34183-22-7 | 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$18.00	$13.00
5g	99%	in stock	$56.00	$39.00
25g	98%	in stock	$163.00	$114.00
100g	98%	in stock	$387.00	$271.00

Description

• Catalog Number: AB51483
• Chemical Name: 1-{2-[2-hydroxy-3-(propylamino)propoxy]phenyl}-3-phenylpropan-1-one hydrochloride
• CAS Number: 34183-22-7
• Molecular Formula: C21H28ClNO3
• Molecular Weight: 377.9049
• MDL Number: MFCD00079243
• SMILES: CCCNCC(COc1ccccc1C(=O)CCc1ccccc1)O.Cl
• NSC Number: 758640

Computed Properties

• Complexity: 368
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 11
• Undefined Atom Stereocenter Count: 1

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• A three-dimensional model for the substrate binding domain of the multidrug ATP binding cassette transporter LmrA.

  Molecular pharmacology 20041101

• The low-potency, voltage-dependent HERG blocker propafenone--molecular determinants and drug trapping.

  Molecular pharmacology 20041101

• Flecainide and propafenone induced ST-segment elevation in patients with atrial fibrillation: clue to specificity of Brugada-type electrocardiographic changes.

  The American journal of cardiology 20041101

• Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.

  Pacing and clinical electrophysiology : PACE 20041101

• [Propafenone hepatotoxicity].

  Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20041001

• Limitations to antiarrhythmic drug use in patients with atrial fibrillation.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20040928

• Evaluation of KCB-328, a new IKr blocking antiarrhythmic agent in pacing induced canine atrial fibrillation.

  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20040901

• Effectiveness of oral propafenone for the prevention of atrial fibrillation after coronary artery bypass grafting.

  The American journal of cardiology 20040901

• A rapid HPLC assay for the simultaneous determination of propafenone and its major metabolites in human serum.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040901

• Ibutilide added to propafenone for the conversion of atrial fibrillation and atrial flutter.

  Journal of the American College of Cardiology 20040818

• Use of ibutilide in cardioversion of patients with atrial fibrillation or atrial flutter treated with class IC agents.

  Journal of the American College of Cardiology 20040818

• Atrial-selective antiarrhythmic actions of novel Ikur vs. Ikr, Iks, and IKAch class Ic drugs and beta blockers in pigs.

  Medical science monitor : international medical journal of experimental and clinical research 20040701

• [Intravenous propafenone for conversion of atrial fibrillation in the emergency room].

  Harefuah 20040701

• Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation.

  The American journal of cardiology 20040615

• Lead identification for modulators of multidrug resistance based on in silico screening with a pharmacophoric feature model.

  Archiv der Pharmazie 20040601

• Intramolecular distribution of hydrophobicity influences pharmacological activity of propafenone-type MDR modulators.

  Archiv der Pharmazie 20040601

• Efficacy of propafenone for maintaining sinus rhythm in patients with recent onset or persistent atrial fibrillation after conversion: a randomized, placebo-controlled study.

  Acta cardiologica 20040601

• Atrial fibrillation (acute).

  Clinical evidence 20040601

• [Treatment of atrial fibrillation in a Hungarian hospital department of cardiologic internal medicine at the turn of the millennium].

  Orvosi hetilap 20040509

• Typical counterclockwise atrial flutter occurring despite absence of the inferior vena cava.

  Heart rhythm 20040501

• Metabolism of propafenone and verapamil by cryopreserved human, rat, mouse and dog hepatocytes: comparison with metabolism in vivo.

  Naunyn-Schmiedeberg's archives of pharmacology 20040401

• Atrial fibrillation: rate control often better than rhythm control.

  Prescrire international 20040401

• Quantitative modelling of interaction of propafenone with sodium channels in cardiac cells.

  Medical & biological engineering & computing 20040301

• Enantioselective assay of S+ - and R- -propafenone in human urine by using RP-HPLC with pre-column chiral derivatization.

  Journal of Zhejiang University. Science 20040201

• Long-term maintenance of normal sinus rhythm in patients with current symptomatic atrial fibrillation: amiodarone vs propafenone, both in low doses.

  Chest 20040201

• Propafenone and its metabolites preferentially inhibit IKr in rabbit ventricular myocytes.

  The Journal of pharmacology and experimental therapeutics 20040101

• Ventricular tachycardia as a presenting symptom in a child with thrombotic thrombocytopenic purpura.

  Thrombosis and haemostasis 20040101

• High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method.

  Xenobiotica; the fate of foreign compounds in biological systems 20040101

• [Interaction between ipriflavone and other drugs in metabolism in vitro].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040101

• Effects of propafenone associated with propofol on myocardial contractility, heart rate, coronary flow, and the incidence of arrhythmia in isolated hearts of rats.

  Arquivos brasileiros de cardiologia 20040101

• Acute toxicity of propafenone in a case of suicidal attempt.

  Bratislavske lekarske listy 20040101

• Zebrafish embryos express an orthologue of HERG and are sensitive toward a range of QT-prolonging drugs inducing severe arrhythmia.

  Toxicology and applied pharmacology 20031215

• Reproducible efficacy of loading oral propafenone in restoring sinus rhythm in patients with paroxysmal atrial fibrillation.

  The American journal of cardiology 20031201

• Influence of CYP2D6*10B genotype on pharmacokinetics of propafenone enantiomers in Chinese subjects.

  Acta pharmacologica Sinica 20031201

• Transient platypnea-orthodeoxia-like syndrome induced by propafenone overdose in a young woman with Ebstein's anomaly.

  Italian heart journal : official journal of the Italian Federation of Cardiology 20031201

• Minipig as a model for drug metabolism in man: comparison of in vitro and in vivo metabolism of propafenone.

  Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20031201

• Atrial fibrillation (acute).

  Clinical evidence 20031201

• Three-dimensional quantitative structure-activity relationship analysis of propafenone-type multidrug resistance modulators: influence of variable selection on test set predictivity.

  Journal of medicinal chemistry 20031106

• A subset of highly effective propafenone-type multidrug resistance modulators lacks effects on cardiac action potential and mechanical twitch parameters of rat papillary muscles.

  The Journal of pharmacology and experimental therapeutics 20031101

• Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation.

  The American journal of cardiology 20031015

• Pharmacological treatment of young children with permanent junctional reciprocating tachycardia.

  Cardiology in the young 20031001

• Concentration dependent stereoselectivity of propafenone N-depropylation metabolism with human hepatic recombinant CYP1A2.

  Die Pharmazie 20030901

• Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.

  Cardiac electrophysiology review 20030901

• Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.

  Cardiac electrophysiology review 20030901

• Facilitating electrical cardioversion of persistant atrial fibrillation by antiarrhythmic drugs: update on clinical trial results.

  Cardiac electrophysiology review 20030901

• A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.

  The Journal of biological chemistry 20030725

• Transient intraventricular conduction delay associated with concurrent intake of propafenone and antineoplastic agents.

  Cardiovascular drugs and therapy 20030701

• Safety and feasibility of a clinical pathway for the outpatient initiation of antiarrhythmic medications in patients with atrial fibrillation or atrial flutter.

  The American journal of cardiology 20030615

• Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.

  Cardiac electrophysiology review 20030601

• Effects of acute ischemia, early extrabeats and propafenone on complex activation patterns in intact and ischemic canine hearts.

  Life sciences 20030502

• Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

  The American journal of cardiology 20030320

• Pharmacologic and nonpharmacologic options to maintain sinus rhythm: guideline-based and new approaches.

  The American journal of cardiology 20030320

• Excitable gap composition in the presence of antiarrhythmic drugs in common human atrial flutter.

  The Canadian journal of cardiology 20030315

• Molecular site of action of the antiarrhythmic drug propafenone at the voltage-operated potassium channel Kv2.1.

  Molecular pharmacology 20030301

• Effects of propafenone and its main metabolite, 5-hydroxypropafenone, on HERG channels.

  Cardiovascular research 20030301

• Left atrial size after cardioversion for atrial fibrillation: effect of external direct current shock.

  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 20030301

• Propafenone versus ibutilide for post operative atrial fibrillation following cardiac surgery: neither strategy improves outcomes compared to rate control alone (the PIPAF study).

  Medical science monitor : international medical journal of experimental and clinical research 20030301

• Effects of a series of dihydroanthracene derivatives on drug efflux in multidrug resistant cancer cells.

  European journal of medicinal chemistry 20030301

• Propafenone hepatotoxicity: report of two new cases.

  Digestive diseases and sciences 20030201

• Stereoselectivity in trans-tramadol metabolism and trans-O-demethyltramadol formation in rat liver microsomes.

  Acta pharmacologica Sinica 20030101

• New multidrug resistance reversal agents.

  Current drug targets 20030101

• Intracardiac low-energy versus transthoracic high-energy direct-current cardioversion of atrial fibrillation: a randomised comparison.

  Cardiology 20030101

• Electrophysiological mapping and histological examinations of the swine atrium with sustained (> or =24 h) atrial fibrillation: a suitable animal model for studying human atrial fibrillation.

  Cardiology 20030101

• Unintentional pediatric overdose of propafenone.

  The Annals of pharmacotherapy 20030101

• Long-term follow-up of sudden cardiac arrest survivors and electrophysiologically guided antiarrhythmic therapy.

  Cardiology 20030101

• MCASE study of the multidrug resistance reversal activity of propafenone analogs.

  Journal of computer-aided molecular design 20030101

• Fatal propafenone overdoses: case reports and a review of the literature.

  Journal of analytical toxicology 20030101

• [Propafenone poisoning].

  Therapie 20030101

• [Fatal poisoning with propafenone: a case report documented with blood concentration levels].

  Therapie 20030101

• Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study).

  The American journal of cardiology 20021215

• Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021101

• Effect of CYP2D6*10 genotype on propafenone pharmacodynamics in Chinese patients with ventricular arrhythmia.

  Acta pharmacologica Sinica 20021101

• Similarity based SAR (SIBAR) as tool for early ADME profiling.

  Journal of computer-aided molecular design 20021101

• New insights into the mechanisms and management of atrial fibrillation.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021029

• Beta-adrenergic stimulation modulates the sodium current block by propafenone in rat ventricular myocardium.

  Journal of electrocardiology 20021001

• Long-term clinical significance of frequent and complex ventricular tachyarrhythmias in trained athletes.

  Journal of the American College of Cardiology 20020807

• Congenital junctional ectopic tachycardia in children and adolescents: a 20 year experience based study.

  Heart (British Cardiac Society) 20020801

• Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine.

  British journal of pharmacology 20020701

• Amiodarone: pearl or peril?

  European heart journal 20020701

• Amiodarone reduces procedures and costs related to atrial fibrillation in a controlled clinical trial.

  European heart journal 20020701

• [Proarrhythmic effects of propafenone in a woman with hepatopathy: is it always a simple drug in clinical practice?].

  Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20020701

• Propafenone-related cholestatic hepatitis in an elderly patient.

  Italian heart journal : official journal of the Italian Federation of Cardiology 20020701

• Intermittent Brugada syndrome misdiagnosed as acute myocardial infarction and unmasked with propafenone.

  Heart (British Cardiac Society) 20020601

• An evaluation of the strategy of maintenance of sinus rhythm by antiarrhythmic drug therapy after ablation and pacing therapy in patients with paroxysmal atrial fibrillation.

  European heart journal 20020601

• [The treatment of postoperative junctional ectopic tachycardia].

  Anales espanoles de pediatria 20020601

• Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation.

  American heart journal 20020601

• [Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study].

  Archives des maladies du coeur et des vaisseaux 20020601

• [Structure and activity relationship of propafenone and alkylesters of 2-and 4-[(3-propylamino-2-hydroxy)-propoxy]-phenylcarbamic acid].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20020501

• Paroxysmal supraventricular tachycardia induced by oral stimulation: a case report and review of swallow-induced dysrhythmias.

  The Journal of emergency medicine 20020501

• Effect of propafenone on the contractile activity of Latissimus dorsi muscle isolated in an organ chamber: experimental study in rats.

  Arquivos brasileiros de cardiologia 20020301

• Oral loading with propafenone for conversion of recent-onset atrial fibrillation: a review on in-hospital treatment.

  Drugs 20020101

• [Disclosure of 'Brugada's syndrome' with intravenous propafenone].

  Archivos de cardiologia de Mexico 20020101

• Exercise-induced bidirectional ventricular tachycardia with alternating right and left bundle branch block-type patterns--a case report.

  Angiology 20020101

• [Hepatic toxicity of propafenone: a case description].

  Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna 20020101

• [Pharmacological cardioversion of atrial fibrillation with intravenous and oral propafenone].

  Medicina (Kaunas, Lithuania) 20020101

• Chiral metabolism of propafenone in rat hepatic microsomes treated with two inducers.

  World journal of gastroenterology 20011215

• Late-breaking clinical trials at the American Heart Association's scientific sessions 2001.

  Circulation 20011120

• Propafenone modulates potassium channel activities of vascular smooth muscle from rat portal veins.

  The Journal of pharmacology and experimental therapeutics 20011101

• Giant inverted T waves.

  American journal of critical care : an official publication, American Association of Critical-Care Nurses 20011101

• Applications of liquid chromatography-tandem mass spectrometry in drug and biomedical analyses.

  Clinica chimica acta; international journal of clinical chemistry 20011101

• [Liver function test impairment induced by propafenone in a 73 year old woman].

  Harefuah 20011101

• The effect of propafenone on premature ventricular contractions (PVC): an analysis based on heart rate dependency of PVCs.

  Japanese heart journal 20011101

• Non-sustained ventricular tachycardia due to low-dose orphenadrine.

  The American journal of medicine 20011001

• Stereoselective metabolism of propafenone by human liver CYP3A4 expressed in transgenic Chinese hamster CHL cells lines.

  Acta pharmacologica Sinica 20011001

• Simultaneous modeling of pharmacokinetics and pharmacodynamics of propafenone in healthy subjects.

  Acta pharmacologica Sinica 20011001

• Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation.

  The American journal of cardiology 20010915

• Transient outward current inhibition by propafenone and 5-hydroxypropafenone in cultured neonatal rat ventricular myocytes.

  Journal of cardiovascular pharmacology 20010901

• Visual compatibility of sodium nitroprusside with other injectable medications given to pediatric patients.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20010801

• [Comparison of efficacy, safety and cost-effectiveness of intravenous versus oral propafenone in paroxysmal atrial fibrillation].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010801

• Efficacy and safety of dofetilide in the prevention of symptomatic episodes of paroxysmal supraventricular tachycardia: a 6-month double-blind comparison with propafenone and placebo.

  American heart journal 20010701

• The influence of CYP2D6 polymorphism on the antiarrhythmic efficacy of propafenone in patients with paroxysmal atrial fibrillation during 3 months propafenone prophylactic treatment.

  International journal of clinical pharmacology and therapeutics 20010701

• Altered values of heart rate variability in patients with relapse of atrial fibrillation during the first week after electrical cardioversion: preliminary data.

  Italian heart journal : official journal of the Italian Federation of Cardiology 20010601

• Class IC antiarrhythmic drug induced atrial flutter: electrocardiographic and electrophysiological findings and their importance for long term outcome after right atrial isthmus ablation.

  Heart (British Cardiac Society) 20010401

• Effects of propafenone on anisotropic conduction properties within the three-dimensional structure of the canine ventricular wall.

  Basic research in cardiology 20010401

• Blocking effects of the antiarrhythmic drug propafenone on the HERG potassium channel.

  Naunyn-Schmiedeberg's archives of pharmacology 20010401

• Electrophysiologic effects and efficacy of intravenous propafenone in terminating atrioventricular reentrant tachycardia in children.

  The American journal of cardiology 20010315

• [Acute cholestatic hepatitis caused by propafenone. Report of a case and review of the literature].

  Recenti progressi in medicina 20010301

• Global distribution of atrial ectopic foci triggering recurrence of atrial tachyarrhythmia after electrical cardioversion of long-standing atrial fibrillation: a bi-atrial basket mapping study.

  Journal of the American College of Cardiology 20010301

• Single oral loading dose of propafenone for pharmacological cardioversion of recent-onset atrial fibrillation.

  Journal of the American College of Cardiology 20010201

• Differential effects of dofetilide, amiodarone, and class lc drugs on left and right atrial refractoriness and left atrial vulnerability in pigs.

  Naunyn-Schmiedeberg's archives of pharmacology 20010201

• Intravenous antiarrhythmic agents.

  Current opinion in cardiology 20010101

• Evaluation of CYP2D6 oxidation of dextromethorphan and propafenone in a Chinese population with atrial fibrillation.

  Journal of clinical pharmacology 20010101

• Efficacy of sequential antiarrhythmic treatment in sinus rhythm maintenance after successful electrocardioversion in patients with chronic non-valvular atrial fibrillation.

  Medical science monitor : international medical journal of experimental and clinical research 20010101

• [Effectiveness and side effects of the treatment with propafenone and flecainide for recent-onset atrial fibrillation].

  Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010101

• Pharmacologic conversion of atrial fibrillation: a systematic review of available evidence.

  Progress in cardiovascular diseases 20010101

• Algorithmic complexity. A new approach of non-linear algorithms for the analysis of atrial signals from multipolar basket catheter.

  Annali dell'Istituto superiore di sanita 20010101

• An organic psychosis due to a venlafaxine-propafenone interaction.

  International journal of psychiatry in medicine 20010101

• Propafenone-induced ataxia: report of three cases.

  The American journal of the medical sciences 20000801

• Propiverine-induced Parkinsonism: a case report and a pharmacokinetic/pharmacodynamic study in mice.

  Pharmaceutical research 20000501

• Orthodromic tachycardia with atrioventricular dissociation: evidence for a nodoventricular (Mahaim) fiber.

  Pacing and clinical electrophysiology : PACE 20000201

• Persistent atrial flutter in patients treated for atrial fibrillation with amiodarone and propafenone: electrophysiologic characteristics, radiofrequency catheter ablation, and risk prediction.

  Journal of cardiovascular electrophysiology 19990901

• Comparison of propafenone versus procainamide for the acute treatment of atrial fibrillation after cardiac surgery.

  The American journal of cardiology 19990801

• Effects of propafenone and 5-hydroxy-propafenone on hKv1.5 channels.

  British journal of pharmacology 19981101

• Atrial flutter with 1:1 atrioventricular conduction caused by propafenone.

  Pacing and clinical electrophysiology : PACE 19981001

• [Circulatory arrest after combined intravenous drugs for the treatment of orthodromic circular tachycardia of Wolff-Parkinson-White syndrome].

  Revista espanola de cardiologia 19970901

• Propafenone for conversion and prophylaxis of atrial fibrillation. Propafenone Atrial Fibrillation Trial Investigators.

  The American journal of cardiology 19970215

• Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group.

  The American journal of cardiology 19960815

• Propafenone versus disopyramide for maintenance of sinus rhythm after electrical cardioversion of chronic atrial fibrillation: a randomized, double-blind study. PRODIS Study Group.

  Cardiovascular drugs and therapy 19960501

• Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial.

  Journal of internal medicine 19960301

• Probable propafenone-induced transient global amnesia.

  The Annals of pharmacotherapy 19950601

• Propafenone-induced peripheral neuropathy.

  Mayo Clinic proceedings 19950501

• [Persistent atrial flutter induced by propafenone (Rytmonorm)].

  Orvosi hetilap 19940814

• Myoclonus associated with propafenone.

  BMJ (Clinical research ed.) 19940108

• Propafenone-induced liver injury: report of a case and review of the literature.

  Gastroenterology 19930501

• Normal left ventricular function does not protect against propafenone-induced incessant ventricular tachycardia.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 19930401

• [Prevention of paroxysmal atrial fibrillation with propafenone after withdrawal of amiodarone because of side effects].

  La Clinica terapeutica 19930401

• Proarrhythmic effects of class Ic drugs.

  Clinical therapeutics 19930101

• Electrophysiological and electropharmacological studies in pre-excitation syndromes: results with propafenone therapy and isoproterenol infusion testing.

  European heart journal 19921101

• Propafenone-induced torsade de pointes: cross-reactivity with quinidine.

  Pacing and clinical electrophysiology : PACE 19911101

• Metoprolol-induced delirium perpetuated by propafenone.

  American family physician 19911001

• Malignant ventricular tachycardia during propafenone treatment in a child with junctional automatic tachycardia: effectiveness of intravenous molar sodium lactate.

  Pacing and clinical electrophysiology : PACE 19910501

• The use of associated propafenone in patients with amiodarone-resistant ventricular tachycardia.

  International journal of cardiology 19910501

• [Hemolytic reaction resulting from propafenone administration].

  Zhonghua nei ke za zhi 19910401

• Exacerbation of myasthenia by propafenone.

  Journal of neurology, neurosurgery, and psychiatry 19910401

• Atrial flutter in patients treated for atrial fibrillation with propafenone.

  The American journal of cardiology 19900915

• Changes in cardiac output determined by continuous-wave Doppler echocardiography during propafenone or mexiletine drug testing.

  The American journal of cardiology 19900215

• [Myoclonic encephalopathy caused by propafenone].

  Therapie 19900101

• Congestive heart failure induced by six of the newer antiarrhythmic drugs.

  Journal of the American College of Cardiology 19891101

• Cardioprotective effects of various class I antiarrhythmic drugs in canine hearts.

  Journal of the American College of Cardiology 19890701

• Symptomatic sinus node dysfunction associated with the use of propafenone.

  The American journal of cardiology 19880901

• Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.

  Klinische Wochenschrift 19871215

• [Intense symptomatic bradycardia caused by sinoauricular block: severe adverse reaction caused by propafenone].

  Medicina clinica 19871010

• Enhanced antiarrhythmic efficacy of propafenone when used in combination with procainamide or quinidine.

  American heart journal 19870901

• [Anti-arrhythmia efficacy of propafenone in children. Apropos of 30 cases].

  Archives des maladies du coeur et des vaisseaux 19870801

• [Fibrillation and atrial flutter. Immediate control and conversion to sinus rhythm with intravenous propafenone].

  Giornale italiano di cardiologia 19870801

• Double-blind study of intravenous propafenone for paroxysmal supraventricular reentrant tachycardia.

  Journal of the American College of Cardiology 19870601

• Myasthenia-like syndrome induced by cardiovascular agents. Report of a case.

  Italian journal of neurological sciences 19870401

• Sustained ventricular tachycardia occurring during propafenone therapy.

  Acta cardiologica 19870101

• Torsade de pointes ventricular tachycardia in a hypothyroid patient treated with propafenone.

  The Canadian journal of cardiology 19870101

• Demonstration of beta adrenoceptor blockade by propafenone hydrochloride: clinical pharmacologic, radioligand binding and adenylate cyclase activation studies.

  The Journal of pharmacology and experimental therapeutics 19840201

• Drug interactions with amiodarone.

  American heart journal 19831001