4294-16-0 | N6-Benzyladenosine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$48.00	$33.00
1g	98%	in stock	$58.00	$40.00
5g	98%	in stock	$162.00	$113.00
10g	98%	in stock	$307.00	$215.00
25g	98%	in stock	$617.00	$432.00

Description

• Catalog Number: AF56522
• Chemical Name: N6-Benzyladenosine
• CAS Number: 4294-16-0
• Molecular Formula: C17H19N5O4
• Molecular Weight: 357.3639
• MDL Number: MFCD00005740
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1ccccc1

Computed Properties

• Complexity: 466
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 26
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 5
• XLogP3: 1.1

Literature

• Effects of cytokinins, cytokinin ribosides and their analogs on the viability of normal and neoplastic human cells.

  Anticancer research 20111001

• Halogenation of N⁶-benzyladenosine decreases its cytotoxicity in human leukemia cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20101201

• N⁶-Alkyladenosines: Synthesis and evaluation of in vitro anticancer activity.

  Bioorganic & medicinal chemistry 20101201

• Anticancer activity of natural cytokinins: a structure-activity relationship study.

  Phytochemistry 20100801

• Characterization of pharmacologically active compounds that inhibit poliovirus and enterovirus 71 infectivity.

  The Journal of general virology 20081001

• Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives.

  Journal of medicinal chemistry 20080724

• Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.

  Journal of medicinal chemistry 20080410

• Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity.

  Bioorganic & medicinal chemistry 20080401

• Cytokinins in the bryophyte Physcomitrella patens: analyses of activity, distribution, and cytokinin oxidase/dehydrogenase overexpression reveal the role of extracellular cytokinins.

  Plant physiology 20071101

• Preparation, biological activity and endogenous occurrence of N6-benzyladenosines.

  Bioorganic & medicinal chemistry 20070601

• Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.

  Biochemical pharmacology 20070515

• Caspase inhibition and N6-benzyladenosine-induced apoptosis in HL-60 cells.

  Journal of cellular biochemistry 20010101

• 2-Substitution of N6-benzyladenosine-5'-uronamides enhances selectivity for A3 adenosine receptors.

  Journal of medicinal chemistry 19941014