39562-70-4 | Nitrendipine

Packsize	Purity	Availability	Price	Discounted Price
10mg	98%	in stock	$6.00	$4.00
50mg	98%	in stock	$7.00	$5.00
250mg	98%	in stock	$12.00	$9.00
1g	98%	in stock	$28.00	$19.00
5g	98%	in stock	$85.00	$60.00
10g	≥95%	in stock	$143.00	$100.00
25g	≥95%	in stock	$272.00	$190.00
100g	98%	in stock	$1,045.00	$732.00

Description

• Catalog Number: AB77529
• Chemical Name: Nitrendipine
• CAS Number: 39562-70-4
• Molecular Formula: C18H20N2O6
• Molecular Weight: 360.3612
• MDL Number: MFCD00082255
• SMILES: CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1)[N+](=O)[O-])C(=O)OC)C
• NSC Number: 758466

Computed Properties

• Complexity: 661
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6
• Undefined Atom Stereocenter Count: 1
• XLogP3: 2.9

Literature

• Deoxynivalenol (Vomitoxin)-Induced Cholecystokinin and Glucagon-Like Peptide-1 Release in the STC-1 Enteroendocrine Cell Model Is Mediated by Calcium-Sensing Receptor and Transient Receptor Potential Ankyrin-1 Channel.

  Toxicological sciences : an official journal of the Society of Toxicology 20150601

• Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor.

  Scientific reports 20140101

• Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

  Toxicological sciences : an official journal of the Society of Toxicology 20131201

• FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

  Chemico-biological interactions 20130905

• Anti-arrhythmic and hemodynamic effects of oxy nifedipine, oxy nimodipine, oxy nitrendipine and oxy nisoldipine.

  Pharmacological research 20121001

• Involvement of basal and calcium-activated protein kinase C in neurotransmitter secretion in mouse motor synapses.

  Bulletin of experimental biology and medicine 20121001

• A novel image analysis methodology for online monitoring of nucleation and crystal growth during solid state phase transformations.

  International journal of pharmaceutics 20120820

• Solvent-mediated amorphous-to-crystalline transformation of nitrendipine in amorphous particle suspensions containing polymers.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815

• Effect of pomegranate juice on intestinal transport and pharmacokinetics of nitrendipine in rats.

  Phytotherapy research : PTR 20120801

• Facilitation of neurotransmitter release in mouse motor synapses in different modes of protein kinase C activation.

  Bulletin of experimental biology and medicine 20120801

• The development of a novel dry powder inhaler.

  International journal of pharmaceutics 20120715

• A novel surface modified nitrendipine nanocrystals with enhancement of bioavailability and stability.

  International journal of pharmaceutics 20120701

• Effect of pomegranate juice on the pharmacokinetics of nitrendipine in rabbits.

  European journal of drug metabolism and pharmacokinetics 20120601

• Capture hydrolysis signals in the microsomal stability assay: molecular mechanisms of the alkyl ester drug and prodrug metabolism.

  Bioorganic & medicinal chemistry letters 20120115

• PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans.

  Nature genetics 20120115

• Polymer-mediated anti-solvent crystallization of nitrendipine: monodispersed spherical crystals and growth mechanism.

  Pharmaceutical research 20120101

• Development of a LC-ESI-MS3 method for determination of nitrendipine in human plasma.

  Journal of pharmaceutical and biomedical analysis 20111215

• Nitrendipine nanocrystals: its preparation, characterization, and in vitro-in vivo evaluation.

  AAPS PharmSciTech 20111201

• Simultaneous determination of nitrendipine and hydrochlorothiazide in spontaneously hypertensive rat plasma using HPLC with on-line solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115

• A potential calcium antagonist and its antihypertensive effects.

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• Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.

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• Influence of dihydropyridine calcium antagonist nitrendipine on benzo(a)pyrene-induced oxidative stress.

  Archives of pharmacal research 20110701

• Differences in crystallization rate of nitrendipine enantiomers in amorphous solid dispersions with HPMC and HPMCP.

  International journal of pharmaceutics 20110404

• Preparation and characterization of nitrendipine solid lipid nanoparticles.

  Die Pharmazie 20110301

• Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier.

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• Ultra-performance liquid chromatography-tandem mass spectrometry method for the determination of nitrendipine in dog plasma and its application to a pharmacokinetic study of a solid self-emulsifying pellet formulation.

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• Redox modulation of diaphragm contractility: Interaction between DHPR and RyR channels.

  Free radical biology & medicine 20101215

• Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

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• Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study.

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• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

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• Inhibition of contractions of nerve processes in calcium-free medium.

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• Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

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• Preparation of stable nitrendipine nanosuspensions using the precipitation-ultrasonication method for enhancement of dissolution and oral bioavailability.

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• Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery.

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• LTD and LTP at the developing retinogeniculate synapse.

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• Differential roles of dihydropyridine calcium antagonist nifedipine, nitrendipine and amlodipine on gentamicin-induced renal tubular toxicity in rats.

  European journal of pharmacology 20091012

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  Journal of biomedical nanotechnology 20090201

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• Post-hypoxic changes in rat cortical neuron GABA A receptor function require L-type voltage-gated calcium channel activation.

  Neuropharmacology 20090101

• Effectiveness and tolerability of fixed-dose combination enalapril plus nitrendipine in hypertensive patients: results of the 3-month observational, post-marketing, multicentre, prospective CENIT study.

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• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

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• The effect of penetration enhancers on permeation kinetics of nitrendipine in two different skin models.

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• Application of a self-modeling curve resolution method for studying the photodegradation kinetics of nitrendipine and felodipine.

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• Alpha1A- and alpha1D-adrenoceptors are the major functional subtypes of renal alpha1-adrenoceptors in streptozotocin-induced diabetic and normal Sprague-Dawley rats.

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• Quantitative determination of nitrendipine in human plasma using high-performance liquid chromatography-mass spectrometry.

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  Drug metabolism and drug interactions 20080101

• Systolic blood pressure reduction with olmesartan medoxomil versus nitrendipine in elderly patients with isolated systolic hypertension.

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• Improvement of the dissolution rate of nitrendipine using a new pulse combustion drying method.

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• Effect of chronic hypoxia on voltage-independent calcium influx activated by 5-HT in rat intrapulmonary arteries.

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• Development and validation of a reversed-phase HPLC method for determination of nitrendipine in rat plasma: application to pharmacokinetic studies.

  Biomedical chromatography : BMC 20070401

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• Adjunctive treatment with moxonidine versus nitrendipine for hypertensive patients with advanced renal failure: a cost-effectiveness analysis.

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  Chemical & pharmaceutical bulletin 20060101

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  Archives des maladies du coeur et des vaisseaux 20030101

• Effect of combination therapy with a calcium channel blocker and an angiotensin-converting enzyme inhibitor on renal hypertrophy and urinary albumin excretion in diabetic rats.

  Experimental diabesity research 20030101

• Mechanism of nicotine-evoked release of 3H-noradrenaline in human cerebral cortex slices.

  British journal of pharmacology 20021201

• Importance of blood pressure variability in organ protection in spontaneously hypertensive rats treated with combination of nitrendipine and atenolol.

  Acta pharmacologica Sinica 20021201

• The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study.

  Archives of internal medicine 20021014

• Drotaverine interacts with the L-type Ca(2+) channel in pregnant rat uterine membranes.

  European journal of pharmacology 20020802

• Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020801

• L-type calcium channel-mediated plateau potentials in barrelette cells during structural plasticity.

  Journal of neurophysiology 20020801

• Inhibitors of phosphatidylinositol 3-kinase amplify insulin release from islets of lean but not obese mice.

  The Journal of endocrinology 20020801

• Nitrendipine blocks the nociceptive effects of chronically administered ethanol.

  Alcoholism, clinical and experimental research 20020801

• Effect of amyotrophic lateral sclerosis serum on calcium channels related to spontaneous acetylcholine release.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20020701

• Mechanism of angiotensin II-induced phospholipase D activation in bovine adrenal glomerulosa cells.

  Molecular and cellular endocrinology 20020628

• Hydrolytic degradation of nitrendipine and nisoldipine.

  Journal of pharmaceutical and biomedical analysis 20020601

• Microemulsion formulation for enhanced absorption of poorly soluble drugs. II. In vivo study.

  Journal of controlled release : official journal of the Controlled Release Society 20020517

• Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the betaHC9 cell.

  American journal of physiology. Endocrinology and metabolism 20020501

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Therapeutic effects of DCDDP, a calcium channel blocker, on chronic pulmonary hypertension in rat.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020301

• Synaptic mechanisms regulating the activation of a Ca(2+)-mediated plateau potential in developing relay cells of the LGN.

  Journal of neurophysiology 20020301

• Paradoxical release of nitric oxide by an L-type calcium channel antagonist, the R+ enantiomer of amlodipine.

  Journal of cardiovascular pharmacology 20020201

• Enalapril/nitrendipine. ENEAS, nitrendipine/enalapril.

  Drugs in R&D 20020101

• Synaptic plasticity in the trigeminal principal nucleus during the period of barrelette formation and consolidation.

  Brain research. Developmental brain research 20011214

• [Innovation, step innovation, Me too. Are calcium antagonists interchangeable?].

  MMW Fortschritte der Medizin 20011213

• Nitrendipine and enalapril combination therapy in mild to moderate hypertension: assessment of dose-response relationship by a clinical trial of factorial design.

  Journal of cardiovascular pharmacology 20011201

• Effect of bile acids on absorption of nitrendipine in healthy subjects.

  British journal of clinical pharmacology 20011201

• Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry.

  Biomedical chromatography : BMC 20011201

• Dihydropyridine calcium-channel blockers for antihypertensive treatment in older patients--evidence from the Systolic Hypertension in Europe Trial.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20011201

• The use of calcium blockers to study biochemical behaviour of Saccharomyces cerevisiae cells.

  Molecular and cellular biochemistry 20011201

• Involvement of calcium, inositol-1,4,5 trisphosphate and diacylglycerol in the prothoracicotropic hormone-stimulated ecdysteroid synthesis and secretion in the prothoracic glands of Bombyx mori.

  Zoological science 20011201

• Bending the MDCK cell primary cilium increases intracellular calcium.

  The Journal of membrane biology 20011101

• Applications of liquid chromatography-tandem mass spectrometry in drug and biomedical analyses.

  Clinica chimica acta; international journal of clinical chemistry 20011101

• Risk and benefit of treatment of isolated systolic hypertension in the elderly: evidence from the Systolic Hypertension in Europe Trial.

  Current opinion in cardiology 20011101

• Independent modulation of L-type Ca2+ channel in guinea pig ventricular cells by nitrendipine and isoproterenol.

  Japanese heart journal 20011101

• Do arterial effects of antihypertensive drugs depend on subject's serum cholesterol?

  Journal of cardiovascular pharmacology 20011001

• A double-blind trial of perindopril and nitrendipine in incipient diabetic nephropathy.

  Diabetes, nutrition & metabolism 20011001

• Parathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3).

  Bone 20010901

• Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20010815

• Calcium channels in Xenopus spinal neurons differ in somas and presynaptic terminals.

  Journal of neurophysiology 20010701

• Effect of quinapril versus nitrendipine on endothelial dysfunction in patients with systemic hypertension.

  The American journal of cardiology 20010615

• Effect of angiotensin II on calcium reabsorption by the luminal membranes of the nephron.

  American journal of physiology. Endocrinology and metabolism 20010601

• Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.

  The European journal of neuroscience 20010601

• [Hypertensive crisis, hypertensive emergency. Nitrate spray and ambulance--this can also be wrong].

  MMW Fortschritte der Medizin 20010517

• Mechanism of action of the calcium-sensing receptor in human antral gastrin cells.

  Gastroenterology 20010401

• Prognostic significance of serum creatinine and uric acid in older Chinese patients with isolated systolic hypertension.

  Hypertension (Dallas, Tex. : 1979) 20010401

• Effects of calcium channel blockers on pentylenetetrazol drug discrimination in rats.

  Alcohol (Fayetteville, N.Y.) 20010401

• The relevance of nitrendipine erythrocyte partitioning for the variability of its bioavailability parameters.

  International journal of pharmaceutics 20010314

• Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis.

  Journal of pharmaceutical and biomedical analysis 20010301

• Characterization of secretory and morphologic properties of primary cultured endocrine cells from porcine pancreata.

  Pancreas 20010301

• Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.

  Journal of hypertension 20010301

• Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.

  Pflugers Archiv : European journal of physiology 20010301

• [Effect of combination of ligustrazine and nitrendipine on hemodynamics in patients with chronic obstructive pulmonary disease].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010301

• Oxidative degradation study of nitrendipine using stability indicating, HPLC, HPTLC and spectrophotometric method.

  Journal of pharmaceutical and biomedical analysis 20010201

• Vatanidipine hydrochloride: a new long-lasting antihypertensive agent.

  Expert opinion on investigational drugs 20010101

• Calcium channels coupled to neurotransmitter release at dually innervated neuromuscular junctions in the newborn rat.

  Neuroscience 20010101

• The influence of chloroethylclonidine-induced contraction in isolated arteries of Wistar Kyoto rats: alpha1D- and alpha1A-adrenoceptors, protein kinase C, and calcium influx.

  Archives of medical research 20010101

• Computer-aided measurement of cell shortening and calcium transients in adult cardiac myocytes.

  Biotechnology progress 20010101

• [Therapeutic mechanism of combination therapy of ligustrazine and nitrendipine in treating patients with chronic obstructive pulmonary disease].

  Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20010101

• Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant.

  Proceedings of the National Academy of Sciences of the United States of America 20000705

• Haloperidol-induced catalepsy is influenced by calcium channel antagonists.

  Acta poloniae pharmaceutica 20000101

• Effects of the calcium antagonists verapamil and nitrendipine on carbamazepine withdrawal.

  Methods and findings in experimental and clinical pharmacology 19991201

• Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel.

  The American journal of physiology 19980901

• The novel insulinotropic mechanism of pimobendan: direct enhancement of the exocytotic process of insulin secretory granules by increased Ca2+ sensitivity in beta-cells.

  Endocrinology 19980301

• Evaluation of the efficacy and tolerability of nitrendipine in reducing both pressure and left ventricular mass in hypertensive type 2 diabetic patients.

  Diabetes care 19970801

• L-type calcium channels regulate gastrin release from human antral G cells.

  The American journal of physiology 19970801

• Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals.

  Hypertension (Dallas, Tex. : 1979) 19961201

• Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.

  Journal of medicinal chemistry 19960719

• Nitrendipine and enalapril improve albuminuria and glomerular filtration rate in non-insulin dependent diabetes.

  Kidney international. Supplement 19960601

• Dose effect of nitrendipine on urinary enzymes and microproteins following non-ionic radiocontrast administration.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19960301

• Antihypertensive effects of trandolapril and nitrendipine in the elderly: a controlled trial with special emphasis on time effect profiles.

  Journal of human hypertension 19960101

• Differences between haloperidol- and pimozide-induced withdrawal syndrome: a role for Ca2+ channels.

  European journal of pharmacology 19951229

• Effect of indomethacin on blood pressure control during treatment with nitrendipine.

  Blood pressure 19950901

• Delayed development of hypertension after short-term nitrendipine treatment.

  Hypertension (Dallas, Tex. : 1979) 19940701

• Doxazosin versus nitrendipine: a double-blind comparative study in patients adhering to a sodium-restricted diet.

  Cardiovascular drugs and therapy 19940601

• Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules.

  Intensive care medicine 19940101

• Combination treatment of enalapril with nitrendipine in rats with renovascular hypertension.

  Hypertension (Dallas, Tex. : 1979) 19940101

• Nocturnal hypotension and ACE inhibitors.

  Journal of human hypertension 19930601

• Arterial and antihypertensive effects of nitrendipine: a double-blind comparison versus placebo.

  Journal of cardiovascular pharmacology 19921201

• Adverse effect of the calcium channel blocker nitrendipine on nephrosclerosis in rats with renovascular hypertension.

  Hypertension (Dallas, Tex. : 1979) 19920801

• BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu), is a non-competitive antagonist of the actions of endothelin-1 in SK-N-MC human neuroblastoma cells.

  Biochemical and biophysical research communications 19920415

• Effect of antihypertensive treatment with nitrendipine on left ventricular mass and diastolic filling in patients with mild to moderate hypertension.

  Journal of cardiovascular pharmacology 19920101

• Effects of nitrendipine, chlordiazepoxide, flumazenil and baclofen on the increased anxiety resulting from alcohol withdrawal.

  Progress in neuro-psychopharmacology & biological psychiatry 19920101

• Pharmacokinetics, bioavailability, metabolism and acute and chronic antihypertensive effects of nitrendipine in patients with chronic renal failure and moderate to severe hypertension.

  British journal of clinical pharmacology 19910301

• The place of isradipine in the treatment of hypertension.

  American journal of hypertension 19910201

• Microvascular effects of cocaine; interaction with nitrendipine and enalaprilat.

  Journal of toxicology. Clinical toxicology 19910101

• Tolerance to nitrendipine in patients with arterial hypertension accompanying chronic renal failure.

  Journal of cardiovascular pharmacology 19910101

• Regression of cardiovascular structural changes after long-term antihypertensive treatment with the calcium antagonist nitrendipine.

  Journal of cardiovascular pharmacology 19910101

• Acute and short-term effects of nitrendipine and diltiazem at rest and during exercise in hypertensive patients.

  Clinical therapeutics 19910101

• Nitrendipine decreases benzodiazepine withdrawal seizures but not the development of benzodiazepine tolerance or withdrawal signs.

  British journal of pharmacology 19901101

• Lacidipine: a calcium antagonist with potent and long-lasting antihypertensive effects in animal studies.

  Journal of cardiovascular pharmacology 19900401

• Systemic and regional hemodynamic interactions of perindopril and nitrendipine in the spontaneously hypertensive rat.

  Journal of cardiovascular pharmacology 19900401

• Effects of nitrendipine and atenolol on blood pressure and intracellular sodium in hypertensive blacks.

  Journal of human hypertension 19900401

• Preclinical pharmacology of Ro 31-6930, a new potassium channel opener.

  Journal of cardiovascular pharmacology 19900201

• Role of N-methyl-D-aspartate (NMDA) receptors in experimental catalepsy in rats.

  Life sciences 19900101

• [The effect of calcium antagonist nitrendipine on the morphological picture of experimentally-produced myocardial injuries in rats].

  Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie 19900101

• Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.

  The Medical journal of Australia 19890904

• Cocaine-induced small vessel spasm in isolated rat hearts.

  The American journal of pathology 19890701

• Nitrendipine versus hydrochlorothiazide in hypertensive patients over 70 years of age.

  Clinical pharmacology and therapeutics 19890301

• Cosecretion of calcitonin and calcitonin gene-related peptide from cultured rat medullary thyroid C cells.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19890201

• Treatment of hypertension in the elderly with a new calcium channel blocking drug, nitrendipine.

  The American journal of medicine 19890101

• Felodipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension.

  Drugs 19881001

• Antihypertensive effect of felodipine or hydralazine when added to beta-blocker therapy.

  Journal of cardiovascular pharmacology 19880701

• Calcium currents in embryonic and neonatal mammalian skeletal muscle.

  The Journal of general physiology 19880601

• Effects of nitrendipine and cilazapril alone or in combination on hemodynamics and regional blood flows in conscious spontaneously hypertensive rats.

  Journal of cardiovascular pharmacology 19880101

• Short- and long-term cerebrovascular effects of nitrendipine in hypertensive patients.

  Journal of cardiovascular pharmacology 19880101

• A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.

  European journal of clinical pharmacology 19880101

• Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.

  Journal of clinical pharmacology 19871101

• Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.

  Journal of cardiovascular pharmacology 19871001

• MDL 72567, a dihydropyridine calcium-antagonist, that causes vasodilation and direct sinus bradycardia.

  Journal of cardiovascular pharmacology 19870701

• Nitrendipine-stimulated release of prostacyclin-like substance in normal and atherosclerotic animals.

  Arzneimittel-Forschung 19870401

• Renal effects of 1,4-dihydropyridines in animal models of hypertension and renal failure.

  Journal of cardiovascular pharmacology 19870101

• Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.

  Journal of cardiovascular pharmacology 19870101

• Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.

  Drugs 19870101

• Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.

  Drugs 19870101

• Felodipine compared to nifedipine as 'third-line drug' in resistant hypertension.

  Angiology 19861101

• Alteration of left ventricular diastolic filling in hypertensive patients: effects of nitrendipine and atenolol.

  European heart journal 19860901

• Relative potency of a beta-blocking and a calcium entry blocking agent as antihypertensive drugs in black patients.

  European journal of clinical pharmacology 19860101

• Predictors of blood pressure increases after withdrawal of antihypertensive therapy.

  Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201

• The protective effect of nitrendipine on gentamicin acute renal failure in rats.

  Experimental and molecular pathology 19850801

• Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.

  Journal of cardiovascular pharmacology 19850101

• Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.

  Proceedings of the National Academy of Sciences of the United States of America 19841001

• Clinical and systemic hemodynamic effects of nitrendipine.

  Clinical pharmacology and therapeutics 19840601

• Mode of antihypertensive action of nitrendipine.

  Journal of cardiovascular pharmacology 19840101

• Systemic and regional hemodynamics in normotensive and spontaneously hypertensive rats after slow-channel calcium blocker nitrendipine.

  Clinical and experimental hypertension. Part A, Theory and practice 19840101