3588-17-8 | Trans,trans-muconic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$80.00	$56.00
5g	98%	in stock	$297.00	$208.00

Description

• Catalog Number: AB79757
• Chemical Name: Trans,trans-muconic acid
• CAS Number: 3588-17-8
• Molecular Formula: C6H6O4
• Molecular Weight: 142.1094
• MDL Number: MFCD00002702
• SMILES: OC(=O)/C=C/C=C/C(=O)O

Computed Properties

• Complexity: 168
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 2
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 0.2

Literature

• Urinary trans, trans-muconic acid and S-phenylmercapturic acid are indicative of exposure to urban benzene pollution during childhood.

  The Science of the total environment 20121001

• Low occupational exposure to benzene in a petrochemical plant: modulating effect of genetic polymorphisms and smoking habit on the urinary t,t-MA/SPMA ratio.

  Toxicology letters 20120813

• Influence of glutathione S-transferases polymorphisms on biological monitoring of exposure to low doses of benzene.

  Toxicology letters 20120813

• Molecularly imprinted solid-phase extraction and high-performance liquid chromatography with ultraviolet detection for the determination of urinary trans,trans-muconic acid: a comparison with ionic exchange extraction.

  The Analyst 20120521

• Assessment of occupational exposure to benzene, toluene and xylenes in urban and rural female workers.

  Chemosphere 20120501

• Environmental and biological monitoring of benzene in traffic policemen, police drivers and rural outdoor male workers.

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  Indoor air 20120401

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  Environmental health perspectives 20120201

• pH-stat fed-batch process to enhance the production of cis, cis-muconate from benzoate by Pseudomonas putida KT2440-JD1.

  Biotechnology progress 20120101

• Association between environmental exposure to benzene and oxidative damage to nucleic acids in children.

  La Medicina del lavoro 20120101

• Biological monitoring of low-level exposure to benzene.

  La Medicina del lavoro 20120101

• Generation of a catR deficient mutant of P. putida KT2440 that produces cis, cis-muconate from benzoate at high rate and yield.

  Journal of biotechnology 20111210

• Benzenepolycarboxylic acids with potential anti-hemorrhagic properties and structure-activity relationships.

  Bioorganic & medicinal chemistry 20111201

• Biomarkers of internal dose for the assessment of environmental exposure to benzene.

  Journal of environmental monitoring : JEM 20111001

• Trans, trans-muconic acid as a biomarker of occupational exposure to high-level benzene in China.

  Journal of occupational and environmental medicine 20111001

• Selective hydrogenation of trans,trans-muconic acid to adipic acid over a titania-supported rhenium catalyst.

  ChemSusChem 20110822

• A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04.

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• A non-fluorescent derivative from derivatizing trans, trans-muconic acid with 2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate.

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• In silico studies with human DNA topoisomerase-II alpha to unravel the mechanism of in vitro genotoxicity of benzene and its metabolites.

  Mutation research 20090210

• Determination of urinary trans, trans-muconic acid reference values in general Tunisian population.

  Annales de biologie clinique 20090101

• Isolation and partial characterization of catechol 1,2-dioxygenase of phenol degrading yeast Candida tropicalis.

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• Biological monitoring of low benzene exposure in Italian traffic policemen.

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• Reference values of urinary trans,trans-muconic acid: Italian Multicentric Study.

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• Redetermination of trans-beta-hydromuconic acid.

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  Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20080601

• Validation of an HPLC/MS/MS method with isotopic dilution for quantitative determination of trans,trans-muconic acid in urine samples of workers exposed to low benzene concentrations.

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• Study of factors which negatively affect expression of the phenol degradation operon pheBA in Pseudomonas putida.

  Microbiology (Reading, England) 20070601

• Comparison of benzene exposure in drivers and petrol stations workers by urinary trans,trans-muconic acid in west of Iran.

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• Distinct effector-binding sites enable synergistic transcriptional activation by BenM, a LysR-type regulator.

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• A battery of DNA effect biomarkers to evaluate environmental exposure of Flemish adolescents.

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  Giornale italiano di medicina del lavoro ed ergonomia 20070101

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• The key role of chlorocatechol 1,2-dioxygenase in phytoremoval and degradation of catechol by transgenic Arabidopsis.

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  International immunopharmacology 20050901

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• High-pressure liquid chromatographic-mass spectrometric determination of sorbic acid in urine: verification of formation of trans,trans-muconic acid.

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  Yonsei medical journal 20050430

• A sensitive liquid chromatographic method for the spectrophotometric determination of urinary trans,trans-muconic acid.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050425

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  The Southeast Asian journal of tropical medicine and public health 20040901

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  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20040101

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  Rapid communications in mass spectrometry : RCM 20040101

• An electrospray ionization tandem mass spectrometry based system with an online dual-loop cleanup device for simultaneous quantitation of urinary benzene exposure biomarkers trans,trans-muconic acid and S-phenylmercapturic acid.

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  Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101

• Urinary 1-hydroxypyrene and t,t-muconic acid as biomarkers of exposure to environmental pollutants in two areas in Italy (EPIC-Florence and Ragusa).

  Tumori 20030101

• A note on urine trans, trans muconic acid level among a sample of Thai police: implication for an occupational health issue.

  The Yale journal of biology and medicine 20030101

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  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021201

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  The Southeast Asian journal of tropical medicine and public health 20021201

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  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20010601

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