407-41-0 | O-Phospho-l-serine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$30.00	$21.00
1g	95%	in stock	$33.00	$23.00
5g	95%	in stock	$84.00	$59.00
10g	95%	in stock	$151.00	$106.00
25g	95%	in stock	$255.00	$179.00
100g	95%	in stock	$955.00	$668.00

Description

• Catalog Number: AI49958
• Chemical Name: O-Phospho-l-serine
• CAS Number: 407-41-0
• Molecular Formula: C3H8NO6P
• Molecular Weight: 185.0725
• MDL Number: MFCD00065935
• SMILES: OC(=O)C(COP(=O)(O)O)N
• NSC Number: 760136

Computed Properties

• Complexity: 186
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 4
• XLogP3: -5.1

Literature

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• Proteomic characterization of ovarian cancers identifying annexin-A4, phosphoserine aminotransferase, cellular retinoic acid-binding protein 2, and serpin B5 as histology-specific biomarkers.

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• Phosphorylation status of matrix metalloproteinase 2 in myocardial ischaemia-reperfusion injury.

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• Dephosphorylation of circulating human osteopontin correlates with severe valvular calcification in patients with calcific aortic valve disease.

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• Translation initiation factor eIF-5A, the hypusine-containing protein, is phosphorylated on serine and tyrosine and O-glycosylated in Trichomonas vaginalis.

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• Insights into the regulation of eukaryotic elongation factor 2 kinase and the interplay between its domains.

  The Biochemical journal 20120215

• Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.

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• Receptor-mediated modulation of activity-dependent adenosine release in rat cerebellum.

  Neuropharmacology 20120201

• Genotyping of Streptococcus thermophilus strains isolated from traditional Egyptian dairy products by sequence analysis of the phosphoserine phosphatase (serB) gene with phenotypic characterizations of the strains.

  Journal of applied microbiology 20120201

• Enterocyte STAT5 promotes mucosal wound healing via suppression of myosin light chain kinase-mediated loss of barrier function and inflammation.

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• Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserine.

  The Journal of biological chemistry 20120113

• Role of Cdc14 in timing the end of cell division: Cdc14 phosphatases preferentially dephosphorylate a subset of cyclin-dependent kinase (Cdk) sites containing phosphoserine.

  The Journal of biological chemistry 20120113

• Cysteinyl leukotriene type I receptor desensitization sustains Ca2+-dependent gene expression.

  Nature 20120109

• Divergence and convergence in enzyme evolution.

  The Journal of biological chemistry 20120102

• Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines.

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• Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

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• Expression of the maize ZmGF14-6 gene in rice confers tolerance to drought stress while enhancing susceptibility to pathogen infection.

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• Effects of a Chinese Herbal Medicine, Guan-Jen-Huang (Aeginetia indica Linn.), on Renal Cancer Cell Growth and Metastasis.

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• The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation.

  Nature immunology 20120101

• Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia.

  Autophagy 20120101

• Alcohol Activates TGF-Beta but Inhibits BMP Receptor-Mediated Smad Signaling and Smad4 Binding to Hepcidin Promoter in the Liver.

  International journal of hepatology 20120101

• Casein phosphopeptides drastically increase the secretion of extracellular proteins in Aspergillus awamori. Proteomics studies reveal changes in the secretory pathway.

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• Using the Tg(nrd:egfp)/albino zebrafish line to characterize in vivo expression of neurod.

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• Knockdown of menin affects pre-mRNA processing and promoter fidelity at the interferon-gamma inducible IRF1 gene.

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• 5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability.

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• GSK3 as a Sensor Determining Cell Fate in the Brain.

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• Ser-634 and Ser-636 of Kaposi's Sarcoma-Associated Herpesvirus RTA are Involved in Transactivation and are Potential Cdk9 Phosphorylation Sites.

  Frontiers in microbiology 20120101

• Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.

  Molecular systems biology 20120101

• Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization.

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• Identification of a novel signaling pathway and its relevance for GluA1 recycling.

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• Cortactin tyrosine phosphorylation promotes its deacetylation and inhibits cell spreading.

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• Molecular cloning and in silico analysis of the duck (Anas platyrhynchos) MEF2A gene cDNA and its expression profile in muscle tissues during fetal development.

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• Systematic identification of spontaneous preterm birth-associated RNA transcripts in maternal plasma.

  PloS one 20120101

• PKC-Mediated ZYG1 Phosphorylation Induces Fusion of Myoblasts as well as of Dictyostelium Cells.

  International journal of cell biology 20120101

• The effect of α- or β-casein addition to waxy maize starch on postprandial levels of glucose, insulin, and incretin hormones in pigs as a model for humans.

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• Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling.

  PloS one 20120101

• Phosphorylation of intrinsically disordered regions in remorin proteins.

  Frontiers in plant science 20120101

• Spectrofluorimetric determination of human serum albumin using terbium-danofloxacin probe.

  TheScientificWorldJournal 20120101

• Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.

  PloS one 20120101

• Metabolic profiling of the protozoan parasite Entamoeba invadens revealed activation of unpredicted pathway during encystation.

  PloS one 20120101

• Cdc42-dependent activation of NADPH oxidase is involved in ethanol-induced neuronal oxidative stress.

  PloS one 20120101

• Discovering the phosphoproteome of the hydrophobic cytochrome c oxidase membrane protein complex.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Identification of functional differences in metabolic networks using comparative genomics and constraint-based models.

  PloS one 20120101

• Intranasal 'painless' human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice.

  PloS one 20120101

• Cortactin is involved in the entry of Coxiella burnetii into non-phagocytic cells.

  PloS one 20120101

• Improvement of probe peptides for coiled-coil labeling by introducing phosphoserines.

  Biopolymers 20120101

• Analysis of PSPHL as a Candidate Gene Influencing the Racial Disparity in Endometrial Cancer.

  Frontiers in oncology 20120101

• Tyrosine Phosphorylation of the BRI1 Receptor Kinase Occurs via a Post-Translational Modification and is Activated by the Juxtamembrane Domain.

  Frontiers in plant science 20120101

• Effect of asynchronous transfer on bovine embryonic development and relationship with early cycle uterine proteome profiles.

  Reproduction, fertility, and development 20120101

• The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

  Molecular cell 20111223

• MAPKKK-independent regulation of the Hog1 stress-activated protein kinase in Candida albicans.

  The Journal of biological chemistry 20111209

• Phosphorylation and interaction of myopodin by integrin-link kinase lead to suppression of cell growth and motility in prostate cancer cells.

  Oncogene 20111208

• Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling.

  Journal of proteome research 20111202

• High affinity group III mGluRs regulate mossy fiber input to CA3 interneurons.

  Hippocampus 20111201

• Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast.

  Nature structural & molecular biology 20111201

• The FGFR4-G388R polymorphism promotes mitochondrial STAT3 serine phosphorylation to facilitate pituitary growth hormone cell tumorigenesis.

  PLoS genetics 20111201

• Matrix Gla protein inhibits ectopic calcification by a direct interaction with hydroxyapatite crystals.

  Journal of the American Chemical Society 20111116

• Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways.

  The Journal of biological chemistry 20111104

• Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice.

  Molecular psychiatry 20111101

• Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation.

  Human molecular genetics 20111101

• Chromatin affinity purification and quantitative mass spectrometry defining the interactome of histone modification patterns.

  Molecular & cellular proteomics : MCP 20111101

• A proteomic analysis of the chromoplasts isolated from sweet orange fruits [Citrus sinensis (L.) Osbeck].

  Journal of experimental botany 20111101

• Doxorubicin-induced platelet procoagulant activities: an important clue for chemotherapy-associated thrombosis.

  Toxicological sciences : an official journal of the Society of Toxicology 20111101

• Tomato SlSnRK1 protein interacts with and phosphorylates βC1, a pathogenesis protein encoded by a geminivirus β-satellite.

  Plant physiology 20111101

• Structural and functional assays of AtTLP18.3 identify its novel acid phosphatase activity in thylakoid lumen.

  Plant physiology 20111101

• Computational modeling of the catalytic mechanism of human placental alkaline phosphatase (PLAP).

  Journal of chemical information and modeling 20111024

• Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.

  The EMBO journal 20111019

• An optical switch for a motor protein.

  Chembiochem : a European journal of chemical biology 20111017

• Tumor necrosis factor-α activates estrogen signaling pathways in endometrial epithelial cells via estrogen receptor α.

  Molecular and cellular endocrinology 20111015

• 14-3-3 Binding to ataxin-1(ATXN1) regulates its dephosphorylation at Ser-776 and transport to the nucleus.

  The Journal of biological chemistry 20111007

• Understanding protein kinase CK2 mis-regulation upon F508del CFTR expression.

  Naunyn-Schmiedeberg's archives of pharmacology 20111001

• Phosphorylation of maize eukaryotic translation initiation factor on Ser2 by catalytic subunit CK2.

  Molecular and cellular biochemistry 20111001

• Induction and activation of the p53 pathway: a role for the protein kinase CK2?

  Molecular and cellular biochemistry 20111001

• Phosphatase and tensin homolog on chromosome 10 is phosphorylated in primary effusion lymphoma and Kaposi's sarcoma.

  The American journal of pathology 20111001

• Dysregulation of serine biosynthesis contributes to the growth defect of a Mycobacterium tuberculosis crp mutant.

  Molecular microbiology 20111001

• OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer.

  Cell death & disease 20111001

• RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus.

  PLoS pathogens 20111001

• The Effects of Glyburide on Apoptosis and Endoplasmic Reticulum Stress in INS-1 Cells in a Glucolipotoxic Condition.

  Diabetes & metabolism journal 20111001

• Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5.

  The Journal of biological chemistry 20110923

• Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation.

  Nature 20110922

• Determination of a phosphorylation site in Nipah virus nucleoprotein and its involvement in virus transcription.

  The Journal of general virology 20110901

• EGF-induced ERK-activation downstream of FAK requires rac1-NADPH oxidase.

  Journal of cellular physiology 20110901

• R-Ras interacts with filamin a to maintain endothelial barrier function.

  Journal of cellular physiology 20110901

• L-3-Phosphoserine phosphatase (PSPH) regulates cutaneous squamous cell carcinoma proliferation independent of L-serine biosynthesis.

  Journal of dermatological science 20110901

• Modelling of the gas-phase phosphate group loss and rearrangement in phosphorylated peptides.

  Journal of mass spectrometry : JMS 20110901

• Study of FoxA pioneer factor at silent genes reveals Rfx-repressed enhancer at Cdx2 and a potential indicator of esophageal adenocarcinoma development.

  PLoS genetics 20110901

• A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence.

  PLoS pathogens 20110901

• The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.

  The EMBO journal 20110831

• A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes.

  Journal of molecular biology 20110826

• Expanding the genetic code of Escherichia coli with phosphoserine.

  Science (New York, N.Y.) 20110826

• Solution structure of tandem SH2 domains from Spt6 protein and their binding to the phosphorylated RNA polymerase II C-terminal domain.

  The Journal of biological chemistry 20110819

• Cyclin-dependent kinase 1 (CDK1)-mediated phosphorylation of enhancer of zeste 2 (Ezh2) regulates its stability.

  The Journal of biological chemistry 20110812

• NMR spectroscopy of 14-3-3ζ reveals a flexible C-terminal extension: differentiation of the chaperone and phosphoserine-binding activities of 14-3-3ζ.

  The Biochemical journal 20110801

• DMP1 and DSPP: evidence for duplication and convergent evolution of two SIBLING proteins.

  Cells, tissues, organs 20110801

• Suppression of AMPK activation via S485 phosphorylation by IGF-I during hyperglycemia is mediated by AKT activation in vascular smooth muscle cells.

  Endocrinology 20110801

• Understanding non-enzymatic aminophospholipid glycation and its inhibition. Polar head features affect the kinetics of Schiff base formation.

  Bioorganic & medicinal chemistry 20110801

• Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity.

  Nature immunology 20110801

• Longevity and stress in Caenorhabditis elegans.

  Aging 20110801

• Forkhead-associated (FHA) domain containing ABC transporter Rv1747 is positively regulated by Ser/Thr phosphorylation in Mycobacterium tuberculosis.

  The Journal of biological chemistry 20110722

• Gimme phospho-serine five! Capping enzyme guanylyltransferase recognition of the RNA polymerase II CTD.

  Molecular cell 20110722

• Tandem mass spectrometric method for definitive localization of phosphorylation sites using bromine signature.

  Analytical biochemistry 20110715

• Nicotinamide attenuates the ischemic brain injury-induced decrease of Akt activation and Bad phosphorylation.

  Neuroscience letters 20110708

• ADP-ribosylation of arginine.

  Amino acids 20110701

• MC3T3-E1 cell differentiation and in vivo bone formation induced by phosphoserine.

  Biotechnology letters 20110701

• SAD phasing using iodide ions in a high-throughput structural genomics environment.

  Journal of structural and functional genomics 20110701

• Phosphorylation of human calsequestrin: implications for calcium regulation.

  Molecular and cellular biochemistry 20110701

• The tumor suppressor gene Trp53 protects the mouse lens against posterior subcapsular cataracts and the BMP receptor Acvr1 acts as a tumor suppressor in the lens.

  Disease models & mechanisms 20110701

• Nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase is phosphorylated in wheat endosperm at serine-404 by an SNF1-related protein kinase allosterically inhibited by ribose-5-phosphate.

  Plant physiology 20110701

• CmRBP50 protein phosphorylation is essential for assembly of a stable phloem-mobile high-affinity ribonucleoprotein complex.

  The Journal of biological chemistry 20110701

• Synaptotagmin-1 may be a distance regulator acting upstream of SNARE nucleation.

  Nature structural & molecular biology 20110701

• Recognition of the F&H motif by the Lowe syndrome protein OCRL.

  Nature structural & molecular biology 20110701

• Amniotic fluid amino acid levels in non-immune hydrops fetalis: a case-control study.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110701

• Reaction of cresyl saligenin phosphate, the organophosphorus agent implicated in aerotoxic syndrome, with human cholinesterases: mechanistic studies employing kinetics, mass spectrometry, and X-ray structure analysis.

  Chemical research in toxicology 20110620

• Particle stimulation dephosphorylates glutathione S-transferase π1 of epithelial cells.

  Toxicology 20110618

• Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+.

  The Journal of biological chemistry 20110617

• A Smad action turnover switch operated by WW domain readers of a phosphoserine code.

  Genes & development 20110615

• Light-triggered myosin activation for probing dynamic cellular processes.

  Angewandte Chemie (International ed. in English) 20110614

• Quantitative analysis of cytokine-induced hepatocyte nuclear factor-4α phosphorylation by mass spectrometry.

  Biochemistry 20110614

• Antibody-free peptide substrate screening of serine/threonine kinase (protein kinase A) with a biotinylated detection probe.

  Analytical biochemistry 20110601

• Complex phosphorylation dynamics control the composition of the Syk interactome in B cells.

  European journal of immunology 20110601

• Eukaryotic-like Ser/Thr protein kinases SpkC/F/K are involved in phosphorylation of GroES in the Cyanobacterium synechocystis.

  DNA research : an international journal for rapid publication of reports on genes and genomes 20110601

• Serine-phosphoric acid cluster ions studied by electrospray ionization and tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20110601

• Phosphorylation of AKT: a mutational analysis.

  Oncotarget 20110601

• Move or die: the fate of the Tax oncoprotein of HTLV-1.

  Viruses 20110601

• Impact of BRCA1 BRCT domain missense substitutions on phosphopeptide recognition.

  Biochemistry 20110531

• Enzyme-linked immunosorbent assay for detection of organophosphorylated butyrylcholinesterase: a biomarker of exposure to organophosphate agents.

  Analytica chimica acta 20110505

• Biophysical characterization of Entamoeba histolytica phosphoserine aminotransferase (EhPSAT): role of cofactor and domains in stability and subunit assembly.

  European biophysics journal : EBJ 20110501

• HSC70 blockade by the therapeutic peptide P140 affects autophagic processes and endogenous MHCII presentation in murine lupus.

  Annals of the rheumatic diseases 20110501

• GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions.

  Angiogenesis 20110501

• Reversible phosphorylation regulation of NADPH-linked polyol dehydrogenase in the freeze-avoiding gall moth, Epiblema scudderiana: role in glycerol metabolism.

  Archives of insect biochemistry and physiology 20110501

• ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes.

  Nature immunology 20110501

• An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.

  PLoS pathogens 20110501

• An acidic loop and cognate phosphorylation sites define a molecular switch that modulates ubiquitin charging activity in Cdc34-like enzymes.

  PLoS computational biology 20110501

• Mutations in the BRCT binding site of BRCA1 result in hyper-recombination.

  Aging 20110501

• Homo sapiens dullard protein phosphatase shows a preference for the insulin-dependent phosphorylation site of lipin1.

  Biochemistry 20110419

• Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease.

  The Journal of biological chemistry 20110408

• Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production.

  Amino acids 20110401

• Metformin induces Rab4 through AMPK and modulates GLUT4 translocation in skeletal muscle cells.

  Journal of cellular physiology 20110401

• Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code.

  The Journal of biological chemistry 20110401

• Biliverdin reductase--a protein levels and activity in the brains of subjects with Alzheimer disease and mild cognitive impairment.

  Biochimica et biophysica acta 20110401

• OX40 engagement stabilizes Mxd4 and Mnt protein levels in antigen-stimulated T cells leading to an increase in cell survival.

  European journal of immunology 20110401

• Dipole-guided electron capture causes abnormal dissociations of phosphorylated pentapeptides.

  Journal of the American Society for Mass Spectrometry 20110401

• Cell-type-specific regulation of raft-associated Akt signaling.

  Cell death & disease 20110401

• The MARCH family E3 ubiquitin ligase K5 alters monocyte metabolism and proliferation through receptor tyrosine kinase modulation.

  PLoS pathogens 20110401

• Depletion of Ku70/80 reduces the levels of extrachromosomal telomeric circles and inhibits proliferation of ALT cells.

  Aging 20110401

• Gene expression regulation through 14-3-3 interactions with histones and HDACs.

  Discovery medicine 20110401

• Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis.

  Oncogene 20110331

• Fluorescence spectroscopy as a probe of the effect of phosphorylation at serine 40 of tyrosine hydroxylase on the conformation of its regulatory domain.

  Biochemistry 20110329

• Structure and stabilizing interactions of casein micelles probed by high-pressure light scattering and FTIR.

  The journal of physical chemistry. B 20110317

• Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response.

  The EMBO journal 20110302

• INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis.

  Cell death and differentiation 20110301

• Integration of proteomic analyses to monitor the activity status of phosphorylation signaling.

  Journal of proteomics 20110301

• A robust protocol to map binding sites of the 14-3-3 interactome: Cdc25C requires phosphorylation of both S216 and S263 to bind 14-3-3.

  Molecular & cellular proteomics : MCP 20110301

• Rapid analysis of phosphoamino acids from phosvitin by near-infrared cyanine 1-(ε-succinimydyl-hexanoate)-1'-methyl-3,3,3',3'-tetramethyl-indocarbocyanine-5,5'-disulfonate potassium derivatization and polyacrylamide-coated CE with LIF detection.

  Electrophoresis 20110301

• Global analysis of the relationship between JIL-1 kinase and transcription.

  PLoS genetics 20110301

• A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line.

  PLoS genetics 20110301

• Biosynthesis of selenocysteine, the 21st amino acid in the genetic code, and a novel pathway for cysteine biosynthesis.

  Advances in nutrition (Bethesda, Md.) 20110301

• IKKε regulates cell elongation through recycling endosome shuttling.

  Developmental cell 20110215

• Mechanistic studies of Ser/Thr dehydration catalyzed by a member of the LanL lanthionine synthetase family.

  Biochemistry 20110208

• MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.

  Nature 20110203

• mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn.

  Burns : journal of the International Society for Burn Injuries 20110201

• Epigenetic control of vascular smooth muscle cells in Marfan and non-Marfan thoracic aortic aneurysms.

  Cardiovascular research 20110201

• A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression.

  Neuroscience research 20110201

• Genetics of photoreceptor degeneration and regeneration in zebrafish.

  Cellular and molecular life sciences : CMLS 20110201

• Removal or masking of phosphatidylinositol(4,5)bisphosphate from the outer mitochondrial membrane causes mitochondrial fragmentation.

  Cellular signalling 20110201

• Serine phosphorylation of NPM-ALK, which is dependent on the auto-activation of the kinase activation loop, contributes to its oncogenic potential.

  Carcinogenesis 20110201

• Pin1 prolyl isomerase regulates endothelial nitric oxide synthase.

  Arteriosclerosis, thrombosis, and vascular biology 20110201

• Functionalized graphene oxide as a nanocarrier in a multienzyme labeling amplification strategy for ultrasensitive electrochemical immunoassay of phosphorylated p53 (S392).

  Analytical chemistry 20110201

• Effect of inhibition of spinal cord glutamate transporters on inflammatory pain induced by formalin and complete Freund's adjuvant.

  Anesthesiology 20110201

• Regulation of yeast Yak1 kinase by PKA and autophosphorylation-dependent 14-3-3 binding.

  Molecular microbiology 20110201

• NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly.

  PLoS pathogens 20110201

• Analysis of gene expression during mineralization of cultured human periodontal ligament cells.

  Journal of periodontal & implant science 20110201

• Geometrically associative yet electronically dissociative character in the transition state of enzymatic reversible phosphorylation.

  Journal of computational chemistry 20110130

• Ferric ions inhibit proteolytic processing of progastrin.

  Biochemical and biophysical research communications 20110128

• Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.

  The Journal of biological chemistry 20110107

• Proteomic analysis of native hepatocyte nuclear factor-4α (HNF4α) isoforms, phosphorylation status, and interactive cofactors.

  The Journal of biological chemistry 20110107

• Role of MSK1 in the malignant phenotype of Ras-transformed mouse fibroblasts.

  The Journal of biological chemistry 20110107

• 3-Phosphono-L-alanine as pyrophosphate mimic for DNA synthesis using HIV-1 reverse transcriptase.

  Organic & biomolecular chemistry 20110107

• Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.

  Breast cancer research and treatment 20110101

• Phosphoserine-modified calcium phosphate cements: bioresorption and substitution.

  Journal of tissue engineering and regenerative medicine 20110101

• Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes.

  Molecular & cellular proteomics : MCP 20110101

• Osmotic stress stimulates phosphorylation and cellular expression of heat shock proteins in rhesus macaque sperm.

  Journal of andrology 20110101

• Light-induced phosphorylation of crystallins in the retinal pigment epithelium.

  International journal of biological macromolecules 20110101

• Increased expression of PIN1 gene in papillary thyroid carcinoma.

  Thyroid research 20110101

• Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer.

  BMC medicine 20110101

• New proteins found interacting with brain metallothionein-3 are linked to secretion.

  International journal of Alzheimer's disease 20110101

• De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth.

  PloS one 20110101

• Escharectomy and allografting during shock stage reduces insulin resistance induced by major burn.

  Journal of burn care & research : official publication of the American Burn Association 20110101

• Structural basis for the recognition of cellular mRNA export factor REF by herpes viral proteins HSV-1 ICP27 and HVS ORF57.

  PLoS pathogens 20110101

• Reverse transcription of the pFOXC mitochondrial retroplasmids of Fusarium oxysporum is protein primed.

  Mobile DNA 20110101

• An ancient family of SelB elongation factor-like proteins with a broad but disjunct distribution across archaea.

  BMC evolutionary biology 20110101

• Issues associated with the use of phosphospecific antibodies to localise active and inactive pools of GSK-3 in cells.

  Biology direct 20110101

• Phosphoproteomics characterization of novel phosphorylated sites of lens proteins from normal and cataractous human eye lenses.

  Molecular vision 20110101

• Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn.

  Molecular neurodegeneration 20110101

• Porcine dentin sialoprotein glycosylation and glycosaminoglycan attachments.

  BMC biochemistry 20110101

• Impaired desensitization of a human polymorphic α2B-adrenergic receptor variant enhances its sympatho-inhibitory activity in chromaffin cells.

  Cell communication and signaling : CCS 20110101

• Bacillus subtilis two-component system sensory kinase DegS is regulated by serine phosphorylation in its input domain.

  PloS one 20110101

• Activation of the canonical Wnt/β-catenin pathway in ATF3-induced mammary tumors.

  PloS one 20110101

• Evolutionary patterns of phosphorylated serines.

  Biology direct 20110101

• Histone deacetylase activity modulates alternative splicing.

  PloS one 20110101

• Prolyl isomerase pin1 protects mice from endotoxin shock.

  PloS one 20110101

• Distinct colonization patterns and cDNA-AFLP transcriptome profiles in compatible and incompatible interactions between melon and different races of Fusarium oxysporum f. sp. melonis.

  BMC genomics 20110101

• TGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors.

  BMC molecular biology 20110101

• Two TPX2-dependent switches control the activity of Aurora A.

  PloS one 20110101

• Changes in expression of VE-cadherin and MMPs in endothelial cells: Implications for angiogenesis.

  Vascular cell 20110101

• Changes in gene expression and cellular architecture in an ovarian cancer progression model.

  PloS one 20110101

• Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease.

  PloS one 20110101

• Role of p53 serine 46 in p53 target gene regulation.

  PloS one 20110101

• New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform.

  PloS one 20110101

• Unfolding of the amyloid β-peptide central helix: mechanistic insights from molecular dynamics simulations.

  PloS one 20110101

• TACE/ADAM-17 phosphorylation by PKC-epsilon mediates premalignant changes in tobacco smoke-exposed lung cells.

  PloS one 20110101

• Genomic heterogeneity within conservedmetabolic pathways of Arthrobacter species - a bioinformatic approach.

  Bioinformation 20110101

• Evolution of parallel spindles like genes in plants and highlight of unique domain architecture#.

  BMC evolutionary biology 20110101

• Structural analysis of alkaline β-mannanase from alkaliphilic Bacillus sp. N16-5: implications for adaptation to alkaline conditions.

  PloS one 20110101

• Oncogene activation induces metabolic transformation resulting in insulin-independence in human breast cancer cells.

  PloS one 20110101

• The serine 814 of TRPC6 is phosphorylated under unstimulated conditions.

  PloS one 20110101

• A database of thermodynamic properties of the reactions of glycolysis, the tricarboxylic acid cycle, and the pentose phosphate pathway.

  Database : the journal of biological databases and curation 20110101

• Quantitative mass spectrometry analysis reveals similar substrate consensus motif for human Mps1 kinase and Plk1.

  PloS one 20110101

• Genomic comparison of invasive and rare non-invasive strains reveals Porphyromonas gingivalis genetic polymorphisms.

  Journal of oral microbiology 20110101

• Isolation and mutagenesis of a capsule-like complex (CLC) from Francisella tularensis, and contribution of the CLC to F. tularensis virulence in mice.

  PloS one 20110101

• Survey of activated FLT3 signaling in leukemia.

  PloS one 20110101

• IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein kinase 2.

  PloS one 20110101

• Rac1 deletion causes thymic atrophy.

  PloS one 20110101

• Different conformations of phosphatase and tensin homolog, deleted on chromosome 10 (PTEN) protein within the nucleus and cytoplasm of neurons.

  PloS one 20110101

• Induction of TLR-2 and TLR-5 expression by Helicobacter pylori switches cagPAI-dependent signalling leading to the secretion of IL-8 and TNF-α.

  PloS one 20110101

• Identification of phosphoproteins as possible differentiation markers in all-trans-retinoic acid-treated neuroblastoma cells.

  PloS one 20110101

• Theoretical study of bone sialoprotein in bone biomineralization.

  Cells, tissues, organs 20110101

• Mechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular Dynamics.

  BMC biophysics 20110101

• Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica.

  BMC genomics 20110101

• Crystal structure analysis reveals functional flexibility in the selenocysteine-specific tRNA from mouse.

  PloS one 20110101

• What Are the bona fide GSK3 Substrates?

  International journal of Alzheimer's disease 20110101

• Clinical and technical phosphoproteomic research.

  Proteome science 20110101

• BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

  PloS one 20110101

• Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.

  PloS one 20110101

• Prognostic association of YB-1 expression in breast cancers: a matter of antibody.

  PloS one 20110101

• EST mining identifies proteins putatively secreted by the anthracnose pathogen Colletotrichum truncatum.

  BMC genomics 20110101

• PlantPhos: using maximal dependence decomposition to identify plant phosphorylation sites with substrate site specificity.

  BMC bioinformatics 20110101

• Reversal of endocrine resistance in breast cancer: interrelationships among 14-3-3ζ, FOXM1, and a gene signature associated with mitosis.

  Breast cancer research : BCR 20110101

• Phosphoproteins regulated by heat stress in rice leaves.

  Proteome science 20110101

• Nutritional deficiencies and phospholipid metabolism.

  International journal of molecular sciences 20110101

• Radioactive phosphorylation of alcohols to monitor biocatalytic Diels-Alder reactions.

  PloS one 20110101

• Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

  PloS one 20110101

• Detailed regulatory mechanism of the interaction between ZO-1 PDZ2 and connexin43 revealed by MD simulations.

  PloS one 20110101

• Spinning gland transcriptomics from two main clades of spiders (order: Araneae)--insights on their molecular, anatomical and behavioral evolution.

  PloS one 20110101

• Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1).

  PloS one 20110101

• PP1 forms an active complex with TLRR (lrrc67), a putative PP1 regulatory subunit, during the early stages of spermiogenesis in mice.

  PloS one 20110101

• Liver Metabolic Alterations and Changes in Host Intercompartmental Metabolic Correlation during Progression of Malaria.

  Journal of parasitology research 20110101

• Functional Diversity of the Schistosoma mansoni Tyrosine Kinases.

  Journal of signal transduction 20110101

• Sticky and sweet: the role of post-translational modifications on neisserial pili.

  Frontiers in microbiology 20110101

• The minimal kinome of Giardia lamblia illuminates early kinase evolution and unique parasite biology.

  Genome biology 20110101

• Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.

  PloS one 20110101

• Interleukin-4 alters early phagosome phenotype by modulating class I PI3K dependent lipid remodeling and protein recruitment.

  PloS one 20110101

• The hepatitis E virus ORF3 protein regulates the expression of liver-specific genes by modulating localization of hepatocyte nuclear factor 4.

  PloS one 20110101

• [Modeling the transition state of enzyme-catalyzed phosphoryl transfer reaction using QM/MM method].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101

• Specific and nonhomologous isofunctional enzymes of the genetic information processing pathways as potential therapeutical targets for tritryps.

  Enzyme research 20110101

• Functional Evolution of BRCT Domains from Binding DNA to Protein.

  Evolutionary bioinformatics online 20110101

• CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton.

  PloS one 20110101

• Characterization of Leishmania donovani MCM4: expression patterns and interaction with PCNA.

  PloS one 20110101

• Interactions with Host Cells Causes Neisseria meningitidis Pili to Become Unglued.

  Frontiers in microbiology 20110101

• Characterization of 14-3-3 proteins from Cryptosporidium parvum.

  PloS one 20110101

• Evaluating experimental bias and completeness in comparative phosphoproteomics analysis.

  PloS one 20110101

• Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.

  PloS one 20110101

• Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line.

  Journal of biomedicine & biotechnology 20110101

• Drosophila selenophosphate synthetase 1 regulates vitamin B6 metabolism: prediction and confirmation.

  BMC genomics 20110101

• Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90.

  Molecular cancer 20110101

• Discovering and validating unknown phospho-sites from p38 and HuR protein kinases in vitro by Phosphoproteomic and Bioinformatic tools.

  Journal of clinical bioinformatics 20110101

• High density lipoprotein (HDL) promotes glucose uptake in adipocytes and glycogen synthesis in muscle cells.

  PloS one 20110101

• Critical role of PI3K/Akt/GSK3β in motoneuron specification from human neural stem cells in response to FGF2 and EGF.

  PloS one 20110101

• CK2 phosphorylation of Schistosoma mansoni HMGB1 protein regulates its cellular traffic and secretion but not its DNA transactions.

  PloS one 20110101

• Synaptic reorganization in the adult rat's ventral cochlear nucleus following its total sensory deafferentation.

  PloS one 20110101

• Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA.

  PloS one 20110101

• Phosphorylcholine Phosphatase: A Peculiar Enzyme of Pseudomonas aeruginosa.

  Enzyme research 20110101

• Phosphorylation provides a negative mode of regulation for the yeast Rab GTPase Sec4p.

  PloS one 20110101

• Aberrant upregulation of 14-3-3ơ expression serves as an inferior prognostic biomarker for gastric cancer.

  BMC cancer 20110101

• Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells.

  PloS one 20110101

• Quantitative phosphoproteomics of CXCL12 (SDF-1) signaling.

  PloS one 20110101

• Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression.

  PloS one 20110101

• Structural studies of the PARP-1 BRCT domain.

  BMC structural biology 20110101

• Technical phosphoproteomic and bioinformatic tools useful in cancer research.

  Journal of clinical bioinformatics 20110101

• Prenatal cocaine exposure increases synaptic localization of a neuronal RasGEF, GRASP-1 via hyperphosphorylation of AMPAR anchoring protein, GRIP.

  PloS one 20110101

• Skin healing and scale regeneration in fed and unfed sea bream, Sparus auratus.

  BMC genomics 20110101

• CcpA represses the expression of the divergent cit operons of Enterococcus faecalis through multiple cre sites.

  BMC microbiology 20110101

• Challenges in the association of human single nucleotide polymorphism mentions with unique database identifiers.

  BMC bioinformatics 20110101

• SUMOylation of the Forkhead transcription factor FOXL2 promotes its stabilization/activation through transient recruitment to PML bodies.

  PloS one 20110101

• Progesterone-induced changes in the phosphoryl potential during the meiotic divisions in amphibian oocytes: role of Na/K-ATPase.

  BMC developmental biology 20110101

• GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS.

  Frontiers in molecular neuroscience 20110101

• Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation.

  PloS one 20110101

• Integrated epigenetics of human breast cancer: synoptic investigation of targeted genes, microRNAs and proteins upon demethylation treatment.

  PloS one 20110101

• Dynamic expression of synemin isoforms in mouse embryonic stem cells and neural derivatives.

  BMC cell biology 20110101

• GSK-3: Functional Insights from Cell Biology and Animal Models.

  Frontiers in molecular neuroscience 20110101

• The multi-level action of fatty acids on adiponectin production by fat cells.

  PloS one 20110101

• Elucidation of the dual role of Mycobacterial MoeZR in molybdenum cofactor biosynthesis and cysteine biosynthesis.

  PloS one 20110101

• SUMO-SIM interactions regulate the activity of RGSZ2 proteins.

  PloS one 20110101

• Pectenotoxin-2 from marine sponges: a potential anti-cancer agent-a review.

  Marine drugs 20110101

• Drosophila melanogaster dHCF interacts with both PcG and TrxG epigenetic regulators.

  PloS one 20110101

• XPA-mediated regulation of global nucleotide excision repair by ATR Is p53-dependent and occurs primarily in S-phase.

  PloS one 20110101

• Cancer's sweet tooth for serine.

  Breast cancer research : BCR 20110101

• Susceptibility to dental caries and the salivary proline-rich proteins.

  International journal of dentistry 20110101

• Differential phosphorylation of ribosomal proteins in Arabidopsis thaliana plants during day and night.

  PloS one 20110101

• Nitric oxide, erythrocytes and exercise.

  Clinical hemorheology and microcirculation 20110101

• Expressed sequence tag analysis of khat (Catha edulis) provides a putative molecular biochemical basis for the biosynthesis of phenylpropylamino alkaloids.

  Genetics and molecular biology 20110101

• Phosphorylation and activation of the plasma membrane Na+/H+ exchanger (NHE1) during osmotic cell shrinkage.

  PloS one 20110101

• Fast disintegrating tablets: Opportunity in drug delivery system.

  Journal of advanced pharmaceutical technology & research 20110101

• Dynamics of protein phosphatase gene expression in Corbicula fluminea exposed to microcystin-LR and to toxic Microcystis aeruginosa cells.

  International journal of molecular sciences 20110101

• The human c1q globular domain: structure and recognition of non-immune self ligands.

  Frontiers in immunology 20110101

• Landmarks in insulin research.

  Frontiers in endocrinology 20110101

• Allosteric regulation of glycogen synthase kinase 3β: a theoretical study.

  Biochemistry 20101228

• p38 maintains E-cadherin expression by modulating TAK1-NF-kappa B during epithelial-to-mesenchymal transition.

  Journal of cell science 20101215

• Metabolomics of gastric cancer metastasis detected by gas chromatography and mass spectrometry.

  World journal of gastroenterology 20101214

• FHA domain pThr binding specificity: it's all about me.

  Structure (London, England : 1993) 20101208

• Structural and functional analysis of phosphothreonine-dependent FHA domain interactions.

  Structure (London, England : 1993) 20101208

• Positional effects of phosphoserine on β-hairpin stability.

  Organic & biomolecular chemistry 20101207

• Electron capture dissociation mass spectrometric analysis of lysine-phosphorylated peptides.

  Bioscience reports 20101201

• Functional relevance of the IRF-1 promoter polymorphism rs2549009 on transcriptional activity in a native genomic environment.

  Human molecular genetics 20101201

• Uncovering new substrates for Aurora A kinase.

  EMBO reports 20101201

• In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation.

  Biophysical journal 20101201

• Inhibition of constitutive activation of STAT3 by curcurbitacin-I (JSI-124) sensitized human B-leukemia cells to apoptosis.

  Molecular cancer therapeutics 20101201

• mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

  Molecular cell 20101124

• DDK phosphorylates checkpoint clamp component Rad9 and promotes its release from damaged chromatin.

  Molecular cell 20101124

• Lipopolysaccharide-induced activation of NF-κB non-canonical pathway requires BCL10 serine 138 and NIK phosphorylations.

  Experimental cell research 20101115

• CdSe/ZnS quantum dots based electrochemical immunoassay for the detection of phosphorylated bovine serum albumin.

  Biosensors & bioelectronics 20101115

• Crosstalk between mRNA 3' end processing and transcription initiation.

  Molecular cell 20101112

• Proline isomerase Pin1 represses terminal differentiation and myocyte enhancer factor 2C function in skeletal muscle cells.

  The Journal of biological chemistry 20101105

• Phosphorylated and nonphosphorylated serine and threonine residues evolve at different rates in mammals.

  Molecular biology and evolution 20101101

• The inhibitor of phagocytosis, O-phospho-L-serine, suppresses Müller glia proliferation and cone cell regeneration in the light-damaged zebrafish retina.

  Experimental eye research 20101101

• Different responses of tonoplast proton pumps in cucumber roots to cadmium and copper.

  Journal of plant physiology 20101101

• Heat shock modulates phosphorylation status and activity of nucleoside diphosphate kinase in cultured sugarcane cells.

  Plant cell reports 20101101

• Activation of Atg1 kinase in autophagy by regulated phosphorylation.

  Autophagy 20101101

• The functional interplay between protein kinase CK2 and CCA1 transcriptional activity is essential for clock temperature compensation in Arabidopsis.

  PLoS genetics 20101101

• p53-Dependent subcellular proteome localization following DNA damage.

  Proteomics 20101101

• Degree of immobilization of synthetic RGDS(PO(3)H(2))PA peptides on titanium surfaces.

  Dental materials journal 20101101

• Combination of sapacitabine and HDAC inhibitors stimulates cell death in AML and other tumour types.

  British journal of cancer 20101026

• Interdependent phosphorylation within the kinase domain T-loop Regulates CHK2 activity.

  The Journal of biological chemistry 20101022

• Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis.

  The Journal of biological chemistry 20101022

• Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells.

  The Journal of biological chemistry 20101022

• Determination of L-serine-O-phosphate in rat and mouse brain tissue using high-performance liquid chromatography and fluorimetric detection.

  Analytical biochemistry 20101015

• Contraction regulates site-specific phosphorylation of TBC1D1 in skeletal muscle.

  The Biochemical journal 20101015

• Discovery of small molecule inhibitors of the PH domain leucine-rich repeat protein phosphatase (PHLPP) by chemical and virtual screening.

  Journal of medicinal chemistry 20101014

• Role of ligand-dependent GR phosphorylation and half-life in determination of ligand-specific transcriptional activity.

  Molecular and cellular endocrinology 20101007

• Identification of a novel phosphorylation site in hepatitis C virus NS5A.

  The Journal of general virology 20101001

• Trypanosomatid protein phosphatases.

  Molecular and biochemical parasitology 20101001

• Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy.

  Diabetes 20101001

• Analysis of changes in tyrosine and serine phosphorylation of red cell membrane proteins induced by P. falciparum growth.

  Proteomics 20101001

• Uniform transitions of the general RNA polymerase II transcription complex.

  Nature structural & molecular biology 20101001

• Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.

  Nature structural & molecular biology 20101001

• Gene-specific RNA polymerase II phosphorylation and the CTD code.

  Nature structural & molecular biology 20101001

• The SR-BI partner PDZK1 facilitates hepatitis C virus entry.

  PLoS pathogens 20101001

• Transcriptional responses of Leptospira interrogans to host innate immunity: significant changes in metabolism, oxygen tolerance, and outer membrane.

  PLoS neglected tropical diseases 20101001

• Amphiregulin mediates estrogen, progesterone, and EGFR signaling in the normal rat mammary gland and in hormone-dependent rat mammary cancers.

  Hormones & cancer 20101001

• Cocaine- and amphetamine-regulated transcript (CART) peptide activates ERK pathways via NMDA receptors in rat spinal cord dorsal horn in an age-dependent manner.

  Regulatory peptides 20100924

• Kinetic analysis of 14-3-3-inhibited Arabidopsis thaliana nitrate reductase.

  Biochemistry 20100921

• Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.

  Nature 20100916

• 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.

  The Biochemical journal 20100915

• Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4.

  The EMBO journal 20100915

• Focus on histone variant H2AX: to be or not to be.

  FEBS letters 20100910

• ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4.

  Oncogene 20100909

• Physical and antibiotic stresses require activation of the RsbU phosphatase to induce the general stress response in Listeria monocytogenes.

  Microbiology (Reading, England) 20100901

• Prophossi: automating expert validation of phosphopeptide-spectrum matches from tandem mass spectrometry.

  Bioinformatics (Oxford, England) 20100901

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  Molecular cancer research : MCR 20100601

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  Cell 20100430

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  The Plant journal : for cell and molecular biology 20100401

• Screening kinase inhibitors with a microarray-based fluorescent and resonance light scattering assay.

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  Current biology : CB 20100323

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  Developmental cell 20100316

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  Journal of biomedical materials research. Part A 20100315

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  Cell cycle (Georgetown, Tex.) 20100315

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  American journal of respiratory cell and molecular biology 20100301

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  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100301

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  Molecular genetics and metabolism 20100301

• Short-term stimulation of the thiazide-sensitive Na+-Cl- cotransporter by vasopressin involves phosphorylation and membrane translocation.

  American journal of physiology. Renal physiology 20100301

• ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.

  Carcinogenesis 20100301

• Interleukin-1 Receptor-Associated Kinase-1 (IRAK-1) functionally associates with PKCepsilon and VASP in the regulation of macrophage migration.

  Molecular immunology 20100301

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  Biochimica et biophysica acta 20100301

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• Is there a better time of day to have a heart attack?

  Circulation research 20100219

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  Neurobiology of aging 20100201

• Shape and evolution of thermostable protein structure.

  Proteins 20100201

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  Apoptosis : an international journal on programmed cell death 20100201

• Protein tyrosine phosphatases in glioma biology.

  Acta neuropathologica 20100201

• Glucuronic acid and phosphoserine act as mineralization mediators of collagen I based biomimetic substrates.

  Journal of materials science. Materials in medicine 20100201

• Regulation of heat shock protein 60 and 72 expression in the failing heart.

  Journal of molecular and cellular cardiology 20100201

• GGA autoinhibition revisited.

  Traffic (Copenhagen, Denmark) 20100201

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  Annals of oncology : official journal of the European Society for Medical Oncology 20100201

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  British journal of cancer 20100119

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  Journal of cell science 20100115

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  Biology of the cell 20100113

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  Cardiovascular research 20100101

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  The Journal of general virology 20100101

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  Cellular signalling 20100101

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  International journal of Alzheimer's disease 20100101

• Phosphoproteomics profiling of human skin fibroblast cells reveals pathways and proteins affected by low doses of ionizing radiation.

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• Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition.

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• Focus on phosphoarginine and phospholysine.

  Current protein & peptide science 20091201

• Time-resolved observation of product ions generated by 157 nm photodissociation of singly protonated phosphopeptides.

  Journal of the American Society for Mass Spectrometry 20091201

• Therapeutic effects of anticoagulant agents on preeclampsia in a murine model induced by phosphatidylserine/phosphatidylcholine microvesicles.

  Placenta 20091201

• Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis.

  Nature cell biology 20091201

• Ultraviolet photodissociation at 266 nm of phosphorylated peptide cations.

  Rapid communications in mass spectrometry : RCM 20091201

• Urgent termination of pregnancy in pre-eclampsia and panel of antiphospholipid antibodies.

  American journal of reproductive immunology (New York, N.Y. : 1989) 20091201

• CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer.

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  Marine drugs 20091201

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• Analysis of phosphorylated peptides by double pseudoneutral loss extraction coupled with derivatization using N-(4-bromobenzoyl)aminoethanethiol.

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• Phosphorylation at S384 regulates the activity of the TaALMT1 malate transporter that underlies aluminum resistance in wheat.

  The Plant journal : for cell and molecular biology 20091101

• Differential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signaling.

  Molecular & cellular proteomics : MCP 20091101

• Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability.

  American journal of physiology. Lung cellular and molecular physiology 20091101

• Atf4 regulates obesity, glucose homeostasis, and energy expenditure.

  Diabetes 20091101

• The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats.

  The international journal of biochemistry & cell biology 20091101

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  Autophagy 20091101

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  The Indian journal of radiology & imaging 20091101

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  PLoS computational biology 20091101

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  Molecular cell 20091023

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• Developmental switch in NF-kappaB signalling required for neurite growth.

  Development (Cambridge, England) 20091015

• Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation.

  The Journal of biological chemistry 20091009

• Controlling peptide folding with repulsive interactions between phosphorylated amino acids and tryptophan.

  Journal of the American Chemical Society 20091007

• Protein phosphorylation influences proteolytic cleavage and kinase substrate properties exemplified by analysis of in vitro phosphorylated Plasmodium falciparum glideosome-associated protein 45 by nano-ultra performance liquid chromatography-tandem mass spectrometry.

  Analytical biochemistry 20091001

• Enhancing the apoptotic potential of insulin-like growth factor-binding protein-3 in prostate cancer by modulation of CK2 phosphorylation.

  Molecular endocrinology (Baltimore, Md.) 20091001

• Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1.

  Diabetes 20091001

• The trafficking/interaction of eNOS and caveolin-1 induced by insulin modulates endothelial nitric oxide production.

  Molecular endocrinology (Baltimore, Md.) 20091001

• DNA damage response induced by tobacco smoke in normal human bronchial epithelial and A549 pulmonary adenocarcinoma cells assessed by laser scanning cytometry.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20091001

• The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat.

  Behavioural pharmacology 20091001

• Quantitative analysis of the human spindle phosphoproteome at distinct mitotic stages.

  Journal of proteome research 20091001

• Involvement of protein kinase C and Src tyrosine kinase in acute tolerance to ethanol inhibition of spinal NMDA-induced pressor responses in rats.

  British journal of pharmacology 20091001

• Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion.

  Molecular cancer therapeutics 20091001

• The alpha,alpha-difluorinated phosphonate L-pSer-analogue: an accessible chemical tool for studying kinase-dependent signal transduction.

  Chemistry & biology 20090925

• Journal club. A biologist is gratified to find reconciliation for a conflicted receptor.

  Nature 20090910

• Detection and analysis of protein histidine phosphorylation.

  Molecular and cellular biochemistry 20090901

• The phosphorylation status of membrane-bound nucleoside diphosphate kinase in epithelia and the role of AMP.

  Molecular and cellular biochemistry 20090901

• Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.

  Molecular and cellular biochemistry 20090901

• CDK11p58 phosphorylation of PAK1 Ser174 promotes DLC2 binding and roles on cell cycle progression.

  Journal of biochemistry 20090901

• Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

  Molecular & cellular proteomics : MCP 20090901

• Cloning and characterization of two novel chloroplastic glycerol-3-phosphate dehydrogenases from Dunaliella viridis.

  Plant molecular biology 20090901

• Modification of phosphatidylserine by hypochlorous acid.

  Chemistry and physics of lipids 20090901

• SADB phosphorylation of gamma-tubulin regulates centrosome duplication.

  Nature cell biology 20090901

• Recognition of an intra-chain tandem 14-3-3 binding site within PKCepsilon.

  EMBO reports 20090901

• SAD kinase keeps centrosomes lonely.

  Nature cell biology 20090901

• Trehalose metabolism: from osmoprotection to signaling.

  International journal of molecular sciences 20090901

• Synthesis of diazo functionalized solid supports and their application towards the enrichment of phosphorylated peptides.

  Organic & biomolecular chemistry 20090821

• Phosphorylation of CLASP2 by GSK-3beta regulates its interaction with IQGAP1, EB1 and microtubules.

  Journal of cell science 20090815

• Parathyroid hormone suppresses insulin signaling in adipocytes.

  Molecular and cellular endocrinology 20090813

• Determination of AMP-activated protein kinase phosphorylation sites in recombinant protein expressed using the pET28a vector: a cautionary tale.

  Protein expression and purification 20090801

• Morphine induces DNA damage and P53 activation in CD3+ T cells.

  Biochimica et biophysica acta 20090801

• Systems-wide analysis of a phosphatase knock-down by quantitative proteomics and phosphoproteomics.

  Molecular & cellular proteomics : MCP 20090801

• Activation of group III metabotropic glutamate receptor reduces intracellular calcium in beta-amyloid peptide [31-35]-treated cortical neurons.

  Neurotoxicity research 20090801

• Caenorhabditis elegans has a phosphoproteome atypical for metazoans that is enriched in developmental and sex determination proteins.

  Journal of proteome research 20090801

• Activation of mTORC1 signaling pathway in AIDS-related lymphomas.

  The American journal of pathology 20090801

• Hierarchical modeling of activation mechanisms in the ABL and EGFR kinase domains: thermodynamic and mechanistic catalysts of kinase activation by cancer mutations.

  PLoS computational biology 20090801

• Occludin phosphorylation and ubiquitination regulate tight junction trafficking and vascular endothelial growth factor-induced permeability.

  The Journal of biological chemistry 20090731

• Protein kinase C isoforms differentially phosphorylate Ca(v)1.2 alpha(1c).

  Biochemistry 20090721

• The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.

  Science (New York, N.Y.) 20090717

• EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt.

  Cancer cell 20090707

• The phosphoproteome of bloodstream form Trypanosoma brucei, causative agent of African sleeping sickness.

  Molecular & cellular proteomics : MCP 20090701

• Purple acid phosphatase-like sequences in prokaryotic genomes and the characterization of an atypical purple alkaline phosphatase from Burkholderia cenocepacia J2315.

  Gene 20090701

• IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation.

  American journal of physiology. Lung cellular and molecular physiology 20090701

• Setaria cervi dual specific phosphatase: characterization and its effect on eosinophil degranulation.

  Parasitology 20090701

• Phosphoproteomic analysis of the human pathogen Trypanosoma cruzi at the epimastigote stage.

  Proteomics 20090701

• KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.

  Blood 20090625

• Role of SUMO in RNF4-mediated promyelocytic leukemia protein (PML) degradation: sumoylation of PML and phospho-switch control of its SUMO binding domain dissected in living cells.

  The Journal of biological chemistry 20090612

• Opposite effects of PDGF-BB and prostaglandin E1 on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins.

  Experimental cell research 20090610

• mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3.

  Experimental cell research 20090610

• Reaction cycle of Thermotoga maritima copper ATPase and conformational characterization of catalytically deficient mutants.

  Biochemistry 20090609

• Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin.

  The Journal of biological chemistry 20090605

• PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice.

  Cerebellum (London, England) 20090601

• Cyclic GMP specifically suppresses Type-Ialpha cGMP-dependent protein kinase expression by ubiquitination.

  Cellular signalling 20090601

• TLR4/MyD88/PI3K interactions regulate TLR4 signaling.

  Journal of leukocyte biology 20090601

• Discovery and identification of serine and threonine phosphorylated proteins in activated mast cells: implications for regulation of protein synthesis in the rat basophilic leukemia mast cell line RBL-2H3.

  Journal of proteome research 20090601

• Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

  Human mutation 20090601

• NFATc2 Ser170 phosphorylation marks mitosis in development and ES cells.

  Cell cycle (Georgetown, Tex.) 20090601

• Immunohistochemical localization of phosphohistidine phosphatase PHPT1 in mouse and human tissues.

  Upsala journal of medical sciences 20090601

• Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A/C.

  The FEBS journal 20090601

• A sensitive magnetic bead method for the detection and identification of tyrosine phosphorylation in proteins by MALDI-TOF/TOF MS.

  Proteomics 20090601

• PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts.

  Developmental cell 20090601

• p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.

  The Journal of biological chemistry 20090529

• Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR.

  The Journal of biological chemistry 20090529

• Structure and in vivo requirement of the yeast Spt6 SH2 domain.

  Journal of molecular biology 20090529

• Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK.

  The Journal of biological chemistry 20090522

• Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation.

  The Journal of biological chemistry 20090522

• Activation-induced degradation of FLIP(L) is mediated via the phosphatidylinositol 3-kinase/Akt signaling pathway in macrophages.

  The Journal of biological chemistry 20090522

• CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

  Nature 20090521

• Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

  Molecular & cellular proteomics : MCP 20090501

• In silico analysis of phosphoproteome data suggests a rich-get-richer process of phosphosite accumulation over evolution.

  Molecular & cellular proteomics : MCP 20090501

• 14-3-3:Shc scaffolds integrate phosphoserine and phosphotyrosine signaling to regulate phosphatidylinositol 3-kinase activation and cell survival.

  The Journal of biological chemistry 20090501

• Phosphoserine and specific types of its coordination in copper(II) and adenosine nucleotides systems - Potentiometric and spectroscopic studies.

  Journal of inorganic biochemistry 20090501

• Functional involvement of protein kinase C-betaII and its substrate, myristoylated alanine-rich C-kinase substrate (MARCKS), in insulin-stimulated glucose transport in L6 rat skeletal muscle cells.

  Diabetologia 20090501

• Occurrence of phosphatidyl-D-serine in the rat cerebrum.

  Biochemical and biophysical research communications 20090501

• Identification of casein kinase-1 phosphorylation sites on TDP-43.

  Biochemical and biophysical research communications 20090501

• Phosphorylated serine and threonine residues promote site-specific fragmentation of singly charged, arginine-containing peptide ions.

  Rapid communications in mass spectrometry : RCM 20090501

• Oncostatin M-induced CCL2 transcription in osteoblastic cells is mediated by multiple levels of STAT-1 and STAT-3 signaling: an implication for the pathogenesis of arthritis.

  Arthritis and rheumatism 20090501

• RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways.

  Proteomics 20090501

• Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity.

  PLoS pathogens 20090501

• Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease.

  PLoS medicine 20090501

• Natural killer T cells activated by a lipopeptidophosphoglycan from Entamoeba histolytica are critically important to control amebic liver abscess.

  PLoS pathogens 20090501

• EBAG9 inducing hyporesponsiveness of T cells promotes tumor growth and metastasis in 4T1 murine mammary carcinoma.

  Cancer science 20090501

• Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.

  PLoS biology 20090501

• Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells.

  PLoS biology 20090501

• Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.

  PLoS pathogens 20090501

• Galpha(q)-mediated plasma membrane translocation of sphingosine kinase-1 and cross-activation of S1P receptors.

  Biochimica et biophysica acta 20090501

• Probing the mechanism of electron capture and electron transfer dissociation using tags with variable electron affinity.

  Journal of the American Chemical Society 20090422

• Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis.

  The Journal of biological chemistry 20090403

• Depletion of the poly(C)-binding proteins alphaCP1 and alphaCP2 from K562 cells leads to p53-independent induction of cyclin-dependent kinase inhibitor (CDKN1A) and G1 arrest.

  The Journal of biological chemistry 20090403

• A scalable synthesis of the IP7 isomer, 5-PP-Ins(1,2,3,4,6)P5.

  Organic letters 20090402

• Ran GTPase guanine nucleotide exchange factor RCC1 is phosphorylated on serine 11 by cdc2 kinase in vitro.

  Molecular biology reports 20090401

• Identification and characterization of neuronal mitogen-activated protein kinase substrates using a specific phosphomotif antibody.

  Molecular & cellular proteomics : MCP 20090401

• Sulfonation and phosphorylation of regions of the dioxin receptor susceptible to methionine modifications.

  Molecular & cellular proteomics : MCP 20090401

• Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB.

  Nature cell biology 20090401

• Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.

  Nature cell biology 20090401

• Distinct role of PLCbeta3 in VEGF-mediated directional migration and vascular sprouting.

  Journal of cell science 20090401

• Skp2: caught in the Akt.

  Nature cell biology 20090401

• Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signaling.

  PLoS computational biology 20090401

• Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells.

  Developmental cell 20090401

• The arrestin fold: variations on a theme.

  Current genomics 20090401

• Non-specific in vivo inhibition of CK1 by the pyridinyl imidazole p38 inhibitors SB 203580 and SB 202190.

  BMB reports 20090331

• [Preparation and preliminary application of rabbit polyclonal antibodies against intracellular peptides of human platelet glycoprotein GPIbalpha].

  Zhonghua yi xue za zhi 20090331

• Role of p53 in mitochondrial biogenesis and apoptosis in skeletal muscle.

  Physiological genomics 20090303

• Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites.

  Molecular & cellular proteomics : MCP 20090301

• Epitope characterization of a supramolecular protein assembly with a collection of monoclonal antibodies: the case of casein micelle.

  Molecular immunology 20090301

• Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells.

  Cardiovascular research 20090301

• TTP at Ser245 phosphorylation by AKT is required for binding to 14-3-3.

  Journal of biochemistry 20090301

• [Development of a functional cell-based HTS assay for the identification mGluR4 modulators].

  Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090301

• Phosphorylation of the consensus sites of protein kinase A on alpha1D L-type calcium channel.

  The Journal of biological chemistry 20090220

• Prognostic significance of 14-3-3sigma expression in oral squamous cell carcinoma (OSCC).

  Oral oncology 20090201

• Surface-grafting of phosphates onto a polymer for potential biomimetic functionalization of biomaterials.

  Journal of colloid and interface science 20090201

• Mhp493 (P216) is a proteolytically processed, cilium and heparin binding protein of Mycoplasma hyopneumoniae.

  Molecular microbiology 20090201

• Obligatory role for phosphatidylinositol 4,5-bisphosphate in activation of native TRPC1 store-operated channels in vascular myocytes.

  The Journal of physiology 20090201

• Where Wnts went: the exploding field of Lrp5 and Lrp6 signaling in bone.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201

• In silico evidence for functional specialization after genome duplication in yeast.

  FEMS yeast research 20090201

• The effect of post-translational and process-induced modifications on the multistage gas-phase fragmentation reactions of protonated peptides.

  Combinatorial chemistry & high throughput screening 20090201

• An antiviral response directed by PKR phosphorylation of the RNA helicase A.

  PLoS pathogens 20090201

• Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2.

  The Journal of biological chemistry 20090123

• Protein kinase D1 autophosphorylation via distinct mechanisms at Ser744/Ser748 and Ser916.

  The Journal of biological chemistry 20090123

• Protein kinase C theta (PKCtheta)-dependent phosphorylation of PDK1 at Ser504 and Ser532 contributes to palmitate-induced insulin resistance.

  The Journal of biological chemistry 20090123

• Inhibition of lactoperoxidase by its own catalytic product: crystal structure of the hypothiocyanate-inhibited bovine lactoperoxidase at 2.3-A resolution.

  Biophysical journal 20090121

• Cell cycle regulation of the BRCA1/acetyl-CoA-carboxylase complex.

  Biochemical and biophysical research communications 20090116

• Celebesides A-C and theopapuamides B-D, depsipeptides from an Indonesian sponge that inhibit HIV-1 entry.

  The Journal of organic chemistry 20090116

• Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression.

  Molecular cell 20090116

• Clinical and pathological characteristics of patients with leucine-rich repeat kinase-2 mutations.

  Movement disorders : official journal of the Movement Disorder Society 20090115

• The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms.

  Experimental cell research 20090115

• The stability and transactivation potential of the mammalian MafA transcription factor are regulated by serine 65 phosphorylation.

  The Journal of biological chemistry 20090109

• Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells.

  Circulation research 20090102

• Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs.

  Circulation research 20090102

• ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding.

  Investigative ophthalmology & visual science 20090101

• Tissue-specific difference in the molecular mechanisms for the development of acute insulin resistance after injury.

  Endocrinology 20090101

• Giardia lamblia: Characterization of ecto-phosphatase activities.

  Experimental parasitology 20090101

• Identification of PP2A as a novel interactor and regulator of TRIP-Br1.

  Cellular signalling 20090101

• PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.

  Experimental cell research 20090101

• Direct analysis of liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS).

  Journal of the American Society for Mass Spectrometry 20090101

• Restoring wtp53 activity in HIPK2 depleted MCF7 cells by modulating metallothionein and zinc.

  Experimental cell research 20090101

• Detection and assignment of phosphoserine and phosphothreonine residues by (13)C- (31)P spin-echo difference NMR spectroscopy.

  Journal of biomolecular NMR 20090101

• WAVE2 is regulated by multiple phosphorylation events within its VCA domain.

  Cell motility and the cytoskeleton 20090101

• Norrin attenuates protease-mediated death of transformed retinal ganglion cells.

  Molecular vision 20090101

• PP2A regulates ionizing radiation-induced apoptosis through Ser46 phosphorylation of p53.

  Molecular cancer therapeutics 20090101

• Microarray and cDNA sequence analysis of transcription during nerve-dependent limb regeneration.

  BMC biology 20090101

• High correlation of the proteome patterns in bone marrow and peripheral blood blast cells in patients with acute myeloid leukemia.

  Journal of translational medicine 20090101

• Transient dynamic actin cytoskeletal change stimulates the osteoblastic differentiation.

  Journal of bone and mineral metabolism 20090101

• Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

  PloS one 20090101

• ARC (NSC 188491) has identical activity to Sangivamycin (NSC 65346) including inhibition of both P-TEFb and PKC.

  BMC cancer 20090101

• Systematic functional analysis of Bicaudal-D serine phosphorylation and intragenic suppression of a female sterile allele of BicD.

  PloS one 20090101

• The analysis of phosphoproteomes by selective labelling and advanced mass spectrometric techniques.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Chemical tagging strategies for mass spectrometry-based phospho-proteomics.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts.

  PloS one 20090101

• HAC stability in murine cells is influenced by nuclear localization and chromatin organization.

  BMC cell biology 20090101

• Ser/Thr/Tyr protein phosphorylation in the archaeon Halobacterium salinarum--a representative of the third domain of life.

  PloS one 20090101

• Early cellular signaling responses to axonal injury.

  Cell communication and signaling : CCS 20090101

• Solution structure of the parvulin-type PPIase domain of Staphylococcus aureus PrsA--implications for the catalytic mechanism of parvulins.

  BMC structural biology 20090101

• Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction.

  BMC systems biology 20090101

• BMP-2 signaling in ovarian cancer and its association with poor prognosis.

  Journal of ovarian research 20090101

• Detection of histone H3 phosphorylation in cultured cells and tissue sections by immunostaining.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Interaction of hookworm 14-3-3 with the forkhead transcription factor DAF-16 requires intact Akt phosphorylation sites.

  Parasites & vectors 20090101

• Regulation of dopamine transporter activity by carboxypeptidase E.

  Molecular brain 20090101

• Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins.

  Methods in enzymology 20090101

• Revised Mimivirus major capsid protein sequence reveals intron-containing gene structure and extra domain.

  BMC molecular biology 20090101

• Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.

  Molecular cancer 20090101

• Avicin D: a protein reactive plant isoprenoid dephosphorylates Stat 3 by regulating both kinase and phosphatase activities.

  PloS one 20090101

• Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytes.

  Arthritis research & therapy 20090101

• Pacing-induced cardiac gap junction remodeling: modulation of connexin43 phosphorylation state.

  American journal of therapeutics 20090101

• The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens.

  BMC microbiology 20090101

• Genomic characterization of methanomicrobiales reveals three classes of methanogens.

  PloS one 20090101

• Nicotine-reduced endothelial progenitor cell senescence through augmentation of telomerase activity via the PI3K/Akt pathway.

  Cytotherapy 20090101

• Fluorine-18 labeling of phosphopeptides: a potential approach for the evaluation of phosphopeptide metabolism in vivo.

  Biopolymers 20090101

• Expression and function of the insulin receptor substrate proteins in cancer.

  Cell communication and signaling : CCS 20090101

• Identification of non-muscle myosin heavy chain as a substrate for Cdk5 and tool for drug screening.

  Journal of biomedical science 20090101

• Multiple horizontal gene transfer events and domain fusions have created novel regulatory and metabolic networks in the oomycete genome.

  PloS one 20090101

• A systematic investigation of the protein kinases involved in NMDA receptor-dependent LTD: evidence for a role of GSK-3 but not other serine/threonine kinases.

  Molecular brain 20090101

• Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

  BMC cell biology 20090101

• Protein phosphorylation by semisynthesis: from paper to practice.

  Methods in enzymology 20090101

• 14-3-3sigma gene silencing during melanoma progression and its role in cell cycle control and cellular senescence.

  Molecular cancer 20090101

• Glutamatergic neurotransmission in the first retinal synapse mediated by metabotropic receptors--electroretinographic study.

  Folia medica 20090101

• The direct effect of focal adhesion kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis.

  BMC cancer 20090101

• Glucocorticoid evoked upregulation of RCAN1-1 in human leukemic CEM cells susceptible to apoptosis.

  Journal of molecular signaling 20090101

• A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling.

  PloS one 20090101

• Function, regulation and pathological roles of the Gab/DOS docking proteins.

  Cell communication and signaling : CCS 20090101

• The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu.

  Retrovirology 20090101

• Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.

  Genome biology 20090101

• Chronic NMDA administration to rats increases brain pro-apoptotic factors while decreasing anti-Apoptotic factors and causes cell death.

  BMC neuroscience 20090101

• 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

  PloS one 20090101

• Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network.

  PloS one 20090101

• The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline.

  PloS one 20090101

• Point mutations in GLI3 lead to misregulation of its subcellular localization.

  PloS one 20090101

• ADP ribosylation factor like 2 (Arl2) regulates breast tumor aggressivity in immunodeficient mice.

  PloS one 20090101

• Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease.

  Molecular brain 20090101

• PD 0332991, a selective cyclin D kinase 4/6 inhibitor, preferentially inhibits proliferation of luminal estrogen receptor-positive human breast cancer cell lines in vitro.

  Breast cancer research : BCR 20090101

• Etiopathogenesis of benign prostatic hypeprlasia.

  Indian journal of urology : IJU : journal of the Urological Society of India 20090101

• A concerted kinase interplay identifies PPARgamma as a molecular target of ghrelin signaling in macrophages.

  PloS one 20090101

• Phosphorylation regulates human T-cell leukemia virus type 1 Rex function.

  Retrovirology 20090101

• ERalpha increases expression and interacts with TERT in cataractous canine lens epithelial cells.

  Molecular vision 20090101

• Akt and SHIP modulate Francisella escape from the phagosome and induction of the Fas-mediated death pathway.

  PloS one 20090101

• Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase.

  PloS one 20090101

• Kinetic characterization and phosphoregulation of the Francisella tularensis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).

  PloS one 20090101

• Influence of sex on gene expression in human corneal epithelial cells.

  Molecular vision 20090101

• The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function.

  PloS one 20090101

• The SARS Coronavirus 3a protein causes endoplasmic reticulum stress and induces ligand-independent downregulation of the type 1 interferon receptor.

  PloS one 20090101

• Usefulness of GPT for diagnosis of metabolic syndrome in obese Japanese children.

  Journal of atherosclerosis and thrombosis 20090101

• Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors.

  PloS one 20090101

• Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation.

  PloS one 20090101

• Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.

  Molecular cancer 20090101

• Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

  BMC biochemistry 20090101

• Evolution and origin of HRS, a protein interacting with Merlin, the Neurofibromatosis 2 gene product.

  Gene regulation and systems biology 20090101

• Application of mass spectrometry-based proteomics for biomarker discovery in neurological disorders.

  Annals of Indian Academy of Neurology 20090101

• Structure and function of the phosphothreonine-specific FHA domain.

  Science signaling 20081223

• Evaluation of gas-phase rearrangement and competing fragmentation reactions on protein phosphorylation site assignment using collision induced dissociation-MS/MS and MS3.

  Analytical chemistry 20081215

• Induction of serum- and glucocorticoid-induced kinase-1 (SGK1) by cAMP regulates increases in alpha-ENaC.

  Journal of cellular physiology 20081201

• Activation loop phosphorylation of the atypical MAP kinases ERK3 and ERK4 is required for binding, activation and cytoplasmic relocalization of MK5.

  Journal of cellular physiology 20081201

• BMP-2 increases migration of human chondrosarcoma cells via PI3K/Akt pathway.

  Journal of cellular physiology 20081201

• DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death.

  Cell death and differentiation 20081201

• Titanium foam-bioactive nanofiber hybrids for bone regeneration.

  Journal of tissue engineering and regenerative medicine 20081201

• Estrogen receptor alpha (ERalpha) phospho-serine-118 is highly expressed in human uterine leiomyomas compared to matched myometrium.

  Virchows Archiv : an international journal of pathology 20081201

• Phosphorylation of the Saccharomyces cerevisiae Grx4p glutaredoxin by the Bud32p kinase unveils a novel signaling pathway involving Sch9p, a yeast member of the Akt / PKB subfamily.

  The FEBS journal 20081201

• The IQGAP Iqg1 is a regulatory target of CDK for cytokinesis in Candida albicans.

  The EMBO journal 20081119

• Magnetic electrochemical immunoassays with quantum dot labels for detection of phosphorylated acetylcholinesterase in plasma.

  Analytical chemistry 20081115

• Characterization of Ser338 phosphorylation for Raf-1 activation.

  The Journal of biological chemistry 20081114

• Cysteine synthase (CysM) of Mycobacterium tuberculosis is an O-phosphoserine sulfhydrylase: evidence for an alternative cysteine biosynthesis pathway in mycobacteria.

  The Journal of biological chemistry 20081114

• Integrin cross-talk in endothelial cells is regulated by protein kinase A and protein phosphatase 1.

  The Journal of biological chemistry 20081114

• Ryanodine receptor phosphorylation at Serine 2030, 2808 and 2814 in rat cardiomyocytes.

  Biochemical and biophysical research communications 20081107

• Phosphorylation of Plk1 at Ser326 regulates its functions during mitotic progression.

  Oncogene 20081106

• The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.

  Biochemistry 20081104

• O-phospho-L-serine and the thiocarboxylated sulfur carrier protein CysO-COSH are substrates for CysM, a cysteine synthase from Mycobacterium tuberculosis.

  Biochemistry 20081104

• Protein kinase Cdelta expression in breast cancer as measured by real-time PCR, western blotting and ELISA.

  British journal of cancer 20081104

• Extracellular alkaline phosphatase is a sensitive marker for cellular stimulation and exocytosis in heterotroph cell cultures of Chenopodium rubrum.

  Journal of plant physiology 20081101

• Mass spectrometry analysis of oxidized phospholipids.

  Chemistry and physics of lipids 20081101

• JNK regulates cell migration through promotion of tyrosine phosphorylation of paxillin.

  Cellular signalling 20081101

• Preservation of cGMP-induced relaxation of pulmonary veins of fetal lambs exposed to chronic high altitude hypoxia: role of PKG and Rho kinase.

  American journal of physiology. Lung cellular and molecular physiology 20081101

• The RACK1 signal anchor protein from Trypanosoma brucei associates with eukaryotic elongation factor 1A: a role for translational control in cytokinesis.

  Molecular microbiology 20081101

• Three-dimensional neuroblastoma cell culture: proteomic analysis between monolayer and multicellular tumor spheroids.

  Pediatric surgery international 20081101

• Hyaluronan-mediated leukocyte adhesion and dextran sulfate sodium-induced colitis are attenuated in the absence of signal transducer and activator of transcription 1.

  The American journal of pathology 20081101

• MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation.

  Development (Cambridge, England) 20081101

• Suppressor of cytokine signaling-3 (SOCS-3) and a deficit of serine/threonine (Ser/Thr) phosphoproteins involved in leptin transduction mediate the effect of fructose on rat liver lipid metabolism.

  Hepatology (Baltimore, Md.) 20081101

• DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus.

  Journal of radiation research 20081101

• Root proteomic responses to heat stress in two Agrostis grass species contrasting in heat tolerance.

  Journal of experimental botany 20081101

• P53 transcription-independent activity mediates selenite-induced acute promyelocytic leukemia NB4 cell apoptosis.

  BMB reports 20081031

• Temperature sensitivity of phospho-Ser(473)-PKB/AKT.

  Biochemical and biophysical research communications 20081024

• Regulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neurons.

  The Journal of biological chemistry 20081024

• Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells.

  Chemico-biological interactions 20081022

• Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.

  Bioorganic & medicinal chemistry letters 20081015

• CDK targets Sae2 to control DNA-end resection and homologous recombination.

  Nature 20081002

• Emerging roles for protein histidine phosphorylation in cellular signal transduction: lessons from the islet beta-cell.

  Journal of cellular and molecular medicine 20081001

• Unraveling molecular complexity of phosphorylated human cardiac troponin I by top down electron capture dissociation/electron transfer dissociation mass spectrometry.

  Molecular & cellular proteomics : MCP 20081001

• WNK2 modulates MEK1 activity through the Rho GTPase pathway.

  Cellular signalling 20081001

• Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites.

  Cellular signalling 20081001

• Cdk5 phosphorylates PLD2 to mediate EGF-dependent insulin secretion.

  Cellular signalling 20081001

• DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks.

  DNA repair 20081001

• The role of phosphorylated residues in peptide-peptide noncovalent complexes formation.

  Journal of the American Society for Mass Spectrometry 20081001

• Effect of cryopreservation on phosphorylation state of proteins involved in sperm motility initiation in sea bream.

  Cryobiology 20081001

• PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint.

  EMBO reports 20081001

• Cyclophosphoramidate ion as mass defect marker for efficient detection of protein serine phosphorylation.

  Analytical chemistry 20081001

• Co-ordinated expression of amino acid metabolism in response to N and S deficiency during wheat grain filling.

  Journal of experimental botany 20081001

• O-phospho-L-serine: a modulator of bone healing in calcium-phosphate cements.

  Biomedizinische Technik. Biomedical engineering 20081001

• Microfluidic patterning of nanodisc lipid bilayers and multiplexed analysis of protein interaction.

  Lab on a chip 20081001

• Solid-state NMR spectroscopy using the lost I spin magnetization in polarization transfer experiments.

  Solid state nuclear magnetic resonance 20081001

• Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.

  Molecular cancer therapeutics 20081001

• Inhibition of methylation and changes in gene expression in relation to neural tube defects.

  Birth defects research. Part A, Clinical and molecular teratology 20081001

• [The preparation of bioglass/collagen/phosphoserine biomemetic composite scaffold and a study on its cytocompatibility].

  Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20081001

• Crystal structure of a sulfur carrier protein complex found in the cysteine biosynthetic pathway of Mycobacterium tuberculosis.

  Biochemistry 20080930

• Identification and characterization of a general nuclear translocation signal in signaling proteins.

  Molecular cell 20080926

• Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover.

  Molecular cell 20080926

• CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation.

  Molecular cell 20080926

• Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37.

  Molecular cell 20080926

• A collaborative endeavor to design cholinesterase-based catalytic scavengers against toxic organophosphorus esters.

  Chemico-biological interactions 20080925

• RIM1alpha phosphorylation at serine-413 by protein kinase A is not required for presynaptic long-term plasticity or learning.

  Proceedings of the National Academy of Sciences of the United States of America 20080923

• ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage.

  Cell cycle (Georgetown, Tex.) 20080915

• p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.

  Journal of cellular biochemistry 20080901

• Phosphorylation and kinetics of mammalian cytochrome c oxidase.

  Molecular & cellular proteomics : MCP 20080901

• Evaluating CK2 activity with the antibody specific for the CK2-phosphorylated form of a kinase-targeting cochaperone Cdc37.

  Molecular and cellular biochemistry 20080901

• Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.

  Molecular pharmacology 20080901

• Immunohistochemical assessment of protein phosphorylation state: the dream and the reality.

  Histochemistry and cell biology 20080901

• RNA polymerase II-mediated transcription at active loci does not require histone H3S10 phosphorylation in Drosophila.

  Development (Cambridge, England) 20080901

• Involvement of the p53 and p73 transcription factors in neuroAIDS.

  Cell cycle (Georgetown, Tex.) 20080901

• Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.

  FEBS letters 20080820

• Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells.

  Journal of cellular biochemistry 20080815

• Intermediate phosphorylation reactions in the mechanism of ATP utilization by the copper ATPase (CopA) of Thermotoga maritima.

  The Journal of biological chemistry 20080815

• Array-based fluorescence assay for serine/threonine kinases using specific chemical reaction.

  Bioorganic & medicinal chemistry 20080815

• Redundant synthesis of cysteinyl-tRNACys in Methanosarcina mazei.

  The Journal of biological chemistry 20080808

• The homotetrameric phosphoseryl-tRNA synthetase from Methanosarcina mazei exhibits half-of-the-sites activity.

  The Journal of biological chemistry 20080808

• The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response.

  The EMBO journal 20080806

• A combinatorial H4 tail library for exploring the histone code.

  Biochemistry 20080805

• TGF-beta inhibits prolactin-induced expression of beta-casein by a Smad3-dependent mechanism.

  Journal of cellular biochemistry 20080801

• Importance of autophosphorylation at Ser186 in the A-loop of salt inducible kinase 1 for its sustained kinase activity.

  Journal of cellular biochemistry 20080801

• The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium.

  Cell death and differentiation 20080801

• Glucocorticoid receptor phosphorylation differentially affects target gene expression.

  Molecular endocrinology (Baltimore, Md.) 20080801

• Phosphoserine aminoacylation of tRNA bearing an unnatural base anticodon.

  Biochemical and biophysical research communications 20080801

• The Arabidopsis thaliana carboxyl-terminal domain phosphatase-like 2 regulates plant growth, stress and auxin responses.

  Plant molecular biology 20080801

• TiO(2)-based phosphoproteomic analysis of the plasma membrane and the effects of phosphatase inhibitor treatment.

  Journal of proteome research 20080801

• A Mg(2+)-dependent ecto-phosphatase activity on the external surface of Trypanosoma rangeli modulated by exogenous inorganic phosphate.

  Acta tropica 20080801

• GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis.

  Journal of experimental botany 20080801

• The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry.

  PLoS biology 20080801

• Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.

  The EMBO journal 20080723

• Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8.

  The Journal of biological chemistry 20080718

• Reactive nitrogen species is required for the activation of the AMP-activated protein kinase by statin in vivo.

  The Journal of biological chemistry 20080718

• Polymerized collagen inhibits fibroblast proliferation via a mechanism involving the formation of a beta1 integrin-protein phosphatase 2A-tuberous sclerosis complex 2 complex that suppresses S6K1 activity.

  The Journal of biological chemistry 20080718

• Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells.

  Journal of cell science 20080715

• A wide-ranging cellular response to UV damage of DNA.

  Cell cycle (Georgetown, Tex.) 20080715

• Context-dependent fluorescence detection of a phosphorylated tyrosine residue by a ribonucleopeptide.

  Journal of the American Chemical Society 20080709

• Phosphorylation of protein phosphatase 2Czeta by c-Jun NH2-terminal kinase at Ser92 attenuates its phosphatase activity.

  Biochemistry 20080708

• COUP-TFI modulates estrogen signaling and influences proliferation, survival and migration of breast cancer cells.

  Breast cancer research and treatment 20080701

• The cell cycle control protein cdc25C is present, and phosphorylated on serine 214 in the transition from germinal vesicle to metaphase II in human oocyte meiosis.

  Molecular reproduction and development 20080701

• Structural consequences of phosphorylation of two serine residues in the cytoplasmic domain of HIV-1 VpU.

  Journal of peptide science : an official publication of the European Peptide Society 20080701

• Hormone-sensitive lipase serine phosphorylation and glycerol exchange across skeletal muscle in lean and obese subjects: effect of beta-adrenergic stimulation.

  Diabetes 20080701

• Zfra is an inhibitor of Bcl-2 expression and cytochrome c release from the mitochondria.

  Cellular signalling 20080701

• Anti-apoptotic action of Wnt5a in dermal fibroblasts is mediated by the PKA signaling pathways.

  Cellular signalling 20080701

• Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells.

  Cellular signalling 20080701

• G-protein-dependent and -independent pathways regulate proteinase-activated receptor-2 mediated p65 NFkappaB serine 536 phosphorylation in human keratinocytes.

  Cellular signalling 20080701

• The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells.

  American journal of physiology. Renal physiology 20080701

• Vascular endothelial growth factor induces heat shock protein (HSP) 27 serine 82 phosphorylation and endothelial tubulogenesis via protein kinase D and independent of p38 kinase.

  Cellular signalling 20080701

• Akt stabilizes estrogen receptor alpha with the concomitant reduction in its transcriptional activity.

  Cellular signalling 20080701

• MEK1/2 induces STAT5-mediated germline transcription of the TCRgamma locus in response to IL-7R signaling.

  Journal of immunology (Baltimore, Md. : 1950) 20080701

• Potent anti-inflammatory and neuroprotective effects of TGF-beta1 are mediated through the inhibition of ERK and p47phox-Ser345 phosphorylation and translocation in microglia.

  Journal of immunology (Baltimore, Md. : 1950) 20080701

• A phosphatase cascade by which rewarding stimuli control nucleosomal response.

  Nature 20080612

• GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis.

  Journal of cellular physiology 20080601

• The type 2C phosphatase Wip1: an oncogenic regulator of tumor suppressor and DNA damage response pathways.

  Cancer metastasis reviews 20080601

• Polo-box domains confer target specificity to the Polo-like kinase family.

  Biochimica et biophysica acta 20080601

• The PIP2 binding mode of the C2 domains of rabphilin-3A.

  Protein science : a publication of the Protein Society 20080601

• Role of the C-terminal domain of RNA polymerase II in expression of small nuclear RNA genes.

  Biochemical Society transactions 20080601

• Trends in selenium utilization in marine microbial world revealed through the analysis of the global ocean sampling (GOS) project.

  PLoS genetics 20080601

• Reactivation of p53 by a specific MDM2 antagonist (MI-43) leads to p21-mediated cell cycle arrest and selective cell death in colon cancer.

  Molecular cancer therapeutics 20080601

• Phosphorylation of delta2 glutamate receptors at serine 945 is not required for cerebellar long-term depression.

  The Keio journal of medicine 20080601

• Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis.

  The Journal of biological chemistry 20080530

• Proton chemical shift anisotropy measurements of hydrogen-bonded functional groups by fast magic-angle spinning solid-state NMR spectroscopy.

  Chemical communications (Cambridge, England) 20080528

• Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis.

  The Journal of biological chemistry 20080523

• Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns.

  Cell cycle (Georgetown, Tex.) 20080515

• Sequential protein kinase C (PKC)-dependent and PKC-independent protein kinase D catalytic activation via Gq-coupled receptors: differential regulation of activation loop Ser(744) and Ser(748) phosphorylation.

  The Journal of biological chemistry 20080509

• A regulatory domain in the N terminus of tryptophan hydroxylase 2 controls enzyme expression.

  The Journal of biological chemistry 20080509

• TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation.

  Journal of molecular biology 20080509

• Hsp27 inhibits Bax activation and apoptosis via a phosphatidylinositol 3-kinase-dependent mechanism.

  The Journal of biological chemistry 20080502

• The Ser(186) phospho-acceptor site within ERK4 is essential for its ability to interact with and activate PRAK/MK5.

  The Biochemical journal 20080501

• Abrogation of hyperosmotic impairment of insulin signaling by a novel class of 1,2-dithiole-3-thiones through the inhibition of S6K1 activation.

  Molecular pharmacology 20080501

• Supramolecular structure of the casein micelle.

  Journal of dairy science 20080501

• Aminoacylation of tRNA with phosphoserine for synthesis of cysteinyl-tRNA(Cys).

  Nature structural & molecular biology 20080501

• Dentin phosphophoryn promotes cellular migration of human dental pulp cells.

  Journal of endodontics 20080501

• Interplay between acid phosphatase and cysteine proteases in mediating vitellin degradation during early embryogenesis of Periplaneta americana.

  Journal of insect physiology 20080501

• Embryonically expressed GABA and glutamate drive electrical activity regulating neurotransmitter specification.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080430

• Architecture of a serine recombinase-DNA regulatory complex.

  Molecular cell 20080425

• The identification and characterization of novel PKCepsilon phosphorylation sites provide evidence for functional cross-talk within the PKC superfamily.

  The Biochemical journal 20080415

• Dynamics of Recognition between tRNA and elongation factor Tu.

  Journal of molecular biology 20080411

• Calcineurin-mediated dephosphorylation of c-Jun Ser-243 is required for c-Jun protein stability and cell transformation.

  Oncogene 20080410

• Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein.

  The Journal of biological chemistry 20080404

• Kinase domain mutants of Bcr enhance Bcr-Abl oncogenic effects.

  Oncogene 20080403

• Prostatic-like acid phosphatase in human endometrial glands and its cyclic activity.

  Journal of molecular histology 20080401

• Differential regulation of IKK alpha-mediated activation of IRF3/7 by NIK.

  Molecular immunology 20080401

• cPLA2 phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells.

  Journal of lipid research 20080401

• Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages.

  Molecular and cellular biology 20080401

• Role of vasodilator-stimulated phosphoprotein in cGMP-mediated protection of human pulmonary artery endothelial barrier function.

  American journal of physiology. Lung cellular and molecular physiology 20080401

• The properties of phosphodiesterase 11A4 GAF domains are regulated by modifications in its N-terminal domain.

  The FEBS journal 20080401

• Selective roles of MAPKs during the macrophage response to IFN-gamma.

  Journal of immunology (Baltimore, Md. : 1950) 20080401

• Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis.

  Journal of immunology (Baltimore, Md. : 1950) 20080401

• Binding-induced folding of a natively unstructured transcription factor.

  PLoS computational biology 20080401

• Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes.

  Journal of the American Chemical Society 20080326

• Plx1 is required for chromosomal DNA replication under stressful conditions.

  The EMBO journal 20080319

• A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1.

  Molecular cell 20080314

• 14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.

  FEBS letters 20080305

• Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues.

  FEBS letters 20080305

• Gymnemic acid interacts with mammalian glycerol-3-phosphate dehydrogenase.

  Molecular and cellular biochemistry 20080301

• Nuclear localization signal and phosphorylation of Serine350 specify intracellular localization of DRAK2.

  Journal of biochemistry 20080301

• The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats.

  Neuropharmacology 20080301

• Isoform-specific defects of insulin stimulation of Akt/protein kinase B (PKB) in skeletal muscle cells from type 2 diabetic patients.

  Diabetologia 20080301

• Phosphorylation mediates Sp1 coupled activities of proteolytic processing, desumoylation and degradation.

  Cell cycle (Georgetown, Tex.) 20080301

• Analysis of the cell adhesion molecule sticks-and-stones reveals multiple redundant functional domains, protein-interaction motifs and phosphorylated tyrosines that direct myoblast fusion in Drosophila melanogaster.

  Genetics 20080301

• Akt inactivates ERK causing decreased response to chemotherapeutic drugs in advanced CaP cells.

  Cell cycle (Georgetown, Tex.) 20080301

• Metabolism of halophilic archaea.

  Extremophiles : life under extreme conditions 20080301

• In situ observation of protein phosphorylation by high-resolution NMR spectroscopy.

  Nature structural & molecular biology 20080301

• Structure of mouse ADP-ribosylhydrolase 3 (mARH3).

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080301

• Structure and catalytic mechanism of eukaryotic selenocysteine synthase.

  The Journal of biological chemistry 20080227

• Crystal structure of lactoperoxidase at 2.4 A resolution.

  Journal of molecular biology 20080227

• Identification of p32 as a novel substrate for ATM in heart.

  Biochemical and biophysical research communications 20080222

• Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo.

  Circulation 20080219

• Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metformin-enhanced activation of the AMP-activated protein kinase in endothelial cells.

  Circulation 20080219

• C1q binds phosphatidylserine and likely acts as a multiligand-bridging molecule in apoptotic cell recognition.

  Journal of immunology (Baltimore, Md. : 1950) 20080215

• G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer.

  British journal of cancer 20080212

• Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells.

  Nature 20080207

• Group III metabotropic glutamate receptors act as hetero-receptors modulating evoked GABA release in the globus pallidus in vivo.

  European journal of pharmacology 20080202

• PKD, PKD2, and p38 MAPK mediate Hsp27 serine-82 phosphorylation induced by neurotensin in pancreatic cancer PANC-1 cells.

  Journal of cellular biochemistry 20080201

• MEK1 and MEK2 regulate distinct functions by sorting ERK2 to different intracellular compartments.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080201

• Lovastatin sensitized human glioblastoma cells to TRAIL-induced apoptosis.

  Journal of neuro-oncology 20080201

• Impaired photosystem I oxidation induces STN7-dependent phosphorylation of the light-harvesting complex I protein Lhca4 in Arabidopsis thaliana.

  Planta 20080201

• Cyclin-dependent kinase phosphorylation of RUNX1/AML1 on 3 sites increases transactivation potency and stimulates cell proliferation.

  Blood 20080201

• Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response.

  Aging cell 20080201

• Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes.

  Journal of molecular and cellular cardiology 20080201

• Analysis of the Rem2 - voltage dependant calcium channel beta subunit interaction and Rem2 interaction with phosphorylated phosphatidylinositide lipids.

  Cellular signalling 20080201

• A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media.

  Journal of proteome research 20080201

• Mechanistic insights into the multistage gas-phase fragmentation behavior of phosphoserine- and phosphothreonine-containing peptides.

  Journal of proteome research 20080201

• Disruption of PDGFRalpha-initiated PI3K activation and migration of somite derivatives leads to spina bifida.

  Development (Cambridge, England) 20080201

• Ectopic histone H3S10 phosphorylation causes chromatin structure remodeling in Drosophila.

  Development (Cambridge, England) 20080201

• Dok1 mediates high-fat diet-induced adipocyte hypertrophy and obesity through modulation of PPAR-gamma phosphorylation.

  Nature medicine 20080201

• Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma.

  International journal of molecular medicine 20080201

• Dual role of proapoptotic BAD in insulin secretion and beta cell survival.

  Nature medicine 20080201

• Transcription-dependent gene looping of the HIV-1 provirus is dictated by recognition of pre-mRNA processing signals.

  Molecular cell 20080118

• Phosphorylation-dependent binding of cyclin B1 to a Cdc6-like domain of human separase.

  The Journal of biological chemistry 20080111

• Fibrous and helical calcite crystals induced by synthetic polypeptides containing o-phospho-L-serine and o-phospho-L-threonine.

  Macromolecular bioscience 20080109

• Claudin-16 is directly phosphorylated by protein kinase A independently of a vasodilator-stimulated phosphoprotein-mediated pathway.

  Journal of cellular physiology 20080101

• Cadmium induces mitochondria-dependent apoptosis of normal human hepatocytes.

  Cell biology and toxicology 20080101

• Activation of a polyvalent cation-sensing receptor decreases magnesium transport via claudin-16.

  Biochimica et biophysica acta 20080101

• DNA-PK contributes to the phosphorylation of AIRE: importance in transcriptional activity.

  Biochimica et biophysica acta 20080101

• Amyloid beta-peptide 31-35-induced neuronal apoptosis is mediated by caspase-dependent pathways via cAMP-dependent protein kinase A activation.

  Aging cell 20080101

• A new biomarker for mitotic cells.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20080101

• GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.

  Cancer cell 20080101

• Human 14-3-3 gamma protein results in abnormal cell proliferation in the developing eye of Drosophila melanogaster.

  Cell division 20080101

• Yeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.

  PloS one 20080101

• Inhibition of transcription by the Caenorhabditis elegans germline protein PIE-1: genetic evidence for distinct mechanisms targeting initiation and elongation.

  Genetics 20080101

• Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells.

  Molecular cancer 20080101

• Hsc70 focus formation at the periphery of HSV-1 transcription sites requires ICP27.

  PloS one 20080101

• Fine mapping of posttranslational modifications of the linker histone H1 from Drosophila melanogaster.

  PloS one 20080101

• The differentiation/retrodifferentiation program of human U937 leukemia cells is accompanied by changes of VCP/p97.

  BMC cell biology 20080101

• Protein tyrosine phosphatases: new markers and targets in oncology?

  Current oncology (Toronto, Ont.) 20080101

• The transactivation domain of heterogeneous nuclear ribonucleoprotein K overlaps its nuclear shuttling domain.

  The international journal of biochemistry & cell biology 20080101

• Charge environments around phosphorylation sites in proteins.

  BMC structural biology 20080101

• Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity.

  Molecular cancer 20080101

• Decorin derived antiangiogenic peptide LRR5 inhibits endothelial cell migration by interfering with VEGF-stimulated NO release.

  The international journal of biochemistry & cell biology 20080101

• 14-3-3 theta binding to cell cycle regulatory factors is enhanced by HIV-1 Vpr.

  Biology direct 20080101

• Large-scale phosphorylation mapping reveals the extent of tyrosine phosphorylation in Arabidopsis.

  Molecular systems biology 20080101

• Identification of serine phosphorylation in mitochondrial uncoupling protein 1.

  Biochimica et biophysica acta 20080101

• Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites.

  BMC bioinformatics 20080101

• PKC putative phosphorylation site Ser235 is required for MIP/AQP0 translocation to the plasma membrane.

  Molecular vision 20080101

• The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution.

  Genome biology 20080101

• Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats.

  Cardiovascular diabetology 20080101

• Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.

  BMC molecular biology 20080101

• Nerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neurons.

  PloS one 20080101

• Expression of clottable protein of tiger shrimp (Penaeus monodon) in gonads and its possible role as nutrient source for the embryo.

  Developmental and comparative immunology 20080101

• The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation.

  Genome biology 20080101

• The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins.

  BMC biochemistry 20080101

• Evolutionary patterns in the sequence and structure of transfer RNA: a window into early translation and the genetic code.

  PloS one 20080101

• A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death.

  PloS one 20080101

• Comparative phylogenomics and multi-gene cluster analyses of the Citrus Huanglongbing (HLB)-associated bacterium Candidatus Liberibacter.

  BMC research notes 20080101

• Shark skeletal muscle tropomyosin is a phosphoprotein.

  Journal of muscle research and cell motility 20080101

• Phosphorylation sites on Tyr28 and the C-terminus of Rad9 are required for inhibition of premature chromosomal condensation across the entire S phase.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101

• An extension of the coevolution theory of the origin of the genetic code.

  Biology direct 20080101

• In GFP with high risk HPV-18E6 fusion protein expressed 293T and MCF-7 cells, the endogenous wild-type p53 could be transiently phosphorylated at multiple sites.

  Journal of experimental & clinical cancer research : CR 20080101

• The Krüppel-like factor 9 (KLF9) network in HEC-1-A endometrial carcinoma cells suggests the carcinogenic potential of dys-regulated KLF9 expression.

  Reproductive biology and endocrinology : RB&E 20080101

• Promoter binding by the Adr1 transcriptional activator may be regulated by phosphorylation in the DNA-binding region.

  PloS one 20080101

• The protein-phosphatome of the human malaria parasite Plasmodium falciparum.

  BMC genomics 20080101

• Identification of CDK2 substrates in human cell lysates.

  Genome biology 20080101

• A phosphotyrosine-imprinted polymer receptor for the recognition of tyrosine phosphorylated peptides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1.

  Breast cancer research : BCR 20080101

• G-CSFR ubiquitination critically regulates myeloid cell survival and proliferation.

  PloS one 20080101

• The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas.

  BMC cancer 20080101

• HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha.

  PloS one 20080101

• Displacement affinity chromatography of protein phosphatase one (PP1) complexes.

  BMC biochemistry 20080101

• Hereditary dentine disorders: dentinogenesis imperfecta and dentine dysplasia.

  Orphanet journal of rare diseases 20080101

• Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability.

  Molecular cancer 20080101

• Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics.

  BMC bioinformatics 20080101

• targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.

  BMC systems biology 20080101

• Phosphorylation regulates SIRT1 function.

  PloS one 20080101

• Detecting the site of phosphorylation in phosphopeptides without loss of phosphate group using MALDI TOF mass spectrometry.

  Analytical chemistry insights 20080101

• Serine phosphorylation-dependent coregulation of topoisomerase I by the p14ARF tumor suppressor.

  Biochemistry 20071211

• The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

  Experimental cell research 20071210

• Control of calcium oxalate crystal growth by face-specific adsorption of an osteopontin phosphopeptide.

  Journal of the American Chemical Society 20071205

• The tolerance property of human D3 dopamine receptor is determined by specific amino acid residues in the second cytoplasmic loop.

  Biochimica et biophysica acta 20071201

• Acinus-provoked protein kinase C delta isoform activation is essential for apoptotic chromatin condensation.

  Cell death and differentiation 20071201

• Transcriptional regulation of the androgen receptor cofactor androgen receptor trapped clone-27.

  Molecular endocrinology (Baltimore, Md.) 20071201

• Control of protein phosphorylation with a genetically encoded photocaged amino acid.

  Nature chemical biology 20071201

• Understanding marine mussel adhesion.

  Marine biotechnology (New York, N.Y.) 20071201

• Calcitonin targets extracellular signal-regulated kinase signaling pathway in human cancers.

  Journal of molecular endocrinology 20071201

• [Specific recognition and detection of phosphorylated proteins using characteristics of metal ion].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071201

• Phosphorylation-regulated cleavage of the reticulon protein Nogo-B by caspase-7 at a noncanonical recognition site.

  Proteomics 20071201

• Generation and characterization of a novel phospho-specific monoclonal antibody to p120-catenin serine 879.

  Hybridoma (2005) 20071201

• [Expression and significance of Ser10 phosphorylated p27(kip1) and JAB1 protein in human hepatocellular carcinoma].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20071201

• GSK-3-mediated phosphorylation enhances Maf-transforming activity.

  Molecular cell 20071130

• Phosphopeptide elution times in reversed-phase liquid chromatography.

  Journal of chromatography. A 20071116

• The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways.

  International journal of cancer 20071115

• Enhancement by lithium of cAMP-induced CRE/CREB-directed gene transcription conferred by TORC on the CREB basic leucine zipper domain.

  The Biochemical journal 20071115

• Identification of Tim4 as a phosphatidylserine receptor.

  Nature 20071115

• Design, synthesis, and evaluation of linear and cyclic peptide ligands for PDZ10 of the multi-PDZ domain protein MUPP1.

  Biochemistry 20071106

• The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.

  Biochemistry 20071106

• Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.

  Cellular signalling 20071101

• Proteomic approach for caudal trauma-induced acute phase proteins reveals that creatine kinase is a key acute phase protein in amphioxus humoral fluid.

  Journal of proteome research 20071101

• Capillary electrophoresis of phosphorylated amino acids with fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

• Protein phosphorylation in irradiated human melanoma cells.

  Radiation research 20071101

• Regulation of cell cycle progression and gene expression by H2A deubiquitination.

  Nature 20071025

• Replication stress, defective S-phase checkpoint and increased death in Plk2-deficient human cancer cells.

  Cell cycle (Georgetown, Tex.) 20071015

• Liquid chromatographic analysis of phosphoamino acids at femtomole level using chemical derivatization with N-hydroxysuccinimidyl fluorescein-O-acetate.

  Analytica chimica acta 20071003

• Casein kinase 2 is the major enzyme in brain that phosphorylates Ser129 of human alpha-synuclein: Implication for alpha-synucleinopathies.

  FEBS letters 20071002

• [The spliceosome and its interest for lupus therapy].

  La Revue de medecine interne 20071001

• Molecular basis for isoform-specific autoregulation of protein kinase A.

  Cellular signalling 20071001

• Inhibition of estrogen receptor beta-mediated human telomerase reverse transcriptase gene transcription via the suppression of mitogen-activated protein kinase signaling plays an important role in 15-deoxy-Delta(12,14)-prostaglandin J(2)-induced apoptosis in cancer cells.

  Experimental cell research 20071001

• 17Beta-oestradiol partially attenuates the inhibition of nitric oxide synthase-3 by advanced glycation end-products in human platelets.

  Clinical and experimental pharmacology & physiology 20071001

• 14-3-3-dependent inhibition of the deubiquitinating activity of UBPY and its cancellation in the M phase.

  Experimental cell research 20071001

• Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro.

  Biochemical and biophysical research communications 20070921

• Effects of dietary calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice.

  The Journal of biological chemistry 20070921

• Rho-kinase phosphorylates eNOS at threonine 495 in endothelial cells.

  Biochemical and biophysical research communications 20070921

• DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.

  Oncogene 20070906

• Calcium mobilization via type III inositol 1,4,5-trisphosphate receptors is not altered by PKA-mediated phosphorylation of serines 916, 934, and 1832.

  Cell calcium 20070901

• One-trial in vitro conditioning of hermissenda regulates phosphorylation of ser-122 of csp24.

  Annals of the New York Academy of Sciences 20070901

• Phosphorylation and ubiquitination are necessary for Na,K-ATPase endocytosis during hypoxia.

  Cellular signalling 20070901

• Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury.

  Cellular signalling 20070901

• Phosphorylation at Ser729 specifies a Golgi localisation for protein kinase C epsilon (PKCepsilon) in 3T3 fibroblasts.

  Cellular signalling 20070901

• An 'orphan' finds a home in NSC regulation.

  Chemistry & biology 20070901

• A phenotypic small-molecule screen identifies an orphan ligand-receptor pair that regulates neural stem cell differentiation.

  Chemistry & biology 20070901

• Phosphorylation at carboxyl-terminal S373 and S375 residues and 14-3-3 binding are not required for mouse p53 function.

  Neoplasia (New York, N.Y.) 20070901

• Phosphorylation of serine-515 activates the Mammalian maintenance methyltransferase Dnmt1.

  Epigenetics 20070901

• Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukaemia lymphocytes.

  Cancer letters 20070808

• ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction by butyrate.

  Biochemical and biophysical research communications 20070803

• Regulation of matrix metalloproteinase-2 (MMP-2) activity by phosphorylation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070801

• Phosphoserine phosphatase is expressed in the neural stem cell niche and regulates neural stem and progenitor cell proliferation.

  Stem cells (Dayton, Ohio) 20070801

• Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.

  Diabetes 20070801

• Impulse-driven heated-droplet deposition interface for capillary and microbore LC-MALDI MS and MS/MS.

  Analytical chemistry 20070801

• Prognosis-determinant candidate genes identified by whole genome scanning in eyes with pterygia.

  Investigative ophthalmology & visual science 20070801

• Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage.

  Nucleic acids research 20070801

• Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.

  Molecular cancer therapeutics 20070801

• Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology.

  The Journal of biological chemistry 20070727

• Novel phosphorylation site markers of protein kinase C delta activation.

  FEBS letters 20070724

• Differential effects of phosphorylation on DNA binding properties of N Oct-3 are dictated by protein/DNA complex structures.

  Journal of molecular biology 20070720

• Increased phosphorylation of p70 S6 kinase is associated with HPV16 infection in cervical cancer and esophageal cancer.

  British journal of cancer 20070716

• Phosphomimetic mutation of the mitotically phosphorylated serine 1880 compromises the interaction of the transmembrane nucleoporin gp210 with the nuclear pore complex.

  Experimental cell research 20070715

• Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II.

  Journal of medicinal chemistry 20070712

• Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53.

  The EMBO journal 20070711

• SIRT1 regulates the function of the Nijmegen breakage syndrome protein.

  Molecular cell 20070706

• TNF-alpha-induced NF-kappaB/RelA Ser(276) phosphorylation and enhanceosome formation is mediated by an ROS-dependent PKAc pathway.

  Cellular signalling 20070701

• Ginkgo biloba extract EGb 761 increases endothelial nitric oxide production in vitro and in vivo.

  Cellular and molecular life sciences : CMLS 20070701

• Lithium toxicity and expression of stress-related genes or proteins in A549 cells.

  Biochimica et biophysica acta 20070701

• Improving fragmentation of poorly fragmenting peptides and phosphopeptides during collision-induced dissociation by malondialdehyde modification of arginine residues.

  Journal of mass spectrometry : JMS 20070701

• An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS.

  Molecular microbiology 20070701

• The role of protein kinase A in acute ethanol-induced neurobehavioral actions in rats.

  Anesthesia and analgesia 20070701

• Mass spectrometric studies on mouse hippocampal synapsins Ia, IIa, and IIb and identification of a novel phosphorylation site at serine-546.

  Journal of proteome research 20070701

• PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1.

  PLoS biology 20070701

• Structural insights into the second step of RNA-dependent cysteine biosynthesis in archaea: crystal structure of Sep-tRNA:Cys-tRNA synthase from Archaeoglobus fulgidus.

  Journal of molecular biology 20070629

• Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

  Nature 20070621

• PKCepsilon increases phosphorylation of the cardiac myosin binding protein C at serine 302 both in vitro and in vivo.

  Biochemistry 20070612

• The effect of intrahippocampal injection of group II and III metobotropic glutamate receptor agonists on anxiety; the role of neuropeptide Y.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070601

• Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors.

  Molecular and cellular biochemistry 20070601

• The effect of estrogen on phosphorylation of prolactin in the mouse pituitary gland.

  The Journal of reproduction and development 20070601

• Ankyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity.

  Cellular signalling 20070601

• Global assessment of regulation of phosphorylation of insulin receptor substrate-1 by insulin in vivo in human muscle.

  Diabetes 20070601

• Enhancement of ionization efficiency and selective enrichment of phosphorylated peptides from complex protein mixtures using a reversible poly-histidine tag.

  Journal of the American Society for Mass Spectrometry 20070601

• FcepsilonRI and Thy-1 domains have unique protein and lipid compositions.

  Journal of lipid research 20070601

• Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.

  Nature immunology 20070601

• Pin1 in neuronal apoptosis.

  Cell cycle (Georgetown, Tex.) 20070601

• O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII.

  The AAPS journal 20070601

• A multiplexed protein kinase assay.

  Chembiochem : a European journal of chemical biology 20070525

• Identification of a molecular target for the Yersinia protein kinase A.

  Molecular cell 20070525

• The in vivo phosphorylation sites of rat brain dynamin I.

  The Journal of biological chemistry 20070518

• Double phosphorylation of the myosin regulatory light chain during rigor mortis of bovine Longissimus muscle.

  Journal of agricultural and food chemistry 20070516

• Lysophospholipids of different classes mobilize neutrophil secretory vesicles and induce redundant signaling through G2A.

  Journal of immunology (Baltimore, Md. : 1950) 20070515

• Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans.

  Biochemistry 20070508

• Calcium phosphate bone cements, functionalized with VEGF: release kinetics and biological activity.

  Journal of biomedical materials research. Part A 20070501

• Regulation of the metastasis suppressor gene MKK4 in ovarian cancer.

  Gynecologic oncology 20070501

• Uranium(VI) complexes with phospholipid model compounds--a laser spectroscopic study.

  Journal of inorganic biochemistry 20070501

• C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A.

  Cell death and differentiation 20070501

• Phosphoserine aminotransferase deficiency: a novel disorder of the serine biosynthesis pathway.

  American journal of human genetics 20070501

• C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB.

  Immunity 20070501

• Arabidopsis protein kinase PKS5 inhibits the plasma membrane H+ -ATPase by preventing interaction with 14-3-3 protein.

  The Plant cell 20070501

• Identification of novel substrates for human checkpoint kinase Chk1 and Chk2 through genome-wide screening using a consensus Chk phosphorylation motif.

  Experimental & molecular medicine 20070430

• A direct link of the Mos-MAPK pathway to Erp1/Emi2 in meiotic arrest of Xenopus laevis eggs.

  Nature 20070426

• Mitosis-specific MPM-2 phosphorylation of DNA topoisomerase IIalpha is regulated directly by protein phosphatase 2A.

  The Biochemical journal 20070415

• Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.

  The Journal of biological chemistry 20070413

• Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission.

  The Journal of biological chemistry 20070413

• CMTM8 induces caspase-dependent and -independent apoptosis through a mitochondria-mediated pathway.

  Journal of cellular physiology 20070401

• Polar head groups are important for barrier-protective effects of oxidized phospholipids on pulmonary endothelium.

  American journal of physiology. Lung cellular and molecular physiology 20070401

• Structural determinants of LL5beta subcellular localisation and association with filamin C.

  Cellular signalling 20070401

• Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.

  Journal of cellular physiology 20070401

• Effect of modification of hydroxyapatite/collagen composites with sodium citrate, phosphoserine, phosphoserine/RGD-peptide and calcium carbonate on bone remodelling.

  Bone 20070401

• CCK causes PKD1 activation in pancreatic acini by signaling through PKC-delta and PKC-independent pathways.

  Biochimica et biophysica acta 20070401

• Activation of caspase 3 in HepG2 cells by elaidic acid (t18:1).

  Biochimica et biophysica acta 20070401

• Structural insights into the first step of RNA-dependent cysteine biosynthesis in archaea.

  Nature structural & molecular biology 20070401

• Two waves of the nuclear phospholipase C activity in serum-stimulated HL-60 cells during G(1) phase of the cell cycle.

  Biochimica et biophysica acta 20070401

• Phosphotyrosine/phosphoserine binary switches: a new paradigm for the regulation of PI3K signalling and growth factor pleiotropy?

  Biochemical Society transactions 20070401

• An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells.

  Molecular bioSystems 20070401

• Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase-mediated p53 phosphorylation and stabilization.

  Molecular cancer therapeutics 20070401

• Recruitment of P-TEFb (Cdk9-Pch1) to chromatin by the cap-methyl transferase Pcm1 in fission yeast.

  The EMBO journal 20070321

• Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS.

  The Biochemical journal 20070315

• DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.

  Molecular cell 20070309

• MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

  Molecular cell 20070309

• Prostate-derived sterile 20-like kinase 1-alpha induces apoptosis. JNK- and caspase-dependent nuclear localization is a requirement for membrane blebbing.

  The Journal of biological chemistry 20070302

• Glycogen synthase kinase-3beta binds to E2F1 and regulates its transcriptional activity.

  Biochimica et biophysica acta 20070301

• Acute impairment of insulin signalling by dexamethasone in primary cultured rat skeletal myocytes.

  Molecular and cellular biochemistry 20070301

• Approach to systematic analysis of serine/threonine phosphoproteome using Beta elimination and subsequent side effects: intramolecular linkage and/or racemisation.

  Journal of cellular biochemistry 20070301

• Effect of HPr phosphorylation on structure, dynamics, and interactions in the course of transcriptional control.

  Journal of molecular modeling 20070301

• Temporal dissociation of frequency-dependent acceleration of relaxation and protein phosphorylation by CaMKII.

  Journal of molecular and cellular cardiology 20070301

• Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein.

  Biochimica et biophysica acta 20070301

• [Shigella flexneri modulates host cell epigenetic information as a strategy to shape the transcriptional response].

  Medecine sciences : M/S 20070301

• Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators.

  The Journal of steroid biochemistry and molecular biology 20070301

• Dynamics of protein kinase C-mediated phosphorylation of the complement C5a receptor on serine 334.

  The Journal of biological chemistry 20070216

• Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis.

  The Journal of biological chemistry 20070216

• Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking.

  The Journal of biological chemistry 20070216

• Ancestral sequence evolutionary trace and crystal structure analyses of alkaline alpha-amylase from Bacillus sp. KSM-1378 to clarify the alkaline adaptation process of proteins.

  Proteins 20070215

• Evidence for the location of the allosteric activation switch in the multisubunit phosphorylase kinase complex from mass spectrometric identification of chemically crosslinked peptides.

  Journal of molecular biology 20070202

• Cdk5 regulates STAT3 activation and cell proliferation in medullary thyroid carcinoma cells.

  The Journal of biological chemistry 20070202

• Cloning and characterization of a plastidic glycerol 3-phosphate dehydrogenase cDNA from Dunaliella salina.

  Journal of plant physiology 20070201

• p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis.

  Cell death and differentiation 20070201

• Mobile phone base station-emitted radiation does not induce phosphorylation of Hsp27.

  Bioelectromagnetics 20070201

• c-Src interacts with and phosphorylates RelA/p65 to promote thrombin-induced ICAM-1 expression in endothelial cells.

  American journal of physiology. Lung cellular and molecular physiology 20070201

• Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070201

• Effects of (S)-3,4-DCPG, an mGlu8 receptor agonist, on inflammatory and neuropathic pain in mice.

  Neuropharmacology 20070201

• Quantitative proteomic approaches for studying phosphotyrosine signaling.

  Expert review of proteomics 20070201

• [VE-cadherin takes a walk on the wild side].

  Medecine sciences : M/S 20070201

• Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.

  Structure (London, England : 1993) 20070201

• Synthesis, platelet adhesion and cytotoxicity studies of new glycerophosphoryl-containing polyurethanes.

  The International journal of artificial organs 20070201

• Lithium regulates glycogen synthase kinase-3beta in human peripheral blood mononuclear cells: implication in the treatment of bipolar disorder.

  Biological psychiatry 20070115

• Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells.

  Journal of immunology (Baltimore, Md. : 1950) 20070115

• The Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and export.

  Genes & development 20070115

• Gcn5 promotes acetylation, eviction, and methylation of nucleosomes in transcribed coding regions.

  Molecular cell 20070112

• Involvement of PKCalpha in insulin-induced PKCdelta expression: Importance of SP-1 and NFkappaB transcription factors.

  Biochemical and biophysical research communications 20070105

• The Trk tyrosine kinase inhibitor K252a regulates growth of lung adenocarcinomas.

  Molecular and cellular biochemistry 20070101

• Role of protein phosphatase 2A in calcium-dependent chloride secretion by human colonic epithelial cells.

  American journal of physiology. Cell physiology 20070101

• Immunoassay of serine-phosphorylated isoform of insulin-like growth factor (IGF) binding protein (IGFBP)-1.

  Clinical biochemistry 20070101

• Selective activation of group III metabotropic glutamate receptors by L-(+)-2-amino-4-phosphonobutryic acid protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.

  The Journal of pharmacology and experimental therapeutics 20070101

• Characterization of beta2-adrenergic receptor dephosphorylation: Comparison with the rate of resensitization.

  Molecular pharmacology 20070101

• Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation.

  The Journal of pharmacology and experimental therapeutics 20070101

• Troponin phosphorylation and regulatory function in human heart muscle: dephosphorylation of Ser23/24 on troponin I could account for the contractile defect in end-stage heart failure.

  Journal of molecular and cellular cardiology 20070101

• Focus on phosphohistidine.

  Amino acids 20070101

• Raf kinase inhibitor protein affects activity of Plasmodium falciparum calcium-dependent protein kinase 1.

  Molecular and biochemical parasitology 20070101

• A sharper instrument for dissecting signalling events: a specific AGC kinase inhibitor.

  The Biochemical journal 20070101

• DNA damage-induced Bcl-xL deamidation is mediated by NHE-1 antiport regulated intracellular pH.

  PLoS biology 20070101

• Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress.

  The Journal of cell biology 20070101

• Biosynthesis of selenocysteine on its tRNA in eukaryotes.

  PLoS biology 20070101

• Stress-associated MAP kinase fills in the map of filamin-mediated neuronal migration.

  Developmental cell 20070101

• pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model.

  Biology direct 20070101

• Effect of carboxylate-binding mode on metal binding/selectivity and function in proteins.

  Accounts of chemical research 20070101

• Analysis of mitotic phosphorylation of borealin.

  BMC cell biology 20070101

• Fbw7/hCDC4 dimerization regulates its substrate interactions.

  Cell division 20070101

• Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.

  Molecular cancer 20070101

• Baculovirus-mediated gene transfer and recombinant protein expression do not interfere with insulin dependent phosphorylation of PKB/Akt in human SHSY-5Y and C3A cells.

  BMC cell biology 20070101

• The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function.

  BMC genomics 20070101

• Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells.

  Cancer cell international 20070101

• [Role of c-Jun NH (2)-terminal kinase in insulin resistance after burn].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20070101

• Bioinformatics strategies for lipidomics analysis: characterization of obesity related hepatic steatosis.

  BMC systems biology 20070101

• p42MAPK-mediated phosphorylation of xEIAP/XLX in Xenopus cytostatic factor-arrested egg extracts.

  BMC biochemistry 20070101

• Flexible mapping of homology onto structure with homolmapper.

  BMC bioinformatics 20070101

• Deletion of the cruciform binding domain in CBP/14-3-3 displays reduced origin binding and initiation of DNA replication in budding yeast.

  BMC molecular biology 20070101

• New perspectives on an old disease: proteomics in cancer research.

  Genome biology 20070101

• Cdc25 and Wee1: analogous opposites?

  Cell division 20070101

• Involvement of glycogen synthase kinase-3beta in palmitate-induced human umbilical vein endothelial cell apoptosis.

  Journal of vascular research 20070101

• Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli.

  BMC bioinformatics 20070101

• NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation.

  BMC genomics 20070101

• Arginine-mimic labeling with guanidinoethanethiol to increase mass sensitivity of lysine-terminated phosphopeptides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Cyclic AMP signalling pathways in the regulation of uterine relaxation.

  BMC pregnancy and childbirth 20070101

• Anti-free-radical properties of the peptide fractions isolated from string bean by immobilized metal ion affinity chromatography.

  Protein and peptide letters 20070101

• ATM activation accompanies histone H2AX phosphorylation in A549 cells upon exposure to tobacco smoke.

  BMC cell biology 20070101

• Neurite outgrowth on a fibronectin isoform expressed during peripheral nerve regeneration is mediated by the interaction of paxillin with alpha4beta1 integrins.

  BMC neuroscience 20070101

• p53 target gene SMAR1 is dysregulated in breast cancer: its role in cancer cell migration and invasion.

  PloS one 20070101

• Analysis of the Rana catesbeiana tadpole tail fin proteome and phosphoproteome during T3-induced apoptosis: identification of a novel type I keratin.

  BMC developmental biology 20070101

• A novel DSPP mutation is associated with type II dentinogenesis imperfecta in a Chinese family.

  BMC medical genetics 20070101

• UDP-acetyl-mannosamine dehydrogenase is an endogenous protein substrate of Staphylococcus aureus protein-tyrosine kinase activity.

  Journal of molecular microbiology and biotechnology 20070101

• Phosphorylation of Ser78 of Hsp27 correlated with HER-2/neu status and lymph node positivity in breast cancer.

  Molecular cancer 20070101

• GSK-3 inhibitors induce chromosome instability.

  BMC cell biology 20070101

• Microbial proteomics: a mass spectrometry primer for biologists.

  Microbial cell factories 20070101

• Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein--a genetic, biochemical and biophysical analysis.

  Virology journal 20070101

• ODF1 phosphorylation by Cdk5/p35 enhances ODF1-OIP1 interaction.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20070101

• Over-expression of 14-3-3zeta is an early event in oral cancer.

  BMC cancer 20070101

• CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72.

  PloS one 20070101

• GSK-3beta controls osteogenesis through regulating Runx2 activity.

  PloS one 20070101

• Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy.

  Breast cancer research : BCR 20070101

• Disappearance of interfering alkali-metal adducted peaks from matrix-assisted laser desorption/ionization mass spectra of peptides with serine addition to alpha-cyano-4-hydroxycinnamic acid matrix.

  Rapid communications in mass spectrometry : RCM 20070101

• Constitutive phosphorylation of aurora-a on ser51 induces its stabilization and consequent overexpression in cancer.

  PloS one 20070101

• Urodele p53 tolerates amino acid changes found in p53 variants linked to human cancer.

  BMC evolutionary biology 20070101

• Abundance and functional diversity of riboswitches in microbial communities.

  BMC genomics 20070101

• Phosphoprotein phosphatase-2A docks to Dishevelled and counterregulates Wnt3a/beta-catenin signaling.

  Journal of molecular signaling 20070101

• Importance of spliceosomal RNP1 motif for intermolecular T-B cell spreading and tolerance restoration in lupus.

  Arthritis research & therapy 20070101

• Phosphorylated GSK3beta-ser9 and EGFR are good prognostic factors for lung carcinomas.

  Anticancer research 20070101

• UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures.

  BMC plant biology 20070101

• Synergism between AT1 receptor and hyperhomocysteinemia during vascular remodeling.

  Clinical chemistry and laboratory medicine 20070101

• Coupling of TiO(2)-mediated enrichment and on-bead guanidinoethanethiol labeling for effective phosphopeptide analysis by matrix-assisted laser desorption/ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites.

  Genome biology 20070101

• The TriTryp phosphatome: analysis of the protein phosphatase catalytic domains.

  BMC genomics 20070101

• Stress preconditioning of spreading depression in the locust CNS.

  PloS one 20070101

• Phosphopeptide modification and enrichment by oxidation-reduction condensation.

  ACS chemical biology 20061220

• KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions.

  Cancer research 20061215

• Asbestos redirects nitric oxide signaling through rapid catalytic conversion to nitrite.

  Cancer research 20061215

• ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.

  The EMBO journal 20061213

• Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation.

  The EMBO journal 20061213

• Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesis.

  Oncogene 20061207

• Differential effects of systemic ethanol administration on protein kinase cepsilon, gamma, and beta isoform expression, membrane translocation, and target phosphorylation: reversal by chronic ethanol exposure.

  The Journal of pharmacology and experimental therapeutics 20061201

• Post-translational control of Nur77.

  Biochemical Society transactions 20061201

• Protein phosphatases types 2Calpha and 2Cbeta in apoptosis.

  Biochemical Society transactions 20061201

• Ser46 phosphorylation regulates p53-dependent apoptosis and replicative senescence.

  Cell cycle (Georgetown, Tex.) 20061201

• TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner.

  Cell cycle (Georgetown, Tex.) 20061201

• Human Cdc14A reverses CDK1 phosphorylation of Cdc25A on serines 115 and 320.

  Cell cycle (Georgetown, Tex.) 20061201

• Phosphorylation of specific serine residues in the PKR activation domain of PACT is essential for its ability to mediate apoptosis.

  The Journal of biological chemistry 20061117

• Critical role of vimentin phosphorylation at Ser-56 by p21-activated kinase in vimentin cytoskeleton signaling.

  The Journal of biological chemistry 20061110

• Signaling pathways regulating murine cardiac CREB phosphorylation.

  Biochemical and biophysical research communications 20061110

• The NR4A orphan nuclear receptor NOR1 is induced by platelet-derived growth factor and mediates vascular smooth muscle cell proliferation.

  The Journal of biological chemistry 20061103

• Identification of MAPK phosphorylation sites and their role in the localization and activity of hypoxia-inducible factor-1alpha.

  The Journal of biological chemistry 20061103

• Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation.

  The Journal of biological chemistry 20061103

• Osteoclast differentiation requires TAK1 and MKK6 for NFATc1 induction and NF-kappaB transactivation by RANKL.

  Cell death and differentiation 20061101

• Ser58 of mouse p53 is the homologue of human Ser46 and is phosphorylated by HIPK2 in apoptosis.

  Cell death and differentiation 20061101

• Modulation of ceramide metabolism enhances viral protein apoptin's cytotoxicity in prostate cancer.

  Molecular therapy : the journal of the American Society of Gene Therapy 20061101

• Melatonin modulates signal transduction pathways and apoptosis in experimental colitis.

  Journal of pineal research 20061101

• The metabolic significance of octulose phosphates in the photosynthetic carbon reduction cycle in spinach.

  Photosynthesis research 20061101

• Identification of two forms of vitellogenin-derived phosvitin and elucidation of their fate and roles during oocyte maturation in the barfin flounder, Verasper moseri.

  Zoological science 20061101

• Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II).

  Purinergic signalling 20061101

• PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function.

  Biochemical and biophysical research communications 20061027

• Myc stabilization in response to estrogen and phospholipase D in MCF-7 breast cancer cells.

  FEBS letters 20061016

• Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver.

  FEBS letters 20061016

• In situ phosphorylation of immobilized receptors on biosensor surfaces: application to E-cadherin/beta-catenin interactions.

  Analytical biochemistry 20061015

• CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage.

  Science (New York, N.Y.) 20061013

• Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.

  Oncogene 20061012

• Antineoplastic effects of rosiglitazone and PPARgamma transactivation in neuroblastoma cells.

  British journal of cancer 20061009

• STD and TRNOESY NMR studies for the epitope mapping of the phosphorylation motif of the oncogenic protein beta-catenin recognized by a selective monoclonal antibody.

  FEBS letters 20061002

• PITK, a PP1 targeting subunit that modulates the phosphorylation of the transcriptional regulator hnRNP K.

  Cellular signalling 20061001

• AKT can be activated in the nucleus.

  Cellular signalling 20061001

• Hypertonicity activates GSK3beta in tumor cells.

  Molecular and cellular biochemistry 20061001

• Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress.

  Diabetologia 20061001

• Supercell and subcell description of the crystal structure of triammonium bis(O-phospho-L-serinate) trihydrate.

  Acta crystallographica. Section B, Structural science 20061001

• Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo.

  Nature 20060914

• Regulation of connexin-43-mediated growth inhibition by a phosphorylatable amino-acid is independent of gap junction-forming ability.

  Molecular and cellular biochemistry 20060901

• Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine.

  The Journal of biological chemistry 20060901

• Context-dependent regulation of embryonic stem cell differentiation by mGlu4 metabotropic glutamate receptors.

  Neuropharmacology 20060901

• Ethanol inhibition of NMDA-induced responses and acute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases.

  Neuropharmacology 20060901

• Mutations of phosphorylation sites Ser10 and Thr187 of p27Kip1 abolish cytoplasmic redistribution but do not abrogate G0/1 phase arrest in the HepG2 cell line.

  Biochemical and biophysical research communications 20060901

• Characterization of a tyrosine phosphatase activity in the oogenesis of Periplaneta americana.

  Archives of insect biochemistry and physiology 20060901

• The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1.

  Genes to cells : devoted to molecular & cellular mechanisms 20060901

• Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.

  Molecular cell 20060901

• Wip1 phosphatase modulates ATM-dependent signaling pathways.

  Molecular cell 20060901

• Royal jelly prevents osteoporosis in rats: beneficial effects in ovariectomy model and in bone tissue culture model.

  Evidence-based complementary and alternative medicine : eCAM 20060901

• Phosphorylation of ERalpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ERalpha phosphorylation in breast cancer progression.

  Endocrine-related cancer 20060901

• Histone phosphorylation and pericentromeric histone modifications in oocyte meiosis.

  Cell cycle (Georgetown, Tex.) 20060901

• Learning induces long-term potentiation in the hippocampus.

  Science (New York, N.Y.) 20060825

• ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.

  Science (New York, N.Y.) 20060825

• Graded regulation of the Kv2.1 potassium channel by variable phosphorylation.

  Science (New York, N.Y.) 20060818

• Single crystals of L-O-serine phosphate X-irradiated at low temperatures: EPR, ENDOR, EIE, and DFT studies.

  The journal of physical chemistry. A 20060810

• Involvement of novel autophosphorylation sites in ATM activation.

  The EMBO journal 20060809

• Sic1 is phosphorylated by CK2 on Ser201 in budding yeast cells.

  Biochemical and biophysical research communications 20060804

• Neighbored phosphorylation sites as PHF-tau specific markers in Alzheimer's disease.

  Biochemical and biophysical research communications 20060804

• beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870.

  Cellular signalling 20060801

• Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.

  Molecular endocrinology (Baltimore, Md.) 20060801

• Activation of Group II/III metabotropic glutamate receptors attenuates LPS-induced astroglial neurotoxicity via promoting glutamate uptake.

  Journal of neuroscience research 20060801

• Abundance of the largest subunit of RNA polymerase II in the nucleus is regulated by nucleo-cytoplasmic shuttling.

  Experimental cell research 20060801

• Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.

  Cell cycle (Georgetown, Tex.) 20060801

• CDC25B phosphorylation by p38 and MK-2.

  Cell cycle (Georgetown, Tex.) 20060801

• Nitrogen oxide-releasing aspirin induces histone H2AX phosphorylation, ATM activation and apoptosis preferentially in S-phase cells: involvement of reactive oxygen species.

  Cell cycle (Georgetown, Tex.) 20060801

• Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin.

  Diabetes 20060801

• The Bloom syndrome helicase is a substrate of the mitotic Cdc2 kinase.

  Cell cycle (Georgetown, Tex.) 20060801

• Cdk1/cyclin B-mediated phosphorylation stabilizes SREBP1 during mitosis.

  Cell cycle (Georgetown, Tex.) 20060801

• Structure and mechanism of the phosphotyrosyl phosphatase activator.

  Molecular cell 20060801

• Participation of superoxide in neutrophil activation and cytokine production.

  Biochimica et biophysica acta 20060801

• Revealing successive steps of deprotonation of L- phosphoserine through 13C and 31P chemical shielding tensor fingerprints.

  The journal of physical chemistry. A 20060727

• Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning.

  The Journal of biological chemistry 20060721

• Distinct signaling functions for Shc isoforms in the heart.

  The Journal of biological chemistry 20060721

• Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression.

  The Journal of biological chemistry 20060721

• Response of human mammary epithelial cells to DNA damage induced by 4-hydroxyequilenin: Lack of p53-mediated G1 arrest.

  Chemico-biological interactions 20060710

• Interleukin-1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62.

  FEBS letters 20060710

• Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger.

  Circulation 20060704

• Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.

  Pain 20060701

• Bovine brain phosphatidylserine attenuates scopolamine induced amnesia in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20060701

• Crystal structure of trehalose-6-phosphate phosphatase-related protein: biochemical and biological implications.

  Protein science : a publication of the Protein Society 20060701

• BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP.

  Genes & development 20060701

• Drosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without normal localization of kinetochore components.

  PLoS genetics 20060701

• Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway.

  Immunity 20060701

• Effects of phenyl saligenin phosphate on phosphorylation of pig brain tubulin in vitro.

  Environmental toxicology and pharmacology 20060701

• Simultaneous detection of tau phospho-epitopes with haptenylated antibodies.

  Neuroreport 20060626

• Polo-like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation.

  FEBS letters 20060626

• Small carboxyl-terminal domain phosphatase 2 attenuates androgen-dependent transcription.

  The EMBO journal 20060621

• The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

  The EMBO journal 20060621

• Intracerebroventricular injection of L-serine analogs and derivatives induces sedative and hypnotic effects under an acute stressful condition in neonatal chicks.

  Behavioural brain research 20060603

• Increased expression of LGI1 gene triggers growth inhibition and apoptosis of neuroblastoma cells.

  Journal of cellular physiology 20060601

• Detection of a tandem BRCT in Nbs1 and Xrs2 with functional implications in the DNA damage response.

  Bioinformatics (Oxford, England) 20060601

• Effect of pH on the structure and stability of Bacillus circulans ssp. alkalophilus phosphoserine aminotransferase: thermodynamic and crystallographic studies.

  Proteins 20060601

• Phosphorylation of the p34(cdc2) target site on goldfish germinal vesicle lamin B3 before oocyte maturation.

  European journal of cell biology 20060601

• Control of phage Bxb1 excision by a novel recombination directionality factor.

  PLoS biology 20060601

• Phosphorylation of endothelin converting enzyme-1 isoforms: relevance to subcellular localization.

  Experimental biology and medicine (Maywood, N.J.) 20060601

• The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability.

  Cell cycle (Georgetown, Tex.) 20060601

• Posttranslational phosphorylation of mutant p53 protein in tumor development.

  Medical molecular morphology 20060601

• Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans.

  PLoS genetics 20060601

• Alkaline Phosphatases : Structure, substrate specificity and functional relatedness to other members of a large superfamily of enzymes.

  Purinergic signalling 20060601

• Rec8 phosphorylation and recombination promote the step-wise loss of cohesins in meiosis.

  Nature 20060525

• Protein serine/threonine phosphatase-1 dephosphorylates p53 at Ser-15 and Ser-37 to modulate its transcriptional and apoptotic activities.

  Oncogene 20060518

• Characterization of yeast pyruvate kinase 1 as a protein kinase A substrate, and specificity of the phosphorylation site sequence in the whole protein.

  The Biochemical journal 20060515

• Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.

  The Biochemical journal 20060515

• Cardiac ryanodine receptor phosphorylation: target sites and functional consequences.

  The Biochemical journal 20060515

• Pigment epithelium-derived factor (PEDF) inhibits advanced glycation end product (AGE)-induced C-reactive protein expression in hepatoma cells by suppressing Rac-1 activation.

  FEBS letters 20060515

• The proinflammatory actions of angiotensin II are dependent on p65 phosphorylation by the IkappaB kinase complex.

  The Journal of biological chemistry 20060512

• Autophosphorylation of Akt at threonine 72 and serine 246. A potential mechanism of regulation of Akt kinase activity.

  The Journal of biological chemistry 20060512

• Hyperphosphorylation of tau induces local polyproline II helix.

  Biochemistry 20060502

• Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha.

  The Biochemical journal 20060501

• High-throughput fluorescence polarization assay to identify small molecule inhibitors of BRCT domains of breast cancer gene 1.

  Analytical biochemistry 20060501

• Metabolipidomics: profiling metabolism of glycerophospholipid species by stable isotopic precursors and tandem mass spectrometry.

  Analytical biochemistry 20060501

• Phosphorylation of paracellin-1 at Ser217 by protein kinase A is essential for localization in tight junctions.

  Journal of cell science 20060501

• 2-D DIGE analysis of butyrate-treated HCT-116 cells after enrichment with heparin affinity chromatography.

  Journal of proteome research 20060501

• Lipid specific activation of the murine P4-ATPase Atp8a1 (ATPase II).

  Biochemistry 20060425

• Characterization of a monoclonal antibody B1 that recognizes phosphorylated Ser-158 in the activation peptide region of human coagulation factor IX.

  The Journal of biological chemistry 20060407

• HSP induction mediates selective clearance of tau phosphorylated at proline-directed Ser/Thr sites but not KXGS (MARK) sites.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401

• Molecular verification of stereotactic radiotherapy in rats using ATMpS1981 immunofluorescence.

  Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060401

• p14ARF triggers G2 arrest through ERK-mediated Cdc25C phosphorylation, ubiquitination and proteasomal degradation.

  Cell cycle (Georgetown, Tex.) 20060401

• Conformational changes in protein loops and helices induced by post-translational phosphorylation.

  PLoS computational biology 20060401

• Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes.

  The Journal of biological chemistry 20060331

• The biochemical effect of Ser167 phosphorylation on Chlamydomonas reinhardtii centrin.

  Biochemical and biophysical research communications 20060331

• Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase.

  Molecular cell 20060317

• Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity.

  The Biochemical journal 20060301

• Downregulation of protein kinase B/Akt-1 mediates INS-1 insulinoma cell apoptosis induced by dominant-negative suppression of hepatocyte nuclear factor-1alpha function.

  Diabetologia 20060301

• Pattern-specific synaptic mechanisms in a multifunctional network. II. Intrinsic modulation by metabotropic glutamate receptors.

  Journal of neurophysiology 20060301

• Influence of calcium and phosphorus, lactose, and salt-to-moisture ratio on Cheddar cheese quality: pH buffering properties of cheese.

  Journal of dairy science 20060301

• CDK9 phosphorylates p53 on serine residues 33, 315 and 392.

  Cell cycle (Georgetown, Tex.) 20060301

• Borna disease virus blocks potentiation of presynaptic activity through inhibition of protein kinase C signaling.

  PLoS pathogens 20060301

• Nek1 shares structural and functional similarities with NIMA kinase.

  Biochimica et biophysica acta 20060301

• Nanofibers and their applications in tissue engineering.

  International journal of nanomedicine 20060301

• Phosphate group-driven fragmentation of multiply charged phosphopeptide anions. Improved recognition of peptides phosphorylated at serine, threonine, or tyrosine by negative ion electrospray tandem mass spectrometry.

  Analytical chemistry 20060215

• Structural mechanism of plant aquaporin gating.

  Nature 20060209

• Activation of the JAK-STAT signaling pathway in the rat basilar artery after subarachnoid hemorrhage.

  Brain research 20060209

• Antioxidative stress activity of oligophosphopeptides derived from hen egg yolk phosvitin in Caco-2 cells.

  Journal of agricultural and food chemistry 20060208

• Structure and desorption energetics of ultrathin D2O ice overlayers on serine- and serinephosphate-terminated self-assembled monolayers.

  The journal of physical chemistry. B 20060202

• Multiple forms of 22 kDa caveolin-1 alpha present in bovine lens cells could reflect variable palmitoylation.

  Experimental eye research 20060201

• AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine.

  Journal of molecular modeling 20060201

• Differential phosphorylation and dephosphorylation of beta2-adrenoceptor sites Ser262 and Ser355,356.

  British journal of pharmacology 20060201

• Kinase Cak1 functionally interacts with the PAF1 complex and phosphatase Ssu72 via kinases Ctk1 and Bur1.

  Molecular genetics and genomics : MGG 20060201

• Chemical derivatization of phosphoserine and phosphothreonine containing peptides to increase sensitivity for MALDI-based analysis and for selectivity of MS/MS analysis.

  Proteomics 20060201

• Mapping of the CCK, PSMC2, PSMC4, PSMD1, CPB1 and PSPH genes in cattle.

  Animal genetics 20060201

• Autophosphorylation of Ser66 on Xenopus Myt1 is a prerequisite for meiotic inactivation of Myt1.

  Cell cycle (Georgetown, Tex.) 20060201

• Structural basis of syndecan-4 phosphorylation as a molecular switch to regulate signaling.

  Journal of molecular biology 20060127

• Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125

• In vivo assessment of the significance of phosphorylation of the Arabidopsis chloroplast protein import receptor, atToc33.

  FEBS letters 20060123

• Vasodilator-stimulated phosphoprotein (VASP) is phosphorylated on Ser157 by protein kinase C-dependent and -independent mechanisms in thrombin-stimulated human platelets.

  The Biochemical journal 20060115

• Phosphorylation of HSF1 by MAPK-activated protein kinase 2 on serine 121, inhibits transcriptional activity and promotes HSP90 binding.

  The Journal of biological chemistry 20060113

• Hydrolysis of phosphatidylserine-exposing red blood cells by secretory phospholipase A2 generates lysophosphatidic acid and results in vascular dysfunction.

  The Journal of biological chemistry 20060113

• Lymphoma cells protected from apoptosis by dysregulated bcl-2 continue to bind annexin V in response to B-cell receptor engagement: a cautionary tale.

  Leukemia research 20060101

• Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways.

  Molecular and biochemical parasitology 20060101

• ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity.

  Cell cycle (Georgetown, Tex.) 20060101

• Effects of oestrogen on trigeminal ganglia in culture: implications for hormonal effects on migraine.

  Cephalalgia : an international journal of headache 20060101

• Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus.

  BMC microbiology 20060101

• UV photodissociation of phospho-seryl-containing peptides: laser stabilization of the phospho-seryl bond with multistage mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20060101

• Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL.

  BMC cell biology 20060101

• Protein kinases associated with the yeast phosphoproteome.

  BMC bioinformatics 20060101

• Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity.

  BMC biochemistry 20060101

• A phosphorylation map of the bovine papillomavirus E1 helicase.

  Virology journal 20060101

• The cell-specific activity of the estrogen receptor alpha may be fine-tuned by phosphorylation-induced structural gymnastics.

  Nuclear receptor signaling 20060101

• Cytometric assessment of histone H2AX phosphorylation: a reporter of DNA damage.

  Methods in molecular biology (Clifton, N.J.) 20060101

• Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis.

  BMC microbiology 20060101

• Nitric oxide agents impair insulin-mediated signal transduction in rat skeletal muscle.

  BMC biochemistry 20060101

• Treatment with amino acids in serine deficiency disorders.

  Journal of inherited metabolic disease 20060101

• Akt1 sequentially phosphorylates p27kip1 within a conserved but non-canonical region.

  Cell division 20060101

• Regulation of chromatin structure by histone H3S10 phosphorylation.

  Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 20060101

• Phosphoprotein analysis: from proteins to proteomes.

  Proteome science 20060101

• The fission yeast DNA structure checkpoint protein Rad26ATRIP/LCD1/UVSD accumulates in the cytoplasm following microtubule destabilization.

  BMC cell biology 20060101

• TLR2- and TLR4-dependent activation of STAT1 serine phosphorylation in murine macrophages is protein kinase C-delta-independent.

  Journal of endotoxin research 20060101

• Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data.

  Breast cancer research : BCR 20060101

• Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target.

  Journal of biomedicine & biotechnology 20060101

• Spindle checkpoint protein hMad2 and histone H3 phosphoserine 10 mitosis marker in pediatric solid tumors.

  Anticancer research 20060101

• Individual and combined effects of methamphetamine and ketamine on conditioned place preference and NR1 receptor phosphorylation in rats.

  Neuro-Signals 20060101

• The bacterial HPr kinase/phosphorylase: a new type of Ser/Thr kinase as antimicrobial target.

  Biochimica et biophysica acta 20051230

• Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin.

  Nature 20051222

• Manipulating the fragmentation patterns of phosphopeptides via gas-phase boron derivatization: determining phosphorylation sites in peptides with multiple serines.

  Journal of the American Society for Mass Spectrometry 20051201

• Peripheral hyperinsulinemia promotes tau phosphorylation in vivo.

  Diabetes 20051201

• Structural basis for phosphorylation-dependent signaling in the DNA-damage response.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20051201

• A universal assay for vitellogenin in fish mucus and plasma.

  Environmental toxicology and chemistry 20051201

• Phosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.

  The Biochemical journal 20051115

• HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding.

  The Journal of biological chemistry 20051111

• The phosphorylation of Ser318 of insulin receptor substrate 1 is not per se inhibitory in skeletal muscle cells but is necessary to trigger the attenuation of the insulin-stimulated signal.

  The Journal of biological chemistry 20051111

• Cross-talk between the two divergent insulin signaling pathways is revealed by the protein kinase B (Akt)-mediated phosphorylation of adapter protein APS on serine 588.

  The Journal of biological chemistry 20051111

• Attenuated phosphorylation of heat shock protein 27 correlates with tumor progression in patients with hepatocellular carcinoma.

  Biochemical and biophysical research communications 20051111

• Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower.

  Plant molecular biology 20051101

• Calcium/calmodulin-dependent protein kinase II (CaMKII), through NMDA receptors and L-Voltage-gated channels, modulates the serine phosphorylation of GluR6 during cerebral ischemia and early reperfusion period in rat hippocampus.

  Brain research. Molecular brain research 20051031

• Drug resistance in cancer.

  British journal of cancer 20051031

• Septin1, a new interaction partner for human serine/threonine kinase aurora-B.

  Biochemical and biophysical research communications 20051028

• A phosphorylation-dependent export structure in ROMK (Kir 1.1) channel overrides an endoplasmic reticulum localization signal.

  The Journal of biological chemistry 20051021

• Generation of protein kinase Ck1alpha mutants which discriminate between canonical and non-canonical substrates.

  The Biochemical journal 20051015

• Genetic and post-mortem mRNA analysis of the 14-3-3 genes that encode phosphoserine/threonine-binding regulatory proteins in schizophrenia and bipolar disorder.

  Schizophrenia research 20051015

• Calmodulin binds to the cytoplasmic domain of angiotensin-converting enzyme and regulates its phosphorylation and cleavage secretion.

  The Journal of biological chemistry 20051007

• Increases in intracellular calcium dephosphorylate histone H3 at serine 10 in human hepatoma cells: potential role of protein phosphatase 2A-protein kinase CbetaII complex.

  Journal of cellular physiology 20051001

• Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.

  Endocrinology 20051001

• Method development and measurements of endogenous serine/threonine Akt phosphorylation using capillary electrophoresis for systems biology.

  Electrophoresis 20051001

• Milk proteins and iron absorption: contrasting effects of different caseinophosphopeptides.

  Pediatric research 20051001

• Phospho-eNOS Ser-114 in human mesenchymal stem cells: constitutive phosphorylation, nuclear localization and upregulation during mitosis.

  European journal of cell biology 20051001

• Phosphorylation of the tau protein sequence 199-205 in the hippocampal CA3 region of Syrian hamsters in adulthood and during aging.

  Brain research 20050914

• Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans.

  The Journal of biological chemistry 20050909

• Lessons from nature: On the molecular recognition elements of the phosphoprotein binding-domains.

  Biotechnology and bioengineering 20050905

• Docosahexaenoic acid induces apoptosis in proliferating human endothelial cells.

  Journal of cellular physiology 20050901

• Two proline-rich peptides from pig (Sus scrofa) salivary glands generated by pre-secretory pathway underlying the action of a proteinase cleaving ProAla bonds.

  Peptides 20050901

• An AMBER/DYANA/MOLMOL phosphorylated amino acid library set and incorporation into NMR structure calculations.

  Journal of biomolecular NMR 20050901

• Retinoic acid as a modulator of the activity of protein kinase Calpha.

  Biochemistry 20050830

• Bradykinin preconditioning improves the profile of cell survival proteins and limits apoptosis after cardioplegic arrest.

  Circulation 20050830

• Keratin 8 phosphorylation by protein kinase C delta regulates shear stress-mediated disassembly of keratin intermediate filaments in alveolar epithelial cells.

  The Journal of biological chemistry 20050826

• Detection of amino acid and peptide phosphate protonation using Raman spectroscopy.

  Analytical biochemistry 20050815

• Gymnemic acids inhibit rabbit glyceraldehyde-3-phosphate dehydrogenase and induce a smearing of its electrophoretic band and dephosphorylation.

  FEBS letters 20050815

• Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in l-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0A resolution.

  Journal of molecular biology 20050812

• 14-3-3 proteins: a number of functions for a numbered protein.

  Science's STKE : signal transduction knowledge environment 20050809

• Phosphorylation of GRK1 and GRK7 by cAMP-dependent protein kinase attenuates their enzymatic activities.

  The Journal of biological chemistry 20050805

• Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-kappaB activation but not GSK3beta activity.

  Apoptosis : an international journal on programmed cell death 20050801

• Quantification by affinity perfusion chromatography of phosphorylated BRCAl and BRCA2 proteins from tumor cells after lycopene treatment.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050725

• Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding.

  Journal of the American Chemical Society 20050713

• Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713

• c-Src: bridging the gap between phosphorylation- and acidification-induced gap junction channel closure.

  Science's STKE : signal transduction knowledge environment 20050705

• The phosphorylation of CapZ-interacting protein (CapZIP) by stress-activated protein kinases triggers its dissociation from CapZ.

  The Biochemical journal 20050701

• The influence of lidocaine and verapamil on the proliferation, CD44 expression and apoptosis behavior of human chondrocytes.

  International journal of molecular medicine 20050701

• Detection and quantification of on-chip phosphorylated peptides by surface plasmon resonance imaging techniques using a phosphate capture molecule.

  Analytical chemistry 20050701

• Phosphorylation of p27(BBP)/eIF6 and its association with the cytoskeleton are developmentally regulated in Xenopus oogenesis.

  Cellular and molecular life sciences : CMLS 20050701

• Phosphoproteomic analysis with a solid-phase capture-release-tag approach.

  Chemistry & biology 20050701

• Differences in the association of p53 phosphorylated on serine 15 and key enzymes of homologous recombination.

  Oncogene 20050623

• Phosphorylation of Grb10 by mitogen-activated protein kinase: identification of Ser150 and Ser476 of human Grb10zeta as major phosphorylation sites.

  Biochemistry 20050621

• Silencing of p21-activated kinase attenuates vimentin phosphorylation on Ser-56 and reorientation of the vimentin network during stimulation of smooth muscle cells by 5-hydroxytryptamine.

  The Biochemical journal 20050615

• DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.

  Biochemistry 20050614

• Phosphorylation of BAD at Ser-128 during mitosis and paclitaxel-induced apoptosis.

  FEBS letters 20050606

• Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals.

  FEBS letters 20050606

• Proteomic analysis of primary cultures of human adipose-derived stem cells: modulation by Adipogenesis.

  Molecular & cellular proteomics : MCP 20050601

• Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

  Cell death and differentiation 20050601

• Lipid binding region (2303-2332) is involved in aggregation of recombinant human FVIII (rFVIII).

  Journal of pharmaceutical sciences 20050601

• Strain relief at the active site of phosphoserine aminotransferase induced by radiation damage.

  Protein science : a publication of the Protein Society 20050601

• Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly.

  The EMBO journal 20050601

• theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability.

  The Journal of pharmacology and experimental therapeutics 20050601

• Extract of gum resins of Boswellia serrata L. inhibits lipopolysaccharide induced nitric oxide production in rat macrophages along with hypolipidemic property.

  Indian journal of experimental biology 20050601

• Src kinase regulation by phosphorylation and dephosphorylation.

  Biochemical and biophysical research communications 20050527

• Polo kinase links the stress pathway to cell cycle control and tip growth in fission yeast.

  Nature 20050526

• A phosphoserine-lysine salt bridge within an alpha-helical peptide, the strongest alpha-helix side-chain interaction measured to date.

  Biochemistry 20050524

• Genetic basis of phenotypic plasticity for predator-induced morphological defenses in anuran tadpole, Rana pirica, using cDNA subtraction and microarray analysis.

  Biochemical and biophysical research communications 20050520

• alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells.

  Experimental cell research 20050515

• Association of DNA methylation of phosphoserine aminotransferase with response to endocrine therapy in patients with recurrent breast cancer.

  Cancer research 20050515

• Lower inhibitor development in hemophilia A mice following administration of recombinant factor VIII-O-phospho-L-serine complex.

  The Journal of biological chemistry 20050506

• Acidic residues emulate a phosphorylation switch to enhance the activity of rat hepatic neutral cytosolic cholesterol esterase.

  Biochimica et biophysica acta 20050501

• 14-3-3sigma expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20050501

• Phosphorylation-specific prolyl isomerization: is there an underlying theme?

  Nature cell biology 20050501

• Localisation of high acid phosphotyrosine phosphatase activity in afferent arterioles and glomeruli of human kidney.

  Journal of molecular histology 20050501

• Identification of the regions of PECAM-1 involved in beta- and gamma-catenin associations.

  Biochemical and biophysical research communications 20050422

• Size-selected (2-10 nm) gold nanoparticles for matrix assisted laser desorption ionization of peptides.

  Journal of the American Chemical Society 20050420

• Expression of p16INK4A variants in senescent human fibroblasts independent of protein phosphorylation.

  Journal of cellular biochemistry 20050415

• Rapid enrichment and analysis of yeast phosphoproteins using affinity chromatography, 2D-PAGE and peptide mass fingerprinting.

  Yeast (Chichester, England) 20050415

• Binding mode and transcriptional activation potential of high affinity ligands for the CBP KIX domain.

  Journal of the American Chemical Society 20050406

• Modulation of insulin signalling by insulin sensitizers.

  Biochemical Society transactions 20050401

• 14-3-3 proteins--an update.

  Cell research 20050401

• RNA-dependent cysteine biosynthesis in archaea.

  Science (New York, N.Y.) 20050325

• Competition between intramolecular hydrogen bonds and solvation in phosphorylated peptides: simulations with explicit and implicit solvent.

  The journal of physical chemistry. B 20050324

• Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates.

  Bioorganic & medicinal chemistry letters 20050315

• Regulation of plant symbiosis receptor kinase through serine and threonine phosphorylation.

  The Journal of biological chemistry 20050311

• Regulation of zipper-interacting protein kinase activity in vitro and in vivo by multisite phosphorylation.

  The Journal of biological chemistry 20050311

• Consequences of lysine 72 mutation on the phosphorylation and activation state of cAMP-dependent kinase.

  The Journal of biological chemistry 20050311

• Activation of mu-opioid receptors transfers control of Galpha subunits to the regulator of G-protein signaling RGS9-2: role in receptor desensitization.

  The Journal of biological chemistry 20050311

• Evolution of a microbial acetyltransferase for modification of glyphosate: a novel tolerance strategy.

  Pest management science 20050301

• Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway.

  Diabetologia 20050301

• Endothelial cell activation of the smooth muscle cell phosphoinositide 3-kinase/Akt pathway promotes differentiation.

  Journal of vascular surgery 20050301

• Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1.

  FEBS letters 20050227

• Serum/glucocorticoid-inducible kinase can phosphorylate the cyclic AMP response element binding protein, CREB.

  FEBS letters 20050227

• A comparative study of the effect of the antineoplastic ether lipid 1-O-octadecyl-2-O-methyl-glycero-3-phosphocholine and some homologous compounds on PKC alpha and PKC epsilon.

  Biochimica et biophysica acta 20050221

• Phosphorylation of p27Kip1 at Thr-157 interferes with its association with importin alpha during G1 and prevents nuclear re-entry.

  The Journal of biological chemistry 20050218

• SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway.

  Molecular cell 20050218

• Linking Smads and transcriptional activation.

  The Biochemical journal 20050215

• In vitro phosphorylation by cAMP-dependent protein kinase up-regulates recombinant Saccharomyces cerevisiae mannosylphosphodolichol synthase.

  The Journal of biological chemistry 20050211

• Effect of phosphorylation of ovalbumin on adsorption by aluminum-containing adjuvants and elution upon exposure to interstitial fluid.

  Vaccine 20050210

• Akt mediates the cross-talk between beta-adrenergic and insulin receptors in neonatal cardiomyocytes.

  Circulation research 20050204

• Another role for the celebrity: Akt and insulin resistance.

  Circulation research 20050204

• Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202

• Laminin-1 is phosphorylated by ecto-protein kinases of monocytes.

  The international journal of biochemistry & cell biology 20050201

• The Drosophila protein kinase LK6 is regulated by ERK and phosphorylates the eukaryotic initiation factor eIF4E in vivo.

  The Biochemical journal 20050201

• Transducible heat shock protein 20 (HSP20) phosphopeptide alters cytoskeletal dynamics.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201

• Preferential phosphorylation of R-domain Serine 768 dampens activation of CFTR channels by PKA.

  The Journal of general physiology 20050201

• Phosphoserines on maize CENTROMERIC HISTONE H3 and histone H3 demarcate the centromere and pericentromere during chromosome segregation.

  The Plant cell 20050201

• Dynamic distribution of Ser-10 phosphorylated histone H3 in cytoplasm of MCF-7 and CHO cells during mitosis.

  Cell research 20050201

• Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease.

  The Journal of biological chemistry 20050121

• Characterization of a plant, tyrosine-specific phosphatase of the aspartyl class.

  Biochemistry 20050118

• Diazinon alters sperm chromatin structure in mice by phosphorylating nuclear protamines.

  Toxicology and applied pharmacology 20050115

• Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors.

  The Journal of biological chemistry 20050114

• Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR).

  The Journal of biological chemistry 20050114

• Role of serine 10 phosphorylation in p27 stabilization revealed by analysis of p27 knock-in mice harboring a serine 10 mutation.

  The Journal of biological chemistry 20050114

• c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.

  The Journal of biological chemistry 20050114

• Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase.

  Biochemical and biophysical research communications 20050114

• Purification and partial characterization of an acid phosphatase from Spirodela oligorrhiza and its affinity for selected organophosphate pesticides.

  Journal of agricultural and food chemistry 20050112

• Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.

  Molecular endocrinology (Baltimore, Md.) 20050101

• 14-3-3 regulation of cell spreading and migration requires a functional amphipathic groove.

  Journal of cellular physiology 20050101

• Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects.

  Molecular pharmacology 20050101

• Chronophin, a novel HAD-type serine protein phosphatase, regulates cofilin-dependent actin dynamics.

  Nature cell biology 20050101

• Enzyme adaptation to alkaline pH: atomic resolution (1.08 A) structure of phosphoserine aminotransferase from Bacillus alcalophilus.

  Protein science : a publication of the Protein Society 20050101

• A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C.

  Journal of molecular and cellular cardiology 20050101

• Interaction between mGluR8 and calcium channels in photoreceptors is sensitive to pertussis toxin and occurs via G protein betagamma subunit signaling.

  Investigative ophthalmology & visual science 20050101

• Roscovitine-induced up-regulation of p53AIP1 protein precedes the onset of apoptosis in human MCF-7 breast cancer cells.

  Molecular cancer therapeutics 20050101

• Novel phosphorylation of histone H3 at threonine 11 that temporally correlates with condensation of mitotic and meiotic chromosomes in plant cells.

  Cytogenetic and genome research 20050101

• A comprehensive update of the sequence and structure classification of kinases.

  BMC structural biology 20050101

• Iodoacetamide-alkylated methionine can mimic neutral loss of phosphoric acid from phosphopeptides as exemplified by nano-electrospray ionization quadrupole time-of-flight parent ion scanning.

  Rapid communications in mass spectrometry : RCM 20050101

• Effects of naltrexone on lipopolysaccharide-induced sepsis in rats.

  Journal of biomedical science 20050101

• High-throughput kinase assays with protein substrates using fluorescent polymer superquenching.

  BMC biotechnology 20050101

• 14-3-3 protein signaling in development and growth factor responses.

  Current topics in developmental biology 20050101

• An inactivated nuclease-like domain in RecC with novel function: implications for evolution.

  BMC structural biology 20050101

• Advantage of a baculovirus expression system for protein-protein interaction studies. Involvement of posttranslational phosphorylation in the interaction between wt p53 protein and poly(ADP-ribose) polymerase-1.

  Acta biochimica Polonica 20050101

• Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level.

  Neuropharmacology 20050101

• A simplified immunoprecipitation method for quantitatively measuring antibody responses in clinical sera samples by using mammalian-produced Renilla luciferase-antigen fusion proteins.

  BMC biotechnology 20050101

• Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation.

  Molecular pain 20050101

• Phosphoproteomics: new insights into cellular signaling.

  Genome biology 20050101

• Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer.

  Breast cancer research : BCR 20050101

• Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease.

  Journal of neuroinflammation 20050101

• Protein kinase activity is associated with CD63 in melanoma cells.

  Journal of translational medicine 20050101

• Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

  Virology journal 20050101

• A novel mass spectrometry-based assay for GSK-3beta activity.

  BMC biochemistry 20050101

• Control of isocitrate dehydrogenase catalytic activity by protein phosphorylation in Escherichia coli.

  Journal of molecular microbiology and biotechnology 20050101

• Phosphorylation of RanGAP1 stabilizes its interaction with Ran and RanBP1.

  Cell structure and function 20050101

• [Huntington's disease: intracellular signaling pathways and neuronal death].

  Journal de la Societe de biologie 20050101

• Post-translational modification(s) and cell distribution of Streptomyces aureofaciens translation elongation factor Tu overproduced in Escherichia coli.

  Folia microbiologica 20050101

• Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.

  The Biochemical journal 20041215

• Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.

  The Biochemical journal 20041215

• Beta-elimination coupled with tandem mass spectrometry for the identification of in vivo and in vitro phosphorylation sites in maize dehydrin DHN1 protein.

  Biochemistry 20041214

• Accumulation of inhibitory kappaB-alpha as a mechanism contributing to the anti-inflammatory effects of surfactant protein-A.

  American journal of respiratory cell and molecular biology 20041201

• Anthelmintic efficacy of genistein, the active principle of Flemingia vestita (Fabaceae): alterations in the free amino acid pool and ammonia levels in the fluke, Fasciolopsis buski.

  Parasitology international 20041201

• Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere.

  Journal of the American Chemical Society 20041201

• The tube cement of Phragmatopoma californica: a solid foam.

  The Journal of experimental biology 20041201

• Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function.

  Circulation research 20041126

• Another new kinase targets troponin I.

  Circulation research 20041126

• Epitope mapping of the phosphorylation motif of the HIV-1 protein Vpu bound to the selective monoclonal antibody using TRNOESY and STD NMR spectroscopy.

  Biochemistry 20041123

• Interactions between extracellular signal-regulated protein kinase 1, 14-3-3epsilon, and heat shock factor 1 during stress.

  The Journal of biological chemistry 20041119

• Regulation of the NMDA receptor complex and trafficking by activity-dependent phosphorylation of the NR2B subunit PDZ ligand.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110

• Photocontrol of Smad2, a multiphosphorylated cell-signaling protein, through caging of activating phosphoserines.

  Angewandte Chemie (International ed. in English) 20041105

• Effects of ovarian steroids and raloxifene on proteins that synthesize, transport, and degrade serotonin in the raphe region of macaques.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20041101

• Characterization of a monoclonal antibody, HTA28, recognizing a histone H3 phosphorylation site as a useful marker of M-phase cells.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20041101

• Activated polymorphonuclear neutrophils disseminate anti-inflammatory microparticles by ectocytosis.

  Blood 20041015

• Phosphorylation of androgen receptor isoforms.

  The Biochemical journal 20041015

• Integrin-linked kinase regulates the nuclear entry of the c-Jun coactivator alpha-NAC and its coactivation potency.

  The Journal of biological chemistry 20041015

• Semiconductor-encapsulated peptide-amphiphile nanofibers.

  Journal of the American Chemical Society 20041013

• Synergistic activation of CREB-mediated transcription by forskolin and phorbol ester requires PKC and depends on the glutamine-rich Q2 transactivation domain.

  Cellular signalling 20041001

• PTH and phospholipase A2 in the aging process of intestinal cells.

  Journal of cellular biochemistry 20041001

• Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath).

  PLoS biology 20041001

• Disruption of protein-membrane binding and identification of small-molecule inhibitors of coagulation factor VIII.

  Chemistry & biology 20041001

• [Nobel genes improve accuracy in detection of peritoneal micro-metastasis of gastric cancer to decide indication for chemotherapy].

  Gan to kagaku ryoho. Cancer & chemotherapy 20041001

• Baculovirus-mediated expression and isolation of human ribosomal phosphoprotein P0 carrying a GST-tag in a functional state.

  Biochemical and biophysical research communications 20040924

• Akt/protein kinase B and endothelial nitric oxide synthase mediate muscular neovascularization induced by tissue kallikrein gene transfer.

  Circulation 20040921

• The plasma membrane translocation of diacylglycerol kinase delta1 is negatively regulated by conventional protein kinase C-dependent phosphorylation at Ser-22 and Ser-26 within the pleckstrin homology domain.

  The Biochemical journal 20040915

• Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity.

  Archives of biochemistry and biophysics 20040915

• cAMP-response element-binding protein mediates tumor necrosis factor-alpha-induced vascular smooth muscle cell migration.

  Arteriosclerosis, thrombosis, and vascular biology 20040901

• Characterization of protein tyrosine phosphatase activity in rat liver microsomes: suppressive effect of endogenous regucalcin in transgenic rats.

  International journal of molecular medicine 20040901

• Thrombin and histamine stimulate endothelial nitric-oxide synthase phosphorylation at Ser1177 via an AMPK mediated pathway independent of PI3K-Akt.

  FEBS letters 20040827

• Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells.

  Biochemical and biophysical research communications 20040820

• Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375.

  The EMBO journal 20040818

• Phosphorylated alpha-synuclein in normal mouse brain.

  FEBS letters 20040813

• Identification of novel phosphorylation sites on postsynaptic density proteins.

  Biochemical and biophysical research communications 20040813

• Changes in AMPA receptor phosphorylation in the rostral ventromedial medulla after inflammatory hyperalgesia in rats.

  Neuroscience letters 20040812

• c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes.

  The Journal of biological chemistry 20040806

• Phosphorylation of septin 3 on Ser-91 by cGMP-dependent protein kinase-I in nerve terminals.

  The Biochemical journal 20040801

• Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes.

  Molecular endocrinology (Baltimore, Md.) 20040801

• Vasodilator-stimulated phosphoprotein regulates proliferation and growth inhibition by nitric oxide in vascular smooth muscle cells.

  Arteriosclerosis, thrombosis, and vascular biology 20040801

• Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.

  Arteriosclerosis, thrombosis, and vascular biology 20040801

• L-CCG-I activates group III metabotropic glutamate receptors in the hippocampal CA3 region.

  Neuropharmacology 20040801

• Overexpression of tau leads to the stimulation of neurite outgrowth, the activation of caspase 3 activity, and accumulation and phosphorylation of tau in neuroblastoma cells on cAMP treatment.

  Neuroscience research 20040801

• Evolutionary trace analysis of the alpha-D-phosphohexomutase superfamily.

  Protein science : a publication of the Protein Society 20040801

• Metabotropic glutamate receptors modulate ischemia-induced GABA release in mouse hippocampal slices.

  Neurochemical research 20040801

• Caged phosphopeptides reveal a temporal role for 14-3-3 in G1 arrest and S-phase checkpoint function.

  Nature biotechnology 20040801

• Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry.

  Analytical chemistry 20040801

• Regulation of dopamine D-receptor activation in vivo by protein phosphatase 2B (calcineurin).

  Journal of neurochemistry 20040801

• How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase.

  European journal of biochemistry 20040801

• Characterization of dynamic and steady-state protein phosphorylation using a fluorescent phosphoprotein gel stain and mass spectrometry.

  Electrophoresis 20040801

• Chemical segregation and reduction of Raman background interference using drop coating deposition.

  Applied spectroscopy 20040801

• Mitogen-activated protein kinases mediate the oxidative burst and saponin synthesis induced by chitosan in cell cultures of Panax ginseng.

  Science in China. Series C, Life sciences 20040801

• Dominant negative 14-3-3 promotes cardiomyocyte apoptosis in early stage of type I diabetes mellitus through activation of JNK.

  Biochemical and biophysical research communications 20040730

• Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site.

  FEBS letters 20040730

• Ability of alphas-Casein to suppress the heat aggregation of ovotransferrin.

  Journal of agricultural and food chemistry 20040728

• Parathyroid-hormone-related protein as a regulator of pRb and the cell cycle in arterial smooth muscle.

  Circulation 20040713

• 14-3-3 proteins: a number of functions for a numbered protein.

  Science's STKE : signal transduction knowledge environment 20040713

• Identification of DNA 3'-phosphatase active site residues and their differential role in DNA binding, Mg2+ coordination, and catalysis.

  Biochemistry 20040706

• Malonyl-CoA decarboxylase (MCD) is differentially regulated in subcellular compartments by 5'AMP-activated protein kinase (AMPK). Studies using H9c2 cells overexpressing MCD and AMPK by adenoviral gene transfer technique.

  European journal of biochemistry 20040701

• A small heat shock protein from Artemia franciscana is phosphorylated at serine 50.

  Biochimica et biophysica acta 20040701

• Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains.

  Structure (London, England : 1993) 20040701

• A plasmid-encoded class 1 integron carrying sat, a putative phosphoserine phosphatase gene and aadA2 from enterotoxigenic Escherichia coli O159 isolated in Japan.

  FEMS microbiology letters 20040615

• Protein phosphatase 1, but not protein phosphatase 2A, dephosphorylates DNA-damaging stress-induced phospho-serine 15 of p53.

  FEBS letters 20040604

• Mechanism and importance of post-translational regulation of nitrate reductase.

  Journal of experimental botany 20040601

• Regulation of haematopoiesis by growth factors - emerging insights and therapies.

  Expert opinion on biological therapy 20040601

• Identification of possible phosducins in the ciliate Blepharisma japonicum.

  Protist 20040601

• Downregulation of beta-catenin by p53 involves changes in the rate of beta-catenin phosphorylation and Axin dynamics.

  Oncogene 20040527

• Binding of RNA to p53 regulates its oligomerization and DNA-binding activity.

  Oncogene 20040527

• Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

  Oncogene 20040527

• Semisynthesis of phosphovariants of Smad2 reveals a substrate preference of the activated T beta RI kinase.

  Biochemistry 20040518

• In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.

  Biochemistry 20040518

• Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2.

  The Biochemical journal 20040515

• Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils.

  The Journal of biological chemistry 20040514

• Role of the cyclic AMP-dependent protein kinase in homologous resensitization of the beta1-adrenergic receptor.

  The Journal of biological chemistry 20040514

• Leukemia inhibitory factor activates cardiac L-Type Ca2+ channels via phosphorylation of serine 1829 in the rabbit Cav1.2 subunit.

  Circulation research 20040514

• Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.

  Circulation research 20040514

• TAF1 activates transcription by phosphorylation of serine 33 in histone H2B.

  Science (New York, N.Y.) 20040514

• Influence of electric charge variation at residues 209 and 159 on the interaction of eIF4E with the mRNA 5' terminus.

  Biochemistry 20040511

• Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.

  The Biochemical journal 20040501

• Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20040501

• Sildenafil-induced vasorelaxation is associated with increases in the phosphorylation of the heat shock-related protein 20 (HSP20).

  The Journal of surgical research 20040501

• Structural and stability effects of phosphorylation: Localized structural changes in phenylalanine hydroxylase.

  Protein science : a publication of the Protein Society 20040501

• Stabilization of discordant helices in amyloid fibril-forming proteins.

  Protein science : a publication of the Protein Society 20040501

• The infant mouse as a in vivo model for the detection and study of DNA damage-induced changes in the liver.

  Molecular carcinogenesis 20040501

• Identifying protein kinase substrates: hunting for the organ-grinder's monkeys.

  Trends in biochemical sciences 20040501

• Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases.

  The EMBO journal 20040421

• JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins.

  The EMBO journal 20040421

• Phosphorylation of eukaryotic translation initiation factor 2Bepsilon by glycogen synthase kinase-3beta regulates beta-adrenergic cardiac myocyte hypertrophy.

  Circulation research 20040416

• Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation.

  Oncogene 20040415

• Master of all things phosphorylated.

  The Biochemical journal 20040415

• Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor.

  Circulation research 20040402

• Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.

  The Biochemical journal 20040401

• Changes in the vascular beta-adrenoceptor-activated signalling pathway in 2Kidney-1Clip hypertensive rats.

  British journal of pharmacology 20040401

• Comparative expression of NFkappaB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies.

  Pigment cell research 20040401

• Phosphorylated amino acids: model compounds for solid-state 31P NMR spectroscopic studies of proteins.

  Magnetic resonance in chemistry : MRC 20040401

• Prolonged incubation in PUGNAc results in increased protein O-Linked glycosylation and insulin resistance in rat skeletal muscle.

  Diabetes 20040401

• Pinning down cell signaling, cancer and Alzheimer's disease.

  Trends in biochemical sciences 20040401

• Phosphoserine--a convenient compound for modification of calcium phosphate bone cement collagen composites.

  Journal of materials science. Materials in medicine 20040401

• The thrH gene product of Pseudomonas aeruginosa is a dual activity enzyme with a novel phosphoserine:homoserine phosphotransferase activity.

  The Journal of biological chemistry 20040326

• Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6).

  Circulation research 20040305

• Haematopoietic protein tyrosine phosphatase (HePTP) phosphorylation by cAMP-dependent protein kinase in T-cells: dynamics and subcellular location.

  The Biochemical journal 20040301

• Arsenic trioxide and paclitaxel induce apoptosis by different mechanisms.

  Cell cycle (Georgetown, Tex.) 20040301

• Inhibition of cdk1 by alsterpaullone and thioflavopiridol correlates with increased transit time from mid G2 through prophase.

  Cell cycle (Georgetown, Tex.) 20040301

• Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.

  Molecular & cellular proteomics : MCP 20040301

• Protein signal assignments using specific labeling and cell-free synthesis.

  Journal of biomolecular NMR 20040301

• Identification of calcium-inducible genes in primary keratinocytes using suppression-subtractive hybridization.

  Experimental dermatology 20040301

• Insulin resistance and GLUT-4 glucose transporter in adipocytes from hypertensive rats.

  Metabolism: clinical and experimental 20040301

• Proteomic analysis on symbiotic differentiation of mitochondria in soybean nodules.

  Plant & cell physiology 20040301

• On the evolution of erythrocyte programmed cell death: apoptosis of Rana esculenta nucleated red blood cells involves cysteine proteinase activation and mitochondrion permeabilization.

  Biochimie 20040301

• Tumor necrosis factor alpha inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis.

  The Journal of biological chemistry 20040227

• Phospho-serine-118 estrogen receptor-alpha detection in human breast tumors in vivo.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040215

• [Ser2]- and [SerP2] incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo.

  The Journal of biological chemistry 20040206

• Reactions of serine palmitoyltransferase with serine and molecular mechanisms of the actions of serine derivatives as inhibitors.

  Biochemistry 20040203

• The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-kappaB and induction of bcl-2.

  Blood 20040201

• Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons.

  Cell death and differentiation 20040201

• Mutations responsible for 3-phosphoserine phosphatase deficiency.

  European journal of human genetics : EJHG 20040201

• A zinc-binding dual-specificity YVH1 phosphatase in the malaria parasite, Plasmodium falciparum, and its interaction with the nuclear protein, pescadillo.

  Molecular and biochemical parasitology 20040201

• Suppressive effect of regucalcin on protein phosphatase activity in the heart cytosol of normal and regucalcin transgenic rats.

  International journal of molecular medicine 20040201

• Molecular cloning and characterization of two different cDNAs encoding the molecular chaperone Hsp90 in the oomycete Achlya ambisexualis.

  Fungal genetics and biology : FG & B 20040201

• Expression and secretion of functional recombinant scu-PA:AV in insect cell using signal peptides.

  Protein and peptide letters 20040201

• The charged milieu: a major player in fertilization reactions.

  Acta histochemica 20040201

• Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling.

  Annales d'endocrinologie 20040201

• Unique in vivo modifications of coagulation factor V produce a physically and functionally distinct platelet-derived cofactor: characterization of purified platelet-derived factor V/Va.

  The Journal of biological chemistry 20040123

• Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance.

  The Journal of biological chemistry 20040116

• SH2-B is a positive regulator of nerve growth factor-mediated activation of the Akt/Forkhead pathway in PC12 cells.

  The Journal of biological chemistry 20040102

• Activation of group III metabotropic glutamate receptors in selected regions of the basal ganglia alleviates akinesia in the reserpine-treated rat.

  British journal of pharmacology 20040101

• Cyclin-dependent kinase 11p110 and casein kinase 2 (CK2) inhibit the interaction between tyrosine hydroxylase and 14-3-3.

  Journal of neurochemistry 20040101

• Ceramide content is increased in skeletal muscle from obese insulin-resistant humans.

  Diabetes 20040101

• D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a.

  EMBO reports 20040101

• Characterization of agonist stimulation of cAMP-dependent protein kinase and G protein-coupled receptor kinase phosphorylation of the beta2-adrenergic receptor using phosphoserine-specific antibodies.

  Molecular pharmacology 20040101

• Cell cycle arrest by monochloramine through the oxidation of retinoblastoma protein.

  Free radical biology & medicine 20040101

• TIAF1 and p53 functionally interact in mediating apoptosis and silencing of TIAF1 abolishes nuclear translocation of serine 15-phosphorylated p53.

  DNA and cell biology 20040101

• The use of in vitro peptide-library screens in the analysis of phosphoserine/threonine-binding domain structure and function.

  Annual review of biophysics and biomolecular structure 20040101

• Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1.

  BMC cell biology 20040101

• Combination of L-3-phosphoserine phosphatase and CEA using real-time RT-PCR improves accuracy in detection of peritoneal micrometastasis of gastric cancer.

  Anticancer research 20040101

• Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3.

  BMC cell biology 20040101

• Phospho.ELM: a database of experimentally verified phosphorylation sites in eukaryotic proteins.

  BMC bioinformatics 20040101

• Analyzing the regulation and function of ATM.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Changes in sperm glycogen synthase kinase-3 serine phosphorylation and activity accompany motility initiation and stimulation.

  Journal of andrology 20040101

• Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

  BMC biology 20040101

• The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.

  Arthritis research & therapy 20040101

• The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases.

  Genome biology 20040101

• Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction.

  Reproductive biology and endocrinology : RB&E 20040101

• Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry.

  Journal of proteome research 20040101

• Talin distribution during the differentiation of satellite cells isolated from rat skeletal muscle.

  Cellular & molecular biology letters 20040101

• Serine metabolism in Lactobacillus plantarum.

  International journal of food microbiology 20031231

• Phosphopeptide binding specificities of BRCA1 COOH-terminal (BRCT) domains.

  The Journal of biological chemistry 20031226

• Protein phosphatase 1 binds to phospho-Ser-1394 of the macrophage-stimulating protein receptor.

  The Biochemical journal 20031215

• Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides.

  Analytical chemistry 20031215

• SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase.

  Genes & development 20031215

• The biosynthesis of cysteine and homocysteine in Methanococcus jannaschii.

  Biochimica et biophysica acta 20031205

• Changes in JNK1 activity in the frog (Rana esculenta) testis.

  Molecular reproduction and development 20031201

• CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.

  Nature structural biology 20031201

• Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats.

  Diabetologia 20031201

• Expression, purification, crystallization and preliminary crystallographic analysis of phosphoserine aminotransferase from Bacillus alcalophilus.

  Acta crystallographica. Section D, Biological crystallography 20031201

• Pten dose dictates cancer progression in the prostate.

  PLoS biology 20031201

• Membrane-associated serine/threonine protein phosphatase in endometrial cancer.

  American journal of obstetrics and gynecology 20031201

• Dependence of the interfacial behavior of beta-casein on phosphoserine residues.

  Journal of dairy science 20031201

• Comparative modelling of human PHOSPHO1 reveals a new group of phosphatases within the haloacid dehalogenase superfamily.

  Protein engineering 20031201

• Reversible oxidation of the active site cysteine of peroxiredoxins to cysteine sulfinic acid. Immunoblot detection with antibodies specific for the hyperoxidized cysteine-containing sequence.

  The Journal of biological chemistry 20031128

• Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro.

  Biochimica et biophysica acta 20031120

• Influence of immobilization stress on the expression and phosphatase activity of protein phosphatase 2A in the rat brain.

  Biological psychiatry 20031115

• Differentiation between acetylcholinesterase and the organophosphate-inhibited form using antibodies and the correlation of antibody recognition with reactivation mechanism and rate.

  The Journal of biological chemistry 20031114

• Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.

  Cell 20031114

• Silent cleanup of very early apoptotic cells by macrophages.

  Journal of immunology (Baltimore, Md. : 1950) 20031101

• MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632.

  Diabetologia 20031101

• The orientation of mycobacteriophage Bxb1 integration is solely dependent on the central dinucleotide of attP and attB.

  Molecular cell 20031101

• Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.

  Biochemistry 20031028

• BRCT repeats as phosphopeptide-binding modules involved in protein targeting.

  Science (New York, N.Y.) 20031024

• The BRCT domain is a phospho-protein binding domain.

  Science (New York, N.Y.) 20031024

• Bradykinin B1 receptor stimulates the proximal tubule Na(+)-ATPase activity through protein kinase C pathway.

  Regulatory peptides 20031015

• Phosphoprotein isotope-coded solid-phase tag approach for enrichment and quantitative analysis of phosphopeptides from complex mixtures.

  Analytical chemistry 20031015

• Phosphorylation of insulin receptor substrate-1 serine 307 correlates with JNK activity in atrophic skeletal muscle.

  FEBS letters 20031009

• Rim, a component of the presynaptic active zone and modulator of exocytosis, binds 14-3-3 through its N terminus.

  The Journal of biological chemistry 20031003

• Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase.

  Free radical biology & medicine 20031001

• Plasma amino acids in ecstasy users.

  Neuro endocrinology letters 20031001

• Archaeosomes varying in lipid composition differ in receptor-mediated endocytosis and differentially adjuvant immune responses to entrapped antigen.

  Archaea (Vancouver, B.C.) 20031001

• The dimeric versus monomeric status of 14-3-3zeta is controlled by phosphorylation of Ser58 at the dimer interface.

  The Journal of biological chemistry 20030919

• A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.

  Science (New York, N.Y.) 20030919

• Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.

  The EMBO journal 20030915

• Identification of a functionally critical protein kinase C phosphorylation residue of cardiac troponin T.

  The Journal of biological chemistry 20030912

• Characterization of protein kinase A-mediated phosphorylation of ezrin in gastric parietal cell activation.

  The Journal of biological chemistry 20030912

• Prolonged survival of the phosphorylated form of rhodopsin during dark adaptation of Royal College Surgeons rat.

  FEBS letters 20030911

• A novel O-phospho-L-serine sulfhydrylation reaction catalyzed by O-acetylserine sulfhydrylase from Aeropyrum pernix K1.

  FEBS letters 20030911

• Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: termination of CNS autoimmune inflammation and modulation by interferon-beta.

  Glia 20030901

• Phosphospecific proteolysis for mapping sites of protein phosphorylation.

  Nature biotechnology 20030901

• Inhibition of interferon gamma signaling by the short chain fatty acid butyrate.

  Molecular cancer research : MCR 20030901

• Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins.

  The Journal of biological chemistry 20030829

• Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis.

  Oncogene 20030828

• Fluorescent caged phosphoserine peptides as probes to investigate phosphorylation-dependent protein associations.

  Journal of the American Chemical Society 20030827

• Glutamate metabotropic receptors as targets for drug therapy in epilepsy.

  European journal of pharmacology 20030822

• Phosphorylation regulates the interaction and complex formation between wt p53 protein and PARP-1.

  Journal of cellular biochemistry 20030815

• Activation of tyrosine hydroxylase by intermittent hypoxia: involvement of serine phosphorylation.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030801

• Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.

  The Journal of biological chemistry 20030801

• Molecular mechanism for growth suppression of human hepatocellular carcinoma cells by acyclic retinoid.

  Carcinogenesis 20030801

• Synthesis of a radioactive thiol reagent, 1-S-[3H]carboxymethyl-dithiothreitol: identification of the phosphorylation sites by N-terminal peptide sequencing and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

  Analytical biochemistry 20030801

• Novel effect of N-palmitoyl-L-serine phosphoric acid on cytosolic Ca2+ levels in human osteoblasts.

  Pharmacology & toxicology 20030801

• Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

  Nature 20030731

• Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis.

  The Biochemical journal 20030701

• EGF receptor-mediated, c-Src-dependent, activation of Stat5b is downregulated in mitogenically responsive hepatocytes.

  Journal of cellular physiology 20030701

• Activation of protein kinase C delta by IFN-gamma.

  Journal of immunology (Baltimore, Md. : 1950) 20030701

• Global quantitative phosphoprotein analysis using Multiplexed Proteomics technology.

  Proteomics 20030701

• Oscillating fluid flow regulates gap junction communication in osteocytic MLO-Y4 cells by an ERK1/2 MAP kinase-dependent mechanism.

  Bone 20030701

• Protein phosphorylation during the process of interaction of Toxoplasma gondii with host cells.

  Journal of submicroscopic cytology and pathology 20030701

• Toll-like receptors 2 and 4 activate STAT1 serine phosphorylation by distinct mechanisms in macrophages.

  The Journal of biological chemistry 20030620

• Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation.

  The Journal of biological chemistry 20030620

• Control of synaptic strength, a novel function of Akt.

  Neuron 20030619

• Biochemical characterization of the serum fetuin-mineral complex.

  The Journal of biological chemistry 20030613

• Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression.

  Science (New York, N.Y.) 20030613

• A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry.

  Analytical and bioanalytical chemistry 20030601

• Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.

  Diabetes 20030601

• Strategies and solid-phase formats for the analysis of protein and peptide phosphorylation employing a novel fluorescent phosphorylation sensor dye.

  Combinatorial chemistry & high throughput screening 20030601

• High-resolution structure of human phosphoserine phosphatase in open conformation.

  Acta crystallographica. Section D, Biological crystallography 20030601

• Inhibition of nuclear protein phosphatase activity in mouse hepatocytes by the cyanobacterial toxin microcystin-LR.

  Toxicon : official journal of the International Society on Toxinology 20030601

• Role of protein phosphatase 2C from bovine adrenal chromaffin cells in the dephosphorylation of phospho-serine 40 tyrosine hydroxylase.

  Journal of neurochemistry 20030601

• MAP kinases couple multiple functions of human progesterone receptors: degradation, transcriptional synergy, and nuclear association.

  The Journal of steroid biochemistry and molecular biology 20030601

• High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases.

  Assay and drug development technologies 20030601

• ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1.

  The Journal of biological chemistry 20030523

• Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells. Modulation of EGF-induced trafficking and signaling.

  The Journal of biological chemistry 20030523

• High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells.

  The Journal of biological chemistry 20030523

• Distinct mechanisms for regulating the tumor suppressor and antiapoptotic functions of Rb.

  The Journal of biological chemistry 20030523

• Differentiation-dependent up-regulation of p47(phox) gene transcription is associated with changes in PU.1 phosphorylation and increased binding affinity.

  Biochemical and biophysical research communications 20030523

• Effect of caspase cleavage-site phosphorylation on proteolysis.

  The Biochemical journal 20030515

• p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination.

  Cancer research 20030515

• Physical parameters of hydroxyapatite adsorption and effect on candidacidal activity of histatins.

  Archives of oral biology 20030501

• IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress.

  Diabetologia 20030501

• Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism.

  The Journal of biological chemistry 20030418

• Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast.

  Science (New York, N.Y.) 20030418

• DNA-dependent acetylation of p53 by the transcription coactivator p300.

  The Journal of biological chemistry 20030411

• Phosphorylation of the Ras-GRF1 exchange factor at Ser916/898 reveals activation of Ras signaling in the cerebral cortex.

  The Journal of biological chemistry 20030411

• Tumor promoter arsenite stimulates histone H3 phosphoacetylation of proto-oncogenes c-fos and c-jun chromatin in human diploid fibroblasts.

  The Journal of biological chemistry 20030411

• Phosphorylation of serine 1106 in the catalytic domain of topoisomerase II alpha regulates enzymatic activity and drug sensitivity.

  The Journal of biological chemistry 20030411

• An experimental and theoretical study of the 13C and 31P chemical shielding tensors in solid O-phosphorylated amino acids.

  Journal of the American Chemical Society 20030409

• Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling.

  The Journal of biological chemistry 20030404

• Expression of IGF-binding protein-1 phosphoisoforms in fasted rat skin and its role in regulation of collagen biosynthesis.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030401

• IRAK-dependent phosphorylation of Stat1 on serine 727 in response to interleukin-1 and effects on gene expression.

  Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20030401

• Determination of the post-translational modifications of salivary acidic proline-rich proteins.

  European journal of morphology 20030401

• Phosphatase activity characterization on the surface of intact bloodstream forms of Trypanosoma brucei.

  FEMS microbiology letters 20030328

• Mutants of phosphorylase a altered in recognition by protein phosphatase-1.

  Biochemistry 20030318

• Approaches to define antigen receptor-induced serine kinase signal transduction pathways.

  The Journal of biological chemistry 20030314

• Mechanisms underlying increases in SR Ca2+-ATPase activity after exercise in rat skeletal muscle.

  American journal of physiology. Endocrinology and metabolism 20030301

• New perspectives on the regulation of intermembrane glycerophospholipid traffic.

  Journal of lipid research 20030301

• Sites of phosphorylation of P and V proteins from Hendra and Nipah viruses: newly emerged members of Paramyxoviridae.

  Virus research 20030301

• Direct and indirect interactions between cannabinoid CB1 receptor and group II metabotropic glutamate receptor signalling in layer V pyramidal neurons from the rat prefrontal cortex.

  The European journal of neuroscience 20030301

• Z-FA-fmk inhibits effector caspases but not initiator caspases 8 and 10, and demonstrates that novel anticancer retinoid-related molecules induce apoptosis via the intrinsic pathway.

  Molecular cancer therapeutics 20030301

• Membrane-bound acid phosphatase (MAP) from Entamoeba histolytica has phosphotyrosine phosphatase activity and disrupts the actin cytoskeleton of host cells.

  Parasitology 20030301

• Seizures induced by homocysteic acid in immature rats are prevented by group III metabotropic glutamate receptoragonist (R,S)-4-phosphonophenylglycine.

  Experimental neurology 20030301

• Human recombinant anti-La (SS-B) autoantibodies demonstrate the accumulation of phosphoserine-366-containing la isoforms in nucleoplasmic speckles.

  European journal of cell biology 20030301

• Histone H3 is aberrantly phosphorylated in glutamine-repeat diseases.

  Biochemical and biophysical research communications 20030227

• Reconstitution of water channel function of an aquaporin overexpressed and purified from Pichia pastoris.

  FEBS letters 20030227

• Proteomic screen finds pSer/pThr-binding domain localizing Plk1 to mitotic substrates.

  Science (New York, N.Y.) 20030221

• Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.

  Blood 20030215

• Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030201

• Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17.

  The Journal of biological chemistry 20030131

• The requirement of specific membrane domains for Raf-1 phosphorylation and activation.

  The Journal of biological chemistry 20030131

• Phosphorylation of serine residues is fundamental for the calcium-binding ability of Orchestin, a soluble matrix protein from crustacean calcium storage structures.

  FEBS letters 20030130

• Analysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodies.

  The Journal of biological chemistry 20030124

• Lithium chloride, administered chronically to rats, does not affect the fractional phosphorylation of brain cytosolic phospholipase A2, while reducing its net protein level.

  Brain research bulletin 20030115

• Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12.

  Nature 20030109

• PBX1 nuclear export is regulated independently of PBX-MEINOX interaction by PKA phosphorylation of the PBC-B domain.

  The EMBO journal 20030102

• Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen.

  American journal of physiology. Endocrinology and metabolism 20030101

• Protein phosphatase-2A restricts migration of Lewis lung carcinoma cells by modulating the phosphorylation of focal adhesion proteins.

  International journal of cancer 20030101

• Synthesis and immunogenic properties of phosphopeptides related to the human insulin receptor.

  The journal of peptide research : official journal of the American Peptide Society 20030101

• Chemical modifications of proteins as an aid to sequence analysis.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Analysis of sites of protein phosphorylation.

  Methods in molecular biology (Clifton, N.J.) 20030101

• Metal ion complexes in the structural analysis of phospholipids by electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20030101

• The prolyl isomerase Pin1 in breast development and cancer.

  Breast cancer research : BCR 20030101

• Analysis of class I phosphoinositide 3-kinase autophosphorylation sites by mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20030101

• A novel Leishmania infantum nuclear phosphoprotein Lepp12 which stimulates IL1-beta synthesis in THP-1 transfectants.

  BMC microbiology 20030101

• Molecular plasticity in the rat auditory brainstem: modulation of expression and distribution of phosphoserine, phospho-CREB and TrkB after noise trauma.

  Audiology & neuro-otology 20030101

• Expression of Drosophila FOXO regulates growth and can phenocopy starvation.

  BMC developmental biology 20030101

• Stable isotope labeling of phosphopeptides for multiparallel kinase target analysis and identification of phosphorylation sites.

  Rapid communications in mass spectrometry : RCM 20030101

• Protein phosphatase-2A regulates protein tyrosine phosphatase activity in Lewis lung carcinoma tumor variants.

  Clinical & experimental metastasis 20030101

• Distribution and potential role of cytosolic water-soluble phosphodiesters in fish.

  Physiological and biochemical zoology : PBZ 20030101

• Expressed sequence tag analysis in Cycas, the most primitive living seed plant.

  Genome biology 20030101

• Gamma irradiation results in phosphorylation of p53 at serine-392 in human T-lymphocyte leukaemia cell line MOLT-4.

  Folia biologica 20030101

• Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts.

  Experimental & molecular medicine 20021231

• A tumor-specific kinase activity regulates the viral death protein Apoptin.

  The Journal of biological chemistry 20021227

• 14-3-3 binding to the IGF-1 receptor is mediated by serine autophosphorylation.

  FEBS letters 20021218

• Bcr: a negative regulator of the Bcr-Abl oncoprotein in leukemia.

  Oncogene 20021209

• Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43.

  Journal of cellular physiology 20021201

• Phosphorylation activates Chk1 and is required for checkpoint-mediated cell cycle arrest.

  Journal of cell science 20021201

• Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.

  Endocrinology 20021201

• A role for casein kinase 2alpha in the Drosophila circadian clock.

  Nature 20021201

• Cocaine treatment- and withdrawal-induced alterations in the expression and serine phosphorylation of the NR1 NMDA receptor subunit.

  Psychopharmacology 20021201

• The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase.

  Biological chemistry 20021201

• Identification of phosphorylated and glycosylated sites in peptides by chemically targeted proteolysis.

  Journal of biomolecular techniques : JBT 20021201

• Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase.

  The Journal of biological chemistry 20021129

• TFIIF-associating carboxyl-terminal domain phosphatase dephosphorylates phosphoserines 2 and 5 of RNA polymerase II.

  The Journal of biological chemistry 20021129

• A new dipeptide, O-phosphoserylethanolamine isolated from Agkistroden blomhoffi (mamushi).

  Archives of biochemistry and biophysics 20021115

• Dissection of c-MOS degron.

  The EMBO journal 20021115

• Identification of phosphoserine and phosphothreonine as cysteic acid and beta-methylcysteic acid residues in peptides by tandem mass spectrometric sequencing.

  Analytical chemistry 20021115

• Phosphorylation of Nrf2 at Ser-40 by protein kinase C regulates antioxidant response element-mediated transcription.

  The Journal of biological chemistry 20021108

• Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.

  The Journal of biological chemistry 20021108

• Identification and functional analysis of novel phosphorylation sites in Cx43 in rat primary granulosa cells.

  FEBS letters 20021106

• Regulated protein-protein interaction between aPKC and PAR-3 plays an essential role in the polarization of epithelial cells.

  Genes to cells : devoted to molecular & cellular mechanisms 20021101

• Increased methamphetamine-induced locomotor activity and behavioral sensitization in histamine-deficient mice.

  Journal of neurochemistry 20021101

• Drosophila 14-3-3/PAR-5 is an essential mediator of PAR-1 function in axis formation.

  Developmental cell 20021101

• Identification of phosphorylation sites in the polo-like kinases Plx1 and Plk1 by a novel strategy based on element and electrospray high resolution mass spectrometry.

  Proteomics 20021101

• Decorin affects endothelial cells by Akt-dependent and -independent pathways.

  Annals of the New York Academy of Sciences 20021101

• Regulation of catalase enzyme activity by cell signaling molecules.

  Molecular and cellular biochemistry 20021101

• Self-assembly of highly phosphorylated silaffins and their function in biosilica morphogenesis.

  Science (New York, N.Y.) 20021018

• A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.

  The EMBO journal 20021015

• Quantitative detection of (125)IdU-induced DNA double-strand breaks with gamma-H2AX antibody.

  Radiation research 20021001

• The SPOT technique as a tool for studying protein tyrosine phosphatase substrate specificities.

  Protein science : a publication of the Protein Society 20021001

• Myelin proteolipid protein, basic protein, the small isoform of myelin-associated glycoprotein, and p42MAPK are associated in the Triton X-100 extract of central nervous system myelin.

  Journal of neuroscience research 20021001

• Crystal structure of a human mitochondrial deoxyribonucleotidase.

  Nature structural biology 20021001

• 14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin.

  Current biology : CB 20021001

• Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001

• Amphetamine increases phosphorylation of extracellular signal-regulated kinase and transcription factors in the rat striatum via group I metabotropic glutamate receptors.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021001

• Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

  Journal of leukocyte biology 20021001

• Identification and characterization of a mammalian 14-kDa phosphohistidine phosphatase.

  European journal of biochemistry 20021001

• Retinoic acid modulates gap junctional intercellular communication in hepatocytes and hepatoma cells.

  Cellular and molecular life sciences : CMLS 20021001

• PrpE, a PPP protein phosphatase from Bacillus subtilis with unusual substrate specificity.

  The Biochemical journal 20020915

• The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes.

  The Journal of biological chemistry 20020913

• Interaction of 14-3-3 protein with regulator of G protein signaling 7 is dynamically regulated by tumor necrosis factor-alpha.

  The Journal of biological chemistry 20020906

• Protein serine and threonine phosphorylation, hyperactivation and acrosome reaction in in vitro capacitated hamster spermatozoa.

  Molecular reproduction and development 20020901

• Phosphorylation of neuronal nitric oxide synthase at Ser847 by CaM-KII in the hippocampus of rat brain after transient forebrain ischemia.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020901

• Gas phase reactions of trimethyl borate with phosphates and their non-covalent complexes.

  Journal of the American Society for Mass Spectrometry 20020901

• pGp as the main product of bovine tRNA kinase.

  Molecular biology reports 20020901

• Regulation of histone deacetylase 2 by protein kinase CK2.

  The Journal of biological chemistry 20020830

• General method for the synthesis of caged phosphopeptides: tools for the exploration of signal transduction pathways.

  Organic letters 20020822

• Antibody-based fluorescence detection of kinase activity on a peptide array.

  Bioorganic & medicinal chemistry letters 20020819

• Stereoselective synthesis of alpha-monofluorinated phosphonate mimetics of naturally occurring phosphoserine and phosphothreonine, via electrophilic fluorination of lithiated bis-lactim ethers.

  Chemical communications (Cambridge, England) 20020807

• Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line.

  The Journal of biological chemistry 20020802

• Oocyte fertilization triggers acid phosphatase activity during Rhodnius prolixus embryogenesis.

  Insect biochemistry and molecular biology 20020801

• Resveratrol induced serine phosphorylation of p53 causes apoptosis in a mutant p53 prostate cancer cell line.

  The Journal of urology 20020801

• Measurement of IKK activity in primary rat T cells: rapid activation and inactivation.

  Journal of immunological methods 20020801

• Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.

  Diabetes 20020801

• Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.

  The EMBO journal 20020801

• Lithium regulates protein tyrosine phosphatase activity in vitro and in vivo.

  Psychopharmacology 20020801

• In vivo and in vitro phosphorylation of membrane and soluble forms of soybean nodule sucrose synthase.

  Plant physiology 20020801

• Exoenzyme S binds its cofactor 14-3-3 through a non-phosphorylated motif.

  Biochemical Society transactions 20020801

• The activation of metabotropic glutamate receptors differentially affects GABA and alpha-melanocyte stimulating hormone release from the hypothalamus and the posterior pituitary of male rats.

  Neuroscience letters 20020719

• Tk-PTP, protein tyrosine/serine phosphatase from hyperthermophilic archaeon Thermococcus kodakaraensis KOD1: enzymatic characteristics and identification of its substrate proteins.

  Biochemical and biophysical research communications 20020712

• The death domain of NF-kappa B1 p105 is essential for signal-induced p105 proteolysis.

  The Journal of biological chemistry 20020705

• Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation.

  The Journal of biological chemistry 20020705

• AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signaling.

  The Journal of biological chemistry 20020705

• Caught in the act: the structure of phosphorylated beta-phosphoglucomutase from Lactococcus lactis.

  Biochemistry 20020702

• Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism.

  Nature structural biology 20020701

• Neutrophil transepithelial migration: evidence for sequential, contact-dependent signaling events and enhanced paracellular permeability independent of transjunctional migration.

  Journal of immunology (Baltimore, Md. : 1950) 20020701

• A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.

  The EMBO journal 20020701

• Formation of an hER alpha-COUP-TFI complex enhances hER alpha AF-1 through Ser118 phosphorylation by MAPK.

  The EMBO journal 20020701

• Activation of group III metabotropic glutamate receptors inhibits the production of RANTES in glial cell cultures.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020701

• Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol.

  Molecular carcinogenesis 20020701

• Control of the glycolytic gapA operon by the catabolite control protein A in Bacillus subtilis: a novel mechanism of CcpA-mediated regulation.

  Molecular microbiology 20020701

• Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues.

  European journal of biochemistry 20020701

• A novel precursor ion discovery method on a hybrid quadrupole orthogonal acceleration time-of-flight (Q-TOF) mass spectrometer for studying protein phosphorylation.

  Journal of the American Society for Mass Spectrometry 20020701

• Secondary structural studies of bovine caseins: structure and temperature dependence of beta-casein phosphopeptide (1-25) as analyzed by circular dichroism, FTIR spectroscopy, and analytical ultracentrifugation.

  Journal of protein chemistry 20020701

• A mass spectrometry-based proteomic approach for identification of serine/threonine-phosphorylated proteins by enrichment with phospho-specific antibodies: identification of a novel protein, Frigg, as a protein kinase A substrate.

  Molecular & cellular proteomics : MCP 20020701

• Expression and characterization of GSK-3 mutants and their effect on beta-catenin phosphorylation in intact cells.

  The Journal of biological chemistry 20020628

• The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status.

  The Journal of biological chemistry 20020621

• Biphasic regulation of extracellular-signal-regulated protein kinase by leptin in macrophages: role in regulating STAT3 Ser727 phosphorylation and DNA binding.

  The Biochemical journal 20020615

• Cyclin-dependent kinase 5 phosphorylates disabled 1 independently of Reelin signaling.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20020615

• Characterization of the CTD phosphatase Fcp1 from fission yeast. Preferential dephosphorylation of serine 2 versus serine 5.

  The Journal of biological chemistry 20020614

• Promoter of FGF8 reveals a unique regulation by unliganded RARalpha.

  Journal of molecular biology 20020607

• alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.

  American journal of physiology. Heart and circulatory physiology 20020601

• Phosphorylation-activity relationships of AMPK and acetyl-CoA carboxylase in muscle.

  Journal of applied physiology (Bethesda, Md. : 1985) 20020601

• Natural variation in the extent of phosphorylation of bone phosphoproteins as a function of in vivo new bone formation induced by demineralized bone matrix in soft tissue and bony environments.

  The Biochemical journal 20020601

• Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation.

  Genes & development 20020601

• Phosphorylation of the movement protein of cucumber mosaic virus in transgenic tobacco plants.

  Virus genes 20020601

• mRNA differential display of gene expression in colonic carcinoma.

  Electrophoresis 20020601

• Cardioprotective effect of coconut kernel protein in isoproterenol administered rats.

  Indian journal of biochemistry & biophysics 20020601

• Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic 'snapshots' of intermediate states.

  Journal of molecular biology 20020531

• Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways.

  Cell 20020517

• Phosphorylation and flexibility of cyclic-AMP-dependent protein kinase (PKA) using (31)P NMR spectroscopy.

  Biochemistry 20020514

• Rapamycin partially prevents insulin resistance induced by chronic insulin treatment.

  Biochemical and biophysical research communications 20020510

• Aurora-B associated protein phosphatases as negative regulators of kinase activation.

  Oncogene 20020509

• Histone H3 phosphorylation during Xenopus oocyte maturation: regulation by the MAP kinase/p90Rsk pathway and uncoupling from DNA condensation.

  FEBS letters 20020508

• Effect of phosphorylation on the structure and fold of transactivation domain of p53.

  The Journal of biological chemistry 20020503

• Vav1 couples T cell receptor to serum response factor-dependent transcription via a MEK-dependent pathway.

  The Journal of biological chemistry 20020503

• Growth-dependent regulation of mammalian pyrimidine biosynthesis by the protein kinase A and MAPK signaling cascades.

  The Journal of biological chemistry 20020503

• Protein kinase C inhibits type VI adenylyl cyclase by phosphorylating the regulatory N domain and two catalytic C1 and C2 domains.

  The Journal of biological chemistry 20020503

• Supersensitivity of human metabotropic glutamate 1a receptor signaling in L929sA cells.

  Molecular pharmacology 20020501

• Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501

• Monitoring the interfacial capacitance at self-assembled phosphate monolayers on gold electrodes upon interaction with calcium and magnesium.

  Analytical chemistry 20020501

• A rapid extraction procedure of human hair proteins and identification of phosphorylated species.

  Biological & pharmaceutical bulletin 20020501

• Expression and localization of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.

  Research in microbiology 20020501

• Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein.

  Biochemistry 20020430

• Increased serine phosphorylation and activation of STAT1 by oncogenic Ras transfection.

  Molecules and cells 20020430

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Molecular dynamics characterization of the C2 domain of protein kinase Cbeta.

  The Journal of biological chemistry 20020412

• Isolation of a cDNA for a nucleoside diphosphate kinase capable of phosphorylating the kinase domain of the self-incompatibility factor SRK of Brassica campestris.

  Journal of experimental botany 20020401

• Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020401

• Interaction between vanilloid and glutamate receptors in the central modulation of nociception.

  European journal of pharmacology 20020329

• Nitric-oxide-synthase-mediated cyclic guanosine monophosphate production in neonatal rat cerebellar prisms is resistant to calcineurin inhibition.

  Neuroscience letters 20020329

• Phosphorylation of HDM2 by Akt.

  Oncogene 20020327

• Apolipoprotein E activates Akt pathway in neuro-2a in an isoform-specific manner.

  Biochemical and biophysical research communications 20020322

• A new strategy for caging proteins regulated by kinases.

  Journal of the American Chemical Society 20020320

• SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression.

  Mutation research 20020320

• Effect of protein kinase Cgamma on gap junction disassembly in lens epithelial cells and retinal cells in culture.

  Molecular vision 20020314

• Defective Akt activation is associated with glucose- but not glucosamine-induced insulin resistance.

  American journal of physiology. Endocrinology and metabolism 20020301

• From structure to function: YrbI from Haemophilus influenzae (HI1679) is a phosphatase.

  Proteins 20020301

• Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

  The Biochemical journal 20020301

• Cutting Edge: Internalization of transduced E-selectin by cultured human endothelial cells: comparison of dermal microvascular and umbilical vein cells and identification of a phosphoserine-type di-leucine motif.

  Journal of immunology (Baltimore, Md. : 1950) 20020301

• Caffeine-induced impairment of insulin action but not insulin signaling in human skeletal muscle is reduced by exercise.

  Diabetes 20020301

• 14-3-3 facilitates insulin-stimulated intracellular trafficking of insulin receptor substrate 1.

  Molecular endocrinology (Baltimore, Md.) 20020301

• Expression of phosphatidylserine receptor and down-regulation of pro-inflammatory molecule production by its natural ligand in rat microglial cultures.

  Journal of neuropathology and experimental neurology 20020301

• Store depletion-induced calcium influx in rat cerebellar astrocytes.

  British journal of pharmacology 20020301

• Fragmentation of phosphopeptides by atmospheric pressure MALDI and ESI/Ion trap mass spectrometry.

  Journal of the American Society for Mass Spectrometry 20020301

• Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20.

  Oncogene 20020227

• Four hydrophobic amino acids of the factor VIII C2 domain are constituents of both the membrane-binding and von Willebrand factor-binding motifs.

  The Journal of biological chemistry 20020222

• Identification of a novel phosphorylation site, Ser-170, as a regulator of bad pro-apoptotic activity.

  The Journal of biological chemistry 20020222

• Active Rho kinase (ROK-alpha ) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells.

  The Journal of biological chemistry 20020222

• Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2.

  The Journal of biological chemistry 20020222

• Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.

  The Journal of biological chemistry 20020222

• Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase.

  Journal of immunology (Baltimore, Md. : 1950) 20020215

• Effect of phosphorylation on alpha-helix stability as a function of position.

  Biochemistry 20020212

• Activation of ATM and phosphorylation of p53 by heat shock.

  Oncogene 20020207

• Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms: role of protein kinase A.

  The Journal of biological chemistry 20020201

• Inhibition of protein phosphatase-1 is linked to phosphorylation of p53 and apoptosis.

  Apoptosis : an international journal on programmed cell death 20020201

• Ser-474 is the major target of insulin-mediated phosphorylation of protein kinase B beta in primary rat adipocytes.

  Cellular signalling 20020201

• The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes.

  Molecular endocrinology (Baltimore, Md.) 20020201

• Signal transduction and the control of gene expression.

  Science (New York, N.Y.) 20020201

• Phosphorylation of retinoid X receptor suppresses its ubiquitination in human hepatocellular carcinoma.

  Hepatology (Baltimore, Md.) 20020201

• Phosphopeptide detection and sequencing by matrix-assisted laser desorption/ionization quadrupole time-of-flight tandem mass spectrometry.

  Journal of mass spectrometry : JMS 20020201

• Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

  Oncogene 20020131

• Sendai virus C protein impairs both phosphorylation and dephosphorylation processes of Stat1.

  FEBS letters 20020130

• Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function.

  The Journal of biological chemistry 20020125

• Structural features underlying the multisite phosphorylation of the A domain of the NF-AT4 transcription factor by protein kinase CK1.

  Biochemistry 20020115

• Inhibition of the Bcr-Abl oncoprotein by Bcr requires phosphoserine 354.

  Cancer research 20020115

• The capsid protein of a plant single-stranded RNA virus is modified by O-linked N-acetylglucosamine.

  The Journal of biological chemistry 20020104

• Isolation and characterization of a protein-tyrosine kinase and a phosphotyrosine-protein phosphatase from Klebsiella pneumoniae.

  Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020101

• p38-Dependent marking of inflammatory genes for increased NF-kappa B recruitment.

  Nature immunology 20020101

• Purification, crystallization and preliminary X-ray diffraction analysis of human phosphoserine phosphatase.

  Acta crystallographica. Section D, Biological crystallography 20020101

• Preparing the target for the bullet.

  Nature immunology 20020101

• A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.

  Diabetes 20020101

• Phosphoserine-dependent regulation of protein-protein interactions in the Smad pathway.

  Structure (London, England : 1993) 20020101

• MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

  BMC cell biology 20020101

• Selective effect of cholesterylphosphoserine on intracellular cholesterol transport.

  Lipids 20020101

• Endogenous regucalcin suppresses the enhancement of protein phosphatase activity in the cytosol and nucleus of kidney cortex in calcium-administered rats.

  Journal of cellular biochemistry 20020101

• Hisactophilin is involved in osmoprotection in Dictyostelium.

  BMC biochemistry 20020101

• Identification of protein tyrosine phosphatase 1B and casein as substrates for 124-v-Mos.

  BMC biochemistry 20020101

• The regulation of protein synthesis and translation factors by CD3 and CD28 in human primary T lymphocytes.

  BMC biochemistry 20020101

• MAP kinase phosphatases.

  Genome biology 20020101

• The 14-3-3s.

  Genome biology 20020101

• Protein phosphatase-2A modulates the serine and tyrosine phosphorylation of paxillin in Lewis lung carcinoma tumor variants.

  Clinical & experimental metastasis 20020101

• Trypanosoma cruzi: in vitro phosphorylation of tubulin by a protein kinase CK2-like enzyme.

  Experimental parasitology 20020101

• A pool of beta-tubulin is hyperphosphorylated at serine residues in Alzheimer disease brain.

  FEBS letters 20011214

• Prenatal exposure to cocaine disrupts D1A dopamine receptor function via selective inhibition of protein phosphatase 1 pathway in rabbit frontal cortex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20011201

• Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.

  Diabetes 20011201

• 14-3-3 inhibits Bad-induced cell death through interaction with serine-136.

  Molecular pharmacology 20011201

• Development and validation of a competitive AKT serine/threonine kinase fluorescence polarization assay using a product-specific anti-phospho-serine antibody.

  Analytical biochemistry 20011201

• Akt activation by estrogen in estrogen receptor-negative breast cancer cells.

  Cancer research 20011201

• The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

  Structure (London, England : 1993) 20011201

• Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism.

  Journal of neurochemistry 20011201

• Crystal structure of a phosphorylated Smad2. Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-beta signaling.

  Molecular cell 20011201

• Structural basis of Smad1 activation by receptor kinase phosphorylation.

  Molecular cell 20011201

• The S. pombe aurora-related kinase Ark1 associates with mitotic structures in a stage dependent manner and is required for chromosome segregation.

  Journal of cell science 20011201

• Phosphoserine modification of the enteropathogenic Escherichia coli Tir molecule is required to trigger conformational changes in Tir and efficient pedestal elongation.

  Molecular microbiology 20011201

• Self-assembling materials. Coated nanofibers copy what's bred in the bone.

  Science (New York, N.Y.) 20011123

• Self-assembly and mineralization of peptide-amphiphile nanofibers.

  Science (New York, N.Y.) 20011123

• Phosphopeptide derivatization signatures to identify serine and threonine phosphorylated peptides by mass spectrometry.

  Analytical chemistry 20011115

• cAMP response element-binding protein mediates thrombin-induced proliferation of vascular smooth muscle cells.

  Arteriosclerosis, thrombosis, and vascular biology 20011101

• Generation of a constitutively active fragment of PKN in microglia/macrophages after middle cerebral artery occlusion in rats.

  Journal of neurochemistry 20011101

• The liquid-state 31P-nuclear magnetic resonance study on microfiltrated milk.

  Journal of dairy science 20011101

• Effects of metabotropic glutamate receptor agonists and antagonists on D-aspartate release from mouse cerebral cortical and striatal slices.

  Neurochemical research 20011101

• Galpha(i2) enhances insulin signaling via suppression of protein-tyrosine phosphatase 1B.

  The Journal of biological chemistry 20011026

• Role of serine phosphorylation of Stat5a in prolactin-stimulated beta-casein gene expression.

  Molecular and cellular endocrinology 20011025

• Group I metabotropic glutamate receptor activation increases phosphorylation of cAMP response element-binding protein, Elk-1, and extracellular signal-regulated kinases in rat dorsal striatum.

  Brain research. Molecular brain research 20011019

• Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants: potential role of Ser 315 phosphorylation-dependent centrosome binding of p53.

  Oncogene 20011018

• The 2,3-bisphosphoglycerate-independent phosphoglycerate mutase from Trypanosoma brucei: metal-ion dependency and phosphoenzyme formation.

  FEMS microbiology letters 20011016

• PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization.

  The EMBO journal 20011015

• Cyclin A-CDK phosphorylates Sp1 and enhances Sp1-mediated transcription.

  The EMBO journal 20011015

• Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway.

  Science (New York, N.Y.) 20011012

• Regulation of Ca(2+)/calmodulin-dependent protein kinase kinase alpha by cAMP-dependent protein kinase: II. Mutational analysis.

  Journal of biochemistry 20011001

• Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor.

  Molecular endocrinology (Baltimore, Md.) 20011001

• Familial intrahepatic cholestasis 1: studies of localization and function.

  Hepatology (Baltimore, Md.) 20011001

• Expression of pyrimidine 5'-nucleotidase subclass I during erythrocyte maturation in rats.

  Journal of hematotherapy & stem cell research 20011001

• The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration.

  Psychopharmacology 20011001

• Phosphorylation of the 24p3 protein secreted from mouse uterus in vitro and in vivo.

  Journal of protein chemistry 20011001

• Protein phosphatase 2A interacts with the Src kinase substrate p130(CAS).

  Oncogene 20010920

• Human leptin activates PI3K and MAPK pathways in human peripheral blood mononuclear cells: possible role of Sam68.

  Cellular immunology 20010915

• Leucine and insulin activate p70 S6 kinase through different pathways in human skeletal muscle.

  American journal of physiology. Endocrinology and metabolism 20010901

• Oxidized low density lipoprotein inhibits macrophage apoptosis through activation of the PI 3-kinase/PKB pathway.

  Journal of lipid research 20010901

• Matrix Gla protein in Xenopus laevis: molecular cloning, tissue distribution, and evolutionary considerations.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010901

• Mechanism for the ethanol-dependent heat-induced dissociation of casein micelles.

  Journal of agricultural and food chemistry 20010901

• Polypeptide synthesis using an expressed peptide as a building block for condensation with a peptide thioester: application to the synthesis of phosphorylated p21Max protein(1-101).

  Journal of peptide science : an official publication of the European Peptide Society 20010901

• Phosphorylation of serine-rich protein encoded by open reading frame 3 of the TT virus genome.

  Biochemical and biophysical research communications 20010817

• Cell cycle regulation of myosin-V by calcium/calmodulin-dependent protein kinase II.

  Science (New York, N.Y.) 20010817

• Phosphorylation of Marburg virus VP30 at serines 40 and 42 is critical for its interaction with NP inclusions.

  Virology 20010815

• Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription.

  Science (New York, N.Y.) 20010810

• Multiple phosphorylation of membrane-associated calcium-dependent protein serine/threonine kinase in Streptomyces fradiae.

  FEMS microbiology letters 20010807

• Zipper-interacting protein kinase induces Ca(2+)-free smooth muscle contraction via myosin light chain phosphorylation.

  The Journal of biological chemistry 20010803

• Insulin stimulates tyrosine phosphorylation and inactivation of protein-tyrosine phosphatase 1B in vivo.

  The Journal of biological chemistry 20010803

• Interleukin 2 activates nuclear phospholipase Cbeta by mitogen-activated protein kinase-dependent phosphorylation in human natural killer cells.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010801

• Detection of calmodulin-binding proteins and calmodulin-dependent phosphorylation linked to calmodulin-dependent chemotaxis to folic and cAMP in Dictyostelium.

  Cellular signalling 20010801

• Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.

  Journal of neurochemistry 20010801

• Phosphorylation by PKA of a site unique to B-Raf kinase.

  Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 20010801

• The neuropeptide proctolin induces phosphorylation of a 30 kDa protein associated with the thin filament in crustacean muscle.

  The Journal of experimental biology 20010801

• Purification and structural determination of a phosphorylated peptide with anti-calcification and chitin-binding activities in the exoskeleton of the crayfish, Procambarus clarkii.

  Bioscience, biotechnology, and biochemistry 20010801

• A cGMP-dependent protein kinase assay for high throughput screening based on time-resolved fluorescence resonance energy transfer.

  Journal of biomolecular screening 20010801

• The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes.

  The Journal of biological chemistry 20010727

• Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1.

  Biochemistry 20010724

• Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid.

  European journal of pharmacology 20010720

• Phosphorylation of human plasma alpha2-Heremans-Schmid glycoprotein (human fetuin) in vivo.

  The Biochemical journal 20010715

• Mitochondrial targeted cytochrome P450 2E1 (P450 MT5) contains an intact N terminus and requires mitochondrial specific electron transfer proteins for activity.

  The Journal of biological chemistry 20010706

• Structure of the Bacillus cell fate determinant SpoIIAA in phosphorylated and unphosphorylated forms.

  Structure (London, England : 1993) 20010703

• Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain.

  The EMBO journal 20010702

• Structure of GSK3beta reveals a primed phosphorylation mechanism.

  Nature structural biology 20010701

• Elevated levels of group-III metabotropic glutamate receptors in the inferior colliculus of genetically epilepsy-prone rats following intracollicular administration of L-serine-O-phosphate.

  Journal of neurochemistry 20010701

• MALDI-PSD-MS analysis of the phosphorylation sites of caseinomacropeptide.

  Peptides 20010701

• The chloroplastic glutamine synthetase (GS-2) of tobacco is phosphorylated and associated with 14-3-3 proteins inside the chloroplast.

  Planta 20010701

• Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta.

  The Journal of biological chemistry 20010629

• DNA binding of TEA/ATTS domain factors is regulated by protein kinase C phosphorylation in human choriocarcinoma cells.

  The Journal of biological chemistry 20010629

• Modulation of the G protein regulator phosducin by Ca2+/calmodulin-dependent protein kinase II phosphorylation and 14-3-3 protein binding.

  The Journal of biological chemistry 20010629

• Signal transduction: signaling specificity- a complex affair.

  Science (New York, N.Y.) 20010629

• Effects of substitution at serine 40 of tyrosine hydroxylase on catecholamine binding.

  Biochemistry 20010619

• Secretory phospholipase A2 mediates cooperative prostaglandin generation by growth factor and cytokine independently of preceding cytosolic phospholipase A2 expression in rat gastric epithelial cells.

  The Journal of biological chemistry 20010615

• Possible implication of the Golgi apparatus casein kinase in the phosphorylation of vesicle docking protein p115 Ser-940: a study with peptide substrates.

  Biochemical and biophysical research communications 20010615

• Identification of a novel phosphorylation site in human androgen receptor by mass spectrometry.

  Biochemical and biophysical research communications 20010615

• Phosphorylation of plant actin-depolymerising factor by calmodulin-like domain protein kinase.

  FEBS letters 20010615

• Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition.

  Cell 20010615

• A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.

  Science (New York, N.Y.) 20010608

• Characterization of a novel serine/threonine protein phosphatase (PfPPJ) from the malaria parasite, Plasmodium falciparum.

  Molecular and biochemical parasitology 20010601

• Synergism between nitric oxide and hydrogen peroxide in the inhibition of platelet function: the roles of soluble guanylyl cyclase and vasodilator-stimulated phosphoprotein.

  Nitric oxide : biology and chemistry 20010601

• Helicobacter pylori induces apoptosis in human epithelial gastric cells by stress activated protein kinase pathway.

  Helicobacter 20010601

• Ectopic alphaIIbbeta3 integrin signaling involves 12-lipoxygenase- and PKC-mediated serine phosphorylation events in melanoma cells.

  Thrombosis and haemostasis 20010601

• GPx-1 gene delivery modulates NFkappaB activation following diverse environmental injuries through a specific subunit of the IKK complex.

  Antioxidants & redox signaling 20010601

• Inhibitory effect of regucalcin on protein phosphatase activity in the nuclei of rat kidney cortex.

  Journal of cellular biochemistry 20010601

• Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila.

  Nature 20010517

• ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation.

  The Journal of biological chemistry 20010511

• Ca2+-independent smooth muscle contraction. a novel function for integrin-linked kinase.

  The Journal of biological chemistry 20010511

• 14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange.

  The Journal of biological chemistry 20010511

• Reciprocal phosphorylation and regulation of endothelial nitric-oxide synthase in response to bradykinin stimulation.

  The Journal of biological chemistry 20010511

• TNF-alpha inhibits flow and insulin signaling leading to NO production in aortic endothelial cells.

  American journal of physiology. Cell physiology 20010501

• Protein kinase C-mediated desensitization of the neurokinin 1 receptor.

  American journal of physiology. Cell physiology 20010501

• The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase.

  The Biochemical journal 20010501

• Activation of group III mGluRs inhibits GABAergic and glutamatergic transmission in the substantia nigra pars reticulata.

  Journal of neurophysiology 20010501

• Interaction of phosphorylated tyrosine hydroxylase with 14-3-3 proteins: evidence for a phosphoserine 40-dependent association.

  Journal of neurochemistry 20010501

• Phosphopeptides derived from hen egg yolk phosvitin: effect of molecular size on the calcium-binding properties.

  Bioscience, biotechnology, and biochemistry 20010501

• Phosphoamino acid analysis.

  Current protocols in cell biology 20010501

• Detection of phosphorylation by enzymatic techniques.

  Current protocols in molecular biology 20010501

• Phosphoamino acid analysis.

  Current protocols in protein science 20010501

• Functional replacement of the essential ESS1 in yeast by the plant parvulin DlPar13.

  The Journal of biological chemistry 20010427

• Functional conservation of phosphorylation-specific prolyl isomerases in plants.

  The Journal of biological chemistry 20010427

• Dominant negative function by an alternatively spliced form of the interferon-inducible protein kinase PKR.

  The Journal of biological chemistry 20010427

• Different usage of the glycosaminoglycan attachment sites of biglycan.

  The Journal of biological chemistry 20010420

• Cyclic AMP inhibits Akt activity by blocking the membrane localization of PDK1.

  The Journal of biological chemistry 20010420

• HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA.

  The Journal of biological chemistry 20010420

• Phosphorylation of Ser363, Thr370, and Ser375 residues within the carboxyl tail differentially regulates mu-opioid receptor internalization.

  The Journal of biological chemistry 20010420

• Lysophosphatidic acid-independent platelet activation by low-density lipoprotein.

  FEBS letters 20010406

• BCR gene expression blocks Bcr-Abl induced pathogenicity in a mouse model.

  Oncogene 20010405

• Phosphoserine/threonine-binding domains.

  Current opinion in cell biology 20010401

• Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function.

  Blood 20010401

• A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha.

  Journal of biochemistry 20010401

• Enrichment analysis of phosphorylated proteins as a tool for probing the phosphoproteome.

  Nature biotechnology 20010401

• Protein kinase C delta regulates neural cell adhesion molecule polysialylation state in the rat brain.

  Journal of neurochemistry 20010401

• Structural and functional hot spots in cytokine receptors.

  International journal of hematology 20010401

• Phosphorylation-induced structural changes in the amyloid precursor protein cytoplasmic tail detected by NMR.

  Journal of molecular biology 20010330

• Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting.

  The Biochemical journal 20010315

• PhosphoSerine/threonine binding domains: you can't pSERious?

  Structure (London, England : 1993) 20010307

• Polyphosphoprotein from the adhesive pads of Mytilus edulis.

  Biochemistry 20010306

• Expression of l-3-phosphoserine phosphatase is regulated by reconstituted basement membrane.

  Biochemical and biophysical research communications 20010302

• Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.

  Journal of neuroscience research 20010301

• Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding.

  The EMBO journal 20010301

• ASK1-signaling promotes c-Myc protein stability during apoptosis.

  Biochemical and biophysical research communications 20010301

• Comparison of the binuclear metalloenzymes diphosphoglycerate-independent phosphoglycerate mutase and alkaline phosphatase: their mechanism of catalysis via a phosphoserine intermediate.

  Chemical reviews 20010301

• Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription.

  The Journal of biological chemistry 20010216

• Myosin I phosphorylation is increased by chemotactic stimulation.

  The Journal of biological chemistry 20010216

• Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis.

  The Journal of biological chemistry 20010216

• Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344, resulting in beta-arrestin- and clathrin-mediated receptor internalization.

  The Journal of biological chemistry 20010216

• 3-phosphoinositide-dependent protein kinase 1, an Akt1 kinase, is involved in dephosphorylation of Thr-308 of Akt1 in Chinese hamster ovary cells.

  The Journal of biological chemistry 20010216

• Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli.

  The Journal of biological chemistry 20010216

• Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents.

  FEBS letters 20010216

• Inhibition of p53-dependent transcription by BOX-I phospho-peptide mimetics that bind to p300.

  EMBO reports 20010215

• Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.

  Archives of biochemistry and biophysics 20010215

• HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201

• Precise amounts of a novel member of a phosphotransferase superfamily are essential for growth and normal morphology in Caulobacter crescentus.

  Molecular microbiology 20010201

• Tale of a tail kinase.

  Nature structural biology 20010201

• Nerve growth factor inhibits PC12 cell PDE 2 phosphodiesterase activity and increases PDE 2 binding to phosphoproteins.

  Journal of neurochemistry 20010201

• Dopamine D(2) receptors regulate tyrosine hydroxylase activity and phosphorylation at Ser40 in rat striatum.

  The European journal of neuroscience 20010201

• Kinase suppressor of ras is necessary for tumor necrosis factor alpha activation of extracellular signal-regulated kinase/mitogen-activated protein kinase in intestinal epithelial cells.

  Cancer research 20010201

• A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.

  Molecular cell 20010201

• NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100.

  Molecular cell 20010201

• Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.

  Molecular and cellular biochemistry 20010201

• Metabotropic glutamate receptors modulate GABA release from mouse hippocampal slices.

  Neurochemical research 20010201

• Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution.

  Structure (London, England : 1993) 20010110

• Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation.

  The Journal of biological chemistry 20010105

• Activation of dopamine D(1)-like receptor causes phosphorylation of alpha(1)-subunit of Na(+),K(+)-ATPase in rat renal proximal tubules.

  European journal of pharmacology 20010105

• Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.

  Neurochemistry international 20010101

• Novel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16.

  The Biochemical journal 20010101

• A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody.

  Journal of immunological methods 20010101

• On-membrane digestion of beta-casein for determination of phosphorylation sites by matrix-assisted laser desorption/ionization quadrupole/time-of-flight mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20010101

• Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway.

  RNA (New York, N.Y.) 20010101

• Osmotic stress-dependent serine phosphorylation of the histidine kinase homologue DokA.

  BMC biochemistry 20010101

• Suppressive role of endogenous regucalcin in the regulation of protein phosphatase activity in rat renal cortex cytosol.

  Journal of cellular biochemistry 20010101

• Molecular biology of the plastidic phosphorylated serine biosynthetic pathway in Arabidopsis thaliana.

  Amino acids 20010101

• Ser133 phosphate-KIX interactions in the CREB-CBP complex: an ab initio molecular dynamics study.

  European biophysics journal : EBJ 20010101

• Preparation and application of antibodies to phosphoamino acid sequences.

  Biopolymers 20010101

• Theoretical models of catalytic domains of protein phosphatases 1 and 2A with Zn2+ and Mn2+ metal dications and putative bioligands in their catalytic centers.

  Acta biochimica Polonica 20010101

• Selective analysis of phosphopeptides within a protein mixture by chemical modification, reversible biotinylation and mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20010101

• New monoclonal antibodies recognizing p53 protein phosphorylated by casein kinase II at serine 392.

  Folia biologica 20010101

• Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

  Neuroscience 20010101

• A novel tetratricopeptide repeat (TPR) containing PP5 serine/threonine protein phosphatase in the malaria parasite, Plasmodium falciparum.

  BMC microbiology 20010101

• How do sickle cells become dehydrated?

  The hematology journal : the official journal of the European Haematology Association 20010101

• Protein phosphatase 2A: variety of forms and diversity of functions.

  Acta biochimica Polonica 20010101

• Binding of [3H](2S,1'S,2'S)-2-(9-xanthylmethyl)-2-(2'-carboxycyclopropyl) glycine ([3H]LY341495) to cell membranes expressing recombinant human group III metabotropic glutamate receptor subtypes.

  Naunyn-Schmiedeberg's archives of pharmacology 20001201

• Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8.

  Brain research. Molecular brain research 19990420

• Plastidic pathway of serine biosynthesis. Molecular cloning and expression of 3-phosphoserine phosphatase from Arabidopsis thaliana.

  The Journal of biological chemistry 19990416

• Ligand binding to the amino-terminal domain of the mGluR4 subtype of metabotropic glutamate receptor.

  The Journal of biological chemistry 19990409

• Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.

  Brain research. Molecular brain research 19980101

• Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor.

  Neuropharmacology 19970201

• Cloning and characterization of a metabotropic glutamate receptor, mGluR4b.

  Neuropharmacology 19970101

• Pharmacological effects of phosphatidylserine enzymatically synthesized from soybean lecithin on brain functions in rodents.

  Journal of nutritional science and vitaminology 19960201

• [3H]-L-2-amino-4-phosphonobutyrate labels a metabotropic glutamate receptor, mGluR4a.

  British journal of pharmacology 19951201

• Serine-O-phosphate has affinity for type IV, but not type I, metabotropic glutamate receptor.

  Neuroreport 19930901

• Signal transduction, pharmacological properties, and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 19930401

• Role of phospholipids in reconstituted cytochrome P450 3A form and mechanism of their activation of catalytic activity.

  Biochemistry 19920707

• Two polychlorinated hydrocarbons cause phospholipid-dependent protein kinase C activation in vitro in the absence of calcium.

  Molecular carcinogenesis 19910101

• Reversal of scopolamine-induced amnesia by phosphatidylserine in rats.

  Psychopharmacology 19860101

• Calcium transport and phospholipid composition of microsomal fractions from denervated rat gastrocnemius.

  The Biochemical journal 19731201

• A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1).

  Molecular endocrinology (Baltimore, Md.)

• p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization.

  Molecular endocrinology (Baltimore, Md.)