3481-09-2 | N-Chlorophthalimide

Packsize	Purity	Availability	Price	Discounted Price
5g	95%	in stock	$10.00	$7.00
10g	95%	in stock	$11.00	$8.00
25g	95%	in stock	$18.00	$13.00
100g	95%	in stock	$58.00	$41.00

Description

• Catalog Number: AI48530
• Chemical Name: N-Chlorophthalimide
• CAS Number: 3481-09-2
• Molecular Formula: C8H4ClNO2
• Molecular Weight: 181.5759
• MDL Number: MFCD00023027
• SMILES: ClN1C(=O)c2c(C1=O)cccc2
• NSC Number: 76078

Computed Properties

• Complexity: 217
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 1.5

Upstream Synthesis Route

N-Chlorophthalimide is a versatile reagent commonly used in chemical synthesis due to its ability to act as a selective chlorinating agent. In organic chemistry, it is widely employed for the introduction of chlorine atoms into various organic compounds.One of the key applications of N-Chlorophthalimide is in the synthesis of aromatic compounds, where it can facilitate the selective chlorination of aromatic rings. This reagent is particularly valuable in the preparation of chlorinated benzenes and related derivatives, which are important building blocks in the production of pharmaceuticals, agrochemicals, and materials science.Additionally, N-Chlorophthalimide is utilized in the synthesis of a variety of heterocyclic compounds, such as chlorinated pyrroles and indoles. These chlorinated heterocycles have diverse applications in medicinal chemistry and materials research, making N-Chlorophthalimide a valuable tool for the preparation of complex organic molecules with tailored properties.Furthermore, N-Chlorophthalimide finds use in the modification of amino acids and peptides, where its selective chlorinating ability can be harnessed to introduce chlorine functionalities at specific sites within these biomolecules. This selective chlorination of amino acid residues can have implications in peptide-based drug design and biological studies.Overall, N-Chlorophthalimide is a versatile reagent with a wide range of applications in chemical synthesis, particularly in the selective chlorination of organic compounds to generate valuable intermediates for various industries.

Literature

• Structural, vibrational and DFT studies on 2-chloro-1H-isoindole-1,3(2H)-dione and 2-methyl-1H-isoindole-1,3(2H)-dione.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091015