370-86-5 | Fccp

Packsize	Purity	Availability	Price	Discounted Price
5mg	96%	in stock	$25.00	$18.00
10mg	96%	in stock	$33.00	$23.00
50mg	96%	in stock	$65.00	$46.00
250mg	96%	in stock	$106.00	$75.00
1g	96%	in stock	$251.00	$176.00
5g	96%	in stock	$760.00	$532.00

Description

• Catalog Number: AI68671
• Chemical Name: Fccp
• CAS Number: 370-86-5
• Molecular Formula: C10H5F3N4O
• Molecular Weight: 254.1681
• MDL Number: MFCD00009699
• SMILES: N#CC(=NNc1ccc(cc1)OC(F)(F)F)C#N

Computed Properties

• Complexity: 388
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 3.7

Literature

• Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine.

  Molecular medicine (Cambridge, Mass.) 20160101

• BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria.

  Autophagy 20140601

• Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by anchor kinase A mitochondrial proteins.

  Journal of cellular biochemistry 20121201

• Effect of chronic sleep restriction and aging on calcium signaling and apoptosis in the hippocampus of young and aged animals.

  Progress in neuro-psychopharmacology & biological psychiatry 20121001

• Neuroprotection by lowering cholesterol: a decrease in membrane cholesterol content reduces transporter-mediated glutamate release from brain nerve terminals.

  Biochimica et biophysica acta 20121001

• Structures and mechanisms of antitumor agents: xestoquinones uncouple cellular respiration and disrupt HIF signaling in human breast tumor cells.

  Journal of natural products 20120928

• Induction of the mitochondrial permeability transition (MPT) by micromolar iron: liberation of calcium is more important than NAD(P)H oxidation.

  Biochimica et biophysica acta 20120901

• Alterations in bioenergetic function induced by Parkinson's disease mimetic compounds: lack of correlation with superoxide generation.

  Journal of neurochemistry 20120901

• Mitochondrial free [Ca(2+)] dynamics measured with a novel low-Ca(2+) affinity aequorin probe.

  The Biochemical journal 20120801

• The P2X7 receptor is a key modulator of aerobic glycolysis.

  Cell death & disease 20120801

• Interventricular heterogeneity as a substrate for arrhythmogenesis of decoupled mitochondria during ischemia in the whole heart.

  American journal of physiology. Heart and circulatory physiology 20120715

• Cytotoxicity of a mitochondriotropic quercetin derivative: mechanisms.

  Biochimica et biophysica acta 20120701

• The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis.

  The Journal of pharmacology and experimental therapeutics 20120701

• Simplified bicyclic pyridinol analogues protect mitochondrial function.

  Bioorganic & medicinal chemistry 20120601

• Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction.

  American journal of physiology. Endocrinology and metabolism 20120515

• Electrochemical impedance spectroscopic measurements of FCCP-induced change in membrane permeability of MDCK cells.

  The Analyst 20120507

• 'Mild mitochondrial uncoupling' induced protection against neuronal excitotoxicity requires AMPK activity.

  Biochimica et biophysica acta 20120501

• PK11195 inhibits mitophagy targeting the F1Fo-ATPsynthase in Bcl-2 knock-down cells.

  Current molecular medicine 20120501

• Acute feedback control of astrocytic glycolysis by lactate.

  Glia 20120401

• A simplified hydroethidine method for fast and accurate detection of superoxide production in isolated mitochondria.

  Analytical biochemistry 20120401

• PKCδ and ε regulate the morphological integrity of the ER-Golgi intermediate compartment (ERGIC) but not the anterograde and retrograde transports via the Golgi apparatus.

  Biochimica et biophysica acta 20120401

• Mitochondrial Ca(2+) mobilization is a key element in olfactory signaling.

  Nature neuroscience 20120325

• Measuring mitochondrial respiration in intact single muscle fibers.

  American journal of physiology. Regulatory, integrative and comparative physiology 20120315

• Mitochondrial calpain 10 is degraded by Lon protease after oxidant injury.

  Archives of biochemistry and biophysics 20120115

• Redox state-dependent aggregation of mitochondria induced by cytochrome c.

  Molecular and cellular biochemistry 20120101

• A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets.

  PloS one 20120101

• Mitochondrial uncouplers inhibit hepatic stellate cell activation.

  BMC gastroenterology 20120101

• Mitochondrial involvement in carbachol-induced intracellular Ca2+ mobilization and contraction in rat gastric smooth muscle.

  Life sciences 20111121

• Comparative bioenergetic assessment of transformed cells using a cell energy budget platform.

  Integrative biology : quantitative biosciences from nano to macro 20111101

• Cytoskeleton proteins F-actin and tubulin distribution and interaction with mitochondria in the granulosa cells surrounding stage III zebrafish (Danio rerio) oocytes.

  Theriogenology 20111001

• Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.

  Nature cell biology 20111001

• Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂.

  Journal of neurochemistry 20110701

• Control of hydrogen photoproduction by the proton gradient generated by cyclic electron flow in Chlamydomonas reinhardtii.

  The Plant cell 20110701

• Linking energy metabolism to dysfunctions in mitochondrial respiration--a metabolomics in vitro approach.

  Toxicology letters 20110624

• High-mobility group box 1 is essential for mitochondrial quality control.

  Cell metabolism 20110608

• Changes in mitochondrial redox state, membrane potential and calcium precede mitochondrial dysfunction in doxorubicin-induced cell death.

  Biochimica et biophysica acta 20110601

• Hydrogen sulphide inhibits carbachol-induced contractile responses in β-escin permeabilized guinea-pig taenia caecum.

  European journal of pharmacology 20110511

• Impaired spare respiratory capacity in cortical synaptosomes from Sod2 null mice.

  Free radical biology & medicine 20110401

• Intracellular glutathione levels are involved in carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone-induced apoptosis in As4.1 juxtaglomerular cells.

  International journal of molecular medicine 20110401

• Apoptotic microtubule network organization and maintenance depend on high cellular ATP levels and energized mitochondria.

  Apoptosis : an international journal on programmed cell death 20110401

• Accumulation of dodecyltriphenylphosphonium in mitochondria induces their swelling and ROS-dependent growth inhibition in yeast.

  Journal of bioenergetics and biomembranes 20110401

• Membrane potential is involved in regulation of photosynthetic reactions in the marine diatom Thalassiosira weissflogii.

  Journal of photochemistry and photobiology. B, Biology 20110207

• Visualization and quantification of endoplasmic reticulum Ca2+ in renal cells using confocal microscopy and Fluo5F.

  Biochemical and biophysical research communications 20110107

• Effect of mitochondrial dysfunction and oxidative stress on endogenous levels of coenzyme Q(10) in human cells.

  Journal of biochemical and molecular toxicology 20110101

• Subcellular localization of hexokinases I and II directs the metabolic fate of glucose.

  PloS one 20110101

• Newly developed Mg2+-selective fluorescent probe enables visualization of Mg2+ dynamics in mitochondria.

  PloS one 20110101

• A predictive ligand-based Bayesian model for human drug-induced liver injury.

  Drug metabolism and disposition: the biological fate of chemicals 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Mitochondrial uncoupling downregulates calsequestrin expression and reduces SR Ca2+ stores in cardiomyocytes.

  Cardiovascular research 20101001

• Permissive role of sphingosine on calcium-dependent endocytosis in chromaffin cells.

  Pflugers Archiv : European journal of physiology 20101001

• Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange.

  Biochimica et biophysica acta 20100901

• Mitochondrial dysfunction in Caenorhabditis elegans causes metabolic restructuring, but this is not linked to longevity.

  Mechanisms of ageing and development 20100901

• Attenuation of the hypoxia-induced protein kinase Cdelta interaction with the 'd' subunit of F1Fo-ATP synthase in neonatal cardiac myocytes: implications for energy preservation and survival.

  The Biochemical journal 20100715

• Oxidation of intramyocellular lipids is dependent on mitochondrial function and the availability of extracellular fatty acids.

  American journal of physiology. Endocrinology and metabolism 20100701

• Glutamate-induced alterations in Ca2+ signaling are modulated by mitochondrial Ca2+ handling capacity in brain slices of R6/1 transgenic mice.

  The European journal of neuroscience 20100701

• Monitoring mitochondrial [Ca(2+)] dynamics with rhod-2, ratiometric pericam and aequorin.

  Cell calcium 20100701

• Carbonyl cyanide p-(trifluoromethoxy) phenylhydroazone induces caspase-independent apoptosis in As4.1 juxtaglomerular cells.

  Anticancer research 20100701

• Greater cytosolic and mitochondrial calcium transients in adrenal medullary slices of hypertensive, compared with normotensive rats.

  European journal of pharmacology 20100625

• Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity.

  The Journal of physiology 20100615

• Oxygen-dependence of metabolic rate in the muscles of craniates.

  Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20100601

• Mitochondrial uncoupler FCCP activates proton conductance but does not block store-operated Ca(2+) current in liver cells.

  Archives of biochemistry and biophysics 20100315

• Altered myoplasmic Ca(2+) handling in rat fast-twitch skeletal muscle fibres during disuse atrophy.

  Pflugers Archiv : European journal of physiology 20100301

• Mitochondrial Ca2+ activates a cation current in Aplysia bag cell neurons.

  Journal of neurophysiology 20100301

• Assessment of mitochondrial potential: implications for the correct monitoring of human sperm function.

  International journal of andrology 20100201

• Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis.

  The Journal of biological chemistry 20100101

• Extracellular ATP and P2Y2 receptors mediate intercellular Ca(2+) waves induced by mechanical stimulation in submandibular gland cells: Role of mitochondrial regulation of store operated Ca(2+) entry.

  Cell calcium 20100101

• Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro.

  PloS one 20100101

• Uncoupling protein-1 is not leaky.

  Biochimica et biophysica acta 20100101

• On the mechanism of chloroquine resistance in Plasmodium falciparum.

  PloS one 20100101

• Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells.

  BMC plant biology 20100101

• Examining the neglected side of calcium regulation in taste cells.

  The Journal of physiology 20091201

• Effects of carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone on the growth inhibition in human pulmonary adenocarcinoma Calu-6 cells.

  Toxicology 20091130

• The optimal dosage and window of opportunity to maintain mitochondrial homeostasis following traumatic brain injury using the uncoupler FCCP.

  Experimental neurology 20090801

• Modulation of Trypanosoma rangeli ecto-phosphatase activity by hydrogen peroxide.

  Free radical biology & medicine 20090715

• Modulation of mitochondrial K(+) permeability and reactive oxygen species production by the p13 protein of human T-cell leukemia virus type 1.

  Biochimica et biophysica acta 20090701

• Stimulation of glutamate receptors in cultured hippocampal neurons causes Ca2+-dependent mitochondrial contraction.

  Cell calcium 20090701

• Factors affecting SOCE activation in mammalian skeletal muscle fibers.

  The journal of physiological sciences : JPS 20090701

• Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila.

  PLoS pathogens 20090701

• Metabolic inhibition strongly inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes.

  Biophysical journal 20090617

• Regulation of glycolytic oscillations by mitochondrial and plasma membrane H+-ATPases.

  Biophysical journal 20090506

• Kir 2.2 inward rectifier potassium channels are inhibited by an endogenous factor in Xenopus oocytes independently from the action of a mitochondrial uncoupler.

  Journal of cellular physiology 20090401

• Role of the endoplasmic reticulum and mitochondria on quantal catecholamine release from chromaffin cells of control and hypertensive rats.

  The Journal of pharmacology and experimental therapeutics 20090401

• Uncouple my heart: the benefits of inefficiency.

  Journal of bioenergetics and biomembranes 20090401

• Features of mitochondrial energetics in living unicellular eukaryote Tetrahymena pyriformis. A model for study of mammalian intracellular adaptation.

  Biochemistry. Biokhimiia 20090401

• In vitro-matured rat oocytes have low mitochondrial deoxyribonucleic acid and adenosine triphosphate contents and have abnormal mitochondrial redistribution.

  Fertility and sterility 20090301

• Mitochondrial free [Ca2+] levels and the permeability transition.

  Cell calcium 20090301

• Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells.

  Lung cancer (Amsterdam, Netherlands) 20090201

• Biosensor plates detect mitochondrial physiological regulators and mutations in vivo.

  Analytical biochemistry 20090201

• Knockdown of JNK rescues 3T3-L1 adipocytes from insulin resistance induced by mitochondrial dysfunction.

  Biochemical and biophysical research communications 20090123

• Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies.

  Bioorganic & medicinal chemistry 20090115

• Calcium homeostasis is dysregulated in parkinsonian patients with L-DOPA-induced dyskinesias.

  Clinical neuropharmacology 20090101

• Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARgamma-independent mechanism, whereas TNFalpha-induced de-differentiation is PPARgamma dependent.

  Journal of cell science 20090101

• Distribution characteristics of telithromycin, a novel ketolide antimicrobial agent applied for treatment of respiratory infection, in lung epithelial lining fluid and alveolar macrophages.

  Drug metabolism and pharmacokinetics 20090101

• Acute inhibition of selected membrane-proximal mouse T cell receptor signaling by mitochondrial antagonists.

  PloS one 20090101

• Regulation of 5-aminolevulinic acid-mediated protoporphyrin IX accumulation in human urothelial carcinomas.

  Pathobiology : journal of immunopathology, molecular and cellular biology 20090101

• Indirubin-3'-oxime impairs mitochondrial oxidative phosphorylation and prevents mitochondrial permeability transition induction.

  Toxicology and applied pharmacology 20081201

• Detailing the role of Bax translocation, cytochrome c release, and perinuclear clustering of the mitochondria in the killing of HeLa cells by TNF.

  Journal of cellular physiology 20081101

• Mitochondria-derived reactive oxygen species mediate sympathoexcitation induced by angiotensin II in the rostral ventrolateral medulla.

  Journal of hypertension 20081101

• Mitochondrial uncouplers act synergistically with the fumigant phosphine to disrupt mitochondrial membrane potential and cause cell death.

  Toxicology 20081030

• Metabolic pathways in Anopheles stephensi mitochondria.

  The Biochemical journal 20081015

• Mitochondrial calcium buffering contributes to the maintenance of Basal calcium levels in mouse taste cells.

  Journal of neurophysiology 20081001

• Role of mitochondria in modulation of spontaneous Ca2+ waves in freshly dispersed interstitial cells of Cajal from the rabbit urethra.

  The Journal of physiology 20081001

• Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080924

• Real-time imaging of mitochondria in transgenic zebrafish expressing mitochondrially targeted GFP.

  BioTechniques 20080901

• Functional live cell imaging of the pulmonary neuroepithelial body microenvironment.

  American journal of respiratory cell and molecular biology 20080801

• Acetyl-L-Carnitine selectively prevents post-ischemic LTP via a possible action on mitochondrial energy metabolism.

  Neuropharmacology 20080801

• Glucose and glucose transporters regulate lymphatic pump activity through activation of the mitochondrial ATP-sensitive K+ channel.

  The journal of physiological sciences : JPS 20080801

• Essential role for Nix in autophagic maturation of erythroid cells.

  Nature 20080710

• Effects of anoxia and aglycemia on cytosolic calcium regulation in rat sensory neurons.

  Journal of neurophysiology 20080701

• Ca2+-induced Ca2+ release in Aplysia bag cell neurons requires interaction between mitochondrial and endoplasmic reticulum stores.

  Journal of neurophysiology 20080701

• Plant inner membrane anion channel (PIMAC) function in plant mitochondria.

  Plant & cell physiology 20080701

• Amiodarone increases the accumulation of DEA in a human alveolar epithelium-derived cell line.

  Biological & pharmaceutical bulletin 20080701

• Oxidative stress as regulatory factor for fatty-acid-induced uncoupling involving liver mitochondrial ADP/ATP and aspartate/glutamate antiporters of old rats.

  Biochemistry. Biokhimiia 20080701

• Detection of de- and hyperpolarization of mitochondria of cultured astrocytes and neurons by the cationic fluorescent dye rhodamine 123.

  Journal of neuroscience methods 20080615

• Dual effect of nitric oxide on ATP-sensitive K+ channels in rat pancreatic beta cells.

  Pflugers Archiv : European journal of physiology 20080601

• Human CD4(+) T cells maintain specific functions even under conditions of extremely restricted ATP production.

  European journal of immunology 20080601

• Different concentrations of berberine result in distinct cellular localization patterns and cell cycle effects in a melanoma cell line.

  Cancer chemotherapy and pharmacology 20080501

• Nitric oxide degradation by potato tuber mitochondria: evidence for the involvement of external NAD(P)H dehydrogenases.

  Biochimica et biophysica acta 20080501

• Inhibition of carrier-mediated uptake of epirubicin reduces cytotoxicity in primary culture of rat hepatocytes.

  Journal of applied toxicology : JAT 20080401

• Roles of mitochondria and temperature in the control of intracellular calcium in adult rat sensory neurons.

  Cell calcium 20080401

• Effect of metabolic inhibition on couplon behavior in rabbit ventricular myocytes.

  Biophysical journal 20080301

• Mitochondrial behavior during oogenesis in zebrafish: a confocal microscopy analysis.

  Development, growth & differentiation 20080301

• Shear fluid-induced Ca2+ release and the role of mitochondria in rat cardiac myocytes.

  Annals of the New York Academy of Sciences 20080301

• Potential contribution of a voltage-activated proton conductance to acid extrusion from rat hippocampal neurons.

  Neuroscience 20080219

• The highly toxic oxyanion tellurite (TeO (3) (2-) ) enters the phototrophic bacterium Rhodobacter capsulatus via an as yet uncharacterized monocarboxylate transport system.

  Archives of microbiology 20080201

• Effect of mitochondria poisoning by FCCP on Ca2+ signaling in mouse skeletal muscle fibers.

  Pflugers Archiv : European journal of physiology 20080101

• The use of CalciumOrange-5N as a specific marker of mitochondrial Ca2+ in mouse skeletal muscle fibers.

  Pflugers Archiv : European journal of physiology 20080101

• Effects of anoxia, aglycemia, and acidosis on cytosolic Mg2+, ATP, and pH in rat sensory neurons.

  American journal of physiology. Cell physiology 20080101

• [Release of glutamate from cytosol of synaptosomes under conditions of experimental hypergravity].

  Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101

• Mechanisms and methods in glucose metabolism and cell death.

  Methods in enzymology 20080101

• The role of UCP2 and ADP/ATP antiporter in superoxide radical-induced uncoupling in kidney mitochondria.

  Doklady. Biochemistry and biophysics 20080101

• Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria.

  FEBS letters 20071222

• Flux control analysis of mitochondrial oxidative phosphorylation in rat skeletal muscle: pyruvate and palmitoyl-carnitine as substrates give different control patterns.

  European journal of applied physiology 20071201

• Uncoupling is without an effect on the production of reactive oxygen species by in situ synaptic mitochondria.

  Journal of neurochemistry 20071201

• Rottlerin induces calcium influx and protein degradation in cultured lenses independent of effects on protein kinase C delta.

  Basic & clinical pharmacology & toxicology 20071201

• Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: comparison with direct effects on isolated mitochondrial fractions.

  The Journal of pharmacology and experimental therapeutics 20071101

• Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts.

  American journal of physiology. Heart and circulatory physiology 20071001

• Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells.

  Free radical biology & medicine 20070915

• On-line measurements of oscillating mitochondrial membrane potential in glucose-fermenting Saccharomyces cerevisiae.

  Yeast (Chichester, England) 20070901

• Modulation of CCK-8-evoked intracellular Ca2+ waves by hydrogen peroxide in mouse pancreatic acinar cells.

  Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901

• Membrane potential and H2O2 production in duodenal mitochondria from broiler chickens (Gallus gallus domesticus) with low and high feed efficiency.

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070801

• Saturable uptake of lipophilic amine drugs into isolated hepatocytes: mechanisms and consequences for quantitative clearance prediction.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• Glitazones induce astroglioma cell death by releasing reactive oxygen species from mitochondria: modulation of cytotoxicity by nitric oxide.

  Molecular pharmacology 20070801

• Metabolic inhibition-induced transient Ca2+ increase depends on mitochondria in a human proximal renal cell line.

  American journal of physiology. Renal physiology 20070801

• Superoxide (*O2- ) production in CA1 neurons of rat hippocampal slices exposed to graded levels of oxygen.

  Journal of neurophysiology 20070801

• The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondria.

  Cell calcium 20070701

• Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries.

  American journal of physiology. Heart and circulatory physiology 20070701

• Regulation of transient receptor potential melastatin 7 (TRPM7) currents by mitochondria.

  Molecules and cells 20070630

• 'Mild Uncoupling' does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress.

  Journal of neurochemistry 20070601

• Low mitochondrial DNA and ATP contents contribute to the absence of birefringent spindle imaged with PolScope in in vitro matured human oocytes.

  Human reproduction (Oxford, England) 20070601

• Role of Ca2+-independent phospholipase A2gamma in Ca2+-induced mitochondrial permeability transition.

  The Journal of pharmacology and experimental therapeutics 20070501

• Post-Injury Administration of Mitochondrial Uncouplers Increases Tissue Sparing and Improves Behavioral Outcome following Traumatic Brain Injury in Rodents.

  Journal of neurotrauma 20070501

• Effect of the inhibitory neurotransmitter glycine on slow destructive processes in brain cortex slices under anoxic conditions.

  Biochemistry. Biokhimiia 20070501

• ROS generation in endothelial hypoxia and reoxygenation stimulates MAP kinase signaling and kinase-dependent neutrophil recruitment.

  Free radical biology & medicine 20070415

• Topography of the active site of the Saccharomyces cerevisiae plasmalemmal dicarboxylate transporter studied using lipophilic derivatives of its substrates.

  Biochemistry. Biokhimiia 20070301

• Targeting the hypoxia inducible factor pathway with mitochondrial uncouplers.

  Molecular and cellular biochemistry 20070201

• Bidirectional Ca2+ coupling of mitochondria with the endoplasmic reticulum and regulation of multimodal Ca2+ entries in rat brown adipocytes.

  American journal of physiology. Cell physiology 20070201

• Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines.

  Biochimica et biophysica acta 20070201

• Downmodulation of mitochondrial F0F1 ATP synthase by diazoxide in cardiac myoblasts: a dual effect of the drug.

  American journal of physiology. Heart and circulatory physiology 20070201

• Moderate dependence of ROS formation on DeltaPsim in isolated brain mitochondria supported by NADH-linked substrates.

  Neurochemical research 20070101

• Anoxia-induced changes in pyridine nucleotide redox state in cortical neurons and astrocytes.

  Neurochemical research 20070101

• Inhibitory effect of t-butyl hydroperoxide on mitochondrial oxidative phosphorylation in isolated rat hepatocytes.

  Physiological research 20070101

• The KATP channel is critical for calcium sequestration into non-ER compartments in mouse pancreatic beta cells.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Local influence of mitochondrial calcium transport in retinal amacrine cells.

  Visual neuroscience 20070101

• Effect of oxidative phosphorylation uncoupler FCCP and F1F0-ATPase inhibitor oligomycin on the electromechanical activity of human myocardium.

  Advances in medical sciences 20070101

• Homocysteine-mediated activation and mitochondrial translocation of calpain regulates MMP-9 in MVEC.

  American journal of physiology. Heart and circulatory physiology 20061201

• Irgarol inhibits the synthesis of ATP in mitochondria from rat liver.

  Chemosphere 20061201

• Hydrogen peroxide: a feed-forward dilator that couples myocardial metabolism to coronary blood flow.

  Arteriosclerosis, thrombosis, and vascular biology 20061201

• Preliminary evidence on existence of transplasma membrane electron transport in Entamoeba histolytica trophozoites: a key mechanism for maintaining optimal redox balance.

  Journal of bioenergetics and biomembranes 20061201

• The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells.

  International journal of pharmaceutics 20061115

• Accumulation of lipophilic dications by mitochondria and cells.

  The Biochemical journal 20061115

• Integration of rapid cytosolic Ca2+ signals by mitochondria in cat ventricular myocytes.

  American journal of physiology. Cell physiology 20061101

• Carboxyatractyloside effects on brown-fat mitochondria imply that the adenine nucleotide translocator isoforms ANT1 and ANT2 may be responsible for basal and fatty-acid-induced uncoupling respectively.

  The Biochemical journal 20061101

• Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation.

  Cardiovascular research 20061101

• FCCP is cardioprotective at concentrations that cause mitochondrial oxidation without detectable depolarisation.

  Cardiovascular research 20061101

• Properties of yeast Saccharomyces cerevisiae plasma membrane dicarboxylate transporter.

  Biochemistry. Biokhimiia 20061001

• Differential role of Presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts.

  Journal of neuroscience research 20060901

• The spirostenol (22R, 25R)-20alpha-spirost-5-en-3beta-yl hexanoate blocks mitochondrial uptake of Abeta in neuronal cells and prevents Abeta-induced impairment of mitochondrial function.

  Steroids 20060801

• Arachidonic acid enhances intracellular [Ca2+]i increase and mitochondrial depolarization induced by glutamate in cerebellar granule cells.

  Biochemistry. Biokhimiia 20060801

• Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function.

  Journal of neurochemistry 20060701

• Characterization of ryanodine receptor-mediated calcium release in human B cells: relevance to diagnostic testing for malignant hyperthermia.

  Anesthesiology 20060601

• Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.

  The Journal of biological chemistry 20060414

• Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.

  Cell death and differentiation 20060401

• Cross-talk between the sarcoplasmic reticulum and the mitochondrial calcium handling systems may play an important role in the regulation of contraction in anococcygeus smooth muscle.

  Mitochondrion 20060401

• Spatially organised mitochondrial calcium uptake through a novel pathway in chick neurones.

  Cell calcium 20060301

• Mitochondrial Ca2+ flux is a critical determinant of the Ca2+ dependence of mast cell degranulation.

  Journal of leukocyte biology 20060301

• Glutamate stimulates oligodendrocyte progenitor migration mediated via an alphav integrin/myelin proteolipid protein complex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060301

• Histamine-mediated increases in cytosolic [Ca2+] involve different mechanisms in human pulmonary artery smooth muscle and endothelial cells.

  American journal of physiology. Cell physiology 20060201

• Calcium mobilization by nicotinic acid adenine dinucleotide phosphate (NAADP) in rat astrocytes.

  Cell calcium 20060201

• V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.

  Nature cell biology 20060201

• Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes.

  Neuroscience letters 20060130

• Aging-related changes of intracellular Ca2+ stores and contractile response of intestinal smooth muscle.

  Experimental gerontology 20060101

• Rottlerin inhibits stimulated enzymatic secretion and several intracellular signaling transduction pathways in pancreatic acinar cells by a non-PKC-delta-dependent mechanism.

  Biochimica et biophysica acta 20060101

• Mechanism of toxicity of the branched-chain fatty acid phytanic acid, a marker of Refsum disease, in astrocytes involves mitochondrial impairment.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20060101

• Thyroid hormone and thyrotropin regulate intracellular free calcium concentrations in human polymorphonuclear leukocytes: in vivo and in vitro studies.

  International journal of immunopathology and pharmacology 20060101

• Properties of the permeability transition in VDAC1(-/-) mitochondria.

  Biochimica et biophysica acta 20060101

• Hypoxic regulation of Ca2+ signalling in astrocytes and endothelial cells.

  Advances in experimental medicine and biology 20060101

• Effect of oxidative stress on dynamics of mitochondrial reticulum.

  Biochimica et biophysica acta 20060101

• [Effect of substances which change the proton-motive force on activity of methane microbe oxygenation].

  Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20060101

• Close functional coupling between Ca2+ release-activated Ca2+ channels and reactive oxygen species production in murine macrophages.

  Mediators of inflammation 20060101

• Effect of triclosan (TRN) on energy-linked functions of rat liver mitochondria.

  Toxicology letters 20051230

• Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions.

  Neurobiology of disease 20051201

• Effects of beauvericin on the metabolic state and ionic homeostasis of ventricular myocytes of the guinea pig.

  Chemical research in toxicology 20051101

• Blood pressure fall and increased relaxation of aortic smooth muscle in diabetic rats.

  Diabetes & metabolism 20051101

• Expression and modulation of an NADPH oxidase in mammalian astrocytes.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20051005

• Effect of selenium-supplement on the calcium signaling in human endothelial cells.

  Journal of cellular physiology 20051001

• An alternative Ca2+-dependent mechanism of neuroprotection by the metalloporphyrin class of superoxide dismutase mimetics.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001

• Role of NAD(P)H oxidase in the regulation of cardiac L-type Ca2+ channel function during acute hypoxia.

  Cardiovascular research 20050901

• Phenolsulfonphthalein transport by potential-sensitive urate transport system.

  European journal of pharmacology 20050822

• Gene expression changes in human small airway epithelial cells exposed to Delta9-tetrahydrocannabinol.

  Toxicology letters 20050814

• Analysis of mitochondrial membrane potential in the cells by microchip flow cytometry.

  Electrophoresis 20050801

• Mitochondrial nitric oxide mediates decreased vulnerability of hippocampal neurons from immature animals to NMDA.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713

• Inhibition of the mitochondrial ATP synthesis by polygodial, a naturally occurring dialdehyde unsaturated sesquiterpene.

  Biochemical pharmacology 20050701

• Mitochondrial Ca2+ buffering in hypoglossal motoneurons from mouse.

  Neuroscience letters 20050603

• Assessment of mitochondrial membrane potential in proximal tubules after hypoxia-reoxygenation.

  American journal of physiology. Renal physiology 20050601

• Phenylarsine oxide is able to dissipate synaptic vesicle acidic pool.

  Neurochemistry international 20050601

• Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10.

  Journal of neurochemistry 20050601

• Mitochondria are intracellular magnesium stores: investigation by simultaneous fluorescent imagings in PC12 cells.

  Biochimica et biophysica acta 20050515

• Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.

  The Journal of biological chemistry 20050513

• Differential sensitivity of Kir2 inward-rectifier potassium channels to a mitochondrial uncoupler: identification of a regulatory site.

  Molecular pharmacology 20050401

• Metabolic inhibition alters subcellular calcium release patterns in rat ventricular myocytes: implications for defective excitation-contraction coupling during cardiac ischemia and failure.

  Circulation research 20050318

• Cellular and subcellular calcium accumulation during glutamate-induced injury in cerebellar granule neurons.

  Journal of neurochemistry 20050301

• Formation of insoluble magnesium phosphates during growth of the archaea Halorubrum distributum and Halobacterium salinarium and the bacterium Brevibacterium antiquum.

  FEMS microbiology ecology 20050301

• Proton transfer through the membrane-water interfaces in uncoupled mitochondria.

  Biochemistry. Biokhimiia 20050201

• Regulation of inward rectifier K+ channels by shift of intracellular pH dependence.

  Journal of cellular physiology 20050101

• Hypoxic regulation of Ca2+ signaling in cultured rat astrocytes.

  Glia 20050101

• Glutamate-mediated influx of extracellular Ca2+ is coupled with reactive oxygen species generation in cultured hippocampal neurons but not in astrocytes.

  Journal of neuroscience research 20050101

• [A correlation between respiration and synthesis of ATP in mitochondria at different degree of uncoupling of oxidative phosphorylation].

  Biofizika 20050101

• Mitochondrial activation and the pyruvate paradox in a human cell line.

  FEBS letters 20041217

• Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20041001

• Intracellular pH and KATP channel activity in dorsal vagal neurons of juvenile rats in situ during metabolic disturbances.

  Brain research 20040813

• A novel mechanism of regulation of cardiac contractility by mitochondrial functional state.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801

• Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant.

  FEBS letters 20040730

• Induction of the mitochondrial permeability transition by the DNA alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine. Sorting cause and consequence of mitochondrial dysfunction.

  Biochimica et biophysica acta 20040723

• 'Wages of fear': transient threefold decrease in intracellular ATP level imposes apoptosis.

  Biochimica et biophysica acta 20040723

• Transmembrane reorientation of the substrate-binding site in vesicular acetylcholine transporter.

  Biochemistry 20040713

• Maternally-inherited Leigh syndrome-related mutations bolster mitochondrial-mediated apoptosis.

  Journal of neurochemistry 20040701

• Developmental up-regulation of MnSOD in rat oligodendrocytes confers protection against oxidative injury.

  The European journal of neuroscience 20040701

• Oxygen consumption in unfertilized salmonid eggs: an indicator of egg quality?

  Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040701

• Rotenone-sensitive mitochondrial potential in Phytomonas serpens: electrophoretic Ca(2+) accumulation.

  Biochimica et biophysica acta 20040607

• Partial reconstruction of in vitro gluconeogenesis arising from mitochondrial l-lactate uptake/metabolism and oxaloacetate export via novel L-lactate translocators.

  The Biochemical journal 20040515

• Functional transitions of F0F1-ATPase mediated by the inhibitory peptide IF1 in yeast coupled submitochondrial particles.

  European journal of biochemistry 20040501

• Characteristics of intermittent mitochondrial transport in guinea pig enteric nerve fibers.

  American journal of physiology. Gastrointestinal and liver physiology 20040401

• Involvement of membrane GABA transporter in alpha-latrotoxin-stimulated [3H]GABA release.

  Neurochemistry international 20040401

• The effect of mitochondrial inhibitors on membrane currents in isolated neonatal rat carotid body type I cells.

  The Journal of physiology 20040401

• Differences in toxicity of the catechol-O-methyl transferase inhibitors, tolcapone and entacapone to cultured human neuroblastoma cells.

  Neuropharmacology 20040301

• Assay of mitochondrial functions by resazurin in vitro.

  Acta pharmacologica Sinica 20040301

• Mitochondrial polarisation status and [Ca2+]i signalling in rat cerebellar granule neurones aged in vitro.

  Neurobiology of aging 20040301

• Mitochondrial calcium uptake stimulates nitric oxide production in mitochondria of bovine vascular endothelial cells.

  American journal of physiology. Cell physiology 20040201

• Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii yoelii mitochondria in situ.

  The Journal of biological chemistry 20040102

• NMDA-evoked consumption and recovery of mitochondrially targeted aequorin suggests increased Ca2+ uptake by a subset of mitochondria in hippocampal neurons.

  Brain research 20031212

• Mechanism of superoxide anion generation in intact mitochondria in the presence of lucigenin and cyanide.

  Biochemistry. Biokhimiia 20031201

• Tellurite uptake by cells of the facultative phototroph Rhodobacter capsulatus is a Delta pH-dependent process.

  FEBS letters 20031120

• Inner mitochondrial membrane potential (DeltaPsim), cytoplasmic ATP content and free Ca2+ levels in metaphase II mouse oocytes.

  Human reproduction (Oxford, England) 20031101

• Arsenate transport and reduction in the hyper-tolerant fungus Aspergillus sp. P37.

  Environmental microbiology 20031101

• Preconditioning of cortical neurons by oxygen-glucose deprivation: tolerance induction through abbreviated neurotoxic signaling.

  American journal of physiology. Cell physiology 20031001

• Both calcium and ROS as common signals mediate Na(2)SeO(3)-induced apoptosis in SW480 human colonic carcinoma cells.

  Journal of inorganic biochemistry 20031001

• Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

  Journal of neurochemistry 20030901

• Decrease of intracellular ATP content downregulated UCP2 expression in mouse hepatocytes.

  Biochemical and biophysical research communications 20030829

• Glutamate decreases mitochondrial size and movement in primary forebrain neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030827

• Mitochondrial and myoplasmic [Ca2+] in single fibres from mouse limb muscles during repeated tetanic contractions.

  The Journal of physiology 20030815

• Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.

  The Biochemical journal 20030701

• Effects of fatty acids in isolated mitochondria: implications for ischemic injury and cardioprotection.

  American journal of physiology. Heart and circulatory physiology 20030701

• Hyperforin inhibits vesicular uptake of monoamines by dissipating pH gradient across synaptic vesicle membrane.

  Life sciences 20030613

• Rapid reduction of ATP synthesis and lack of free radical formation by MPP+ in rat brain synaptosomes and mitochondria.

  Brain research 20030613

• Effects of minimally toxic levels of carbonyl cyanide P-(trifluoromethoxy) phenylhydrazone (FCCP), elucidated through differential gene expression with biochemical and morphological correlations.

  Toxicological sciences : an official journal of the Society of Toxicology 20030601

• A cuvette-based fluorometric analysis of mitochondrial membrane potential measured in cultured astrocyte monolayers.

  Journal of neuroscience methods 20030530

• Effect of transforming growth factor-beta on calcium homeostasis in prostate carcinoma cells.

  Biochemical and biophysical research communications 20030516

• Propagation of slow waves requires IP3 receptors and mitochondrial Ca2+ uptake in canine colonic muscles.

  The Journal of physiology 20030515

• Age-related changes in neuronal glucose uptake in response to glutamate and beta-amyloid.

  Journal of neuroscience research 20030515

• Regulation of the cardiac mitochondrial membrane potential by retinoids.

  The Journal of pharmacology and experimental therapeutics 20030501

• Identification of oligomerization and drug-binding domains of the membrane fusion protein EmrA.

  The Journal of biological chemistry 20030411

• A novel signalling pathway originating in mitochondria modulates rat skeletal muscle membrane excitability.

  The Journal of physiology 20030401

• Comparison of the effect of mitochondrial inhibitors on mitochondrial membrane potential in two different cell lines using flow cytometry and spectrofluorometry.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030401

• Effects of mitochondrial uncoupling on adipocyte intracellular Ca(2+) and lipid metabolism.

  The Journal of nutritional biochemistry 20030401

• Na+/Mg2+ transporter acts as a Mg2+ buffering mechanism in PC12 cells.

  Biochemical and biophysical research communications 20030328

• Mitochondria efficiently buffer subplasmalemmal Ca2+ elevation during agonist stimulation.

  The Journal of biological chemistry 20030321

• Metabolic regulation of Ca2+ release in permeabilized mammalian skeletal muscle fibres.

  The Journal of physiology 20030301

• Mechano-oxidative coupling by mitochondria induces proinflammatory responses in lung venular capillaries.

  The Journal of clinical investigation 20030301

• Potentiation of Fas-mediated apoptosis by attenuated production of mitochondria-derived reactive oxygen species.

  Cell death and differentiation 20030301

• The mitochondrial network of human neutrophils: role in chemotaxis, phagocytosis, respiratory burst activation, and commitment to apoptosis.

  Journal of immunology (Baltimore, Md. : 1950) 20030215

• Effects of hypoxia and mitochondrial inhibition on the capacitative calcium entry in rabbit pulmonary arterial smooth muscle cells.

  Life sciences 20030214

• Mitochondrial respiration and Ca2+ waves are linked during fertilization and meiosis completion.

  Development (Cambridge, England) 20030201

• Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis.

  Journal of cell science 20030201

• Platelet-activating factor and solute transport processes in the kidney.

  American journal of physiology. Renal physiology 20030201

• Delta 9-tetrahydrocannabinol disrupts mitochondrial function and cell energetics.

  American journal of physiology. Lung cellular and molecular physiology 20030201

• The production of nitric oxide in EL4 lymphoma cells overexpressing growth hormone.

  Journal of neuroimmunology 20030101

• Agonist-induced mitochondrial Ca2+ transients in smooth muscle.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030101

• Inhibitory effects of Bcl-2 on mitochondrial respiration.

  Physiological research 20030101

• Non-invasive glucose monitoring by NAD(P)H autofluorescence spectroscopy in fibroblasts and adipocytes: a model for skin glucose sensing.

  Diabetes technology & therapeutics 20030101

• [Role of the ADP/ATP and aspartate/glutamate antiporters in the uncoupling effect of fatty acids in the liver mitochondria of the frog Rana temporaria].

  Zhurnal evoliutsionnoi biokhimii i fiziologii 20030101

• Mitochondrial Ca2+ in mouse soleus single muscle fibres in response to repeated tetanic contractions.

  Advances in experimental medicine and biology 20030101

• NMDA receptor activation contributes to a portion of the decreased mitochondrial membrane potential and elevated intracellular free calcium in strain-injured neurons.

  Journal of neurotrauma 20021201

• High-throughput measurement of mitochondrial membrane potential in a neural cell line using a fluorescence plate reader.

  Biochemical and biophysical research communications 20021115

• Simultaneous determination of cyanide and carbonyls in cyanogenic plants by gas chromatography-electron capture/photoionization detection.

  The Analyst 20021101

• Lucigenin-derived chemiluminescence in intact isolated mitochondria.

  Biochemistry. Biokhimiia 20021101

• Adenoviral-induced islet cell cytotoxicity is not counteracted by Bcl-2 overexpression.

  Molecular medicine (Cambridge, Mass.) 20021101

• Facilitated diffusion of urate in avian brush-border membrane vesicles.

  American journal of physiology. Cell physiology 20021001

• Time course of action of antagonists of mitochondrial Ca uptake in intact ventricular myocytes.

  Pflugers Archiv : European journal of physiology 20021001

• Differential sensitivity of inward rectifier K+ channels to metabolic inhibitors.

  The Journal of biological chemistry 20020927

• Role of Hsp70 (DnaK-DnaJ-GrpE) and Hsp100 (ClpA and ClpB) chaperones in refolding and increased thermal stability of bacterial luciferases in Escherichia coli cells.

  Biochemistry. Biokhimiia 20020901

• Mitochondrial Ca2+ uptake regulates the excitability of myenteric neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020815

• Carotid body chemosensory excitation induced by nitric oxide: involvement of oxidative metabolism.

  Respiratory physiology & neurobiology 20020801

• Ouabain suppresses glucose-induced mitochondrial ATP production and insulin release by generating reactive oxygen species in pancreatic islets.

  Diabetes 20020801

• Coupling of calcium homeostasis to axonal sodium in axons of mouse optic nerve.

  Journal of neurophysiology 20020801

• Membrane depolarization of isolated rat liver mitochondria attenuates permeability transition pore opening and oxidant production.

  Antioxidants & redox signaling 20020801

• Development of a high throughput screening assay for mitochondrial membrane potential in living cells.

  Journal of biomolecular screening 20020801

• Intracellular distribution of the fluorescent dye nonyl acridine orange responds to the mitochondrial membrane potential: implications for assays of cardiolipin and mitochondrial mass.

  Journal of neurochemistry 20020701

• Mitochondrial sequestration and Ca(2+)-dependent release of cytosolic Zn(2+) loads in cortical neurons.

  Neurobiology of disease 20020701

• Contribution of glycolytic and mitochondrial pathways in glucose-induced changes in islet respiration and insulin secretion.

  Pflugers Archiv : European journal of physiology 20020701

• Evaluation of beta-amyloid peptide 25-35 on calcium homeostasis in cultured rat dorsal root ganglion neurons.

  Brain research 20020607

• Contribution of Ca(2+) transporters to relaxation in intact ventricular myocytes from developing rats.

  American journal of physiology. Heart and circulatory physiology 20020601

• Regulation of intracellular calcium in N1E-115 neuroblastoma cells: the role of Na(+)/Ca(2+) exchange.

  American journal of physiology. Cell physiology 20020501

• Acetylcholine and potassium elicit different patterns of exocytosis in chromaffin cells when the intracellular calcium handling is disturbed.

  Pflugers Archiv : European journal of physiology 20020501

• Inhibition of mitochondrial function affects cellular Ca2+ handling in pancreatic B-cells.

  Pflugers Archiv : European journal of physiology 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Impairment of mitochondrial metabolism differentially affects striatal neuronal subtypes.

  Neuroreport 20020416

• Glucose release from GLUT2-null hepatocytes: characterization of a major and a minor pathway.

  American journal of physiology. Endocrinology and metabolism 20020401

• Thyroxine reversibly inhibits the uncoupling action of protonophores on energy production in rat thymus lymphocytes.

  Biochemistry. Biokhimiia 20020401

• Distinct effects of different calcium-mobilizing agents on cell death in NG108-15 neuroblastoma X glioma cells.

  Molecular pharmacology 20020301

• Mitochondrial Ca(2+) buffering regulates synaptic transmission between retinal amacrine cells.

  Journal of neurophysiology 20020301

• NMDA-induced calcium loads recycle across the mitochondrial inner membrane of hippocampal neurons in culture.

  Journal of neurophysiology 20020201

• Modulation of apoptosis by mitochondrial uncouplers: apoptosis-delaying features despite intrinsic cytotoxicity.

  Biochemical pharmacology 20020201

• Mitochondria regulate Ca2+ wave initiation and inositol trisphosphate signal transduction in oligodendrocyte progenitors.

  Journal of neurochemistry 20020201

• Anacardic acid-mediated changes in membrane potential and pH gradient across liposomal membranes.

  Biochimica et biophysica acta 20020102

• FCCP depolarizes plasma membrane potential by activating proton and Na+ currents in bovine aortic endothelial cells.

  Pflugers Archiv : European journal of physiology 20020101

• Elevated intracellular zinc and altered proton homeostasis in forebrain neurons.

  Neuroscience 20020101

• Active transport of L-proline in Trypanosoma cruzi.

  The Journal of eukaryotic microbiology 20020101

• A conserved inhibitory and differential stimulatory action of nucleotides on K(IR)6.0/SUR complexes is essential for excitation-metabolism coupling by K(ATP) channels.

  The Journal of biological chemistry 20011228

• The contributions of plasma membrane Na+-Ca2+-exchange and the Ca2+-ATPase to the regulation of cytosolic calcium ([Ca2+]i) in a clonal pituitary cell line (AtT-20) of mouse corticotropes.

  Life sciences 20011228

• Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria.

  Toxicology 20011201

• Mitochondrial modulation of calcium signaling at the initiation of development.

  Cell calcium 20011201

• Amyloid beta-peptide promotes permeability transition pore in brain mitochondria.

  Bioscience reports 20011201

• Mitochondria are the main ATP source for a cytosolic pool controlling the activity of ATP-sensitive K(+) channels in mouse cardiac myocytes.

  Cardiovascular research 20011101

• Life without UCP1: mitochondrial, cellular and organismal characteristics of the UCP1-ablated mice.

  Biochemical Society transactions 20011101

• Mechanisms of the deleterious effects of tamoxifen on mitochondrial respiration rate and phosphorylation efficiency.

  Toxicology and applied pharmacology 20011101

• Confocal microscopy analysis of the activity of mitochondria contained within the 'mitochondrial cloud' during oogenesis in Xenopus laevis.

  Zygote (Cambridge, England) 20011101

• Amiloride derivatives are potent blockers of KATP channels.

  Naunyn-Schmiedeberg's archives of pharmacology 20011001

• Ethylazinphos interaction with membrane lipid organization induces increase of proton permeability and impairment of mitochondrial bioenergetic functions.

  Toxicology and applied pharmacology 20010915

• Ca(2+) and H+ homeostasis in fission yeast: a role of Ca(2+)/H+ exchange and distinct V-H+-ATPases of the secretory pathway organelles.

  FEBS letters 20010914

• Potentiation by propofol of the response of rat submandibular acinar cells to purinergic agonists.

  Cell calcium 20010901

• Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential.

  Cell death and differentiation 20010901

• Mechanisms of pH regulation in the regulated secretory pathway.

  The Journal of biological chemistry 20010831

• Ethanolamine transport in human placental brush-border membrane vesicles.

  The Journal of pharmacology and experimental therapeutics 20010801

• Development and application of a self-referencing glucose microsensor for the measurement of glucose consumption by pancreatic beta-cells.

  Analytical chemistry 20010801

• Effect of cyclosporin A and its vehicle on cardiac and skeletal muscle mitochondria: relationship to efficacy of the respiratory chain.

  British journal of pharmacology 20010701

• Carvedilol in heart mitochondria: protonophore or opener of the mitochondrial K(ATP) channels?

  Life sciences 20010601

• ATP synthesis is coupled to rat liver mitochondrial RNA synthesis.

  Molecular and cellular biochemistry 20010501

• Induction of cyclosporin A-sensitive pore in mitochondria of intact neurons during uncoupling of oxidative phosphorylation.

  Bulletin of experimental biology and medicine 20010501

• The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ.

  The Journal of biological chemistry 20010413

• Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).

  European journal of pharmacology 20010413

• Photoreducible high spin iron electron paramagnetic resonance signals in dark-adapted Photosystem II: are they oxidised non-haem iron formed from interaction of oxygen with PSII electron acceptors?

  Biochimica et biophysica acta 20010402

• Activation of K+ channels induces apoptosis in vascular smooth muscle cells.

  American journal of physiology. Cell physiology 20010401

• A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.

  Journal of neurochemistry 20010401

• Carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP) induces initiation factor 2 alpha phosphorylation and translation inhibition in PC12 cells.

  FEBS letters 20010309

• N-methyl-D-aspartate receptor-mediated mitochondrial Ca(2+) overload in acute excitotoxic motor neuron death: a mechanism distinct from chronic neurotoxicity after Ca(2+) influx.

  Journal of neuroscience research 20010301

• Calcium-magnesium interactions in pancreatic acinar cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010301

• The effects of singlet oxygen produced by photodynamic action on the mitochondrial permeability transition differ in accordance with the localization of the sensitizer.

  Archives of biochemistry and biophysics 20010215

• Nucleotide effects on liver and muscle mitochondrial non-phosphorylating respiration and membrane potential.

  Biochimica et biophysica acta 20010119

• MitoTracker labeling in primary neuronal and astrocytic cultures: influence of mitochondrial membrane potential and oxidants.

  Journal of neuroscience methods 20010115

• Cumulative and irreversible cardiac mitochondrial dysfunction induced by doxorubicin.

  Cancer research 20010115

• Increased sensitivity of mitochondrial respiration to inhibition by nitric oxide in cardiac hypertrophy.

  Journal of molecular and cellular cardiology 20010101

• Release of calcium from mitochondrial and nonmitochondrial intracellular stores in mouse pancreatic acinar cells by hydrogen peroxide.

  The Journal of membrane biology 20010101

• Regulation of cyclosporin A sensitive mitochondrial permeability transition by the redox state of pyridine nucleotides.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010101

• Targeting of reporter molecules to mitochondria to measure calcium, ATP, and pH.

  Methods in cell biology 20010101

• Gene therapy with sodium/iodide symporter in hepatocarcinoma.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20010101

• The excitatory effect of nitric oxide on carotid body chemoreception is blocked by oligomycin.

  Advances in experimental medicine and biology 20010101

• The synthesis and antibacterial activity of totarol derivatives. Part 3: Modification of ring-B.

  Bioorganic & medicinal chemistry 20000701

• Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter.

  Pharmaceutical research 20000201

• Expression cloning of a reserpine-sensitive vesicular monoamine transporter.

  Proceedings of the National Academy of Sciences of the United States of America 19921115