201

• Cytotoxic activity of gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukemia correlates with the expression of protein kinase Syk.

  Leukemia 20061201

• Chemotherapeutic agents for colorectal cancer with a defective mismatch repair system: the state of the art.

  Cancer treatment reviews 20061201

• Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

  Gastroenterology 20061201

• Epigenetic silencing of novel tumor suppressors in malignant melanoma.

  Cancer research 20061201

• 5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells.

  Cell research 20061201

• A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.

  PLoS medicine 20061201

• Association of DNA methylation and epigenetic inactivation of RASSF1A and beta-catenin with metastasis in small bowel carcinoid tumors.

  Endocrine 20061201

• [Expression of ER alpha in chemically induced MDA-MB-435 cells and its responsiveness to endocrine].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201

• [Demethylation of estrogen receptor gene and its re-expression in estrogen receptor-negative breast].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20061201

• Editorial foreword.

  Therapeutics and clinical risk management 20061201

• Azacytidine (Vidaza(R)) in the treatment of myelodysplastic syndromes.

  Therapeutics and clinical risk management 20061201

• Identification of novel genes associated with astrocytoma progression using suppression subtractive hybridization and real-time reverse transcription-polymerase chain reaction.

  International journal of cancer 20061115

• Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.

  Blood 20061115

• The expression of metastasis suppressor MIM/MTSS1 is regulated by DNA methylation.

  International journal of cancer 20061115

• Reprimo methylation is a potential biomarker of Barrett's-Associated esophageal neoplastic progression.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061115

• Decitabine (Dacogen) for myelodysplastic syndromes.

  The Medical letter on drugs and therapeutics 20061106

• Effect of histone deacetylase inhibitor LAQ824 on antineoplastic action of 5-Aza-2'-deoxycytidine (decitabine) on human breast carcinoma cells.

  Cancer chemotherapy and pharmacology 20061101

• Further studies on aberrant gene expression associated with arsenic-induced malignant transformation in rat liver TRL1215 cells.

  Toxicology and applied pharmacology 20061101

• Epigenetic regulation of human trophoblastic cell migration and invasion.

  Endocrinology 20061101

• Aberrant promoter methylation of the ABCG2 gene in renal carcinoma.

  Molecular and cellular biology 20061101

• Diagnostic utility of aberrant methylation of tissue factor pathway inhibitor 2 in pure pancreatic juice for pancreatic carcinoma.

  Cancer science 20061101

• Hypomethylation of the protein gene product 9.5 promoter region in gallbladder cancer and its relationship with clinicopathological features.

  Cancer science 20061101

• Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.

  Journal of molecular medicine (Berlin, Germany) 20061101

• Epigenetic allele silencing unveils recessive RYR1 mutations in core myopathies.

  American journal of human genetics 20061101

• Global DNA and p53 region-specific hypomethylation in human colonic cells is induced by folate depletion and reversed by folate supplementation.

  The Journal of nutrition 20061101

• Human immunodeficiency virus impairs reverse cholesterol transport from macrophages.

  PLoS biology 20061101

• Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer.

  Cancer research 20061101

• Interleukin-6 contributes to growth in cholangiocarcinoma cells by aberrant promoter methylation and gene expression.

  Cancer research 20061101

• Decitabine.

  Nature reviews. Drug discovery 20061101

• [Effect of spleen tyrosine kinase expression re-activation by inhibition of DNA methylation on oncogenesis growth of gastric cancer].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20061101

• Repair process of fetal brain after 5-azacytidine-induced damage.

  The European journal of neuroscience 20061101

• Targeting the epigenome for the treatment of thoracic malignancies.

  Thoracic surgery clinics 20061101

• Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes.

  Annals of the New York Academy of Sciences 20061101

• Epigenetic inactivation of EGFR by CpG island hypermethylation in cancer.

  Cancer biology & therapy 20061101

• Methylation of the mouse DIx5 and Osx gene promoters regulates cell type-specific gene expression.

  Molecules and cells 20061031

• [Expression of S100A2 in secondarily radioresistant pancreatic cancer cells and significance thereof].

  Zhonghua yi xue za zhi 20061031

• Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation.

  Cancer letters 20061028

• Epigenetic cancer therapy makes headway.

  Journal of the National Cancer Institute 20061018

• MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer.

  International journal of cancer 20061015

• DNA mismatch repair as an effector for promoting phorbol ester-induced apoptotic DNA damage and cell killing: implications in tumor promotion.

  International journal of cancer 20061015

• Treatment of acute myelogenous leukemia with outpatient azacitidine.

  Cancer 20061015

• Reaction of hydroxyl radicals with azacytosines: a pulse radiolysis and theoretical study.

  The journal of physical chemistry. A 20061012

• Effect of aging on the pluripotential capacity of human CD105+ mesenchymal stem cells.

  European journal of heart failure 20061001

• Analysis of genes upregulated by the demethylating agent 5-aza-2'-deoxycytidine in gastric cancer cell lines.

  International journal of cancer 20061001

• Differentially methylated alleles in a distinct region of the human interleukin-1alpha promoter are associated with allele-specific expression of IL-1alpha in CD4+ T cells.

  Blood 20061001

• Epigenetic regulation of the rice retrotransposon Tos17.

  Molecular genetics and genomics : MGG 20061001

• PML-RARalpha and AML1-ETO translocations are rarely associated with methylation of the RARbeta2 promoter.

  Annals of hematology 20061001

• Epigenetic regulation of maspin expression in the human placenta.

  Molecular human reproduction 20061001

• Genetic analysis and epigenetic silencing of At4CL1 and At4CL2 expression in transgenic Arabidopsis.

  Biotechnology journal 20061001

• An EBF3-mediated transcriptional program that induces cell cycle arrest and apoptosis.

  Cancer research 20061001

• Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20061001

• Improved DNA methylation analysis via enrichment of demethylated cells expressing an X-inactivated transgene.

  BioTechniques 20061001

• DNA hypermethylation of myeloid cells, a novel therapeutic target in MDS and AML.

  Current pharmaceutical biotechnology 20061001

• Proteomic profiling of rat bone marrow mesenchymal stem cells induced by 5-azacytidine.

  Stem cells and development 20061001

• [SHP-1 gene's methylation status of Daudi lymphoma cell and the demethylation effect of 5-aza-2'-deoxycytidine].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20061001

• Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues.

  World journal of gastroenterology 20060921

• Silencing of the UCHL1 gene in human colorectal and ovarian cancers.

  International journal of cancer 20060915

• B29 gene silencing in pituitary cells is regulated by its 3' enhancer.

  Journal of molecular biology 20060915

• High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma.

  Journal of clinical pathology 20060901

• DNA methylation levels in porcine fetal fibroblasts induced by an inhibitor of methylation, 5-azacytidine.

  Cell and tissue research 20060901

• Regulation of the expression of human organic anion transporter 3 by hepatocyte nuclear factor 1alpha/beta and DNA methylation.

  Molecular pharmacology 20060901

• Synergic antiproliferative effect of DNA methyltransferase inhibitor in combination with anticancer drugs in gastric carcinoma.

  Cancer science 20060901

• Regulation of DNA methylation on the expression of the FHIT gene contributes to cervical carcinoma cell tumorigenesis.

  Oncology reports 20060901

• Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma.

  Leukemia 20060901

• Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells.

  Experimental hematology 20060901

• Enhancement of sodium/iodide symporter expression in thyroid and breast cancer.

  Endocrine-related cancer 20060901

• Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20060901

• The genomics of new drugs in sickle cell disease.

  Pharmacogenomics 20060901

• Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia.

  International journal of nanomedicine 20060901

• 5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8.

  Oncogene 20060824

• Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060820

• Oncogenic HRAS suppresses clusterin expression through promoter hypermethylation.

  Oncogene 20060810

• Overcoming resistance to interferon-induced apoptosis of renal carcinoma and melanoma cells by DNA demethylation.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060810

• Localized methylation in the key regulator gene endothelin-1 is associated with cell type-specific transcriptional silencing.

  FEBS letters 20060807

• Trisomy 19 as the sole chromosomal abnormality in proliferative chronic myelomonocytic leukemia.

  Leukemia research 20060801

• p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.

  Journal of cellular biochemistry 20060801

• Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration.

  Stem cells (Dayton, Ohio) 20060801

• Epigenetic inactivation of the dioxin-responsive cytochrome P4501A1 gene in human prostate cancer.

  Cancer research 20060801

• Epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma.

  Cancer research 20060801

• Phase I trial of sequential low-dose 5-aza-2'-deoxycytidine plus high-dose intravenous bolus interleukin-2 in patients with melanoma or renal cell carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060801

• Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer.

  Oncogene 20060706

• The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.

  Human reproduction (Oxford, England) 20060701

• LUMA (LUminometric Methylation Assay)--a high throughput method to the analysis of genomic DNA methylation.

  Experimental cell research 20060701

• Second complete remission in an elderly patient with acute myeloid leukemia retreated with decitabine.

  American journal of hematology 20060701

• A role for DNA hypomethylation and histone acetylation in maintaining allele-specific expression of mouse NKG2A in developing and mature NK cells.

  Journal of immunology (Baltimore, Md. : 1950) 20060701

• Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts.

  Arthritis and rheumatism 20060701

• RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer.

  Cancer research 20060701

• Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma.

  Cancer research 20060701

• Estrogen receptor-alpha methylation predicts melanoma progression.

  Cancer research 20060701

• Methylation of neutral endopeptidase 24.11 promoter in rat hepatocellular carcinoma.

  Cancer science 20060701

• [Effect of the epimutagen 5-azacytidine on the structure of floral-stalk metameres in sugar beet (Beta vulgaris L)].

  Genetika 20060701

• Bone marrow cells for cardiac regeneration and repair: current status and issues.

  Expert review of cardiovascular therapy 20060701

• Managing patients with low-risk MDS.

  Clinical advances in hematology & oncology : H&O 20060701

• Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancer.

  International journal of cancer 20060615

• Mouse follicular and marginal zone B cells show differential expression of Dnmt3a and sensitivity to 5'-azacytidine.

  Immunology letters 20060615

• Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms.

  Cancer research 20060615

• Restoration of tamoxifen sensitivity in estrogen receptor-negative breast cancer cells: tamoxifen-bound reactivated ER recruits distinctive corepressor complexes.

  Cancer research 20060615

• Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity.

  Biochemical and biophysical research communications 20060609

• GnT-V expression and metastatic phenotypes in macrophage-melanoma fusion hybrids is down-regulated by 5-Aza-dC: evidence for methylation sensitive, extragenic regulation of GnT-V transcription.

  Gene 20060607

• Sequential gene expression changes in cancer cell lines after treatment with the demethylation agent 5-Aza-2'-deoxycytidine.

  Cancer 20060601

• Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060601

• Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation.

  Alcoholism, clinical and experimental research 20060601

• Specific activation of microRNA-127 with downregulation of the proto-oncogene BCL6 by chromatin-modifying drugs in human cancer cells.

  Cancer cell 20060601

• Multiple mechanisms underlie the aberrant expression of the human kallikrein 6 gene in breast cancer.

  Biological chemistry 20060601

• The epigenetic basis for the aberrant expression of kallikreins in human cancers.

  Biological chemistry 20060601

• Targeted reduction of the DNA methylation level with 5-azacytidine promotes excision of the medaka fish Tol2 transposable element.

  Genetical research 20060601

• [Disfigurement of p16INK4A gene expression in development of ovarian cancer and the mechanism].

  Zhonghua fu chan ke za zhi 20060601

• Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression?

  Virology 20060525

• Effects of endothelin-1 on differentiation of cardiac myocyte induced from rabbit bone marrow stromal cells.

  Chinese medical journal 20060520

• Alterations of the Wnt signaling pathway during the neoplastic progression of Barrett's esophagus.

  Oncogene 20060518

• Excess methionine suppresses the methylation cycle and inhibits neural tube closure in mouse embryos.

  FEBS letters 20060515

• Identification of novel target genes by an epigenetic reactivation screen of renal cancer.

  Cancer research 20060515

• DNA methylation changes after 5-aza-2'-deoxycytidine therapy in patients with leukemia.

  Cancer research 20060515

• Regulation of high molecular weight-melanoma associated antigen (HMW-MAA) gene expression by promoter DNA methylation in human melanoma cells.

  Oncogene 20060511

• Lactate dehydrogenase-B is silenced by promoter hypermethylation in human prostate cancer.

  Oncogene 20060511

• Cell cycle progression is required for nuclear migration of neural progenitor cells.

  Brain research 20060509

• The dioxin receptor is silenced by promoter hypermethylation in human acute lymphoblastic leukemia through inhibition of Sp1 binding.

  Carcinogenesis 20060501

• Preferential methylation of Wnt inhibitory factor-1 in acute promyelocytic leukemia: an independent poor prognostic factor.

  Leukemia 20060501

• Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells.

  Journal of hepatology 20060501

• Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer.

  Oncology reports 20060501

• Abnormal activation of the synuclein-gamma gene in hepatocellular carcinomas by epigenetic alteration.

  International journal of oncology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease.

  American journal of human genetics 20060501

• Nickel ions increase histone H3 lysine 9 dimethylation and induce transgene silencing.

  Molecular and cellular biology 20060501

• Epigenetic inactivation of Betaig-h3 gene in human cancer cells.

  Cancer research 20060501

• Promoter demethylation and histone acetylation mediate gene expression of MAGE-A1, -A2, -A3, and -A12 in human cancer cells.

  Molecular cancer research : MCR 20060501

• [Transcription regulation of 5-Aza-2'-deoxycytidine on maspin gene demethylation in RKO human colorectal cell line].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20060501

• New strategies in chronic myeloid leukemia.

  International journal of hematology 20060501

• [Further improving the standard of treatment for chronic myeloid leukemia].

  Zhonghua nei ke za zhi 20060501

• Review: recent clinical trials in epigenetic therapy.

  Reviews on recent clinical trials 20060501

• Epigenetics as a mechanism driving polygenic clinical drug resistance.

  British journal of cancer 20060424

• Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b.

  Oncogene 20060420

• CpG methylation suppresses transcriptional activity of human syncytin-1 in non-placental tissues.

  Experimental cell research 20060415

• Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study.

  Cancer 20060415

• Drug therapy for myelodysplastic syndrome: building evidence for action.

  Cancer 20060415

• Superiority of prolonged low-dose azanucleoside administration? Results of 5-aza-2'-deoxycytidine retreatment in high-risk myelodysplasia patients.

  Cancer 20060415

• Loss of interleukin-2-dependency in HTLV-I-infected T cells on gene silencing of thioredoxin-binding protein-2.

  Oncogene 20060406

• Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications.

  Journal of cellular physiology 20060401

• Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

  Cell death and differentiation 20060401

• Promoter hypomethylation of Toll-like receptor-2 gene is associated with increased proinflammatory response toward bacterial peptidoglycan in cystic fibrosis bronchial epithelial cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401

• Pathophysiologically based drug treatment of sickle cell disease.

  Trends in pharmacological sciences 20060401

• Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells.

  Journal of immunology (Baltimore, Md. : 1950) 20060401

• A single nucleotide polymorphism chip-based method for combined genetic and epigenetic profiling: validation in decitabine therapy and tumor/normal comparisons.

  Cancer research 20060401

• Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.

  Cancer research 20060401

• PGP9.5 methylation in diffuse-type gastric cancer.

  Cancer research 20060401

• Gene promoter hypermethylation in mouse lung tumors.

  Molecular cancer research : MCR 20060401

• Altered nuclear receptor corepressor expression attenuates vitamin D receptor signaling in breast cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060401

• Enhanced differentiation of human embryonic stem cells into cardiomyocytes by combining hanging drop culture and 5-azacytidine treatment.

  Differentiation; research in biological diversity 20060401

• Myogenesis in hemopoietic tissue mesenchymal stem cell culture.

  Bulletin of experimental biology and medicine 20060401

• [Myelodysplastic syndromes--new treatment options].

  Medizinische Klinik (Munich, Germany : 1983) 20060322

• SPAN-Xb expression in myeloma cells is dependent on promoter hypomethylation and can be upregulated pharmacologically.

  International journal of cancer 20060315

• Epigenetic processes play a major role in B-cell-specific gene silencing in classical Hodgkin lymphoma.

  Blood 20060315

• Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.

  Journal of the National Cancer Institute 20060315

• Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060315

• Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1.

  Biochemical and biophysical research communications 20060310

• Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines.

  Biochemical and biophysical research communications 20060310

• Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer.

  Biochemical and biophysical research communications 20060310

• Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing.

  Biotechnology and bioengineering 20060305

• Treatment of myelodysplastic syndrome with a DNA methyltransferase inhibitor: lack of evidence for induction of chromosomal instability.

  Leukemia research 20060301

• Multi-gene epigenetic silencing of tumor suppressor genes in T-cell lymphoma cells; delayed expression of the p16 protein upon reversal of the silencing.

  Leukemia research 20060301

• Molecular inhibition of histone deacetylation results in major enhancement of the production of IL-1beta in response to LPS.

  American journal of physiology. Endocrinology and metabolism 20060301

• RAS-mediated epigenetic inactivation of OPCML in oncogenic transformation of human ovarian surface epithelial cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer.

  Cancer biology & therapy 20060301

• Promoter hypermethylation of FANCF plays an important role in the occurrence of ovarian cancer through disrupting Fanconi anemia-BRCA pathway.

  Cancer biology & therapy 20060301

• Cell cycle and cell death regulation of neural progenitor cells in the 5-azacytidine (5AzC)-treated developing fetal brain.

  Experimental neurology 20060301

• A novel terminal differentiation model of human articular chondrocytes in three-dimensional cultures mimicking chondrocytic changes in osteoarthritis.

  Cell biology international 20060301

• Epigenetics: the science of change.

  Environmental health perspectives 20060301

• Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region.

  The American journal of pathology 20060301

• Functional diversity of DNA methyltransferase inhibitors in human cancer cell lines.

  Cancer research 20060301

• Effect of methylation-associated silencing of the death-associated protein kinase gene on nasopharyngeal carcinoma.

  Anti-cancer drugs 20060301

• Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060301

• Effect of 5-aza-2'-deoxycytidine (Dacogen) on covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin promoters in Papio anubis.

  Experimental hematology 20060301

• Meiotically stable natural epialleles of Sadhu, a novel Arabidopsis retroposon.

  PLoS genetics 20060301

• Epigenetic repression of RASSF1A but not CASP8 in supratentorial PNET (sPNET) and atypical teratoid/rhabdoid tumors (AT/RT) of childhood.

  Oncogene 20060216

• Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation.

  Oncogene 20060216

• PDLIM4 repression by hypermethylation as a potential biomarker for prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060215

• In vitro cardiomyogenic potential of human umbilical vein-derived mesenchymal stem cells.

  Biochemical and biophysical research communications 20060210

• Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.

  Oncogene 20060209

• Cytogenetic and expression profiles associated with transformation to androgen-resistant prostate cancer.

  The Prostate 20060201

• Pilot study of combination transcriptional modulation therapy with sodium phenylbutyrate and 5-azacytidine in patients with acute myeloid leukemia or myelodysplastic syndrome.

  Leukemia 20060201

• Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.

  International journal of oncology 20060201

• A novel mechanism for acquired cisplatin-resistance: suppressed translation of death-associated protein kinase mRNA is insensitive to 5-aza-2'-deoxycitidine and trichostatin in cisplatin-resistant cervical squamous cancer cells.

  International journal of oncology 20060201

• Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis.

  Journal of the National Cancer Institute 20060201

• Expansion of human umbilical cord blood SCID-repopulating cells using chromatin-modifying agents.

  Experimental hematology 20060201

• Inhibition of DNA methylation increases follistatin expression and secretion in the human adrenocortical cell line NCI-H295R.

  The Journal of endocrinology 20060201

• Aberrant methylation of the eyes absent 4 gene in ulcerative colitis-associated dysplasia.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201

• The hematologic response to anti-apoptotic cytokine therapy: results of pentoxifylline, ciprofloxacin, and dexamethasone treatment for patients with myelodysplastic syndrome.

  Journal of Korean medical science 20060201

• Angiostatic activity of DNA methyltransferase inhibitors.

  Molecular cancer therapeutics 20060201

• Differential transcription of ovine herpesvirus 2 genes in lymphocytes from reservoir and susceptible species.

  Virus genes 20060201

• Characterisation of the GRAF gene promoter and its methylation in patients with acute myeloid leukaemia and myelodysplastic syndrome.

  British journal of cancer 20060130

• Epigenetics provides a new generation of oncogenes and tumour-suppressor genes.

  British journal of cancer 20060130

• CpG island methylation and expression of the secreted frizzled-related protein gene family in chronic lymphocytic leukemia.

  Cancer research 20060115

• De novo induction of a cancer/testis antigen by 5-aza-2'-deoxycytidine augments adoptive immunotherapy in a murine tumor model.

  Cancer research 20060115

• Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060115

• Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability.

  Oncogene 20060105

• 5-Aza-2'-deoxycytidine (decitabine) can relieve p21WAF1 repression in human acute myeloid leukemia by a mechanism involving release of histone deacetylase 1 (HDAC1) without requiring p21WAF1 promoter demethylation.

  Leukemia research 20060101

• Epigenetic regulation of lentiviral transgene vectors in a large animal model.

  Molecular therapy : the journal of the American Society of Gene Therapy 20060101

• Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060101

• Effects of 5-aza-2'-deoxycytidine on proliferation, differentiation and p15/INK4b regulation of human hematopoietic progenitor cells.

  Leukemia 20060101

• Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data.

  Anti-cancer drugs 20060101

• Promoter methylation reduces C/EBPdelta (CEBPD) gene expression in the SUM-52PE human breast cancer cell line and in primary breast tumors.

  Breast cancer research and treatment 20060101

• Aberrant promoter methylation of EDNRB in lung cancer in Taiwan.

  Oncology reports 20060101

• Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2'-deoxycytidine treatment and oligonucleotide microarray.

  Cancer science 20060101

• An active DNA transposon nDart causing leaf variegation and mutable dwarfism and its related elements in rice.

  The Plant journal : for cell and molecular biology 20060101

• Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer.

  Cancer research 20060101

• A pharmacodynamic study of 5-azacytidine in the P39 cell line.

  Experimental hematology 20060101

• Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapy.

  Breast cancer research : BCR 20060101

• Current therapy of sickle cell disease.

  Haematologica 20060101

• Discovery of novel methylation biomarkers in cervical carcinoma by global demethylation and microarray analysis.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060101

• Epigenetics and airways disease.

  Respiratory research 20060101

• Hydralazine target: from blood vessels to the epigenome.

  Journal of translational medicine 20060101

• Epigenetic regulation: DNA confers identity but is not enough to maintain it.

  Genome biology 20060101

• Myelodysplasia: when to treat and how.

  Best practice & research. Clinical haematology 20060101

• Characterization of decomposition products and preclinical and low dose clinical pharmacokinetics of decitabine (5-aza-2'-deoxycytidine) by a new liquid chromatography/tandem mass spectrometry quantification method.

  Rapid communications in mass spectrometry : RCM 20060101

• Effect of 5-azacytidine on the protein expression of porcine bone marrow mesenchymal stem cells in vitro.

  Genomics, proteomics & bioinformatics 20060101

• Immunodeficiency, centromeric region instability, facial anomalies syndrome (ICF).

  Orphanet journal of rare diseases 20060101

• Decitabine: in myelodysplastic syndromes.

  Drugs 20060101

• Decitabine in myelodysplastic syndromes: viewpoints.

  Drugs 20060101

• Slow, stochastic transgene repression with properties of a timer.

  Genome biology 20060101

• The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers.

  Molecular cancer 20060101

• Effects of autologous bone marrow stem cell transplantation on beta-adrenoceptor density and electrical activation pattern in a rabbit model of non-ischemic heart failure.

  Journal of cardiothoracic surgery 20060101

• Clinical evaluation of E-cadherin expression and its regulation mechanism in epithelial ovarian cancer.

  Clinical & experimental metastasis 20060101

• Methylation mediated silencing of TMS1/ASC gene in prostate cancer.

  Molecular cancer 20060101

• Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation.

  BMC genomics 20060101

• The potential regulation of L1 mobility by RNA interference.

  Journal of biomedicine & biotechnology 20060101

• Global DNA hypermethylation-associated cancer chemotherapy resistance and its reversion with the demethylating agent hydralazine.

  Journal of translational medicine 20060101

• MDS: navigating the complex course.

  ONS news 20060101

• Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.

  Molecular neurodegeneration 20060101

• The impact of iron overload and its treatment on quality of life: results from a literature review.

  Health and quality of life outcomes 20060101

• Inhibitors of histone deacetylases and DNA methyltransferases alter imprinted gene regulation in embryonic stem cells.

  Cloning and stem cells 20060101

• Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

  Molecular cancer 20060101

• 5' long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals.

  Retrovirology 20060101

• Alteration of DNA methylation status in K562 and MCF-7 cancer cell lines by nucleoside analogues.

  Nucleosides, nucleotides & nucleic acids 20060101

• Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells.

  Reproductive biology and endocrinology : RB&E 20060101

• Induction of fetal hemoglobin in the treatment of sickle cell disease.

  Hematology. American Society of Hematology. Education Program 20060101

• Clinical issues in the management of patients with myelodysplasia.

  Hematology. American Society of Hematology. Education Program 20060101

• Can 5-azacytidine convert the adult stem cells into cardiomyocytes? A brief overview.

  Archives of physiology and biochemistry 20060101

• A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer.

  PloS one 20060101

• New treatment for rare bone marrow condition.

  FDA consumer 20060101

• [Effect of 5-azacitidine on flower stalk branching in sugar beet (Beta vulgaris L.)].

  TSitologiia i genetika 20060101

• Methylation status of genes upregulated by demethylating agent 5-aza-2'-deoxycytidine in hepatocellular carcinoma.

  Oncology 20060101

• Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.

  Oncology research 20060101

• The synergistic effect of 5-aza-2'-deoxycytidine and 5-fluorouracil on drug-resistant tumors.

  Oncology 20060101

• 5-Aza-2'-deoxycytidine induces retinoic acid receptor-beta(2) demethylation and growth inhibition in esophageal squamous carcinoma cells.

  Cancer letters 20051218

• Inhibition of DNA methylation sensitizes glioblastoma for tumor necrosis factor-related apoptosis-inducing ligand-mediated destruction.

  Cancer research 20051215

• Alkaline induces metallothionein gene expression and potentiates cell proliferation in Chinese hamster ovary cells.

  Journal of cellular physiology 20051201

• Histone modification in the TGFbetaRII gene promoter and its significance for responsiveness to HDAC inhibitor in lung cancer cell lines.

  Molecular carcinogenesis 20051201

• Decitabine activates specific caspases downstream of p73 in myeloid leukemia.

  Annals of hematology 20051201

• An epigenetic approach to the treatment of advanced MDS; the experience with the DNA demethylating agent 5-aza-2'-deoxycytidine (decitabine) in 177 patients.

  Annals of hematology 20051201

• Decitabine: a historical review of the development of an epigenetic drug.

  Annals of hematology 20051201

• Butyrates and decitabine cooperate to induce histone acetylation and granulocytic maturation of t(8;21) acute myeloid leukemia blasts.

  Annals of hematology 20051201

• Clinical experience with decitabine in North American patients with myelodysplastic syndrome.

  Annals of hematology 20051201

• In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies.

  Annals of hematology 20051201

• Quantification of outpatient management and hospitalization of patients with high-risk myelodysplastic syndrome treated with low-dose decitabine.

  Annals of hematology 20051201

• The hematopathological basis for studying effects of the demethylating agent 5-aza-2'-deoxycytidine (decitabine) in myelodysplasia.

  Annals of hematology 20051201

• 5-Azacytidine decreases fragmentation of nuclear DNA and pigment formation in first leaf cells of barley seedlings.

  Cell biology international 20051201

• BRCA1 promoter methylation in sporadic breast cancer is associated with reduced BRCA1 copy number and chromosome 17 aneusomy.

  Cancer research 20051201

• Methylation inhibitor therapy in the treatment of myelodysplastic syndrome.

  Nature clinical practice. Oncology 20051201

• Optimizing therapy with methylation inhibitors in myelodysplastic syndromes: dose, duration, and patient selection.

  Nature clinical practice. Oncology 20051201

• Inhibitors of DNA methylation: beyond myelodysplastic syndromes.

  Nature clinical practice. Oncology 20051201

• DNA methylation and gene silencing in cancer.

  Nature clinical practice. Oncology 20051201

• [The synergistic inhibitory effect of 5-aza-2-deoxycytidine and Tamoxifen on estrogen receptor alpha negative breast cancer cell lines in vitro].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20051201

• Epigenetic and classical activation of Entamoeba histolytica heat shock protein 100 (EHsp100) expression.

  FEBS letters 20051121

• RARbeta1': primed to fight retinoid resistance in lung carcinogenesis.

  Journal of the National Cancer Institute 20051116

• A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis.

  Journal of the National Cancer Institute 20051116

• Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy.

  Oncogene 20051110

• {gamma}-Globin gene expression in chemical inducer of dimerization (CID)-dependent multipotential cells established from human {beta}-globin locus yeast artificial chromosome ({beta}-YAC) transgenic mice.

  The Journal of biological chemistry 20051104

• Multiple markers for melanoma progression regulated by DNA methylation: insights from transcriptomic studies.

  Carcinogenesis 20051101

• Hyperacetylation enhances the growth-inhibitory effect of all-trans retinoic acid by the restoration of retinoic acid receptor beta expression in head and neck squamous carcinoma (HNSCC) cells.

  Cancer chemotherapy and pharmacology 20051101

• Management of patients with higher risk myelodysplastic syndromes.

  Critical reviews in oncology/hematology 20051101

• The epigenome as a molecular marker and target.

  Cancer 20051101

• Fusion of bone marrow-derived stem cells with cardiomyocytes in a heterologous in vitro model.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20051101

• Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period.

  Xenotransplantation 20051101

• Increasing donor age adversely impacts beneficial effects of bone marrow but not smooth muscle myocardial cell therapy.

  American journal of physiology. Heart and circulatory physiology 20051101

• Tissue-specific and de novo promoter methylation of the mouse glucose transporter 2.

  Biological & pharmaceutical bulletin 20051101

• The methyltransferase inhibitor 5-aza-2-deoxycytidine induces apoptosis via induction of 15-lipoxygenase-1 in colorectal cancer cells.

  Molecular cancer therapeutics 20051101

• DNA methylation is not necessary for the inactivation of the Tam3 transposon at non-permissive temperature in Antirrhinum.

  Journal of plant physiology 20051101

• [Growth inhibition and demethylation by a component of natural drug, CDP, in cancer cell lines].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101

• New agents in the treatment of MDS.

  Clinical advances in hematology & oncology : H&O 20051101

• Passage-restricted differentiation potential of mesenchymal stem cells into cardiomyocyte-like cells.

  Biochemical and biophysical research communications 20051028

• DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation.

  Cancer 20051015

• The DNA demethylating 5-azaC induces endoreduplication in cultured Chinese hamster cells.

  Mutation research 20051015

• Hypermethylation of 18S and 28S ribosomal DNAs predicts progression-free survival in patients with ovarian cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051015

• Differential promotion of glutamate transporter expression and function by glucocorticoids in astrocytes from various brain regions.

  The Journal of biological chemistry 20051014

• Estimating the total mouse DNA methylation according to the B1 repetitive elements.

  Biochemical and biophysical research communications 20051007

• Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer.

  Oncogene 20051006

• DNA methylation increases throughout Arabidopsis development.

  Planta 20051001

• Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines.

  Gynecologic oncology 20051001

• The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents.

  International journal of oncology 20051001

• Frequent hemizygous deletion at 1p36 and hypermethylation downregulate RUNX3 expression in human lung cancer cell lines.

  Oncology reports 20051001

• 5-aza-2'-deoxycytidine sensitizes hepatoma and pancreatic cancer cell lines.

  Oncology reports 20051001

• 5-azacytidine and decitabine monotherapies of myelodysplastic disorders.

  The Annals of pharmacotherapy 20051001

• Trapped in action: direct visualization of DNA methyltransferase activity in living cells.

  Nature methods 20051001

• Potentiation of in vitro ara-C cytotoxicity by ribonucleotide reductase inhibitors, cyclin-dependent kinase modulators and the DNA repair inhibitor aphidicolin in paediatric acute myeloid leukaemia.

  British journal of haematology 20051001

• Reversal of hypermethylation and reactivation of p16INK4a, RARbeta, and MGMT genes by genistein and other isoflavones from soy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051001

• Activator protein 2alpha status determines the chemosensitivity of cancer cells: implications in cancer chemotherapy.

  Cancer research 20051001

• The cell cycle checkpoint gene Rad9 is a novel oncogene activated by 11q13 amplification and DNA methylation in breast cancer.

  Cancer research 20051001

• Epigenetic drugs: a longstanding story.

  Seminars in oncology 20051001

• Epigenetic therapy of cancer with 5-aza-2'-deoxycytidine (decitabine).

  Seminars in oncology 20051001

• Innovative approaches to the clinical development of DNA methylation inhibitors as epigenetic remodeling drugs.

  Seminars in oncology 20051001

• Clinical development of decitabine as a prototype for an epigenetic drug program.

  Seminars in oncology 20051001

• Epigenetic treatment of hematopoietic malignancies: in vivo targets of demethylating agents.

  Seminars in oncology 20051001

• [Inhibitory effect of 5-Aza-2'-deoxycytidine on human nasopharyngeal carcinoma xenograft in nude mice].

  Ai zheng = Aizheng = Chinese journal of cancer 20051001

• Down-regulation of DNA mismatch repair proteins in human and murine tumor spheroids: implications for multicellular resistance to alkylating agents.

  Molecular cancer therapeutics 20051001

• Antimitogenic and chemosensitizing effects of the methylation inhibitor zebularine in ovarian cancer.

  Molecular cancer therapeutics 20051001

• Comparison of biological effects of non-nucleoside DNA methylation inhibitors versus 5-aza-2'-deoxycytidine.

  Molecular cancer therapeutics 20051001

• Epigenetic therapy with decitabine for myelodysplasia and leukemia.

  Future oncology (London, England) 20051001

• Prolonged transcriptional silencing and CpG methylation induced by siRNAs targeted to the HIV-1 promoter region.

  Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 20051001

• Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing.

  Cancer letters 20050928

• Epigenetic basis for the transcriptional hyporesponsiveness of the human inducible nitric oxide synthase gene in vascular endothelial cells.

  Journal of immunology (Baltimore, Md. : 1950) 20050915

• The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer.

  Cancer research 20050915

• GADD45 deregulation in cancer: frequently methylated tumor suppressors and potential therapeutic targets.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050915

• The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050915

• Insensitivity to transforming growth factor-beta results from promoter methylation of cognate receptors in human prostate cancer cells (LNCaP).

  Molecular endocrinology (Baltimore, Md.) 20050901

• Genetic and epigenetic alterations of RB2/p130 tumor suppressor gene in human sporadic retinoblastoma: implications for pathogenesis and therapeutic approach.

  Oncogene 20050901

• Conditional expression of the CTCF-paralogous transcriptional factor BORIS in normal cells results in demethylation and derepression of MAGE-A1 and reactivation of other cancer-testis genes.

  Cancer research 20050901

• Strategies for biology- and molecular-based treatment of myelodysplastic syndromes.

  Current drug targets 20050901

• DNA methylation in the treatment of hematologic malignancies.

  Clinical advances in hematology & oncology : H&O 20050901

• CpG methylation of the PAI-1 gene 5'-flanking region is inversely correlated with PAI-1 mRNA levels in human cell lines.

  Thrombosis and haemostasis 20050901

• Hypermethylation of the RUNX3 gene in hepatocellular carcinoma.

  Experimental & molecular medicine 20050831

• Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.

  Circulation 20050830

• Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.

  British journal of cancer 20050822

• Characterization of DNA demethylation effects induced by 5-Aza-2'-deoxycytidine in patients with myelodysplastic syndrome.

  Cancer research 20050815

• Cytochrome P450 1B1 is overexpressed and regulated by hypomethylation in prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050815

• P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050815

• Clinicopathologic and prognostic values of apolipoprotein D alterations in hepatocellular carcinoma.

  International journal of cancer 20050810

• Granulocyte-macrophage colony-stimulating factor induces de novo methylation of the p15 CpG island in hematopoietic cells.

  Cytokine 20050807

• Myostatin inhibits myogenesis and promotes adipogenesis in C3H 10T(1/2) mesenchymal multipotent cells.

  Endocrinology 20050801

• Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.

  Leukemia 20050801

• Genomic screens for genes upregulated by demethylation in colorectal cancer: possible usefulness for clinical application.

  International journal of oncology 20050801

• Azacitidine: a novel agent for myelodysplastic syndromes.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050801

• Methylation-associated silencing of death-associated protein kinase gene in laryngeal squamous cell cancer.

  The Laryngoscope 20050801

• Advances in myelodysplastic syndrome: nursing implications of azacitidine.

  Clinical journal of oncology nursing 20050801

• Conventional and new treatment options for myelofibrosis with myeloid metaplasia.

  Seminars in oncology 20050801

• CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells.

  The Journal of biological chemistry 20050729

• Silencing of the Tropomyosin-1 gene by DNA methylation alters tumor suppressor function of TGF-beta.

  Oncogene 20050728

• Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene.

  Biochimica et biophysica acta 20050725

• Release of methyl CpG binding proteins and histone deacetylase 1 from the Estrogen receptor alpha (ER) promoter upon reactivation in ER-negative human breast cancer cells.

  Molecular endocrinology (Baltimore, Md.) 20050701

• The expression of endothelial nitric-oxide synthase is controlled by a cell-specific histone code.

  The Journal of biological chemistry 20050701

• Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells.

  Biochemical pharmacology 20050701

• DNA methylation disturbances as novel therapeutic target in lung cancer: preclinical and clinical results.

  Critical reviews in oncology/hematology 20050701

• KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis.

  Antiviral research 20050701

• CpG methylation at promoter site -140 inactivates TGFbeta2 receptor gene in prostate cancer.

  Cancer 20050701

• Resistance to Fas-mediated apoptosis is restored by cycloheximide through the downregulation of cellular FLIPL in NK/T-cell lymphoma.

  Laboratory investigation; a journal of technical methods and pathology 20050701

• Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid.

  Leukemia research 20050701

• Methylation of the MLH1 gene in hematological malignancies.

  Oncology reports 20050701

• The tissue-specific methylation of the human tyrosine hydroxylase gene reveals new regulatory elements in the first exon.

  Journal of neurochemistry 20050701

• Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms.

  Cancer biology & therapy 20050701

• Epigenetic down-regulation of CDKN1C/p57KIP2 in pancreatic ductal neoplasms identified by gene expression profiling.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050701

• Introduction: emerging role of epigenetic therapy: focus on decitabine.

  Seminars in hematology 20050701

• Decitabine dosing schedules.

  Seminars in hematology 20050701

• Decitabine in myelodysplastic syndromes.

  Seminars in hematology 20050701

• Decitabine in acute myeloid leukemia.

  Seminars in hematology 20050701

• Decitabine in chronic leukemias.

  Seminars in hematology 20050701

• Pharmacology of 5-Aza-2'-deoxycytidine (decitabine).

  Seminars in hematology 20050701

• Induction of HLA-G expression in a melanoma cell line OCM-1A following the treatment with 5-aza-2'-deoxycytidine.

  Cell research 20050701

• Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.

  The Journal of biological chemistry 20050617

• Evaluation of a 7-day continuous intravenous infusion of decitabine: inhibition of promoter-specific and global genomic DNA methylation.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• Pharmacokinetics of 5-azacitidine administered with phenylbutyrate in patients with refractory solid tumors or hematologic malignancies.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050610

• Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma.

  British journal of cancer 20050606

• Collagen alpha1(I) gene (COL1A1) is repressed by RFX family.

  The Journal of biological chemistry 20050603

• Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancer.

  Genes, chromosomes & cancer 20050601

• DNA hypomethylation in 5-azacytidine-induced early-flowering lines of flax.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20050601

• Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes.

  International immunology 20050601

• Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions.

  Plant physiology and biochemistry : PPB 20050601

• Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.

  Cancer research 20050601

• Methylation silencing of the Apaf-1 gene in acute leukemia.

  Molecular cancer research : MCR 20050601

• Contribution of epigenetic silencing of tumor necrosis factor-related apoptosis inducing ligand receptor 1 (DR4) to TRAIL resistance and ovarian cancer.

  Molecular cancer research : MCR 20050601

• Differentiation, engraftment and functional effects of pre-treated mesenchymal stem cells in a rat myocardial infarct model.

  Acta cardiologica 20050601

• Characterisation of human histone H1x.

  Biological chemistry 20050601

• Organization, not duplication, triggers silencing in a complex transgene locus in rice.

  Plant molecular biology 20050601

• 5-Azacytidine suppresses RNA polymerase II recruitment to the SLPI gene.

  Biochemical and biophysical research communications 20050527

• CRD-BP/IMP1 expression characterizes cord blood CD34+ stem cells and affects c-myc and IGF-II expression in MCF-7 cancer cells.

  The Journal of biological chemistry 20050520

• Approval summary: azacitidine for treatment of myelodysplastic syndrome subtypes.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050515

• 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.

  International journal of cancer 20050501

• Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments.

  European journal of human genetics : EJHG 20050501

• A two-edged role for the transposable element Kiddo in the rice ubiquitin2 promoter.

  The Plant cell 20050501

• Loss of caspase-1 gene expression in human gastric carcinomas and cell lines.

  International journal of oncology 20050501

• Bioavailability of azacitidine subcutaneous versus intravenous in patients with the myelodysplastic syndromes.

  Journal of clinical pharmacology 20050501

• New agents in myelodysplastic syndromes.

  Current hematology reports 20050501

• RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression.

  Cancer research 20050501

• Azacitidine-induced interstitial and alveolar fibrosis in a patient with myelodysplastic syndrome.

  Pharmacotherapy 20050501

• The controversial denouement of vertebrate DNA methylation research.

  Biochemistry. Biokhimiia 20050501

• Azacitidine.

  Nature reviews. Drug discovery 20050501

• Stimulation of P19CL6 with multiple reagents induces pulsating particles in vivo.

  Current medical research and opinion 20050501

• Methylation of CpG islands in the rat 7-dehydrocholesterol reductase promoter suppresses transcriptional activation.

  Molecules and cells 20050430

• De novo DNA methyltransferases Dnmt3a and Dnmt3b primarily mediate the cytotoxic effect of 5-aza-2'-deoxycytidine.

  Oncogene 20050428

• Altered expression of topoisomerase IIalpha contributes to cross-resistant to etoposide K562/MX2 cell line by aberrant methylation.

  British journal of cancer 20050425

• Epigenetic alteration at the DLK1-GTL2 imprinted domain in human neoplasia: analysis of neuroblastoma, phaeochromocytoma and Wilms' tumour.

  British journal of cancer 20050425

• Role of histone deacetylation in cell-specific expression of endothelial nitric-oxide synthase.

  The Journal of biological chemistry 20050422

• Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.

  Human molecular genetics 20050415

• Co-culture of human CD34+ cells with mesenchymal stem cells increases the survival of CD34+ cells against the 5-aza-deoxycytidine- or trichostatin A-induced cell death.

  Biochemical and biophysical research communications 20050415

• Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.

  Oncogene 20050414

• Methylation and acetylation characteristics of cloned bovine embryos from donor cells treated with 5-aza-2'-deoxycytidine.

  Biology of reproduction 20050401

• Hypermethylation of the promoter region is associated with the loss of MEG3 gene expression in human pituitary tumors.

  The Journal of clinical endocrinology and metabolism 20050401

• Epigenetic and genetic alterations of p33ING1b in ovarian cancer.

  Carcinogenesis 20050401

• An intron GATA-binding site regulates chromatin accessibility and is essential for IL-4 gene expression in mast cells.

  European journal of immunology 20050401

• Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.

  International journal of oncology 20050401

• Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency.

  International journal of oncology 20050401

• Methylation of the CA9 promoter can modulate expression of the tumor-associated carbonic anhydrase IX in dense carcinoma cell lines.

  International journal of oncology 20050401

• Status of reduced expression and hypermethylation of the APC tumor suppressor gene in human oral squamous cell carcinoma.

  International journal of molecular medicine 20050401

• Adult murine skeletal muscle contains cells that can differentiate into beating cardiomyocytes in vitro.

  PLoS biology 20050401

• Effect of 5-azacytidine and procainamide on CD3-zeta chain expression in Jurkat T cells.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20050401

• Histone deacetylase inhibitors decrease DNA methyltransferase-3B messenger RNA stability and down-regulate de novo DNA methyltransferase activity in human endometrial cells.

  Cancer research 20050401

• Reversible conversion of immortal human cells from telomerase-positive to telomerase-negative cells.

  Cancer research 20050401

• Alchemy and the new age of cardiac muscle cell biology.

  PLoS biology 20050401

• [Analysis of the methylation in the promoter of LRP15 gene and its expression].

  Zhongguo shi yan xue ye xue za zhi 20050401

• Azacitidine.

  Nature reviews. Drug discovery 20050401

• Aberrant CpG island hypermethylation profile is associated with atypical and anaplastic meningiomas.

  Human pathology 20050401

• Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells.

  Oncogene 20050331

• Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour.

  British journal of cancer 20050328

• Discovery of aberrant expression of R-RAS by cancer-linked DNA hypomethylation in gastric cancer using microarrays.

  Cancer research 20050315

• Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.

  Oncogene 20050310

• Regulation of replication at the R/G chromosomal band boundary and pericentromeric heterochromatin of mammalian cells.

  Experimental cell research 20050310

• Cytokine preconditioning promotes codifferentiation of human fetal liver CD133+ stem cells into angiomyogenic tissue.

  Circulation 20050308

• Downregulation of 14-3-3sigma in ovary, prostate and endometrial carcinomas is associated with CpG island methylation.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20050301

• Cell type-specific regulation of the TGF-beta-responsive alpha2(I) collagen gene by CpG methylation.

  Journal of cellular physiology 20050301

• Expression of aquaporin-5 in and fluid secretion from immortalized human salivary gland ductal cells by treatment with 5-aza-2'-deoxycytidine: a possibility for improvement of xerostomia in patients with Sjögren's syndrome.

  Laboratory investigation; a journal of technical methods and pathology 20050301

• Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia.

  Anti-cancer drugs 20050301

• Aberrant methylation of Reprimo in lung cancer.

  Lung cancer (Amsterdam, Netherlands) 20050301

• Epigenetic up-regulation of C-C chemokine receptor 7 and C-X-C chemokine receptor 4 expression in melanoma cells.

  Cancer research 20050301

• Potent selection of antigen loss variants of B16 melanoma following inflammatory killing of melanocytes in vivo.

  Cancer research 20050301

• Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

  Molecular cancer therapeutics 20050301

• FDA drug approval summary: azacitidine (5-azacytidine, Vidaza) for injectable suspension.

  The oncologist 20050301

• Epigenetic silencing of the protocadherin family member PCDH-gamma-A11 in astrocytomas.

  Neoplasia (New York, N.Y.) 20050301

• The essential role of histone H3 Lys9 di-methylation and MeCP2 binding in MGMT silencing with poor DNA methylation of the promoter CpG island.

  Journal of biochemistry 20050301

• Structural and functional preservation of specific sequences of DNA and mRNA in apoptotic bodies from ES cells.

  Apoptosis : an international journal on programmed cell death 20050301

• [5-Aza-2'-deoxycytidine enhances differentiation and apoptosis induced by phenylbutyrate in Kasumi-1 cells].

  Zhonghua zhong liu za zhi [Chinese journal of oncology] 20050301

• Therapeutic epigenetics: an emerging clinical approach to hematologic malignancies.

  Clinical advances in hematology & oncology : H&O 20050301

• Hypermethylation of the 5' CpG island of the gene encoding the serine protease Testisin promotes its loss in testicular tumorigenesis.

  British journal of cancer 20050227

• Reactivation of SYK expression by inhibition of DNA methylation suppresses breast cancer cell invasiveness.

  International journal of cancer 20050210

• Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies.

  International journal of cancer 20050210

• In vivo haematopoietic activity is induced in neurosphere cells by chromatin-modifying agents.

  The EMBO journal 20050209

• Differential properties of dentate gyrus and CA1 neural precursors.

  Journal of neurobiology 20050205

• Methylation-regulated expression of cancer testis antigens in primary effusion lymphoma: immunotherapeutic implications.

  Journal of cellular physiology 20050201

• Oncogene regulation of tumor suppressor genes in tumorigenesis.

  Carcinogenesis 20050201

• Demethylation using the epigenetic modifier, 5-azacytidine, increases the efficiency of transient transfection of macrophages.

  Journal of lipid research 20050201

• Silencing of the maternally imprinted tumor suppressor ARHI contributes to follicular thyroid carcinogenesis.

  The Journal of clinical endocrinology and metabolism 20050201

• 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.

  The Journal of pharmacology and experimental therapeutics 20050201

• Quasispecies dynamics and RNA virus extinction.

  Virus research 20050201

• Action of mutagenic agents and antiviral inhibitors on foot-and-mouth disease virus.

  Virus research 20050201

• Reversing the silencing of reporter sodium/iodide symporter transgene for stem cell tracking.

  Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201

• [Experimental study of differentiation of mouse bone marrow stromal stem cells into progenitor cardiomyocyte in vitro].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20050201

• Aberrant methylation and silencing of the BNIP3 gene in colorectal and gastric cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050201

• Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050201

• Silencing of the thrombomodulin gene in human malignant melanoma.

  Melanoma research 20050201

• Activation of CMV promoter-controlled glycosyltransferase and beta -galactosidase glycogenes by butyrate, tricostatin A, and 5-aza-2'-deoxycytidine.

  Glycoconjugate journal 20050201

• [Differentiation of mesenchymal stem cells into cardio myogenic cells under the induction of myocardial cell lysate].

  Zhonghua xin xue guan bing za zhi 20050201

• MDS: practical treatment approaches for physicians and nurses.

  Clinical advances in hematology & oncology : H&O 20050201

• Azacitine (vidaza) for myelodysplastic syndrome.

  The Medical letter on drugs and therapeutics 20050131

• Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.

  Oncogene 20050127

• Restoration of expression of transforming growth factor-beta type II receptor in murine renal cell carcinoma (renca) cells by 5-Aza-2'-deoxycytidine.

  Life sciences 20050121

• Silencing of the retinoid response gene TIG1 by promoter hypermethylation in nasopharyngeal carcinoma.

  International journal of cancer 20050120

• Characterization of {gamma}-aminobutyric acid type A receptor-associated protein, a novel tumor suppressor, showing reduced expression in breast cancer.

  Cancer research 20050115

• Methylation of the gamma-catenin gene is associated with poor prognosis of renal cell carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050115

• Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.

  Oncogene 20050106

• Downregulation of connexin 26 in human lung cancer is related to promoter methylation.

  International journal of cancer 20050101

• Induction of gene expression by 5-Aza-2'-deoxycytidine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) but not epithelial cells by DNA-methylation-dependent and -independent mechanisms.

  Leukemia 20050101

• Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma.

  Leukemia research 20050101

• DNA methylation and cancer therapy: new developments and expectations.

  Current opinion in oncology 20050101

• Morphological, electrophysiological and coupling characteristics of bone marrow-derived mononuclear cells-an in vitro-model.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050101

• Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing.

  Investigative ophthalmology & visual science 20050101

• Epigenetic regulation of O6-methylguanine-DNA methyltransferase gene expression by histone acetylation and methyl-CpG binding proteins.

  Molecular cancer therapeutics 20050101

• Formation of embryogenic cell clumps from carrot epidermal cells is suppressed by 5-azacytidine, a DNA methylation inhibitor.

  Journal of plant physiology 20050101

• [Experimental study on the myogenic differentiation of marrow mesenchymal stem cells in the local muscle tissues].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20050101

• Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma.

  Neoplasia (New York, N.Y.) 20050101

• Differentiation 'in vitro' of primary and immortalized porcine mesenchymal stem cells into cardiomyocytes for cell transplantation.

  Transplantation proceedings 20050101

• Abrogation of DUSP6 by hypermethylation in human pancreatic cancer.

  Journal of human genetics 20050101

• A phase I study of hydralazine to demethylate and reactivate the expression of tumor suppressor genes.

  BMC cancer 20050101

• Inhibition of chromatin condensation prevents transgene silencing in a neural progenitor cell line transplanted to the rat brain.

  Cell transplantation 20050101

• A transcriptome map of cellular transformation by the fos oncogene.

  Molecular cancer 20050101

• CpG-island fragments from the HNRPA2B1/CBX3 genomic locus reduce silencing and enhance transgene expression from the hCMV promoter/enhancer in mammalian cells.

  BMC biotechnology 20050101

• Azacitidine: in myelodysplastic syndromes.

  Drugs 20050101

• X-inactivation status varies in human embryonic stem cell lines.

  Stem cells (Dayton, Ohio) 20050101

• Epigenetic inactivation and aberrant transcription of CSMD1 in squamous cell carcinoma cell lines.

  Cancer cell international 20050101

• Epigenetic predisposition to expression of TIMP1 from the human inactive X chromosome.

  BMC genetics 20050101

• Rumex acetosa Y chromosomes: constitutive or facultative heterochromatin?

  Folia histochemica et cytobiologica 20050101

• Histone deacetylation is directly involved in desilencing the expression of the catalytic subunit of telomerase in normal lung fibroblast.

  Journal of cellular and molecular medicine 20050101

• Epigenetics of cervical cancer. An overview and therapeutic perspectives.

  Molecular cancer 20050101

• Update on supportive care and new therapies: immunomodulatory drugs, growth factors and epigenetic-acting agents.

  Hematology. American Society of Hematology. Education Program 20050101

• Lack of cardiac differentiation in c-kit-enriched porcine bone marrow and spleen hematopoietic cell cultures using 5-azacytidine.

  Cells, tissues, organs 20050101

• Pharmacological induction of fetal hemoglobin: Why haven't we been more successful in thalassemia?

  Annals of the New York Academy of Sciences 20050101

• Transformation of revertant murine cells by 5-azacytidine results in rapid inhibition of lysyl oxidase expression.

  Acta microbiologica et immunologica Hungarica 20050101

• 5-azacytidine induces cardiac differentiation of P19 embryonic stem cells.

  Experimental & molecular medicine 20041231

• Quantification of 5-azacytidine in plasma by electrospray tandem mass spectrometry coupled with high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Establishment of a detection system for demethylating agents using an endogenous promoter CpG island.

  Mutation research 20041221

• Inactivation of the hMSH3 mismatch repair gene in bladder cancer.

  Biochemical and biophysical research communications 20041217

• Intratumor heterogeneity of cancer/testis antigens expression in human cutaneous melanoma is methylation-regulated and functionally reverted by 5-aza-2'-deoxycytidine.

  Cancer research 20041215

• Regulation of Chk2 gene expression in lymphoid malignancies: involvement of epigenetic mechanisms in Hodgkin's lymphoma cell lines.

  Cell death and differentiation 20041201

• Genome-wide demethylation destabilizes CTG.CAG trinucleotide repeats in mammalian cells.

  Human molecular genetics 20041201

• Nonclonal neutrophil responses after successful treatment of myelodysplasia with low-dose 5-aza-2'-deoxycytidine (decitabine).

  Leukemia research 20041201

• DNA methyltransferase inhibitors in myelodysplastic syndrome.

  Best practice & research. Clinical haematology 20041201

• Histone deacetylase inhibitors in myelodysplastic syndrome.

  Best practice & research. Clinical haematology 20041201

• Zebularine: a new drug for epigenetic therapy.

  Biochemical Society transactions 20041201

• DNA methylation affects cell proliferation, cortisol secretion and steroidogenic gene expression in human adrenocortical NCI-H295R cells.

  Journal of molecular endocrinology 20041201

• Decitabine. MGI Pharma Inc/SuperGen Inc.

  IDrugs : the investigational drugs journal 20041201

• Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells.

  Molecular cancer research : MCR 20041201

• Caspase-8 gene expression in neuroblastoma.

  Annals of the New York Academy of Sciences 20041201

• Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells.

  Cancer biology & therapy 20041201

• Translational research in myelodysplastic syndromes.

  Reviews in clinical and experimental hematology 20041201

• Expression and regulation of MIM (Missing In Metastasis), a novel putative metastasis suppressor gene, and MIM-B, in bladder cancer cell lines.

  Cancer letters 20041125

• Silencing the critics: new studies move closer to answering epigenetic questions.

  Journal of the National Cancer Institute 20041117

• Epigenetic silencing of the immunoglobulin heavy-chain gene in classical Hodgkin lymphoma-derived cell lines contributes to the loss of immunoglobulin expression.

  Blood 20041115

• Investigation of the role of SDHB inactivation in sporadic phaeochromocytoma and neuroblastoma.

  British journal of cancer 20041115

• Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041115

• Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells.

  Biochemical and biophysical research communications 20041112

• Loss of maspin expression is associated with development and progression of gastric carcinoma with p53 abnormality.

  Oncology reports 20041101

• Epigenetic silencing of E- and P-cadherin gene expression in human melanoma cell lines.

  International journal of oncology 20041101

• 5-Azacytidine supports the long-term repopulating activity of cord blood CD34(+) cells.

  American journal of hematology 20041101

• Hypermethylation of growth arrest DNA damage-inducible gene 45 beta promoter in human hepatocellular carcinoma.

  The American journal of pathology 20041101

• Effects of DNA methylation inhibitor on down-regulation of ribonuclease inhibitor expression in cancer cell lines.

  Ai zheng = Aizheng = Chinese journal of cancer 20041101

• [Research on the growth inhibition of T47D cell and reversion of p16 hypermethylation by CDP].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20041101

• Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.

  Gene 20041027

• Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancer.

  International journal of cancer 20041020

• Sp17 gene expression in myeloma cells is regulated by promoter methylation.

  British journal of cancer 20041018

• Epigenetic regulation of 11 beta-hydroxysteroid dehydrogenase type 2 expression.

  The Journal of clinical investigation 20041015

• The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041015

• Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041015

• Identification of an epigenetically silenced gene, RFX1, in human glioma cells using restriction landmark genomic scanning.

  Oncogene 20041014

• Demethylating agent, 5-azacytidine, reverses differentiation of embryonic stem cells.

  Biochemical and biophysical research communications 20041008

• Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin.

  British journal of cancer 20041004

• Microarray analysis of gene regulation in the Hepa1c1c7 cell line following exposure to the DNA methylation inhibitor 5-aza-2'-deoxycytidine and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  Toxicology in vitro : an international journal published in association with BIBRA 20041001

• Maternal chromatin remodeling during maturation and after fertilization in mouse oocytes.

  Molecular reproduction and development 20041001

• Aberrant methylation of RASSF4/AD037 in nasopharyngeal carcinoma.

  Oncology reports 20041001

• Sp1-mediated transcriptional control of fibroblast growth factor receptor 4 in sarcomas of skeletal muscle lineage.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20041001

• Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.

  Cancer cell 20041001

• [Methylation of mismatch repair gene (MMR) in primary hepatocellular carcinoma].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20041001

• Clinical studies with fetal hemoglobin-enhancing agents in sickle cell disease.

  Seminars in hematology 20041001

• The role of fetal hemoglobin-enhancing agents in thalassemia.

  Seminars in hematology 20041001

• Issues regarding study design for initial clinical trials using decitabine.

  Seminars in hematology 20041001

• Clinical and oncologic implications in epigenetic down-regulation of CD26/dipeptidyl peptidase IV in adult T-cell leukemia cells.

  International journal of hematology 20041001

• 5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells.

  Oncogene 20040902

• Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.

  American journal of physiology. Gastrointestinal and liver physiology 20040901

• Changes in DNA methylation during somatic embryogenesis in Cucurbita pepo L.

  Plant cell reports 20040901

• Effect of paternal tamoxifen on the expression of insulin-like growth factor 2 and insulin-like growth factor type 1 receptor in the post-implantation rat embryos.

  Molecular reproduction and development 20040901

• Demethylating agent 5-aza-2'-deoxycytidine enhances expression of TNFRI and promotes TNF-mediated apoptosis in vitro and in vivo.

  Oncology reports 20040901

• Enhanced sensitivity of prostate cancer DU145 cells to cisplatinum by 5-aza-2'-deoxycytidine.

  Oncology reports 20040901

• Prevalent hyper-methylation of the CDH13 gene promoter in malignant B cell lymphomas.

  International journal of oncology 20040901

• DNA hypo-methylating agents and sickle cell disease.

  British journal of haematology 20040901

• CpG hypermethylation of MDR1 gene contributes to the pathogenesis and progression of human prostate cancer.

  Cancer research 20040901

• Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040901

• Methylation-associated silencing of the Wnt antagonist SFRP1 gene in human ovarian cancers.

  Cancer science 20040901

• DNA hypomethylation induced by non-genotoxic carcinogens in mouse and rat colon.

  Cancer letters 20040830

• S100A6 (Calcyclin) is a prostate basal cell marker absent in prostate cancer and its precursors.

  British journal of cancer 20040816

• The cell-specific expression of endothelial nitric-oxide synthase: a role for DNA methylation.

  The Journal of biological chemistry 20040813

• Expression of the human myotonic dystrophy kinase-related Cdc42-binding kinase gamma is regulated by promoter DNA methylation and Sp1 binding.

  The Journal of biological chemistry 20040813

• The frequent expression of cancer/testis antigens provides opportunities for immunotherapeutic targeting of sarcoma.

  Cancer immunity 20040809

• Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells.

  Laboratory investigation; a journal of technical methods and pathology 20040801

• Myelodysplasia, megakaryocytes, and methylation.

  Leukemia research 20040801

• The effects of 5-aza-2'-deoxycytidine (Decitabine) on the platelet count in patients with intermediate and high-risk myelodysplastic syndromes.

  Leukemia research 20040801

• Demethylation of DNA by decitabine in cancer chemotherapy.

  Expert review of anticancer therapy 20040801

• Apoptotic speck protein-like, a highly homologous protein to apoptotic speck protein in the pyrin domain, is silenced by DNA methylation and induces apoptosis in human hepatocellular carcinoma.

  Cancer research 20040801

• Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.

  Cancer research 20040801

• [Effect of 5-aza-2'-deoxycytidine on cell of high-risk patients with myelodysplastic syndrome in vitro].

  Zhongguo shi yan xue ye xue za zhi 20040801

• DNA methylation as a therapeutic target in hematologic disorders: recent results in older patients with myelodysplasia and acute myeloid leukemia.

  International journal of hematology 20040801

• [Growth and gene expression of leukemia cell after treated with methylation inhibitor 5-aza-2'-deoxycytidine].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20040801

• Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression.

  Oncogene 20040722

• Reduced expression of small GTPases and hypermethylation of the folate binding protein gene in cisplatin-resistant cells.

  British journal of cancer 20040719

• HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells.

  Cancer research 20040715

• Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3.

  The Journal of biological chemistry 20040702

• Effects of demethylating agent 5-aza-2(')-deoxycytidine and histone deacetylase inhibitor FR901228 on maspin gene expression in oral cancer cell lines.

  Oral oncology 20040701

• MEIS 1 expression is downregulated through promoter hypermethylation in AML1-ETO acute myeloid leukemias.

  Leukemia 20040701

• Less frequent promoter hypermethylation of DLC-1 gene in primary breast cancers.

  Oncology reports 20040701

• Autologous transplantation of bone marrow mononuclear cells improved heart function after myocardial infarction.

  Acta pharmacologica Sinica 20040701

• Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro.

  Experimental biology and medicine (Maywood, N.J.) 20040701

• Loss of disialyl Lewis(a), the ligand for lymphocyte inhibitory receptor sialic acid-binding immunoglobulin-like lectin-7 (Siglec-7) associated with increased sialyl Lewis(a) expression on human colon cancers.

  Cancer research 20040701

• Methylation-associated silencing of the heat shock protein 47 gene in human neuroblastoma.

  Cancer research 20040701

• Retrovirus silencing, variegation, extinction, and memory are controlled by a dynamic interplay of multiple epigenetic modifications.

  Molecular therapy : the journal of the American Society of Gene Therapy 20040701

• Aberrant gene expression in human non small cell lung carcinoma cells exposed to demethylating agent 5-aza-2'-deoxycytidine.

  Neoplasia (New York, N.Y.) 20040701

• [Epiplastome variation of the number of chloroplasts in stomata guard cells of sugar beet (Beta vulgaris L.)].

  Genetika 20040701

• Molecular mechanisms regulating cell type specific expression of BMP/RA Inducible Neural-specific Protein-1 that suppresses cell cycle progression: roles of NRSF/REST and DNA methylation.

  Brain research. Molecular brain research 20040618

• SOCS1 and SHP1 hypermethylation in multiple myeloma: implications for epigenetic activation of the Jak/STAT pathway.

  Blood 20040615

• Epigenetic modifications affect Dnmt3L expression.

  The Biochemical journal 20040615

• Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance.

  Cancer research 20040615

• The candidate tumor suppressor gene BLU, located at the commonly deleted region 3p21.3, is an E2F-regulated, stress-responsive gene and inactivated by both epigenetic and genetic mechanisms in nasopharyngeal carcinoma.

  Oncogene 20040610

• Progesterone receptor gene inactivation and CpG island hypermethylation in human leukemia cancer cells.

  FEBS letters 20040604

• Modification of hematopoietic stem cell fate by 5aza 2'deoxycytidine and trichostatin A.

  Blood 20040601

• MDR1 promoter hypermethylation in MCF-7 human breast cancer cells: changes in chromatin structure induced by treatment with 5-Aza-cytidine.

  Cancer biology & therapy 20040601

• Promoter methylation and protein expression of the E-cadherin gene in the clinicopathologic assessment of adenoid cystic carcinoma.

  Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20040601

• Activation of a rice endogenous retrotransposon Tos17 in tissue culture is accompanied by cytosine demethylation and causes heritable alteration in methylation pattern of flanking genomic regions.

  TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20040601

• Antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and depsipeptide on Raji lymphoma cells.

  Oncology reports 20040601

• Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.

  Cancer research 20040601

• Krüppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells.

  Cancer research 20040601

• The IL-12Rbeta2 gene functions as a tumor suppressor in human B cell malignancies.

  The Journal of clinical investigation 20040601

• Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors.

  Arthritis and rheumatism 20040601

• Pharmacological induction of fetal hemoglobin synthesis using histone deacetylase inhibitors.

  Hematology (Amsterdam, Netherlands) 20040601

• Epigenetic modification regulates both expression of tumor-associated genes and cell cycle progressing in human colon cancer cell lines: Colo-320 and SW1116.

  Cell research 20040601

• Epigenetic regulation of MDR1 gene in breast cancer: CpG methylation status dominates the stable maintenance of a silent gene.

  Cancer biology & therapy 20040601

• 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

  Journal of cellular biochemistry 20040515

• RASSF1A is a target tumor suppressor from 3p21.3 in nasopharyngeal carcinoma.

  International journal of cancer 20040510

• Identification of tumour-specific epigenetic events in medulloblastoma development by hypermethylation profiling.

  Carcinogenesis 20040501

• The value of DNA methylation analysis in basic, initial toxicity assessments.

  Toxicological sciences : an official journal of the Society of Toxicology 20040501

• DNA methylation profiles of lymphoid and hematopoietic malignancies.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040501

• Gamma-catenin expression is reduced or absent in a subset of human non-small cell lung cancers, and its re-expression inhibits cell growth.

  Chest 20040501

• The epigenetic stability of the locus control region-deficient IgH locus in mouse hybridoma cells is a clonally varying, heritable feature.

  Genetics 20040501

• Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells.

  Annals of the New York Academy of Sciences 20040501

• Hypermethylation of the PTEN gene in ovarian cancer cell lines.

  Cancer letters 20040430

• Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells.

  The Journal of biological chemistry 20040423

• Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415

• Azacitidine induces demethylation of the Epstein-Barr virus genome in tumors.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040415

• Promoter methylation inhibits APC gene expression by causing changes in chromatin conformation and interfering with the binding of transcription factor CCAAT-binding factor.

  Cancer research 20040415

• Frequent alterations of Ras signaling pathway genes in sporadic malignant melanomas.

  International journal of cancer 20040410

• 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.

  The Journal of biological chemistry 20040409

• Human PinX1, a potent telomerase inhibitor, is not involved in human gastrointestinal tract carcinoma.

  Oncology reports 20040401

• Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers.

  Cancer research 20040401

• Effect of 5-azacytidine and trichostatin A on somatic centromere association in wheat.

  Genome 20040401

• Demethylation of the synuclein gamma gene CpG island in primary gastric cancers and gastric cancer cell lines.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040401

• The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040401

• Targeted therapies in myelodysplastic syndromes: ASH 2003 review.

  Seminars in hematology 20040401

• [Cardiomyocyte-like differentiation of human bone marrow mesenchymal stem cells after exposure of 5-azacytidine in vitro].

  Shi yan sheng wu xue bao 20040401

• Promoter methylation regulates cadherin switching in squamous cell carcinoma.

  Biochemical and biophysical research communications 20040319

• Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.

  Journal of the National Cancer Institute 20040317

• Hypermethylation of the 5' CpG island of the FHIT gene is associated with hyperdiploid and translocation-negative subtypes of pediatric leukemia.

  Cancer research 20040315

• Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells.

  Oncogene 20040304

• Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2'-deoxycytidine (decitabine) in hematopoietic malignancies.

  Blood 20040301

• Hypermethylation of retrotransposons in the liverwort Marchantia paleacea var. diptera.

  Plant cell reports 20040301

• Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer.

  International journal of cancer 20040301

• Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas.

  The Journal of pathology 20040301

• DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells.

  Journal of neurochemistry 20040301

• Genomic surgery for lung cancer.

  The Journal of surgical research 20040301

• Transplacental exposure to the DNA demethylating agent, 5-AZA-CdR, affects the sexual behavior of CD-1 male mice.

  Neurotoxicology 20040301

• [Differentiation of rabbit bone marrow mesenchymal stem cells into myogenic cells in vitro and expression of vascular endothelial growth factor gene after transfection].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040301

• Aberrant expression of the maspin gene associated with epigenetic modification in melanoma cells.

  The Journal of investigative dermatology 20040301

• Methylation of a CpG island within the uroplakin Ib promoter: a possible mechanism for loss of uroplakin Ib expression in bladder carcinoma.

  Neoplasia (New York, N.Y.) 20040301

• 5-Aza-2'-deoxycytidine stimulates inducible nitric oxide synthase induction in C6 astrocytoma cells.

  Brain research 20040213

• Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells.

  Circulation research 20040206

• 5-Aza-2'-deoxycytidine and paclitaxel inhibit inducible nitric oxide synthase activation in fibrosarcoma cells.

  European journal of pharmacology 20040206

• Disruption of cell-type-specific methylation at the Maspin gene promoter is frequently involved in undifferentiated thyroid cancers.

  Oncogene 20040205

• Changes in methylation pattern of NMDA receptor NR2B gene in cortical neurons after chronic ethanol treatment in mice.

  Brain research. Molecular brain research 20040205

• Mutagenicity of the cytidine analog zebularine in Escherichia coli.

  DNA repair 20040203

• CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.

  Molecular endocrinology (Baltimore, Md.) 20040201

• Inhibitory effect of methylation inhibitor 5-aza-2-deoxycytidine on bile duct cancer cell line in vivo and in vitro.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20040201

• [Effect of inhibitors for demethylation and histone deacetylase on proliferation of cell line K562 and expression of tumor related genes].

  Zhongguo shi yan xue ye xue za zhi 20040201

• Developing a genetic system in Deinococcus radiodurans for analyzing mutations.

  Genetics 20040201

• Evaluation of antineoplastic action of 5-aza-2'-deoxycytidine (Dacogen) and docetaxel (Taxotere) on human breast, lung and prostate carcinoma cell lines.

  Anti-cancer drugs 20040201

• The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine.

  Oncogene 20040122

• Expression and regulation of tumor suppressor gene maspin in human bladder cancer.

  Cancer letters 20040120

• Differentiation of skeletal muscle from pituitary folliculo-stellate cells and endocrine progenitor cells.

  Experimental cell research 20040115

• Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.

  The EMBO journal 20040114

• In vitro efficacy of combined treatment depends on the underlying mechanism of resistance in imatinib-resistant Bcr-Abl-positive cell lines.

  Blood 20040101

• Expression of the p16INK4a gene and methylation pattern of CpG sites in the promoter region in rat tumor cell lines.

  Molecular carcinogenesis 20040101

• CHFR-associated early G2/M checkpoint defects in breast cancer cells.

  Molecular carcinogenesis 20040101

• Limited gene activation in tumor and normal epithelial cells treated with the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine.

  Molecular pharmacology 20040101

• Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells.

  Experimental hematology 20040101

• Nickel-induced down-regulation of serpin by hypoxic signaling.

  Toxicology and applied pharmacology 20040101

• 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines.

  Chinese medical journal 20040101

• Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation.

  Molecular cancer research : MCR 20040101

• 5-azacitidine: An alternative treatment of myelodysplastic syndromes in patient with refractory response to hematopoietic growth factor, a case report and review of literatures.

  Hawaii medical journal 20040101

• Activation of expression of p15, p73 and E-cadherin in leukemic cells by different concentrations of 5-aza-2'-deoxycytidine (Decitabine).

  Anticancer research 20040101

• Apoptosis in plants: specific features of plant apoptotic cells and effect of various factors and agents.

  International review of cytology 20040101

• Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by phenylbutyrate on L1210 leukemic cells.

  Leukemia & lymphoma 20040101

• 5-aza-2'-deoxycytidine restores the E-cadherin system in E-cadherin-silenced cancer cells and reduces cancer metastasis.

  Clinical & experimental metastasis 20040101

• Epigenetic CRBP downregulation appears to be an evolutionarily conserved (human and mouse) and oncogene-specific phenomenon in breast cancer.

  Molecular cancer 20040101

• Role of epigenetic DNA alterations in the pathogenesis of systemic lupus erythematosus.

  Journal of applied genetics 20040101

• Region-specific chromatin decondensation and micronucleus formation induced by 5-azacytidine in human TIG-7 cells.

  Cytogenetic and genome research 20040101

• Reversal of gene silencing as a therapeutic target for cancer--roles for DNA methylation and its interdigitation with chromatin.

  Novartis Foundation symposium 20040101

• The DNA de-methylating agent 5-azacytidine does not restore CYP1A induction in PCB resistant Newark Bay killifish (Fundulus heteroclitus).

  Marine environmental research 20040101

• Formation of mitoxantrone adducts in human tumor cells: potentiation by AN-9 and DNA methylation.

  Oncology research 20040101

• Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites.

  Breast cancer research : BCR 20040101

• Regulation of major histocompatibility complex class II gene expression in trophoblast cells.

  Reproductive biology and endocrinology : RB&E 20040101

• Murine models of lupus induced by hypomethylated T cells.

  Methods in molecular medicine 20040101

• DNA methylation polymorphism in a set of elite rice cultivars and its possible contribution to inter-cultivar differential gene expression.

  Cellular & molecular biology letters 20040101

• New drug for bone marrow disease.

  FDA consumer 20040101

• Methylation profiles of thirty four promoter-CpG islands and concordant methylation behaviours of sixteen genes that may contribute to carcinogenesis of astrocytoma.

  BMC cancer 20040101

• [Effect of 5-azacytidine on the light-sensitive formation of sexual and asexual reproductive structures in wc-1 and wc-2 mutants of Neurospora crassa].

  Prikladnaia biokhimiia i mikrobiologiia 20040101

• Cytotoxicity of psammaplin A from a two-sponge association may correlate with the inhibition of DNA replication.

  BMC cancer 20040101

• Nuclei of embryonic stem cells reprogram somatic cells.

  Stem cells (Dayton, Ohio) 20040101

• Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression.

  BMC cancer 20040101

• New nucleoside analogs in the treatment of solid tumors.

  Acta poloniae pharmaceutica 20040101

• Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord.

  Stem cells (Dayton, Ohio) 20040101

• Treatment options for myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20040101

• The role of methyltransferase inhibitors in the management of the myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20040101

• Methyltransferase inhibitors: changing the treatment algorithm for myelodysplastic syndromes.

  Cancer control : journal of the Moffitt Cancer Center 20040101

• Microarray analysis of gene expression in metastatic gastric cancer cells after incubation with the methylation inhibitor 5-aza-2'-deoxycytidine.

  Clinical & experimental metastasis 20040101

• Approaches to the reactivation of hemoglobin F as a treatment for sickle cell disease.

  Clinical advances in hematology & oncology : H&O 20040101

• Azacitidine.

  Report on carcinogens : carcinogen profiles 20040101

• Hypermethylation of the Ink4b locus in murine myeloid leukemia and increased susceptibility to leukemia in p15(Ink4b)-deficient mice.

  Oncogene 20031218

• Identification of HRK as a target of epigenetic inactivation in colorectal and gastric cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20031215

• Hepatocyte growth factor activator inhibitor 2/placental bikunin (HAI-2/PB) gene is frequently hypermethylated in human hepatocellular carcinoma.

  Cancer research 20031215

• [The study of 5-Aza-2'-deoxycytidine on transcription regulation of p16/CDKN2 gene demethylation in RKO human colorectal cell line].

  Zhonghua yi xue za zhi 20031210

• Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer.

  Cancer letters 20031208

• Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation.

  Oncogene 20031204

• The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.

  American journal of respiratory cell and molecular biology 20031201

• Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease.

  Blood 20031201

• The histone code regulating expression of the imprinted mouse Igf2r gene.

  Endocrinology 20031201

• Promoter methylation of cyclin D2 gene in gastric carcinoma.

  International journal of oncology 20031201

• Changes in 5S rDNA chromatin organization and transcription during heterochromatin establishment in Arabidopsis.

  The Plant cell 20031201

• Epigenetic inactivation of TSLC1 gene in nasopharyngeal carcinoma.

  Molecular carcinogenesis 20031201

• DNA methylation in haematological malignancies: the role of decitabine.

  Expert opinion on investigational drugs 20031201

• Therapeutic strategies in gastric cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031201

• DNA methylation controls the responsiveness of hepatoma cells to leukemia inhibitory factor.

  Hepatology (Baltimore, Md.) 20031201

• Altered expression of the septin gene, SEPT9, in ovarian neoplasia.

  The Journal of pathology 20031201

• Expression of pericyte, mesangium and muscle markers in malignant rhabdoid tumor cell lines: differentiation-induction using 5-azacytidine.

  Cancer science 20031201

• Proteomic analysis of pancreatic ductal carcinoma cells treated with 5-aza-2'-deoxycytidine.

  Electrophoresis 20031201

• [DNA methylation and cancer--DNA methylation as a target of cancer chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20031201

• Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.

  Nucleosides, nucleotides & nucleic acids 20031201

• Decitabine: development of a DNA methyltransferase inhibitor for hematological malignancies.

  Current opinion in investigational drugs (London, England : 2000) 20031201

• Demethylation of host-cell DNA at the site of avian retrovirus integration.

  Biochemical and biophysical research communications 20031121

• Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).

  International journal of cancer 20031120

• Genetic and epigenetic alterations of DLC-1 gene in hepatocellular carcinoma.

  Cancer research 20031115

• Restoration of insulin-like growth factor binding protein-related protein 1 has a tumor-suppressive activity through induction of apoptosis in human prostate cancer.

  Cancer research 20031115

• Comment on 'Chromosomal instability and tumors promoted by DNA hypomethylation' and 'Induction of tumors in nice by genomic hypomethylation'.

  Science (New York, N.Y.) 20031114

• Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.

  International journal of cancer 20031110

• Silencing of CDX2 expression in colon cancer via a dominant repression pathway.

  The Journal of biological chemistry 20031107

• Decitabine induces cell cycle arrest at the G1 phase via p21(WAF1) and the G2/M phase via the p38 MAP kinase pathway.

  Leukemia research 20031101

• ASC/TMS1, a caspase-1 activating adaptor, is downregulated by aberrant methylation in human melanoma.

  International journal of cancer 20031101

• Human circulating CD14+ monocytes as a source of progenitors that exhibit mesenchymal cell differentiation.

  Journal of leukocyte biology 20031101

• Apoptosis of terminal hypertrophic chondrocytes in an in vitro model of endochondral ossification.

  The Journal of pathology 20031101

• Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.

  Cancer research 20031101

• Decitabine.

  Current opinion in oncology 20031101

• Epigenetic silencing of the HIC-1 gene in human medulloblastomas.

  Journal of neuropathology and experimental neurology 20031101

• Arabidopsis MBD proteins show different binding specificities and nuclear localization.

  Plant molecular biology 20031101

• Role of promoter methylation in regulation of the mammalian heparanase gene.

  Oncogene 20031030

• Epigenetic inactivation of RASSF1A candidate tumor suppressor gene at 3p21.3 in brain tumors.

  Oncogene 20031030

• Strategies for reversing drug resistance.

  Oncogene 20031020

• Transcriptional regulation of mouse delta-opioid receptor gene by CpG methylation: involvement of Sp3 and a methyl-CpG-binding protein, MBD2, in transcriptional repression of mouse delta-opioid receptor gene in Neuro2A cells.

  The Journal of biological chemistry 20031017

• Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells.

  Oncogene 20031016

• Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.

  Oncogene 20031009

• Inhibitors of DNA methylation and histone deacetylation activate cytomegalovirus promoter-controlled reporter gene expression in human glioblastoma cell line U87.

  Carcinogenesis 20031001

• Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres.

  Experimental cell research 20031001

• Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.

  The American journal of pathology 20031001

• Reduced expression of oestrogen receptor beta in invasive breast cancer and its re-expression using DNA methyl transferase inhibitors in a cell line model.

  The Journal of pathology 20031001

• Improvement of neurological deficits by intracerebral transplantation of human adipose tissue-derived stromal cells after cerebral ischemia in rats.

  Experimental neurology 20031001

• Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.

  Cancer research 20031001

• DNA methylation and autoimmune disease.

  Clinical immunology (Orlando, Fla.) 20031001

• Inhibitors of DNA methylation in the treatment of hematological malignancies and MDS.

  Clinical immunology (Orlando, Fla.) 20031001

• Reactivation of fetal hemoglobin in adult stem cell erythropoiesis by transforming growth factor-beta.

  Journal of hematotherapy & stem cell research 20031001

• A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.

  Breast cancer research and treatment 20031001

• Novel biospecific agents for the treatment of myelodysplastic syndromes.

  Journal of the National Comprehensive Cancer Network : JNCCN 20031001

• Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells.

  Toxicology letters 20030930

• Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells.

  The Journal of biological chemistry 20030926

• Clinicopathological significance and molecular regulation of maspin expression in ductal adenocarcinoma of the pancreas.

  Cancer letters 20030925

• Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas.

  Oncogene 20030925

• Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation.

  The Journal of biological chemistry 20030919

• Expression profiling reveals that methylation of TIMP3 is involved in uveal melanoma development.

  International journal of cancer 20030910

• Epigenetic characteristics and development of embryos cloned from donor cells treated by trichostatin A or 5-aza-2'-deoxycytidine.

  Biology of reproduction 20030901

• Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies.

  Genes, chromosomes & cancer 20030901

• Effect of promoter methylation on the regulation of IFN-gamma gene during in vitro differentiation of human peripheral blood T cells into a Th2 population.

  Journal of immunology (Baltimore, Md. : 1950) 20030901

• Epigenetic inactivation of RASSF1A in head and neck cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030901

• Differential expression of bikunin (HAI-2/PB), a proposed mediator of glioma invasion, by demethylation treatment.

  Journal of neuro-oncology 20030901

• Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control.

  Neoplasia (New York, N.Y.) 20030901

• Application of mesenchymal stem cells for the regeneration of cardiomyocyte and its use for cell transplantation therapy.

  Human cell 20030901

• Molecular cloning and characterization of human acid sensing ion channel (ASIC)2 gene promoter.

  Gene 20030814

• Alterations of BLU, a candidate tumor suppressor gene on chromosome 3p21.3, in human nasopharyngeal carcinoma.

  International journal of cancer 20030810

• Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.

  International journal of cancer 20030810

• CpG methylation-dependent repression of the human O6-methylguanine-DNA methyltransferase gene linked to chromatin structure alteration.

  Carcinogenesis 20030801

• Down-regulation of FEZ1/LZTS1 gene with frequent loss of heterozygosity in oral squamous cell carcinomas.

  International journal of oncology 20030801

• Results of decitabine (5-aza-2'deoxycytidine) therapy in 130 patients with chronic myelogenous leukemia.

  Cancer 20030801

• Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure.

  Toxicology and applied pharmacology 20030801

• Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.

  Cancer research 20030801

• Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis.

  Cancer research 20030801

• Epigenetic down-regulation of death-associated protein kinase in lung cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030801

• Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030801

• Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes.

  Bone marrow transplantation 20030801

• Effect of fetal hemoglobin-stimulating medicines on the interaction of DNA and protein of important erythroid regulatory elements.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20030801

• S-adenosyl-L-methionine is able to reverse micronucleus formation induced by sodium arsenite and other cytoskeleton disrupting agents in cultured human cells.

  Mutation research 20030725

• Promoter hypomethylation of a novel cancer/testis antigen gene CAGE is correlated with its aberrant expression and is seen in premalignant stage of gastric carcinoma.

  Biochemical and biophysical research communications 20030718

• Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.

  Oncogene 20030717

• UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines.

  Oncogene 20030717

• Frequent epigenetic inactivation of the SLIT2 gene in gliomas.

  Oncogene 20030717

• Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

  Cancer research 20030715

• Rapid deterioration in quality of life during interleukin-2- and alpha-interferon-based home therapy of renal cell carcinoma is associated with a good outcome.

  British journal of cancer 20030707

• Control mechanisms in the regulation of telomerase reverse transcriptase expression in differentiating human teratocarcinoma cells.

  Biochemical and biophysical research communications 20030704

• Induction of a senescent-like phenotype does not confer the ability of bovine immortal cells to support the development of nuclear transfer embryos.

  Biology of reproduction 20030701

• Effect of trichostatin a and 5'-azacytidine on transgene reactivation in U937 transduced cells.

  Pharmacological research 20030701

• OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer.

  Nature genetics 20030701

• Sera from liver failure patients and a demethylating agent stimulate transdifferentiation of murine bone marrow cells into hepatocytes in coculture with nonparenchymal liver cells.

  Journal of hepatology 20030701

• Epigenetic inactivation of laminin-5-encoding genes in lung cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030701

• Transcoronary implantation of bone marrow stromal cells ameliorates cardiac function after myocardial infarction.

  The Journal of thoracic and cardiovascular surgery 20030701

• Restoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells.

  Neoplasia (New York, N.Y.) 20030701

• Stable transgene expression and random gene silencing in wheat.

  Plant biotechnology journal 20030701

• Establishment and functional validation of a structural homology model for human DNA methyltransferase 1.

  Biochemical and biophysical research communications 20030627

• Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

  Oncogene 20030626

• Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia.

  International journal of cancer 20030620

• Methylation-regulated expression of HLA class I antigens in melanoma.

  International journal of cancer 20030620

• Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells.

  Oncogene 20030619

• Allelic loss on chromosome 3p21.3 and promoter hypermethylation of semaphorin 3B in non-small cell lung cancer.

  Cancer research 20030615

• Hypermethylation of the tumor suppressor gene RASSFIA and frequent concomitant loss of heterozygosity at 3p21 in cervical cancers.

  International journal of cancer 20030610

• Reconstitution of TIMP-2 expression in SH-SY5Y neuroblastoma cells by 5-azacytidine is mediated transcriptionally by NF-Y through an inverted CCAAT site.

  Experimental cell research 20030610

• Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression.

  Oncogene 20030605

• The mechanism of 3'-azido-2',3'-dideoxythymidine resistance to human lymphoid cells.

  International journal of molecular medicine 20030601

• 5-Aza-2'-deoxycytidine (decitabine) treatment of hematopoietic malignancies: a multimechanism therapeutic approach?

  Blood 20030601

• Inactivation of helicase-like transcription factor by promoter hypermethylation in human gastric cancer.

  Molecular carcinogenesis 20030601

• DNA mismatch repair genes in renal cell carcinoma.

  The Journal of urology 20030601

• Continuing primordial germ cell differentiation in the mouse embryo is a cell-intrinsic program sensitive to DNA methylation.

  Developmental biology 20030601

• Cell-autonomous mechanisms and myelin-associated factors contribute to the development of Purkinje axon intracortical plexus in the rat cerebellum.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030601

• Aberrant methylation of the vascular endothelial growth factor receptor-1 gene in prostate cancer.

  Cancer science 20030601

• Proteomic analysis of a lymphoma-derived cell line (DG75) following treatment with a demethylating drug: modification of membrane-associated proteins.

  Proteomics 20030601

• DNA methylation and chromatin structure regulate T cell perforin gene expression.

  Journal of immunology (Baltimore, Md. : 1950) 20030515

• Use of the rpoB gene to determine the specificity of base substitution mutations on the Escherichia coli chromosome.

  DNA repair 20030513

• Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma.

  International journal of cancer 20030510

• Susceptibility to postnatal growth retardation induced by 5-AZA-2'-deoxycytidine in utero: gender specificity and correlation with reduced insulin-like growth factor 1.

  Life sciences 20030509

• Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells.

  Leukemia research 20030501

• Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.

  Leukemia research 20030501

• 5-azacytidine reactivates the erythroid differentiation potential of the myeloid-restricted murine cell line 32D Ro.

  Experimental cell research 20030501

• Cytosine methylation occurs in a CDC48 homologue and a MADS-box gene during adventitious shoot induction in Petunia leaf explants.

  Journal of experimental botany 20030501

• Reactivation of tumor suppressor genes by the cardiovascular drugs hydralazine and procainamide and their potential use in cancer therapy.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030501

• Transcriptional silencing of geminiviral promoter-driven transgenes following homologous virus infection.

  Molecular plant-microbe interactions : MPMI 20030501

• Growth and differentiation of rat bone marrow stromal cells: does 5-azacytidine trigger their cardiomyogenic differentiation?

  Cardiovascular research 20030501

• The DNA methylation inhibitor 5-azacytidine modulates 6-thioguanine toxicity in mammalian cells.

  Toxicology letters 20030430

• JunB gene expression is inactivated by methylation in chronic myeloid leukemia.

  Blood 20030415

• DNA hypermethylation near the transcription start site of collagen alpha2(I) gene occurs in both cancer cell lines and primary colorectal cancers.

  Cancer research 20030415

• Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

• Methylation of TFPI-2 gene is not the sole cause of its silencing.

  International journal of oncology 20030401

• Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype.

  Leukemia 20030401

• Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030401

• Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2.

  Biochemical and biophysical research communications 20030321

• Regulatory approvals of pediatric oncology drugs: previous experience and new initiatives.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315

• Inactivation of hMLH1 and hMSH2 by promoter methylation in primary non-small cell lung tumors and matched sputum samples.

  The Journal of clinical investigation 20030315

• Inhibition of DNA methylation and reactivation of silenced genes by zebularine.

  Journal of the National Cancer Institute 20030305

• Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.

  Blood 20030301

• Long-term follow-up of a phase I study of high-dose decitabine, busulfan, and cyclophosphamide plus allogeneic transplantation for the treatment of patients with leukemias.

  Cancer 20030301

• A systematic profile of DNA methylation in human cancer cell lines.

  Cancer research 20030301

• Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patient.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20030301

• Interaction of 5-aza-2'-deoxycytidine and depsipeptide on antineoplastic activity and activation of 14-3-3sigma, E-cadherin and tissue inhibitor of metalloproteinase 3 expression in human breast carcinoma cells.

  Anti-cancer drugs 20030301

• Transformation of adult mesenchymal stem cells isolated from the fatty tissue into cardiomyocytes.

  The Annals of thoracic surgery 20030301

• Phase I trial of continuous infusion 5-aza-2'-deoxycytidine.

  Cancer chemotherapy and pharmacology 20030301

• Opposite effects of the maternal immune system activated by interleukin-1beta vs. PSK and OK432 on 5-azacytidine-induced birth defects.

  Congenital anomalies 20030301

• Epigenetics: the role of methylation in the mechanism of action of tumor suppressor genes.

  Annals of the New York Academy of Sciences 20030301

• E-cadherin expression is silenced by DNA methylation in cervical cancer cell lines and tumours.

  European journal of cancer (Oxford, England : 1990) 20030301

• Therapies to increase fetal hemoglobin in sickle cell disease.

  Current hematology reports 20030301

• Regeneration of cardiomyocytes from bone marrow: Use of mesenchymal stem cell for cardiovascular tissue engineering.

  Cytotechnology 20030301

• Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.

  Journal of the National Cancer Institute 20030219

• On the use of DNA methylation inhibitors and the reversal of transcriptional silencing.

  Blood 20030215

• CpG island methylation is a common finding in colorectal cancer cell lines.

  British journal of cancer 20030210

• Hypermethylation-mediated regulation of CD44 gene expression in human neuroblastoma.

  Genes, chromosomes & cancer 20030201

• Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells.

  International journal of oncology 20030201

• Hypomethylation of the synuclein gamma gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma.

  Cancer research 20030201

• Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma.

  Cell death and differentiation 20030201

• Latent HIV-1 reactivation in transgenic mice requires cell cycle -dependent demethylation of CREB/ATF sites in the LTR.

  AIDS (London, England) 20030124

• Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia.

  Oncogene 20030123

• Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers.

  Cancer genetics and cytogenetics 20030115

• Synergistic antineoplastic action of DNA methylation inhibitor 5-AZA-2'-deoxycytidine and histone deacetylase inhibitor depsipeptide on human breast carcinoma cells.

  International journal of cancer 20030110

• Detection of thymidylate synthase modulators by a novel screening assay.

  Molecular pharmacology 20030101

• Regulation of mouse mammary tumor virus env transcriptional activator initiated mammary tumor virus superantigen transcripts in lymphomas of SJL/J mice: role of Ikaros, demethylation, and chromatin structural change in the transcriptional activation of mammary tumor virus superantigen.

  Journal of immunology (Baltimore, Md. : 1950) 20030101

• Hypermethylation of metallothionein-3 CpG island in gastric carcinoma.

  Carcinogenesis 20030101

• Chromosomal aberrations induced by 5-azacytidine combined with VP-16 (etoposide) in CHO-K1 and XRS-5 cell lines.

  Teratogenesis, carcinogenesis, and mutagenesis 20030101

• 5-AZA-2'-deoxycytidine (5-AZA-CdR): a demethylating agent affecting development and reproductive capacity.

  Journal of applied toxicology : JAT 20030101

• Down-regulation of connexin 32 gene expression through DNA methylation in a human renal cell carcinoma cell.

  American journal of nephrology 20030101

• An epigenetic approach for finding tumor suppressors.

  Cell cycle (Georgetown, Tex.) 20030101

• Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T- and natural killer (NK)/T-cell malignancies.

  Cancer science 20030101

• Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.

  Drugs in R&D 20030101

• Inactivation of the RASSF1A in osteosarcoma.

  Oncology reports 20030101

• Induced differentiation of human cord blood mesenchymal stem/progenitor cells into cardiomyocyte-like cells in vitro.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20030101

• Reactivation of silenced genes and transcriptional therapy.

  Cytogenetic and genome research 20030101

• Forgotten fragile sites and related phenomena.

  Cytogenetic and genome research 20030101

• Synthesis of 5-azacytidine nucleosides with rigid sugar moiety as potential antitumor agents.

  Nucleosides, nucleotides & nucleic acids 20030101

• 5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.

  Journal of andrology 20030101

• Decitabine: 2'-deoxy-5-azacytidine, Aza dC, DAC, dezocitidine, NSC 127716.

  Drugs in R&D 20030101

• Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.

  Cancer biology & therapy 20030101

• Induction of the estrogen receptor by ablation of DNMT1 in ER-negative breast cancer cells.

  Cancer biology & therapy 20030101

• Hemoglobinopathies.

  Hematology. American Society of Hematology. Education Program 20030101

• Myelodysplastic syndrome.

  Hematology. American Society of Hematology. Education Program 20030101

• Positive and negative transcriptional states of a variegating immunoglobulin heavy chain (IgH) locus are maintained by a cis-acting epigenetic mechanism.

  Journal of immunology (Baltimore, Md. : 1950) 20021215

• Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

  Cancer research 20021215

• The architecture of interphase chromosomes and gene positioning are altered by changes in DNA methylation and histone acetylation.

  Journal of cell science 20021201

• An ACF1-ISWI chromatin-remodeling complex is required for DNA replication through heterochromatin.

  Nature genetics 20021201

• Induction of TRAG-3 expression in A549 lung adenocarcinoma cell line by 5-aza-2' deoxyazacytidine.

  Lung cancer (Amsterdam, Netherlands) 20021201

• Expression of Arabidopsis LINEs from two promoters.

  The Plant journal : for cell and molecular biology 20021201

• Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20021201

• DNA methylation and demethylating drugs in myelodysplastic syndromes and secondary leukemias.

  Haematologica 20021201

• Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.

  Cancer cell 20021201

• Decitabine has promising clinical activity in chronic myeloid leukemia.

  Expert review of anticancer therapy 20021201

• The human telomerase RNA gene (hTERC) is regulated during carcinogenesis but is not dependent on DNA methylation.

  Carcinogenesis 20021201

• Inhibition of growth of mouse gastric cancer cells by Runx3, a novel tumor suppressor.

  Oncogene 20021128

• Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia.

  Cytokine 20021124

• [Myelodysplastic syndromes. Diagnosis and therapeutic strategies].

  Medizinische Klinik (Munich, Germany : 1983) 20021115

• Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.

  Cancer research 20021115

• The ETS transcription factor MEF is a candidate tumor suppressor gene on the X chromosome.

  Cancer research 20021115

• DNA methyltransferase inhibitors-state of the art.

  Annals of oncology : official journal of the European Society for Medical Oncology 20021101

• Re-expression of p16 gene in the myeloma cell line U266 induced by synergy of sodium butyrate and 5-Aza-2'-deoxycytidine.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021101

• [The re-expression of p15(INK4B) gene in leukemia cells induced by in vitro DNA methyltransferase and histone deacetylase inhibition].

  Zhonghua nei ke za zhi 20021101

• New synthesis of pyrrolidine homoazasugars via aminohomologation of furanoses and their use for the stereoselective synthesis of aza-C-disaccharides.

  The Journal of organic chemistry 20021018

• Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment.

  Blood 20021015

• Crucial role of DNA methylation in determination of clonally distributed killer cell Ig-like receptor expression patterns in NK cells.

  Journal of immunology (Baltimore, Md. : 1950) 20021015

• Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

  Cancer research 20021015

• Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells.

  The Journal of biological chemistry 20021011

• Inhibition of HhaI DNA (Cytosine-C5) methyltransferase by oligodeoxyribonucleotides containing 5-aza-2'-deoxycytidine: examination of the intertwined roles of co-factor, target, transition state structure and enzyme conformation.

  Journal of molecular biology 20021011

• [Cell transplantation of 5-aza cytidine induced bone marrow stromal cells transfected by angiogenin gene ex vivo into infarcted myocardium, an experimental study].

  Zhonghua yi xue za zhi 20021010

• Treatment of myelodysplastic syndromes with 5-azacytidine.

  Leukemia research 20021001

• Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome.

  American journal of human genetics 20021001

• Evidence for local control of gene expression in the epidermal differentiation complex.

  Experimental dermatology 20021001

• Seeking a way to alleviate sickle cell disease.

  JAMA 20021001

• Phase II trial of cisplatin plus decitabine, a new DNA hypomethylating agent, in patients with advanced squamous cell carcinoma of the cervix.

  American journal of clinical oncology 20021001

• Suppression of metallothionein-I/II expression and its probable molecular mechanisms.

  Environmental health perspectives 20021001

• Reprogramming of bone marrow mesenchymal stem cells into cardiomyocytes.

  Comptes rendus biologies 20021001

• [Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent].

  Ai zheng = Aizheng = Chinese journal of cancer 20021001

• DNA methylation down-regulates CDX1 gene expression in colorectal cancer cell lines.

  The Journal of biological chemistry 20020927

• Tropomyosin-1, a novel suppressor of cellular transformation is downregulated by promoter methylation in cancer cells.

  Cancer letters 20020926

• Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells.

  Circulation research 20020920

• DNA alkylating agents alleviate silencing of class II transactivator gene expression in L1210 lymphoma cells.

  Journal of immunology (Baltimore, Md. : 1950) 20020915

• New drugs in acute myeloid leukemia.

  Current oncology reports 20020901

• Antineoplastic action of 5-aza-2'-deoxycytidine and phenylbutyrate on human lung carcinoma cells.

  Anti-cancer drugs 20020901

• Treatment of cancer cells with methioninase produces DNA hypomethylation and increases DNA synthesis.

  Cancer research 20020815

• Molecular changes associated with oral dysplasia progression and acquisition of immortality: potential for its reversal by 5-azacytidine.

  Cancer research 20020815

• 5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy.

  Oncogene 20020812

• Reactivating the expression of methylation silenced genes in human cancer.

  Oncogene 20020812

• Pseudomyxoma peritonei is a disease of MUC2-expressing goblet cells.

  The American journal of pathology 20020801

• 5-aza-2'-deoxycytidine-induced expression of functional cancer testis antigens in human renal cell carcinoma: immunotherapeutic implications.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020801

• Role of DNA methylation in transcription of human endogenous retrovirus in the pathogenesis of systemic lupus erythematosus.

  The Journal of rheumatology 20020801

• Retinoic acid receptor alpha2 is a growth suppressor epigenetically silenced in MCF-7 human breast cancer cells.

  Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020801

• What is the optimal therapy for childhood AML?

  Oncology (Williston Park, N.Y.) 20020801

• Acute rhabdomyolysis as a complication of cytarabine chemotherapy for acute myeloid leukemia: case report and review of literature.

  American journal of hematology 20020801

• 5-Azacytidine (5AzC)-induced histopathological changes in the central nervous system of rat fetuses.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020801

• [Inhibitory effect on proliferation of KG1a cell line by methyltransferase inhibitors].

  Zhongguo shi yan xue ye xue za zhi 20020801

• Identification of active antiviral compounds against a New York isolate of West Nile virus.

  Antiviral research 20020701

• Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020701

• Reduced expression of the insulin-induced protein 1 and p41 Arp2/3 complex genes in human gastric cancers.

  International journal of cancer 20020701

• SNPs in the CpG island of NAP1L2: a possible link between DNA methylation and neural tube defects?

  American journal of medical genetics 20020701

• Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine.

  Alcohol (Fayetteville, N.Y.) 20020701

• Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells.

  Oncogene 20020620

• Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers.

  British journal of cancer 20020617

• DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA.

  European journal of pharmacology 20020607

• Silencing of pi-class glutathione S-transferase in MDA PCa 2a and MDA PCa 2b cells.

  The Prostate 20020601

• Maintenance of elevated fetal hemoglobin levels by decitabine during dose interval treatment of sickle cell anemia.

  Blood 20020601

• DNA methylation dominates transcriptional silencing of Pax5 in terminally differentiated B cell lines.

  Molecular immunology 20020601

• Improved heart function with myogenesis and angiogenesis after autologous porcine bone marrow stromal cell transplantation.

  The Journal of thoracic and cardiovascular surgery 20020601

• Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids.

  Plant physiology 20020601

• DNA methylation and epigenetic inheritance.

  Methods (San Diego, Calif.) 20020601

• Mechanisms of 5-azacytidine (5AzC)-induced toxicity in the rat foetal brain.

  International journal of experimental pathology 20020601

• Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line.

  Oncogene 20020530

• Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.

  Biochemical and biophysical research communications 20020524

• In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer.

  British journal of cancer 20020520

• Treatment of myelodysplastic syndrome: questions raised by the azacitidine experience.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515

• Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515

• Impact of azacytidine on the quality of life of patients with myelodysplastic syndrome treated in a randomized phase III trial: a Cancer and Leukemia Group B study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020515

• Role of de novo DNA methyltransferases and methyl CpG-binding proteins in gene silencing in a rat hepatoma.

  The Journal of biological chemistry 20020503

• Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.

  Oncogene 20020502

• Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020501

• Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus.

  Arthritis and rheumatism 20020501

• Hypertonicity induction of melanoma antigen, a tumor-associated antigen.

  Molecules and cells 20020430

• Genetics of cellular senescence.

  Mechanisms of ageing and development 20020430

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Cell division is required for de novo methylation of CpG islands in bladder cancer cells.

  Cancer research 20020415

• Differentiation therapy for myelodysplastic syndrome.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• Silencing of GSTP1 gene by CpG island DNA hypermethylation in HBV-associated hepatocellular carcinomas.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• 5-Aza-2'-deoxycytidine-induced cytotoxicity and limb reduction defects in the mouse.

  Teratology 20020401

• Review of the clinical experience with 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumors.

  Current opinion in investigational drugs (London, England : 2000) 20020401

• Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications.

  British journal of cancer 20020318

• p16INK4a loss and sensitivity in KSHV associated primary effusion lymphoma.

  Oncogene 20020314

• High prevalence of decreased expression of KAI1 metastasis suppressor in human oral carcinogenesis.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020301

• Complex relationships between 5-aza-dC induced DNA demethylation and chromosome compaction at mitosis.

  Chromosoma 20020301

• Molecular characterization of regenerated cardiomyocytes derived from adult mesenchymal stem cells.

  Congenital anomalies 20020301

• Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma.

  Cancer letters 20020225

• Chromosomal autonomy of hMLH1 methylation in colon cancer.

  Oncogene 20020221

• Methylation-mediated silencing of TMS1/ASC is accompanied by histone hypoacetylation and CpG island-localized changes in chromatin architecture.

  The Journal of biological chemistry 20020215

• Somatic recombination: a major genotoxic effect of two pyrimidine antimetabolitic chemotherapeutic drugs in Drosophila melanogaster.

  Mutation research 20020215

• Analysis of gene induction in human fibroblasts and bladder cancer cells exposed to the methylation inhibitor 5-aza-2'-deoxycytidine.

  Cancer research 20020215

• The 5-lipoxygenase promoter is regulated by DNA methylation.

  The Journal of biological chemistry 20020208

• Cancer research. Leukemia protein spurs gene silencing.

  Science (New York, N.Y.) 20020208

• Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor.

  Science (New York, N.Y.) 20020208

• Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity.

  International journal of oncology 20020201

• Lack of IFN-gamma-mediated induction of the class II transactivator (CIITA) through promoter methylation is predominantly found in developmental tumor cell lines.

  International journal of cancer 20020201

• Chondrocytes provide morphogenic signals that selectively induce osteogenic differentiation of mesenchymal stem cells.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020201

• Expression of a human endogenous retrovirus, HERV-K, in the blood cells of leukemia patients.

  Leukemia 20020201

• 5S rRNA genes expression is not inhibited by DNA methylation in Arabidopsis.

  The Plant journal : for cell and molecular biology 20020201

• Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression.

  Immunogenetics 20020201

• Variable promoter region CpG island methylation of the putative tumor suppressor gene Connexin 26 in breast cancer.

  Carcinogenesis 20020201

• Treatment of thalassoemia--the current scenario.

  Journal of the Indian Medical Association 20020201

• Transcriptional silencing and developmental reactivation of cry1Ab gene in transgenic rice.

  Science in China. Series C, Life sciences 20020201

• Bone marrow-derived regenerated cardiomyocytes (CMG Cells) express functional adrenergic and muscarinic receptors.

  Circulation 20020122

• Aberrant methylation and histone deacetylation of cyclooxygenase 2 in gastric cancer.

  International journal of cancer 20020120

• Characterization of XAGE-1b, a short major transcript of cancer/testis-associated gene XAGE-1, induced in melanoma metastasis.

  International journal of cancer 20020110

• DNA methylation regulates the expression of Y chromosome specific genes in prostate cancer.

  The Journal of urology 20020101

• Specific patterns of gene methylation in natural killer cell lymphomas : p73 is consistently involved.

  The American journal of pathology 20020101

• Novel agents for the therapy of acute leukemia.

  Current opinion in oncology 20020101

• Primary acute myeloid leukaemia blasts resistant to cytokine-induced differentiation to dendritic-like leukaemia cells can be forced to differentiate by the addition of bryostatin-1.

  Leukemia 20020101

• The opposed effect of 5-azacytidine and light on the development of reproductive structures in Neurospora crassa.

  Photochemistry and photobiology 20020101

• Sequential observations of exencephaly and subsequent morphological changes by mouse exo utero development system: analysis of the mechanism of transformation from exencephaly to anencephaly.

  Anatomy and embryology 20020101

• De novo expression of the Muc2 gene in pancreas carcinoma cells is triggered by promoter demethylation.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20020101

• Promoter methylation controls the expression of MAGE2, 3 and 4 genes in human cutaneous melanoma.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20020101

• New approaches to the treatment of myelodysplasia.

  The oncologist 20020101

• Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells.

  Methods in enzymology 20020101

• Expression spectrum and methylation-dependent regulation of melanoma antigen-encoding gene family members in pancreatic cancer cells.

  Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101

• Expression of ribosomal protein L4 (rpL4) during neurogenesis and 5-azacytidine (5AzC)-induced apoptotic process in the rat.

  Histology and histopathology 20020101

• Methylation state of the prostate specific membrane antigen (PSMA) CpG island in prostate cancer cell lines.

  Anticancer research 20020101

• [Effect of 5-azacytidine on expression of DNA sequences homologous to ENV gene of murine mammary tumor virus in normal human lymphocytes].

  Molekuliarnaia genetika, mikrobiologiia i virusologiia 20020101

• Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays.

  Genome biology 20020101

• MYEOV, a gene at 11q13, is coamplified with CCND1, but epigenetically inactivated in a subset of esophageal squamous cell carcinomas.

  Journal of human genetics 20020101

• Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation.

  Molecular cancer 20020101

• Cyclin D2 expression in familial and sporadic breast cancer.

  Oncology reports 20020101

• [Telomerase: an enzyme with multiple applications in cancer research].

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20020101

• Aberrant methylation of the 5' CpG island of TSLC1 is common in pancreatic ductal adenocarcinoma and is first manifest in high-grade PanlNs.

  Cancer biology & therapy 20020101

• Characteristic promoter hypermethylation signatures in male germ cell tumors.

  Molecular cancer 20020101

• 5-aza-2'-deoxycytidine induces retinoic acid receptor beta 2 demethylation, cell cycle arrest and growth inhibition in breast carcinoma cells.

  Anticancer research 20020101

• A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers.

  Anticancer research 20020101

• Roles of histone acetylation in the Dnmt1 gene expression.

  Nucleic acids research. Supplement (2001) 20020101

• Azacitidine.

  Report on carcinogens : carcinogen profiles 20020101

• DNA methylation of the human oxytocin receptor gene promoter regulates tissue-specific gene suppression.

  Biochemical and biophysical research communications 20011207

• Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma.

  Cancer research 20011201

• Potential of 5-aza-2'-deoxycytidine (Decitabine) a potent inhibitor of DNA methylation for therapy of advanced non-small cell lung cancer.

  Lung cancer (Amsterdam, Netherlands) 20011201

• Reexpression of a cluster of silenced transgenes is associated with their rearrangement.

  Genes, chromosomes & cancer 20011201

• Expression of the Hypermethylated in Cancer gene (HIC-1) is associated with good outcome in human breast cancer.

  British journal of cancer 20011201

• [Chemotherapy and radiation therapy].

  Nihon rinsho. Japanese journal of clinical medicine 20011201

• MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers.

  Journal of cancer research and clinical oncology 20011201

• Differential esterase expression in developmental mutants of Aspergillus nidulans.

  Biochemical genetics 20011201

• DNA from Aspergillus flavus contains 5-methylcytosine.

  FEMS microbiology letters 20011127

• Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.

  Oncogene 20011122

• Hypermethylation in human cancers of the RIZ1 tumor suppressor gene, a member of a histone/protein methyltransferase superfamily.

  Cancer research 20011115

• Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.

  Cancer research 20011115

• 5-Aza-2'-deoxycytidine induces histone hyperacetylation of mouse centromeric heterochromatin by a mechanism independent of DNA demethylation.

  Biochemical and biophysical research communications 20011109

• E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells.

  Cancer letters 20011108

• RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours.

  Oncogene 20011108

• Early detection of endogenous retroviruses in chemically induced mouse cells.

  Virus research 20011105

• Inhibition of histone deacetylase activity causes cell type-specific induction of the PDGF-B promoter only in the absence of activation by its enhancer.

  Experimental cell research 20011101

• Diminished expression of S100A2, a putative tumor suppressor, at early stage of human lung carcinogenesis.

  Cancer research 20011101

• CpG methylation as a basis for breast tumor-specific loss of NES1/kallikrein 10 expression.

  Cancer research 20011101

• GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells.

  The American journal of pathology 20011101

• Glypican-3 expression is silenced in human breast cancer.

  Oncogene 20011101

• Reduced expression of intercellular adhesion molecule-1 in ovarian adenocarcinomas.

  British journal of cancer 20011101

• Methylation of episomal plasmids as a barrier to transient gene expression via a synthetic delivery vector.

  Biomolecular engineering 20011031

• Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.

  The Journal of biological chemistry 20011026

• Methylation in hMLH1 promoter interferes with its binding to transcription factor CBF and inhibits gene expression.

  Oncogene 20011025

• Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation.

  European journal of pharmacology 20011019

• CpG hypermethylation of the promoter region inactivates the estrogen receptor-beta gene in patients with prostate carcinoma.

  Cancer 20011015

• Methylation changes in the human IGF2 p3 promoter parallel IGF2 expression in the primary tumor, established cell line, and xenograft of a human hepatoblastoma.

  Experimental cell research 20011015

• Rexpression of HLA class I antigens and restoration of antigen-specific CTL response in melanoma cells following 5-aza-2'-deoxycytidine treatment.

  International journal of cancer 20011015

• DNA hypomethylation of karyoplasts for bovine nuclear transplantation.

  Molecular reproduction and development 20011001

• DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas.

  Carcinogenesis 20011001

• Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.

  Cancer research 20011001

• Chondrocyte phenotype and cell survival are regulated by culture conditions and by specific cytokines through the expression of Sox-9 transcription factor.

  Rheumatology (Oxford, England) 20011001

• Reduced expression of syndecan-1 affects metastatic potential and clinical outcome in patients with colorectal cancer.

  Japanese journal of cancer research : Gann 20011001

• Pharmacological reactivation of inactive genes: the fragile X experience.

  Brain research bulletin 20011001

• 5-azacytidine induces chromosomal breakage in the root tips of wheat carrying the cuckoo chromosome 4S(L) from Aegilops sharonensis.

  Heredity 20011001

• Brain from bone: efficient 'meta-differentiation' of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent.

  Differentiation; research in biological diversity 20011001

• Histone deacetylase and DNA methyltransferase in human prostate cancer.

  Biochemical and biophysical research communications 20010928

• Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer.

  Oncogene 20010913

• The E-cadherin gene is silenced by CpG methylation in human oral squamous cell carcinomas.

  International journal of cancer 20010901

• Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma.

  International journal of cancer 20010901

• Loss of annexin II heavy and light chains in prostate cancer and its precursors.

  Cancer research 20010901

• Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells.

  British journal of cancer 20010901

• CpG methylation of promoter region inactivates E-cadherin gene in renal cell carcinoma.

  Molecular carcinogenesis 20010901

• Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma.

  Molecular carcinogenesis 20010901

• Epigenetic regulation of the KAI1 metastasis suppressor gene in human prostate cancer cell lines.

  Japanese journal of cancer research : Gann 20010901

• Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription.

  Molecular cell 20010901

• Selection of drug-resistant transduced cells with cytosine nucleoside analogs using the human cytidine deaminase gene.

  Cancer gene therapy 20010901

• Alteration of DNA methylation in gastrointestinal carcinogenesis.

  Journal of gastroenterology and hepatology 20010901

• Evolving treatment options of myelodysplastic syndromes.

  Annals of hematology 20010901

• 5-azaC treatment enhances expression of transforming growth factor-beta receptors through down-regulation of Sp3.

  The Journal of biological chemistry 20010831

• Molecular mechanisms for aberrant expression of the human breast cancer specific gene 1 in breast cancer cells: control of transcription by DNA methylation and intronic sequences.

  Oncogene 20010823

• Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2.

  Cancer research 20010815

• Loss of cyp1a1 messenger rna expression due to nonsense-mediated decay.

  Molecular pharmacology 20010801

• DNA methylation regulates placental lactogen I gene expression.

  Endocrinology 20010801

• Activation of the maternally preset program of apoptosis by microinjection of 5-aza-2'-deoxycytidine and 5-methyl-2'-deoxycytidine-5'-triphosphate in Xenopus laevis embryos.

  Development, growth & differentiation 20010801

• Cytogenetic responses in high-risk myelodysplastic syndrome following low-dose treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine.

  British journal of haematology 20010801

• Inactivation of retinoic acid receptor beta by promoter CpG hypermethylation in gastric cancer.

  Differentiation; research in biological diversity 20010801

• Regulation of the intestinal mucin MUC2 gene expression in vivo: evidence for the role of promoter methylation.

  Cancer letters 20010710

• Evidence for gene silencing in Haemophilus influenzae.

  Mutation research 20010701

• Promoter hypermethylation: a common cause of reduced p16(INK4a) expression in uveal melanoma.

  Cancer research 20010701

• Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures.

  Haematologica 20010701

• Loss of mismatch repair activity in simian virus 40 large T antigen-immortalized BPH-1 human prostatic epithelial cell line.

  Molecular carcinogenesis 20010701

• Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells.

  Cancer chemotherapy and pharmacology 20010701

• Cytosine methylation represses glutathione S-transferase P1 (GSTP1) gene expression in human prostate cancer cells.

  Cancer research 20010615

• Increased sensitivity of transforming growth factor (TGF) beta 1 null cells to alkylating agents reveals a novel link between TGFbeta signaling and O(6)-methylguanine methyltransferase promoter hypermethylation.

  The Journal of biological chemistry 20010601

• Transcriptional silencing of Cyclooxygenase-2 by hyper-methylation of the 5' CpG island in human gastric carcinoma cells.

  Cancer research 20010601

• DNA methylation inhibits expression and transposition of the Neurospora Tad retrotransposon.

  Molecular genetics and genomics : MGG 20010601

• Overexpression of MnSOD protects murine fibrosarcoma cells (FSa-II) from apoptosis and promotes a differentiation program upon treatment with 5-azacytidine: involvement of MAPK and NFkappaB pathways.

  Antioxidants & redox signaling 20010601

• Decitabine with allogeneic peripheral blood stem cell transplantation in the therapy of leukemia relapse following a prior transplant: results of a phase I study.

  Bone marrow transplantation 20010601

• Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer.

  Cancer research 20010515

• Induction of Tax i expression in MT-4 cells by 5-azacytidine leads to protein binding in the HTLV-1 LTR in vivo.

  Virology 20010510

• Advances in experimental treatment of beta-thalassaemia.

  Expert opinion on investigational drugs 20010501

• 5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.

  Cancer research 20010501

• Two-dimensional database of a Burkitt lymphoma cell line (DG 75) proteins: protein pattern changes following treatment with 5'-azycytidine.

  Electrophoresis 20010501

• Effects of simian virus 40 T-antigens on normal human mammary epithelial cells reveal evidence for spontaneous alterations in addition to loss of p16(INK4a) expression.

  Experimental cell research 20010415

• Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications.

  Annals of internal medicine 20010403

• Maedi-visna virus, a model for in vitro testing of potential anti-HIV drugs.

  Comparative immunology, microbiology and infectious diseases 20010401

• Activation of the p53 DNA damage response pathway after inhibition of DNA methyltransferase by 5-aza-2'-deoxycytidine.

  Molecular pharmacology 20010401

• Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene MGMT.

  International journal of cancer 20010401

• Association of acetylated histones with paternally expressed genes in the Prader--Willi deletion region.

  Human molecular genetics 20010315

• Association of deletions and translocation of the reduced folate carrier gene with profound loss of gene expression in methotrexate-resistant K562 human erythroleukemia cells.

  Biochemical pharmacology 20010315

• Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells.

  Cancer research 20010315

• Telomerase activity is repressed during differentiation along the hepatocytic and biliary epithelial lineages: verification on immortal cell lines from the same origin.

  Cell biochemistry and function 20010301

• Pharmacologic induction of fetal hemoglobin: raising the therapeutic bar in sickle cell disease.

  Current opinion in hematology 20010301

• Sequence of centromere separation: effect of 5-azacytidine-induced epigenetic alteration.

  Mutagenesis 20010301

• Analysis of the ANA gene as a candidate for the chromosome 21q oral cancer susceptibility locus.

  British journal of cancer 20010301

• Silencing of the caspase-1 gene occurs in murine and human renal cancer cells and causes solid tumor growth in vivo.

  International journal of cancer 20010301

• Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.

  Cancer research 20010301

• Development of regenerative cardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering.

  Artificial organs 20010301

• Evidence of abundant constitutive alkali-labile sites in human 5 bp classical satellite DNA loci by DBD-FISH.

  Mutation research 20010220

• Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

  Cancer research 20010215

• DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors.

  Cancer research 20010215

• Unbalanced expression of HLA-A and -B antigens: a specific feature of cutaneous melanoma and other non-hemopoietic malignancies reverted by IFN-gamma.

  International journal of cancer 20010215

• Effect of 5-Aza-2'-deoxycytidine on the P16 tumor suppressor gene in hepatocellular carcinoma cell line HepG2.

  World journal of gastroenterology 20010215

• Effects of hydroxurea, stem cell factor, and erythropoietin in combination on fetal hemoglobin in the baboon.

  Experimental hematology 20010201

• Sensitization by 5-aza-2'-deoxycytidine of leukaemia cells with MLL abnormalities to induction of differentiation by all-trans retinoic acid and 1alpha,25-dihydroxyvitamin D3.

  British journal of haematology 20010201

• A novel cell culture model of chondrocyte differentiation during mammalian endochondral ossification.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010201

• Identification of a novel member of the snail/Gfi-1 repressor family, mlt 1, which is methylated and silenced in liver tumors of SV40 T antigen transgenic mice.

  Cancer research 20010201

• Rhesus monkey model for fetal gene transfer: studies with retroviral- based vector systems.

  Molecular therapy : the journal of the American Society of Gene Therapy 20010201

• Evidence that silencing of the HPRT promoter by DNA methylation is mediated by critical CpG sites.

  The Journal of biological chemistry 20010105

• Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer.

  The American journal of pathology 20010101

• Lack of telomerase RNA gene hTERC expression in alternative lengthening of telomeres cells is associated with methylation of the hTERC promoter.

  Cancer research 20010101

• Induction of MAGE-3 expression in lung and esophageal cancer cells.

  The Annals of thoracic surgery 20010101

• Anticancer drug-induced kidney disorders.

  Drug safety 20010101

• DNA methylation contributes to tissue- and allele-specific expression of the T-cell differentiation marker RT6.

  Immunogenetics 20010101

• Transcripts of the MHM region on the chicken Z chromosome accumulate as non-coding RNA in the nucleus of female cells adjacent to the DMRT1 locus.

  Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20010101

• [Effect of inhibitors of enzymatic DNA methylation on the formation of reproductive structures and carotenoid production in Neurospora crassa].

  Prikladnaia biokhimiia i mikrobiologiia 20010101

• 5-Azacytidine modulates the response of sensitive and multidrug-resistant K562 leukemic cells to cytostatic drugs.

  Blood cells, molecules & diseases 20010101

• Autoreactive murine Th1 and Th2 cells kill syngeneic macrophages and induce autoantibodies.

  Lupus 20010101

• 6-azacytidine--compound with wide spectrum of antiviral activity.

  Nucleosides, nucleotides & nucleic acids 20010101

• Zidovudine (AZT) resistance in H9 cells due to decreased TK expression is associated with hypermethylation of TK gene.

  Nucleosides, nucleotides & nucleic acids 20010101

• Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties.

  Nucleosides, nucleotides & nucleic acids 20010101

• Demethylation by 5-aza-2'-deoxycytidine (5-azadC) of p16INK4A gene results in downregulation of vascular endothelial growth factor expression in human lung cancer cell lines.

  Oncology research 20010101

• Evaluation of pharmacological induction of fatty acid beta-oxidation in X-linked adrenoleukodystrophy.

  Molecular genetics and metabolism 20010101

• Altered hox gene expression and cellular pathogenesis of 5-aza-2'-deoxycytidine-induced murine hindlimb dysmorphogenesis.

  Toxicologic pathology 20010101

• Hematologic malignancies: an opportunity for targeted drug therapy.

  The oncologist 20010101

• Targeting hypomethylation of DNA to achieve cellular differentiation in myelodysplastic syndromes (MDS).

  The oncologist 20010101

• The involvement of photoregulated DNA methylation into a choice between sexual and asexual developmental pathways in Neurospora crassa.

  Doklady. Biochemistry and biophysics 20010101

• Genetic and cytological characterization of a developmental mutant of Aspergillus nidulans induced by 5-azacytidine.

  Biological research 20010101

• Induction/activation and detection of occult viral agents present in mammalian cells.

  Developments in biologicals 20010101

• [Sensitivity of E. coli and C. freundii strains to 5-azacytidine].

  Voprosy meditsinskoi khimii 20010101

• Pharmacologic induction of fetal hemoglobin synthesis: cellular and molecular mechanisms.

  Pediatric pathology & molecular medicine 20010101

• Unnatural enantiomers of 5-azacytidine analogues: syntheses and enzymatic properties.

  European journal of medicinal chemistry 20001101

• Comparative effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on MCF-7, RL95-2, and LNCaP cells: role of target steroid hormones in cellular responsiveness to CYP1A1 induction.

  Molecular cell biology research communications : MCBRC 20000901

• Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B.

  Cancer 19980415

• Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B.

  Cancer 19970601

• Pilot phase I-II study on 5-aza-2'-deoxycytidine (Decitabine) in patients with metastatic lung cancer.

  Anti-cancer drugs 19970401

• Inhibition of sandfly fever Sicilian virus (Phlebovirus) replication in vitro by antiviral compounds.

  Research in virology 19970101

• Rhabdomyolysis: an unusual complication of cytotoxic chemotherapy.

  Medical oncology (Northwood, London, England) 19951201

• Effect of 5-azacytidine on expression of the human DNA repair enzyme O6-methylguanine-DNA methyltransferase.

  Carcinogenesis 19940401

• Antiproliferative effects and DNA hypomethylation by 5-aza-2'-deoxycytidine in human neuroblastoma cell lines.

  Anti-cancer drugs 19931201

• A phase II study of 5,6-dihydro-5-azacytidine hydrochloride in disseminated malignant melanoma.

  American journal of clinical oncology 19930601

• Increased sensitivity of nontumorigenic fibroblasts expressing ras or myc oncogenes to malignant transformation induced by 5-aza-2'-deoxycytidine.

  Cancer research 19910101

• Comparative activities of several nucleoside analogs against duck hepatitis B virus in vitro.

  Antimicrobial agents and chemotherapy 19900701

• Comparison of the incidence of 5-azacytidine-induced exencephaly between MT/HokIdr and Slc:ICR mice.

  Teratology 19900201

• 5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitro.

  Antimicrobial agents and chemotherapy 19900201

• Histological study of cell death in digital malformations induced by 5-azacytidine: suppressive effect of caffeine.

  Teratology 19890201

• Increased metallothionein gene expression in 5-aza-2'-deoxycytidine-induced resistance to cadmium cytotoxicity.

  Chemico-biological interactions 19880101

• Fetal hemoglobin gene activation in a phase II study of 5,6-dihydro-5-azacytidine for bronchogenic carcinoma.

  Cancer research 19870801

• Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.

  Biochemical pharmacology 19860701

• Diaplacental carcinogenic effects of 5-azacytidine in NMRI-mice.

  Cancer letters 19850501

• Sequentially administered 5-azacitidine and amsacrine in refractory adult acute leukemia: a phase I-II trial of the Southeastern Cancer Study Group.

  Cancer treatment reports 19850101

• 5-azacytidine potentiates initiation induced by carcinogens in rat liver.

  Carcinogenesis 19850101

• The tumorigenicity of 5-azacytidine in the male Fischer rat.

  Carcinogenesis 19841201

• Is there more than one critical lesion relevant for experimental liver carcinogenesis?

  Toxicologic pathology 19840101

• Developmental activation of the H-2K gene is correlated with an increase in DNA methylation.

  Cell 19831201

• 5-azacytidine in refractory acute leukemia.

  Oncology 19820101

• 5-Azacytidine and renal tubular dysfunction.

  Blood 19810101

• Cellular differentiation, cytidine analogs and DNA methylation.

  Cell 19800501

• Morphological correlates of behavioral abnormalities in experimental congenital brain damage.

  Experimental neurology 19771001

• Biological effects of 5-azacytidine in eukaryotes.

  Oncology 19740101