3775-60-8 | 1,3,4-Oxadiazol-2-amine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$57.00	$40.00
5g	95%	in stock	$241.00	$169.00
10g	95%	in stock	$460.00	$322.00
25g	95%	in stock	$1,035.00	$724.00

Description

• Catalog Number: AF84061
• Chemical Name: 1,3,4-Oxadiazol-2-amine
• CAS Number: 3775-60-8
• Molecular Formula: C2H3N3O
• Molecular Weight: 85.0647
• MDL Number: MFCD17677516
• SMILES: Nc1nnco1
• NSC Number: 45356

Computed Properties

• Complexity: 48.1
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: -1.4

Literature

• Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.

  Bioorganic & medicinal chemistry letters 20120515

• The discovery of 2-fluoro-N-(3-fluoro-4-(5-((4-morpholinobutyl)amino)-1,3,4-oxadiazol-2-yl)phenyl)benzamide, a full agonist of the alpha-7 nicotinic acetylcholine receptor showing efficacy in the novel object recognition model of cognition enhancement.

  Bioorganic & medicinal chemistry letters 20120515

• Synthesis and tuberculostatic activity of some (4-phenylpiperazin-1-ylmethyl)-1,3,4-oxadiazole and (4-phenylpiperazin-1-ylmethyl)-1,2,4-triazole derivatives.

  Acta poloniae pharmaceutica 20040101

• Total synthesis of anhydrolycorinone utilizing sequential intramolecular Diels-Alder reactions of a 1,3,4-oxadiazole.

  The Journal of organic chemistry 20021018