39512-49-7 | 4-(4-Chlorophenyl)-4-hydroxypiperidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$16.00	$11.00
1g	97%	in stock	$23.00	$16.00
5g	97%	in stock	$49.00	$34.00
10g	97%	in stock	$72.00	$50.00
25g	97%	in stock	$148.00	$104.00
100g	97%	in stock	$541.00	$379.00

Description

• Catalog Number: AB65802
• Chemical Name: 4-(4-Chlorophenyl)-4-hydroxypiperidine
• CAS Number: 39512-49-7
• Molecular Formula: C11H14ClNO
• Molecular Weight: 211.688
• MDL Number: MFCD00006001
• SMILES: OC1(CCNCC1)c1ccc(cc1)Cl
• NSC Number: 89568

Computed Properties

• Complexity: 184
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.6

Literature

• 4-[Bis(4-fluorophenyl)methyl]piperazin-1-ium 2-(2-phenylethyl)benzoate.

  Acta crystallographica. Section E, Structure reports online 20111001

• 4-(4-Chloro-phen-yl)-4-hy-droxy-piperidinium 2-(2-phenyl-eth-yl)benzoate.

  Acta crystallographica. Section E, Structure reports online 20110701

• 4-(4-Chloro-phen-yl)-4-hy-droxy-piperidinium benzoate.

  Acta crystallographica. Section E, Structure reports online 20110601

• 4-(4-Chloro-phen-yl)-4-hy-droxy-piperidinium maleate maleic acid solvate.

  Acta crystallographica. Section E, Structure reports online 20100801

• Bis[4-(4-chloro-phen-yl)-4-hydroxy-piperidinium] dipicrate dimethyl sulfoxide solvate.

  Acta crystallographica. Section E, Structure reports online 20100501

• 4-(4-Chloro-phen-yl)piperidin-4-ol.

  Acta crystallographica. Section E, Structure reports online 20100301

• [Chemical toxicological analysis of haloperidol metabolite 4-(4-chlorophenyl)-4-hydroxypipiridine in urine by high-performance liquid chromatography].

  Sudebno-meditsinskaia ekspertiza 20090101

• Sensitive determination of 4-(4-bromophenyl)-4-hydroxypiperidine, a metabolite of bromperidol, in rat plasma by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.

  Biological & pharmaceutical bulletin 20061201

• Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acid.

  Journal of neurochemistry 20061001

• Sensitive determination of 4-(4-chlorophenyl)-4-hydroxypiperidine, a metabolite of haloperidol, in a rat biological sample by HPLC with fluorescence detection after pre-column derivatization using 4-fluoro-7-nitro-2,1,3-benzoxadiazole.

  Biomedical chromatography : BMC 20060901

• Simultaneous analysis of haloperidol, its three metabolites and two other butyrophenone-type neuroleptics by high performance liquid chromatography with dual ultraviolet detection.

  Biomedical chromatography : BMC 20060201

• Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601

• Synthesis and pharmacological activity of 4-(4'-(chlorophenyl)-4-hydroxypiperidine) derivatives.

  Chemical & pharmaceutical bulletin 20050101

• Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101

• Liquid chromatographic-mass spectrometric determination of haloperidol and its metabolites in human plasma and urine.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020825

• Comparison of SSI with APCI as an interface of HPLC-mass spectrometry for analysis of a drug and its metabolites.

  Journal of the American Society for Mass Spectrometry 20020301

• In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20011201