393568-74-6 | boc-d-his(trt)-oh

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$7.00	$5.00
1g	98%	in stock	$11.00	$8.00
5g	98%	in stock	$39.00	$28.00
10g	98%	in stock	$66.00	$46.00
25g	98%	in stock	$163.00	$114.00
100g	98%	in stock	$538.00	$376.00

Description

• Catalog Number: AI49655
• Chemical Name: boc-d-his(trt)-oh
• CAS Number: 393568-74-6
• Molecular Formula: C30H31N3O4
• Molecular Weight: 497.5848
• MDL Number: MFCD08274494
• SMILES: OC(=O)[C@@H](Cc1ncn(c1)C(c1ccccc1)(c1ccccc1)c1ccccc1)NC(=O)OC(C)(C)C

Computed Properties

• Complexity: 703
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 37
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 10
• XLogP3: 5.4

Upstream Synthesis Route

N-[(1,1-Dimethylethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine, commonly referred to as $name$, is a crucial compound in the realm of chemical synthesis. This compound serves as an essential building block in peptide chemistry, specifically in the protection and deprotection of amino acids during peptide synthesis.During peptide synthesis, certain amino acids need to be protected to prevent unwanted reactions from occurring at specific sites. $name$ plays a vital role in this process by acting as a protecting group for the histidine amino acid. The N-[(1,1-Dimethylethoxy)carbonyl] moiety shields the histidine residue, allowing selective reactions to take place at other sites without interfering with the histidine.Moreover, the triphenylmethyl (Trt) group in $name$ provides additional protection for the D-histidine amino acid, ensuring the synthesis proceeds efficiently and without side reactions. Through strategic deprotection steps, the desired peptide sequence can be obtained, with the histidine residue remaining intact and unaltered.In summary, the strategic application of N-[(1,1-Dimethylethoxy)carbonyl]-1-(triphenylmethyl)-D-histidine in chemical synthesis allows for the precise and controlled synthesis of complex peptides, making it an indispensable tool for peptide chemists and researchers in the field.