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Effect of tetrahydrocurcumin on the profiles of drug-metabolizing enzymes induced by a high fat and high fructose diet in mice.
Chemico-biological interactions 20150905
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Tetrahydrocurcumin exerts protective effect on vincristine induced neuropathy: Behavioral, biochemical, neurophysiological and histological evidence.
Chemico-biological interactions 20150805
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Ameliorative efficacy of tetrahydrocurcumin against arsenic induced oxidative damage, dyslipidemia and hepatic mitochondrial toxicity in rats.
Chemico-biological interactions 20150625
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Tetrahydrocurcumin protects against cadmium-induced hypertension, raised arterial stiffness and vascular remodeling in mice.
PloS one 20140101
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Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributes.
Food chemistry 20130115
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Tissue distribution of (Lipocurc™) liposomal curcumin and tetrahydrocurcumin following two- and eight-hour infusions in Beagle dogs.
Anticancer research 20121001
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Infusion pharmacokinetics of Lipocurc™ (liposomal curcumin) and its metabolite tetrahydrocurcumin in Beagle dogs.
Anticancer research 20121001
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Tetrahydrocurcumin ameliorates homocysteinylated cytochrome-c mediated autophagy in hyperhomocysteinemia mice after cerebral ischemia.
Journal of molecular neuroscience : MN 20120501
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Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency.
Hypertension research : official journal of the Japanese Society of Hypertension 20120401
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Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha.
Natural product communications 20120401
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Tetrahydrocurcumin is more effective than curcumin in preventing azoxymethane-induced colon carcinogenesis.
Molecular nutrition & food research 20111201
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Tetrahydrocurcumin, a major metabolite of curcumin, induced autophagic cell death through coordinative modulation of PI3K/Akt-mTOR and MAPK signaling pathways in human leukemia HL-60 cells.
Molecular nutrition & food research 20111101
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Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.
Aging 20111101
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Bioactive antioxidant mixtures promote proliferation and migration on human oral fibroblasts.
Archives of oral biology 20110801
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Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension.
Naunyn-Schmiedeberg's archives of pharmacology 20110501
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Controlled release of oral tetrahydrocurcumin from a novel self-emulsifying floating drug delivery system (SEFDDS).
AAPS PharmSciTech 20110301
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In vitro inhibitory effect of tetrahydrocurcuminoids on Fusarium proliferatum growth and fumonisin B₁ biosynthesis.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20110201
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Tetrahydrocurcumin confers protection against amyloid β-induced toxicity.
Neuroreport 20110105
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Antihyperlipidemic effect of chlorogenic acid and tetrahydrocurcumin in rats subjected to diabetogenic agents.
Chemico-biological interactions 20101205
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Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells.
Journal of periodontology 20101101
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Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity.
European journal of medicinal chemistry 20101001
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Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study.
Photomedicine and laser surgery 20101001
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Comparative and combined effect of chlorogenic acid and tetrahydrocurcumin on antioxidant disparities in chemical induced experimental diabetes.
Molecular and cellular biochemistry 20100801
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Curcuminoids activate p38 MAP kinases and promote UVB-dependent signalling in keratinocytes.
Experimental dermatology 20100601
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Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species.
European journal of medicinal chemistry 20100301
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Combined treatment of tetrahydrocurcumin and chlorogenic acid exerts potential antihyperglycemic effect on streptozotocin-nicotinamide-induced diabetic rats.
General physiology and biophysics 20100301
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Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts.
Methods in molecular biology (Clifton, N.J.) 20100101
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Optimized turmeric extracts have potent anti-amyloidogenic effects.
Current Alzheimer research 20091201
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Curcumin is a potent DNA hypomethylation agent.
Bioorganic & medicinal chemistry letters 20090201
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Cardioprotective effect of tetrahydrocurcumin and rutin on lipid peroxides and antioxidants in experimentally induced myocardial infarction in rats.
Die Pharmazie 20090201
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Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.
Biochemical and biophysical research communications 20081226
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Tetrahydrocurcumin inhibits HT1080 cell migration and invasion via downregulation of MMPs and uPA.
Acta pharmacologica Sinica 20080701
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Anti-cancer and anti-angiogenic effects of curcumin and tetrahydrocurcumin on implanted hepatocellular carcinoma in nude mice.
World journal of gastroenterology 20080407
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Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080401
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Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice.
Inflammopharmacology 20080401
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Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes.
Journal of biosciences 20080301
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Comparative anti-inflammatory activities of curcumin and tetrahydrocurcumin based on the phenolic O-H bond dissociation enthalpy, ionization potential and quantum chemical descriptor.
Anticancer research 20080101
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Influence of tetrahydrocurcumin on tail tendon collagen contents and its properties in rats with streptozotocin-nicotinamide-induced type 2 diabetes.
Fundamental & clinical pharmacology 20071201
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The effects of tetrahydrocurcumin and green tea polyphenol on the survival of male C57BL/6 mice.
Biogerontology 20071001
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Influence of tetrahydrocurcumin on hepatic and renal functional markers and protein levels in experimental type 2 diabetic rats.
Basic & clinical pharmacology & toxicology 20071001
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Influence of tetrahydrocurcumin on erythrocyte membrane bound enzymes and antioxidant status in experimental type 2 diabetic rats.
Journal of ethnopharmacology 20070925
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Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.
Carcinogenesis 20070801
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Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells.
Experimental & molecular medicine 20070630
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The study of human skin irritation of a novel herbal skin care product and ingredients by human single closed patch testing.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070601
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Tetrahydrocurcumin prevents brain lipid peroxidation in streptozotocin-induced diabetic rats.
Journal of medicinal food 20070601
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Changes in glycoprotein components in streptozotocin--nicotinamide induced type 2 diabetes: influence of tetrahydrocurcumin from Curcuma longa.
Plant foods for human nutrition (Dordrecht, Netherlands) 20070301
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Curcumin induces pro-apoptotic endoplasmic reticulum stress in human leukemia HL-60 cells.
Biochemical and biophysical research communications 20070223
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Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.
Molecular and cellular biochemistry 20070201
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Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives.
Biological & pharmaceutical bulletin 20070101
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Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase.
Anticancer research 20070101
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Antihyperlipidemic effect of curcumin and tetrahydrocurcumin in experimental type 2 diabetic rats.
Renal failure 20070101
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Comparative radical-scavenging activity of curcumin and tetrahydrocurcumin with thiols as measured by the induction period method.
In vivo (Athens, Greece) 20070101
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Tetrahydrocurcumin: effect on chloroquine-mediated oxidative damage in rat kidney.
Basic & clinical pharmacology & toxicology 20061101
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Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats.
Life sciences 20060927
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Effect of tetrahydrocurcumin on lipid peroxidation and lipids in streptozotocin-nicotinamide-induced diabetic rats.
Basic & clinical pharmacology & toxicology 20060801
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Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin.
Journal of pharmaceutical and biomedical analysis 20060224
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Effect of tetrahydrocurcumin on plasma antioxidants in streptozotocin-nicotinamide experimental diabetes.
Journal of basic and clinical physiology and pharmacology 20060101
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Tetrahydrocurcumin in plasma and urine: quantitation by high performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925
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Relationship between intracellular ROS production and membrane mobility in curcumin- and tetrahydrocurcumin-treated human gingival fibroblasts and human submandibular gland carcinoma cells.
Oral diseases 20050701
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Protective role of tetrahydrocurcumin (THC) an active principle of turmeric on chloroquine induced hepatotoxicity in rats.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20050430
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Effect of tetrahydrocurcumin on erythromycin estolate-induced lipid peroxidation in rats.
Journal of basic and clinical physiology and pharmacology 20050101
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Effect of tetrahydrocurcumin on blood glucose, plasma insulin and hepatic key enzymes in streptozotocin induced diabetic rats.
Journal of basic and clinical physiology and pharmacology 20050101
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Hydrogen-bonding and C-H...pi interactions in 1,7-bis(4-hydroxy-3-methoxyphenyl)heptane-3,5-dione (tetrahydrocurcumin).
Acta crystallographica. Section C, Crystal structure communications 20040801
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Interventions in aging and age-associated pathologies by means of nutritional approaches.
Annals of the New York Academy of Sciences 20040601
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Protective role of tetrahydrocurcumin against erythromycin estolate-induced hepatotoxicity.
Pharmacological research 20040501
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Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.
Biochemical and biophysical research communications 20031010
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Contact allergy to tetrahydrocurcumin.
Contact dermatitis 20030401
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Studies on the role of some synthetic curcuminoid derivatives in the inhibition of tumour specific angiogenesis.
Journal of experimental & clinical cancer research : CR 20030301
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The protective effects of tetrahydrocurcumin on oxidative stress in cholesterol-fed rabbits.
Journal of atherosclerosis and thrombosis 20020101
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Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.
Journal of medicinal chemistry 19970912
