-
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Toxicological sciences : an official journal of the Society of Toxicology 20140101
-
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach.
European journal of medicinal chemistry 20120701
-
Cyclodextrins as a chiral mobile phase additive in nano-liquid chromatography: comparison of reversed-phase silica monolithic and particulate capillary columns.
Analytical and bioanalytical chemistry 20120301
-
Flupirtine: Clinical pharmacology.
Journal of anaesthesiology, clinical pharmacology 20120101
-
Update on twice-daily bromfenac sodium sesquihydrate to treat postoperative ocular inflammation following cataract extraction.
Clinical ophthalmology (Auckland, N.Z.) 20120101
-
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology 20111201
-
In silico prediction of acyl glucuronide reactivity.
Journal of computer-aided molecular design 20111101
-
Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways.
Chemical reviews 20111012
-
Clinical pharmacokinetics of ketoprofen enantiomers in wild type of Cyp 2c8 and Cyp 2c9 patients with rheumatoid arthritis.
European journal of drug metabolism and pharmacokinetics 20110901
-
[Acute flank pain syndrome: a common presentation of acute renal failure in young men in Iceland].
Laeknabladid 20110401
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
Novel metabolic bioactivation mechanism for a series of anti-inflammatory agents (2,5-diaminothiophene derivatives) mediated by cytochrome p450 enzymes.
Drug metabolism and disposition: the biological fate of chemicals 20100901
-
Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs.
Chemical research in toxicology 20100816
-
Enantiomeric separation of 2-arylpropionic acid nonsteroidal anti-inflammatory drugs by HPLC with hydroxypropyl-beta-cyclodextrin as chiral mobile phase additive.
Biomedical chromatography : BMC 20100801
-
Single dose dipyrone for acute postoperative pain.
The Cochrane database of systematic reviews 20100101
-
Photodegradation mechanism of nonsteroidal anti-inflammatory drugs containing thiophene moieties: suprofen and tiaprofenic acid.
The journal of physical chemistry. B 20090813
-
Enantiomeric separation of acidic compounds by nano-liquid chromatography with methylated-beta-cyclodextrin as a mobile phase additive.
Journal of separation science 20090501
-
Binding of CYP2C9 with diverse drugs and its implications for metabolic mechanism.
Medicinal chemistry (Shariqah (United Arab Emirates)) 20090501
-
Chemoenzymatic and microbial dynamic kinetic resolutions.
Chirality 20090401
-
Mechanism-based inactivation of cytochrome P450 2C9 by tienilic acid and (+/-)-suprofen: a comparison of kinetics and probe substrate selection.
Drug metabolism and disposition: the biological fate of chemicals 20090101
-
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development.
Current medicinal chemistry 20090101
-
New NSAIDs-NO hybrid molecules with antiproliferative properties on human prostatic cancer cell lines.
Bioorganic & medicinal chemistry letters 20080815
-
Topical ocular delivery of NSAIDs.
The AAPS journal 20080601
-
Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment.
European journal of clinical pharmacology 20080201
-
Analysis of pharmacology data and the prediction of adverse drug reactions and off-target effects from chemical structure.
ChemMedChem 20070601
-
Differential suppression of menstrual fluid prostaglandin F2a, prostaglandin E2, 6-keto prostaglandin F1a and thromboxane B2 by suprofen in women with primary dysmenorrhea.
Prostaglandins & other lipid mediators 20070201
-
Nonaqueous capillary electrophoretic behavior of 2-aryl propionic acids in the presence of an achiral ionic liquid. A chemometric approach.
Journal of chromatography. A 20070105
-
Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use.
The Cochrane database of systematic reviews 20061018
-
Enantiomeric separation of acidic compounds using single-isomer amino cyclodextrin derivatives in nonaqueous capillary electrophoresis.
Electrophoresis 20060901
-
Vancomycin as chiral selector for enantioselective separation of selected profen nonsteroidal anti-inflammatory drugs in capillary liquid chromatography.
Chirality 20060801
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Predicting the pharmacokinetics of acyl glucuronides and their parent compounds in disease states.
Current drug metabolism 20060201
-
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Current drug metabolism 20051001
-
Use of vancomycin chiral stationary phase for the enantiomeric resolution of basic and acidic compounds by nano-liquid chromatography.
Journal of chromatography. A 20050715
-
Intramolecular electron transfer between tyrosine and tryptophan photosensitized by a chiral pi,pi* aromatic ketone.
Chemistry (Weinheim an der Bergstrasse, Germany) 20050520
-
Enantioseparation on mono(6A-n-allylamino-6A-deoxy)permethylated 3-cyclodextrin covalently bonded silica gel.
Journal of chromatography. A 20041203
-
Process modeling of the lipase-catalyzed dynamic kinetic resolution of (R, S)-suprofen 2,2,2-trifluoroethyl thioester in a hollow-fiber membrane.
Bioprocess and biosystems engineering 20041201
-
Cationic vesicles as chiral selector for enantioseparations of nonsteroidal antiinflammatory drugs by micellar electrokinetic chromatography.
Journal of chromatography. A 20040903
-
In vitro effects of risperidone and 9-hydroxy-risperidone on human platelet function, plasma coagulation, and fibrinolysis.
Clinical therapeutics 20040801
-
Monolithic silica columns with chemically bonded tert-butylcarbamoylquinine chiral anion-exchanger selector as a stationary phase for enantiomer separations.
Journal of chromatography. A 20040521
-
Synthesis of precursor of anti-inflammatory agents by using highly reactive zinc.
The Medical journal of Malaysia 20040501
-
UV-induced drug release from photoactive REV sensitized by suprofen.
Journal of controlled release : official journal of the Controlled Release Society 20040416
-
Optimization of sample stacking for the simultaneous determination of nonsteroidal anti-inflammatory drugs with a wall-coated histidine capillary column.
Electrophoresis 20040201
-
Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen.
Drug metabolism and disposition: the biological fate of chemicals 20031101
-
Dextrans--potential polymeric drug carriers for suprofen.
Die Pharmazie 20031101
-
Topically applied vitamin C and cysteine derivatives protect against UVA-induced photodegradation of suprofen in ex vivo pigskin.
Photochemistry and photobiology 20030401
-
Topical nonsteroidal anti-inflammatory therapy in ophthalmology.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101
-
Capillary electrochromatographic separation of non-steroidal anti-inflammatory drugs with a histidine bonded phase.
Journal of chromatography. A 20021227
-
Effects of anti-inflammatory drugs and preservatives on morphologic characteristics and migration of canine corneal epithelial cells in tissue culture.
Veterinary ophthalmology 20020601
-
[Cross-reaction potentials of ketoprofen].
Orvosi hetilap 20020512
-
Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.
Free radical biology & medicine 20020401
-
Experimental study on phototoxicity and the photosensitization potential of ketoprofen, suprofen, tiaprofenic acid and benzophenone and the photocross-reactivity in guinea pigs.
Photodermatology, photoimmunology & photomedicine 20020401
-
Differential binding mode of diverse cyclooxygenase inhibitors.
Journal of molecular graphics & modelling 20020301
-
Identification of drug-binding sites on human serum albumin using affinity capillary electrophoresis and chemically modified proteins as buffer additives.
Electrophoresis 20020301
-
Antibodies directed to drug epitopes to investigate the structure of drug-protein photoadducts. Recognition of a common photobound substructure in tiaprofenic acid/ketoprofen cross-photoreactivity.
Chemical research in toxicology 20011101
-
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients.
Immunopharmacology and immunotoxicology 20011101
-
Protective effects of suprofen and its methyl ester against inactivation of rabbit kidney carbonyl reductase by phenylglyoxal.
Journal of enzyme inhibition 20011101
-
Photocontact dermatitis to ketoprofen.
American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20010901
-
Enantioselective inhibition of the binding of rac-profens to human serum albumin induced by lithocholate.
Chirality 20010701
-
Disposition of suprofen enantiomers in the cat.
Veterinary journal (London, England : 1997) 20010701
-
Five cases of photocontact dermatitis due to topical ketoprofen: photopatch testing and cross-reaction study.
Photodermatology, photoimmunology & photomedicine 20010201
-
Mechanisms of drug photobinding to proteins: photobinding of suprofen to human serum albumin.
Toxicology in vitro : an international journal published in association with BIBRA 20010101
-
Single-dose dipyrone for acute postoperative pain.
The Cochrane database of systematic reviews 20010101
-
Inhibition of pilocarpine-induced aqueous humor flare, hypotony, and miosis by topical administration of anti-inflammatory and anesthetic drugs to dogs.
American journal of veterinary research 19980401
-
Effects of suprofen on the isolated perfused rat kidney.
Renal failure 19920101
-
The epidemiology of the acute flank pain syndrome from suprofen.
Clinical pharmacology and therapeutics 19891201
-
Immune hemolytic anemia associated with tolmetin and suprofen.
Transfusion 19890901
-
Renal effects of nonsteroidal anti-inflammatory drugs.
Agents and actions. Supplements 19880101
-
Suprofen-induced acute renal failure.
Texas medicine 19871201
-
Suprofen and renal failure.
Annals of internal medicine 19870501
-
Suprofen-induced transient flank pain and renal failure.
The New England journal of medicine 19870416
-
Suprofen-related nephrotoxicity. A distinct clinical syndrome.
Annals of internal medicine 19870201
-
Suprofen and acute renal failure.
Annals of internal medicine 19861201
-
Suprofen, acute renal failure, and hematuria.
Annals of internal medicine 19861101
-
Suprofen-induced acute renal failure.
Drug intelligence & clinical pharmacy 19861101
-
Skin sensitizing properties of arylalcanoic acids and their analogues.
Contact dermatitis 19790901
-
Nonsteroid anti-inflammatory agents: regulators of the phagocytic secretion of lysosomal enzymes from guinea-pig neutrophils.
The Journal of pharmacology and experimental therapeutics 19781101
