368-48-9 | 2-(Trifluoromethyl)pyridine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$20.00	$14.00
5g	95%	in stock	$25.00	$17.00
25g	95%	in stock	$49.00	$35.00
500g	95%	in stock	$853.00	$597.00

Description

• Catalog Number: AF56884
• Chemical Name: 2-(Trifluoromethyl)pyridine
• CAS Number: 368-48-9
• Molecular Formula: C6H4F3N
• Molecular Weight: 147.0979
• MDL Number: MFCD02183562
• SMILES: FC(c1ccccn1)(F)F

Computed Properties

• Complexity: 110
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• XLogP3: 1.8

Literature

• A novel halogen bond and a better-known hydrogen bond cooperation of neonicotinoid and insect nicotinic acetylcholine receptor recognition.

  Journal of molecular modeling 20120801

• Synthesis of N-(trifluoromethyl-2-pyridinyl)arenesulfonamides as an inhibitor of secretory phospholipase A₂.

  Chemical & pharmaceutical bulletin 20110101

• A new strategy for the synthesis of poly-substituted 3-H, 3-fluoro, or 3-trifluoromethyl pyridines via the tandem C-F bond cleavage protocol.

  Organic letters 20101001

• Synthesis and evaluation of anticancer activity of 2-arylamino-6-trifluoromethyl-3-(hydrazonocarbonyl)pyridines.

  Bioorganic & medicinal chemistry 20090901

• Synthesis and evaluation of antitumoral activity of ester and amide derivatives of 2-arylamino-6-trifluoromethyl-3-pyridinecarboxylic acids.

  Bioorganic & medicinal chemistry 20080301

• Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method.

  Proteome science 20080101

• Substituted benzylamino-6-(trifluoromethyl)pyrimidin-4(1H)-ones: a novel class of selective human A-FABP inhibitors.

  Bioorganic & medicinal chemistry letters 20040906

• Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20040901

• Synthesis of new 2-arylamino-6-trifluoromethylpyridine-3-carboxylic acid derivatives and investigation of their analgesic activity.

  Bioorganic & medicinal chemistry 20040801