37418-88-5 | 3-Hydroxyphthalic anhydride

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$6.00	$4.00
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$18.00	$12.00
10g	98%	in stock	$33.00	$23.00
25g	98%	in stock	$80.00	$56.00

Description

• Catalog Number: AB50067
• Chemical Name: 3-Hydroxyphthalic anhydride
• CAS Number: 37418-88-5
• Molecular Formula: C8H4O4
• Molecular Weight: 164.1150
• MDL Number: MFCD00011557
• SMILES: O=C1OC(=O)c2c1c(O)ccc2
• NSC Number: 80858

Computed Properties

• Complexity: 235
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.5

Upstream Synthesis Route

4-Hydroxy-2-benzofuran-1,3-dione, also known as quinizarin, is a versatile compound widely used in chemical synthesis. In organic chemistry, quinizarin serves as a valuable building block for the synthesis of various complex molecules due to its unique reactivity and functional groups. One key application of quinizarin is its use as a precursor for the synthesis of dyes and pigments. By undergoing various chemical reactions, quinizarin can be transformed into azo dyes, anthraquinone dyes, and other colorants with diverse applications in industries such as textiles, cosmetics, and printing. Additionally, quinizarin is utilized in the preparation of pharmaceutical intermediates, agrochemicals, and specialty chemicals. Its ability to participate in a range of synthetic transformations makes quinizarin an essential component in the toolbox of synthetic chemists for the creation of new compounds with tailored properties.

Literature

• Design and synthesis of marine fungal phthalide derivatives as PPAR-γ agonists.

  Bioorganic & medicinal chemistry 20120815

• [Antiviral activity of 3-hydroxyphthalic anhydride-modified ovalbumin against herpes simplex virus 2 in vitro].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110601

• Combinations of 3-hydroxyphthalic anhydride-modified ovalbumin with antiretroviral drug-based microbicide candidates display synergistic and complementary effects against HIV-1 infection.

  Journal of acquired immune deficiency syndromes (1999) 20110415

• Maleic anhydride-modified chicken ovalbumin as an effective and inexpensive anti-HIV microbicide candidate for prevention of HIV sexual transmission.

  Retrovirology 20100101

• The antiviral activity of naturally occurring proteins and their peptide fragments after chemical modification.

  Antiviral research 20030601

• 7-Hydroxyphthalide: a new natural salicylaldehyde analog from Oulenzia sp. (Astigmata: Winterschmitiidae).

  Bioscience, biotechnology, and biochemistry 20010401

• Synthesis of corollosporine, an antibacterial metabolite of the marine fungus Corollospora maritima.

  Bioscience, biotechnology, and biochemistry 20010101