33775-94-9 | 2-Iodothioanisole

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$16.00	$11.00
1g	98%	in stock	$23.00	$16.00
5g	98%	in stock	$60.00	$42.00
25g	98%	in stock	$168.00	$117.00
100g	98%	in stock	$599.00	$419.00

Description

• Catalog Number: AB62412
• Chemical Name: 2-Iodothioanisole
• CAS Number: 33775-94-9
• Molecular Formula: C7H7IS
• Molecular Weight: 250.09995000000004
• MDL Number: MFCD00051611
• SMILES: CSc1ccccc1I

Computed Properties

• Complexity: 85
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 3.1

Upstream Synthesis Route

(2-Iodophenyl)(methyl)sulfane, also known as iodosylmethylsulfane, is a versatile chemical reagent widely utilized in organic synthesis. It plays a crucial role in various reactions due to its unique properties.One of the key applications of (2-Iodophenyl)(methyl)sulfane in chemical synthesis is its involvement in the sulfenylation of various nucleophiles. By serving as a sulfenylation agent, iodosylmethylsulfane can introduce a sulfanyl group to different substrates, enabling the formation of new carbon-sulfur bonds. This transformation is particularly valuable in the preparation of sulfur-containing compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science.Moreover, iodosylmethylsulfane is also employed in the oxidative transformations of organic molecules. Its ability to act as a mild and selective oxidant allows for the conversion of various functional groups, such as alcohols and thiols, into their corresponding carbonyl compounds. This oxidative capacity makes iodosylmethylsulfane a valuable tool in synthetic methodologies aimed at structural modifications and diversifications.Overall, the diverse reactivity and utility of (2-Iodophenyl)(methyl)sulfane make it a valuable reagent in organic synthesis, enabling the efficient construction of complex molecules and facilitating the discovery of novel chemical entities.

Literature

• Synthesis of 2,3-disubstituted benzo[b]thiophenes via palladium-catalyzed coupling and electrophilic cyclization of terminal acetylenes.

  The Journal of organic chemistry 20020322