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Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity.
Chemical research in toxicology 20180521
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TRPM8 activation attenuates inflammatory responses in mouse models of colitis.
Proceedings of the National Academy of Sciences of the United States of America 20130430
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Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice.
Toxicology letters 20130313
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TRPA1-like channels enhance glycinergic transmission in medullary dorsal horn neurons.
Journal of neurochemistry 20120801
-
Menthol suppresses nicotinic acetylcholine receptor functioning in sensory neurons via allosteric modulation.
Chemical senses 20120601
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Lumbar intervertebral disc degeneration associated with axial and radiating low back pain in ageing SPARC-null mice.
Pain 20120601
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Blockade of TRPM8 activity reduces the invasion potential of oral squamous carcinoma cell lines.
International journal of oncology 20120501
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Modulation of thermoreceptor TRPM8 by cooling compounds.
ACS chemical neuroscience 20120418
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Transient receptor potential vanilloid-1 (TRPV1) is a mediator of lung toxicity for coal fly ash particulate material.
Molecular pharmacology 20120301
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Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists.
Journal of medicinal chemistry 20120223
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Effects of antagonists and heat on TRPM8 channel currents in dorsal root ganglion neuron activated by nociceptive cold stress and menthol.
Neurochemical research 20120201
-
Supercooling agent icilin blocks a warmth-sensing ion channel TRPV3.
TheScientificWorldJournal 20120101
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CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch.
PloS one 20120101
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The effects of magnetite (Fe₃O₄) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH₃) cells and in RAW 264.7 macrophages.
International journal of nanomedicine 20120101
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The Role of TRP Proteins in Mast Cells.
Frontiers in immunology 20120101
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Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells.
PloS one 20120101
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Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system.
Pharmacology & therapeutics 20110701
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A novel role for TRPM8 in visceral afferent function.
Pain 20110701
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TRPM8 in mouse sperm detects temperature changes and may influence the acrosome reaction.
Journal of cellular physiology 20110601
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The cannabinoid WIN 55,212-2-mediated protection of dentate gyrus granule cells is driven by CB1 receptors and modulated by TRPA1 and Cav 2.2 channels.
Hippocampus 20110501
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Properties and therapeutic potential of transient receptor potential channels with putative roles in adversity: focus on TRPC5, TRPM2 and TRPA1.
Current drug targets 20110501
-
Characterization of TRPM8-like channels activated by the cooling agent icilin in the macrophage cell line RAW 264.7.
The Journal of membrane biology 20110501
-
Icilin-evoked behavioral stimulation is attenuated by alpha₂-adrenoceptor activation.
Brain research 20110412
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Icilin induces G1 arrest through activating JNK and p38 kinase in a TRPM8-independent manner.
Biochemical and biophysical research communications 20110304
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Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Journal of medicinal chemistry 20110113
-
The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.
The Biochemical journal 20110101
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Pharmacological and functional properties of TRPM8 channels in prostate tumor cells.
Pflugers Archiv : European journal of physiology 20110101
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TRPM8 and Nav1.8 sodium channels are required for transthyretin-induced calcium influx in growth cones of small-diameter TrkA-positive sensory neurons.
Molecular neurodegeneration 20110101
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The transient receptor potential family of ion channels.
Genome biology 20110101
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Cooling-sensitive TRPM8 is thermostat of skin temperature against cooling.
PloS one 20110101
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Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice.
Molecular pain 20110101
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Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines.
Arthritis research & therapy 20110101
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Sensory properties of menthol and smoking topography.
Tobacco induced diseases 20110101
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TRPM8 biology and medicinal chemistry.
Current topics in medicinal chemistry 20110101
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Activation of TRPA1 by membrane permeable local anesthetics.
Molecular pain 20110101
-
Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.
PloS one 20110101
-
Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain.
BMC neuroscience 20110101
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[Comparative effects of menthol and icilin on the induced contraction of the smooth muscles of the vas deferens of normal and castrated rats].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101
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Chronic treatment with NGF induces spontaneous fluctuations of intracellular Ca(2+) in icilin-sensitive dorsal root ganglion neurons of the rat.
The Journal of veterinary medical science 20101201
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Expression of transient receptor potential channel vanilloid (TRPV) 1–4, melastin (TRPM) 5 and 8, and ankyrin (TRPA1) in the normal and methimazole-treated mouse olfactory epithelium.
Acta oto-laryngologica 20101101
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Inhibition of the cardiac L-type calcium channel current by the TRPM8 agonist, (-)-menthol.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20101001
-
Gating of transient receptor potential melastatin 8 (TRPM8) channels activated by cold and chemical agonists in planar lipid bilayers.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100915
-
Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.
The Journal of biological chemistry 20100827
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TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo.
Pain 20100801
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Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
Journal of medicinal chemistry 20100722
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Intact cutaneous C fibre afferent properties in mechanical and cold neuropathic allodynia.
European journal of pain (London, England) 20100701
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Grueneberg ganglion neurons are finely tuned cold sensors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20100602
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(-)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels.
Bioorganic & medicinal chemistry letters 20100501
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Modulation of the cold-activated cation channel TRPM8 by surface charge screening.
The Journal of physiology 20100115
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Amiloride-sensitive channels are a major contributor to mechanotransduction in mammalian muscle spindles.
The Journal of physiology 20100101
-
The roles of iPLA2, TRPM8 and TRPA1 in chemically induced cold hypersensitivity.
Molecular pain 20100101
-
Estrogen regulation of TRPM8 expression in breast cancer cells.
BMC cancer 20100101
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Characterization of selective TRPM8 ligands and their structure activity response (S.A.R) relationship.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101
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Dissociation of μ- and δ-opioid inhibition of glutamatergic synaptic transmission in superficial dorsal horn.
Molecular pain 20100101
-
Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons.
Molecular pain 20100101
-
Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle.
Journal of the peripheral nervous system : JPNS 20091201
-
Non-neuronal expression of transient receptor potential type A1 (TRPA1) in human skin.
The Journal of investigative dermatology 20090901
-
Letter to the editor: 'Is menthol- or icilin-induced vasodilation mediated by the activation of TRPM8?'.
American journal of physiology. Heart and circulatory physiology 20090801
-
Involvement of increased expression of transient receptor potential melastatin 8 in oxaliplatin-induced cold allodynia in mice.
Neuroscience letters 20090717
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Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone.
American journal of physiology. Heart and circulatory physiology 20090601
-
Primary afferents with TRPM8 and TRPA1 profiles target distinct subpopulations of rat superficial dorsal horn neurones.
British journal of pharmacology 20090601
-
Dose-dependent effects of icilin on thermal preference in the hindpaw and face of rats.
The journal of pain : official journal of the American Pain Society 20090601
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Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features.
Biochimica et biophysica acta 20090501
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Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production.
Pharmacology, biochemistry, and behavior 20090501
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Lipid raft segregation modulates TRPM8 channel activity.
The Journal of biological chemistry 20090403
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Adult rat odontoblasts lack noxious thermal sensitivity.
Journal of dental research 20090401
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Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens.
Bioorganic & medicinal chemistry 20090215
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Inhibition of TRPM8 by icilin distinct from desensitization induced by menthol and menthol derivatives.
The Journal of biological chemistry 20090213
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Pore dilation occurs in TRPA1 but not in TRPM8 channels.
Molecular pain 20090101
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Inorganic polyphosphate modulates TRPM8 channels.
PloS one 20090101
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Evolution of thermal response properties in a cold-activated TRP channel.
PloS one 20090101
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Tumor necrosis factor-alpha (TNF-alpha) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes.
Molecular pain 20090101
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Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels.
Molecular pain 20090101
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[Modulation of the smooth muscle contractions of the rat vas deferens by TRPM8 channel agonist menthol].
Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101
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Impairment by allyl isothiocyanate of gastric epithelial wound repair through inhibition of ion transporters.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20081201
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Inhibition by the cold receptor agonists menthol and icilin of airway smooth muscle contraction.
Pulmonary pharmacology & therapeutics 20081001
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Menthol derivative WS-12 selectively activates transient receptor potential melastatin-8 (TRPM8) ion channels.
Pakistan journal of pharmaceutical sciences 20081001
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TRPA1 channels mediate cold temperature sensing in mammalian vagal sensory neurons: pharmacological and genetic evidence.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080730
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Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain.
Brain research 20080618
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Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.
The Journal of pharmacology and experimental therapeutics 20080601
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ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1.
Current neuropharmacology 20080301
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Partial restoration of mutant enzyme homeostasis in three distinct lysosomal storage disease cell lines by altering calcium homeostasis.
PLoS biology 20080201
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Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation.
European journal of pharmacology 20080114
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Molecular and cellular limits to somatosensory specificity.
Molecular pain 20080101
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Citral sensing by Transient [corrected] receptor potential channels in dorsal root ganglion neurons.
PloS one 20080101
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HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity.
Molecular pain 20080101
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Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine.
European journal of pharmacology 20071208
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Characterisation of TRPM8 as a pharmacophore receptor.
Cell calcium 20071201
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Differential behavioral effect of the TRPM8/TRPA1 channel agonist icilin (AG-3-5).
European journal of pharmacology 20071201
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Plasticity in intact A delta- and C-fibers contributes to cold hypersensitivity in neuropathic rats.
Neuroscience 20071130
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Impairment by activation of TRPA1 of gastric epithelial restitution in a wound model using RGM1 cell monolayer.
Inflammopharmacology 20071001
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A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation.
Neuroscience 20070824
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Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids.
Experimental cell research 20070515
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Transient receptor potential channel A1 is directly gated by calcium ions.
The Journal of biological chemistry 20070504
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TRPM8 is required for cold sensation in mice.
Neuron 20070503
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Attenuated cold sensitivity in TRPM8 null mice.
Neuron 20070503
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Modulation of the cold-activated channel TRPM8 by lysophospholipids and polyunsaturated fatty acids.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20070321
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Prospects for prostate cancer imaging and therapy using high-affinity TRPM8 activators.
Cell calcium 20070301
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Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum.
Neuropharmacology 20070301
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TRPM8-independent menthol-induced Ca2+ release from endoplasmic reticulum and Golgi.
The Journal of biological chemistry 20070202
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Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines.
Nature 20070201
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Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells.
Neuroendocrinology 20070101
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Mice left out in the cold: commentary on the phenotype of TRPM8-nulls.
Molecular pain 20070101
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Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists.
Molecular pain 20070101
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The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif.
The Journal of biological chemistry 20061208
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Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats.
European journal of pharmacology 20061010
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Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes.
American journal of physiology. Cell physiology 20060901
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Analgesia mediated by the TRPM8 cold receptor in chronic neuropathic pain.
Current biology : CB 20060822
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Functional expression of thermo-transient receptor potential channels in dental primary afferent neurons: implication for tooth pain.
The Journal of biological chemistry 20060623
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Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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Icilin evokes a dose- and time-dependent increase in glutamate within the dorsal striatum of rats.
Amino acids 20060501
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High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol.
Nature neuroscience 20060401
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Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
European journal of pharmacology 20060113
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Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations.
BMC urology 20060101
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Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing.
BMC neuroscience 20060101
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Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells.
The Journal of biological chemistry 20051125
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Icilin activates the delta-subunit of the human epithelial Na+ channel.
Molecular pharmacology 20051001
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Nociceptor and hair cell transducer properties of TRPA1, a channel for pain and hearing.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
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EGF suppresses hydrogen peroxide induced Ca2+ influx by inhibiting L-type channel activity in cultured human corneal endothelial cells.
Experimental eye research 20050201
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How cold is it? TRPM8 and TRPA1 in the molecular logic of cold sensation.
Molecular pain 20050101
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Two populations of cold-sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor.
The European journal of neuroscience 20041101
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The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel.
Neuron 20040916
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TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH.
The Journal of neuroscience : the official journal of the Society for Neuroscience 20040609
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Thermosensitive transient receptor potential channels in vagal afferent neurons of the mouse.
American journal of physiology. Gastrointestinal and liver physiology 20040601
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Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay.
British journal of pharmacology 20040201
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ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures.
Cell 20030321
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Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
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A TRP channel that senses cold stimuli and menthol.
Cell 20020308
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Identification of a cold receptor reveals a general role for TRP channels in thermosensation.
Nature 20020307
