394-68-3 | 8-Fluoroquinoline

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$6.00	$5.00
5g	95%	in stock	$24.00	$17.00
25g	95%	in stock	$63.00	$45.00
100g	95%	in stock	$212.00	$149.00

Description

• Catalog Number: AB70237
• Chemical Name: 8-Fluoroquinoline
• CAS Number: 394-68-3
• Molecular Formula: C9H6FN
• Molecular Weight: 147.14904320000002
• MDL Number: MFCD01685514
• SMILES: Fc1cccc2c1nccc2
• NSC Number: 51786

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 2.2

Upstream Synthesis Route

8-Fluoroquinoline, a derivative of quinoline, finds widespread applications in chemical synthesis as a versatile building block. Its fluorine substituent imparts unique chemical properties that make it a valuable reagent in various synthetic pathways. In organic chemistry, 8-Fluoroquinoline serves as a key intermediate for the synthesis of pharmaceutical compounds, agrochemicals, and materials used in the electronics industry. Its ability to undergo diverse chemical transformations, including substitution, oxidation, and reduction reactions, allows for the efficient construction of complex molecular structures. Additionally, the presence of the fluorine atom can enhance the biological activity of the synthesized molecules, making 8-Fluoroquinoline an essential component in drug discovery and development. Furthermore, its compatibility with a wide range of functional groups and reaction conditions makes it a valuable tool for synthetic chemists aiming to access novel compounds with tailored properties.

Literature

• Diethyl 2-{[2-(trifluoro-meth-yl)anil-ino]methyl-idene}propane-dioate.

  Acta crystallographica. Section E, Structure reports online 20120201