4212-49-1 | 5-Ethyluracil

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$15.00	$10.00
5g	95%	in stock	$18.00	$12.00
10g	95%	in stock	$22.00	$15.00
25g	95%	in stock	$27.00	$19.00
100g	95%	in stock	$53.00	$37.00
500g	95%	in stock	$249.00	$175.00

Description

• Catalog Number: AB60253
• Chemical Name: 5-Ethyluracil
• CAS Number: 4212-49-1
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.13992000000002
• MDL Number: MFCD00079187
• SMILES: CCc1c[nH]c(=O)[nH]c1=O

Computed Properties

• Complexity: 208
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.2

Literature

• Discovery of novel 5-(ethyl or hydroxymethyl) analogs of 2'-'up' fluoro (or hydroxyl) pyrimidine nucleosides as a new class of Mycobacterium tuberculosis, Mycobacterium bovis and Mycobacterium avium inhibitors.

  Bioorganic & medicinal chemistry 20120701

• Synthesis and properties of small interfering RNA duplexes carrying 5-ethyluridine residues.

  Molecular diversity 20110801

• Molecular PET imaging of HSV1-tk reporter gene expression using [18F]FEAU.

  Nature protocols 20070101

• 5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.

  Bioorganic & medicinal chemistry 20050315

• Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase.

  Journal of medicinal chemistry 20020912

• Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii.

  Biochemical pharmacology 19940817

• Synthesis, biotransformation, pharmacokinetics, and antiviral properties of 5-ethyl-5-halo-6-methoxy-5,6-dihydro-2'-deoxyuridine diastereomers.

  Biochemical pharmacology 19940429