39217-38-4 | (S)-2-Amino-3-chloropropanoic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$18.00	$12.00
1g	95%	in stock	$24.00	$17.00
5g	95%	in stock	$116.00	$82.00
10g	95%	in stock	$201.00	$141.00
25g	95%	in stock	$448.00	$314.00

Description

• Catalog Number: AF68741
• Chemical Name: (S)-2-Amino-3-chloropropanoic acid
• CAS Number: 39217-38-4
• Molecular Formula: C3H6ClNO2
• Molecular Weight: 123.5382
• MDL Number: MFCD01632068
• SMILES: N[C@@H](C(=O)O)CCl

Computed Properties

• Complexity: 75.3
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -2.8

Literature

• Structural and mutational studies on substrate specificity and catalysis of Salmonella typhimurium D-cysteine desulfhydrase.

  PloS one 20120101

• Entamoeba invadens: sphingolipids metabolic regulation is the main component of a PKC signaling pathway in controlling cell growth and proliferation.

  Experimental parasitology 20090601

• N-chloroamino acids cause oxidative protein modifications in the erythrocyte membrane.

  Mechanisms of ageing and development 20081001

• Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis.

  Biochimica et biophysica acta 20080901

• Stereochemistry of reactions of the inhibitor/substrates L- and D-beta-chloroalanine with beta-mercaptoethanol catalysed by L-aspartate aminotransferase and D-amino acid aminotransferase respectively.

  Organic & biomolecular chemistry 20050921

• Inositol phosphoceramide synthase is a regulator of intracellular levels of diacylglycerol and ceramide during the G1 to S transition in Saccharomyces cerevisiae.

  The Biochemical journal 20050515

• Structural analysis of Pseudomonas 1-aminocyclopropane-1-carboxylate deaminase complexes: insight into the mechanism of a unique pyridoxal-5'-phosphate dependent cyclopropane ring-opening reaction.

  Biochemistry 20041026

• Skin lipid synthesis inhibition: a possible means for enhancing percutaneous delivery of levodopa.

  Current drug delivery 20041001

• Inhibition of skin sphingosine synthesis: enhanced percutaneous permeation of 5-fluorouracil.

  Die Pharmazie 20040301

• Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.

  Biochemistry 20040203

• NMR assignment of protein side chains using residue-correlated labeling and NOE spectra.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20031201

• L-alanine-glyoxylate aminotransferase II of rat kidney and liver mitochondria possesses cysteine S-conjugate beta-lyase activity: a contributing factor to the nephrotoxicity/hepatotoxicity of halogenated alkenes?

  The Biochemical journal 20031115

• Synthesis of 4-hydroxysphinganine and characterization of sphinganine hydroxylase activity in corn.

  Archives of biochemistry and biophysics 20030715

• Human mitochondrial and cytosolic branched-chain aminotransferases are cysteine S-conjugate beta-lyases, but turnover leads to inactivation.

  Biochemical pharmacology 20030115

• Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions.

  The Biochemical journal 20021115

• 3-Chloro-DL-alanine resistance by L-methionine-alpha-deamino-gamma-mercaptomethane-lyase activity.

  FEBS letters 20020717

• Role of sphingosine synthesis inhibition in transcutaneous delivery of levodopa.

  International journal of pharmaceutics 20020515

• Enzymatic assay of gamma-cystathionase activity using pyruvate oxidase-peroxidase sequential reaction.

  Journal of biochemical and biophysical methods 20020418

• Characterization of an alanine racemase gene from Lactobacillus reuteri.

  Current microbiology 20020401

• De novo synthesis and recycling pathways of sphingomyelin in rat Sertoli cells.

  Biochemical and biophysical research communications 20010309

• Synergic activity of D-cycloserine and beta-chloro-D-alanine against Mycobacterium tuberculosis.

  The Journal of antimicrobial chemotherapy 20010201