42438-90-4 | L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$29.00	$20.00
1g	95%	in stock	$41.00	$29.00
5g	95%	in stock	$103.00	$72.00
10g	95%	in stock	$169.00	$118.00
25g	95%	in stock	$333.00	$233.00
100g	95%	in stock	$971.00	$680.00

Description

• Catalog Number: AF58069
• Chemical Name: L-1,2,3,4-Tetrahydronorharman-3-carboxylic acid
• CAS Number: 42438-90-4
• Molecular Formula: C12H12N2O2
• Molecular Weight: 216.2359
• MDL Number: MFCD00272641
• SMILES: OC(=O)[C@H]1NCc2c(C1)c1ccccc1[nH]2

Computed Properties

• Complexity: 295
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1
• XLogP3: -1.2

Literature

• Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.

  Bioorganic & medicinal chemistry 20111101

• A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency.

  Journal of medicinal chemistry 20100422

• (3S)-N-(L-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: synthesis, bioassay, 3D QSAR, and ADME analysis.

  Bioorganic & medicinal chemistry 20081101

• Assembly of beta-cyclodextrin with 3S-tetrahydro-beta-carboline-3-carboxylic acid and self-assembly of 6-(3'S-carboline-3'-carboxylaminoethylamino)-6-deoxy-beta-cyclodextrin: approaches to enhance anti-oxidation stability and anti-thrombotic potency.

  The journal of physical chemistry. B 20080925

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Synthesis and thrombolytic activity of carboline-3-carboxylic acid modified metabolites of Ala-Arg-Pro-Ala-Lys.

  Preparative biochemistry & biotechnology 20040201

• Synthesis and antithrombotic activity of carbolinecarboxyl RGD sequence.

  Bioorganic & medicinal chemistry letters 20020225