359-13-7 | 2,2-Difluoroethanol

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$9.00	$6.00
25g	98%	in stock	$20.00	$14.00
100g	98%	in stock	$56.00	$39.00

Description

• Catalog Number: AB43544
• Chemical Name: 2,2-Difluoroethanol
• CAS Number: 359-13-7
• Molecular Formula: C2H4F2O
• Molecular Weight: 82.0494
• MDL Number: MFCD00042248
• SMILES: OCC(F)F

Computed Properties

• Complexity: 21.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.4

Upstream Synthesis Route

2,2-Difluoroethanol is a versatile compound that finds extensive application in chemical synthesis. As a primary alcohol with two fluorine atoms attached to the alpha carbon, it serves as a valuable building block for various reactions in organic chemistry. In chemical synthesis, 2,2-Difluoroethanol can be utilized as a solvent for reactions involving sensitive or reactive compounds. Its unique properties, such as high polarity and the presence of fluorine atoms, make it a suitable medium for promoting specific chemical transformations, especially in the presence of fluorine-sensitive functional groups.Furthermore, 2,2-Difluoroethanol can act as a precursor for the introduction of fluorine atoms into organic molecules. Through functional group transformations and derivatization reactions, chemists can incorporate the difluoroethyl moiety into target compounds, thereby enhancing their chemical and/or biological properties. This strategic use of 2,2-Difluoroethanol enables the synthesis of fluorinated organic molecules with diverse applications in medicinal chemistry, materials science, and other fields. Overall, the unique properties and reactivity of 2,2-Difluoroethanol make it a valuable tool for chemists seeking to design and synthesize novel fluorinated compounds with specific functionalities and applications.

Literature

• Intermolecular interactions, disorder and twinning in ciprofloxacin-2,2-difluoroethanol (2/3) and ciprofloxacin-water (3/14.5).

  Acta crystallographica. Section C, Crystal structure communications 20110301

• Influence of fluorine atoms and aromatic rings on the acidity of ethanol.

  The journal of physical chemistry. A 20091008