321-14-2 | 5-Chlorosalicylic acid

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$22.00	$15.00
100g	98%	in stock	$25.00	$17.00
1kg	98%	in stock	$175.00	$122.00
5kg	98%	in stock	$622.00	$435.00
10kg	98%	in stock	$1,148.00	$803.00

Description

• Catalog Number: AB49323
• Chemical Name: 5-Chlorosalicylic acid
• CAS Number: 321-14-2
• Molecular Formula: C7H5ClO3
• Molecular Weight: 172.5658
• MDL Number: MFCD00002457
• SMILES: Clc1ccc(c(c1)C(=O)O)O
• NSC Number: 30111

Computed Properties

• Complexity: 160
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 3.1

Literature

• Effect of biological confinement on the photophysics and dynamics of a proton-transfer phototautomer: an exploration of excitation and emission wavelength-dependent photophysics of the protein-bound drug.

  Physical chemistry chemical physics : PCCP 20120921

• Antimicrobial activity of sulfonamides containing 5-chloro-2-hydroxybenzaldehyde and 5-chloro-2-hydroxybenzoic acid scaffold.

  European journal of medicinal chemistry 20120401

• Two centrosymmetric dinuclear phenanthroline-copper(II) complexes with 3,5-dichloro-2-hydroxybenzoic acid and 5-chloro-2-hydroxybenzoic acid.

  Acta crystallographica. Section C, Crystal structure communications 20120401

• Structure-activity relationship of salicylic acid derivatives on inhibition of TNF-α dependent NFκB activity: Implication on anti-inflammatory effect of N-(5-chlorosalicyloyl)phenethylamine against experimental colitis.

  European journal of medicinal chemistry 20120201

• Fluorescence-based high-throughput screening assay for drug interactions with UGT1A6.

  Assay and drug development technologies 20111001

• Structural, vibrational and quantum chemical investigations on 5-chloro-2-hydroxybenzamide and 5-chloro-2-hydroxybenzoic acid.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901

• SA-ABA antagonism in defense responses.

  Plant signaling & behavior 20101001

• catena-Poly[[(1,10-phenanthroline)lead(II)]bis-(μ-5-chloro-2-hy-droxy-benzoato)].

  Acta crystallographica. Section E, Structure reports online 20100801

• Bismuth(III) complexes derived from non-steroidal anti-inflammatory drugs and their activity against Helicobacter pylori.

  Dalton transactions (Cambridge, England : 2003) 20100321

• Deciphering the photophysics of 5-chlorosalicylic acid: evidence for excited-state intramolecular proton transfer.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100101

• Novel metal-binding site of Pseudomonas reinekei MT1 trans-dienelactone hydrolase.

  Biochemical and biophysical research communications 20091225

• trans-Dienelactone hydrolase from Pseudomonas reinekei MT1, a novel zinc-dependent hydrolase.

  Biochemical and biophysical research communications 20081114

• In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.

  Bioorganic & medicinal chemistry 20081015

• Transport evaluation of salicylic acid and structurally related compounds across Caco-2 cell monolayers and artificial PAMPA membranes.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

• Bis(5-chloro-salicylato-κO)bis-(1,10-phenanthroline-κN,N')cadmium(II).

  Acta crystallographica. Section E, Structure reports online 20080701

• Salicylate activity. 1. Protection of plants from paraquat injury.

  Journal of agricultural and food chemistry 20051214

• Salicylate activity. 3. Structure relationship to systemic acquired resistance.

  Journal of agricultural and food chemistry 20051214

• Guest-controlling effects on ER behaviors of beta-cyclodextrin polymer.

  Journal of colloid and interface science 20050901

• Predicting human serum albumin affinity of interleukin-8 (CXCL8) inhibitors by 3D-QSPR approach.

  Journal of medicinal chemistry 20050407

• Anaerobic degradation and dehalogenation of chlorosalicylates and salicylate under four reducing conditions.

  Biodegradation 20010101