421-85-2 | Trifluoromethanesulfonamide

Packsize	Purity	Availability	Price	Discounted Price
2g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$18.00	$13.00
10g	98%	in stock	$24.00	$17.00
25g	98%	in stock	$59.00	$42.00
100g	98%	in stock	$235.00	$165.00
500g	98%	in stock	$972.00	$681.00

Description

• Catalog Number: AB80032
• Chemical Name: Trifluoromethanesulfonamide
• CAS Number: 421-85-2
• Molecular Formula: CH2F3NO2S
• Molecular Weight: 149.09228960000002
• MDL Number: MFCD00068714
• SMILES: FC(S(=O)(=O)N)(F)F

Computed Properties

• Complexity: 161
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• XLogP3: 0.1

Literature

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  Journal of medicinal chemistry 20120308

• Bis(tetra-phenyl-phospho-nium) bis-[N-(trifluoro-methyl-sulfon-yl)dithio-carbimato(2-)-κS,S']zincate(II).

  Acta crystallographica. Section E, Structure reports online 20120101

• Discovery of new chromone containing sulfonamides as potent inhibitors of bovine cytosolic carbonic anhydrase.

  Bioorganic & medicinal chemistry 20110601

• Synthesis of N-[2-(2,4-Difluorophenoxy)trifluoromethyl-3-pyridyl]sulfonamides and their inhibitory activities against secretory phospholipase A₂.

  Chemical & pharmaceutical bulletin 20110101

• 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII.

  Bioorganic & medicinal chemistry 20101101

• Synthesis and investigation of inhibition effect of fluorinated sulfonamide derivatives on carbonic anhydrase.

  European journal of medicinal chemistry 20100301

• Versatile Pd(OTf)2 x 2 H2O-catalyzed ortho-fluorination using NMP as a promoter.

  Journal of the American Chemical Society 20090610

• Titration calorimetry standards and the precision of isothermal titration calorimetry data.

  International journal of molecular sciences 20090601

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  Analytical chemistry 20090401

• Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor alpha agonists.

  Bioorganic & medicinal chemistry letters 20080115

• Development of efficient Lewis acid catalysts for intramolecular cycloaddition reactions of ester-tethered substrates.

  Chemical record (New York, N.Y.) 20070101

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  The journal of physical chemistry. B 20060316

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  Biochemical Society transactions 20051201

• Direct, facile aldehyde and ketone alpha-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts.

  The Journal of organic chemistry 20050708

• Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors.

  Journal of medicinal chemistry 20041230

• The synthesis and structure-activity relationships of 3-amino-4-benzylquinolin-2-ones; discovery of novel KCNQ2 channel openers.

  Bioorganic & medicinal chemistry letters 20040405

• Variations of acidic functions at position 2 and substituents at positions 4, 5 and 6 of the indole moiety and their effect on NMDA-glycine site affinity.

  European journal of medicinal chemistry 20031001

• Structure-based design and discovery of novel inhibitors of protein tyrosine phosphatases.

  Bioorganic & medicinal chemistry 20030417

• Synthesis and structural comparison of triaryl(sulfonylimino)pnictoranes.

  Inorganic chemistry 20020408