39856-58-1 | 3-Amino-2-bromopyridine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$10.00	$7.00
10g	98%	in stock	$15.00	$10.00
25g	98%	in stock	$28.00	$19.00

Description

• Catalog Number: AB64190
• Chemical Name: 3-Amino-2-bromopyridine
• CAS Number: 39856-58-1
• Molecular Formula: C5H5BrN2
• Molecular Weight: 173.0106
• MDL Number: MFCD00234064
• SMILES: Nc1cccnc1Br

Computed Properties

• Complexity: 76.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.2

Upstream Synthesis Route

2-Bromopyridin-3-amine is a versatile chemical compound widely used in chemical synthesis as a crucial building block for the creation of various pharmaceuticals, agrochemicals, and advanced materials. Thanks to its unique structure and reactivity, 2-Bromopyridin-3-amine serves as a key intermediate in the synthesis of diverse organic molecules through its involvement in several important reactions.One of the primary applications of 2-Bromopyridin-3-amine lies in its ability to participate in cross-coupling reactions, particularly in Suzuki-Miyaura cross-coupling reactions. This reaction allows for the selective formation of carbon-carbon bonds between the bromoaryl group of 2-Bromopyridin-3-amine and different boronic acids or esters, leading to the generation of more complex and functionalized organic compounds. Additionally, the amino group present in 2-Bromopyridin-3-amine can undergo various functional group transformations, enabling further diversification of the synthesized molecules.Furthermore, 2-Bromopyridin-3-amine finds significant utility in the development of biologically active compounds and pharmaceuticals due to its presence in many drug molecules and natural products. By leveraging the synthetic potential of 2-Bromopyridin-3-amine, chemists can access novel molecular scaffolds and derivatives with improved properties, making it an invaluable tool in drug discovery and development efforts.In summary, the application of 2-Bromopyridin-3-amine in chemical synthesis encompasses its crucial role as a versatile building block for the construction of complex organic molecules, particularly in cross-coupling reactions and pharmaceutical synthesis. With its diverse reactivity and structural features, 2-Bromopyridin-3-amine continues to be instrumental in advancing the frontiers of organic chemistry and drug design.

Literature

• Molecular structure and vibrational spectra of 3-and 4-amino-2-bromopyridine by density functional methods.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120601