391209-55-5 | 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)benzamide

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	1 week	$176.00	$124.00
250mg	95%	1 week	$263.00	$184.00

Description

• Catalog Number: AX62290
• Chemical Name: 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)benzamide
• CAS Number: 391209-55-5
• Molecular Formula: C15H12F3IN2O3
• Molecular Weight: 452.1671
• MDL Number: MFCD32204456
• SMILES: OCCONC(=O)c1ccc(c(c1Nc1ccc(cc1F)I)F)F

Computed Properties

• Complexity: 421
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 6
• XLogP3: 3.6

Literature

• The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

  Bioorganic & medicinal chemistry letters 20081215

• 4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase.

  Journal of medicinal chemistry 20071018