392-83-6 | 2-Bromobenzotrifluoride

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$8.00	$5.00
25g	98%	in stock	$12.00	$8.00
100g	98%	in stock	$38.00	$26.00
250g	98%	in stock	$78.00	$54.00
500g	98%	in stock	$99.00	$69.00

Description

• Catalog Number: AB61497
• Chemical Name: 2-Bromobenzotrifluoride
• CAS Number: 392-83-6
• Molecular Formula: C7H4BrF3
• Molecular Weight: 225.0059
• MDL Number: MFCD00000373
• SMILES: Brc1ccccc1C(F)(F)F

Computed Properties

• Complexity: 132
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• XLogP3: 3.6

Upstream Synthesis Route

2-Bromobenzotrifluoride is a versatile compound commonly used in chemical synthesis as a key building block for various reactions. Its unique structure, consisting of a benzene ring with two substituents - a bromine atom and three fluorine atoms, allows it to participate in a wide range of transformations to yield diverse products.One of the primary applications of 2-Bromobenzotrifluoride is as a precursor for the synthesis of pharmaceuticals and agrochemicals. Its reactivity enables the introduction of the bromine atom or the trifluoromethyl group into target molecules, imparting desired properties or functionalities. Additionally, 2-Bromobenzotrifluoride can serve as a starting material for the construction of complex organic molecules through coupling reactions, such as Suzuki-Miyaura cross-coupling, Heck reaction, or nucleophilic aromatic substitution.Furthermore, 2-Bromobenzotrifluoride is utilized in the preparation of specialty chemicals, including dyes, polymers, and materials with specific electronic or structural properties. Its fluorinated nature enhances the stability and lipophilicity of the resulting compounds, making it valuable in the design of advanced materials for various industrial applications.Overall, 2-Bromobenzotrifluoride plays a crucial role in modern chemical synthesis by enabling the efficient and selective modification of organic molecules, leading to the development of novel compounds with diverse functionalities and applications.

Literature

• Bromine as the ortho-directing group in the aromatic metalation/silylation of substituted bromobenzenes.

  The Journal of organic chemistry 20031128