35180-01-9 | Chloromethyl isopropyl carbonate

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$6.00	$5.00
100g	98%	in stock	$18.00	$13.00
500g	98%	in stock	$63.00	$45.00

Description

• Catalog Number: AB45731
• Chemical Name: Chloromethyl isopropyl carbonate
• CAS Number: 35180-01-9
• Molecular Formula: C5H9ClO3
• Molecular Weight: 152.5762
• MDL Number: MFCD07375443
• SMILES: ClCOC(=O)OC(C)C

Computed Properties

• Complexity: 92.2
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• XLogP3: 2

Upstream Synthesis Route

Isopropyl chloromethyl carbonate is a versatile chemical reagent commonly used in organic synthesis as a carbonyl-activating agent. It is particularly valued for its ability to selectively protect hydroxyl groups in the presence of other functional groups, making it a valuable tool in the synthesis of complex molecules.One common application of Isopropyl chloromethyl carbonate is in the protection of alcohols during multi-step synthesis reactions. By selectively reacting with the hydroxyl group of an alcohol, Isopropyl chloromethyl carbonate forms a stable carbonate derivative, effectively masking the alcohol functionality. This temporary protection allows chemists to perform subsequent reactions without interfering with the alcohol group, which can be deprotected when needed to reveal the original functionality.Moreover, Isopropyl chloromethyl carbonate can also be utilized as a carbonyl linker in the synthesis of amides and esters. By reacting with amines or alcohols, Isopropyl chloromethyl carbonate facilitates the formation of amide or ester bonds through the reaction of the chloride group with the nucleophilic component. This strategy enables efficient and controlled formation of these important functional groups in various organic molecules.Overall, Isopropyl chloromethyl carbonate serves as a valuable reagent in chemical synthesis, offering chemists a useful tool for selectively modifying and protecting functional groups to facilitate the construction of complex organic compounds.