3211-76-5 | L-selenomethionine

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$15.00	$10.00
100mg	98%	in stock	$22.00	$15.00
250mg	98%	in stock	$39.00	$27.00
1g	98%	in stock	$93.00	$65.00
5g	98%	in stock	$269.00	$188.00
25g	98%	in stock	$890.00	$623.00

Description

• Catalog Number: AB50209
• Chemical Name: L-selenomethionine
• CAS Number: 3211-76-5
• Molecular Formula: C5H11NO2Se
• Molecular Weight: 196.1063
• MDL Number: MFCD00037210
• SMILES: C[Se]CC[C@@H](C(=O)O)N
• NSC Number: 760370

Computed Properties

• Complexity: 97
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Literature

• Cardiac and Metabolic Effects of Dietary Selenomethionine Exposure in Adult Zebrafish.

  Toxicological sciences : an official journal of the Society of Toxicology 20171001

• Superoxide-hydrogen peroxide genetic imbalance modulates differentially the oxidative metabolism on human peripheral blood mononuclear cells exposed to seleno-L-methionine.

  Chemico-biological interactions 20170801

• Effect of selenomethionine supplementation in food on the excretion and toxicity of arsenic exposure in female mice.

  Biological trace element research 20131201

• Molecular mechanisms involved in the protective effect of selenocystine against methylmercury-induced cell death in human HepG2 cells.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901

• Effects of chronic dietary selenomethionine exposure on repeat swimming performance, aerobic metabolism and methionine catabolism in adult zebrafish (Danio rerio).

  Aquatic toxicology (Amsterdam, Netherlands) 20130415

• Haemostatic effects of levothyroxine and selenomethionine in euthyroid patients with Hashimoto's thyroiditis.

  Thrombosis and haemostasis 20121101

• Monitoring the production process of selenized yeast by elemental speciation analysis.

  Metallomics : integrated biometal science 20121101

• A reliable solid phase microextraction-gas chromatography-triple quadrupole mass spectrometry method for the assay of selenomethionine and selenomethylselenocysteine in aqueous extracts: difference between selenized and not-enriched selenium potatoes.

  Analytica chimica acta 20121017

• Forms of selenium affect its transport, uptake and glutathione peroxidase activity in the Caco-2 cell model.

  Biological trace element research 20121001

• Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation.

  Journal of the American Chemical Society 20120912

• Major differences among chemopreventive organoselenocompounds in the sustained elevation of cytoprotective genes.

  Journal of biochemical and molecular toxicology 20120901

• Selenium blocks porcine circovirus type 2 replication promotion induced by oxidative stress by improving GPx1 expression.

  Free radical biology & medicine 20120801

• Bis-pentafluorobenzyl derivatives of N-acetyl-L-methionine and N-acetyl-L-selenomethionine for the quantitative determination in human plasma by gas chromatography-negative ion chemical ionisation mass spectrometry.

  Journal of chromatography. A 20120615

• Induction of oxidative stress by selenomethionine in isolated hepatocytes of rainbow trout (Oncorhynchus mykiss).

  Toxicology in vitro : an international journal published in association with BIBRA 20120601

• Differential responses to selenomethionine supplementation by sex and genotype in healthy adults.

  The British journal of nutrition 20120501

• Lysophosphatidic acid causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells.

  Atherosclerosis 20120501

• Application of amino acid amides as chiral auxiliaries in difluoro dinitro benzene and cyanuric chloride moieties for high-performance liquid-chromatographic enantioseparation of selenomethionine and its mixture with methionine and cysteine.

  Amino acids 20120401

• Validated high-performance liquid chromatographic enantioseparation of selenomethionine using isothiocyanate based chiral derivatizing reagents.

  Biomedical chromatography : BMC 20120401

• Effect of selenium sources on the expression of cellular glutathione peroxidase and cytoplasmic thioredoxin reductase in the liver and kidney of broiler breeders and their offspring.

  Poultry science 20120401

• Cytotoxic mechanism of selenomethionine in yeast.

  The Journal of biological chemistry 20120323

• Effects of organic selenium supplementation on growth performance, carcass measurements, tissue selenium concentrations, characteristics of reproductive organs, and testis gene expression profiles in boars.

  Journal of animal science 20120201

• Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells.

  Free radical research 20120201

• Effects of salinity on the toxicity and biotransformation of L-selenomethionine in Japanese medaka (Oryzias latipes) embryos: mechanisms of oxidative stress.

  Aquatic toxicology (Amsterdam, Netherlands) 20120201

• Inward facing conformations of the MetNI methionine ABC transporter: Implications for the mechanism of transinhibition.

  Protein science : a publication of the Protein Society 20120101

• Selenium toxicity to honey bee (Apis mellifera L.) pollinators: effects on behaviors and survival.

  PloS one 20120101

• Analysis of selenomethylselenocysteine and selenomethionine by LC-ESI-MS/MS with diethyl ethoxymethylenemalonate derivatization.

  The Analyst 20111221

• Catalytic activity of selenomethionine in removing amino acid, peptide, and protein hydroperoxides.

  Free radical biology & medicine 20111215

• Influence of dietary selenomethionine supplementation on performance and selenium status of broiler breeders and their subsequent progeny.

  Biological trace element research 20111201

• Effects of dietary form of selenium on its distribution in eggs.

  Biological trace element research 20111201

• Effects of antioxidant supplementation on duodenal Se-Met absorption in ethanol-exposed rat offspring in vivo.

  The Journal of reproduction and development 20111201

• Use of stringent selection parameters for the identification of possible selenium-responsive marker genes in mouse liver and gastrocnemius.

  Biological trace element research 20111101

• Simultaneous determination of selenomethionine enantiomers in biological fluids by stable isotope dilution gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101

• Optimized procedure to generate heavy isotope and selenomethionine-labeled proteins for structure determination using Escherichia coli-based expression systems.

  Applied microbiology and biotechnology 20111101

• Comparison of different forms of dietary selenium supplementation on growth performance, meat quality, selenium deposition, and antioxidant property in broilers.

  Biological trace element research 20111001

• Evaluating the trophic transfer of selenium in aquatic ecosystems using caged fish, X-ray absorption spectroscopy and stable isotope analysis.

  Ecotoxicology and environmental safety 20111001

• Chronic exposure to dietary selenomethionine increases gonadal steroidogenesis in female rainbow trout.

  Aquatic toxicology (Amsterdam, Netherlands) 20111001

• Selenium bioaccumulation and speciation in Chironomus dilutus exposed to water-borne selenate, selenite, or seleno-DL-methionine.

  Environmental toxicology and chemistry 20111001

• Absorption and retention characteristics of selenium in dorsal root ganglion neurons.

  Metallomics : integrated biometal science 20111001

• Attenuation of the cortisol response to stress in female rainbow trout chronically exposed to dietary selenomethionine.

  Aquatic toxicology (Amsterdam, Netherlands) 20111001

• Effect of different selenium sources on productive performance, serum and milk Se concentrations, and antioxidant status of sows.

  Biological trace element research 20110901

• Selenomethionine: an effective selenium source for sow to improve Se distribution, antioxidant status, and growth performance of pig offspring.

  Biological trace element research 20110901

• Distribution of Se and its species in Myriophyllum spicatum and Ceratophyllum demersum growing in water containing Se (VI).

  Chemosphere 20110901

• In vitro and in vivo percutaneous absorption of seleno-L-methionine, an antioxidant agent, and other selenium species.

  Acta pharmacologica Sinica 20110901

• A novel cystine based antioxidant attenuates oxidative stress and hepatic steatosis in diet-induced obese mice.

  Experimental and molecular pathology 20110801

• The effect of levothyroxine and selenomethionine on lymphocyte and monocyte cytokine release in women with Hashimoto's thyroiditis.

  The Journal of clinical endocrinology and metabolism 20110701

• Induction of ROS, p53, p21 in DEHP- and MEHP-exposed LNCaP cells-protection by selenium compounds.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

• Effect of sample preparation methods on the D,L-enantiomer ratio of extracted selenomethionine.

  Analytical and bioanalytical chemistry 20110701

• Reduction of cisplatin-induced nephrotoxicity in vivo by selenomethionine: the effect on cisplatin-DNA adducts.

  Chemical research in toxicology 20110620

• Species-specific sensitivity to selenium-induced impairment of cortisol secretion in adrenocortical cells of rainbow trout (Oncorhynchus mykiss) and brook trout (Salvelinus fontinalis).

  Toxicology and applied pharmacology 20110601

• DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein.

  The Journal of biological chemistry 20110513

• Anti-hemolytic and peroxyl radical scavenging activity of organoselenium compounds: an in vitro study.

  Biological trace element research 20110501

• Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells.

  Cancer chemotherapy and pharmacology 20110501

• Preventing metal-mediated oxidative DNA damage with selenium compounds.

  Metallomics : integrated biometal science 20110501

• Selenium effects on arsenic cytotoxicity and protein phosphorylation in human kidney cells using chip-based nanoLC-MS/MS.

  Metallomics : integrated biometal science 20110501

• Additional phase information from UV damage of selenomethionine labelled proteins.

  Journal of synchrotron radiation 20110501

• Uptake, distribution, and speciation of selenoamino acids by human cancer cells: X-ray absorption and fluorescence methods.

  Biochemistry 20110315

• Dietary selenomethionine exposure in adult zebrafish alters swimming performance, energetics and the physiological stress response.

  Aquatic toxicology (Amsterdam, Netherlands) 20110301

• Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes.

  Osteoarthritis and cartilage 20110101

• Selenomethionine increases proliferation and reduces apoptosis in bovine mammary epithelial cells under oxidative stress.

  Journal of dairy science 20110101

• Mouse prostate proteomes are differentially altered by supranutritional intake of four selenium compounds.

  Nutrition and cancer 20110101

• [Effects of organic selenium substance, selenomethionine, in acute alcohol intoxication].

  Biomeditsinskaia khimiia 20110101

• Selenomethionine incorporation into amyloid sequences regulates fibrillogenesis and toxicity.

  PloS one 20110101

• Crystallization and preliminary X-ray data collection of the Escherichia coli lipoproteins BamC, BamD and BamE.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20101201

• Improving the diffraction of full-length human selenomethionyl metavinculin crystals by streak-seeding.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20101201

• Crystallization and preliminary diffraction analysis of Wzi, a member of the capsule export and assembly pathway in Escherichia coli.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20101201

• Synthesis of D- and L-selenomethionine double-labeled with deuterium and selenium-82.

  Chemical & pharmaceutical bulletin 20101201

• Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium.

  Toxicology and applied pharmacology 20101001

• Simultaneous analysis of mercury and selenium species including chiral forms of selenomethionine in human urine and serum by HPLC column-switching coupled to ICP-MS.

  The Analyst 20101001

• Mapping of selenium metabolic pathway in yeast by liquid chromatography-Orbitrap mass spectrometry.

  Analytical chemistry 20101001

• A rapid and sensitive CE method with field-enhanced sample injection and in-capillary derivatization for selenomethionine metabolism catalyzed by flavin-containing monooxygenases.

  Electrophoresis 20101001

• Effects of a novel cystine-based glutathione precursor on oxidative stress in vascular smooth muscle cells.

  American journal of physiology. Cell physiology 20100901

• Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells.

  Free radical biology & medicine 20100815

• Crystal structure of exotype alginate lyase Atu3025 from Agrobacterium tumefaciens.

  The Journal of biological chemistry 20100806

• Seleno L-methionine acts on cyclophosphamide-induced kidney toxicity.

  Biological trace element research 20100801

• Differential apoptotic response of human cancer cells to organoselenium compounds.

  Cancer chemotherapy and pharmacology 20100801

• Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model.

  Cancer prevention research (Philadelphia, Pa.) 20100801

• Chemical demethylation of methylmercury by selenoamino acids.

  Chemical research in toxicology 20100719

• Interventions for clinical and subclinical hypothyroidism in pregnancy.

  The Cochrane database of systematic reviews 20100707

• Serum cytokine analysis in a positive chemoprevention trial: selenium, interleukin-2, and an association with squamous preneoplastic disease.

  Cancer prevention research (Philadelphia, Pa.) 20100701

• Omp85 from the thermophilic cyanobacterium Thermosynechococcus elongatus differs from proteobacterial Omp85 in structure and domain composition.

  The Journal of biological chemistry 20100604

• Comparison of selenohomolanthionine and selenomethionine in terms of selenium distribution and toxicity in rats by bolus administration.

  Metallomics : integrated biometal science 20100601

• Antioxidant capacity of Macaronesian traditional medicinal plants.

  Molecules (Basel, Switzerland) 20100412

• Protective effect of seleno-L-methionine on cyclophosphamide-induced urinary bladder toxicity in rats.

  Biological trace element research 20100401

• AglP is a S-adenosyl-L-methionine-dependent methyltransferase that participates in the N-glycosylation pathway of Haloferax volcanii.

  Molecular microbiology 20100401

• Recombinant isotope labeled and selenium quantified proteins for absolute protein quantification.

  Analytical chemistry 20100315

• Null activity of selenium and vitamin e as cancer chemopreventive agents in the rat prostate.

  Cancer prevention research (Philadelphia, Pa.) 20100301

• Selenomethionine and alpha-tocopherol do not inhibit prostate carcinogenesis in the testosterone plus estradiol-treated NBL rat model.

  Cancer prevention research (Philadelphia, Pa.) 20100301

• Getting the best out of long-wavelength X-rays: de novo chlorine/sulfur SAD phasing of a structural protein from ATV.

  Acta crystallographica. Section D, Biological crystallography 20100301

• Antioxidant micronutrients and biomarkers of oxidative stress and inflammation in colorectal adenoma patients: results from a randomized, controlled clinical trial.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100301

• Effects of vitamin E and organic selenium on oxidative stability of omega-3 enriched dark chicken meat during cooking.

  Journal of food science 20100301

• Regulation of cellular glutathione peroxidase by different forms and concentrations of selenium in primary cultured bovine hepatocytes.

  The Journal of nutritional biochemistry 20100201

• Selenomethionine or methylseleninic acid inhibits mutagenesis of a reporter gene in mouse bone marrow.

  Anticancer research 20100201

• Competition between selenomethionine and methionine absorption in the intestinal tract of green sturgeon (Acipenser medirostris).

  Aquatic toxicology (Amsterdam, Netherlands) 20100121

• A systematic approach to the accurate quantification of selenium in serum selenoalbumin by HPLC-ICP-MS.

  Analytica chimica acta 20100111

• Cloning, expression, purification, crystallization and preliminary crystallographic studies of UgdG, an UDP-glucose dehydrogenase from Sphingomonas elodea ATCC 31461.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20100101

• Cell-free protein synthesis for structure determination by X-ray crystallography.

  Methods in molecular biology (Clifton, N.J.) 20100101

• The effects of selenium supplementation on the spontaneously occurring fibroid tumors of oviduct, 8-hydroxy-2'-deoxyguanosine levels, and heat shock protein 70 response in Japanese quail.

  Nutrition and cancer 20100101

• Crystallization and preliminary X-ray diffraction studies of FAD synthetase from Corynebacterium ammoniagenes.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20091201

• An improved HPLC method for the investigation of L-selenomethionine metabolism in rat gut contents.

  Biomedical chromatography : BMC 20091101

• Electrochemical oxidation of selenocystine and selenomethionine.

  Colloids and surfaces. B, Biointerfaces 20091101

• Speciation analysis of selenium metabolites in urine and breath by HPLC- and GC-inductively coupled plasma-MS after administration of selenomethionine and methylselenocysteine to rats.

  Chemical research in toxicology 20091101

• In vitro radioprotection studies of organoselenium compounds: differences between mono- and diselenides.

  Radiation and environmental biophysics 20091101

• Effects of dietary selenomethionine supplementation on growth performance, meat quality and antioxidant property in yellow broilers.

  Journal of agricultural and food chemistry 20091028

• X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.

  Journal of structural and functional genomics 20090901

• Lactosylceramide causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells.

  Medical science monitor : international medical journal of experimental and clinical research 20090901

• A description of the structural determination procedures of a gap junction channel at 3.5 A resolution.

  Acta crystallographica. Section D, Biological crystallography 20090801

• Structure of the C-terminal domain of nsp4 from feline coronavirus.

  Acta crystallographica. Section D, Biological crystallography 20090801

• Interpreting a low resolution map of human U1 snRNP using anomalous scatterers.

  Structure (London, England : 1993) 20090715

• Selenomethionine stimulates expression of glutathione peroxidase 1 and 3 and growth of bovine mammary epithelial cells in primary culture.

  Journal of dairy science 20090601

• Structure of the sporulation histidine kinase inhibitor Sda from Bacillus subtilis and insights into its solution state.

  Acta crystallographica. Section D, Biological crystallography 20090601

• Novel reactions of one-electron oxidized radicals of selenomethionine in comparison with methionine.

  The journal of physical chemistry. B 20090528

• Crystal structures of YkuI and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains.

  The Journal of biological chemistry 20090508

• Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction.

  Journal of mass spectrometry : JMS 20090501

• The effect of selenium, as selenomethionine, on genome stability and cytotoxicity in human lymphocytes measured using the cytokinesis-block micronucleus cytome assay.

  Mutagenesis 20090501

• Development of stable isotope and selenomethionine labeling methods for proteins expressed in Pseudomonas fluorescens.

  Protein expression and purification 20090501

• Methyl-selenium compounds inhibit prostate carcinogenesis in the transgenic adenocarcinoma of mouse prostate model with survival benefit.

  Cancer prevention research (Philadelphia, Pa.) 20090501

• The in vitro effects of selenomethionine on methylmercury-induced neurotoxicity.

  Toxicology in vitro : an international journal published in association with BIBRA 20090401

• Autoinduction of protein expression.

  Current protocols in protein science 20090401

• Enhancement of methyl methanesulfonate-induced base excision repair in the presence of selenomethionine on p53-dependent pathway.

  Journal of medicinal food 20090401

• Biodynamics, subcellular partitioning, and ultrastructural effects of organic selenium in a freshwater bivalve.

  Environmental science & technology 20090315

• Selenium and vitamin E: interesting biology and dashed hope.

  Journal of the National Cancer Institute 20090304

• Selenium and vitamin E: cell type- and intervention-specific tissue effects in prostate cancer.

  Journal of the National Cancer Institute 20090304

• The structure of the periplasmic thiol-disulfide oxidoreductase SoxS from Paracoccus pantotrophus indicates a triple Trx/Grx/DsbC functionality in chemotrophic sulfur oxidation.

  Acta crystallographica. Section D, Biological crystallography 20090301

• Expression, purification and crystallization of the cofactor-independent monooxygenase SnoaB from the nogalamycin biosynthetic pathway.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20090301

• Expression, purification and preliminary diffraction studies of CmlS.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20090301

• Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).

  JAMA 20090107

• Differential sensitivity of various human tumour-derived cell types to apoptosis by organic derivatives of selenium.

  The British journal of nutrition 20090101

• Reduction of L-methionine selenoxide to seleno-L-methionine by endogenous thiols, ascorbic acid, or methimazole.

  Biochemical pharmacology 20090101

• Facile synthesis and anti-tumor cell activity of Se-containing nucleosides.

  Nucleosides, nucleotides & nucleic acids 20090101

• Determination of selenomethionine by high-performance liquid chromatography-fluorescence detection coupled with on-line oxidation.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090101

• Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20090101

• Bioaccumulation and toxicity of selenium compounds in the green alga Scenedesmus quadricauda.

  BMC plant biology 20090101

• Effects of long-term selenium yeast supplementation on selenium status studied in the rat.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20090101

• Hematoprotective effect of seleno-L-methionine on cyclophosphamide toxicity in rats.

  Drug and chemical toxicology 20090101

• The anticancer effects of sodium selenite and selenomethionine on human colorectal carcinoma cell lines in nude mice.

  Oncology research 20090101

• Crystal structure of Bfr A from Mycobacterium tuberculosis: incorporation of selenomethionine results in cleavage and demetallation of haem.

  PloS one 20090101

• Production and characterization of fully selenomethionine-labeled Saccharomyces cerevisiae.

  Journal of agricultural and food chemistry 20081224

• Differential effects of doses and forms of dietary selenium on immune cell numbers in the skin of ultraviolet-irradiated and unirradiated mice.

  Biological trace element research 20081201

• Purification and characterization of flavin-containing monooxygenase isoform 3 from rat kidney microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20081201

• Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily.

  Nature chemical biology 20081201

• Selenium supplementation improves antioxidant capacity in vitro and in vivo in patients with coronary artery disease The SElenium Therapy in Coronary Artery disease Patients (SETCAP) Study.

  American heart journal 20081201

• Selenium-enriched garlic and cabbage as a dietary selenium source for broilers.

  Journal of medicinal food 20081201

• Effect of dietary supplementation with selenium-enriched yeast or sodium selenite on selenium tissue distribution and meat quality in beef cattle.

  Journal of animal science 20081101

• Selenium and anticarcinogenesis: underlying mechanisms.

  Current opinion in clinical nutrition and metabolic care 20081101

• Agents used for chemoprevention of prostate cancer may influence PSA secretion independently of cell growth in the LNCaP model of human prostate cancer progression.

  The Prostate 20080901

• Expression, purification, crystallization and preliminary X-ray studies of histamine dehydrogenase from Nocardioides simplex.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080901

• A Phase I and pharmacokinetic study of selenomethionine in combination with a fixed dose of irinotecan in solid tumors.

  Cancer chemotherapy and pharmacology 20080801

• A novel HPLC-UV/nano-TiO2-chemiluminescence system for the determination of selenocystine and selenomethionine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080715

• [The effect of selenium therapy on autoimmune thyroiditis].

  Orvosi hetilap 20080629

• Analysis of methionine/selenomethionine oxidation and methionine sulfoxide reductase function using methionine-rich proteins and antibodies against their oxidized forms.

  Biochemistry 20080624

• Supplementation with organic or inorganic selenium in heat-distressed quail.

  Biological trace element research 20080601

• Response of selenium status indicators to supplementation of healthy North American men with high-selenium yeast.

  Biological trace element research 20080501

• Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

• Synthesis, stabilization and formulation of [177Lu]Lu-AMBA, a systemic radiotherapeutic agent for Gastrin Releasing Peptide receptor positive tumors.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20080401

• Determination of selenocysteine and selenomethionine in edible animal tissues by 2D size-exclusion reversed-phase HPLC-ICP MS following carbamidomethylation and proteolytic extraction.

  Analytical and bioanalytical chemistry 20080401

• Synthesis of selenocysteine and selenomethionine derivatives from sulfur-containing amino acids.

  Chemistry & biodiversity 20080301

• Determination of selenium and tellurium compounds in biological samples by ion chromatography dynamic reaction cell inductively coupled plasma mass spectrometry.

  Journal of chromatography. A 20080215

• Monitoring of changes in selenium concentration in goat milk during short-term supplementation of various forms of selenium.

  Biological trace element research 20080201

• Selenomethionine labeling of large biological macromolecular complexes: probing the structure of marine bacterial virus PM2.

  Journal of structural biology 20080201

• Selenomethionine reduces visual deficits due to developmental methylmercury exposures.

  Physiology & behavior 20080128

• Total selenium and selenomethionine in pharmaceutical yeast tablets: assessment of the state of the art of measurement capabilities through international intercomparison CCQM-P86.

  Analytical and bioanalytical chemistry 20080101

• A structural code for discriminating between transcription signals revealed by the feast/famine regulatory protein DM1 in complex with ligands.

  Structure (London, England : 1993) 20071001

• Selenomethionine induces polyamine biosynthesis in regenerating rat liver tissue.

  Amino acids 20070901

• Production of selenomethionyl-derivatized proteins in baculovirus-infected insect cells.

  Protein science : a publication of the Protein Society 20070901

• Crystal structure of the VP4 protease from infectious pancreatic necrosis virus reveals the acyl-enzyme complex for an intermolecular self-cleavage reaction.

  The Journal of biological chemistry 20070824

• Methylselenol generated from selenomethionine by methioninase downregulates integrin expression and induces caspase-mediated apoptosis of B16F10 melanoma cells.

  Journal of cellular physiology 20070801

• Non-optimal levels of dietary selenomethionine alter splenocyte response and modify oxidative stress markers in female mice.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070701

• Expression, purification and crystallization of native and selenomethionine labeled Mycobacterium tuberculosis FGD1 (Rv0407) using a Mycobacterium smegmatis expression system.

  Protein expression and purification 20070701

• Effects of 12 months treatment with L-selenomethionine on serum anti-TPO Levels in Patients with Hashimoto's thyroiditis.

  Thyroid : official journal of the American Thyroid Association 20070701

• Elemental selenium at nano size possesses lower toxicity without compromising the fundamental effect on selenoenzymes: comparison with selenomethionine in mice.

  Free radical biology & medicine 20070515

• Effects of dietary selenium on tissue concentrations, pathology, oxidative stress, and immune function in common eiders (Somateria mollissima).

  Journal of toxicology and environmental health. Part A 20070515

• Speciation of selenium in a commercial dietary supplement by liquid chromatography coupled with inductively coupled plasma-mass spectrometry (ICP-MS).

  Journal of toxicology and environmental health. Part A 20070501

• Selenium metabolites in urine of cancer patients receiving L-selenomethionine at high doses.

  Toxicology and applied pharmacology 20070415

• Updated estimates of the selenomethionine content of NIST wheat reference materials by GC-IDMS.

  Analytical and bioanalytical chemistry 20070401

• Seleno-L-methionine protects against beta-amyloid and iron/hydrogen peroxide-mediated neuron death.

  Antioxidants & redox signaling 20070401

• Profiling of selenomethionine responsive genes in colon cancer by microarray analysis.

  Cancer biology & therapy 20070401

• Cloning, expression, purification, crystallization and preliminary crystallographic analysis of selenomethionine-labelled KaiC-like protein PH0186 from Pyrococcus horikoshii OT3.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20070401

• Molecular mechanisms of the chemopreventive effect on hepatocellular carcinoma development in Mdr2 knockout mice.

  Molecular cancer therapeutics 20070401

• Biomarkers of exposure and effect as indicators of the interference of selenomethionine on methylmercury toxicity.

  Toxicology letters 20070308

• Changes in gene expression profiles in response to selenium supplementation among individuals with arsenic-induced pre-malignant skin lesions.

  Toxicology letters 20070308

• Evaluation of ecological and in vitro effects of boron on prostate cancer risk (United States).

  Cancer causes & control : CCC 20070201

• Selenomethionine induced transcriptional programs in human prostate cancer cells.

  The Journal of urology 20070201

• Effect of mercury on selenium utilization and selenoperoxidase activity in LNCaP cells.

  Free radical biology & medicine 20070101

• Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides.

  BMC molecular biology 20070101

• Selenium modification of nucleic acids: preparation of oligonucleotides with incorporated 2'-SeMe-uridine for crystallographic phasing of nucleic acid structures.

  Nature protocols 20070101

• Methylation-mediated silencing of genes is not altered by selenium treatment of prostate cancer cells.

  Anticancer research 20070101

• The influence of methionine, selenomethionine, and vitamin E on liver metabolic pathways and steatosis in high-cholesterol fed rabbits.

  Biological trace element research 20070101

• Selective labeling of selenomethionine residues in proteins with a fluorescent derivative of benzyl bromide.

  Analytical biochemistry 20061215

• Reduction potential tuning of the blue copper center in Pseudomonas aeruginosa azurin by the axial methionine as probed by unnatural amino acids.

  Journal of the American Chemical Society 20061213

• Bacterial bioreactors for high yield production of recombinant protein.

  The Journal of biological chemistry 20061208

• Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20061201

• Metabolism of 76Se-methylselenocysteine compared with that of 77Se-selenomethionine and 82Se-selenite.

  Toxicology and applied pharmacology 20061201

• Selenomethionine inhibits ultraviolet radiation-induced p53 transactivation.

  Photodermatology, photoimmunology & photomedicine 20061201

• Expression, crystallization and preliminary crystallographic studies of a novel bifunctional N-acetylglutamate synthase/kinase from Xanthomonas campestris homologous to vertebrate N-acetylglutamate synthase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20061201

• Oxidative metabolism of seleno-L-methionine to L-methionine selenoxide by flavin-containing monooxygenases.

  Chemical research in toxicology 20061201

• Simultaneous tracing of 76Se-selenite and 77Se-selenomethionine by absolute labeling and speciation.

  Toxicology and applied pharmacology 20061115

• New separation method for organic and inorganic selenium compounds based on anion exchange chromatography followed by inductively coupled plasma mass spectrometry.

  Analytical and bioanalytical chemistry 20060801

• Crystallization and preliminary X-ray diffraction analysis of BipD, a virulence factor from Burkholderia pseudomallei.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Cloning, purification and preliminary crystallographic analysis of a conserved hypothetical protein, SA0961 (YlaN), from Staphylococcus aureus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060801

• Gene expression differences in normal esophageal mucosa associated with regression and progression of mild and moderate squamous dysplasia in a high-risk Chinese population.

  Cancer research 20060701

• Purification, crystallization and preliminary X-ray diffraction analysis of RafE, a sugar-binding lipoprotein from Streptococcus pneumoniae.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060701

• Direct amino acid analysis method for speciation of selenoamino acids using high-performance anion-exchange chromatography coupled with integrated pulsed amperometric detection.

  Journal of chromatography. A 20060616

• Selenium speciation by high-performance anion-exchange chromatography-post-column UV irradiation coupled with atomic fluorescence spectrometry.

  Journal of chromatography. A 20060616

• Certification of a new selenized yeast reference material (SELM-1) for methionine, selenomethinone and total selenium content and its use in an intercomparison exercise for quantifying these analytes.

  Analytical and bioanalytical chemistry 20060501

• [Determination of selenomethionine in selenium-enriched yeast by gas chromatography-mass spectrometry].

  Se pu = Chinese journal of chromatography 20060501

• Structure of the neuronal protein calexcitin suggests a mode of interaction in signalling pathways of learning and memory.

  Journal of molecular biology 20060414

• Protection against radiation-induced oxidative stress in cultured human epithelial cells by treatment with antioxidant agents.

  International journal of radiation oncology, biology, physics 20060401

• Effects of chemical form of selenium on plasma biomarkers in a high-dose human supplementation trial.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060401

• Structure of the novel alpha-amylase AmyC from Thermotoga maritima.

  Acta crystallographica. Section D, Biological crystallography 20060301

• Crystallization and preliminary crystallographic analysis of selenomethionine-labelled progesterone 5beta-reductase from Digitalis lanata Ehrh.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060301

• Crystallization and initial crystal characterization of the C-terminal phosphoglycerate mutase homology domain of Sts-1.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20060301

• A phase I and pharmacokinetic study of fixed-dose selenomethionine and irinotecan in solid tumors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060215

• Effect of pH on one-electron oxidation chemistry of organoselenium compounds in aqueous solutions.

  The journal of physical chemistry. A 20060209

• Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection?

  Acta crystallographica. Section D, Biological crystallography 20060201

• Cystathionine gamma-lyase contributes to selenomethionine detoxification and cytosolic glutathione peroxidase biosynthesis in mouse liver.

  Biological trace element research 20060201

• The central role of metal coordination in selenium antioxidant activity.

  Inorganic chemistry 20060123

• Effects of thymoquinone, lycopene, and selenomethione in the presence of estrogen on the viability of SiHa cells in vitro.

  Biomedical sciences instrumentation 20060101

• Influence of selenomethionine and vitamin E on the antioxidative system in animals with experimentally induced hypercholesterolemia.

  Biological trace element research 20060101

• Selenomethionine prevents degeneration induced by overexpression of wild-type human alpha-synuclein during differentiation of neuroblastoma cells.

  Journal of the American College of Nutrition 20051201

• X-ray crystal structures of HMG-CoA synthase from Enterococcus faecalis and a complex with its second substrate/inhibitor acetoacetyl-CoA.

  Biochemistry 20051101

• Crystallization and X-ray diffraction properties of Baeyer-Villiger monooxygenase MtmOIV from the mithramycin biosynthetic pathway in Streptomyces argillaceus.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051101

• Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.

  The Journal of biological chemistry 20051014

• Comparative effects of 2 antioxidants, selenomethionine and epigallocatechin-gallate, on catabolic and anabolic gene expression of articular chondrocytes.

  The Journal of rheumatology 20051001

• Role of the alkali labile sites, reactive oxygen species and antioxidants in DNA damage induced by methylated trivalent metabolites of inorganic arsenic.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20051001

• Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20051001

• The molecular architecture of human N-acetylgalactosamine kinase.

  The Journal of biological chemistry 20050923

• Selenium metabolites in human urine after ingestion of selenite, L-selenomethionine, or DL-selenomethionine: a quantitative case study by HPLC/ICPMS.

  Analytical and bioanalytical chemistry 20050901

• Randomized, placebo-controlled, esophageal squamous cell cancer chemoprevention trial of selenomethionine and celecoxib.

  Gastroenterology 20050901

• Dual-targeted labeling of proteins using cysteine and selenomethionine residues.

  Analytical biochemistry 20050715

• Effects of dietary selenomethionine on larval rainbow trout (Oncorhynchus mykiss).

  Archives of environmental contamination and toxicology 20050701

• Changes in serum proteomic patterns by presurgical alpha-tocopherol and L-selenomethionine supplementation in prostate cancer.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050701

• Purification and characterization of mouse hepatic enzyme that converts selenomethionine to methylselenol by its alpha,gamma-elimination.

  Biological trace element research 20050701

• Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors.

  Clinical colorectal cancer 20050701

• Structure at 1.6 A resolution of the protein from gene locus At3g22680 from Arabidopsis thaliana.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050701

• Crystallization of the C-terminal globular domain of avian reovirus fibre.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050701

• Expression, purification, crystallization and preliminary X-ray crystallographic studies of a novel acetylcitrulline deacetylase from Xanthomonas campestris.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050701

• Structure and function of both domains of ArnA, a dual function decarboxylase and a formyltransferase, involved in 4-amino-4-deoxy-L-arabinose biosynthesis.

  The Journal of biological chemistry 20050617

• Crystallization and preliminary X-ray analysis of native and selenomethionyl vinorine synthase from Rauvolfia serpentina.

  Acta crystallographica. Section D, Biological crystallography 20050601

• Identification of the major selenium compound, Se-Methionine, in three yeast (Saccharomyces cerevisiae) dietary supplements by on-line narrowbore liquid chromatography-electrospray tandem mass spectrometry.

  Journal of chromatography. A 20050415

• Protocols for production of selenomethionine-labeled proteins in 2-L polyethylene terephthalate bottles using auto-induction medium.

  Protein expression and purification 20050401

• Structure of CDP-D-glucose 4,6-dehydratase from Salmonella typhi complexed with CDP-D-xylose.

  Acta crystallographica. Section D, Biological crystallography 20050401

• Crystallization and preliminary X-ray crystallographic analysis of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Mycobacterium tuberculosis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050401

• Chiral speciation and determination of DL-selenomethionine enantiomers on a novel chiral ligand-exchange stationary phase.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050301

• Effect of the chemical form of supranutritional selenium on selenium load and selenoprotein activities in virgin, pregnant, and lactating rats.

  Journal of animal science 20050201

• Structures of dCTP deaminase from Escherichia coli with bound substrate and product: reaction mechanism and determinants of mono- and bifunctionality for a family of enzymes.

  The Journal of biological chemistry 20050128

• Susceptibility to hypoxia/reoxygenation of aged rat cardiomyocytes and its modulation by selenium supplementation.

  Journal of agricultural and food chemistry 20050126

• Identification of selenomethionine in selenized yeast using two-dimensional liquid chromatography-mass spectrometry based proteomic analysis.

  The Analyst 20050101

• Determination of methionine and selenomethionine in selenium-enriched yeast by species-specific isotope dilution with liquid chromatography-mass spectrometry and inductively coupled plasma mass spectrometry detection.

  Analytical chemistry 20050101

• Crystal structure of THEP1 from the hyperthermophile Aquifex aeolicus: a variation of the RecA fold.

  BMC structural biology 20050101

• Selenium supplementation may increase the efficacy of cetuximab in metastatic colorectal cancer patients.

  Medical hypotheses 20050101

• Glomerular response to adrenocortical hormone alone or in combination with selenomethionine.

  Biomedical sciences instrumentation 20050101

• Interactions between different selenium compounds and zinc, cadmium and mercury.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20050101

• Incorporation of selenomethionine into induced intracytoplasmic membrane proteins of Rhodobacter species.

  Journal of structural and functional genomics 20050101

• Identification of mouse selenomethionine alpha,gamma-elimination enzyme: cystathionine gamma-lyase catalyzes its reaction to generate methylselenol.

  Biological trace element research 20050101

• Crystallization of the glycogen-binding domain of the AMP-activated protein kinase beta subunit and preliminary X-ray analysis.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20050101

• L-Methioninium chloride and L-selenomethioninium chloride at 103 K.

  Acta crystallographica. Section C, Crystal structure communications 20041201

• Crystallization and preliminary X-ray analysis of the Streptomyces olivaceoviridis NgcE binding protein of the ABC transporter for N-acetylglucosamine.

  Acta crystallographica. Section D, Biological crystallography 20041201

• Determination of selenomethionine and selenocysteine in human serum using speciated isotope dilution-capillary HPLC-inductively coupled plasma collision cell mass spectrometry.

  Analytical chemistry 20041115

• Comparison of extraction methods for quantitation of methionine and selenomethionine in yeast by species specific isotope dilution gas chromatography-mass spectrometry.

  Journal of chromatography. A 20041105

• [Studies on comparing the toxicity between sodium selenite and selenomethionine in rats].

  Wei sheng yan jiu = Journal of hygiene research 20041101

• Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine.

  Biochemistry 20041026

• Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase.

  Biochemistry 20041026

• The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus.

  The Journal of biological chemistry 20041015

• Structure of the Thermus thermophilus putative periplasmic glutamate/glutamine-binding protein.

  Acta crystallographica. Section D, Biological crystallography 20041001

• Expression, purification and preliminary crystallographic analysis of dipeptidyl peptidase IV from Porphyromonas gingivalis.

  Acta crystallographica. Section D, Biological crystallography 20041001

• Determination of methionine and selenomethionine in yeast by species-specific isotope dilution GC/MS.

  Analytical chemistry 20040901

• The family 11 carbohydrate-binding module of Clostridium thermocellum Lic26A-Cel5E accommodates beta-1,4- and beta-1,3-1,4-mixed linked glucans at a single binding site.

  The Journal of biological chemistry 20040813

• A dimerized coiled-coil domain and an adjoining part of geminin interact with two sites on Cdt1 for replication inhibition.

  Molecular cell 20040723

• Temperature and cryoprotectant influence secondary quinone binding position in bacterial reaction centers.

  FEBS letters 20040716

• Study of selenium distribution in the protein fractions of the Brazil nut, Bertholletia excelsa.

  Journal of agricultural and food chemistry 20040630

• Structure of the molybdenum-cofactor biosynthesis protein MoaB of Escherichia coli.

  Acta crystallographica. Section D, Biological crystallography 20040601

• Crystallization and preliminary X-ray analysis of alpha-isopropylmalate synthase from Mycobacterium tuberculosis.

  Acta crystallographica. Section D, Biological crystallography 20040601

• Metabolism of selenomethionine by rainbow trout (Oncorhynchus mykiss) embryos can generate oxidative stress.

  Ecotoxicology and environmental safety 20040501

• Crystallization and preliminary analysis of xenobiotic reductase A and ligand complexes from Pseudomonas putida II-B.

  Acta crystallographica. Section D, Biological crystallography 20040501

• Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription.

  Molecular cancer therapeutics 20040501

• Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040401

• Selenomethionine contents of NIST wheat reference materials.

  Analytical and bioanalytical chemistry 20040301

• Expression and crystallization of several forms of the Propionibacterium shermanii transcarboxylase 5S subunit.

  Acta crystallographica. Section D, Biological crystallography 20040301

• Purification, crystallization and preliminary X-ray analysis of native and selenomethionine class I tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes.

  Acta crystallographica. Section D, Biological crystallography 20040301

• Crystallization and preliminary X-ray analysis of family 39 beta-D-xylosidase from Geobacillus stearothermophilus T-6.

  Acta crystallographica. Section D, Biological crystallography 20040301

• Determination of the absolute configuration of selenomethionine from antarctic krill by RP-HPLC/ICP-MS using chiral derivatization agents.

  Analytical and bioanalytical chemistry 20040301

• Identification and characterization of Se-methyl selenomethionine in Brassica juncea roots.

  Journal of chromatography. A 20040213

• Crystallization and preliminary crystallographic analysis of Mycoplasma arthritidis-derived mitogen complexed with peptide/MHC class II antigen.

  Acta crystallographica. Section D, Biological crystallography 20040201

• Methioninase and selenomethionine but not Se-methylselenocysteine generate methylselenol and superoxide in an in vitro chemiluminescent assay: implications for the nutritional carcinostatic activity of selenoamino acids.

  Biochemical pharmacology 20040201

• The purification, crystallization and preliminary structural characterization of PhzF, a key enzyme in the phenazine-biosynthesis pathway from Pseudomonas fluorescens 2-79.

  Acta crystallographica. Section D, Biological crystallography 20040101

• Highly UV-absorbing complex in selenomethionine-substituted alcohol dehydrogenase from Sulfolobus solfataricus.

  Journal of proteome research 20040101

• Production of selenomethionine-labeled proteins in two-liter plastic bottles for structure determination.

  Journal of structural and functional genomics 20040101

• Selenium compounds regulate p53 by common and distinctive mechanisms.

  Anticancer research 20040101

• Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium.

  BMC genomics 20040101

• Selenomethionine stimulates MAPK (ERK) phosphorylation, protein oxidation, and DNA synthesis in gastric cancer cells.

  Nutrition and cancer 20040101

• Induction of the mitochondrial permeability transition by selenium compounds mediated by oxidation of the protein thiol groups and generation of the superoxide.

  Biochemical pharmacology 20031215

• Crystallization and preliminary crystallographic studies of the C-terminal domain of human FKBP52.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Purification, crystallization and preliminary X-ray diffraction analysis of S-formylglutathione hydrolase from Arabidopsis thaliana: effects of pressure and selenomethionine substitution on space-group changes.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Crystallization and preliminary X-ray analysis of the small component of 4-hydroxyphenylacetate 3-monooxygenase (HpaC) and its cofactor complex from Thermus thermophilus HB8.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Expression, crystallization and preliminary X-ray crystallographic studies of Arthrobacter globiformis inulin fructotransferase.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Crystallization and preliminary X-ray analysis of N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Crystallization and preliminary X-ray analysis of the glycogen synthase from Pyrococcus abyssi.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Selling candles in a post-Edison world: phasing with noble gases bound within engineered sites.

  Acta crystallographica. Section D, Biological crystallography 20031101

• Selenomethionine and selenocysteine double labeling strategy for crystallographic phasing.

  Structure (London, England : 1993) 20031101

• Sulfur and selenium: the role of oxidation state in protein structure and function.

  Angewandte Chemie (International ed. in English) 20031013

• Effects of salinity on the uptake, biotransformation, and toxicity of dietary seleno-L-methionine to rainbow trout.

  Toxicological sciences : an official journal of the Society of Toxicology 20031001

• Identification of selenium species in urine by ion-pairing HPLC-ICP-MS using laboratory-synthesized standards.

  Analytical and bioanalytical chemistry 20031001

• Purification, crystallization and preliminary crystallographic analysis of phosphoglucose isomerase from the hyperthermophilic archaeon Pyrococcus furiosus.

  Acta crystallographica. Section D, Biological crystallography 20031001

• Purification and crystallization of Escherichia coli pseudouridine synthase RluD.

  Acta crystallographica. Section D, Biological crystallography 20031001

• Crystal structure of Pyrococcus furiosus phosphoglucose isomerase. Implications for substrate binding and catalysis.

  The Journal of biological chemistry 20030829

• Molecular structure of galactokinase.

  The Journal of biological chemistry 20030829

• Structure of E. coli ketopantoate hydroxymethyl transferase complexed with ketopantoate and Mg2+, solved by locating 160 selenomethionine sites.

  Structure (London, England : 1993) 20030801

• Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids.

  Journal of the American Chemical Society 20030723

• Characteristics of selenazolidine prodrugs of selenocysteine: toxicity and glutathione peroxidase induction in V79 cells.

  Journal of medicinal chemistry 20030717

• Crystallization and X-ray analysis of a bacterial non-haem iron-containing phenylalanine hydroxylase from the Gram-negative opportunistic pathogen Pseudomonas aeruginosa.

  Acta crystallographica. Section D, Biological crystallography 20030701

• NO produced by endothelial NO synthase is a mediator of delayed preconditioning-induced endothelial protection.

  American journal of physiology. Heart and circulatory physiology 20030601

• Methioninase gene therapy with selenomethionine induces apoptosis in bcl-2-overproducing lung cancer cells.

  Cancer gene therapy 20030601

• High-resolution structure of human phosphoserine phosphatase in open conformation.

  Acta crystallographica. Section D, Biological crystallography 20030601

• Shotgun crystallization strategy for structural genomics: an optimized two-tiered crystallization screen against the Thermotoga maritima proteome.

  Acta crystallographica. Section D, Biological crystallography 20030601

• Crystallization and preliminary X-ray studies of the glutaredoxin from poplar in complex with glutathione.

  Acta crystallographica. Section D, Biological crystallography 20030601

• Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.

  Angewandte Chemie (International ed. in English) 20030525

• Activity, conformation and dynamics of cutinase adsorbed on poly(methyl methacrylate) latex particles.

  Journal of biotechnology 20030508

• Crystallization and preliminary crystallographic analysis of yeast cytosine deaminase.

  Acta crystallographica. Section D, Biological crystallography 20030501

• Selenium protects primary human keratinocytes from apoptosis induced by exposure to ultraviolet radiation.

  Clinical and experimental dermatology 20030501

• Effects of selenium compounds on induction of DNA damage by broadband ultraviolet radiation in human keratinocytes.

  The British journal of dermatology 20030501

• Effects of a six month treatment with selenomethionine in patients with autoimmune thyroiditis.

  European journal of endocrinology 20030401

• Selenium supplementation can protect cultured rat cardiomyocytes from hypoxia/reoxygenation damage.

  Journal of agricultural and food chemistry 20030312

• Structural basis by which alternative splicing confers specificity in fibroblast growth factor receptors.

  Proceedings of the National Academy of Sciences of the United States of America 20030304

• Selenomethionine does not affect PSA secretion independent of its effect on LNCaP cell growth.

  The Prostate 20030301

• Methionine changes in bacteriorhodopsin detected by FTIR and cell-free selenomethionine substitution.

  Biophysical journal 20030201

• Crystal structure of tabtoxin resistance protein complexed with acetyl coenzyme A reveals the mechanism for beta-lactam acetylation.

  Journal of molecular biology 20030131

• Selenium for prevention: eating your way to better DNA repair?

  Journal of the National Cancer Institute 20030115

• Vitamin E succinate inhibits human prostate cancer cell growth via modulating cell cycle regulatory machinery.

  Biochemical and biophysical research communications 20030110

• Catechol-O-methyltransferase inhibition protects against 3,4-dihydroxyphenylalanine (DOPA) toxicity in primary mesencephalic cultures: new insights into levodopa toxicity.

  Neurochemistry international 20030101

• Hydrolysis of proteins with methanesulfonic acid for improved HPLC-ICP-MS determination of seleno-methionine in yeast and nuts.

  Analytical and bioanalytical chemistry 20030101

• Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability.

  Biophysical chemistry 20030101

• The effects of sustained delivery of glucocorticoids on the adrenal gland of male rats.

  Biomedical sciences instrumentation 20030101

• The role of sustained delivery of corticosterone alone or in combination with antioxidants on the cardiovascular system of adult female rats.

  Biomedical sciences instrumentation 20030101

• Peroxynitrite triggers a delayed resistance of coronary endothelial cells against ischemia-reperfusion injury.

  American journal of physiology. Heart and circulatory physiology 20021001

• Stability of total selenium and selenium species in lyophilised oysters and in their enzymatic extracts.

  Analytical and bioanalytical chemistry 20021001

• An essential role of s-adenosyl-L-methionine:L-methionine s-methyltransferase in selenium volatilization by plants. Methylation of selenomethionine to selenium-methyl-L-selenium- methionine, the precursor of volatile selenium.

  Plant physiology 20021001

• Characterization of selenium species in Brazil nuts by HPLC-ICP-MS and ES-MS.

  Journal of agricultural and food chemistry 20020925

• Study of the stability of selenium compounds in human urine and determination by mixed ion-pair reversed-phase chromatography with ICP-MS detection.

  Analytical and bioanalytical chemistry 20020901

• Methylseleno-amino acid content of food materials by stable isotope dilution mass spectrometry.

  Food and nutrition bulletin 20020901

• Expression of selenomethionyl proteins in a prototrophic strain of Escherichia coli.

  Analytical biochemistry 20020801

• Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol.

  Molecular carcinogenesis 20020701

• The crystal structure of Mycobacterium tuberculosis alkylhydroperoxidase AhpD, a potential target for antitubercular drug design.

  The Journal of biological chemistry 20020531

• 3-Carboxy-cis,cis-muconate lactonizing enzyme from Neurospora crassa: MAD phasing with 80 selenomethionines.

  Acta crystallographica. Section D, Biological crystallography 20020501

• Role of selenium toxicity and oxidative stress in aquatic birds.

  Aquatic toxicology (Amsterdam, Netherlands) 20020401

• Selenium toxicity: cause and effects in aquatic birds.

  Aquatic toxicology (Amsterdam, Netherlands) 20020401

• Selenite and selenomethionine promote HL-60 cell cycle progression.

  The Journal of nutrition 20020401

• Modulation of apoptosis and improved redox metabolism with the use of a new antioxidant formula.

  Biochemical pharmacology 20020401

• Jolly SAD.

  Acta crystallographica. Section D, Biological crystallography 20020301

• Crystallization and X-ray analysis of native and selenomethionyl beta-mannanase Man5A from blue mussel, Mytilus edulis, expressed in Pichia pastoris.

  Acta crystallographica. Section D, Biological crystallography 20020301

• Crystallization and preliminary X-ray crystallographic studies on acyl-(acyl carrier protein) from Escherichia coli.

  Acta crystallographica. Section D, Biological crystallography 20020201

• Production of selenohomocystine as an antibiotic by a marine Bacillus sp. no. 14 with selenomethionine resistance.

  The Journal of antibiotics 20020201

• Capillary gas chromatography inductively coupled plasma mass spectrometry (CGC-ICPMS) for the enantiomeric analysis of D,L-selenomethionine in food supplements and urine.

  Journal of pharmaceutical and biomedical analysis 20020115

• Bioavailability of selenium from raw or cured selenomethionine-enriched fillets of Atlantic salmon (Salmo salar) assessed in selenium-deficient rats.

  The British journal of nutrition 20020101

• Selenomethionine inhibits growth and suppresses cyclooxygenase-2 (COX-2) protein expression in human colon cancer cell lines.

  Cancer biology & therapy 20020101

• Growth characteristics and selenium status changes of yeast cells with inorganic and organic selenium supplementation: selenium, a chemopreventive agent.

  Journal of medicinal food 20020101

• Selenomethionine incorporation into a protein by cell-free synthesis.

  Journal of structural and functional genomics 20020101

• Crystal structure of Escherichia coli ketopantoate reductase at 1.7 A resolution and insight into the enzyme mechanism.

  Biochemistry 20011204

• The structure of the feruloyl esterase module of xylanase 10B from Clostridium thermocellum provides insights into substrate recognition.

  Structure (London, England : 1993) 20011201

• Transport measurements across Caco-2 monolayers of different organic and inorganic selenium: influence of sulfur compounds.

  Biological trace element research 20011201

• High-resolution experimental phases for tryptophanyl-tRNA synthetase (TrpRS) complexed with tryptophanyl-5'AMP.

  Acta crystallographica. Section D, Biological crystallography 20011101

• Crystallization and preliminary X-ray analysis of the archaeosine tRNA-guanine transglycosylase from Pyrococcus horikoshii.

  Acta crystallographica. Section D, Biological crystallography 20011101

• The 1.2 A structure of a novel quorum-sensing protein, Bacillus subtilis LuxS.

  Journal of molecular biology 20011012

• Contribution of enzymic alpha, gamma-elimination reaction in detoxification pathway of selenomethionine in mouse liver.

  Toxicology and applied pharmacology 20011001

• Selenomethionine substitution of orotidine-5'-monophosphate decarboxylase causes a change in crystal contacts and space group.

  Acta crystallographica. Section D, Biological crystallography 20010901

• Crystallization and preliminary diffraction studies of native and selenomethionine CcmG (CycY, DsbE).

  Acta crystallographica. Section D, Biological crystallography 20010901

• Effect of selenomethionine on N-methylnitronitrosoguanidine-induced colonic aberrant crypt foci in rats.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20010801

• Pteridine reductase mechanism correlates pterin metabolism with drug resistance in trypanosomatid parasites.

  Nature structural biology 20010601

• Selenomethionine content of candidate reference materials.

  Fresenius' journal of analytical chemistry 20010601

• Hybridation of different chiral separation techniques with ICP-MS detection for the separation and determination of selenomethionine enantiomers: chiral speciation of selenized yeast.

  Biomedical chromatography : BMC 20010501

• Crystallization and functional analysis of a soluble deglycosylated form of the human costimulatory molecule B7-1.

  Acta crystallographica. Section D, Biological crystallography 20010401

• Interactions of selenium compounds with other antioxidants in DNA damage and apoptosis in human normal keratinocytes.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010401

• Comparative effects of high dietary levels of organic and inorganic selenium on selenium toxicity of growing-finishing pigs.

  Journal of animal science 20010401

• Prolonged feeding of high dietary levels of organic and inorganic selenium to gilts from 25 kg body weight through one parity.

  Journal of animal science 20010401

• Selenium decreases thyroglobulin concentrations but does not affect the increased thyroxine-to-triiodothyronine ratio in children with congenital hypothyroidism.

  The Journal of clinical endocrinology and metabolism 20010301

• Crystallization and preliminary X-ray analysis of native and selenomethionine fructose-1,6-bisphosphate aldolase from Thermus aquaticus.

  Acta crystallographica. Section D, Biological crystallography 20010201

• Selenomethionine incorporation in Saccharomyces cerevisiae RNA polymerase II.

  Structure (London, England : 1993) 20010110

• Plasma selenium in specific and non-specific forms.

  BioFactors (Oxford, England) 20010101

• Selenium (Se) from high-selenium broccoli is utilized differently than selenite, selenate and selenomethionine, but is more effective in inhibiting colon carcinogenesis.

  BioFactors (Oxford, England) 20010101

• Dimethyldiselenide and methylseleninic acid generate superoxide in an in vitro chemiluminescence assay in the presence of glutathione: implications for the anticarcinogenic activity of L-selenomethionine and L-Se-methylselenocysteine.

  Nutrition and cancer 20010101

• Selenium and the brain: a review.

  Nutritional neuroscience 20010101

• Increased production of proinflammatory cytokines by murine macrophages following oral exposure to sodium selenite but not to seleno-L-methionine.

  Archives of environmental contamination and toxicology 20000801

• Crystal structures of the metal-dependent 2-dehydro-3-deoxy-galactarate aldolase suggest a novel reaction mechanism.

  The EMBO journal 20000801