4021-07-2 | 3-Methylpicolinic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$8.00	$6.00
10g	97%	in stock	$11.00	$8.00
25g	95%	in stock	$13.00	$10.00

Description

• Catalog Number: AB44648
• Chemical Name: 3-Methylpicolinic acid
• CAS Number: 4021-07-2
• Molecular Formula: C7H7NO2
• Molecular Weight: 137.1360
• MDL Number: MFCD00191553
• SMILES: OC(=O)c1ncccc1C
• NSC Number: 109145

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.1

Upstream Synthesis Route

3-Methylpyridine-2-Carboxylic Acid, also known as picolinic acid, is a versatile compound widely used in various chemical synthesis processes. First and foremost, 3-Methylpyridine-2-Carboxylic Acid serves as a crucial building block in the synthesis of pharmaceutical compounds. Its unique chemical structure and reactivity make it an important intermediate in the production of various drugs and active pharmaceutical ingredients. Additionally, this compound is often employed in coordination chemistry as a chelating ligand. Due to its ability to coordinate with metal ions, 3-Methylpyridine-2-Carboxylic Acid is utilized in the synthesis of metal complexes and coordination polymers with diverse applications in catalysis and material science.Furthermore, 3-Methylpyridine-2-Carboxylic Acid is a key component in the preparation of metal-organic frameworks (MOFs). These porous materials have gained significant attention for their potential applications in gas storage, separation, and catalysis. The incorporation of this acid in the synthesis of MOFs contributes to the tunability of their properties and enhances their performance in various chemical processes.

Literature

• Poly[[diaqua-tris-(μ(2)-3-methyl-pyridine-2-carboxyl-ato)(3-methyl-pyridine-2-car-boxyl-ato)sodiumterbium(III)] ethanol monosolvate monohydrate].

  Acta crystallographica. Section E, Structure reports online 20101101

• catena-Poly[sodium [[tris(3-methyl-pyridine-2-carboxylato)europate(III)]-μ-3-methylpyridine-2-carboxylato] trihydrate].

  Acta crystallographica. Section E, Structure reports online 20100901

• Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3-methyl-picolinic acid.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100201

• Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene.

  Chembiochem : a European journal of chemical biology 20051201