39793-31-2 | 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$18.00	$13.00
1g	97%	in stock	$70.00	$49.00
5g	97%	in stock	$349.00	$244.00
10g	98%	in stock	$667.00	$467.00
25g	97%	in stock	$1,220.00	$854.00

Description

• Catalog Number: AD35758
• Chemical Name: 4H-Thieno[3,2-b]pyrrole-5-carboxylic acid
• CAS Number: 39793-31-2
• Molecular Formula: C7H5NO2S
• Molecular Weight: 167.1851
• MDL Number: MFCD07368542
• SMILES: OC(=O)c1cc2c([nH]1)ccs2

Computed Properties

• Complexity: 185
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.7

Literature

• A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats.

  The Journal of pharmacology and experimental therapeutics 20110101

• Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.

  Dialogues in clinical neuroscience 20100901

• Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.

  Bioorganic & medicinal chemistry 20100715

• The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors.

  The open medicinal chemistry journal 20100101

• Commentary: genome-based CNS drug discovery: D-amino acid oxidase (DAAO) as a novel target for antipsychotic medications: progress and challenges.

  Biochemical pharmacology 20091201

• The behavioral and neurochemical effects of a novel D-amino acid oxidase inhibitor compound 8 [4H-thieno [3,2-b]pyrrole-5-carboxylic acid] and D-serine.

  The Journal of pharmacology and experimental therapeutics 20090301

• The discovery of fused pyrrole carboxylic acids as novel, potent D-amino acid oxidase (DAO) inhibitors.

  Bioorganic & medicinal chemistry letters 20080601