3471-31-6 | 5-Methoxyindole-3-acetic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$19.00	$14.00
5g	95%	in stock	$84.00	$59.00
10g	95%	in stock	$156.00	$109.00
25g	98%	in stock	$387.00	$271.00
100g	98%	in stock	$1,490.00	$1,043.00

Description

• Catalog Number: AB69374
• Chemical Name: 5-Methoxyindole-3-acetic acid
• CAS Number: 3471-31-6
• Molecular Formula: C11H11NO3
• Molecular Weight: 205.2099
• MDL Number: MFCD00005638
• SMILES: COc1ccc2c(c1)c(c[nH]2)CC(=O)O

Computed Properties

• Complexity: 244
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 1.4

Literature

• Alteration of melatonin secretion in patients with type 2 diabetes and proliferative diabetic retinopathy.

  Clinical ophthalmology (Auckland, N.Z.) 20110101

• Significance of high levels of endogenous melatonin in Mammalian cerebrospinal fluid and in the central nervous system.

  Current neuropharmacology 20100901

• Melatonin metabolism in the central nervous system.

  Current neuropharmacology 20100901

• Melatonin and structurally-related compounds protect synaptosomal membranes from free radical damage.

  International journal of molecular sciences 20100101

• A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan.

  PloS one 20100101

• Effects of naphthalene, beta-naphthoflavone and benzo(a)pyrene on the diurnal and nocturnal indoleamine metabolism and melatonin content in the pineal organ of rainbow trout, Oncorhynchus mykiss.

  Aquatic toxicology (Amsterdam, Netherlands) 20090402

• Melatonin in the skin: synthesis, metabolism and functions.

  Trends in endocrinology and metabolism: TEM 20080101

• Binding of ring-substituted indole-3-acetic acids to human serum albumin.

  Bioorganic & medicinal chemistry 20070701

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• On-line preconcentration techniques in determination of melatonin and its precursors/metabolites using micellar electrokinetic chromatography.

  Journal of chromatography. A 20060203

• Determination of melatonin and its precursors and metabolites using capillary electrophoresis with UV and fluorometric detection.

  Journal of separation science 20051101

• Indoleamines and 5-methoxyindoles in trout pineal organ in vivo: daily changes and influence of photoperiod.

  General and comparative endocrinology 20051001

• Effect of indole-3-acetic acid derivatives on neuroepithelium in rat embryos.

  The Journal of toxicological sciences 20050801

• A foxy intoxication.

  Forensic science international 20050210

• Novel stable fluorophore, 6-methoxy-4-quinolone, with strong fluorescence in wide pH range of aqueous media, and its application as a fluorescent labeling reagent.

  Journal of chromatography. A 20041203

• Peroxynitrite scavenging activity of indole derivatives: interaction of indoles with peroxynitrite.

  Journal of medicinal food 20040101

• Expression of human organic anion transporters in the choroid plexus and their interactions with neurotransmitter metabolites.

  Journal of pharmacological sciences 20031201

• Photoperiod affects amplitude but not duration of in vitro melatonin production in the ruin lizard (Podarcis sicula).

  Journal of biological rhythms 20030201

• Foxy, a designer tryptamine hallucinogen.

  Journal of analytical toxicology 20030101

• Total pineal endocrine substitution therapy (TPEST) as a new neuroendocrine palliative treatment of untreatable metastatic solid tumor patients: a phase II study.

  Neuro endocrinology letters 20030101

• Halogenated indole-3-acetic acids as oxidatively activated prodrugs with potential for targeted cancer therapy.

  Bioorganic & medicinal chemistry letters 20020916

• Demonstration of antifungal and anti-human immunodeficiency virus reverse transcriptase activities of 6-methoxy-2-benzoxazolinone and antibacterial activity of the pineal indole 5-methoxyindole-3-acetic acid.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601

• [Morphofunctional changes in the pineal gland during adaptation to hypothermia].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20011201

• Examination of pineal indoles and 6-methoxy-2-benzoxazolinone for antioxidant and antimicrobial effects.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20011101

• Effect of light on 5-methoxyindole-3-acetic acid in the rat.

  Journal of neural transmission (Vienna, Austria : 1996) 20010101

• Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.

  The Journal of biological chemistry 19990507