3621-79-2 | 2-Methyleneglutaric acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$249.00	$175.00
1g	96%	in stock	$510.00	$357.00
5g	96%	in stock	$2,002.00	$1,402.00

Description

• Catalog Number: AD39913
• Chemical Name: 2-Methyleneglutaric acid
• CAS Number: 3621-79-2
• Molecular Formula: C6H8O4
• Molecular Weight: 144.1253
• MDL Number: MFCD06208028
• SMILES: OC(=O)CCC(=C)C(=O)O
• NSC Number: 21369

Computed Properties

• Complexity: 171
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.1

Literature

• Role of calcium in acclimation of the cyanobacterium Synechococcus elongatus PCC 7942 to nitrogen starvation.

  Microbiology (Reading, England) 20090101

• Comparative genomic analyses of nickel, cobalt and vitamin B12 utilization.

  BMC genomics 20090101

• Competitive inhibition of glutamate dehydrogenase reaction.

  FEBS letters 20070612

• Studying the signaling role of 2-oxoglutaric acid using analogs that mimic the ketone and ketal forms of 2-oxoglutaric acid.

  Chemistry & biology 20060801

• Regioselective synthesis of alpha-methyl 2-methyleneglutarate via a novel lactonization-elimination rearrangement.

  The Journal of organic chemistry 20060106

• Searching for intermediates in the carbon skeleton rearrangement of 2-methyleneglutarate to (R)-3-methylitaconate catalyzed by coenzyme B12-dependent 2-methyleneglutarate mutase from Eubacterium barkeri.

  Biochemistry 20050809

• Kinetic results implicating a polar radical reaction pathway in the rearrangement catalyzed by alpha-methyleneglutarate mutase.

  Journal of the American Chemical Society 20030409

• Rotation of the exo-methylene group of (R)-3-methylitaconate catalyzed by coenzyme B(12)-dependent 2-methyleneglutarate mutase from Eubacterium barkeri.

  Journal of the American Chemical Society 20021127

• A novel reaction between adenosylcobalamin and 2-methyleneglutarate catalyzed by glutamate mutase.

  Biochemistry 20020305

• Interconversion of (S)-glutamate and (2S,3S)-3-methylaspartate: a distinctive B(12)-dependent carbon-skeleton rearrangement.

  Journal of the American Chemical Society 20010822