3307-39-9 | 2-(4-Chlorophenoxy) propionic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$41.00	$29.00
5g	98%	in stock	$105.00	$74.00
10g	98%	in stock	$169.00	$118.00
25g	98%	in stock	$297.00	$208.00
100g	98%	in stock	$758.00	$531.00

Description

• Catalog Number: AB05238
• Chemical Name: 2-(4-Chlorophenoxy) propionic acid
• CAS Number: 3307-39-9
• Molecular Formula: C9H9ClO3
• Molecular Weight: 200.619
• MDL Number: MFCD00002647
• SMILES: CC(C(=O)O)Oc1ccc(cc1)Cl
• NSC Number: 70174

Computed Properties

• Complexity: 176
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1
• XLogP3: 2.3

Literature

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  Toxicology letters 20110325

• Purification and gene cloning of an enantioselective thioesterification enzyme from Brevibacterium ketoglutamicum KU1073, a deracemization bacterium of 2-(4-chlorophenoxy)propanoic acid.

  Bioscience, biotechnology, and biochemistry 20100101

• Physiology and pathophysiology of ClC-K/barttin channels.

  Frontiers in physiology 20100101

• Molecular Pharmacology of Kidney and Inner Ear CLC-K Chloride Channels.

  Frontiers in pharmacology 20100101

• Combined use of biomarkers and in situ bioassays in Daphnia magna to monitor environmental hazards of pesticides in the field.

  Environmental toxicology and chemistry 20070201

• Radiolytic degradation of herbicide 4-chloro-2-methyl phenoxyacetic acid (MCPA) by gamma-radiation for environmental protection.

  Ecotoxicology and environmental safety 20061001

• Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.

  International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20060501

• Channel or transporter? The CLC saga continues.

  Experimental physiology 20060101

• Activation and inhibition of kidney CLC-K chloride channels by fenamates.

  Molecular pharmacology 20060101

• Diversity of Cl(-) channels.

  Cellular and molecular life sciences : CMLS 20060101

• Phenoxyacetic acid herbicide exposure for women on Ontario farms.

  Journal of toxicology and environmental health. Part A 20050813

• Molecular determinants of differential pore blocking of kidney CLC-K chloride channels.

  EMBO reports 20040601

• CLC-K channels: if the drug fits, use it.

  EMBO reports 20040601

• Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers.

  Journal of the American Society of Nephrology : JASN 20040101

• Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.

  British journal of pharmacology 20030801

• Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid.

  Molecular pharmacology 20020801

• Exposure to pesticides as risk factor for non-Hodgkin's lymphoma and hairy cell leukemia: pooled analysis of two Swedish case-control studies.

  Leukemia & lymphoma 20020501

• Fast and slow gating of CLC-1: differential effects of 2-(4-chlorophenoxy) propionic acid and dominant negative mutations.

  Molecular pharmacology 20010701

• [Pharmacological analysis of the antihypoxic action of aminobutyric acid derivatives].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101

• Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives.

  Molecular pharmacology 20000901

• Modulation of the gating of CIC-1 by S-(-) 2-(4-chlorophenoxy) propionic acid.

  British journal of pharmacology 19990301