3900-89-8 | 2-Chlorophenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$6.00	$4.00
5g	97%	in stock	$7.00	$5.00
10g	97%	in stock	$10.00	$7.00
25g	97%	in stock	$22.00	$16.00
100g	97%	in stock	$69.00	$49.00

Description

• Catalog Number: AB44000
• Chemical Name: 2-Chlorophenylboronic acid
• CAS Number: 3900-89-8
• Molecular Formula: C6H6BClO2
• Molecular Weight: 156.3746
• MDL Number: MFCD00674012
• SMILES: OB(c1ccccc1Cl)O

Computed Properties

• Complexity: 110
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-Chlorophenylboronic Acid is a versatile chemical compound that finds extensive application in chemical synthesis. Thanks to its unique molecular structure, this compound plays a crucial role in organic chemistry reactions. One primary application of 2-Chlorophenylboronic Acid is as a key building block in Suzuki coupling reactions. This classic cross-coupling reaction involves the coupling of an organoboron compound (such as 2-Chlorophenylboronic Acid) with an organic halide in the presence of a palladium catalyst.The ability of 2-Chlorophenylboronic Acid to undergo Suzuki coupling reactions makes it a valuable tool in the construction of carbon-carbon bonds. This process is essential in the synthesis of a wide range of biologically active compounds, pharmaceuticals, agrochemicals, and materials. By participating in these coupling reactions, 2-Chlorophenylboronic Acid enables chemists to efficiently create complex molecular structures with high precision and control.Additionally, 2-Chlorophenylboronic Acid can serve as a key intermediate in the synthesis of various functionalized organic molecules. Its boronic acid functionality allows for further derivatization through various transformations, expanding its utility in organic synthesis even further. Overall, the versatility and reactivity of 2-Chlorophenylboronic Acid make it an indispensable reagent in modern chemical synthesis techniques.

Literature

• Metal-free carbon-carbon bond-forming reductive coupling between boronic acids and tosylhydrazones.

  Nature chemistry 20090901